Adobe Media Encoder CC do not work/start/load on Win8 x64
Solution #2 (as Eric Vinyard suggested):
1. Locate file: C:\Program Files (x86)\Common Files\Adobe\SLCache\X19zbGNfZmVhdHVyZXNf­Xw==.slc
2. Open it with a text editor (may need to open it as an admin as this is in Program Files directory)
3. Delete everything the file contains
4. Save and close
5. Set the 'Read Only' attribute for the file: Right Mouse - Preferences. On the first page that opens for you, look for Attributes at the bottom of this page and check 'Read Only'. Close with OK.