Red Epic, Adobe Premiere Editing Workflow
Drag all your r3d files into Adobe Media Encoder (or CineX Pro), transcode to ProRes 422 (Proxy) and then use these to make your edit in Premiere. Once done, make the proxy footage offline in your project window and then relink to the original files.

Make sure to keep your folder structures the same for the proxies so that relinking is just a 1-click process. Also think before about what resolution you're delivering in and use sequence settings to reflect this.

Also make sure you actually have room for the proxies on your desktop. The files will be smaller but still take up a significant amount of space.