How much SSDs to use on computer for DaVinci Resolve Studio?
Variant 2 is gonna use 2 SSD Simultaneously, Which means IF one SSD can read Data upto 500MB/s then Both of them is gonna use Double that!
Feels Awesome, right?
But, That is not the fact.... Disk C is Only Gonna Send Huge Amount of Data to RAM when A Software Located inside Disk C is Starting.... When Finished loading It's Gonna be Back to It's idle mode....


That 1-3MB/s Doesn't Really Matter at all to The scale of 500MB/s.
So You can go with 1 Big SSD rather than 2 SSDs.
I would Suggest Doing that, You can Save Some bucks!

Also in my case, I was Downloading a File in Disk C. That's Why it Jumped to 14MBp/s But Usually, Even when Resolve will be Running Speed will be Jumping around 1.8MB/s
I was Worried about Performance Just Like you, Months Ago... I changed my build, Switched to AMD R9 then... My Solution was... Giving the SSD it's Very Own Disk rather than Storing C:Local Drive On it! i Store Local drive in HDD, all The Small and Not-So-Performance-Needed Software in there... The Softwares on which I needed Performance (eg: Blender, Cinema 4D, Fusion) I Installed them inside a Folder In Disk X (Disk X is on SSD)