In Omaha Poker, can we use 0,1,3 or 4 hole cards when selecting the best 5 cards?
To answer you title question: No. You are obliged to use 2 and only 2 of your hole cards.

There are main 2 differences between Texas Hold'em and Omaha Hold'em.


The number of hole cards you have.
The number of hold cards you must use to create your final hand.


In Texas Hold'em you get 2 hole cards dealt to you, but are not required to use any of them to form your final 5 card hand.

In Omaha Hold'em you get 4 hole cards dealt to you, but are required to use 2 (and only 2) of them when forming your final 5 card hand.