Genotype - Market Card refills
Not until the end of the round. Pg. 10 of the rulebook:

(Assistant Cards are not refilled until the end of the Round.)

And pg. 12:

Discard the remaining Pea Plant Cards, Tool Cards, and Assistants. Refill Tool and Pea Plant Cards based on player count (see p. 3) and refill 3 face-up Assistants.

And reiterated on the &quot;reminders and clarifications&quot; section on pg. 13:

Tool Cards and Pea Plant Cards are only refilled during the End of the Round Reset, not when taken.