What happens in Android: Netrunner when your deck runs out and you need to draw a card?
If the Corporation player attempts to draw from his empty R&amp;D deck, he loses the game. From the rules PDF, page 3:


  ...the Runner wins if the Corporation must draw a card from his empty draw deck


The Runner simply loses the ability to draw more cards if his Stack is empty, but it's not a game-ender. You don't reshuffle.