How can I get rid of indestructible creatures with a Red and White deck?
There are a variety of general answers for indestructible permanents:


Exile effects, which are your real bread-and-butter for all kinds of removal.
Toughness-reducing effects against creatures.
Sacrifice effects.
"Tuck" (move to library) effects.
Bouncing permanents (temporary).
Stealing permanents: the indestructible thing isn't a problem if you control it, right?
Ability- and action- restricting cards like Pithing Needle and Pacifism, if all you're worried about is disabling a card rather than removing it from the battlefield.




White is probably the strongest color for dealing with indestructible permanents after they've resolved. Some of your options are:


Oblivion Ring and similar enchantments provide single-shot answers to any non-land permanent. Note, in particular, Grasp of Fate as the multiplayer-oriented variant.
Path to Exile and Swords to Plowshares are low-cost instant answers for creatures.
Return to Dust for is a nice two-for-one against artifacts and enchantments.
Final Judgement, Descend Upon the Sinful, and False Prophet are an exile-based sweeper.
Hallowed Burial and Terminus are "tuck"-based sweepers.
Condemn can "tuck" a troublesome creature, although only when it's attacking.
Pacifism effects may be good enough if you're just trying to get rid of a blocker or prevent a card from using its activated abilities; Faith&#39;s Fetters and Prison Term are probably the best choice there.
Angel of the Dire Hour can wipe out a wave of indestructible attackers.
Elesh Norn will clear out a lot of weenies even if they're indestructible.
Evangelize and a lot mana: steal all their stuff.
Gideon, Champion of Justice will exile everything else on the battlefield.
Oblation "tucks" any nonland permanent at the cost of giving your opponent more cards.


In red:


Chaos Warp can "tuck" anything.
Into the Core can answer indestructible artifacts like Darksteel Forge.
Apocalypse and Decree of Annihilation are exile-based sweepers.
Warp World and similar cards will remove the offending permanents, at the cost of giving your opponent new toys to replace them.
Insurrection will let you take all of an opponent's creatures for a turn &mdash; usually that's enough to finish off a player or feed them all to a sacrifice outlet like Ashnod&#39;s Altar so you don't have to give them back.


Colorless cards worth noting:


Duplicant is a popular card for exiling creatures.
Brittle Effigy, Amulet of Unmaking, and Helvault provide targeted exile effects, though not very cost-effectively compared to what you can get in white.
Karn Liberated and Ugin, the Spirit Dragon can easily exile multiple troublesome permanents.
All Is Dust is a sacrifice-based sweeper.