How would a "blocking" strategy play differently in Ticket to Ride than other strategies?
I think you have it mostly right already, and certainly it will vary based on the people involved, but in my experience the jump from players focusing on their own agenda to being more interested in disrupting their opponents means shorter tickets are better, there is likely to be a lot of hoarding up cards until someone has enough to actually pursue a route, the longest train will be shorter than in the first scenario, etcetera. In my experience if one player pursues a blocking strategy while the other tries to do their own thing, the "do my own thing" player will win more often than not. That may change when you get into higher numbers of players.