Does an action which gives you +2 Advance Civilization require they be used together?
Looking through the deck for similar cards to Padraigin-3110, I came across 1 essentially identical card, Nakagawakozi (spend energy to improve economy, rather than spending culture to improve diplomacy, but same general idea). I came across 2 other cards which allow you to regress a ship -2 (Jorg) or advance a ship +2 (Terra-Bettia).

Jorg specifically mentions that you must regress a single ship by -2. Terra-Bettia is a bit more ambiguous, but does mention advancing "a ship" +2, implying that it must be a single ship. 

In the absence of any clarifications from the designer / manufacturer, and given there are similar cards to Padraigin which specifically mention the action must be performed on a single ship, while Padraigin does not specifically mention the same, the benefit of Padraigin-3110 seems to be equivalent to rolling two separate dice, each containing the diplomacy symbol. Similarly, taking the action at Nakagawakozi would be equivalent to rolling two economy symbols on the dice. That is, you can advance one ship +2, or two ships +1.