Skip card - Phase 10
Yes.
The skip card does not have any special rules about when it can be played; you discard it the same way you play any other card; and it does something special when you do.

On your turn, draw one card, either the top card from the draw pile or the top card from the discard pile, and add it to your hand. End your turn by discarding any one of your cards onto the top of the discard pile.
SKIP CARDS: Skip cards have only one purpose: to cause
another player to lose a turn. To use, simply discard the “Skip” card on your turn, then choose the player who will lose a turn.