Rotation speed setting?
For this you need to do a little math. We need to find out how much the wheel spins withing 1 second. 

Let's say you render at 30fps and one rotation equals 360°. First we have convert rotations per minute into rotations per second. Then we have to convert rotations per second into degrees per second.

1000rpm / 60s = 16.667rps


We multiply 360° by 16.667rps to get how many degrees it spins in a second.

16.667rps * 360° = 6000°ps


The wheel spins ~6000° per second. To find out how many degrees it spins in a frame, divide the spins per second (6000°) by the number of frames per second (30fps).

6000° / 30 = 500°


The wheel needs to spin 500° per frame to complete 1000rpm.

To do that, go to frame 1 and set a keyframe at 0° rotation. Then set a keyframe at 500° rotation on frame 2. To make it continue speaking, location the rotation fcurve in the graph editor, select it and press &#8679; ShiftE > Linear Extrapolation. (See this related answer.)

You can also use this online calculator.