How to use dual scroll wheel mouse in Blender?
A hacky solution could be use AutoHotkey script:

*WheelLeft::Send % ((A_PriorHotkey=A_ThisHotkey)&amp;&amp;(A_TimeSincePriorHotkey&lt;20))?"":"{Blind}{F14}"
*WheelRight::Send % ((A_PriorHotkey=A_ThisHotkey)&amp;&amp;(A_TimeSincePriorHotkey&lt;20))?"":"{Blind}{F15}"


And then use HorizontalScroll as it was F14 and F15 that is normally unavailable in most keyboards. (it works with modifiers keys also)