Nothing happens when baking fluid simulation
Apply the scale to domain and inflow object. &#9096; CtrlA

Why is there an inverted sphere in the inflow? Remove it, it is going to give us some wrong direction otherwise.

And finally, your domain is very large compared to the preview resolution of 45. The inflow is so small that the emitted fluid is not visible.

Voxels (volume elements) are the smallest unit in the volumetric fluid simulation. Since the emitted fluid is smaller than a voxel, no geometry is created.

To solve this:


Scale up the inflow.
Scale down the domain.
Apply scale.
Increase the resolution.
Immediately switch to final resolution under viewport display. This is going to show us the final resoluted geometry.


Here are some more efficient scale at a final resolution of 200. Note how to domain will barely contain all of the fluid.