When I open blender I have some issues
It seems that your startup file has some issues. You can go back to the factory startup file by doing the following:

Go to File &gt; Defaults &gt; Load Factory Settings. This loads in the startup file that would come with a new installation of Blender.
Go to File &gt; Defaults &gt; Save Startup File. This saves the current .blend file (in this case, the factory one you just loaded) as the startup one.
If 1 and 2 do not solve your problem, you may also have to reset your preferences by going to Edit &gt; Preferences (while in the factory file), click on the menu button in the bottom left corner, and click Save Preferences.
If 1, 2, and 3 still do not solve your problem, you may have to reinstall Blender.