Does Blender bloat unnecessarily the Windows Registry?
If you are unsure about entrys in the registry and want to keep your system clean, you can take the portable version.
Extract to a folder of your choice and pin to startmenu or what ever.

I personally dont use Blender installer at all, i use the portable every time and when there is a new build i override the folder content and have the new version.
If you have multiple versions you can have different folders.