Twisted IK handles. mesh is twisted. what am I doing wrong?
Instead of giving a Copy Rotation constraint to your feet, you could parent them to the IK controllers in Edit mode. But if you want to keep the Copy Rotation for some reason, choose the Z axis and Space &gt; Local Space/Local Space.

In Edit mode, bend the knees a bit forward so that Blender knows in what direction to bend them.

In Pose mode, select the lower legs and in the IK constraint, change their Angle to 180°.

I'm not sure about the spine orientation, it would probably be better if you switched the bones direction, they should point upwards.

It's better to create a root bone, parent the first spine, the controller and the target bones to it.