Is there a way to lock the topology in edit mode?
I'm using ManualBastioniLab too, and do the same accidental thing, grr. Right now my fastest solution is to delete it, start a new avatar, and import the backup json file (there's a plugin somewhere  - I can't remember where I got it, google to find it). Not a perfect solution, because I've usually just fixed the overlapping UVs that ManualBastioniLab creates and will need to do it over, but it's faster than trying to repair the broken topology.