Fluid running into invisible wall
Invisible wall? Are you sure it isn't just the fluid domain?

Check your other layers. It's possible one of them has an object in it that is interacting across multiple layers and influencing your fluid sim even though it's not on the same layer.

Also try pressing alt h to unhide all objects. Try setting the obstacle to volume only. Test these out by baking at a low res so you know it would work with a higher res.