How to port a smoke simulation folder over to the render farm?
Render farms will take your .blend file and simulate it on their own site first, to generate the Cache folder. After that, the farm activates the distribute to render-per-machine (buckets assigned) from this file using path relative cache folder. This is how you get sequentially correct simulations on a render farm. It will involve human setup on the render farm.

Useful for hair, fractures, liquid. 
Caching in Blender can take many hours or some seconds depending on the SIZE of your scene (yes, blender units to Meters..etc..) so make sure you are working with the right proportion and scale.