How to deform (randomize) object so it would look different?
Add a Lattice Object and set its resolution for your requirements. 


Select your Tooth and add the Lattice Modifier, select your Lattice.


You can now edit the Lattice vertices and deform the Tooth.

Feel free to add additional Lattices and have the deformations compound.

You will have to investigate how best to do all this in Python, but hopefully this gets you started.