Make the movemouse event back to left when get to the edge of right
I got it...
add this bl_option to the operator class can make it
bl_options = {'REGISTER', 'GRAB_CURSOR', 'BLOCKING', 'UNDO'} 
# GRAB_CURSOR + BLOCKING enables wrap-around mouse feature.

and then fix the mouse event by using mouse_x
if event.type == 'MOUSEMOVE':
    self.mouseDX = self.mouseDX - event.mouse_x
    multiplier = 0.005 if event.shift else 0.02
    # multi offset
    offset = self.mouseDX
    obj.Rad -=  offset * multiplier
    # reset
    self.mouseDX = event.mouse_x
   
```