Slow Playback of mocap data
I found I could work around my issue by optimizing a few things. I want to stress that these are all to lighten the load of the CPU during playback and I have not found any way to make Blender's playback as reliably smooth as Mixamo's web player or Maya. I suspect this issue stems from how Blender's code handles hardware acceleration during playback. Something that would be far outside of my realm of expertise.

OPTIMIZING:

Models -- 


Merged Unconnected overlapping Faces(Merge by distance)
Remove Doubles
Tris to Quads
Apply Decimate modifier for a low res proxy model.
Erase nonessential faces from low poly proxy model


Viewport: 


Use WorkBench
Shade Single if possible


Ui:


Remove as many panels as possible, this includes N and T menus.
Ctrl+alt+space to fullscreen for smoothest playback


Misc:


remove any VSE Preview panels

1a. If you need a vse preview panel, set it to the lowest resolution proxy settings


In Solid mode, with these changes I was able to go from 7 fps to 45 fps with my single character 
In Eevee the difference was from 2fps to 14fps for the same scene.

Not a perfect solution but certainly a significant performance improvement, especially in solid mode.