N Panel (Location & Rotation Boxes are YELLOW) ... Makes my Mesh Load up in the Blend file in a new location with different scale
XD you animated the mesh. The boxes turn yellow when you animated something. Do you see that yellow line in the Timeline? That means that you animated the mesh to a new location from Frame 1, all the way to the yellow line!
Delete animation of object 
Here is how to get rid of the yellow line, which would get rid of the animation. :D