How to obtain hydrophobic Doxorubicin from its hydrochloride salt?
Add a base to an aqueous solution of the compound.  The base could be ammonia water or ammonium hydroxide.  Make sure you add enough base to raise the pH to 12 or higher.
Add a water-immiscible organic solvent with a low boiling point to the solution and mix well.  A good solvent might be dichloromethane.
Let the phases separate and carefully remove the organic phase.  (If you use dichloromethane, the organic phase will be the bottom phase, but this is not true of all solvents.)
Repeat step 2 several times, each time combining the newest organic extract phase with the extract from the previous steps.
Evaporate the solvent under air, or, if you have it, an inert gas such as nitrogen.