What is the reaction rate constant of an effective reaction?
It is not clear that they are related. It is simpler to consider the equivalent scheme $A \rightarrow C \rightarrow E$ with rate constnats $k_1,\, k_2$ then the decay of A is 
$A_t/A_0= \exp(-k_1t)$ the amount of  C rises and falls; it is 
$$\displaystyle C_t/A_0 = \frac{k_1}{k_2-k_1}(\exp(-k_1t)-\exp(-k_2t))$$ and 
E is 
$$E/A_0 = 1-A_t-C_t=1-\exp(-k_1t)-\frac{k_1}{k_2-k_1}(\exp(-k_1t)-\exp(-k_2t))$$

When $k_2 $ is very large and much bigger than $k_1$ then $\exp(-k_2t) \rightarrow 0 $ and $\displaystyle E/A_0= 1-(1+\frac{k_1}{k_2})\exp(-k_1t)$ and in the opposite limit $k_1 \gg k_2$ then $E/A_0= 1-\exp(-k_2t)$.

So you can choose which limit is important. In either case the amount of E rises as time proceeds but with different rate constants. In the intermediate case there seems to be no rate constant but only a slope to the curve which will depend on the time at which the measurement in made. You could for example find the half rise time and try to relate that to rate constants, but it looks messy.