Molecular knots absolute configuration
I guess that the IUPAC Gold Book rules for helicity apply here.


  The chirality of a helical, propeller or screw-shaped molecular entity. A right-handed helix is described as P (or plus), a left-handed one as M (or minus).


The above knotane is right-handed, so it should be P.

For more complex molecular knots such simple rules most likely will fail.