Vacuum good inside a box?
Let's imagine that your transport box has a decently closing lid. It you place the herbs in the box, close the lid , stuff the box into a vacuum sealer bag, remove the air from the bag until it is shrunk around the box and finally seal it, you may consider it sealed. 

This means:


According to "household standards", it is air-tight to the outside. No air from the environment will enter the bag, unless it is damaged.
There is however still air in the box. Whatever degradation, loss of flavour, etc. may happen to the herbs during transport still can, since there is oxygen.


However, if you vaccum-seal the box, or replace the air in the box with nitrogen, you will minimize (or fully prevent) degradation of the herbs.