Constant Pressure and Temperature during Phase Change
For a pure substance, the phase rule implies that at coexistence of two phases only one intensive variable (pressure or temperature) can be altered independently, the other being dependent on the choice of the independent variable. So the answer is yes and no, you can choose to alter one of the two intensive variables and still retain two-phase equilibrium, but the choice of one intensive variable determines the value of the other. This fundamental principle derives from the conditions of thermodynamic equilibrium necessary for coexistence of the two phases. The set of $(p,T)$ points on the coexistence line can be described in terms of the Clapeyron equation $dp/dT = \Delta S/\Delta V$ and a single reference point $(p_{ref},T_{ref})$ on the line. 

Consider a pure substance in a diathermal container whose volume we can alter at will, and kept at a fixed temperature. Assume we begin with the container completely filled with a condensed phase (say liquid) of the substance, that is, the volume is too small (or alternately, the pressure too high) to allow vapor to form. We have however chosen a temperature that corresponds to a point on the coexistence line at a lower pressure (or greater volume) than that currently in the vessel. You can bring the substance to an equilibrium between two phases by changing the volume until the pressure in the container equals the equilibrium vapour pressure - a fixed pressure at that temperature. You can then continue to change the volume (all the while keeping the temperature constant). The proportion of the two phases (their volumes) will readjust to accommodate the new total volume, with heat exchanging with the surroundings to keep the temperature constant, and the pressure returning to the value at equilibrium - the same vapour pressure - provided the volume change is not too big. Naturally if you increase or decrease the volume too much you will end up with a single phase and a different pressure below or above the vapour pressure. 

Remember: you don't have to have two phases. But if you want to observe coexistence at a chosen temperature, you have no choice wrt the pressure that will ensure coexistence. What's cool is that the proportions of the two phases can be altered within a certain limited range of total volume so that p and T remain constant. I recommend consulting a p-V-T phase diagram and inspecting it carefully to see this graphically. The following is a slice in the p-V dimensions which I borrowed from this site: