Is it possible to disable the splash screen of ChemDraw?
I assume the question seeks out for a way to use ChemDraw more quickly, for example while being confronted with a larger number of chemical structures already generated, and to be processed further.  Then


If it is to browse through a number of structures aiming "to find the right file", to gain an overview, then Thumbfish (Windows only) may be helpful.  Chemdoodle (Win/Mac/Linux) and MarvinSketch offer in their file-open menu a preview as well.
On the other hand, provided the extensive documentation especially of ChemDraw seconds native, the *.cdxml format, the (batchwise) conversion into other formats is easily done with OpenBabel (supported file formats) and Apple Script ChemBot (application here).