Effects of Ionizing a Radioactive Isotope
There is no effect. Imagine you are demolishing a building with high explosives; does it matter whether the small window on the third floor was open or closed prior to the explosion? No, it doesn't. The building will go crashing down all the same.

I believe this is a correct metaphor of the relation between chemistry and radioactivity. Of course the product will be ionized. Quite probably, it will be multiply ionized via Auger events, and also will certainly ionize quite a few other atoms around. Whether it was ionized before is about as unimportant as that small window on the third floor.