Where do I start? I have a massive dataset (from web scraping) and want to predict y from 20 variables
Since you are really new to all this, here are some suggestions.

Download and install R and RStudio Desktop.

Look at the book "Introduction to Statistical Learning". The book comes with code examples (in R) which are ideal to start learning. For you it will be useful to have a look at Chapter 2 to understand what statistical learning is all about and also to get a good idea of how to use R. 

However, what is really relevant for you is Chapter 3 (linear regression) and Chapter 7 (moving beyond linearity).

Now you can get started. Here are some examples how regression can be done in R:

# Install a package if needed
# install.packages("ISLR")

# Lead packages
library(ISLR)
library(gam)
library(Metrics)

# Look at data
head(mtcars)
# Look at one variable in our dataframe
summary(mtcars$mpg)

# Make a test/train split
set.seed(123)
smp_size &lt;- floor(0.75 * nrow(mtcars))
train_ind &lt;- sample(seq_len(nrow(mtcars)), size = smp_size)
train &lt;- mtcars[train_ind, ]
test &lt;- mtcars[-train_ind, ]

# Linear regression
# Estimate mpg (y) dependent on ...
reg1 = lm(mpg~disp+wt+qsec+hp, data=train)
summary(reg1)

# Regression with polinomials
reg2 = lm(mpg~poly(disp,2)+poly(wt,2)+poly(qsec,2)+poly(hp,2), data=train)
summary(reg2)

# Generalised additive models (regression splines)
reg3 = gam(mpg~s(disp,3)+s(wt,3)+s(qsec,3)+s(hp,3),data=train)
par(mfrow=c(2,2))
plot(reg3)

# Predict mpg
pred1 = predict(reg1, newdata=test)
pred2 = predict(reg2, newdata=test)
pred3 = predict(reg3, newdata=test)

# See how well our model fits
mae(test$mpg, pred1)
mae(test$mpg, pred2)
mae(test$mpg, pred3)