Clashes when combining openGL and GUI
General answer is that creating a window as a GUI element with some GUI designer library involves subclassing some basic GUI element (like widget in QtCreator for example) with class providing handling GL context in more or less user friendly way (like QOpenGLWidget in QtCreator which provide some user friendly wrapper or on the other hand basic Win32 API handle) and override methods for handling its framebuffer drawing or resizing, swapping buffers etc. with usual gl extensions provided by some lib you use.

This will work perfectly fine with other GUI elements.

I don't know which GUI lib or IDE with GUI designer or language you prefer but most good libs can handle this. You can even do it in Assembler with WinApi GUI elements.