Nginx Vhost Config - Get page based on translated URI and without parameters in url
Ok, I got it working with:

nginx vhost config:

location /en/ {
    try_files $uri $uri/ @enrewrites;
}

location /nl/ {
    try_files $uri $uri/ @nlrewrites;
}

location / {
    try_files $uri $uri/ @rewrites;
}

location @enrewrites {
    rewrite ^/en/(.*)$ /en/index.php?p=$1 last;
}

location @nlrewrites {
    rewrite ^/nl/(.*)$ /nl/index.php?p=$1 last;
}

location @rewrites {
    rewrite ^(.*) /index.php?p=$1 last;
}


And in general craft config:

'omitScriptNameInUrls' =&gt; true,