After months of speculation and rumors that Johnny Depp and his longtime partner and mother of his two children, Vanessa Paradis, were on the outs, Depp's rep has confirmed their separation. 
 
 "Johnny Depp and Vanessa Paradis have amicably separated," the rep told Entertainment Tonight on Tuesday. "Please respect their privacy and, more importantly, the privacy of their children." 
 
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 Depp, 49, and Paradis, 39, have been together since 1998, an eternity by Hollywood standards. Depp took up with Paradis shortly after parting ways with supermodel Kate Moss. 
 
 Depp and Paradis had a daughter, Lily-Rose, in 1999, and a son, John, in 2002. 
 
 READ: Depp and Paradis living separate lives. 
 
 When Depp and Paradis met, he was mostly known for quirky parts in Tim Burton movies. Today, he is one of the highest paid, and richest, actors in the world thanks to the "Pirates of the Caribbean" franchise in which he stars. ||||| Vince Bucci/ Getty Images 
 
 Just in to Entertainment Tonight exclusively from Johnny Depp's publicist: 
 
 "Johnny Depp and Vanessa Paradis have amicably separated. Please respect their privacy and, more importantly, the privacy of their children." 
 
 PICS: Star Sightings 
 
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– Deny, deny, confirm: Johnny Depp's publicist has verified to Entertainment Tonight that the actor has indeed split with Vanessa Paradis. The statement is short, typical, and a tiny bit heart-wrenching: "Johnny Depp and Vanessa Paradis have amicably separated. Please respect their privacy and, more importantly, the privacy of their children." Depp, 49, and Paradis, 39, have been together since 1998, notes Fox News. They have two children together.