data is used by pharma- ceutical industries for the research and development of drugs and medical devices. Doctors monitor and diagnose individual patients from the temporal data. The patient 5G Wireless Communication System in Healthcare Informatics data can be retrieved by an eavesdropper in the communication channel or from device storage. So, security of patient data is very essential in H-IoT. Several crypto- graphic algorithms have been reported in the literature [24-27]. Cryptography is a current encryption technology that comprises of several mathematical operations. It was originally developed to protect the confidentiality of diplomatic and mili- tary communications [28]. Cryptography is described as "the branch of cryptology concerned with the development of encryption and decryption methods to ensure the security and authentication of data". Encryption and decryption are the most basic functions of cryptography [28]. Encryption refers to a conversion process whereby plain text is processed and converted into secured and coded text SO that it is difficult for an unauthorised party to recover the actual message whereas decryption is a pro- cess whereby ciphertext (coded text) is turned into the original text. Both features are used to protect messages from being viewed by people who aren't authorised to see them [29, 30]. Blockchain technology is used for crypto-security, and for transparent and secure data networks [7]. With healthcare 4.0 and blockchain 3.0 data network processes, a smart healthcare system has been designed and implemented. The various healthcare 4.0 processes are IoT, industrial IoT, cloud, cognitive, artificial intelligence, quantum computing, fog, and edge computing, and the like. Optimized algorithms are implemented on healthcare 4.0 technologies along with the secure blockchain decentralized data network. Ahmad F. Subahi [31] proposed the architecture, design, and recommendation for an edge based IoT healthcare management system. There is redistribution of work- load between two 