This study begins using a 2.75 GHz design of microstrip antenna and progresses to a four-port MIMO antenna with no parallel slotted lines. The design and testing for a 4-Port MIMO antenna having a parallel slotted line between the pair of antennas are then planned, followed by a model of octagonal-shaped port construction [18-23]. All electromagnetic models and designs were approved using Ansys HFSS, a tool used in the simulation of three dimensional (3D) electromagnetics for high frequency constituents. Ansys HFSS uses a finite element method (FEM) to analyze HF (high frequency) devices such as antennas quickly and accurately. The suggested 4 PORT MIMO antenna has the following advantages and improvements [24-31]: Simplicity: This framework is straightforward. It was designed and manufactured with low losses upon thin FR4-Epoxy substrate. It reduces the MIMO Antennas for loT and ISM Band complexity of systems, making it simple to integrate into a number of com- munication systems. Miniaturization: By decreasing mutual coupling between the ports using a hybrid technique, the planned construction delivers higher performance in the industrial, scientific, and medical (ISM) frequency range in a compact size of (40 X 80 X 1.6mm³. 3. Virtual reflection coefficient: The coefficient of reflection of the projected antenna being lesser than 1 dB over the whole frequency range. This coeffi- cient shows that the impedance matching is better, and hence the power of radiation is sufficient. Less mutual coupling: Over the full frequency or bandwidth range, the two sections achieve good isolation greater than db. To accommodate a four- port MIMO antenna array into a tiny space, a multiple-parallel lines isolating device and a split octagonal ring resonator are used. ISM band application: Electromagnetic interference is caused by the use of ISM equipment, which affects radio communications on the same frequency. As a result, this technique was restricted to a few frequency bands. Users have little influence over how ISM equipmen