ance-dependent path loss, shadowing, and implementation loss. The uplink power control takes into consideration the MIMO transmission mode, and whether a single user or multiple users are supported on the same resource at the same time. The open-loop power control compensates for the channel variations and implementation loss without requiring frequent interac- tions with the serving BS. The MS can determine the transmit power based on the transmission parameters sent by the BS, uplink channel quality, downlink channel state information, or the inter- ference knowledge obtained from downlink transmissions. The open-loop power control provides a coarse initial transmit power setting for the mobile station before establishing connection with the base station. A power control mechanism takes into consideration the serving BS link target SINR and/or interference level to other cells/sectors for mitigating inter-cell interference. In order to achieve the target SINR, the serving BS path-loss can be fully or partially compensated based on a trade-off between overall system throughput and cell edge performance. The mobile station's transmit power is adjusted in order to ensure the level of interference is less than the permissible interference level. The compensation factor and interference targets for each frequency partition are determined and broadcast by the serving BS considering the FFR pattern, cell loading, etc. The closed-loop power control, on the other hand, compensates channel variations through periodic power-control commands from the serving BS. The base station measures the uplink channel state information and interference level using uplink data and/ or control channel transmissions, and sends power control commands to the mobile stations. On receiving the power control command from the serving BS, the MS adjusts its uplink transmit power. The closed-loop power control is active during data and control channel transmissions. An MS is expected to maintain the transmit power density (i.e., total transmit p