t is utilized since, in general, commu- nication equipment operating in these bands should be able to withstand the interference created by ISM equipment. 6. Novelty: Combining an innovative technique, a multi-parallel line isolating element, CSRR and SRR were used in this paper for improving impedance matching, isolation, bandwidth, and for creating two innovative mechanisms using frequency band rejection, which is utilized for resolving electromag- netic interferences having two major applications with the involvement of the IoT and the ISM band range. 11.2 ANTENNA DESIGN The geometry for a proposed 4-Port MIMO antenna having two frequency rejection characteristics is shown in Figure 11.1. To provide a broad frequency response, design procedure begins with the fabri- cation of a four-port MIMO antenna having four symmetrical octagonal patches and a modified plane with partial ground. A four-line stub has been inserted at the plane with an upper ground over the entire bandwidth to improve bandwidth, impedance matching, isolation in-between the pair of elements of two antenna. To acquire our results within range of frequency of 2.25-3.0GHz, CSRR has been imprinted upon the patch elements, and at the same time a SRR been loaded upon ground plane upon rear of every radiation element. The proposed structure was built on FR4-epoxy sub- strate having thickness equal to 1.6 mm, with E (dielectric constant) equal to 4.4, tan- gent loss (8) equal to 0.0023. The physical dimensions of the proposed 4-Port MIMO antenna, having the small size of 40x80mm², are listed in Table 11.1. Parameters Values (mm) 5G Wireless Communication System in Healthcare Informatics FIGURE 11.1 (a) Front part of the antenna, (b) Back part of the antenna. 11.3 EVOLUTION OF THE DESIGN OF COMPACT 4-PORT MIMO ANTENNAS The design development of the intended Compact 4-Port MIMO antenna element is shown. The design process begins with the fabrication of an ISM band MIMO antenna using a modified partial ground plane and a traditional octagonal patch. The