Mona Lisa ( also known as La Gioconda or La Joconde ) is a 16th-century portrait painted in oil by Leonardo da Vinci during the Renaissance in Florence , Italy . Mona Lisa ( also known as La Gioconda or La Joconde ) is a 16th-century portrait painted in oil on a poplar panel by Leonardo di ser Piero da Vinci during the Renaissance in Florence , Italy .