William & Mary educated U.S. Presidents Thomas Jefferson , James Monroe , and John Tyler as well as other key figures important to the development of the nation , including U.S. Supreme Court Chief Justice John Marshall , Speaker of the House Henry Clay and 16 signers of the Declaration of Independence . William & Mary educated U.S. Presidents Thomas Jefferson , James Monroe , and John Tyler as well as other key figures important to the development of the nation , including U.S. Supreme Court Chief Justice John Marshall , Speaker of the House Henry Clay , and 16 signers of the Declaration of Independence .