In 2001 , the Santo Domingo Province was created with much of the area of the old Distrito Nacional ( `` National District '' ) . With that division , many parts of the old city are now part of the Santo Domingo Province and not of the city of Santo Domingo de GuzmÃ n. But they are still part of the metropolitan area of the city ( the Greater Santo Domingo ) . Please note : When this article refers to Santo Domingo it is most likely referring to the Greater Santo Domingo Area ( Distrito Nacional plus Santo Domingo Province ) .