Louisa Catherine Johnson Adams ( February 12 , 1775 â `` May 15 , 1852 ) was the wife of US President John Quincy Adams . As the wife of the US President , she was the First Lady of the United States from 1825 to 1829 . Louisa Catherine Johnson Adams , born Louisa Catherine Johnson ( February 12 , 1775 -- May 15 , 1852 ) , wife of John Quincy Adams , was First Lady of the United States from 1825 to 1829 .