Vasoactive intestinal peptide ( VIP , also polypeptide ) is a kind of hormone that has 28 amino acid residues in it and is made in many areas of the human body including the gut , pancreas , and suprachiasmatic nuclei ( which is a small part of the brain 's midline ) of the hypothalamus in the brain . Vasoactive intestinal peptide ( VIP , also polypeptide ) is a peptide hormone containing 28 amino acid residues and is produced in many areas of the human body including the gut , pancreas and suprachiasmatic nuclei of the hypothalamus in the brain .