It was founded by the name Villa de SantafÃ in 1541 by Jorge Robledo on the western bank of the Cauca River . It received the coat of arms and the title of City of Antioquia from King Philip II of Spain in 1545 . Founded in 1541 by Jorge Robledo as Villa de SantafÃ on the western bank of the Cauca River , in 1545 it received the coat of arms and the title of City of Antioquia from King Philip II of Spain .