Sydney Brenner CH FRS ( born 13 January 1927 ) is a South African biologist and a 2002 Nobel Prize in Physiology or Medicine laureate , shared with Robert Horvitz and John Sulston . Sydney Brenner , CH FRS ( born January 13 , 1927 ) is a South African biologist and a 2002 Nobel prize in Physiology or Medicine laureate , shared with H. Robert Horvitz and John Sulston .