He moved with his wife Harriet to Cold Spring Harbor , New York , in 1950 to join the Carnegie Institution of Washington 's Department of Genetics . There he performed the famous Hershey-Chase blender experiment with Martha Chase in 1952 . He moved with his wife Harriet to Cold Spring Harbor , New York , in 1950 to join the Carnegie Institution of Washington 's Department of Genetics , where he performed the famous Hershey-Chase blender experiment with Martha Chase in 1952 .