U.S. Route 163 , U.S. Route 400 , U.S. Route 412 , and U.S. Route 425 have 3-digit numbers that do not act as a spur of a 1 or 2 digit route . In addition , U.S. Route 163 , designated in 1970 , is nowhere near U.S. Route 63 . The short U.S. Route 57 , approved ca .