Laura Bush ( born Laura Lane Welch on November 4 , 1946 in Midland , Texas ) was the First Lady ( The President 's Wife ) of the United States from 2001 to 2009 . She is the wife of George W. Bush , who was the President then . Laura Lane Welch Bush ( born November 4 , 1946 ) is the wife of the 43rd President of the United States , George W. Bush .