Maria lies 32 kilometers northeast of Manila and is located at the eastern portion of Bulacan . The town is bounded on the north by the municipalities of Angat and Pandi , portion of San Jose del Monte City on the south ; Norzagaray and other portions of San Jose del Monte on the east ; and the municipality of Marilao and Bocaue on the western side . Today , Santa Maria 's position as a growth center in the eastern portion of Bulacan covering the most densely populated City of San Jose del Monte and the municipalities of Norzagaray , Marilao , Bocaue , Angat , Pandi , and Dona Remedios Trinidad ( pop .