The University of Manchester is a university in Manchester , England . In 2007-08 , it had over 40,000 students studying 500 academic programs , and more than 10,000 staff and an annual income of Â # 637 million . In 2007\/08 , the University of Manchester had over 40,000 students studying 500 academic programs and more than 10,000 staff , making it the largest single-site university in the United Kingdom .