Biloxi is coâ `` county seat with the larger city Gulfport , in the Gulfport-Biloxi , Mississippi Metropolitan Statistical Area , which is included in the Gulfport-Biloxi-Pascagoula , Mississippi Combined Statistical Area . The city is part of the Gulfport-Biloxi metropolitan area and the Gulfport-Biloxi-Pascagoula , Mississippi Combined Statistical Area .