The Princess Alice ( Alice Maud Mary : Princess Louis and Grand Duchess of Hesse and by Rhine by marriage ; April 25 , 1843 â `` December 14 , 1878 ) was the second daughter of Queen Victoria and Prince Albert . The Princess Alice ( Alice Maud Mary : Princess Louis and Grand Duchess of Hesse and by Rhine by marriage ; 25 April 1843 â `` 14 December 1878 ) was a member of the British royal family , the third child and second daughter of Queen Victoria and Prince Albert of Saxe-Coburg and Gotha .