Over 430,000 inhabitants live in the Greater Metropolitan Area of Coimbra . Over 430,000 people live in the Greater Metropolitan Area of Coimbra , comprising 16 municipalities and extending into an area 3,372 kmÂ . Coimbra is one of the most important urban centres in Portugal ( after the much larger Lisbon Metropolitan Area and Porto Metropolitan Area ) , playing a central role in the interior of the country .