Amfissa is a Greek city . In that period , Plutarch mentions , in the work Parallel Lives , a physician from Amfissa named Philotas ( Marcus Antonius 28 ) . During the 2nd century , Amfissa was a prosperous town which expanded outside its walls , having a population of 70,000 people in 180 BC according to Pausanias , while during the reign of Diocletian , Amfissa is said to have a splendid aqueduct .