La Penne-sur-Huveaune is a commune of 6,150 people ( 2008 ) . It is found in the region Provence-Alpes-C Ã te d'Azur in the Bouches-du-Rh Ã ne department in the south of France . La Penne-sur-Huveaune is a commune east of Marseille and west of Aubagne along the A50 autoroute in the department of Bouches-du-Rh Ã ne in the Provence-Alpes-C Ã te d'Azur region in southern France .