The advantage of oral pseudoephedrine over topical nasal preparations , such as oxymetazoline , is that it does not cause rebound congestion ( rhinitis medicamentosa ) ; however , it is more likely to cause adverse effects including high blood pressure . The advantage of oral pseudoephedrine over topical nasal preparations , such as oxymetazoline , is that it does not cause rebound congestion ( rhinitis medicamentosa ) .