Vino Nobile di Montepulciano ( in English lit . Noble Wine of Montepulciano ) is a red wine with Denominazione di Origine Controllata e Garantita status produced in the vineyards in the town of Montepulciano , Tuscany , Italy . Vino Nobile di Montepulciano is a red wine with Denominazione di Origine Controllata e Garantita status produced in the vineyards surrounding the town of Montepulciano , Italy .