Klug won the 1982 Nobel Prize in Chemistry for developing crystallographic electron microscopy and working out the structure of nucleic acid-protein complexes . Sir Aaron Klug , OM , PRS ( born 11 August 1926 ) is a Lithuanian-born British chemist and biophysicist , and winner of the 1982 Nobel Prize in Chemistry for his development of crystallographic electron microscopy and his structural elucidation of biologically important nucleic acid-protein complexes .