Malcolm in the Middle was a 2000 Fox television series that ran from January 9 , 2000 to May 14 , 2006 . Malcolm in the Middle is an American comedy television series created by Linwood Boomer for the Fox Network . The series was first broadcast on January 9 , 2000 , and ended its six-and-a-half-year run on May 14 , 2006 , after seven seasons and 151 episodes .