Asperger syndrome is considered to be at the highest functioning end of the Autism spectrum disorders . Both genders can have Asperger syndrome , although it is more common in males . The diagnosis of AS is complicated by the use of several different screening instruments , including the Asperger Syndrome Diagnostic Scale ( ASDS ) , Autism Spectrum Screening Questionnaire ( ASSQ ) , Childhood Asperger Syndrome Test ( CAST ) , Gilliam Asperger 's Disorder Scale ( GADS ) , Krug Asperger 's Disorder Index ( KADI ) , and the Autism Spectrum Quotient ( AQ ; with versions for children , adolescents and adults ) .