The site where the PLM campus at Intramuros is situated used to be occupied by the Colegio de Manila ( also known as Colegio Seminario de San Ignacio ) , which was founded in 1590 by Fr . The site where the PLM campus at Intramuros is situated used to be occupied by the Colegio de Manila ( also known as Colegio Seminario de San Ignacio , later Universidad Maximo de San Ignacio , the first royal and pontifical university in the Philippines and in Asia ) , which was the first school in the Philippines .