U.S. Route 1 ( sometimes called US 1 ) is a major United States highway ( U.S. Route ) in the eastern part of the United States . In all states but Georgia that had numbered their state highways , Route 1 followed only one or two numbers across the state . The only significant deviation from the Atlantic Highway was between Augusta , Georgia and Jacksonville , Florida , where Route 1 was assigned to a more inland route , rather than following the Atlantic Highway via Savannah .