Lindsay ( played by Ashley C. Williams ) and Jenny ( played by Ashlynn Yennie ) are two American girls who are on holiday in Germany . They are kidnapped by a mad doctor called Dr. Heiter ( played by Dieter Laser ) after their car breaks down and they go to his house to look for help . Lindsay ( Ashley C. Williams ) and Jenny ( Ashlynn Yennie ) , two American tourists in Germany , are drugged and kidnapped by crazed surgeon Dr. Heiter ( Dieter Laser ) when they seek help after their car breaks down .