Below is an context that describes a sql query, paired with an question that provides further information. Write an answer that appropriately completes the request.  # noqa: E501
### Context:
CREATE TABLE table_name_46 (lost INTEGER, team VARCHAR, points VARCHAR)
### Question:
What is the lowest Lost for são paulo railway, Points more than 21?
### Answer:
SELECT MIN(lost) FROM table_name_46 WHERE team = "são paulo railway" AND points > 21