Below is an context that describes a sql query, paired with an question that provides further information. Write an answer that appropriately completes the request.  # noqa: E501
### Context:
CREATE TABLE table_16028459_2 (game INTEGER, bills_first_downs VARCHAR)
### Question:
When is the latest game the bills had 21 first downs
### Answer:
SELECT MIN(game) FROM table_16028459_2 WHERE bills_first_downs = 21