Below is an context that describes a sql query, paired with an question that provides further information. Write an answer that appropriately completes the request.  # noqa: E501
### Context:
CREATE TABLE medicine_enzyme_interaction (id VARCHAR, enzyme_id VARCHAR); CREATE TABLE enzyme (id VARCHAR, enzyme_id VARCHAR)
### Question:
How many enzymes do not have any interactions?
### Answer:
SELECT COUNT(*) FROM enzyme WHERE NOT id IN (SELECT enzyme_id FROM medicine_enzyme_interaction)