text: Below is an context that describes a sql query, paired with an question that provides further information. Write an answer that appropriately completes the request.  # noqa: E501
  ### Context:
  CREATE TABLE medicine (name VARCHAR, trade_name VARCHAR); CREATE TABLE medicine_enzyme_interaction (medicine_id VARCHAR, enzyme_id VARCHAR); CREATE TABLE medicine (name VARCHAR, trade_name VARCHAR, id VARCHAR); CREATE TABLE enzyme (id VARCHAR, product VARCHAR)
  ### Question:
  Show the medicine names and trade names that cannot interact with the enzyme with product 'Heme'.
  ### Answer:
  SELECT name, trade_name FROM medicine EXCEPT SELECT T1.name, T1.trade_name FROM medicine AS T1 JOIN medicine_enzyme_interaction AS T2 ON T2.medicine_id = T1.id JOIN enzyme AS T3 ON T3.id = T2.enzyme_id WHERE T3.product = 'Protoporphyrinogen IX'