Backer Jonachan Princizal Investigalor'P oniam Director (Last firsi mijalel" BIOGRAPHICAL SKETCH follo xing information lor kcy Personne Form Page Piovide Ine Ie Drde Hlisted Page Or follov this forma: Fhcacopt eaci Veison NAME TITLE posiion James W, Mcllroy Research Associate EOUCATION (Begin Kia Jercanennaan olncr Irhldl prolOSsiola} aducalicn Such TIV SD uridTTCILOC DosicOC Ctanta DEGAIE OCATION INSMTUTIONAND YEAP FifiD OF STUdY apOJcauia Queens University, Belfast; N. Ireland Biochemistry B.Sc. 1991 University of Ulster, N. Ireland MBA 1992 Bus Admin: Biochemistry Queens University, Belfast; N. Ireland PhD 995 Albert Einstein College of Medicine Bronx; NY Post 1995- Mol: Pharmacol: RESEARCH AND PROFESSIONAL FXPERIENCE Concluding Dresent posucn cnrcnooncal order pieviows emblaimcni Wroctnncr Goverineni public advisory commiitee and nonois cludc prcsomi Membetship any Federa ordcn, the fles; chromolchica Juthols publica; zns during complee ree ence: (nc past miee vears and replesemal Garle Plol the Iist Icaricne Denicen appucaliom publcatins exceeds tao pages se ect the most pernent publicatipns DO NOT EXCEED TWO PAGES. ast Inccc voars Publications Kay Nelson; J. Duffey; Mcllroy, Cullen Graeme and Walker, B (1993) novel trypsin-like enzyme associated with breast cancer. Brit. Cancer, 6Z, 152. Mcllroy, Kay,G Nelson; Cullen; Walker, B. (1993) A novel trypsin-like enzyme in human and Trans 22, 19S breast tissue. Biochem: Soc. Oadling Smee, W: Kay, Mcllroy, Nelson; J. Cullen Lynas Spence R and Walker, B (1994) A novel trypsin-like enzyme in breast cancer: J. Cell. Biochem 18D, S221 Yan; Mcllroy, Lynas Murphy, Walker, B. and Yee, (1995) The application of novel synthetic protease inhibitors for the disclosure and partial characterisation of cathepsin LIS-like protease produced by OSPR osteosarcoma cells in cullure and their utilisation in the prevention of J.Cell: Biochem: 19B invasion; B1-213. Chen D, Wjasow, C, Mcllroy, Michaeli; T. and Backer; J.M (1996) Specific activation of p85/p110 PI 3'-kinase stimulates DNA synthesis by Ras-dependent pathway Mol: Cell: Biol. (in press): PHS 398 (Re. 4/95 (Ferm Page 6) Page Numboc pajes cOrsecj: X y 8: lne eeilom Ihr_lstiolt Int #Fplc" Jn nollic nuc< suzh & 37 50658428
Princizal Investigalor'P oniam Backer Jonachan Director (Last firsi mijalel" BIOGRAPHICAL SKETCH Piovide Ine follo xing information lor kcy Personne Ie Drde Hlisted Form Page Fhcacopt Page Or follov this forma: eaci Veison NAME posiion TITLE James W, Mcllroy Research Associate EOUCATION (Begin Kia Jercanennaan olncr Irhldl prolOSsiola} aducalicn Such TIV SD uridTTCILOC DosicOC Ctanta DEGAIE INSMTUTIONAND OCATION apOJcauia YEAP FifiD OF STUdY Queens University, Belfast; N. Ireland B.Sc. 1991 Biochemistry University of Ulster, N. Ireland MBA 1992 Bus Admin: Queens University, Belfast; N. Ireland PhD 995 Biochemistry Albert Einstein College of Medicine Bronx; NY Post 1995- Mol: Pharmacol: RESEARCH AND PROFESSIONAL FXPERIENCE Concluding Dresent posucn cnrcnooncal order pieviows emblaimcni Wroctnncr and nonois cludc prcsomi Membetship any Federa Goverineni public advisory commiitee chromolchica ordcn, the fles; Juthols complee ree ence: publica; zns during (nc past miee vears and replesemal Garle Plol Icaricne Denicen appucaliom the Iist publcatins ast Inccc voars exceeds tao pages se ect the most pernent publicatipns DO NOT EXCEED TWO PAGES. Publications Kay Cullen Graeme Nelson; J. Duffey; Mcllroy, and Walker, B (1993) novel trypsin-like enzyme associated with breast cancer. Brit. Cancer, 6Z, 152. Mcllroy, Kay,G Nelson; Cullen; and Walker, B. (1993) A novel trypsin-like enzyme in human breast tissue. Biochem: Soc. Trans 22, 19S Mcllroy, Kay, Nelson; J. Cullen Lynas Oadling Smee, W: Spence R and Walker, B (1994) A novel trypsin-like enzyme in breast cancer: J. Cell. Biochem 18D, S221 Walker, B. Yan; Mcllroy, Lynas Murphy, and Yee, (1995) The application of novel synthetic protease inhibitors for the disclosure and partial characterisation of cathepsin LIS-like protease produced by OSPR osteosarcoma cells in cullure and their utilisation in the prevention of invasion; J.Cell: Biochem: 19B B1-213. Mcllroy, Chen D, Wjasow, C, Michaeli; T. and Backer; J.M (1996) Specific activation of p85/p110 PI 3'-kinase stimulates DNA synthesis by Ras-dependent pathway Mol: Cell: Biol. (in press): PHS 398 (Re. 4/95 (Ferm Page 6) Page Numboc pajes cOrsecj: X y 8: lne eeilom Ihr_lstiolt Int #Fplc" Jn nollic nuc< suzh & 37 50658428