{ou 10;16 FAG 002 Yal J29 TOEACCO silcific LUG CARCIVOGEN VKiNE OFNONSMOKER} HECHI E7 AL TOBACCO SFECIFC LUNG CARCINOGEN IN THE URINE OF MEN EXPOSED TO CICARETTE SHOKE Stlrrl7 Hal 642MFIA, Suskok Mcrphy, ?#D PA.D_ Svly Snoena AraraR Kuu DiVNNEMAMN *,5 DIkICH Honasx, Pa.D Abutec BcOTdy Enonmemk ptu 117g Caclogan MNALFasaln HOCcC1 Bmce Tca 73 baan clulled by Enmicranul Prorecton Croiciu Todont Ajonsy cucncear eokce/0J n-h Iun} COAk The ur-ayy wodion Aeemt 1u m60cpe; clCU bI; thare nive btvn nJ npots Feun? EumO B1PORIO c& Rlmam Sdi8mn ONn BtN 4 t2 oronojant tta bod; Aka Net metdoro To maau oNNAT*- Ilen euas axoiod onshcri HrloiT Cra loba Tlca nateanant htt nr 0Sojur [1n 2 61 En2 (33,0220 dvs nope hoM2i:7n Marods Cua nonlmolcns 31141 pTcI par doni P<oooihond mis &ne JJtg Wpoioc Wicojte4n 094r0j9 EMokc De7ananeJ Mastne 4or Wair L047n ucton Promoi Tr nko In 01 rofararou dqlotas IB0 mjubaon o8c7 0f (+0 i6 concecatont ntch the mon Ro? & Mia & 5 montls WpUL 81dunmlti #crU 4c4 1c in 4en 0onomtl neab EM0a-; Gloi C hnabi Ine brckarlno 4nd ol # ciqand bo Illd bir Trvnty bu-oudno snctus hlyo Dolcd truin PudI Nonemokers coctucni Icsuoen 0 Dolcd bedm Ebuida 7n) Unna R4no0 67068 Iako Outo 4d molborr 0n0az0 cycid 4Jnchuno ncnnicot 8 Tnch anoedl-i outd; nicn povcos Crormontal Ecea  kx Lha Eroool IRLL GuJrenda - aN Mollollos anticmmMentu loecoun 4(mtynerosiniro} 1+3-pyi4 | buanona cnc_uBt 4Clce". (NIQ (El Med 1933.329.15416 } EUONNET (obac? Tole anolers; Tcsedaua, dliicd Protcction Agtn" by Inc Envicnmcal chemical atudia thar have daons niad ce (EPA) peuorr human Conjita smolcn DNA Lung: nccea Tedo' Iuchy Pxiva imoking Tddiel TcDs cwsilly conduoed: 0em uiuciied Ihe mclabolic acuvalyn NNE +ilh lung cincfr 30361 hu: LaJu; 1n8 tnvitcnnenial lobaco NKK hu imporial mle ung Ulcinducoon by the Iotal wcisbt Smiat cidelice, baloriga ciner: i Imolch In Frouia NNR avenayc clgior EPA CTFtunI Diudhcd Iy mchibclzed Althoush ANK iuallr Group Urdi d crecircgen (nomg Tnbs crelua- Jumi 25 RTCebL [crtible unE the docc Pinm d-{Cponse tcLationt 04+7 exacice Cicuicilcc codivig ALUDYI [ren Jac CPOLNG Jpoule -(mcuh Dicrosaminc)-|+(3-pyri: rcducucn prcduct cnttronmienl 4nd t ddopncul bacco EMon (MALL NMAL Gnci cn-Dulino; cIrsall Potelul ucnodutdioma pulmomr Tnere hace Rcceatl) eltnozen Fuded dem- noacircicegenic ILUTENTVI Tfudie ICbICCC Freedce these Mcuklitct DILNAC coigorucol nieiintand cilinin Inc Dlos In&ui LNi aliotcn NNAL, 4Ldy Melamtd Mtc lojmokt IcccDi Lyddo bivs Cl dusuncnide ad Lodnice metabdlite tiblih-d Qalne pFeinGe Aduck Drne uoncllobi ncnern rrolid sidananm Fimincbl phony Dladdet Ccczt Dcn- MEOrE IMT CAch DPoice cinmnaichad iblcco IMCLC this F'per, Hruons Dejcnje pIOcnce rclato- "'Pecif: [uns Cdinarcn Datrn Kencbay Stud nittcnanino) [-(3-pyrid;/)-|-butanons (MNK;,inthe Idereti Inudo etwrMo Gr i8 wta endudd und DonSmOrGT) Cidred IAstnind drclre Ie: DOLLIL Jaar Jmnoie Sccnrm Gf7deh DeiclleM36 Jinorc [ai ru{~6 MeERJcean ulcener: onai-la bron ! Ilutauft Abiat cizziile &a Tee Nokol 41d ped priocpel LOmpencat 14rz CUEE  7anna Foniuina> Ennton do Extciro Dmi Lobicco IMot anine NNK b' puwrerful pulmncnzny TC Net L17c crcinogen, inducicg PULaNn) I15e prcdomanintly adenocirarori thc lunz' 54 onnneec A4rau(ISn Jady e J Frtner hinittc? miac Ibe roule oladminis refrru Lit 14HigLo I7 Tbc krot Eh GLA [Nuom sxi4{66a1 urc; Ltakex Ukztteud dun Anduce rconieca AiLed Iag TAtAM Tinalo WFA duser Imclas yhict Iilduet3 4maktijt1g'1O Meoice, akculatcu Ucm In LitniAnLen boi u Bctc prure %ukui61 amouh Kcn Di ezarcite munuclm Mlo-rkidluc $4 m W I Jmcic HdIuzbol Ttuuicuienig mrllelite 470ot nafon_I CdkO Qute ~bk Ideacun Liate Orq retginctesgs_uee4h Watir Ranbu_ 3i 4u7-aonge {CJ7i" Aytnteteln Tou454 met onenti:fig, LaFptd 01 92- OH n04l ~1ndlf4 Nra Cuc 55a nici6# Uru6789u1n6U 56fA70 1 Cel RRIEte Fnid Kanl,
{ou 10;16 FAG 002 Yal J29 TOEACCO silcific LUG CARCIVOGEN VKiNE OFNONSMOKER} HECHI E7 AL TOBACCO SFECIFC LUNG CARCINOGEN IN THE URINE OF MEN EXPOSED TO CICARETTE SHOKE Stlrrl7 Hal PA.D_ Svly 642MFIA, Suskok Mcrphy, ?#D Snoena AraraR Kuu DiVNNEMAMN *,5 DIkICH Honasx, Pa.D Abutec BcOTdy Enonmemk HOCcC1 Bmce baan ptu 117g Caclogan Tca 73 MNALFasaln clulled by Enmicranul Prorecton Croiciu Todont Ajonsy cucncear COAk eokce/0J n-h Iun} Aeemt clCU The ur-ayy wodion Feun? 1u m60cpe; bI; thare nive btvn nJ npots EumO B1PORIO c& Rlmam oronojant Net metdoro Sdi8mn ONn BtN 4 t2 tta bod; Aka Ilen To maau euas oNNAT*- onshcri axoiod HrloiT Cra loba Tlca nateanant htt nr 0Sojur [1n 2 61 En2 (33,0220 dvs Marods Cua nope hoM2i:7n nonlmolcns Wpoioc 31141 pTcI par doni P<oooihond mis &ne JJtg Wicojte4n 094r0j9 EMokc De7ananeJ Mastne 4or Wair L047n ucton Promoi In 01 rofararou dqlotas Tr nko IB0 mjubaon o8c7 0f (+0 i6 concecatont Mia & 5 montls WpUL ntch the mon Ro? & 81dunmlti #crU 4c4 4en 0onomtl  Gloi C hnabi 1c in neab EM0a-; Ine brckarlno 4nd ol # ciqand bo Illd bir truin PudI Trvnty bu-oudno snctus hlyo Dolcd coctucni bedm Nonemokers 0 Dolcd Icsuoen Ebuida 7n) Unna R4no0 Outo 0n0az0 67068 Iako 4Jnchuno ncnnicot 4d molborr cycid IRLL Tnch anoedl-i outd; 8 nicn povcos Crormontal Ecea  kx Lha Eroool  GuJrenda - aN Mollollos anticmmMentu loecoun 4(mtynerosiniro} 1+3-pyi4 | buanona cnc_uBt 4Clce". (NIQ (El Med 1933.329.15416 } (obac? EUONNET Tole anolers; dliicd Tcsedaua, by Inc Envicnmcal Protcction Agtn" chemical atudia thar have daons niad ce (EPA) human peuorr Conjita nccea Tedo' smolcn Lung: DNA conduoed: Tddiel Iuchy Pxiva imoking TcDs cwsilly uiuciied 0em Ihe mclabolic acuvalyn +ilh lung cincfr LaJu; NNE 30361 hu: 1n8 tnvitcnnenial lobaco NKK hu Smiat imporial mle Ulcinducoon ung by the Iotal wcisbt cidelice, baloriga ciner: i Imolch In Frouia clgior NNR CTFtunI avenayc Diudhcd EPA Iy mchibclzed Group (nomg Althoush ANK iuallr Urdi d Jumi crecircgen Tnbs crelua- [crtible unE 25 RTCebL 04+7 the docc Pinm d-{Cponse tcLationt exacice Cicuicilcc codivig  [ren Jac CPOLNG ALUDYI Jpoule cnttronmienl rcducucn prcduct bacco -(mcuh Dicrosaminc)-|+(3-pyri: EMon 4nd t ddopncul Gnci cn-Dulino; cIrsall (MALL NMAL pulmomr ucnodutdioma Potelul Tnere hace eltnozen Fuded ILUTENTVI Tfudie Rcceatl) dem- noacircicegenic ICbICCC DILNAC coigorucol Freedce these Mcuklitct nieiintand cilinin Inc Dlos LNi aliotcn In&ui Mtc 4Ldy lojmokt Melamtd NNAL, IcccDi Lyddo bivs Cl dusuncnide ad Lodnice tiblih-d metabdlite pFeinGe Aduck Qalne uoncllobi Drne Fimincbl ncnern rrolid sidananm phony Dladdet Ccczt Dcn- MEOrE IMT CAch DPoice cinmnaichad iblcco IMCLC this F'per, Dejcnje pIOcnce rclato- Hruons "'Pecif: [uns Cdinarcn Kencbay Stud Datrn nittcnanino) [-(3-pyrid;/)-|-butanons (MNK;,inthe und DonSmOrGT) Cidred endudd IAstnind Idereti Inudo etwrMo Gr i8 wta drclre Jmnoie Sccnrm Ie: DOLLIL Jaar  DeiclleM36 Gf7deh Jinorc [ai ru{~6 onai-la bron ! MeERJcean ulcener: Ilutauft Abiat cizziile &a ped Tee Nokol 14rz priocpel LOmpencat Ennton CUEE  7anna Foniuina> 41d do Dmi Lobicco IMot Extciro anine NNK b' puwrerful pulmncnzny TC crcinogen, inducicg Net L17c PULaNn) prcdomanintly I15e adenocirarori thc lunz' onnneec miac 54 A4rau(ISn hinittc? refrru Jady e J Frtner Ibe roule oladminis Lit 14HigLo I7 [Nuom Tbc krot Eh GLA dun rconieca Anduce sxi4{66a1 urc; Ltakex Ukztteud AiLed Iag TAtAM WFA Tinalo duser yhict Imclas akculatcu Ucm Iilduet3 4maktijt1g'1O boi u Meoice, LitniAnLen amouh In Kcn Di munuclm Bctc prure %ukui61 ezarcite Mlo-rkidluc $4 Jmcic m W I Ttuuicuienig HdIuzbol mrllelite nafon_I 470ot Qute CdkO ~bk Ideacun Liate Watir Ranbu_ Orq retginctesgs_uee4h Tou454 3i 4u7-aonge {CJ7i" Aytnteteln met OH onenti:fig, LaFptd 01 92- n04l Nra Cuc ~1ndlf4 55a nici6# Uru6789u1n6U 56fA70 Cel Fnid Kanl, RRIEte 1