PRINCIPAL INVESTIGATORIFROGRAM DIRECTOR: BIOGRAPHICAL SKETCH listed Begin wilh Ihe Principal Give the following informalicn Icr Ine key Pcrsonne Page consumtanis Pholocopy Ihis page Investigator Program Direciar. lor eich peison NDouglas C Hixson POSITIONTITLE BIRTHDATE (Mo: Day, Yr} Oncologist Assoc. Research 6/21/47 other inilia' Prolessional pstdoctoral tralning } EDUCATION (Begin with baccalaureate Aucation Such anmincluoe nuisind EAR INSTITUTION AND LCCATION DEGREE FIELD OF STUDY CONFERRED ~Purdue University, W: LaFayette, IN BS 1969 Mathemabcs W. LaFayette, IN Purdue University MS 1971 Bio/Biochemis The Univ. of Texas Graduate School of Biomedical Sciences, Houston; TX 1975 Ph.D Biomed. Sciences RESEARCH AND FROFESSIONAL EXPERIENCE: Concluding wilh presenl Fosition; list, chronologicil order, prevlous Omployment, oxpedence order; Ihe lilles and ccm: Gcverninent public ecvisory commillee LisL chronologica andhcnors Iinciuce present memdershioonany Federa publizalions during the past thrco representallve earlier publlcalions pertinent Ihis application: DO NOT pleie relerenca: YLats EXCEED TWO PAGES. 1972-1975 Rosalie B; Hite Predoctoral Fellow in Virology, The Univ. of Texas MD. Anderson Hospital and T Houston, Texas Virology. 1975-1976 The Univ. of Texas MD Anderson Hospital and Tumor In: Project Investigator; Dept: of Houston, Texas Biochemistry and Virology, 1976-1977 The Univ. of Texas MD. Anderson Hos] Research Associate, Depts_ Tumor Institute, Houston; Texas 1977-1985 Associate Biochemist and Assistant Professor of Biochemistry, Thc Univ. of Texas System Cancer Science Park-Research Division Smithville, Texas Associate Research Oncologist, Rhode Island 1985- Hospital, Providence, Rhode Island; Pathology, Brown University, Providence, RI Associate Professor of Medicine and Publications: Walborg; Neri; G M Giuliano, S. Capetillo, E D Hixson and EF aggluti Gilliam "Lectin-induced glycopeptides and effect of neuraminidase - Novikoff hepatoma cells: Lectin receptor activity of cell-surface Res , 35.263-268, 1976. cytoagglutination Canccr Walborg Neri, G_ M Giuliano D Hixson and EF "The role of surface sialic acid in lectin-indu cell agglutination %f Novikoff hepatoma cells In: Membranes and Discases; (L. Bolis, J Hoffman and A. Le Raven Press, New York; NY' 1976, PP: 163-172. Neri, G,, MC Giuliano; S.C  Capetilio, E.G. Gilliams, D.C Hixson, a"Regulago? Walborg " and EF Jr,, surface sialic acid in lectin-induced cytoagglutination of rat hepatoma cells: Acta Medicz Romana Starling, Walborg: . JJDC Hixson and EF Surface properties of adult rat hepatocyte: EM Davis Exp Cell Res , 104:165, of increased concanavalin A-induced agglutinability following papain digestion: Chan, J.C. D.C. Hixson and J. M "Detection of vesicular stomatitis virus (Murine leukemia vin Bowen Pseudotypes of immunoelectron microscopy Virology 88.171, 1978. Hixson, DC, JM Scanlon, M. Nash and Strain related variations in the ini Dmochowski. Bowen 'Blat! ferritin conjugated lectins with murine mammary tumor viruses Cancer Res_ 39:199, 1979. abolc onhtbitors; Glenney, IR; Hixson and EF "Inhibition of concanavallin A-induced agglutinatio: Jr,, hepatoma cells by cytochalasins and metabolic Role of cell-surface morphology and topography Res-, 118.353-364, 1979 Walborg; Jr. Hayes; J.M Yep, JR. Glenney, Jr_, T: Hixson and EF "Evaluation of DC: ~linking plasma membrane glycoprotcins: periodate /ysine/paraformaldehyde fixation as method for crOSS Histochen_Cvtochem , 29.561-566, 1981. P4S 393 {Rev. 9188) Paca Tumhe Do "lea Hunlliat panes consecune , colicin IoucnouiMie ap0 Icution
PRINCIPAL INVESTIGATORIFROGRAM DIRECTOR: BIOGRAPHICAL SKETCH Give the following informalicn Icr Ine key Pcrsonne consumtanis listed Page Begin wilh Ihe Principal Investigator Program Direciar. Pholocopy Ihis page lor eich peison NDouglas C Hixson POSITIONTITLE Assoc. Research Oncologist BIRTHDATE (Mo: Day, Yr} 6/21/47 EDUCATION (Begin with baccalaureate other inilia' Prolessional Aucation Such nuisind anmincluoe pstdoctoral tralning } EAR DEGREE FIELD OF STUDY CONFERRED BS 1969 Mathemabcs MS 1971 Bio/Biochemis INSTITUTION AND LCCATION ~Purdue University, W: LaFayette, IN Purdue University W. LaFayette, IN The Univ. of Texas Graduate School of Biomedical Sciences, Houston; TX 1975 Ph.D Biomed. Sciences RESEARCH AND FROFESSIONAL EXPERIENCE: Concluding wilh presenl Fosition; list, chronologicil order, prevlous Omployment, oxpedence andhcnors Iinciuce present memdershioonany Federa Gcverninent public ecvisory commillee LisL chronologica order; Ihe lilles and ccm: pleie relerenca: publizalions during the past thrco YLats representallve earlier publlcalions pertinent Ihis application: DO NOT EXCEED TWO PAGES. 1972-1975 Rosalie B; Hite Predoctoral Fellow in Virology, The Univ. of Texas MD. Anderson Hospital and T Houston, Texas 1975-1976 Project Investigator; Dept: of Virology. The Univ. of Texas MD Anderson Hospital and Tumor In: Houston, Texas 1976-1977 Research Associate, Depts_ Biochemistry and Virology, The Univ. of Texas MD. Anderson Hos] Tumor Institute, Houston; Texas 1977-1985 Associate Biochemist and Assistant Professor of Biochemistry, Thc Univ. of Texas System Cancer Science Park-Research Division Smithville, Texas 1985- Associate Research Oncologist, Rhode Island Hospital, Providence, Rhode Island; Associate Professor of Medicine and Pathology, Brown University, Providence, RI Publications: Neri; G M Giuliano, S. Capetillo, E Gilliam D Hixson and EF Walborg; "Lectin-induced aggluti Novikoff hepatoma cells: Lectin receptor activity of cell-surface glycopeptides and effect of neuraminidase - cytoagglutination Canccr Res , 35.263-268, 1976. Neri, G_ M Giuliano D Hixson and EF Walborg "The role of cell surface sialic acid in lectin-indu agglutination %f Novikoff hepatoma cells In: Membranes and Discases; (L. Bolis, J Hoffman and A. Le Raven Press, New York; NY' 1976, PP: 163-172. Neri, G,, MC Giuliano; S.C  Capetilio, E.G. Gilliams, D.C Hixson, and EF Walborg " Jr,, a"Regulago? surface sialic acid in lectin-induced cytoagglutination of rat hepatoma cells: Acta Medicz Romana Starling, JJDC Hixson EM Davis and EF Walborg: . Surface properties of adult rat hepatocyte: of increased concanavalin A-induced agglutinability following papain digestion: Exp Cell Res , 104:165, Chan, J.C. D.C. Hixson and J. M Bowen "Detection of vesicular stomatitis virus (Murine leukemia vin Pseudotypes of immunoelectron microscopy Virology 88.171, 1978. Hixson, DC, JM Bowen Scanlon, M. Nash and Dmochowski. Strain related variations in the ini ferritin conjugated lectins with murine mammary tumor viruses Cancer Res_ 39:199, 1979. Glenney, IR; Jr,, 'Blat! Hixson and EF abolc onhtbitors; "Inhibition of concanavallin A-induced agglutinatio: hepatoma cells by cytochalasins and metabolic Role of cell-surface morphology and topography Res-, 118.353-364, 1979 Hixson DC: J.M Yep, JR. Glenney, Jr_, T: Hayes; and EF Walborg; Jr. "Evaluation of periodate /ysine/paraformaldehyde fixation as method for crOSS ~linking plasma membrane glycoprotcins: Histochen_Cvtochem , 29.561-566, 1981. P4S 393 {Rev. 9188) Tumhe panes consecune , Paca colicin IoucnouiMie ap0 Icution Do "lea Hunlliat