Investgato Program Director (Lasi_{rst_middlel: p[incioal BIOGRAPHICAL SKETCH Give the fcllcwing inlommation for the key perscnnol and consuilants and collaboralors Begin wilh Ihe principa Investigatortprogram Girector . Pnoroccpy this page Ior each porscn NAME POSITION TITLE Ginette Serrero Senior Scientist (Begm EDUCATICN other initial Molcsscal education Drccaauicali such aiuSug_an ncd:midotlon Vanino ) YEAR INSTITUTION AND LOCATICN DEGREE CONFEARED Of STUDY FIELD University of Nice, Nice, FRANCE B.S Biology & Biochemistry 1973 University of Marseille, Marseille, FRANCE Biochemistry Ph,D 1975 Universily of Nice. Nice, FRANCE Biology Doct: es Sci 1982 RESEAACH AND PROFESSIONAL EXPERIENCE: Concluding wiln present position, list, In chrorological order, Previcus emoloymenl pxpenance Koy porsonnel inctude the Princlpal (nvostigator and Inalvlduals #tho participate andhonon sciantitic deve coment Bxecubon typicaly will inclrde irdivduals %itn doclcral proiec: dateonne other profeasional degrees but in sc70 projects will include Indiv duals provded they contnbute masters Jachlaureate the scierilic develosmont Substantiva Wvay the prciec: Include presont execuan Federal Govcrmont publlc advisory commlitee unumnburstin Ust chronological ordor; Ine btles, authors; corplete reforences publications pubucalicns dunng Ihe past Inree years and mncrnsontitvo cadie thls appllcation: CO NOT EXCEED TWO PAGES Darinent Research Assistant, University 1973 1975 Nice , France Visiting Scientist, Dept of _ University of Calif. Biology Dicgo . 1976 1978 San La Jolla 1978 1989 Investigator 0n Icave trom Cente National de Ia Recherche Scientifique France Centre de Biochimie , University of Nice. France Post-doctoral Rescarch Biologist III, Cancer Center, University of California , San 1982 1983 Dicge, La Jolla, CA Old Bar Road , Lake Placid, NY 1983 1984 Visiticg Scicntist; W. Alton ones Cell Science Center, 1984 Scnior Scicntist; W. Alton Jones Cell Science Center, Old Barz Road, Lake Placid picscnt NY Dpt of Biology Burlington, VT present 1986 Adjuuct Assistant Professar, University 0f eront, Adjunct Assistant Professor, Dept. of Biology 1987 present Clarkson University Potsdam , NY HONORS: Delegation Generale de la Rccherche Scientifique et Technique France 1976 1978 Fellowship from the NATO Exchange Program Fellowship 1979 1980 1984 [986 Diahetes Research Award from New York State Health Department PUBLICATIONS: (since 1984) to study adipose differentiation Serrero J.C. Khoo 1982 and W YQ model serum-free medium, Biochem . 420:351-359 Anal_ Gaillard , Negrel, G Ailhaud   (1984) Growth of pre-adipocyte cell Serrero and G_ Lines and cell Vitro Cell. 20:79- strains from rodents in serum-frce hormone-supplemented medium_ Devel: Biol. Study of Serrero (1984) teratoma-derived_ adipogenic cell line 1246 and  isolation of an insulin "Biologz independent variant in serum-free medium_ Hormonally Defined Media Tool in Cell (G Heidelberg; New York, Tokyo . Pp. eds.) , Springer-Verlag Fisher and R_ Wieser Berlin Serrero (1984) line Growth and differentiation of pre-adipocyte cell in  serum-free medium -Free Hormone-Supplemented Media Mammalian Celi Culture_ The Use of Serum (I.P. Mather , ed.), Pp. 53-76 Plenum Press, NY Serrero 985) Tumorigenicity associated the loss of differentiation and of response to insulin in with the adipogenic cell line 1246. In Vitro Ccll; Biol._2:537-540 Dcvel: Yamada_ and G Serrero 1986) Characterization of an insulin-related factor secreted by teratoma cell 135.533-540. Biochem . Biophys_ Res Commun line Serrero Endocrine and autocrine control of growth and differentiation of teratoma-derived cell 1986) Cellular Endocrinology Vines Hormonal Control of Embryonic and Cellular Differentiation, (G Hayashi, eds Serrero and Alan R Liss Inc NY 191-204_ dRerentiation Serrero_ using and Mills 986) Assay for adipose primary culture of adipocyte Tissue Culture Methods . 10;75 precursors_ 1987) Yamada and G_ Scrrcro Purification of an insulin-related factor (IRF) secreted by teraloma 262:209-213_ derived mesodermal cell line_ Biol, Chem Serrero and D Mills (1987) Differentiation of newborn rat adipocyte precursors in defined serum-frce medi 2363-66 InKito CelL_Devel Biol PHS 398 (Rov. 9/91} (Fom Page Number pages consecubvaly 8t ta boltcm tholghout Ihe apctcaton not UsO suitues Slch As %a. 3 40001212
p[incioal Investgato Program Director (Lasi_{rst_middlel: BIOGRAPHICAL SKETCH Give the fcllcwing inlommation for the key perscnnol and consuilants and collaboralors Begin wilh Ihe principa Investigatortprogram Girector . Pnoroccpy this page Ior each porscn  NAME POSITION TITLE Ginette Serrero Senior Scientist EDUCATICN (Begm Drccaauicali other initial Molcsscal education such aiuSug_an ncd:midotlon Vanino ) YEAR INSTITUTION AND LOCATICN DEGREE CONFEARED FIELD Of STUDY University of Nice, Nice, FRANCE B.S 1973 Biology & Biochemistry University of Marseille, Marseille, FRANCE Ph,D 1975 Biochemistry Universily of Nice. Nice, FRANCE Doct: es Sci 1982 Biology RESEAACH AND PROFESSIONAL EXPERIENCE: Concluding wiln present position, list, In chrorological order, Previcus emoloymenl pxpenance andhonon Koy porsonnel inctude the Princlpal (nvostigator and Inalvlduals #tho participate sciantitic deve coment Bxecubon proiec: dateonne typicaly will inclrde irdivduals %itn doclcral other profeasional degrees but in sc70 projects will include Indiv duals masters Jachlaureate provded they contnbute Substantiva Wvay the scierilic develosmont execuan the prciec: Include presont unumnburstin Federal Govcrmont publlc advisory commlitee Ust chronological ordor; Ine btles, authors; corplete reforences pubucalicns dunng Ihe past Inree years and mncrnsontitvo cadie publications Darinent thls appllcation: CO NOT EXCEED TWO PAGES 1973 1975 Research Assistant, University Nice , France 1976  1978 Visiting Scientist, Dept of _ Biology University of Calif. San  Dicgo . La Jolla 1978 1989 Investigator 0n Icave trom Cente National de Ia Recherche Scientifique France Centre de Biochimie , University of Nice. France 1982 1983 Post-doctoral Rescarch Biologist III, Cancer Center, University of California , San Dicge, La Jolla, CA 1983 1984 Visiticg Scicntist; W. Alton ones Cell Science Center, Old Bar Road , Lake Placid, NY 1984 picscnt Scnior Scicntist; W. Alton Jones Cell Science Center, Old Barz Road, Lake Placid NY 1986 present Adjuuct Assistant Professar, Dpt of Biology University 0f eront, Burlington, VT 1987 present Adjunct Assistant Professor, Dept. of Biology Clarkson University Potsdam , NY HONORS: 1976 1978 1979 1980 1984 [986 Fellowship from the Delegation Generale de la Rccherche Scientifique et Technique France NATO Exchange Program Fellowship Diahetes Research Award from New York State Health Department PUBLICATIONS: (since 1984) Serrero and J.C. Khoo 1982 W YQ model to study adipose differentiation serum-free medium, Anal_ Biochem . 420:351-359 Gaillard , Negrel, G Serrero and G_ Ailhaud   (1984) Growth of pre-adipocyte cell Lines and cell strains from rodents in serum-frce hormone-supplemented medium_ Vitro Cell. Devel: Biol. 20:79- Serrero (1984) Study of teratoma-derived_ adipogenic cell line 1246 and  isolation of an insulin independent variant in serum-free medium_ Hormonally Defined Media Tool in Cell (G Fisher and R_ Wieser eds.) , Springer-Verlag Berlin Heidelberg; "Biologz New York, Tokyo . Pp. Serrero (1984) Growth and differentiation of pre-adipocyte cell line in  serum-free medium Mammalian Celi Culture_ The Use of Serum -Free Hormone-Supplemented Media (I.P. Mather , ed.), Plenum Press, NY Pp. 53-76 Serrero 985) Tumorigenicity associated with the loss of differentiation and of response to insulin in the adipogenic cell line 1246. In Vitro Ccll; Dcvel: Biol._2:537-540 Yamada_ and G Serrero 1986) Characterization of an insulin-related factor secreted by teratoma cell line Biochem . Biophys_ Res Commun 135.533-540. Serrero 1986) Endocrine and autocrine control of growth and differentiation of teratoma-derived cell Vines Cellular Endocrinology Hormonal Control of Embryonic and Cellular Differentiation, (G Serrero and Hayashi, eds Alan R Liss Inc NY 191-204_ Serrero_ and Mills 986) Assay for adipose dRerentiation using primary culture of adipocyte precursors_ Tissue Culture Methods . 10;75 Yamada and G_ Scrrcro 1987) Purification of an insulin-related factor (IRF) secreted by teraloma derived mesodermal cell line_ Biol, Chem 262:209-213_ Serrero and D Mills (1987) Differentiation of newborn rat adipocyte precursors in defined serum-frce medi InKito CelL_Devel Biol 2363-66 PHS 398 (Rov. 9/91} (Fom Page Number pages consecubvaly 8t ta boltcm tholghout Ihe apctcaton not UsO suitues Slch As %a. 3 40001212