Baekkeskov Steinunn Parcpal Invasbzator Pronrm Director (Last 6in5t middek BIOGRAPHICAL SKETCH Gi Icloxing Inbmmabon Ior tha key personnel and consutlants and ccllaboratcts Begin wm the pnncipal investgator program diractox; FhcbEi this paga fy nach perscn NAME POSITION TMLE BAKKESKOV, Steinunn Asscciate Professor EOHNEEFHIEExue1CEHE7Ladeszbnaleureaton zcha3n4NMhe1LIDLOPOSEEEKZ EAA INSTITUTION AND LOCATION CONFERRED DEGREE FIELD OF STUDY University of Copenhagen, Copenhagen, DK Cand Scient Biochemistry MS /PhD 1976 Diseases Int: Lab. Res Nairobi, Kenya Biochemistry Animal Postdoc; 1977-79 Hagedorn Research Laboratory, Copenhagen, DK Postdoc 1980-82 Immunology of Diabetes University of Copenhagen Copenhagen DK Immuology Ph D 1984 Lic Scient RESEARCH AND PROFESSIONAL EXPERIENCE: Ccacluping "th present positon; Iist chronological order; prerous omployment expenanca;and Key Personnel include the pinclpel Inveat gator and any cther ndlvlduals who paricipate in the scieniif c Development Fonct executon of tna prolect typ cally wI includ? cthor prolessional cegrees Eutin some projecrs will Include Individua $ at 070 Masters Kay nereonne nanolas dcctora level provided may conlributa in & substantvo way 1o tho scienunc devebprent execution otthe Indude Fresee CerCaatKa3ri ellwco Metoeisho 0n Lsl Government public advsory comitioo an Fecami Jen8 chconclogial crdor; ne lijos, O.e relerences publicarions during autnctg DO NOT EXCEED PAGES: Lne past nmea vbans and ID reDresentavyt gang puC icaia s peMrent l0 mhig aroicaton RESEARCH AND PROFESSIONAL EXPERIENCE Student Research Fellow, Dept: of Chemistry, Carlsberg Laboratory; Copenhagen, Denmark: 1973-1975 Thesis: Isolation, characterization, and chemical modification of glucose-6-phosphate dehydrogenase from Saccharomyces cerevisae. Biochemistry, University of Copenhagen, Faculty of Medicine, Copenhagen, Denmark 1976 Lecturer in 1977-1979 Postdoctoral Felow, Dept; of Biochemistry, International Laboratory lor Research on Animal Diseases (ILRAD), Nairobi, Kenya_ Hagedorn Research Laboratory, Copenhagen, Denmark. 1980-1982 Postdoctoral Fellow 1982-1986 Staif Scientist; Hagcdorn Research Laboratory Hagedorn Research Laboratory. 1986-1989 Senior Staff Scientist; Microbiology / Immunology, UCSF 1989-1992 Assistant Professor, Depts: of Medicine and Microbiology / Immunology, UCSF 1992 Associate Professor, Dept; of Medicine and HONORS AND AWARDS 1982-1984 Juvenile Diabetes Foundation Research Fellowship Juvenile Diabetes Foundation Career Development Award 1984-1987 1991-1993 NIH Shannon Award SELECTED PUBLICATIONS (Total: Included are selected publications prior to 1990 and all but book Edme from 1990 to present) chapters and Fevip@ and Baekkeskov, Rovis, Trypanosoma brucei. Subccllular fractionation of Isolation and characterization of Parasitology 80, 507-524 (1980). plasma membranes: Klareskog; Bekkeskov, $ Kana L, Nielsen; DA , Peterson; P.A: Itsuna, T. Rubenstein, A.H , Steiner, DF and Expression of major histocompatibility antigens pancreatic islet cells. Lemmark, Froc. Nall. Acad. Sci: USA 78, 6456-6460 (1981). Baekkeskov, 5 , Nielsen, JH , Mamer, Bilde Ludvigsson; and Lernmark; Autvantibodies in newly diagnosed diabetic children immunoprecipitate specilic human pancreatic islet cell proteins_ Nature 298, 167-169 982). and Lernmark; Dyrberg Baekkeskov Specific pancreatic b-cell surface antigens recognized by Biol- Cell xenogenic antiserum 94, 472-477 (1982}. Baekkeskov, $: and Lernmark; Glucase stimulates the biosynthesis of human pancreatic islet cell protein against the human erythrocyte glucose transporter. FEBS Letters 157, 331-335 (1983). detected by an antiserum Baekkeskov, $ , Dyrberg; T and Lernmark; against an Mr 64K islet cell protein precede the Autoantibodies of insulin-dependent diabetes in the BB-rat. Science 224, 1348-1350 (1984}. onsel Gerling; Baekkeskov, 5. and Lernmark, Islet cell and 64K autoantibodies are associated with plasma IgG in newly diagnosed insulin-dependent diabetic children, [mmunol. 137 , 3782-3785 (1986). PHS 398 (Rev. 991} (Fon Page 6) Page Numbar pagos consecutive } &: me bottom trcugrut the appFcaton Do notuse atfxes sch as 34, 30
Baekkeskov Steinunn Parcpal Invasbzator Pronrm Director (Last 6in5t middek BIOGRAPHICAL SKETCH Gi Icloxing Inbmmabon Ior tha key personnel and consutlants and ccllaboratcts Begin wm the pnncipal investgator program diractox; FhcbEi this paga fy nach perscn NAME POSITION TMLE BAKKESKOV, Steinunn Asscciate Professor EOHNEEFHIEExue1CEHE7Ladeszbnaleureaton zcha3n4NMhe1LIDLOPOSEEEKZ EAA INSTITUTION AND LOCATION DEGREE CONFERRED FIELD OF STUDY University of Copenhagen, Copenhagen, DK MS /PhD 1976 Cand Scient Biochemistry Int: Lab. Res Animal Diseases Nairobi, Kenya Postdoc; 1977-79 Biochemistry Hagedorn Research Laboratory, Copenhagen, DK Postdoc 1980-82 Immunology of Diabetes University of Copenhagen Copenhagen DK Ph D 1984 Lic Scient Immuology RESEARCH AND PROFESSIONAL EXPERIENCE: Ccacluping "th present positon; Iist chronological order; prerous omployment Fonct expenanca;and Key Personnel include the pinclpel Inveat gator and any cther ndlvlduals who paricipate in the scieniif c Development executon of tna prolect Kay nereonne typ cally wI includ? nanolas dcctora cthor prolessional cegrees Eutin some projecrs will Include Individua $ at 070 Masters CerCaatKa3ri level provided may conlributa in & substantvo way 1o tho scienunc devebprent execution otthe ellwco Indude Fresee Metoeisho 0n an Fecami Government public advsory comitioo Lsl chconclogial crdor; ne lijos, autnctg Jen8 O.e relerences publicarions during Lne past nmea vbans and ID reDresentavyt gang puC icaia s peMrent l0 mhig aroicaton DO NOT EXCEED PAGES: RESEARCH AND PROFESSIONAL EXPERIENCE 1973-1975 Student Research Fellow, Dept: of Chemistry, Carlsberg Laboratory; Copenhagen, Denmark: Thesis: Isolation, characterization, and chemical modification of glucose-6-phosphate dehydrogenase from Saccharomyces cerevisae. 1976 Lecturer in Biochemistry, University of Copenhagen, Faculty of Medicine, Copenhagen, Denmark 1977-1979 Postdoctoral Felow, Dept; of Biochemistry, International Laboratory lor Research on Animal Diseases (ILRAD), Nairobi, Kenya_ 1980-1982 Postdoctoral Fellow Hagedorn Research Laboratory, Copenhagen, Denmark. 1982-1986 Staif Scientist; Hagcdorn Research Laboratory 1986-1989 Senior Staff Scientist; Hagedorn Research Laboratory. 1989-1992 Assistant Professor, Depts: of Medicine and Microbiology / Immunology, UCSF 1992 Associate Professor, Dept; of Medicine and Microbiology / Immunology, UCSF HONORS AND AWARDS 1982-1984 Juvenile Diabetes Foundation Research Fellowship 1984-1987 Juvenile Diabetes Foundation Career Development Award 1991-1993 NIH Shannon Award SELECTED PUBLICATIONS (Total: Included are selected publications prior to 1990 and all but Edme book chapters and Fevip@ from 1990 to present) Rovis, and Baekkeskov, Subccllular fractionation of Trypanosoma brucei. Isolation and characterization of plasma membranes: Parasitology 80, 507-524 (1980). Bekkeskov, $ Kana Itsuna, T. Klareskog; L, Nielsen; DA , Peterson; P.A: Rubenstein, A.H , Steiner, DF and Lemmark, Expression of major histocompatibility antigens pancreatic islet cells. Froc. Nall. Acad. Sci: USA 78, 6456-6460 (1981). Baekkeskov, 5 , Nielsen, JH , Mamer, Bilde Ludvigsson; and Lernmark; Autvantibodies in newly diagnosed diabetic children immunoprecipitate specilic human pancreatic islet cell proteins_ Nature 298, 167-169 982). Dyrberg Baekkeskov and Lernmark; Specific pancreatic b-cell surface antigens recognized by xenogenic antiserum Cell Biol- 94, 472-477 (1982}. Baekkeskov, $: and Lernmark; Glucase stimulates the biosynthesis of human pancreatic islet cell protein detected by an antiserum against the human erythrocyte glucose transporter. FEBS Letters 157, 331-335 (1983). Baekkeskov, $ , Dyrberg; T and Lernmark; Autoantibodies against an Mr 64K islet cell protein precede the onsel of insulin-dependent diabetes in the BB-rat. Science 224, 1348-1350 (1984}. Gerling; Baekkeskov, 5. and Lernmark, Islet cell and 64K autoantibodies are associated with plasma IgG in newly diagnosed insulin-dependent diabetic children, [mmunol. 137 , 3782-3785 (1986). PHS 398 (Rev. 991} (Fon Page 6) Page Numbar pagos consecutive } &: me bottom trcugrut the appFcaton Do notuse atfxes sch as 34, 30