RJR INTER-OFFICE MEMORANDUM 986 June To: Dr" . Bob Suber From: Oebor&h Lee Cindy Fulp Inc (ron Haz eton Bfo echno 0pics Subj ect: Anes results HB / samp H8| (Firnova for samplc The follouing results obtained Werc Powder 850 035 ) : 59 ACTIVATION 1537 1538 Taido 535 strain strain strain Ta98 #roin strain (revLng gamplel s4ple) (evLoa Lrevlop sarp le LeyLm banple (reylog Ba0pE 0887 (neg) negative (neq 350 5.30 (neg) "8 (ned ) 59 ACTIUATION 107 strain 1538 strain 1535 1537 stroin Ta98 1ai0) strain tral (rexLng Janplel LrevLnn jpke frevlrq ganple (revLmg 2emple) (revLng napple 816 (neg 03 (nep) 05 (neg) (ned 692 (neg} 500 020 2509 5020 and The tested 100 Conc)u; {0nx i range dose Vas There significant i0u0u ug in 50 u] Increase Ud5 HB | in dose level sampi revertant nunber 1ncrcdse for the 5 etrains uith Wiltout ivation ac [ these results uith Tob _ Please feel free cur cuss und Cindy Fud Lee 6.1 . Burner J.R_ Hayes
RJR INTER-OFFICE MEMORANDUM 986 June To: Dr" . Bob Suber From: Oebor&h Lee Cindy Fulp HB / (ron Haz eton Bfo echno 0pics Inc Subj ect: Anes results samp The follouing results Werc obtained for samplc H8| (Firnova Powder 850 035 ) : 59 ACTIVATION strain Ta98 #roin Taido strain 535 strain 1537 strain 1538 Lrevlop sarp le LeyLm banple (reylog s4ple) (evLoa Ba0pE (revLng gamplel 0887 (neg) negative 350 (neq 5.30 (neg) "8 (ned ) 107 59 ACTIUATION stroin Ta98 tral 1ai0) strain 1535 strain 1537 strain 1538 (revLmg 2emple) (revLng napple (rexLng Janplel LrevLnn jpke frevlrq ganple 816 (neg 03 (nep) 05 (neg) (ned 692 (neg} Conc)u; {0nx i The dose range tested Vas 100 500 020 2509 5020 and i0u0u ug in 50 u] There Ud5 significant Increase revertant nunber 1ncrcdse in dose level sampi HB | uith Wiltout ac [ ivation for the 5 etrains cuss these results uith cur Tob _ und Cindy Fud Please feel free Lee 6.1 . Burner J.R_ Hayes