PRINCIFAL INVESTIGATOR/PROGRAH DiRECTDR: BIOGRA PHICAL SKETCH listed poge 2, beginning with the Give the following infomotion for key professional personne Principal Investigator /Program Director: Photocopy this page for each Person: BIRTHDATE (o ,poy,Ya) Title NAME 08/27/40 Assistant Professor Phillip Stone and include Dexloo ctorol EDUCA TION (Begin Jaccoloureote Telning EAR FIELD OF Study DEGREE institution AND LOCATION CONFERRED Swarthnore_College 1962 CheniaLly PennsxLyania Physical Chenistry 1965 Pena University_Qf Ph D 1971 Inorganic Chcniatry Tenele Vniversity arder Prayiour smplornanl ErPafie RESE-RCH ANd/or PROFESSIONAL EXPERIENCE: Coneluding Kiih presaen Joplsal pogimion, Chtonc cironologicel ordar, tha itler and memborship Govcmmant Poblic Advliony Conmikoo, Faderoi andihanan Inelude present 5nce, 4ed Publieations Il, cPelicaticn pae0 19772284 mroncloll Moit Partinan edeeentoly {elerenco> Tacor Boston Wnivergizy School of Research Asgociate, Departnent of Biochenistry, Medicine_ School of Medicine_S of Biochenistry Boston University Departnent 1974-76. Instructor Biochenistry_ Boston University School Assistant Departnent 1976 Profesgor_ Present. Hedicine. Research (NIE) Young Investigator Pulnonary 1974-76 Fonor6: Publicationg' and Dori, Z. Sone Nickel (II) Complexes Containing the Liganda Cyclo- Stone, P.J e phenylphosphine, Dicyclohexylphenylphosphine and Tricyclohexylphosphine. hexyld 434-438 (1971). Inorganica Chimica Acta The Interaction of Cis-Pt(NH3) 2C12 with DNA. Published Sinex, F.M Stone P_ and Coordination Conplezee i2 Cancer Chenotherapx, I.. Connors and J in Platinue 1974, PP.67-69 Springer-Verlag, Berlin, (eds.), Roberts and Sinex, FM. Specific Binding of Antitunor Drug Cig-Pt (NE3' 2C12 to Stone RJJ: Nature 25L, 736-737 , (1974)_ DNA Rich in Guanine and Cytosine Franzblau, C., Kagan, H.M:, Stone: P-J  and Korthy, AL. Hayes , Snider, G.L. JA:, and Experinental Enphysema-Inducing Proper- Relationship betveen Elastolytic Activity Dis. 4O, 254-262 (1974) . of Papain Preparatione Aner Rev Rebp: ties Hoppin, F.G J.B., Snider, G.l , Franzblau, C , Stone, R Ja Kerlinksy and Lungs. on   Mechanical Properties Vitro Effects of Hanster Elastage and Collagenage 4L, 769-777 (1976)_ Reep- Rev _ Dis. Aner and Kalvorson, Kelqan, AD , Sinex, RH:, Bhargava, KX, L.0. Resolu- PJJ Stone 36 DNA of Seccharonyceg cervisiae vith the Antitunor Drug Cig-Pt and& tion Sequences of DNA: J. Mol 81o1.32, Evidence for Preferential Drug Binding by GPG 793-801 (1976)_ Binding of Peresie, RJJ and Gtone, R.J An Analysis of the Hodes A.Da, Keluan, 640-453   (1977). Complexe: DNA _ Clin. Henatol. Oncol. Antitumor Platinum and Franzblau, The G.L-, Kagan, E.H:; Bilee Snider, PJJe Pereira Stone Of Intratracheal "14C-Guanidinated Rancreatic Eiastase in Hanscef Lung, Fate %ed.} oienua Eressi-u evd {0.ksti94{i913 Kedicine L.B in Experinental Advancee 1977 .  P.233-248_ York Sandberg, Franzblau Plenum Press, Nex R_ Gray and The Kinetics of Elastolysis a8 and Franzblau, C D., Kagap , E.M: Scone Faris R.Ja P597-600 . Elastic. Ibid Probe end Franzblau, Lerch, RH , Mukherjee, DP , Stone: R.J , Jordan, RE:, Kagan H:X. Ibid, P.189-207_ the Proteolytic Degradation of Elastin Factors Affecting PH5 J98 PaGE_ SNIDER 19/79 50237584
PRINCIFAL INVESTIGATOR/PROGRAH DiRECTDR: BIOGRA PHICAL SKETCH Give the following infomotion for key professional personne listed poge 2, beginning with the Principal Investigator /Program Director: Photocopy this page for each Person: Title BIRTHDATE (o ,poy,Ya) NAME 08/27/40 Assistant Professor Phillip Stone Jaccoloureote Telning and include Dexloo ctorol EDUCA TION (Begin institution AND LOCATION EAR FIELD OF Study DEGREE CONFERRED Swarthnore_College PennsxLyania University_Qf Pena  Tenele Vniversity 1962 1965 1971 CheniaLly Physical Chenistry Inorganic Chcniatry Ph D RESE-RCH ANd/or PROFESSIONAL EXPERIENCE: Coneluding Kiih presaen pogimion, Chtonc Joplsal arder Prayiour smplornanl ErPafie memborship Faderoi Govcmmant Poblic Advliony Conmikoo, cironologicel ordar, tha itler and 5nce, andihanan Inelude present edeeentoly Publieations mroncloll Moit Partinan Il, cPelicaticn 4ed Tacor pae0 19772284 {elerenco> Research Asgociate, Departnent of Biochenistry, Boston Wnivergizy School of Medicine_ 1974-76. Instructor Departnent of Biochenistry Boston University School of Medicine_S 1976 Assistant Profesgor_ Departnent Biochenistry_ Boston University School Present. Hedicine. 1974-76 Young Investigator Pulnonary Research (NIE) Fonor6: Publicationg' Stone, P.J e and Dori, Z. Sone Nickel (II) Complexes Containing the Liganda Cyclo- hexyld phenylphosphine, Dicyclohexylphenylphosphine and Tricyclohexylphosphine. Inorganica Chimica Acta 434-438 (1971). Stone P_ and Sinex, F.M The Interaction of Cis-Pt(NH3) 2C12 with DNA. Published in Platinue Coordination Conplezee i2 Cancer Chenotherapx, I.. Connors and J  Roberts (eds.), Springer-Verlag, Berlin, 1974, PP.67-69 Stone RJJ: and Sinex, FM. Specific Binding of Antitunor Drug Cig-Pt (NE3' 2C12 to DNA Rich in Guanine and Cytosine Nature 25L, 736-737 , (1974)_ Snider, G.L. Hayes , JA:, Franzblau, C., Kagan, H.M:, Stone: P-J  and Korthy, AL. Relationship betveen Elastolytic Activity and Experinental Enphysema-Inducing Proper- ties of Papain Preparatione Aner Rev Rebp: Dis. 4O, 254-262 (1974) . Kerlinksy J.B., Snider, G.l , Franzblau, C , Stone, R Ja and Hoppin, F.G  Vitro Effects Elastage and Collagenage on   Mechanical Properties of Hanster Lungs. Aner Rev _ Reep- Dis. 4L, 769-777 (1976)_ Stone PJJ Kelqan, AD , Sinex, RH:, Bhargava, KX, and Kalvorson, L.0. Resolu- tion 36 and& DNA of Seccharonyceg cervisiae vith the Antitunor Drug Cig-Pt Evidence for Preferential Drug Binding by GPG Sequences of DNA: J. Mol 81o1.32, 793-801 (1976)_ Keluan, A.Da, Peresie, RJJ and Gtone, R.J  An Analysis of the Hodes Binding of Antitumor Platinum Complexe: DNA _ Clin. Henatol. Oncol. 640-453   (1977). Stone PJJe Pereira Bilee Snider, G.L-, Kagan, E.H:; and Franzblau, The Fate Of Intratracheal "14C-Guanidinated Rancreatic Eiastase in Hanscef Lung, Advancee in Experinental Kedicine L.B  %ed.} oienua Eressi-u evd {0.ksti94{i913 Sandberg, R_ Gray and Franzblau Plenum Press, Nex York 1977 .  P.233-248_ Scone R.Ja Kagap , E.M: Faris D., and Franzblau, C The Kinetics of Elastolysis a8 Probe Elastic. Ibid P597-600 . Kagan H:X. Jordan, RE:, Lerch, RH , Mukherjee, DP , Stone: R.J , end Franzblau, Factors Affecting the Proteolytic Degradation of Elastin Ibid, P.189-207_ PH5 J98 19/79 PaGE_ SNIDER 50237584