Where is superoxide dismutase found in the body?
Three forms of superoxide dismutase are present in humans, in all other mammals, and most chordates. SOD1 is located in the cytoplasm, SOD2 in the mitochondria, and SOD3 is extracellular. The first is a dimer (consists of two units), whereas the others are tetramers (four subunits). SOD1 and SOD3 contain copper and zinc, whereas SOD2, the mitochondrial enzyme, has manganese in its reactive centre. The genes are located on chromosomes 21, 6, and 4, respectively (21q22.1, 6q25.3 and 4p15.3-p15.1).
Where is superoxide dismutase SOd1 found in the body?
cytoplasm
Superoxide dismutase
In higher plants, SOD isozymes have been localized in different cell compartments. Mn-SOD is present in mitochondria and peroxisomes. Fe-SOD has been found mainly in chloroplasts but has also been detected in peroxisomes, and CuZn-SOD has been localized in cytosol, chloroplasts, peroxisomes, and apoplast.
Where is superoxide dismutase SOd2 found in the body?
mitochondria
Superoxide dismutase
In mice, the extracellular superoxide dismutase (SOD3, ecSOD) contributes to the development of hypertension. Diminished SOD3 activity has been linked to lung diseases such as Acute Respiratory Distress Syndrome (ARDS) or Chronic obstructive pulmonary disease (COPD).
Where is superoxide dismutase SOd3 found in the body?
extracellular
Superoxide dismutase
Superoxide dismutase
https://en.wikipedia.org/wiki/Superoxide%20dismutase
In cell biology, the cytoplasm is all of the material within a eukaryotic cell, enclosed by the cell membrane, except for the cell nucleus.
Cytoplasm
A mitochondrion (/ˌmaɪtəˈkɒndriən/,[1] plural mitochondria) is a double membrane-bound organelle found in most eukaryotic organisms.
Mitochondrion
extracellular
Of or occurring in the space outside the plasma membrane of a cell.
Glossary of biology extracellular
Superoxide dismutase [Cu-Zn] also known as superoxide dismutase 1 or SOD1 is an enzyme that in humans is encoded by the SOD1 gene, located on chromosome 21.
SOD1
Three forms of superoxide dismutase are present in humans, in all other mammals, and in most chordates, SOD1, SOD2, and SOD3, each located in a different part of the body. Superoxide dismutase 1, or SOD1, is located in the cytoplasm, the material within a eukaryotic cell enclosed by the cell membrane except for the cell nucleus. SOD2 is found in the mitochondria, an organelle found in most eukaryotic organisms. Finally, SOD3 is extracellular, meaning it occurs in the space outside the plasma membrane of a cell.