Thibodaux (/ˈtɪbədoʊ/ TIB-ə-doh) is a city in and the parish seat of Lafourche Parish, Louisiana, United States, along the banks of Bayou Lafourche in the northwestern part of the parish. The population was 14,567 at the 2010 census.hey were challenged by a coalition of Populists and Republicans, as well as labor unrest as agricultural workers tried to organize to ease their conditions. A sugar cane workers' strike culminated in the  Thibodaux massacre  of November 22, 1887, one of the bloodiest labor disputes in U.S. history.