Insomnia hormones include estrogen and testosterone. Estrogen is a sleep-maintaining hormone. It is common to have an estrogen deficiency in perimenopause and menopause and when your body is not producing enough natural estrogen, your ability to get a full night's sleep suffers as a result.A lack of testosterone is also an issue for women.strogen is a sleep-maintaining hormone. It is common to have an estrogen deficiency in perimenopause and menopause and when your body is not producing enough natural estrogen, your ability to get a full night's sleep suffers as a result.