anomie. 1. (noun) Social instability caused by erosion or absence of morals, norms, standards and values in an individual or society. 2. (noun) A personal state of alienation, anxiety, and purposelessness caused by social instability and the loss of regulation.Audio Pronunciation: (an·o·mie).nomie. 1. (noun) Social instability caused by erosion or absence of morals, norms, standards and values in an individual or society. 2. (noun) A personal state of alienation, anxiety, and purposelessness caused by social instability and the loss of regulation.