6. All tubing will be changed every 72 hours except: a. Lipid tubing will be changed every 24 hours b. If lipids are IVPB into TPN, also change TPN tubing every 24 hours c. Change 3 in 1 TPN (TPN with lipids mixed in) every 24 hours 7. Leur loc connection must be used. Primary solutions must be administered via a volume control pump (i.e. Hospira pump). 8.