The Colosseum or Coliseum (/kɒləˈsiːəm/ kol-ə-SEE-əm), also known as the Flavian Amphitheatre (Latin: Amphitheatrum Flavium; Italian: Anfiteatro Flavio [amfiteˈaːtro ˈflaːvjo] or Colosseo [kolosˈsɛːo]), is an oval amphitheatre in the centre of the city of Rome, Italy.he Colosseum is generally regarded by Christians as a site of the martyrdom of large numbers of believers during the persecution of Christians in the Roman Empire, as evidenced by Church history and tradition.