To accomplish the tasks associated with digestion, the lysosomes use some 40 different types of lysosomal enzymes, such as glycosidases, protease, acid phosphatases, sulfatases and lipases.Lysosomal enzymes are synthesized in the endoplasmic reticulum and modified in the Golgi apparatus.ysosomal Enzymes. To accomplish the tasks associated with digestion, the lysosomes use some 40 different types of lysosomal enzymes, such as glycosidases, protease, acid phosphatases, sulfatases and lipases. Lysosomal enzymes are synthesized in the endoplasmic reticulum and modified in the Golgi apparatus.