Buspirone Dosage. Buspirone comes in tablets of 5, 10, 15, or 30 milligrams (mg). The tablets have a scored mark down the middle so you can split a pill in half if necessary. A typical dose starts at 7.5 mg every 12 hours. Your doctor may increase your daily dose by 5 mg every few days if needed.An average daily dose is 20 to 30 mg a day in divided doses. The maximum daily dose is 60 mg. Always take buspirone at the same time each day, with or without food.n average daily dose is 20 to 30 mg a day in divided doses. The maximum daily dose is 60 mg. Always take buspirone at the same time each day, with or without food.