Things You'll Need. Turn the oven on to 350 degrees and line a baking sheet with parchment paper or lightly grease with olive oil. Cut the tortillas into eighths. Use whole wheat or chili and lime tortillas to make flavored tortilla chips. Arrange the tortilla wedges in a single layer on the baking sheet. Drizzle olive oil over the tortilla wedges and sprinkle with salt and dried spices, such as cumin or paprika, if desired.