Playing 'Big Brother' Host Julie Chen Emotional Over Transgender Houseguest. ET chatted with Big Brother host Julie Chen about the reality show including its first transgender houseguest, which she says had nothing to do with Caitlyn Jenner's story. Audrey Middleton is a 25-year-old digital media consultant from Villa Rica, Georgia. NEWS: Big Brother Will Have Its First Transgender Houseguest. Audrey's application was in last year before any of the Caitlyn Jenner story happened, Chen told ET.