Raspberry ketones in food and cosmetics are generally considered safe. But no one knows what short-or long-term effect raspberry ketone supplements could have on your overall health. No study has been done to document potential side effects.There are also no studies that look at potential drug or food interactions.he fact that raspberry ketones chemically resemble other stimulants suggests the potential for certain side effects. And there are anecdotal reports of jitteriness, increased blood pressure, and rapid heartbeat among people taking raspberry ketone supplements.