Progestogen is a steroid hormone that acts like progesterone, a hormone that prepares the uterus for pregnancy. Progestogen is used in oral contraceptives and to treat gynecological disorders. Contraceptive pills may contain estrogen and progestogen, or only the latter. Progesterone is a naturally produced progestogen that prepares the uterus to accept a fertilized egg. Progestogen is a steroid hormone that acts like progesterone, a hormone that prepares the uterus for pregnancy.