Female squirrels have one litter per year and usually have 9 babies. That is all I know on that one. Female squirrels can have 2 litters per year with 1-4 babies per litter. Female squirrels have one litter per year and usually have 9 babies. That is all I know on that one. <br /> JKams<br />Female squirrels can have 2 litters per year with 1-4 babies per litter.