L. acidophilus may help in the treatment of chronic constipation by helping restore balance and regularity to the digestive system. According to the National Institutes of Health, L. acidophilus is often used to treat irritable bowel syndrome, or IBS, which may cause alternating bouts of diarrhea and constipation.actobacillus acidophilus, a well-known probiotic, is a type of healthy bacteria that offers numerous health benefits.