HPV vaccine. Gardasil-9 is one of three FDA-approved HPV vaccines. It is recommended for both males and females. It is routinely given at 11 or 12 years of age, but it may be given beginning at age 9 years through age 26 years for females and males. Three doses of Gardasil-9 are recommended with the second and third dose 2 months and 6 months after the first dose.