Acute graft versus host disease generally happens within the first 100 days after bone marrow or stem cell transplant. Sometimes it can be hard to tell if the symptoms are caused by GVHD, or are other side effects of your transplant. The symptoms of GVHD depend on which part of the body is affected. There is information below about. 1  Acute skin GVHD. 2  Acute liver GVHD. 3  Acute gut (digestive system) GVHD. 4  Other symptoms.