Receptor mediated endocytosis is an endocytotic mechanism in which specific molecules are ingested into the cell.The specificity results from a receptor-ligand interaction.Receptors on the plasma membrane of the target tissue will specifically bind to ligands on the outside of the cell. An endocytotic process occurs and the ligand is ingested.he specificity results from a receptor-ligand interaction. Receptors on the plasma membrane of the target tissue will specifically bind to ligands on the outside of the cell. An endocytotic process occurs and the ligand is ingested.