Chase City is a town in Mecklenburg County, Virginia, United States. The population was 2,457 at the 2000 census. Tobacco and other crops are grown nearby. There is a large reservoir nearby popular with boaters and fishermen. Chase City is located at 36°47′58″N 78°27′40″W / 36.79944°N 78.46111°W / 36.79944; -78.46111 (36.799312, -78.461019). According to the United States Census Bureau, the town has a total area of 2.2 square miles (5.7 km²), all of it land.