1 The most common treatment for your home is through the use of chemicals, although there are certain types of thermal treatments. 2  On average, the bed bug treatment cost for your home can cost anywhere from $20 to $225 per treatment, depending on the type of treatment that needs to be applied to your house. The most common treatment for your home is through the use of chemicals, although there are certain types of thermal treatments. 2  On average, the bed bug treatment cost for your home can cost anywhere from $20 to $225 per treatment, depending on the type of treatment that needs to be applied to your house.