taskkill.exe is a process associated with Microsoft® Windows® Operating System from Microsoft Corporation. Non-system processes like taskkill.exe originate from software you installed on your system.Since most applications store data in your system's registry, it is likely that over time your registry suffers fragmentation and accumulates invalid entries which can affect your PC's performance.can your system now to identify unused processes that are using up valuable resources. taskkill.exe is used by 'Microsoft® Windows® Operating System'.This is an application created by 'Microsoft Corporation'. To stop taskkill.exe permanently uninstall 'Microsoft® Windows® Operating System' from your system.