Top Definition. qwertyuiopasdfghjklzxcvbnm. A phenomena that happens to a computer's keyboard when a human being is bored to death... Bored to death in a cube a human decides to type qwertyuiopasdfghjklzxcvbnm (all the keyboard buttons in an orderly way) to a search engine to see what comes up.Then finds definitions for it and then adds a new one...his phenomenon will always remain constant for data entry keyboards with the QWERTY layout (hence the name ‘QWERTY keyboards’). This is true to the same extent that that DEATH is the opposite of LIFE, yet the one can’t occur without the other since both are linked and the one always follows the other.