Overview. Vascular skin problems are often caused by issues with the vascular, or circulatory, system. The skin, also called the dermis, is one of the largest organs in the human body, and it is laced with capillaries that transport nutrients and oxygen in the blood.ngiomas are a common vascular skin condition caused by a profusion of blood vessels in the skin layers that are often called spider veins. The angiomas are created by over-development of cells that line blood vessels, states DermNetNZ.org.