Human serum albumin is the version of serum albumin found in human blood. It is the most abundant protein in human blood plasma; it constitutes about half of serum protein.It is produced in the liver. It is soluble and monomeric.he reference range for albumin concentrations in serum is approximately 35 - 50 g/L (3.5 - 5.0 g/dL). It has a serum half-life of approximately 20 days. It has a molecular mass of 66.5 kDa. The gene for albumin is located on chromosome 4 and mutations in this gene can result in anomalous proteins.