Clinicians Guide to QuantiFERON®-TB Gold Page 1 of 2. 1) What is QuantiFERON®-TB Gold? QuantiFERON®-TB Gold is an in vitro laboratory diagnostic test. using a whole blood specimen. It is an indirect test for M. tuberculosis-. complex (i.e., M. tuberculosis, M. bovis, M. africanum, M. microti, M.