Salary Overview. According to the U.S. Bureau of Labor Statistics (BLS), the average annual salary for family and general practitioners as of May 2013 was $183,940 (www.bls.gov). Most of these practitioners earned between $76,950 and $187,199 per year.f you're looking for high-paying regions to work, Hawaii was the top-paying state for family and general practitioners, offering an annual mean wage of $222,150 as of May 2013, according to the BLS. Nebraska was another top-paying state, with family practitioners earning an average yearly salary of $217,840.