Cincinnati is Ohio 's third largest city and the 25th largest city in the United States. The city sits on the border of Ohio and Kentucky at the meeting of the Ohio River and the Licking River. Cincinnati's population is slowly declining. In 2014, the population of Cincinnati is estimated at 296,000. Cincinnati has had a steadily declining population for several decades. Between 2000 and 2010, the population dropped from 331,300 to 296,900. While the worst of the decline seems to be over, Cincinnati is still steadily losing residents. In 2014, the population of Cincinnati is estimated at 296,000 with a population density of 3,810 Cincinnatians per square mile.