From Wikipedia, the free encyclopedia. In chemistry, a hydrochloride is a salt resulting, or regarded as resulting, from the reaction of hydrochloric acid with an organic base (e.g. an amine).An alternative name is chlorhydrate, which comes from French. An archaic alternative name is muriate, derived from hydrochloric acid's ancient name: muriatic acid.rom Wikipedia, the free encyclopedia. In chemistry, a hydrochloride is a salt resulting, or regarded as resulting, from the reaction of hydrochloric acid with an organic base (e.g. an amine).