Warnings. 1  Not all chameleons have the same signs to tell if it is a male or female. 2  If your chameleon is not mature then it may be hard to point out their gender.ips. 1  Look closely. 2  The bumps are small so make sure there it is or is not a female. 3  It is better to ask a professional. 4  Different species have different signs of being a male or female.