From prepping and basting to roasting and carving, get all the tips you need to cook your bird. 1  Heat oven to 350 degrees F. 2  Roast turkey uncovered for 20 minutes per pound. 3  Cook to an internal temperature of 165 degrees measured at the thigh.4  Let rest 20 minutes before carving.rom prepping and basting to roasting and carving, get all the tips you need to cook your bird. 1  Heat oven to 350 degrees F. 2  Roast turkey uncovered for 20 minutes per pound. 3  Cook to an internal temperature of 165 degrees measured at the thigh.