Postal Code Listings for Zip Code Listings for Bluffton, South Carolina (USA) What is the zip code for The following are the areas codes and zip codes for Bluffton, South Carolina ? Zip Code Listing 29909 (area code: 843) 29910 (area code: 843) Why is zip code data on an environmental science site? In 2002 I was working on a project that correlated pollution and income for zip codes across the United States. Visitors told me the data files were very useful so I left them on the site and now update the postal information on a periodic basis even though the focus of the site is conservation.