Amlodipine (as besylate, mesylate or maleate) is a medication used to lower blood pressure and prevent chest pain. It belongs to a group of medications known as dihydropyridine-type calcium channel blockers.By widening of blood vessels it lowers blood pressure.In angina, amlodipine increases blood flow to the heart muscle to relieve pain due to angina.It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.y widening of blood vessels it lowers blood pressure. In angina, amlodipine increases blood flow to the heart muscle to relieve pain due to angina. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.