Exocytosis. Photo by: Alila. Exocytosis is the cellular process in which intracellular vesicles in the cytoplasm fuse with the plasma membrane and release or secrete their contents into the extracellular space.Exocytosis can be constitutive (occurring all the time) or regulated.n response to a signal, the vesicles undergo exocytosis and release their contents. These enzymes then punch holes in the plasma membrane of the infected cell. This causes the cell to undergo self-destruction or apoptosis, also known as programmed cell death, to prevent further spread of the virus.