How much does a nurse anesthetist make? According to the Bureau of Labor Statistics, there are 34,180 nurse anesthetists employed throughout the United States. The average annual nurse anesthetist salary was $154,390, which equates to a mean hourly wage of $74.22. While the bottom ten percent in the field still earn a sizeable six-figure salary of $105,810 each year or less, the top ten percent of nurse anesthetists bring home upwards of $176,060+ annually.