Online programs offer flexibility for working nurses as well as provide an education option not available, until recently, to rurally based nurses. According to the Advance for Nurse Practitioners 2007 Salary Survey, Nurse Practitioners in Indiana made an average annual salary of $75,378.urse Practitioner Programs in Indiana. According to the Indiana Legislative Services Agency and the Indiana State Board of Nursing, APNs including Nurse practitioners must first be a licensed registered nurse in Indiana and graduate from a master's level program.