Shares & Saves. Save. Bone spicule is a term found in osteology, in dental surgery and also in ophthalmology. It is most commonly used to define the bony matrix in the formation of new bone but is also used to describe a complication in dental surgery and a symptom of an eye disease.(Andreas Rodriguez/iStock/Getty Images).he formation of new bone begins with the development of a bony matrix made up of bone spicules. These spicules are made up of networks of thin fibers with calcified deposits interwoven throughout. The fibers calcify and enclose some osteoblasts (bone-making cells) and begin to form new bone spicules.