Huntsville is a city in and the county seat of Walker County, Texas, United States. The population was 35,508 at the 2010 census. It is the center of the Huntsville micropolitan area. Huntsville is located in the East Texas Piney Woods on the Interstate 45 corridor between Houston and Dallas. Huntsville is home to Sam Houston State University, the Texas Department of Criminal Justice, Huntsville State Park, the HEARTS Veterans Museum of Texas, located on Texas Veterans Memorial Parkway at Interstate 45, and the Texas Prison Museum, also on Highway 75 near Interstate 45.