If the bruising is a reaction to treatment with prescription blood thinners, rutin may interfere with the action of the drug. Don't take rutin if you are also taking Coumadin, Plavix, Trental, or any other prescription blood thinning medication without a doctor's supervision. Selected References: Bast A, Haenen GR.ealing Hemorrhoids. 1  In addition to rutin and other citrus bioflavonoids, be sure to get enough fiber from your diet and fiber supplements. 2  If you don't eat enough fiber to stay regular now, don't start eating the recommended 30 grams of fiber a day all at once.