Review: could Humira cause Gout? Gout is found among people who take Humira, especially for people who are female, 60+ old , have been taking the drug for 1 - 6 months, also take medication Methotrexate, and have Rheumatoid arthritis . We study 199,200 people who have side effects while taking Humira from FDA and social media. Among them, 140 have Gout.