Greek Meaning: The name Sophie is a Greek baby name. In Greek the meaning of the name Sophie is: Wisdom; wise. American Meaning: The name Sophie is an American baby name.In American the meaning of the name Sophie is: Wisdom; wise. SoulUrge Number: 2. Expression Number: 9. People with this name have a deep inner desire for love and companionship, and want to work with others to achieve peace and harmony.merican Meaning: The name Sophie is an American baby name. In American the meaning of the name Sophie is: Wisdom; wise. SoulUrge Number: 2. Expression Number: 9. People with this name have a deep inner desire for love and companionship, and want to work with others to achieve peace and harmony.