Home Remedies for Fever in Adults. People can make the diagnosis of fever at home by taking a person's temperature with a thermometer. There are several ways to bring down (reduce) a fever. In general, a fever can be reduced with ibuprofen (Advil, Motrin, Nuprin) or acetaminophen (Tylenol and others).Both medications help control pain and reduce fever. Alternating doses of each will also work and prevent accidental overdose of one drug. It comes in 325 mg tablets or 500 mg tablets over the counter. 2  It may also be available in liquid formulations. 3  Again, one to two tablets every four hours should be used to eliminate a fever. 4  Like many other medications, children's doses are based on the child's weight.