Print. Share. Papain is a powerful digestive enzyme commonly found and extracted from the papaya fruit (Carica papaya) , it is also referred to as papaya proteinase. The papaya-enzyme papain plays a key role in digestive processes involving breaking down tough protein fibers.his formula contains digestive enzymes, which help digest fats (lipids), sugars, proteins, carbohydrates, gluten, fruits and vegetables, cereals, legumes, bran, nuts and seeds, soy, dairy, and all other food sources.