Xtandi (enzalutamide) is a member of the antiandrogens drug class and is commonly used for Prostate Cancer. This Xtandi price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies. The cost for Xtandi oral capsule 40 mg is around $10,367 for a supply of 120 capsules, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans. Xtandi is available as a brand name drug only, a generic version is not yet available.