There are 20-100 million sperm cells per milliliter. times. 2 - 6 milliliter per ejaculation. gives. 50 - 500 million sperm per ejaculation. Men with less than 20 million sperm cells per milliliter are considered sub fertile. More Answers: The average sperm density is reported to have dropped from 100 million per milliliter to 50 million per milliliter in the last 30-40 years. A load of ejaculate contains 40 million to 600 million sperm.