Ozone has a slightly sweet smell at very low concentrations but as the concentration increases it becomes irritating. 8. Will Ozone kill bacteria? Yes Ozone kills all bacteria and is known to be the most effective bactericide on earth. 9. Will Ozone kill(deactivate) Virus? Yes. ozone will deactivate virus by attacking the protein of the virus. 10. What about Amoeba cysts, spores and protozoans? Ozone kills all forms of amoeba spores, cysts and protozoans.