My dog has only been on prednisone for 2.5 days (approximately 5 doses) at 60 mg a dose. This was for a low platelet count in case it was autoimmune mediated. The vet has now ruled out autoimmune from lab work that has just come back and wants us to wean him off gradually by reducing the doseage in half amounts. I... show more My dog has only been on prednisone for 2.5 days (approximately 5 doses) at 60 mg a dose.