Adderall has been approved for use in patients age 3 years and older. People with even mild cases of hypertension should avoid Adderall use. Amphetamines can cause mania in people with bipolar disorder.People with a history of drug abuse need to use extreme caution when taking this medication.dderall is a mixture of four different amphetamine salts-Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, and Amphetamine Sulfate-that is used to treat Attention Deficit Hyperactivity Disorder (ADHD). Treating ADHD with Adderall was approved by the FDA in 1996.