The answer is yes. The malfunction of the peroxisomes will cause a disease called Adrenoleukodystrophy(ALD). It is a disease which caused by the accumulation of very-long chain fatty acids in tissues throughout the body.he answer is yes. The malfunction of the peroxisomes will cause a disease called Adrenoleukodystrophy(ALD). It is a disease which caused by the accumulation of very-long chain fatty acids in tissues throughout the body.