Spiros /spi-ros/ [2 sylls.] as a boys' name is of Greek and Latin origin, and the name Spiros means basket; spirit.Spiros is a variant transcription of Spiridon (Greek, Latin): from Greek spyridion.piros is an uncommon first name for men but a very popular surname for both adults and children (#69636 out of 150436, Top 46%). (2000 U.S. Census). Charted below is the baby name popularity of Spiros for boys. Spiros has yet to be ranked in the Top 1000 thus far.