Indications for FIORINAL: Tension (or muscle contraction) headache. Adult: Use lowest effective dose for shortest duration. 1–2 caps every 4hrs, as needed; max 6 caps/day. Also with Codeine: concomitant use or discontinuation of CYP2D6 inhibitors, CYP3A4 inhibitors or inducers: monitor closely and consider dose adjustments (see full labeling). Withdraw gradually by 25–50% every 2–4 days.