Average and Median Wages. The Bureau of Labor Statistics reports that medical assistants earned an average wage of $14.51 per hour as of 2011, which works out to an average salary of about $30,170 per year.The middle-earning 50 percent of medical assistants received hourly wages of between $11.86 and $16.87 an hour.The lowest-paid 10 percent of medical assistants made $10.04 or less per hour, while the highest-paid 10 percent reportedly made $19.62 or more an hour.verage and Median Wages. The Bureau of Labor Statistics reports that medical assistants earned an average wage of $14.51 per hour as of 2011, which works out to an average salary of about $30,170 per year.