The Gupta Empire (Sanskrit: गुप्तसाम्राज्य, Gupta Sāmrājya) was an ancient Indian empire, founded by Maharaja Sri Gupta, which existed at its zenith from approximately 320 to 550 CE and covered much of the Indian Subcontinent.fter the collapse of the Gupta Empire in the 6th century, India was again ruled by numerous regional kingdoms. A minor line of the Gupta clan continued to rule Magadha after the disintegration of the empire.