Vitamin D, an essential nutrient, plays a role in the production or biological activity of select hormones, and might therefore play a role in some types of hormone imbalances. Vitamin D in your body interacts with, and has an effect on the secretion of, hormones from your parathyroid glands. vitamin D deficiency can lead to the abnormal release of parathyroid hormone: since, in the absence of vitamin D, your body does not respond to parathyroid hormone, your hormone gland begins to produce very large amounts of the hormone to compensate.