1 and 2 Modern parenteral feeding regimens use lipid emulsions as a component of TPN. The globules in the lipid emulsions generally have characteristics similar to those of chylomicrons and are cleared from the blood via similar kinetics. 3. Lipid confers two major advantages.Primarily, it provides essential fatty acids, thus avoiding essential fatty acid deficiency, and secondly it is a useful energy source, providing 9 kcal/g. 4 Essential fatty acid deficiency can develop in patients who receive fat-free parenteral nutrition for longer than 2 wk. and 2 Modern parenteral feeding regimens use lipid emulsions as a component of TPN. The globules in the lipid emulsions generally have characteristics similar to those of chylomicrons and are cleared from the blood via similar kinetics. 3. Lipid confers two major advantages.