Hodgkin lymphoma, also known as Hodgkin's disease, is a type of lymphoma, a cancer of the lymphatic system.The lymphatic system is a network of nodes (knots of tissue) connected by vessels that drain fluid and waste products from the body. The lymph nodes act as tiny filters, straining out foreign organisms and cells.he two main types of lymphoma are Hodgkin lymphoma and non-Hodgkin lymphoma, which are classified by certain unique characteristics of the cancer cells. Hodgkin disease is most common in two different age groups: young adults (ages 15 to 35) and older adults (over age 50).