The list of signs and symptoms mentioned in various sources for Mbius Syndrome includes the 27 symptoms listed below: 1  Infant sucking difficulty. 2  Inability to follow moving object with eyes. 3  Lack of facial expression.  Inability to 1  smile. Tilting head back to swallow.  Sensitive eyes due to impaired squinting 1  ability. Lack of blinking.  High palate.