Nearest major airport to Live Oak, Florida: The closest major airport to Live Oak, Florida is Valdosta Regional Airport (VLD / KVLD).This airport is in Valdosta, Georgia and is 44 miles from the center of Live Oak, FL. If you're looking for domestic flights to VLD, check the airlines that fly to VLD.earest major airport to Live Oak, Florida: The closest major airport to Live Oak, Florida is Valdosta Regional Airport (VLD / KVLD).