The highest paid medical assistants can make over $19 per hour. You would make $19.62 per hour as a medical assistant if you are among the top 10 percent in earnings, according to May 2011 data from the Bureau of Labor Statistics.ou would make $19.62 per hour as a medical assistant if you are among the top 10 percent in earnings, according to May 2011 data from the Bureau of Labor Statistics.