According to the Oregon State University, in extreme case of vitamin C deficiency, a medical problem called scurvy (one kind of hair loss problems) may occur. B-Vitamins deficiencies and hair loss. Lack of B vitamins (such as B1 and B2) can lead to undernourishment of cells of hair follicles.As a result, the hair follicles cannot grow optimally and also tends to fall out easily. Vitamin B-12 is also crucial.n addition, vitamin deficiencies are one of numerous factors that can be potential to cause abnormal hair loss. However generally this factor doesn’t work alone, but typically they work together with other factors (such as other essential nutrient deficiencies, hormonal changes, and genetic trait).