What is Solodyn? Solodyn (minocycline) is a tetracycline antibiotic supplied as an extended release tablet. Solodyn is a prescription medicine used to treat pimples and red bumps (non-nodular inflammatory lesions) that happen with moderate to severe acne vulgaris in people 12 years and older. Solodyn is not effective for acne that is not red-looking (this means acne that is not inflammatory).