Registered Nurse (RN) in Phoenix, Arizona Salary. The average pay for a Registered Nurse (RN) in Phoenix, Arizona is $31.20 per hour. The highest paying skills associated with this job are Intensive Care Unit (ICU), Operating Room / OR, Recovery / Post-Anesthesia Care Unit (PACU), Emergency Room (ER), and Oncology. $41,969 - $86,376.