1 Preheat oven to 375. 2  Spray baking dish with non-stick spray. 3  Place frozen chicken breast in dish. 4  Top with sauce. 5  Bake for 45 minutes. 6  Options: Add veggies for a one dish meal. 7  If using cheese, put it on the last 2 minutes of cook time. 8  This. 9  gives it time to melt and brown if you like it that way. Spray baking dish with non-stick spray. 2  Place frozen chicken breast in dish. 3  Top with sauce. 4  Bake for 45 minutes. 5  Options: Add veggies for a one dish meal. 6  If using cheese, put it on the last 2 minutes of cook time. 7  This. 8  gives it time to melt and brown if you like it that way.