Crothersville is a town in Vernon Township, Jackson County, Indiana, United States. The population was 1,591 at the 2010 census. It was founded in 1835 and named after Dr. Crothers, a railroad superintendent. Crothersville is located at 38°47′46″N 85°50′27″W / 38.79611°N 85.84083°W / 38.79611; -85.84083 (38.796099, -85.840878). According to the United States Census Bureau, the town has a total area of 1.1 square miles (3.0 km²), all of it land.