Feelings of loneliness don’t have to be constant to call for action, but you will need to give yourself a push to get back into the thick of life and re-engage with others to start feeling better. These strategies for fighting depression and loneliness can help: 1  Make a plan.2  There are two basic types of loneliness.3  Acute loneliness results from losing a loved one or moving to a new place, for example.eelings of loneliness don’t have to be constant to call for action, but you will need to give yourself a push to get back into the thick of life and re-engage with others to start feeling better. These strategies for fighting depression and loneliness can help: 1  Make a plan.