A large precancerous polyp may lead to abdominal pain. Colon cancer is one of the deadliest types of cancer, but also one of the easiest to prevent through precancerous polyp screening.hese 10 animal facts will amaze you. A precancerous polyp, or adenoma, is a small mass of tissue found most commonly on the inside of the digestive tract. As many as half of all people have some number of these lumps in their intestine. For the most part, these lumps are benign and never become malignant.