A snake bite shot combines the warmth of smooth whiskey with refreshing citrus flavor and the fiery bite of hot sauce. Snake bite cocktails are typically served chilled with ice in a short tumbler, but a basic snake bite shot is much simpler and faster to make. If you want a cold shot without diluting the whiskey, chill the whiskey before pouring the shot. The exact measurements to make a snake bite shot depend on the volume of the shot glass, usually between 1 1/2 to 2 ounces. Things You'll Need. Fill a shot glass with whiskey, leaving only a small space at the top.