In modern times the Ganges River has become a source of life for the nearly 400 million people living in its basin. They rely on the river for their daily needs such as drinking water supplies and food and for irrigation and manufacturing. Today the Ganges River basin is the most populated river basin in the world.ourse of the Ganges River. The headwaters of the Ganges River begin high in the Himalayan Mountains where the Bhagirathi River flows out of the Gangotri Glacier in India's Uttarakhand state. The glacier sits at an elevation of 12,769 feet (3,892 m).