Those in the early stages of their career can expect to make around $29K; however, individuals with five to 10 years of experience bring in $32K on average — a distinctly larger sum. After working for 10 to 20 years, Certified Medical Assistants make a median salary of $33K. After two decades in the workforce, the average Certified Medical Assistant generally earns more than ever; median pay for this group is estimated at $36K.