Ultrasound may be used to detect many digestive problems, including: 1  Cysts or abnormal growths in the liver, spleen, or pancreas.2  Abnormal enlargement of the spleen. 3  Cancer of the liver or fatty liver. 4  Gallstones or sludge in the gallbladder.ltrasound may be used to detect many digestive problems, including: 1  Cysts or abnormal growths in the liver, spleen, or pancreas. 2  Abnormal enlargement of the spleen. 3  Cancer of the liver or fatty liver. 4  Gallstones or sludge in the gallbladder.