Begin therapy 1 to 2 days before travel to the area with malaria. Continue daily treatment for 4 weeks after leaving the area. Doryx MPC: Typical dosage: 2.4 mg/kg once daily, up to the adult dose. Begin therapy 1 to 2 days before travel to the area with malaria. Continue daily treatment for 4 weeks after leaving the area. Child dosage (ages 0–7 years)