A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA.The term frameshift mutation indicates the addition or deletion of a base pair.A point mutant is an individual that is affected by a point mutation. Repeat induced point mutations are recurring point mutations, discussed below.he term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation. Repeat induced point mutations are recurring point mutations, discussed below.