The standard of care for full-thickness burns is burn wound excision and grafting. The mortality of patients with massive burns is reduced by early tangential excision of the entire wound, followed by skin closure with an autograft from unburned areas on the patient or an allograft from a donor cadaver.urns exert a catastrophic influence on people in terms of human life, suffering, disability, and financial loss. More than an estimated 2 million people in the United States experience burn injuries, most of which are minor and cared for primarily in the ED.