Average ACT: 33. The average ACT score composite at University of Chicago is a 33. The 25th percentile ACT score is 32, and the 75th percentile ACT score is 33. In other words, a 32 places you below average, while a 33 will move you up to above average.There's no absolute ACT requirement at University of Chicago, but they really want to see at least a 32 to have a chance at being considered.he average GPA at University of Chicago is 4.23. This makes University of Chicago Extremely Competitive for GPAs. (Most schools use a weighted GPA out of 4.0, though some report an unweighted GPA.