Infarction is a medical condition in which tissue dies because the arterial blood supply is blocked. It is usually the end product of ischemia, or lowered blood supply.Infarction is most often seen with the word myocardial, indicating a heart attack.This condition occurs when one of the main cardiac arteries is blocked. When this happens, a person will often need heart bypass surgery.ou won't believe these 10 facts about people. Infarction is a medical condition in which tissue dies because the arterial blood supply is blocked. It is usually the end product of ischemia, or lowered blood supply. Infarction is most often seen with the word myocardial, indicating a heart attack.