Replicant. A replicant is a bioengineered or biorobotic being created in the film Blade Runner. The Nexus series—genetically designed by the Tyrell Corporation—are virtually identical to an adult human, but have superior strength, agility, and variable intelligence depending on the model.iktionary (0.00 / 0 votes) Rate this definition: replicant (Noun). An android that is an exact copy of a specific human, or is indistinguishable from a human. replicant (Noun). One who replies.