Typhoid can be fatal if left untreated. Typhoid can cause high fever, muscle aches, severe headache, weakness, confusion or agitation, loss of appetite, stomach pain, diarrhea or constipation, and rose-colored spots on the skin.et emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Less serious side effects include: 1  low fever; 2  headache; 3  nausea, vomiting, diarrhea, stomach pain; or. 4  mild skin rash.