The current study adds weight to the longstanding recommendation to restrict total fat and saturated fat. While adjusting for BMI eliminates the effect, this does not mean that dietary fat is not important. It is biologically plausible that high-fat diets promote weight gain, which then promotes insulin resistance. There is a large body of evidence that supports this view. In addition, there is growing evidence that obesity plays a central pathogenic role in the development of diabetes (1,2).