These symptoms may not improve with time, as they may be signs of the underlying disorder (schizophrenia or bipolar disorder). Your healthcare provider may decide to wean you off the drug slowly to avoid severe withdrawal symptoms, although this may not be necessary in all situations.Even if you are switching to another bipolar disorder or schizophrenia medication, your healthcare provider may still recommend stopping Seroquel slowly.o prevent symptoms from occurring when withdrawing from Seroquel, your healthcare provider may gradually wean you off the drug, even if switching to a different medication. Seroquel ® (quetiapine fumarate) is a prescription medication approved to treat schizophrenia or bipolar disorder.