Although C-fold and multi-fold paper towels look similar, they differ in the way they are folded. A c-fold paper towel is folded in the shape of a C, most noticeable when the towel is completely unfolded. C-fold paper towels are not interlocked, but instead they simply lie on top of each other. A multifold paper towel has a Z type fold to it. It is folded this way to allow the towels to interlock with each other. Single fold towels are paper towels that are folded in half, in one single fold.