Answers. Best Answer: Mechanism for transmitting pain is by the chemicals found in every nerve cell, called neurotransmitters. These either send or block pain messages. Serotonin is one such neurotransmitter.It blocks pain and induces a feeling of well-being. Endorphin is another neurotransmitter, a natural pain killer similar to morphine. The level of these chemicals varies between people and their production can be voluntarily increased, for example by vigorous exercise.erotonin is one such neurotransmitter. It blocks pain and induces a feeling of well-being. Endorphin is another neurotransmitter, a natural pain killer similar to morphine. The level of these chemicals varies between people and their production can be voluntarily increased, for example by vigorous exercise.