Its tuition and fees are $50,210 (2015-16). The University of Southern California’s central campus, referred to as the University Park campus, is located in Los Angeles’s Downtown Arts and Education Corridor.USC has other campuses in L.A. in addition to sites around Southern California and in Sacramento, Calif., and Washington.ummary. University of Southern California is a private institution that was founded in 1880. It has a total undergraduate enrollment of 18,740, its setting is urban, and the campus size is 226 acres. It utilizes a semester-based academic calendar.