Chromatins are just a combination of DNA, histones(a type of proteins) and RNA. Strands of DNA are considered as chromatins and when these strands combine, this forms the chromosome. Chromatin is untangled and unfolded DNA, while chromosome is condensed DNA.The chromatin condenses into chromosome during mitosis.he nucleosomes condense to form a chromatin fiber. Chromatin fiber organises into Chromosomes upon cell division. The chromatin is elaborately arranged and paired in mitosis. Sister chromatids are formed in case of meiosis along with pairing.