Oregano essential oil (Origanum vulgare) is a popular oil right now. There are countless Oregano oil health benefits being discovered every day, with uses ranging from to cooking to hospital wards. The aroma is much like you'd expect-sharp and herby.opular Uses of Oregano Essential Oil. 1  Take one drop daily to boost immunity when seasonal threats are high. 2  Rub Oregano essential oil and fractionated coconut o0il on the bottom of your feet to help boost your immune system. 3  Put one drop in place of dried Oregano in spaghetti sauce, pizza sauce, or on a roast. 4  Put 10 drops in a 16-ounce spray ...