Glucose. Glucose is a simple sugar that your body likes. Your cells use it as a primary source of energy, so when you consume glucose, it's actually helpful. When it's transported into the body, it stimulates the pancreas to produce insulin.Your brain notices this increase, understands that it's busy metabolizing what you just ate, and tells you that you're less hungry.or our purposes, high fructose corn syrup (HFCS) and sucrose are the same thing because they're both highly sweet and they both contain a large amount of fructose. Sucrose is 50% fructose and HFCS is 55% fructose (which is high compared to normal corn syrup, but pretty normal when compared to cane sugar).