Jersey is a knit fabric used predominantly for clothing manufacture. It was originally made of wool, but is now made of wool, cotton, and synthetic fibres.Since medieval times Jersey, Channel Islands, where the material was first produced, had been an important exporter of knitted goods and the fabric in wool from Jersey became well known.The fabric can be a very stretchy single knitting, usually light-weight, jersey with one flat side and one piled side.ince medieval times Jersey, Channel Islands, where the material was first produced, had been an important exporter of knitted goods and the fabric in wool from Jersey became well known. The fabric can be a very stretchy single knitting, usually light-weight, jersey with one flat side and one piled side.