If you simply write data to a USB flash drive and put it away in a safe place for 10 years, it will work again and all the data will still be there. But if you continue to use it over and over again, it will definitely wear out eventually. USB Flash Drives Have Finite Number of Write/Erase Cycles. The life expectancy of a USB Flash Drive can be measured by the number of write or erase cycles. USB flash drives can withstand between 10,000 to 100,000 write/erase cycles, depending on the memory technology used.