A positive test for ANA does not mean you have an autoimmune disease. The test finds small amounts of these antibodies in up to 15% of healthy people. Antinuclear antibodies are measured in titers.A titer above 1:160 is a positive test result. A positive result may mean: You have systemic lupus erythematosis, or SLE.About 95% of people with this autoimmune disease test positive for antinuclear antibodies. You have another type of autoimmune disease. positive test for ANA does not mean you have an autoimmune disease. The test finds small amounts of these antibodies in up to 15% of healthy people. Antinuclear antibodies are measured in titers.