Muscle fascia is the third connective tissue that affects flexibility, and by far the most important. Fascia makes up as much as 30 percent of a muscle’s total mass, and, according to studies cited in Science of Flexibility, it accounts for approximately 41 percent of a muscle’s total resistance to movement.uscle fascia is the third connective tissue that affects flexibility, and by far the most important. Fascia makes up as much as 30 percent of a muscle’s total mass, and, according to studies cited in Science of Flexibility, it accounts for approximately 41 percent of a muscle’s total resistance to movement.