Connect the included USB receiver to a USB port on your computer. Flip the Logitech wireless mouse over, and slide the power switch to the On position. Hold down the Reset button on the bottom of the mouse for four seconds to reset the mouse and refresh the wireless connection. Tips. 1  The Logitech Reconnection Utility included with your mouse may also fix connection problems.  If you continue to have connection issues, try replacing the batteries with new ones.