Sweet marjoram – has sedative properties. Helps to relieve muscle pain and spasms, stiffness, rheumatism, osteoarthritis and migraine. 3. Lavender – this is probably the most famous essential oil for pain relief and relaxation. It has anti-inflammatory, anti-microbial and sedative properties and it helps to relieve muscle tension and spasms, joint pain and headache. Lavender is also one of my top 5 essential oils for allergy relief. 4. Eucalyptus – has analgesic and anti-inflammatory properties. Good for muscle pain and nerve pain.