Wound re-epithelialization: modulating keratinocyte migration in wound healing. Raja, Sivamani K, Garcia MS, Isseroff RR. An essential feature of a healed wound is the restoration of an intact epidermal barrier through wound epithelialization, also known as re-epithelialization.aja, Sivamani K, Garcia MS, Isseroff RR. An essential feature of a healed wound is the restoration of an intact epidermal barrier through wound epithelialization, also known as re-epithelialization.