The name Natalie is a French baby name. In French the meaning of the name Natalie is: Born at Christmas. The name Natalie is an American baby name. In American the meaning of the name Natalie is: Born at Christmas. The name Natalie is a Latin baby name. In Latin the meaning of the name Natalie is: Bom at Christmas. Numerology. People with this name have a deep inner need for quiet, and a desire to understand and analyze the world they live in, and to learn the deeper truths.