The father has wings, the mother is a primate, and this child has a human soul mixed with angelic grace. ”. A Nephilim is a hybrid creature that is made up of a human soul containing traces of angelic grace. Every known Nephilim was created from the union of an angel and a human. Castiel stated that creating a Nephilim is forbidden; however, Metatron revealed in Clip Show that there was one existing on Earth.