1. Acne occurs in part when there is a buildup of dead skin cells in the pores. Salicylic acid helps normalize the shedding of the skin cells inside the pores and helps prevent the clogging that, along with oil and bacteria, can produce pimples.Salicylic acid is available in creams, lotions, and gels.. Acne occurs in part when there is a buildup of dead skin cells in the pores. Salicylic acid helps normalize the shedding of the skin cells inside the pores and helps prevent the clogging that, along with oil and bacteria, can produce pimples.