Ocean Springs, Mississippi. Ocean Springs is a city in Jackson County, Mississippi, about 2 miles (3.2 km) east of Biloxi and west of Gautier. It is part of the Pascagoula, Mississippi Metropolitan Statistical Area. The population was 17,225 at the 2000 U.S. Census. As of the 2010 U.S. Census, the city of Ocean Springs had a population of 17,442.