hepatojugular. pertaining to the liver and jugular vein. hepatojugular reflux. distention of the jugular vein induced by manual pressure over the liver; it suggests insufficiency of the right heart.sophageal reflux (gastroesophageal reflux) reflux of the stomach contents into the esophagus. hepatojugular reflux distention of the jugular vein induced by applying manual pressure over the liver; it suggests insufficiency of the right heart. intrarenal reflux reflux of urine into the renal parenchyma.