There isn't much published scientific research to support its use. MSM is also used for relief of allergies, chronic constipation, sour stomach, ulcers, a bowel disease called diverticulosis, premenstrual syndrome (PMS), mood elevation, obesity, poor circulation, high blood pressure, and high cholesterol.here isn't much published scientific research to support its use. MSM is also used for relief of allergies, chronic constipation, sour stomach, ulcers, a bowel disease called diverticulosis, premenstrual syndrome (PMS), mood elevation, obesity, poor circulation, high blood pressure, and high cholesterol.