Registered Nurse Salary. How much does a registered nurse make? Registered nurses earned a mean average wage around $72,180 or about $34.70 per hour in 2016 per bls.gov. The lowest paid 10% of employed RNs made less than $47,120 ($22.65 per hour), and the upper 10% percent made more than $102,990 ($49.52 per hour).