2 doctors weighed in: What does diffuse disc desiccation mean? 2 doctors weighed in Want a second opinion? The term is saying that multiple discs (presumably in your back/neck) are dried out and decreased in size. This happens to everyone as you age and the question is whether it is more than normal. In brief: Might be age. The term is saying that multiple discs (presumably in your back/neck) are dried out and decreased in size. 