1 These checkups will more than likely include vaccinations. 2  On average, plan on setting aside at least $100 to $200 for your dog’s first year of vaccinations. 3  Afterwards, it should cost $20 to $100 for each additional year. 4  A common, regular booster can range from $50 to $100. Other vaccinations such as Boratella, Rabies, and DHPP can range from $50 to $125. 2  These are very common vaccinations to be given out to dogs. 3  Some breeds may have to receive a Parvo vaccination. 4  The range for this vaccination varies from $50 to $150.