Traditional cured pork bacon cooked in the microwave has 25 calories per slice, while pan-frying the same product yields bacon with 42 calories per slice, according to the U.S. Department of Agriculture. The total fat per slice of microwaved bacon is 1.86 grams. The total fat in pan-fried bacon is 3.18 grams. Microwaving bacon between paper towels allows for fat absorption during the cooking process, which may account for the lower fat content of this cooking method.