1. Strep Throat. This is a bacterial infection in the throat that can make it feel sore, painful and scratchy. It may be difficult to swallow and the neck glands may become swollen. Fever, rashes, headaches, and fatigue are common.ed bumps on throat are usually associated with viral or bacterial infections, which cause many other symptoms like fever, nasal congestion, and headaches. Little red bumps on the throat should be observed carefully, especially if accompanied by sore throat and fever.