As you said, u have a blood clot, so the doctor is being careful. Duphaston is usually prescribed for women, who have pcod, spotting, difficult pregnancy, chances of miscarriage, during the first trimester. The leaflet will give a lot of side effects but it's not necessary that any or all of it should apply to you.It's a disclaimer for the pharmaceutical companies.s you said, u have a blood clot, so the doctor is being careful. Duphaston is usually prescribed for women, who have pcod, spotting, difficult pregnancy, chances of miscarriage, during the first trimester. The leaflet will give a lot of side effects but it's not necessary that any or all of it should apply to you.