Endospores are thick-coated, resistant cells produced within a bacterial cell that has been exposed to harsh conditions. Endospores are inert and can endure extreme conditions like radiation, heat and cold, absence of nutrients and water. When conditions are good, they produce vegetative cells and thrive.When condition turn unfavorable, endospores are produced again and they remain inert. Vegetative cells are any cells of plants or animals that do not participate in reproduction. These are vulnerable to external changes and react easily.ndospores are inert and can endure extreme conditions like radiation, heat and cold, absence of nutrients and water. When conditions are good, they produce vegetative cells and thrive. When condition turn unfavorable, endospores are produced again and they remain inert.