1 Cultured Nutrients-Cultured vitamins are synthetic isolates that are cultured in a blend of nutritional yeast, S. cerevisiae being the most common, and other vital nutrients. 2  These nutrients are frequently misbranded and marketed as whole-food vitamins. Cultured nutrients-Vitamins created by culturing vitamin and mineral isolates in nutritional yeast and/or probiotics. 2  Whole-food nutrients-Full-spectrum vitamins and their co-factors extracted from natural food sources (e.g. herbs, fruits, spices, & vegetables).