Uses of poloxamer 407 [edit]. Most of the common uses of poloxamer 407 are related to its surfactant properties. For example, it is widely used in cosmetics for dissolving oily ingredients in water.It can also be found in multi-purpose contact lens cleaning solutions, where its purpose there is to help remove lipid films from the lens.ost of the common uses of poloxamer 407 are related to its surfactant properties. For example, it is widely used in cosmetics for dissolving oily ingredients in water. It can also be found in multi-purpose contact lens cleaning solutions, where its purpose there is to help remove lipid films from the lens.