Distance from San Diego, CA to Denver, CO. The total distance from San Diego, CA to Denver, CO is 834 miles. This is equivalent to 1 341 kilometers or 724 nautical miles. Your trip begins in San Diego, California. It ends in Denver, Colorado. Your flight direction from San Diego, CA to Denver, CO is Northeast (51 degrees from North). The distance calculator helps you figure out how far it is to fly from San Diego, CA to Denver, CO. It does this by computing the straight line flying distance (as the crow flies).