Calorie Breakdown. A slice of fast-food cheese pizza weighing approximately 103 g contains 272 calories, 33.56 g of carbohydrate, 12.27 g of protein, 9.8 g of fat, 4.35 g of saturated fat, 1.8 g of fiber, 551 mg of sodium and 22 mg of cholesterol, notes the U.S. Department of Agriculture's National Nutrient Database.