Streptomyces is a genus of Gram-positive bacteria that grows in various environments, and its shape resembles filamentous fungi.The morphological differentiation of Streptomyces involves the formation of a layer of hyphae that can differentiate into a chain of spores. In some Streptomyces, secondary metabolism and differentiation can be related. Phylogenetically, Streptomyces are a part of Actinobacteria, a group of Gram-positives whose genetic material (DNA) is GC-rich (70%) when compared with other bacteria such as Escherichia coli (50%).