Walgreens will be open per usual on Thanksgiving Day, and 24-hour locations will have the same hours. Non-24 hour Walgreens stores are open 8 a.m. to 10 p.m. Their pharmacies will also be open Thanksgiving Day, and the same goes for the 24-hour pharmacies. On Black Friday, they will operate under normal business hours. CVS stores are open Thanksgiving Day, while the 24-hour locations will have the same hours.