RN and LPN: two different sets of initials on different name badges – and often two very different roles. Registered nurses (RN) have, at the minimum, a two-year degree or three-year diploma. Many have baccalaureate degrees.icensed practical nurses (LPN) have about a year of nursing education, often culminating in a certificate. A minority complete longer programs and walk away with a degree – often an Associate of Applied Science (AAS). Find an LPN or LVN program in your state. The role of an LPN is, as the name suggests, practical.