Rabies postexposure vaccinations consists of a dose of human rabies immune globulin and four doses of rabies vaccine given on the day of the exposure, and then again on days 3, 7, and 14.The vaccine is given in a muscle, usually in the upper arm.his set of vaccinations is highly effective at preventing rabies if given as soon as possible following an exposure. If a person has previously received postexposure vaccinations or received preexposure vaccinations, only two doses of vaccine (on the day of exposure and then 3 days later) are needed.