Cranial Nerve V: The Trigeminal Nerve Stemming from the lateral superior margin of the left and right side of the pons, this nerve branches into three: V/I ophthalmic, V/II maxillary and V/III mandibular nerves. These branches exit the skull through the superior orbital fissure (V/I), the foramen rotundum (V/II) and the foramen ovale (V/III). This nerve governs the sensory innervation of the face, sinuses and teeth.