It is painful when the organs stop working. That is why the key to a relatively peaceful death is pain killers. I saw my grandfather die. He too had Alzheimer's and was a very moral and good man. However, as his body shut down and his organs failed, no amount of his good deeds on earth could ameliorate his pain.t is a release. There may be pain associated with the cause of death, depending upon the cause. But death itself is a painless letting go. At the time of death the body produces endorphins which actually produce a feeling of happiness, or even euphoria.