Driving distance from Mobile, AL to Baton Rouge, LA. The total driving distance from Mobile, AL to Baton Rouge, LA is 200 miles or 322 kilometers. Your trip begins in Mobile, Alabama. It ends in Baton Rouge, Louisiana. If you are planning a road trip, you might also want to calculate the total driving time from Mobile, AL to Baton Rouge, LA so you can see when you'll arrive at your destination.