Minneapolis (/ˌmɪniˈæpəlɪs/) is the county seat of Hennepin County, and the larger of the Twin Cities, the 16th-largest metropolitan area in the United States. As of 2015, Minneapolis is the largest city in the state of Minnesota and 46th-largest in the United States with a population of 410,939. Minneapolis and Saint Paul anchor the second-largest economic center in the Midwest, after Chicago.