The cost to change a flight depends greatly on the airline that you have purchased your ticket from. Airlines have “penalty fees” that can range from $0 to $400.00 (yowza!) to make a change to your ticket.For domestic flights, most airlines charge around $200.But the penalty is not the whole story.t the time you make the change, the great $250 fare is gone and flights on the new dates are selling for $375. To switch to that flight, Delta would charge a $200 change fee, plus another $125 for the fare difference ($375 minus $250). So the change you want to make would cost $325 total.