Grafton is a town in Worcester County, Massachusetts, United States. The population, indicated by the 2014 town records is 14, 268, in nearly 5,700 households. Incorporated in 1735, Grafton is the home of a Nipmuc village known as Hassanamisco Reservation, the Willard House and Clock Museum, Community Harvest Project, and the Tufts University Cummings School of Veterinary Medicine.