The ________ of a phospholipid molecule will seek water, whereas the ________ of the molecules will avoid water. Answer a. tail; head b. head; tail c. hydrophobic portion; hydrophilic portion d. fatty acid; phosphate group.Follow. 3 answers 3..head; tail hydrophobic tails and a hydrophilic head. It is usually found with cholesterol molecules which are found in-between the spaces of the phospholipid.