Get emergency medical help if you or your child experiences any of those symptoms. In very rare cases, children who receive the DTaP vaccine may experience seizures, coma or permanent brain damage. Other serious side effects of the DTaP vaccine may include seizures, high fever or vomiting. In rare cases, the Tdap, Td and DT vaccines may cause severe swelling and pain where the injection was given. More common side effects of all four types of tetanus vaccine include: mild fever, mild pain, nausea, diarrhea, headaches and tiredness. Pain, swelling or redness may occur in the location where the injection was given.