A: Abilify (aripiprazole) is a medication that is used to treat bipolar disorder, schizophrenia, and depression. It is in a group of medications called atypical antipsychotic medications that work on chemicals in the brain that may be elevated causing your symptoms.: Abilify (aripiprazole) (http://www.everydayhealth.com/drugs/abilify) is an antipsychotic that works on chemicals in the brain. Abilify is indicated for schizophrenia and bipolar disorder. Abilify also can be used for mood disorder such as mood swings, temper tantrums and aggression.