It is caused by a defect in the micro tubules of the Golgi Apparatus. This terrible disease is not the only disease that the Golgi Apparatus can cause. The Golgi can cause many other terrible disease such as Alzheimer's which is an age-related, non-reversible brain disorder.his terrible disease is not the only disease that the Golgi Apparatus can cause. The Golgi can cause many other terrible disease such as Alzheimer's which is an age-related, non-reversible brain disorder.