Rating Newest Oldest. Best Answer: The foundations of the endocrine system are the hormones and glands. As the body's chemical messengers, hormones (pronounced: hor-moanz) transfer information and instructions from one set of cells to another. Many different hormones move through the bloodstream, but each type of hormone is designed to affect only certain cells. Source(s): http://www.kidshealth.org/teen/your_body...