Without this treatment, anyone who is exposed to rabies will almost certainly die. There is no cure for rabies once symptoms develop. If you think you may have been exposed to rabies, apply first aid to the wound and seek medical treatment immediately. Symptoms in humans can include: 1  Irritability. 2  Headache. 3  Fever. 4  Sometimes itching or pain at the site of exposure. 5  Paralysis. 6  Convulsions. 7  Death.