1 The good news is that Diatomaceous Earth is non-toxic to humans and animals; it is even used in some foods food (food-grade quality, not the DE used for pool filtration systems) and some health supplements.2  DE is also used for a variety of beauty and health care products. The good news is that Diatomaceous Earth is non-toxic to humans and animals; it is even used in some foods food (food-grade quality, not the DE used for pool filtration systems) and some health supplements.