Edentulous refers to the quality of having no teeth, or few teeth. In humans, tooth loss is usually due to disease, accident, the aging process, or dental decay.Some animals, however, are meant to be edentulous, such as anteaters, sloths, aardvarks, and other members of the Xenartha, or former Edentata, order.eople missing teeth may also have trouble pronouncing English letter sounds such as “f” or “v,” which require the lips to touch the teeth. Tooth loss can also pose patients with difficulty chewing. Ad. Teeth also perform several roles in maintaining the structural integrity of the face.