Indiscriminate use of oral corticosteroids in an unsupervised manner may lead to steroid-dependence as well as increased risk of side effects. Even small doses of oral corticosteroids can produce serious side effects when used on a long term daily basis.Although there are many dosage schedules for short term oral corticosteroid treatment, a typical short term burst-dosage schedule for an adult might look like this: Day 1 40mg of prednisone.Day 2 30mg of prednisone. Day 3 20mg of prednisone.ral corticosteroids are sometimes also used to treat sinusitis or severe allergies. Corticosteroids decrease inflammation in the sinuses and nose. They are actually the most effective anti-inflammatory medications available.