Men entering midlife commonly experience an enlarged prostate, which can restrict the flow of urine from the bladder and lead to such problems as frequent urination, urine leakage and urinary tract infections. Here are 10 natural remedies for men to treat an enlarged prostate: 1. Eat pumpkin seeds. The crunchy snacks contain protective compounds called phytosterols, which may be responsible for shrinking the prostate, according to Prevention. They also contain chemicals that may be beneficial for prostate health.