How Much Does a Nurse Anesthetist Make. The average annual nurse anesthetist salary is $157,690. The average salary is calculated by adding all the wages within the occupation and dividing that value by the total number of employees. The lowest 10% of nurse anesthetist salaries are less than $106,010 annually.The top 10% of nurse anesthetist salaries reach more than $210,000 per year.he average salary is calculated by adding all the wages within the occupation and dividing that value by the total number of employees. The lowest 10% of nurse anesthetist salaries are less than $106,010 annually. The top 10% of nurse anesthetist salaries reach more than $210,000 per year.