A standard “drink” is 0.6 ounces of pure alcohol. When inside an actual glass, this looks like: Alcohol can be detected in urine, blood, saliva, sweat, breath, and even your hair follicles. So if you have one glass of wine (5 fluid ounces), your liver will be able to metabolize it in about one hour. But it you have two shots of vodka one after the other, it will take two hours to get sober again.