Povidone-iodine applied to an abrasion using a cotton swab. Povidone-iodine is a broad spectrum antiseptic for topical application in the treatment and prevention of infection in wounds.May be used in first aid for minor cuts, grazes, burns, abrasions and blisters.ovidone-iodine is a broad spectrum antiseptic for topical application in the treatment and prevention of infection in wounds. May be used in first aid for minor cuts, grazes, burns, abrasions and blisters.