Advance Practice Registered Nurses in the United States take home an average $87K annually. Geography is the biggest factor affecting pay for this group, followed by years of experience. Not all workers are lucky enough to have benefits; in fact, one-fourth are without coverage.he average pay reported by folks with 10 to 20 years of experience is around $92K. Respondents who boast more than 20 years of experience can't seem to boast paychecks reflecting that extensive experience, though; veteran Advance Practice Registered Nurses report making only $90K on average.