Report Abuse. The lasagna recipe I use calls for a 375 degree oven for about 45 minutes covered with foil. Then, take the foil off, and put back in the oven for another 10-15 minutes. A good indicator that your lasagna is done is that you can see the sauce simmering in the dish (that is, if you use a glass dish).If you're not using no-bake noodles, then cook them al dente (firm) before putting them in the oven.ake your lasagna at 350 degrees F for 30 minutes or until the cheese is all melted and bubbly. Cook your lasagna noodles until they are al dente before assembling the lasagna and baking it. SAC. Wedge-The Envy of all Corellia · 8 years ago.