Related Galleries / Refresh Gallery. The 2014 Liberty Mutual Workplace Safety Index found that the most disabling workplace injuries and illnesses in 2012 amounted to nearly $60 billion in direct U.S. workers’ compensation costs. That’s right: $60 billion in direct costs to U.S. businesses. U.S. businesses spend more than $1 billion a week on the most disabling workplace injuries according to the 2014 Liberty Mutual Workplace Safety Index.