My guess is that the markup is around 50%. Botox and Juvederm are actually low margin products for the plastic surgeons. Let me break it down for you. One vial of Botox, which contains 100 units, typically sell for ~ $500 dollars to Physicians. Because the physicians have to reconstitute Botox from powder to liquid form, they typically can't get all 100 units out. They'll lose ~ 10 units from reconstitution.