Nearest major airport to Jackson, Mississippi: The closest major airport to Jackson, Mississippi is Jackson-Medgar Wiley Evers International Airport (JAN / KJAN). This airport is 12 miles from the center of Jackson, MS. If you're looking for domestic flights to JAN, check the airlines that fly to JAN. Search for direct flights from your hometown and find hotels near Jackson, MS, or scroll down for more international airports or domestic airports. You can also browse local airports if you're a pilot.