If you go long enough without sleep, you may begin to have hallucinations. Read more. The long-term effects of sleep deprivation include anxiety, depression, and even thoughts of suicide. Read more.If you are seriously sleep deprived, you might fall asleep for short periods without even knowing it.ack of sleep can actually increase your appetite, and your brain may not get the message that you’ve had enough to eat. Read more. Lack of sleep affects the amount of insulin released after you eat, increasing your risk of developing type 2 diabetes. Read more.