Incruse Ellipta: Umeclidinium belongs to the class of medications called long-acting muscarinic antagonists (LAMA). It is used to reduce the symptoms of chronic obstructive pulmonary disease (COPD) including chronic bronchitis and emphysema. Umeclidinium works by relaxing the muscles in the walls of the small airways in the lungs. This allows the airways to open and makes it easier for air to move in and out of the lungs.