Totana is a municipality in the Region of Murcia in Spain. It has a population of 30,850. The local economy is largely dependent on agriculture and related industries. it has a railway station providing a service on the Cercanías Murcia/Alicante commuter line, providing connections to Alicante and Murcia. ( 1 Spanish) Totana. ( 2 Spanish) Council of Totana. 3  Realtime weather data from Totana.  Totana's web 1  portal. Totana. Encyclopædia Britannica (11th ed.).