Illustration depicting ovulation and fertilization. Human fertilization is the union of a human egg and sperm, usually occurring in the ampulla of the uterine tube. The result of this union is the production of a zygote cell, or fertilized egg, initiating prenatal development.Scientists discovered the dynamics of human fertilization in the nineteenth century.The process of fertilization involves a sperm fusing with an ovum.he result of this union is the production of a zygote cell, or fertilized egg, initiating prenatal development. Scientists discovered the dynamics of human fertilization in the nineteenth century. The process of fertilization involves a sperm fusing with an ovum.