Meaning of Uwe. German name. In German, the name Uwe means-universal ruler.The name Uwe originated as an German name. The name Uwe is most often used as a boy name or male name.German Name Meaning-universal ruler. Origin-Germany.erman name. In German, the name Uwe means-universal ruler.The name Uwe originated as an German name. The name Uwe is most often used as a boy name or male name. German Name Meaning-universal ruler. Origin-Germany.