Esophageal spasms + anal spasms. I never associated the esophageal throat spasms or anal spasms that I have very infrequently with this condition. But evidently both can be symptoms of Crohns. Wow, are they ever painful! Kind of feels like a muscle cramp [Charley-Horse] in the calf of a leg only in my throat or rectum. Intense. but doesn't last long.