Confidence votes 94.7K. The Bubonic Plague originated in China. It was spread by the fleas carried by rats going aboard ships and they were transported to Italy, Greece and France, when the rats left the ships entering cities and gave us the Bubonic Plague.he Bubonic Plague spread from China and East Asia to Europe through the Silk Road and arrived in the Ukraine. It also spread from fleas upon rats aboard merchant ships, and i … s believed to have spread from Sicily. From both these places, the disease spread enormously and claimed over half of the population of Europe.