Brand names for doxycycline include Vibramycin, Oracea, Doryx, and Adoxa. This doxycycline price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies. The cost for doxycycline capsule hyclate 50 mg is around $15 for a supply of 20 capsules, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans. hyclate 50 mg doxycycline capsule. from $15.20 for 20 capsule.