Freebase(0.00 / 0 votes)Rate this definition: Offspring. In biology, offspring is the product of reproduction, of a new organism produced by one or more parents. Collective offspring may be known as a brood or progeny in a more general way. This can refer to a set of simultaneous offspring, such as the chicks hatched from one clutch of eggs, or to all the offspring, as with the honeybee. Human offspring are referred to as children; male children are sons and female children are daughters. See kinship and descent.