1 Nausea and vomiting. 2  Insomnia. 3  Symptoms of schizophrenia (such as hallucinations or delusions). 4  Bipolar disorder symptoms (such as mania or depression).o prevent symptoms from occurring when withdrawing from Seroquel, your healthcare provider may gradually wean you off the drug, even if switching to a different medication. Seroquel ® (quetiapine fumarate) is a prescription medication approved to treat schizophrenia or bipolar disorder.