Low heat allows the meat to cook slowly, which results in an excellent outer crust without burning or the meat becoming dry. The best temperature for brisket cooked on a grill is around 225°F (about 107°C) to 250°F (about 121°C), though cooking on a grill or in a smoker can be done as low as about 210°F (about 99°C). In an oven, the temperature can be set higher, to around 250°F (about 121°C) or 300°F (about 149°C).