Average ACT: 22. The average ACT score composite at IUPUI is a 22. The 25th percentile ACT score is 19, and the 75th percentile ACT score is 25. In other words, a 19 places you below average, while a 25 will move you up to above average.he average GPA at IUPUI is 3.33. This makes IUPUI Moderately Competitive for GPAs. (Most schools use a weighted GPA out of 4.0, though some report an unweighted GPA. With a GPA of 3.33, IUPUI accepts below-average students.