You may think of cruises as something reserved for Alaska or the Caribbean. In fact, you can cruise along the U.S. East Coast and see a good portion of the country's coastal cities, as well as a few foreign ones. Whether you want to cruise for a few days or more than a week, several cruise lines offer tours of the country's coast. Maine Coast and Harbors. The Maine Coast and Harbors cruise is brought to you by American Cruise Lines. This eight-day, seven-night cruise brings you along the dramatic Maine coastline and into the state's harbors and ports.