The first stage of gene expression is known as transcription. This is the process by which RNA Polymerase, along with other transcription factors, reads and transcribes the DN … A sequence into a complementary RNA strand.3 people found this useful.he two main steps in gene expression are transcription and translation. In eukaryote cells transcription occurs in the nucleus, and translation occurs in the cytoplasm. 1 person found this useful. Edit.