Answer by Hyllary. Confidence votes 247. Rawhide is made from the skin of animals, usually cow. The skin is split into inner and outer layers. The tough outer layer is used for leather shoes, garments, and upholstery, while the softer inner layer is cut and formed into different shapes for dog chews.ones are made from calcium. A typical bone has an outer layer of hard or compact bone, which is very strong, dense and tough. Inside this is a layer of spongy bone, which is … like honeycomb, lighter and slightly flexible.