Fructification. 1. The act of forming or producing fruit; the act of fructifying, or rendering productive of fruit; fecundation. The prevalent fructification of plants. (Sir t. Brown) 2. (Science: botany) The collective organs by which a plant produces its fruit, or seeds, or reproductive spores. The process of producing fruit, or seeds, or spores. Origin: L. Fructificatio: cf. F. Fructification.