Drysol is a solution for HYPERHIDROSIS (excessive sweating): If you have tried several different kinds of over-the-counter antiperspirants without success, Drysol is your solution. Drysol is a prescription strength medication in USA which is commonly prescribed for excessive sweating. A fairly common problem, excessive sweating can be limited to the armpits, but often affects the palms and soles of the feet as well.