Dilantin Uses. Certain types of epileptic seizures can be controlled with Dilantin. Uses of the drug specifically include the treatment of generalized tonic-clonic seizures, complex partial seizures, and seizures during brain surgery. On occasion, Dilantin may be used for something other than the conditions listed above. Among these potential off-label Dilantin uses are the treatment of nerve pain, irregular heart rhythms, and migraines. The medication is approved for use in both adults and children.