NP Programs are pricey. Most nurse practitioner programs require students to complete 30-54 credits (an average of about 45) depending on program and specialty. In-State tuition can cost anywhere from $225 to $665 per credit with an average of around $400 a credit for schools we surveyed.nline programs run somewhere in between costing $400-$800 per credit ultimately averaging about $22,500 for a nurse practitioner degree. Private universities cost anywhere from $500 to $1,500 per credit. If you attend one of these institutions you can expect to pay about $45,000 or more for your NP program.