Parkinson's disease symptoms and signs may vary from person to person. Early signs may be mild and may go unnoticed. Symptoms often begin on one side of your body and usually remain worse on that side, even after symptoms begin to affect both sides.Parkinson's signs and symptoms may include: 1  Tremor. 2  A tremor, or shaking, usually begins in a limb, often your hand or fingers.ymptoms often begin on one side of your body and usually remain worse on that side, even after symptoms begin to affect both sides. Parkinson's signs and symptoms may include: 1  Tremor.