Changes to the epigenome can result in changes to the structure of chromatin and changes to the function of the genome.The epigenome is involved in regulating gene expression, development, tissue differentiation, and suppression of transposable elements.Unlike the underlying genome which is largely static within an individual, the epigenome can be dynamically altered by environmental conditions.he epigenome is involved in regulating gene expression, development, tissue differentiation, and suppression of transposable elements.