Introduction (Back to Top) The human bot fly, Dermatobia hominis (Linnaeus Jr., 1781), is a large, densely haired fly that looks like a bumblebee (Kahn 1999). The human bot fly is native to Central and South America. The fly is not known to transmit disease-causing pathogens, but the larvae of D. hominis will infest the skin of mammals and live out the larval stage in the subcutaneous layer, causing painful pustules that secrete fluids.