Top 200 Highest Paying Jobs in North Carolina. The top 200 highest paying jobs in North Carolina (ranked by annual average salary) are listed in Table 1. The entry level salary (as measured by the salary of the lowest 10% paid workers) and the number of employment of each job in North Carolina are also shown. We note from the table that the highest paying profession in North Carolina is general pediatricians with an average annual salary of $183,270. The second highest paying job is other specialist dentist (average salary $170,800). The salary and the employment information in North Carolina is computed from data published by U.S. Bureau of Labor Statistics in May 2015 [1].