Conclusion. Ensure is a popular nutritional supplement that is used to replace a normal meal, but as a dietary supplement may not provide enough benefits for dieters. Still, it does come in a variety of palatable flavors that may help dieters for short term support.nsure is a meal replacement drink designed to provide nutrition and prevent hunger by offering a nutrient-fortified shake, now available in various flavors and five different shakes for a dieter’s individual needs.