Common advice ranges from LifeSpan’s recommendation for lubricating your treadmill every 40 hours of use, or 3 months, whichever comes first, to Steelcase’s counsel that once a year is good enough if the treadmill is used under 10 hours per week or twice a year if it’s used over 10 hours per week.eep in mind that you’ll want to warm up the treadmill board by walking on it for 20 minutes before applying the wax. While most every treadmill desk vendor supplies their house brand of silicone spray lubricant (with the odd exception of TreadDesk) they’re all basically the same 100% silicone solution.