A Test Variable(s): The dependent variable(s). This is the continuous variable whose means will be compared between the two groups. You may run multiple t tests simultaneously by selecting more than one test variable. B Grouping Variable: The independent variable.unning the Test. To run the Independent Samples t Test: 1  Click. 2  Move the variable. 3  to the Grouping Variable field, and move the variable. 4  to the Test Variable(s) area. 5  Now. 6  is defined as the independent variable and. 7  is defined as the dependent variable. 8  Click Define Groups, which opens a new window.