Risk factors for duodenal ulcer disease. Abu Farsakh NA. OBJECTIVE: To evaluate the role played by some of the traditional risk factors on the prevalence of duodenal ulcer disease in Jordan, where the prevalence of Helicobacter pylori is high.ONCLUSION: Many factors are important in the predisposition for ulcer disease in subjects with Helicobacter pylori. Modification of these factors would be essential to decrease the prevalence of ulcer disease and will result in large economic and medical savings.