High blood pressure (hypertension) High blood pressure is the excessive force of blood pumping through your blood vessels. High blood pressure causes many types of cardiovascular disease, such as stroke and heart failure, and renal disease.Peripheral arterial disease Peripheral arterial disease (PAD) is caused by atherosclerosis, which is the narrowing and / or blockage of the blood vessels in the legs.igh blood pressure (hypertension) High blood pressure is the excessive force of blood pumping through your blood vessels. High blood pressure causes many types of cardiovascular disease, such as stroke and heart failure, and renal disease.