Variability. It is often said that sperm take three months to regenerate, but 74 days is only two and a half months. Still, this may be to account for individual differences.ffects. Since sperm are also cells of the body, they receive the same nutrients and toxins that are put into the body. If a man is taking care of himself, eating properly, not smoking or using drugs and getting the right vitamins, his sperm will most likely be healthy, unless there is some kind of underlying problem.