Some are prescribed with bronchodilators because these two medications can work together to make breathing more effective. Fluticasone (Flovent), budesonide (Pulmicort), and prednisolone are the ones doctors commonly prescribe for COPD. 1  Fluticasone comes as an inhaler that you use once or twice daily. 2  Some people report headaches, sore throat, a change in their voice, and allergic reactions.