Cairo, GA. Online Offers. Cairo (i/keɪ.roʊ/; named for Cairo, Egypt, but pronounced differently) is a city in Grady County, Georgia, United States. As of the 2000 census, the city had a total population of 9,239. The city is the county seat of Grady County. Although Cairo is nicknamed the Syrup City it has no relationship with the Karo brand of syrup, which is pronounced like the city's name.