A: All girls and boys who are 11 or 12 years old should get the recommended series of HPV vaccine. The vaccination series can be started at age 9 years. Teen boys and girls who did not get vaccinated when they were younger should get it now. HPV vaccine is recommended for young women through age 26, and young men through age 21. HPV vaccine is also recommended for the following people, if they did not get vaccinated when they were younger: 1  young men who have sex with men, including young men who identify as gay or bisexual or who intend to have sex with men through age 26; 2  young adults who are transgender through age 26; and.