Prevagen (Pronounced: prev-uh-gen) is a new brain health supplement and functions unlike other brain or memory supplements.* Prevagen’s patented ingredient is a new use for a well-known protein called “apoaequorin” which was originally found in a certain species of jellyfish.he main ingredient in Prevagen® is “ apoaequorin ”, which was originally discovered in jellyfish. Prevagen® is now made in a controlled scientific process developed by university researchers and scientists in Madison, Wisconsin.