▁ 5 ▁is ▁a ▁protein ▁that ▁in ▁humans ▁is ▁encoded ▁by ▁the ▁R BB P 5 ▁gene . ▁ ▁Function ▁▁ ▁The ▁protein ▁encoded ▁by ▁this ▁gene ▁is ▁a ▁u bi quit ously ▁expressed ▁nuclear ▁protein ▁and ▁belongs ▁to ▁a ▁highly ▁conser ved ▁sub family ▁of ▁W D - repeat ▁prote ins . ▁It ▁is ▁found ▁among ▁several ▁prote ins ▁that ▁bind ▁directly ▁to ▁ret in ob last oma ▁protein , ▁which ▁regul ates ▁cell ▁pro l ifer ation . ▁The ▁encoded ▁protein ▁interact s ▁prefer entially ▁with ▁the ▁under ph osph ory l ated ▁ret in ob last oma ▁protein ▁via ▁the ▁E 1 A - binding ▁pocket ▁B . ▁ ▁Inter actions ▁▁ ▁R BB P 5 ▁has ▁been ▁shown ▁to ▁interact ▁with : ▁ ▁AS CL 2 , ▁ ▁M LL , ▁ ▁M LL 3 , ▁ ▁and ▁ ▁N CO A 6 . ▁ ▁References ▁ ▁Further ▁reading <0x0A> </s> ▁Vincent ▁Henry ▁Cart w right ▁D SO ▁( 1 0 ▁September ▁ 1 8 8 2 ▁– ▁ 2 5 ▁November ▁ 1 9 6 5 ) ▁was ▁an ▁English ▁rugby ▁union ▁international ▁who ▁capt ained ▁his ▁country . ▁He ▁also ▁played ▁first - class ▁cr icket ▁for ▁Not ting ham shire . ▁ ▁Personal ▁history ▁Cart w right ▁was ▁born ▁in ▁ 1 8 8 2 ▁in ▁Not ting ham . ▁He ▁was ▁educated ▁Rugby ▁before ▁mat ric ulating ▁to ▁Oxford ▁University ▁in ▁ 1 9 0 1 . ▁After ▁leaving ▁university ▁he ▁became ▁a ▁solic itor