▁ser at rod ast ▁does ▁not ▁affect ▁th rom bus ▁formation , ▁time ▁to ▁occ l usion ▁and ▁ble eding ▁time . ▁Ser at rod ast ▁has ▁no ▁effect ▁on ▁pro th rom bin ▁time ▁and ▁activ ated ▁partial ▁th rom b op last in ▁time , ▁thus ▁r uling ▁out ▁any ▁action ▁on ▁blood ▁co ag ulation ▁cas cade . ▁ ▁Medical ▁uses ▁Ser at rod ast ▁is ▁used ▁to ▁treat ▁ast h ma . ▁ ▁There ▁are ▁no ▁ade qu ate ▁and ▁well - control led ▁studies ▁of ▁ser at rod ast ▁in ▁pre gn ant ▁women . ▁The ▁drug ▁should ▁be ▁used ▁in ▁pre gn ancy ▁only ▁if ▁the ▁potential ▁benefits ▁justify ▁the ▁risk ▁to ▁the ▁fet us . ▁Ser at rod ast ▁should ▁not ▁be ▁used ▁during ▁la ct ation . ▁ ▁The ▁safety ▁and ▁effic acy ▁of ▁ser at rod ast ▁has ▁not ▁been ▁established ▁in ▁children ▁( < 1 8 ▁years ▁of ▁age ). ▁ ▁Cont ra ind ic ations ▁and ▁interactions ▁Ser at rod ast ▁should ▁not ▁be ▁used ▁in ▁people ▁with ▁li ver ▁disease . ▁ ▁Use ▁with ▁par ac et am ol ▁or ▁with ▁ce ph em ▁ant ib iot ics ▁increases ▁the ▁risk ▁of ▁li ver ▁damage . ▁ ▁Use ▁with ▁asp ir in ▁increases ▁the ▁bio av ail ability ▁of ▁ser at rod ast . ▁ ▁Ad verse ▁effects ▁The ▁most ▁frequently ▁observed ▁( 0 . 1 ▁to ▁ 5 %) ▁ad verse ▁re actions ▁include ▁elev ated ▁trans amin ases ,