▁provide ▁stable ▁binding . ▁This ▁problem ▁can ▁be ▁solved ▁by ▁using ▁mult imer ized ▁M HC - ep it op es , ▁which ▁increases ▁the ▁binding ▁av id ity ▁and ▁therefore ▁allows ▁stable ▁binding . ▁Fl u or och rom es ▁conjug ated ▁to ▁the ▁M HC - mult im ers ▁then ▁can ▁be ▁used ▁for ▁identification ▁of ▁T ▁cells ▁by ▁flow ▁c yt ometry . ▁Now ad ays , ▁M HC ▁mole cules ▁can ▁be ▁produced ▁recom bin antly ▁together ▁with ▁the ▁ant igen ic ▁pe pt ides ▁which ▁are ▁known ▁for ▁a ▁fast - g row ing ▁number ▁of ▁dise ases . ▁ ▁The ▁Stre pt amer ▁technology ▁ ▁The ▁Stre pt amer ▁back bone ▁The ▁Stre pt amer ▁st aining ▁principle ▁comb ines ▁the ▁classic ▁method ▁of ▁T ▁cell ▁isol ation ▁by ▁M HC - mult im ers ▁with ▁the ▁St rep - tag / St rep - T act in ▁technology . ▁The ▁St rep - tag ▁is ▁a ▁short ▁pe pt ide ▁sequence ▁that ▁displays ▁moder ate ▁binding ▁aff inity ▁for ▁the ▁bi ot in - binding ▁site ▁of ▁a ▁mut ated ▁stre pt avid in ▁mole c ule , ▁called ▁St rep - T act in . ▁For ▁the ▁Stre pt amer ▁technology , ▁the ▁St rep - T act in ▁mole cules ▁are ▁mult imer ized ▁and ▁form ▁the ▁" back bone ", ▁thus ▁creating ▁a ▁platform ▁for ▁binding ▁to ▁st rep - tag ged ▁prote ins . ▁Further , ▁the ▁St rep - T act