▁review ed . ▁Mult if ocal ▁su pr at ent orial ▁les ions ▁were ▁present ▁in ▁all ▁patients . ▁Most ▁les ions ▁were ▁small ▁( 3 ▁to ▁ 7   mm ), ▁though ▁some ▁were ▁larger ▁than ▁ 7   mm . ▁All ▁ 2 7 ▁patients ▁had ▁cor pus ▁call os um ▁les ions . ▁These ▁all ▁had ▁a ▁p unch ed - out ▁appearance ▁on ▁follow ▁up ▁M RI . ▁Though ▁most ▁commonly ▁involving ▁white ▁matter , ▁many ▁patients ▁also ▁had ▁les ions ▁in ▁deep ▁grey ▁matter ▁structures , ▁as ▁well ▁as ▁le pt omen inge al ▁enh ancement . ▁Multiple ▁s cl eros is ▁( MS ) ▁and ▁ac ute ▁dis sem in ated ▁en ce phal omy el itis ▁( A DE M ) ▁can ▁m im ic ▁the ▁M RI ▁changes ▁seen ▁in ▁patients ▁with ▁Sus ac ' s ▁synd rome . ▁However , ▁the ▁call os al ▁les ions ▁in ▁Sus ac ' s ▁synd rome ▁are ▁cent r ally ▁located . ▁In ▁comparison , ▁patients ▁with ▁MS ▁and ▁A DE M ▁typically ▁have ▁les ions ▁involving ▁the ▁unders ur face ▁of ▁the ▁cor pus ▁call os um . ▁Deep ▁gray ▁matter ▁invol vement ▁commonly ▁occurs ▁in ▁A DE M ▁but ▁is ▁very ▁rare ▁in ▁MS . ▁Le pt omen inge al ▁invol vement ▁is ▁not ▁typical ▁of ▁either ▁MS ▁or ▁A DE M . ▁ ▁What ▁this ▁means ▁is ▁that ▁if ▁ 1 0 ▁les ions ▁are ▁found ▁in ▁the ▁brain ▁of ▁an ▁MS ▁patient ,