hanced ▁the ▁CD 8 + ▁T ▁cell ▁imm une ▁response ▁in ▁m ice . ▁IL - 1 5 ▁was ▁needed ▁for ▁CD 4 + ▁T ▁cell ▁heter os ub ty pic ▁protection ▁while ▁using ▁a ▁mult ivalent ▁influen za ▁v acc ine ▁using ▁v acc in ia - based ▁vector . ▁While ▁influen za ▁A ▁virus ▁express ing ▁IL - 1 5 ▁stim ul ates ▁both ▁inn ate ▁and ▁adapt ive ▁imm une ▁cells ▁to ▁decrease ▁tum or ▁growth ▁m ice . ▁ ▁Trans presentation ▁complex es ▁▁ ▁Currently ▁there ▁are ▁two ▁vari eties ▁of ▁IL - 1 5 ▁super agon ist ▁available . ▁One ▁comb ines ▁IL - 1 5 ▁and ▁IL - 1 5 R α - F c ▁( R & D ▁Systems ) ▁in ▁vit ro ▁to ▁generate ▁the ▁complex . ▁It ▁is ▁referred ▁to ▁as ▁IL - 1 5 ▁SA . ▁A ▁second ▁IL - 1 5 ▁super agon ist ▁complex ▁called ▁A LT - 8 0 3 ▁is ▁offered ▁by ▁Al tor ▁Bio S cience . ▁ ▁IL - 1 5 ▁SA ▁ ▁IL - 1 5 ▁SA ▁is ▁currently ▁being ▁evaluated ▁for ▁ant iv iral ▁and ▁ant ican cer ▁activities , ▁in ▁addition ▁to ▁en han cing ▁imm un other apy ▁and ▁v acc ination . ▁One ▁potential ▁short coming ▁of ▁IL - 1 5 ▁SA ▁was ▁its ▁enh ancement ▁of ▁sept ic ▁shock ▁in ▁m ice . ▁ ▁A LT - 8 0 3 ▁ ▁A LT - 8 0 3 ▁is ▁an ▁IL -