▁sp ond yl itis , ▁chron ic ▁low ▁back ▁pain , ▁ac ute ▁pain , ▁and ▁g out . ▁Appro ved ▁indic ations ▁differ ▁by ▁country . ▁ ▁In ▁the ▁U . K ., ▁it ▁is ▁also ▁" used ▁for ▁the ▁short ▁term ▁treatment ▁of ▁moder ate ▁pain ▁after ▁dent al ▁surg ery " ▁of ▁adult s . ▁ ▁A ▁C och rane ▁review ▁ass essed ▁the ▁benefits ▁of ▁single - d ose ▁et or ico x ib ▁in ▁reduction ▁of ▁ac ute ▁post - oper ative ▁pain ▁in ▁adult s . ▁Single - d ose ▁or al ▁et or ico x ib ▁provides ▁four ▁times ▁more ▁pain ▁relief ▁post - oper atively ▁than ▁place bo , ▁with ▁equivalent ▁levels ▁of ▁ad verse ▁events . ▁ ▁E tor ico x ib ▁given ▁at ▁a ▁do se ▁of ▁ 1 2 0   m g ▁is ▁as ▁effective ▁or ▁even ▁better ▁than ▁other ▁anal ges ics ▁that ▁are ▁commonly ▁used . ▁ ▁Ad verse ▁effects ▁ ▁Like ▁all ▁other ▁NS A ID s ▁the ▁CO X - 2 ▁in hib itors ▁too ▁have ▁their ▁share ▁of ▁ad verse ▁effects . ▁F ixed ▁drug ▁er u ption ▁and ▁general ised ▁er yth ema , ▁ac ute ▁generalized ▁ex anth emat ous ▁p ust ul osis ▁( AGE P ), ▁er yth ema ▁mult iform e ▁like ▁er u ption ▁and ▁drug ▁induced ▁pret ib ial ▁er yth ema ▁are ▁some ▁serious ▁side ▁effects ▁reported , ▁besides ▁the ▁usual ▁innoc uous ▁ones . ▁ ▁Mechan ism