▁University ▁Hospital ▁where ▁she ▁had ▁roman ces ▁with ▁both ▁Bill ▁H orton ▁( Christ opher ▁Stone ) ▁and ▁Mike ▁H orton ▁( Michael ▁T . ▁We iss ). ▁Her ▁rom ance ▁with ▁Bill ▁t ore ▁the ▁H orton ▁family ▁apart ▁and ▁made ▁plans ▁to ▁leave ▁S alem ▁in ▁March ▁ 1 9 8 8 ▁when ▁she ▁was ▁murder ed ▁by ▁the ▁River front ▁Kn ifer , ▁making ▁her ▁his ▁second ▁murder ▁victim . ▁ ▁Sam anth a ▁Evans ▁ ▁Sam anth a ▁Evans ▁was ▁port rayed ▁by ▁Andrea ▁Hall , ▁the ▁tw in ▁sister ▁of ▁fellow ▁Days ▁of ▁Our ▁L ives ▁actress , ▁De id re ▁Hall , ▁who ▁port ray s ▁Sam anth a ' s ▁tw in ▁sister , ▁Mar l ena . ▁Mar l ena ▁named ▁her ▁first ▁daughter , ▁Sam anth a , ▁after ▁her ▁sister . ▁Sam anth a ▁appeared ▁from ▁ 1 9 7 7 ▁to ▁ 1 9 8 0 , ▁with ▁a ▁brief ▁repr is al ▁in ▁ 1 9 8 2 , ▁when ▁the ▁character ▁was ▁killed ▁by ▁the ▁S alem ▁Str ang ler . ▁De id re ▁briefly ▁port rayed ▁Sam anth a ▁in ▁newly ▁created ▁flash back s ▁ 1 9 9 2 ▁and ▁ 2 0 0 8 , ▁respectively . ▁ ▁Kate ▁Win og rad ▁ ▁Dr ▁Kate ▁Win og rad , ▁played ▁by ▁Ela ine ▁Princi , ▁first ▁appears ▁in ▁July ▁ 1 9 7 7 , ▁when ▁she ▁is ▁Head ▁of ▁An est h esi ology ▁at ▁S