▁Se ñ ora ▁de ▁la ▁Ant igua ") ▁is ▁followed ▁by ▁the ▁" First ▁ser mon ▁to ▁Saint ▁Anthony ▁the ▁Abb ot " ▁(" S erm ón ▁Prim ero ▁de ▁San ▁Antonio ▁Ab ad "), ▁pre ached ▁in ▁ 1 6 5 8 ; ▁the ▁" First ▁S erm on ▁to ▁Saint ▁Bla ise , ▁bishop ▁and ▁mart yr " ▁(" S erm ón ▁de ▁San ▁Bl as ▁ob is po ▁y ▁má rt ir "), ▁pre ached ▁in ▁ 1 6 5 9 ; ▁and ▁" The ▁pan egy ric ▁prayer ▁to ▁James ▁the ▁Great ▁( or ▁Mo ors layer )" ▁(" O ra ción ▁pan eg ír ica ▁al ▁gl or ioso ▁Ap ó st ol ▁Santiago ") ▁in ▁ 1 6 6 0 , ▁perhaps ▁the ▁most ▁important ▁ser mon ▁for ▁the ▁compreh ension ▁of ▁Juan ▁de ▁Esp in osa ▁Med rano ' s ▁o e uv re . ▁In ▁ 1 6 6 2 , ▁in ▁Lima , ▁the ▁Ap olog etic ▁in ▁defense ▁of ▁Luis ▁de ▁Gó ng ora ▁( Ap olog ético ▁en ▁favor ▁de ▁Don ▁Luis ▁de ▁Gó ng ora ) ▁is ▁published . ▁It ▁is ▁important ▁to ▁highlight , ▁however , ▁that ▁Esp in osa ▁Med rano ' s ▁intellectual ▁activity ▁in ▁the ▁prof ane ▁had ▁already ▁started ▁in ▁the ▁de cade ▁of ▁ 1 6 5 0 ▁— the ▁bib lic al ▁play ▁To ▁Love ▁One ' s ▁O wn ▁Death ▁( A mar ▁su ▁prop ia ▁muerte ) ▁had ▁been ▁written ▁c .