▁century , ▁and ▁pl ague ▁ep ide m ics ▁affected ▁Hon ol ulu ▁and ▁San ▁Francisco ▁from ▁ 1 8 9 9 ▁until ▁ 1 9 0 1 . ▁State ▁govern ments ▁generally ▁re lied ▁on ▁the ▁cord on ▁san itaire ▁as ▁a ▁ge ographic ▁quar antine ▁measure ▁to ▁control ▁the ▁movement ▁of ▁people ▁into ▁and ▁out ▁of ▁affected ▁communities . ▁During ▁the ▁▁ 1 9 1 8 ▁influen za ▁pan demic , ▁some ▁communities ▁instit uted ▁protect ive ▁se quest r ation ▁( s ometimes ▁referred ▁to ▁as ▁" reverse ▁quar antine ") ▁to ▁keep ▁the ▁inf ected ▁from ▁introdu cing ▁influen za ▁into ▁health y ▁populations . ▁ ▁By ▁the ▁middle ▁of ▁the ▁ 1 9 th ▁century , ▁the ▁Ott oman ▁Empire ▁had ▁established ▁quar antine ▁stations , ▁including ▁in ▁An atol ia ▁and ▁the ▁B alk ans . ▁For ▁example , ▁at ▁the ▁port ▁of ▁Iz mir , ▁all ▁ships ▁and ▁their ▁cargo ▁would ▁be ▁ins pected ▁and ▁those ▁sus pected ▁of ▁carrying ▁the ▁pl ague ▁would ▁be ▁to wed ▁to ▁separate ▁do cks ▁and ▁their ▁personnel ▁hous ed ▁in ▁separate ▁buildings ▁for ▁a ▁determined ▁period ▁of ▁time . ▁In ▁Th ess aly , ▁along ▁the ▁Greek - T urk ish ▁border , ▁all ▁trav ellers ▁entering ▁and ▁exit ing ▁the ▁Ott oman ▁Empire ▁would ▁be ▁quar ant ined ▁for ▁ 9 – 1 5 ▁days . ▁Upon ▁appearance ▁of ▁the ▁pl ague , ▁the ▁quar antine ▁stations ▁would ▁be ▁militar ised ▁and ▁the ▁Ott oman ▁army ▁would ▁be