ia ▁able ▁to ▁bre ach ▁the ▁shall ow ▁pun ct ure ▁site ▁of ▁mic r one ed les . ▁ ▁Dis adv antages ▁ ▁There ▁are ▁some ▁concerns ▁about ▁how ▁phys icians ▁can ▁be ▁sure ▁that ▁all ▁of ▁the ▁drug ▁or ▁v acc ine ▁has ▁entered ▁the ▁skin ▁when ▁mic r one ed les ▁are ▁applied . ▁H ollow ▁and ▁co ated ▁mic r one ed les ▁both ▁possess ▁the ▁risk ▁that ▁the ▁drug ▁will ▁not ▁properly ▁enter ▁the ▁skin ▁and ▁will ▁not ▁be ▁effective . ▁Both ▁of ▁these ▁types ▁of ▁mic r one ed les ▁can ▁leak ▁onto ▁a ▁person ' s ▁skin ▁either ▁by ▁damage ▁of ▁the ▁mic r one ed le ▁or ▁incorrect ▁application ▁by ▁the ▁phys ician . ▁This ▁is ▁why ▁it ▁is ▁essential ▁that ▁phys icians ▁are ▁trained ▁how ▁to ▁properly ▁apply ▁the ▁arrays . ▁▁▁ ▁Another ▁concern ▁is ▁that ▁incorrectly ▁applied ▁arrays ▁could ▁leave ▁foreign ▁material ▁in ▁the ▁body . ▁Although ▁there ▁is ▁a ▁lower ▁risk ▁of ▁in fection ▁associated ▁with ▁mic r one ed les , ▁the ▁arrays ▁are ▁more ▁frag ile ▁than ▁a ▁typical ▁hyp od erm ic ▁need le ▁due ▁to ▁their ▁small ▁size ▁and ▁thus ▁have ▁a ▁chance ▁of ▁breaking ▁off ▁and ▁remaining ▁in ▁the ▁skin . ▁Some ▁of ▁the ▁material ▁used ▁to ▁construct ▁the ▁mic r one ed les , ▁such ▁as ▁tit an ium , ▁cannot ▁be ▁absor bed ▁by ▁the ▁body ▁and ▁any ▁fragments ▁of ▁the ▁need les ▁would ▁cause ▁ir rit ation . ▁▁▁ ▁There ▁is ▁a ▁limited ▁amount