. ▁The ▁use ▁of ▁R IC ▁or ▁N ST ▁made ▁it ▁possible ▁to ▁apply ▁much ▁sa fer ▁cur ative ▁stem ▁cell ▁trans plant ation ▁for ▁every ▁patient ▁in ▁need ▁with ▁no ▁lower ▁or ▁upper ▁age ▁restriction , ▁including ▁also ▁patients ▁with ▁less ▁than ▁optimal ▁clin ical ▁condition ▁that ▁would ▁not ▁be ▁el ig ible ▁for ▁the ▁standard ▁my elo abl ative ▁stem ▁cell ▁trans plant ation . ▁ ▁B ax ter ▁International ▁recognized ▁the ▁potential ▁of ▁cell ▁ther apy ▁and ▁signed ▁an ▁agreement ▁which ▁resulted ▁in ▁major ▁invest ment ▁with ▁S la vin ▁at ▁Had ass ah ▁Medical ▁Center ▁for ▁further ▁development ▁of ▁new ▁approaches ▁based ▁on ▁cell ▁ther apy ▁for ▁the ▁treatment ▁of ▁cancer , ▁auto imm une ▁dise ases ▁and ▁organ ▁trans plant ation ▁based ▁on ▁new ▁approaches ▁for ▁reg ulation ▁rather ▁than ▁non - specific ▁supp ression ▁of ▁the ▁imm une ▁system . ▁According ly , ▁S la vin ' s ▁research ▁center ▁was ▁established ▁by ▁B ax ter ▁International ▁based ▁in ▁Chicago , ▁USA ▁and ▁also ▁supported ▁by ▁the ▁D anny ▁C unn iff ▁Le uk emia ▁Research ▁Center . ▁S la vin ▁was ▁founder ▁and ▁director ▁of ▁this ▁research ▁center ▁in ▁ 1 9 9 4 – 2 0 0 7 . ▁ ▁S la vin ▁with ▁his ▁team ▁using ▁a ▁vector ▁provided ▁by ▁the ▁San ▁R aff ae le ▁Hospital ▁in ▁Milan ▁pione ered ▁the ▁first ▁successful ▁use ▁of ▁gene ▁ther apy ▁for ▁treatment ▁of ▁b ubble ▁baby ▁born ▁with ▁ad en os ine ▁de amin ase