▁Data ▁Bank ▁of ▁Japan , ▁European ▁N uc le ot ide ▁Archive , ▁and ▁Gen B ank ▁under ▁the ▁acc ession ▁numbers ▁L N 8 3 1 0 3 4 ▁and ▁CP 0 2 8 8 4 1 . ▁ ▁Bio film ▁formation ▁ ▁Bio fil ms ▁are ▁a ▁way ▁for ▁S . ▁py ogen es , ▁as ▁well ▁as ▁other ▁b acter ial ▁cells , ▁to ▁communicate ▁with ▁each ▁other . ▁In ▁the ▁bio film ▁gene ▁expression ▁for ▁multiple ▁purposes ▁( such ▁as ▁def ending ▁against ▁the ▁host ▁imm une ▁system ) ▁is ▁controlled ▁via ▁qu orum ▁sens ing . ▁One ▁of ▁the ▁bio film ▁forming ▁path ways ▁in ▁G AS ▁is ▁the ▁R gg 2 / 3 ▁path way . ▁It ▁regul ates ▁S HP ' s ▁( short ▁hydro ph ob ic ▁pe pt ides ) ▁that ▁are ▁qu orum ▁sens ing ▁ph er om ones ▁a . k . a . ▁auto ind uc ers . ▁The ▁S HP ' s ▁are ▁translated ▁to ▁an ▁imm ature ▁form ▁of ▁the ▁ph er om one ▁and ▁must ▁under go ▁processing , ▁first ▁by ▁a ▁metal lo prote ase ▁en zym e ▁inside ▁the ▁cell ▁and ▁then ▁in ▁the ▁ext rac ell ular ▁space , ▁to ▁reach ▁their ▁m ature ▁active ▁form . ▁The ▁mode ▁of ▁transport ation ▁out ▁of ▁the ▁cell ▁and ▁the ▁ext rac ell ular ▁processing ▁factor ( s ) ▁are ▁still ▁unknown . ▁The ▁m ature ▁S HP ▁ph er om one ▁can ▁then ▁be ▁taken ▁in