ics ▁are ▁the ▁third ▁largest ▁minor ity ▁group ▁in ▁San ▁Francisco ▁County . ▁ ▁The ▁largest ▁ancest ry ▁group ▁of ▁His pan ics ▁in ▁San ▁Francisco ▁County ▁are ▁of ▁Mexican ▁descent ▁( 5 2 . 7 % ▁of ▁His pan ics ) ▁followed ▁by ▁Salvador an ▁descent ▁( 1 2 . 0 % ▁of ▁His pan ics ), ▁Nic ar agu an ▁descent ▁( 8 . 0 % ), ▁Gu atem al an ▁descent ▁( 5 . 3 % ), ▁Puerto ▁R ican ▁descent ▁( 3 . 7 % ), ▁Sp ani ard ▁descent ▁( 2 . 9 % ), ▁Per uv ian ▁descent ▁( 2 . 8 % ), ▁Chile an ▁descent ▁( 1 . 4 % ), ▁Colomb ian ▁descent ▁( 1 . 4 % ), ▁Cub an ▁descent ▁( 1 . 3 % ), ▁Argent in ian ▁descent ▁( 1 . 1 % ), ▁and ▁those ▁of ▁other ▁His pan ic ▁eth nic ity ▁or ▁of ▁mixed ▁His pan ic ▁eth nic ity ▁( 7 . 4 %). ▁ ▁White ▁Americans ▁ ▁As ▁of ▁July ▁ 2 0 1 8 , ▁White ▁Americans ▁in ▁San ▁Francisco ▁are ▁ 4 5 . 4 % ▁of ▁the ▁population ▁of ▁San ▁Francisco . ▁Non - H is pan ic ▁whites ▁are ▁ 4 0 . 0 % ▁of ▁the ▁population . ▁ ▁History ▁White ▁people ▁of ▁European ▁descent , ▁first ▁the ▁Spanish , ▁gradually ▁disp la ced ▁the ▁native ▁people ▁of ▁the ▁area ▁that ▁would ▁eventually ▁become ▁San ▁Francisco . ▁ ▁Ne igh