, ▁with ▁an ▁unusual ▁mechanism ▁of ▁action ▁involving ▁the ▁se quest r ation ▁of ▁iron ▁inside ▁the ▁b acter ial ▁cells , ▁that ▁thereby ▁inter fer es ▁with ▁their ▁ability ▁to ▁reg ulate ▁the ▁p H ▁balance ▁across ▁the ▁cell ▁memb rane ▁properly . ▁Since ▁this ▁is ▁a ▁different ▁mode ▁of ▁action ▁from ▁most ▁ant ib iot ics , ▁hal ic in ▁retained ▁activity ▁against ▁b acter ial ▁stra ins ▁resist ant ▁to ▁many ▁commonly ▁used ▁dru gs . ▁ ▁Pre lim inary ▁studies ▁suggest ▁that ▁hal ic in ▁k ills ▁b acter ia ▁by ▁dis rupt ing ▁their ▁ability ▁to ▁maintain ▁an ▁electro chem ical ▁gradient ▁across ▁their ▁cell ▁memb ran es . ▁This ▁gradient ▁is ▁necessary , ▁among ▁other ▁functions , ▁to ▁produce ▁ATP ▁( m ole cules ▁that ▁cells ▁use ▁to ▁store ▁energy ), ▁so ▁if ▁the ▁gradient ▁breaks ▁down , ▁the ▁cells ▁die . ▁This ▁type ▁of ▁killing ▁mechanism ▁could ▁be ▁difficult ▁for ▁b acter ia ▁to ▁develop ▁resistance ▁to . ▁ ▁References ▁▁ ▁Category : En zym e ▁in hib itors ▁Category : Ant ib iot ics <0x0A> </s> ▁Mary ▁Ron an ▁was ▁the ▁Super int endent ▁for ▁C inc inn ati ▁Public ▁School s , ▁un anim ously ▁voted ▁by ▁the ▁C inc inn ati ▁Board ▁of ▁Education ▁on ▁April ▁ 1 6 , ▁ 2 0 0 9 . ▁She ▁served ▁as ▁an ▁Inter im ▁Super int endent ▁on ▁August ▁ 1 , ▁ 2 0 0 8 , ▁succeed ing ▁ret ire e ▁Rosa ▁Black