z aret ▁( on ▁a ▁small ▁island ▁ad jo ining ▁the ▁city ) ▁in ▁ 1 4 0 3 . ▁In ▁ 1 4 6 7 ▁Gen oa ▁followed ▁the ▁example ▁of ▁Ven ice , ▁and ▁in ▁ 1 4 7 6 ▁the ▁old ▁le per ▁hospital ▁of ▁Marse ille ▁was ▁converted ▁into ▁a ▁pl ague ▁hospital . ▁The ▁great ▁la z aret ▁of ▁Marse ille , ▁perhaps ▁the ▁most ▁complete ▁of ▁its ▁kind , ▁was ▁founded ▁in ▁ 1 5 2 6 ▁on ▁the ▁island ▁of ▁Pom èg ues . ▁The ▁practice ▁at ▁all ▁the ▁Mediter rane an ▁la z are ts ▁did ▁not ▁differ ▁from ▁the ▁English ▁procedure ▁in ▁the ▁Lev antine ▁and ▁North ▁African ▁trade . ▁On ▁the ▁arrival ▁of ▁ch ol era ▁in ▁ 1 8 3 1 ▁some ▁new ▁la z are ts ▁were ▁set ▁up ▁at ▁western ▁ports , ▁not ably ▁a ▁very ▁extensive ▁establishment ▁near ▁Bor de aux , ▁afterwards ▁turned ▁to ▁another ▁use . ▁ ▁Modern ▁history ▁ ▁Ep ide m ics ▁of ▁yellow ▁fe ver ▁rav aged ▁urban ▁communities ▁in ▁North ▁America ▁throughout ▁the ▁late - e igh teenth ▁and ▁early - n in ete enth ▁centuries , ▁the ▁best - known ▁examples ▁being ▁the ▁ 1 7 9 3 ▁Philadelphia ▁yellow ▁fe ver ▁ep ide mic ▁and ▁out break s ▁in ▁Georgia ▁( 1 8 5 6 ) ▁and ▁Florida ▁( 1 8 8 8 ). ▁Ch ol era ▁and ▁small po x ▁ep ide m ics ▁continued ▁throughout ▁the ▁nin ete enth