1 5 ▁and ▁its ▁re ceptor ▁sub unit ▁alpha ▁( IL - 1 5 R α ) ▁are ▁also ▁produced ▁by ▁ske let al ▁mus cle ▁in ▁response ▁to ▁different ▁exercise ▁dos es ▁( my ok ine ), ▁playing ▁significant ▁roles ▁in ▁vis cer al ▁( int ra - ab dom inal ▁or ▁inter st it ial ) ▁fat ▁reduction ▁ ▁and ▁my of ibr ill ar ▁protein ▁synth esis ▁( hy pert ro phy ). ▁ ▁D ise ase ▁ ▁Ep stein - B arr ▁virus ▁▁ ▁In ▁humans ▁with ▁history ▁of ▁ac ute ▁inf ect ious ▁mon on uc le osis ▁( the ▁synd rome ▁associated ▁with ▁primary ▁Ep stein - B arr ▁virus ▁in fection ), ▁IL - 1 5 R ▁express ing ▁l ym ph ocy tes ▁are ▁not ▁detected ▁even ▁ 1 4 ▁years ▁after ▁in fection . ▁ ▁Cel iac ▁disease ▁▁ ▁There ▁have ▁been ▁recent ▁studies ▁suggesting ▁that ▁supp ression ▁of ▁IL - 1 5 ▁may ▁be ▁a ▁potential ▁treatment ▁for ▁cel iac ▁disease ▁and ▁even ▁presents ▁the ▁possibility ▁of ▁prevent ing ▁its ▁development . ▁In ▁one ▁study ▁with ▁m ice ▁blocking ▁IL - 1 5 ▁with ▁an ▁ant ib ody ▁led ▁to ▁the ▁revers al ▁of ▁auto imm une ▁int est inal ▁damage . ▁In ▁another ▁study ▁m ice ▁used ▁were ▁able ▁to ▁eat ▁gl uten ▁without ▁developing ▁sympt oms . ▁ ▁Non - al co hol ic ▁fat ty ▁li ver ▁disease ▁ ▁A ▁recent ▁report ▁indicated ▁IL - 1 5 ▁prom otes ▁non