hes ion ▁between ▁cells . ▁It ▁may ▁also ▁be ▁responsible ▁for ▁transm itting ▁the ▁contact ▁in hib ition ▁signal ▁that ▁causes ▁cells ▁to ▁stop ▁div iding ▁once ▁the ▁ep ith el ial ▁sheet ▁is ▁complete . ▁The ▁E - c ad her in ▁– ▁ β - c aten in ▁– ▁α - c aten in ▁complex ▁is ▁weak ly ▁associated ▁to ▁act in ▁fil aments . ▁Ad her ens ▁j unction s ▁require ▁significant ▁protein ▁dynamics ▁in ▁order ▁to ▁link ▁to ▁the ▁act in ▁c yt os ke leton , ▁thereby ▁en abling ▁mechan otr ans du ction . ▁ ▁An ▁important ▁component ▁of ▁the ▁ad her ens ▁j unction s ▁are ▁the ▁cad her in ▁prote ins . ▁Cad her ins ▁form ▁the ▁cell - cell ▁j unction al ▁structures ▁known ▁as ▁ad her ens ▁j unction s ▁as ▁well ▁as ▁the ▁des mos om es . ▁Cad her ins ▁are ▁capable ▁of ▁hom oph il ic ▁interactions ▁through ▁their ▁ext rac ell ular ▁cad her in ▁repeat ▁domains , ▁in ▁a ▁Ca 2 + - dependent ▁manner ; ▁this ▁can ▁hold ▁adjacent ▁ep ith el ial ▁cells ▁together . ▁While ▁in ▁the ▁ad her ens ▁j unction , ▁cad her ins ▁rec ruit ▁ β - c aten in ▁mole cules ▁onto ▁their ▁int rac ell ular ▁regions . ▁ β - c aten in , ▁in ▁turn , ▁associ ates ▁with ▁another ▁highly ▁dynamic ▁protein , ▁α - c aten in , ▁which ▁directly ▁bind s ▁to ▁the ▁act