or on ▁comp ounds ▁are ▁relatively ▁non to xic ▁to ▁humans ▁and ▁animals ▁( with ▁to x icity ▁similar ▁to ▁that ▁of ▁table ▁salt ). ▁The ▁L D 5 0 ▁( d ose ▁at ▁which ▁there ▁is ▁ 5 0 % ▁mort ality ) ▁for ▁animals ▁is ▁about ▁ 6   g ▁per ▁kg ▁of ▁body ▁weight . ▁Sub st ances ▁with ▁L D 5 0 ▁above ▁ 2   g ▁are ▁considered ▁non to xic . ▁An ▁int ake ▁of ▁ 4   g / day ▁of ▁bor ic ▁acid ▁was ▁reported ▁without ▁incident , ▁but ▁more ▁than ▁this ▁is ▁considered ▁to xic ▁in ▁more ▁than ▁a ▁few ▁dos es . ▁Int akes ▁of ▁more ▁than ▁ 0 . 5   gram s ▁per ▁day ▁for ▁ 5 0 ▁days ▁cause ▁minor ▁dig est ive ▁and ▁other ▁problems ▁suggest ive ▁of ▁to x icity . ▁Diet ary ▁supp lement ation ▁of ▁bor on ▁may ▁be ▁helpful ▁for ▁b one ▁growth , ▁w ound ▁he aling , ▁and ▁ant io x id ant ▁activity , ▁and ▁ins u fficient ▁amount ▁of ▁bor on ▁in ▁di et ▁may ▁result ▁in ▁bor on ▁def ic iency . ▁ ▁Single ▁medical ▁dos es ▁of ▁ 2 0   g ▁of ▁bor ic ▁acid ▁for ▁neut ron ▁capture ▁ther apy ▁have ▁been ▁used ▁without ▁und ue ▁to x icity . ▁ ▁Bor ic ▁acid ▁is ▁more ▁to xic ▁to ▁insect s ▁than ▁to ▁m amm als , ▁and ▁is ▁rout in ely ▁used ▁as ▁an ▁insect ic