▁can ▁be ▁trained ▁to ▁do ▁this ▁them self . ▁Cont in ued ▁use ▁of ▁the ▁drug ▁should ▁take ▁place ▁until ▁the ▁administration ▁of ▁h CG ▁begins . ▁h CG ▁administration ▁is ▁begun ▁when ▁a ▁sufficient ▁number ▁of ▁fol lic les ▁have ▁developed ▁due ▁to ▁the ▁effects ▁of ▁end ogen ous ▁and ▁or ▁ex ogen ously ▁admin ister ed ▁fol lic le ▁stim ulating ▁h orm one . ▁ ▁Cont ra ind ic ations ▁Gan ire li x ▁should ▁not ▁be ▁used ▁in ▁women ▁who ▁are ▁already ▁pre gn ant , ▁and ▁because ▁of ▁this ▁the ▁on set ▁of ▁pre gn ancy ▁must ▁be ▁ruled ▁out ▁before ▁it ▁is ▁admin ister ed . ▁Women ▁using ▁gan ire li x ▁should ▁not ▁breast ▁feed , ▁as ▁it ▁is ▁not ▁known ▁whether ▁gan ire li x ▁is ▁ex cret ed ▁in ▁breast ▁milk . ▁ ▁Side ▁effects ▁C lin ical ▁studies ▁have ▁shown ▁that ▁the ▁most ▁common ▁side ▁effect ▁is ▁a ▁slight ▁reaction ▁at ▁the ▁site ▁of ▁injection ▁in ▁the ▁form ▁of ▁red ness , ▁and ▁sometimes ▁sw elling . ▁C lin ical ▁studies ▁have ▁shown ▁that , ▁one ▁hour ▁after ▁injection , ▁the ▁inc idence ▁of ▁at ▁least ▁one ▁moder ate ▁or ▁severe ▁local ▁skin ▁reaction ▁per ▁treatment ▁cycle ▁was ▁ 1 2 % ▁in ▁ 4 ▁patients ▁treated ▁with ▁gan ire li x ▁and ▁ 2 5 % ▁in ▁patients ▁treated ▁sub cut ane ously ▁with ▁a ▁G n R H ▁ag on ist . ▁The ▁local ▁re actions ▁generally ▁disappear ▁within ▁ 4