▁S od om ▁and ▁G om or rah ▁P ill ar ▁of ▁Salt , ▁a ▁road ▁sign ▁in ▁B ury ▁St ▁Edmund s ▁in ▁Su ff olk , ▁England , ▁thought ▁to ▁be ▁the ▁first ▁internally ▁ill umin ated ▁road ▁sign ▁in ▁the ▁country ▁" P ill ar ▁of ▁Salt " ▁( F ear ▁the ▁Walk ing ▁Dead ), ▁a ▁television ▁episode ▁The ▁P ill ar ▁of ▁Salt ▁( La ▁statue ▁de ▁sel ), ▁a ▁ 1 9 5 3 ▁novel ▁by ▁Albert ▁Mem mi <0x0A> </s> ▁D if l up red n ate ▁is ▁a ▁cort ic ost ero id , ▁It ▁is ▁chem ically ▁a ▁but yr ate ▁est er ▁of ▁ 6 ( alpha ), 9 ( alpha )- d if lu oro ▁pred nis ol one ▁ac et ate . ▁According ly , ▁dif l up red n ate ▁is ▁sometimes ▁abbre vi ated ▁D F BA , ▁for ▁dif lu or op red nis ol one ▁but yr ate ▁ac et ate . ▁ ▁Appro val ▁On ▁June ▁ 2 4 , ▁ 2 0 0 8 , ▁the ▁US ▁Food ▁and ▁D rug ▁Administration ▁( F DA ) ▁approved ▁dif l up red n ate ▁for ▁the ▁treatment ▁of ▁post - oper ative ▁oc ular ▁infl amm ation ▁and ▁pain . ▁It ▁is ▁market ed ▁by ▁Al con ▁under ▁the ▁trad ename ▁D ure z ol . ▁ ▁C lin ical ▁tri als ▁D if l up red n ate ▁o ph th al mic ▁em ulsion