▁to ▁stim ulate ▁protein ▁synth esis . ▁It ▁is ▁reported ▁to ▁have ▁multiple ▁targets , ▁including ▁stim ulating ▁m T OR ▁and ▁decre asing ▁prote as ome ▁expression . ▁Its ▁use ▁to ▁prevent ▁the ▁loss ▁of ▁lean ▁body ▁mass ▁in ▁older ▁adult s ▁is ▁consist ently ▁supported ▁in ▁clin ical ▁tri als . ▁More ▁research ▁is ▁needed ▁to ▁determine ▁the ▁precise ▁effects ▁of ▁H MB ▁on ▁mus cle ▁strength ▁and ▁function ▁in ▁this ▁age ▁group . ▁ ▁Ep ide mi ology ▁ ▁The ▁pre val ence ▁of ▁s arc open ia ▁depends ▁on ▁the ▁definition ▁used ▁in ▁each ▁ep ide mi ological ▁study . ▁Est im ated ▁pre val ence ▁in ▁ 6 0 - 7 0 ▁year ▁old ▁people ▁is ▁ 5 - 1 3 % ▁and ▁increases ▁to ▁ 1 1 - 5 0 % ▁in ▁people ▁over ▁ 8 0 ▁years ▁of ▁age . ▁This ▁equ ates ▁to ▁> 5 0 ▁million ▁people ▁and ▁is ▁project ed ▁to ▁affect ▁> 2 0 0 ▁million ▁in ▁the ▁next ▁ 4 0 ▁years ▁given ▁the ▁rising ▁population ▁of ▁older ▁adult s . ▁ ▁Public ▁health ▁impact ▁S arc open ia ▁is ▁emer ging ▁as ▁a ▁major ▁public ▁health ▁concern ▁given ▁the ▁increased ▁lon ge vity ▁of ▁industrial ized ▁populations ▁and ▁growing ▁ger iat ric ▁population . ▁S arc open ia ▁is ▁a ▁predict or ▁of ▁many ▁ad verse ▁out comes ▁including ▁increased ▁dis ability , ▁falls ▁and ▁mort ality . ▁Im m ob ility ▁or ▁bed ▁rest ▁in ▁populations ▁pre dis posed