ros is ▁and ▁ne cro infl am mat ory ▁activity ▁in ▁the ▁li ver . ▁ ▁F ib ro Test ▁has ▁been ▁evaluated ▁in ▁relation ▁to ▁li ver ▁bi ops y ▁( the ▁current ▁reference ▁standard ▁in ▁li ver ▁disease ▁assess ment ) ▁in ▁people ▁with ▁he pat itis ▁C , ▁he pat itis ▁B , ▁alco hol ic ▁li ver ▁disease , ▁and ▁non - al co hol ic ▁fat ty ▁li ver ▁disease . ▁They ▁are ▁most ▁useful ▁for ▁cir r hos is ▁and ▁less ▁useful ▁for ▁other ▁stages ▁of ▁li ver ▁disease . ▁ ▁By ▁ 2 0 0 8 ▁it ▁had ▁been ▁used ▁in ▁over ▁ 3 5 0 , 0 0 0 ▁patients . ▁In ▁ 2 0 0 6 , ▁the ▁French ▁National ▁Author ity ▁for ▁Health ▁recommended ▁the ▁use ▁of ▁F ib ro Test ▁as ▁one ▁of ▁a ▁number ▁of ▁first - line ▁assess ment ▁tool ▁for ▁fib ros is ▁with ▁un tre ated ▁chron ic ▁he pat itis ▁C . ▁ ▁Pro cedure ▁The ▁F ib ro Test ▁score ▁is ▁calculated ▁from ▁the ▁results ▁of ▁a ▁six - parameter ▁blood ▁test , ▁combining ▁six ▁ser um ▁markers ▁with ▁the ▁age ▁and ▁gender ▁of ▁the ▁patient : ▁Al pha - 2 - mac rog lob ul in , ▁H apt og lo bin , ▁Apol ip op rote in ▁A 1 , ▁G amma - gl ut am yl ▁trans pe pt id ase ▁( G GT ), ▁Total ▁bil ir ub in , ▁and ▁Alan