▁the ▁supporting ▁evidence . ▁ ▁Software ▁and ▁data ▁access ▁ ▁The ▁project ▁is ▁open ▁source ▁- ▁all ▁data ▁and ▁all ▁software ▁that ▁is ▁produced ▁in ▁the ▁project ▁can ▁be ▁freely ▁accessed ▁and ▁used . ▁ ▁Database ▁contents ▁As ▁of ▁December ▁ 2 0 , ▁ 2 0 0 6 , ▁O Reg An no ▁contained ▁ 4 2 2 0 ▁regul atory ▁sequences ▁( ex cluding ▁deprecated ▁records ) ▁for ▁ 2 1 9 0 ▁trans cription ▁factor ▁binding ▁sites , ▁ 1 8 5 3 ▁regul atory ▁regions ▁( en h anc ers , ▁prom ot ers , ▁etc .), ▁ 1 7 0 ▁regul atory ▁polym orph isms , ▁and ▁ 7 ▁regul atory ▁ha plot ypes ▁for ▁ 1 7 ▁different ▁organ isms ▁( pred omin antly ▁D ros oph ila ▁mel an og aster , ▁H omo ▁s api ens , ▁Mus ▁mus cul us , ▁Ca en or hab d itis ▁eleg ans , ▁and ▁R att us ▁nor veg icus ▁in ▁that ▁order ). ▁ ▁These ▁records ▁were ▁obtained ▁by ▁manual ▁c uration ▁of ▁ 8 2 8 ▁publications ▁by ▁ 4 5 ▁O Reg An no ▁users ▁from ▁the ▁gene ▁reg ulation ▁community . ▁ ▁The ▁O Reg An no ▁publication ▁queue ▁contained ▁ 4 2 1 5 ▁publications ▁of ▁which ▁ 8 5 8 ▁were ▁closed , ▁ 3 4 ▁were ▁in ▁progress ▁( open ▁status ), ▁and ▁ 3 3 2 1 ▁were ▁await ing ▁annotation ▁( p ending ▁status ). ▁O Reg An