associ ated ▁protein ▁SN AP 2 5 ▁are ▁the ▁main ▁components ▁of ▁a ▁protein ▁complex ▁involved ▁in ▁the ▁dock ing ▁and / or ▁fusion ▁of ▁syn apt ic ▁ves icles ▁with ▁the ▁pres yn apt ic ▁memb rane . ▁V AMP 1 ▁is ▁a ▁member ▁of ▁the ▁ves icle - associ ated ▁memb rane ▁protein ▁( V AMP )/ syn apt obre vin ▁family . ▁Multiple ▁alternative ▁sp lice ▁variants ▁that ▁encode ▁prote ins ▁with ▁alternative ▁car box y ▁ends ▁have ▁been ▁described , ▁but ▁the ▁full - length ▁nature ▁of ▁some ▁variants ▁has ▁not ▁been ▁defined . ▁ ▁C lin ical ▁significance ▁▁ ▁H omo zy g ous ▁mut ations ▁in ▁V AMP 1 ▁have ▁been ▁identified ▁in ▁a ▁series ▁of ▁children ▁affected ▁with ▁a ▁form ▁of ▁con gen ital ▁my as then ic ▁synd rome ▁and ▁similar ▁pres yn apt ic ▁features ▁in ▁these ▁patients ▁ ▁and ▁the ▁knock - out ▁V AMP 1 ▁mouse ▁have ▁been ▁demonstrated . ▁ ▁Inter active ▁path way ▁map ▁ ▁References ▁ ▁Further ▁reading <0x0A> </s> ▁Albert ▁Pr att ▁( 1 6 ▁April ▁ 1 8 9 3 ▁– ▁ 1 9 ▁July ▁ 1 9 1 6 ) ▁was ▁a ▁New ▁Zealand ▁cr ick eter . ▁He ▁played ▁one ▁first - class ▁match ▁for ▁A uck land ▁in ▁ 1 9 1 2 / 1 3 . ▁He ▁was ▁killed ▁in ▁action ▁during ▁World ▁War ▁I . ▁ ▁See ▁also ▁ ▁List ▁of ▁A uck land ▁representative ▁cr ick eters ▁ ▁List ▁of ▁cr