. ▁ ▁Dam age ▁Associ ated ▁M ole cular ▁Pattern ▁model ▁research ▁ ▁The ▁major ▁focus ▁of ▁Se ong ' s ▁lab ▁is ▁to ▁obtain ▁a ▁more ▁thorough ▁understanding ▁of ▁the ▁D AMP s ▁model ▁of ▁imm unity ▁and ▁the ▁potential ▁impact ▁this ▁model ▁may ▁have ▁in ▁the ▁treatment ▁of ▁infl am mat ory ▁dise ases . ▁The ▁D AMP s ▁model ▁was ▁suggested ▁by ▁Se ong ▁in ▁ 2 0 0 4 ▁and ▁comb ines ▁elements ▁of ▁the ▁Self - Non - Self ▁and ▁D anger ▁Model ▁to ▁explain ▁inn ate ▁imm une ▁response . ▁The ▁D AMP s ▁model ▁involves ▁the ▁imm une - st im ul atory ▁ability ▁of ▁exposed ▁hydro ph ob ic ▁port ions ▁of ▁den ature d ▁mole cules ▁( hy pp os , ▁water - ins ol ub le ▁mole cules ) ▁from ▁both ▁end ogen ous ▁and ▁ex ogen ous ▁sources . ▁Se ong ▁propos es ▁that ▁PA MP s , ▁and ▁al ar min ▁origin ated ▁from ▁a ▁common ▁D AMP s ▁ancest ral ▁sub family ▁and ▁were ▁modified ▁by ▁the ▁inn ate ▁imm une ▁system ▁to ▁stim ulate ▁imm une ▁response ▁in ▁addition ▁to ▁cell ▁damage ▁repair . ▁In ▁addition , ▁the ▁D AMP s ▁model ▁suggests ▁that ▁the ▁early ▁imm une ▁system ▁evol ved ▁from ▁an ▁ancient ▁damage ▁response ▁init iation ▁path way ▁directed ▁by ▁the ▁presence ▁of ▁hy pp os . ▁From ▁the ▁similar ities ▁between ▁PA MP s , ▁alarm ins , ▁and ▁D AMP s ▁as ▁well ▁as ▁the