, ▁" A ▁Success ful ▁Trans ition ▁to ▁sul fon am ides ▁treatment ▁in ▁male ▁infant ▁with ▁novel ▁ne on atal ▁di ab etes ▁m ell it us ▁( ND M ) ▁caused ▁by ▁the ▁AB BC 8 ▁gene ▁mut ation ▁and ▁ 3 ▁years ▁follow ▁up ". ▁It ▁is ▁a ▁case ▁study ▁on ▁the ▁transition ing ▁of ▁treat ments ▁from ▁ins ul in ▁ther apy ▁to ▁sul fon am ides ▁ther apy . ▁N DM ▁is ▁not ▁initi ated ▁by ▁an ▁auto imm une ▁mechanism ▁but ▁mut ations ▁in ▁K AT P - sens itive ▁channel , ▁K CN J 1 1 , ▁AB CC 8 ▁and ▁IN S ▁gen es ▁are ▁successful ▁targets ▁for ▁changing ▁treat ments ▁from ▁ins ul in ▁to ▁sul fon am ides ▁ther apy . ▁▁ ▁Introduction : ▁Within ▁this ▁study ▁ ▁a ▁two ▁month ▁old ▁male ▁was ▁admitted ▁into ▁the ▁int ensive ▁care ▁unit , ▁because ▁he ▁was ▁showing ▁signs ▁of ▁di ab etic ▁k eto ac idos is . ▁Other ▁sympt oms ▁include , ▁resp ir atory ▁tract ▁in fection , ▁sp orous , ▁de h yd r ation , ▁reduced ▁sub cut aneous ▁fat , ▁Cand ida ▁m uc ous ▁in fection . ▁The ▁infant ' s ▁family ▁history ▁was ▁negative ▁for ▁dise ases ▁of ▁importance ▁to ▁her edit ary ▁and ▁the ▁el dest ▁sib ling ▁was ▁health y . ▁ ▁Ex periment : ▁The ▁current ▁treatment ▁plan ▁consist ▁of ▁ther apy ▁for ▁k eto ac idos is ▁was ▁started ▁upon ▁adm issions ▁into