▁María ▁de ▁Villa c ís ▁y ▁Lo y ola , ▁he ▁founded ▁the ▁Major at ▁of ▁Villa cis ▁in ▁Gu ach al á . ▁On ▁October ▁ 2 7 , ▁ 1 6 6 0 , ▁P ich in cha ▁Vol cano ▁er upt ed , ▁causing ▁dis aster ▁in ▁all ▁cro ps ▁in ▁the ▁region ▁as ▁a ▁result ▁of ▁their ▁being ▁covered ▁under ▁vol can ic ▁ash . ▁ ▁After ▁Francisco ▁de ▁Villa c ís ' ▁death ▁on ▁ 1 6 7 9 , ▁María ▁inherited ▁the ▁ha ci enda ▁and ▁married ▁captain ▁Antonio ▁de ▁Or ma za ▁y ▁P once ▁de ▁León . ▁In ▁ 1 6 9 7 ▁the ▁latter ▁purchased ▁the ▁Ha ci enda ▁P amb amar ca ▁from ▁the ▁Pres by ter ian ▁Fernando ▁Santos ▁del ▁Est o que , ▁un ifying ▁both ▁ha ci end as ▁under ▁the ▁name ▁of ▁Gu ach al á . ▁In ▁ 1 6 9 8 ▁Antonio ▁obtained ▁a ▁license ▁allowing ▁text ile ▁production ▁that ▁would ▁be ▁export ed , ▁mainly ▁to ▁Lima , ▁Sant afé ▁de ▁Bog ot á ▁and ▁Spain . ▁ ▁Vis it ▁of ▁the ▁French ▁Ge odes ic ▁Mission ▁▁ ▁In ▁ 1 7 3 6 ▁the ▁French ▁Ge odes ic ▁Mission ▁led ▁by ▁La ▁Cond am ine ▁and ▁Jorge ▁Juan ▁y ▁Antonio ▁de ▁Ul lo a ▁came ▁to ▁E cuador ▁in ▁representation ▁of ▁Spain . ▁It ▁is ▁not ▁certainly ▁known ▁if ▁La ▁Cond am ine ▁stayed ▁at ▁Gu ach al á , ▁but ▁it ▁is ▁confirmed ▁that