ic ▁der mat itis . ▁In ▁path ological ▁conditions ▁and ▁cases ▁of ▁cell ▁damage ▁the ▁concentration ▁of ▁exposed ▁hy pp os ▁in ▁t issue ▁micro environment ▁is ▁too ▁great ▁to ▁be ▁resolved ▁by ▁activity ▁of ▁qu en ch ers . ▁When ▁exposed ▁to ▁a que ous ▁conditions ▁hy pp os ▁incorrectly ▁aggregate ▁with ▁one ▁another ▁through ▁hydro ph ob ic ▁interactions ▁resulting ▁in ▁potentially ▁to xic ▁prote ins ▁and ▁activation ▁of ▁inn ate ▁imm une ▁response ▁resulting ▁in ▁infl amm ation . ▁Thus , ▁constantly ▁elev ated ▁hy ppo ▁levels ▁can ▁lead ▁to ▁chron ic ▁infl amm ation . ▁The ▁goal ▁of ▁his ▁study ▁into ▁dise ases ▁potentially ▁caused ▁by ▁hy pp os ▁is ▁to ▁examine ▁the ▁th era pe ut ic ▁potential ▁of ▁hy ppo - qu en ch ers ▁for ▁treatment ▁of ▁infl am mat ory ▁dise ases ▁based ▁on ▁his ▁hypothesis ▁that ▁hy ppo - qu en ch ers ▁might ▁have ▁evol ved ▁as ▁an ▁imm une ▁mod ulator . ▁Rec ently , ▁he ▁is ▁carrying ▁out ▁phase ▁I ▁clin ical ▁trial ▁for ▁At op ic ▁der mat itis ▁using ▁small ▁mole c ule ▁that ▁qu en ches ▁hy ppo ▁at ▁mic rom olar ▁concentration ▁and ▁reg ulate ▁infl amm ation ▁at ▁nan om olar ▁concentration ▁by ▁interact ing ▁with ▁G PC R 1 9 . ▁ ▁References ▁ ▁External ▁links ▁▁ ▁Fac ulty ▁page ▁at ▁the ▁Se oul ▁National ▁University ▁College ▁of ▁Medicine ▁▁ ▁Category : 1 9 6 0 s ▁birth s ▁Category : L iving ▁people ▁Category