▁results ▁have ▁been ▁widely ▁covered ▁in ▁the ▁media ; ▁future ▁studies ▁will ▁look ▁at ▁modifying ▁( low ering ) ▁the ▁do se ▁( to ▁reduce ▁risk ▁associated ▁with ▁the ▁high ▁dos age ▁of ▁AS A ). ▁ ▁Screen ing ▁Gen etic ▁coun sel ing ▁and ▁gen etic ▁testing ▁are ▁recommended ▁for ▁families ▁that ▁meet ▁the ▁Amsterdam ▁criteria , ▁prefer ably ▁before ▁the ▁on set ▁of ▁colon ▁cancer . ▁ ▁A ▁trans v ag inal ▁ul tras ound ▁with ▁or ▁without ▁end omet rial ▁bi ops y ▁is ▁recommended ▁ann ually ▁for ▁o var ian ▁and ▁end omet rial ▁cancer ▁screen ing . ▁ ▁Amsterdam ▁criteria ▁The ▁following ▁are ▁the ▁Amsterdam ▁criteria ▁in ▁ident ifying ▁high - ris k ▁candidates ▁for ▁mole cular ▁gen etic ▁testing : ▁ ▁Amsterdam ▁I ▁C riteria ▁( all ▁bullet ▁points ▁must ▁be ▁ful filled ): ▁The ▁Amsterdam ▁I ▁criteria ▁were ▁published ▁in ▁ 1 9 9 0 ; ▁however , ▁were ▁felt ▁to ▁be ▁ins u fficient ly ▁sensitive . ▁Three ▁or ▁more ▁family ▁members ▁with ▁a ▁confirmed ▁diagn osis ▁of ▁col ore ct al ▁cancer , ▁one ▁of ▁whom ▁is ▁a ▁first ▁degree ▁( parent , ▁child , ▁sib ling ) ▁relative ▁of ▁the ▁other ▁two ▁Two ▁success ive ▁affected ▁gener ations ▁One ▁or ▁more ▁colon ▁can cers ▁diagn osed ▁under ▁age ▁ 5 0 ▁years ▁Famil ial ▁ad en om at ous ▁poly pos is ▁( F AP ) ▁has ▁been ▁ex cluded ▁ ▁The ▁Amsterdam ▁II ▁criteria ▁were ▁developed ▁in ▁ 1 9 9 9