ne , ▁excess ive ▁hair ▁growth , ▁and ▁voice ▁deep ening . ▁Dan az ol ▁has ▁a ▁complex ▁mechanism ▁of ▁action , ▁and ▁is ▁character ized ▁as ▁a ▁weak ▁and ro gen ▁and ▁an abol ic ▁ster oid , ▁a ▁weak ▁pro gest ogen , ▁a ▁weak ▁ant ig on ad otrop in , ▁a ▁weak ▁ster oid ogen esis ▁in hib itor , ▁and ▁a ▁functional ▁anti estro gen . ▁ ▁Dan az ol ▁was ▁discovered ▁in ▁ 1 9 6 3 ▁and ▁was ▁introduced ▁for ▁medical ▁use ▁in ▁ 1 9 7 1 . ▁Due ▁to ▁their ▁improved ▁side - effect ▁profiles , ▁particularly ▁their ▁lack ▁of ▁mascul in izing ▁side ▁effects , ▁dan az ol ▁has ▁largely ▁been ▁replaced ▁by ▁g on ad otrop in - re le asing ▁h orm one ▁analog ues ▁( G n R H ▁analog ues ) ▁in ▁the ▁treatment ▁of ▁end omet rios is . ▁ ▁Medical ▁uses ▁Dan az ol ▁is ▁used ▁primarily ▁in ▁the ▁treatment ▁of ▁end omet rios is . ▁It ▁has ▁also ▁been ▁used ▁– ▁mostly ▁off - label ▁– ▁for ▁other ▁indic ations , ▁namely ▁in ▁the ▁management ▁of ▁menor rh ag ia , ▁fib roc yst ic ▁breast ▁disease , ▁imm une ▁th rom b oc yt open ic ▁pur p ura , ▁pre men stru al ▁synd rome , ▁breast ▁pain , ▁and ▁her edit ary ▁ang io ed ema . ▁Although ▁not ▁currently ▁a ▁standard ▁treatment ▁for ▁menor rh ag ia , ▁dan az ol ▁demonstrated