uro to x ins , ▁and ▁reduces ▁ad hes ion ▁to ▁end oth el ial ▁cells . ▁ ▁The ▁most ▁common ▁treatment ▁is ▁h orm one ▁replacement ▁ther apy ▁or ▁est ro gen ▁ther apy . ▁Women ▁using ▁h orm one ▁ther apy ▁for ▁at ▁least ▁two ▁years ▁have ▁increased ▁blood ▁flow ▁to ▁the ▁hi pp oc amp us ▁and ▁temporal ▁lo be ▁as ▁compared ▁to ▁those ▁who ▁did ▁not ▁under go ▁ther apy . ▁These ▁areas ▁of ▁the ▁brain ▁are ▁key ▁to ▁memory . ▁Also , ▁women ▁who ▁do ▁not ▁under go ▁ther apy ▁have ▁been ▁found ▁to ▁have ▁less ▁met abol ic ▁activity ▁in ▁the ▁posterior ▁c ing ulate ▁cor tex , ▁while ▁those ▁with ▁est ro gen ▁ther apy ▁did ▁not ▁show ▁a ▁significant ▁met abol ic ▁change . ▁ ▁This ▁is ▁important ▁as ▁decl ines ▁in ▁c ere br al ▁met abol ism ▁occur ▁in ▁the ▁early ▁stages ▁of ▁Al z heimer ' s , ▁as ▁mentioned ▁in ▁" C aus es ". ▁Women ▁who ▁had ▁their ▁u ter us ▁and ▁o var ies ▁removed ▁for ▁medical ▁reasons ▁and ▁lost ▁their ▁g on adal ▁h orm ones ▁showed ▁a ▁decrease ▁in ▁short - term ▁ver bal ▁( hi pp oc amp us ) ▁and ▁working ▁mem ories ▁( pre - front al ▁cor tex ), ▁yet ▁with ▁est ro gen ▁ther apy ▁the ▁memory ▁loss ▁was ▁prevent ed . ▁ ▁Furthermore , ▁those ▁who ▁have ▁undert aken ▁est ro gen ▁ther apy ▁have ▁shown ▁significantly ▁higher ▁scores ▁on ▁ver