▁NK ▁cell ▁development . ▁ ▁In ▁rod ent ▁l ym ph ocy tes , ▁IL - 1 5 ▁prevents ▁apo pt osis ▁by ▁indu cing ▁B CL 2 L 1 / BC L - x ( L ), ▁an ▁in hib itor ▁of ▁the ▁apo pt osis ▁path way . ▁In ▁humans ▁with ▁cel iac ▁disease ▁IL - 1 5 ▁similarly ▁suppress es ▁apo pt osis ▁in ▁T - ly m ph ocy tes ▁by ▁indu cing ▁B cl - 2 ▁and / or ▁B cl - x L . ▁ ▁A ▁h emat opo iet in ▁re ceptor , ▁the ▁IL - 1 5 ▁re ceptor , ▁that ▁bind s ▁IL - 1 5 ▁propag ates ▁its ▁function . ▁ ▁Some ▁sub un its ▁of ▁the ▁IL - 1 5 ▁re ceptor ▁are ▁shared ▁in ▁common ▁with ▁the ▁re ceptor ▁for ▁a ▁struct ur ally ▁related ▁cy tok ine ▁called ▁Inter le uk in ▁ 2 ▁( IL - 2 ) ▁allowing ▁both ▁cy tok ines ▁to ▁comp ete ▁for ▁and ▁neg atively ▁reg ulate ▁each ▁other ' s ▁activity . ▁ ▁CD 8 + ▁memory ▁T ▁cell ▁number ▁is ▁controlled ▁by ▁a ▁balance ▁between ▁IL - 1 5 ▁and ▁IL - 2 . ▁ ▁When ▁IL - 1 5 ▁bind s ▁its ▁re ceptor , ▁J AK ▁kin ase , ▁ST AT 3 , ▁ST AT 5 , ▁and ▁ST AT 6 ▁trans cription ▁factors ▁are ▁activ ated ▁to ▁el ic it ▁down stream ▁signal ing ▁events . ▁ ▁IL -