▁the ▁Arch bishop ▁was ▁appointed ▁by ▁his ▁will ▁as ▁Lieutenant ▁General ▁of ▁Arag on ▁and ▁de ▁fact o ▁r uler ▁of ▁Arag on , ▁due ▁to ▁the ▁ins an ity ▁of ▁his ▁half - s ister , ▁Queen ▁Jo anna , ▁who ▁inherited ▁the ▁crown . ▁When ▁Jo anna ' s ▁son ▁and ▁co - r uler , ▁Charles ▁I , ▁arrived ▁in ▁November ▁ 1 5 1 8 , ▁the ▁Arch bishop ▁was ▁confirmed ▁as ▁Lieutenant ▁General ▁of ▁Arag on . ▁He ▁died ▁two ▁years ▁later ▁in ▁L éc era . ▁ ▁Arag ón ▁also ▁real ised ▁important ▁modifications ▁on ▁the ▁La ▁Se o ▁C athedral , ▁where ▁he ▁was ▁buried . ▁ ▁Issue ▁ ▁Despite ▁being ▁Arch bishop , ▁Al onso ▁had ▁seven ▁children ▁with ▁Ana ▁de ▁G ur rea ▁( 1 4 7 0 – 1 5 2 7 ), ▁including : ▁▁ ▁Juan ▁( 1 4 9 8 – 1 5 3 0 ), ▁next ▁Arch bishop ▁of ▁Zar ago za ▁ ▁Hern ando ▁( 1 4 9 8 – 1 5 7 5 ), ▁also ▁Arch bishop ▁of ▁Zar ago za ▁and ▁Vic ero y ▁of ▁Arag ón ▁ ▁Antonio ▁( d ied ▁ 1 5 5 2 ), ▁Lord ▁of ▁Qu into ▁ ▁Ju ana ▁( d ied ▁ 1 5 2 0 ), ▁married ▁to ▁Juan ▁de ▁Bor ja , ▁ 3 rd ▁Duke ▁of ▁Gand ía ▁and ▁mother ▁of ▁Saint ▁Francis ▁Borg ia ▁ ▁Martin , ▁Lord ▁of ▁Arg av ies o ▁ ▁Ana ,