▁human ▁primary ▁visual ▁cor tex . ▁ ▁Bus se ▁was ▁then ▁ready ▁to ▁move ▁her ▁experiments ▁into ▁m ice , ▁a ▁common ▁model ▁organ ism ▁is ▁systems ▁neu ros cience ▁to ▁dis sect ▁neural ▁circ uits , ▁but ▁she ▁first ▁had ▁to ▁pione er ▁a ▁new ▁approach ▁to ▁be ▁able ▁to ▁relate ▁vision ▁circ uits ▁to ▁per ception ▁in ▁m ice . ▁Bus se ▁extens ively ▁trained ▁m ice ▁to ▁detect ▁visual ▁contrast ▁using ▁trial - based ▁oper ant ▁condition ing . ▁After ▁extensive ▁training , ▁they ▁found ▁that ▁choices ▁m ice ▁made ▁in ▁this ▁oper ant ▁task ▁were ▁not ▁only ▁based ▁on ▁the ▁learned ▁contrast ▁association ▁but ▁also ▁factors ▁such ▁as ▁reward ▁value ▁or ▁recent ▁fail ures . ▁When ▁they ▁used ▁a ▁generalized ▁linear ▁model ▁to ▁decode ▁the ▁neural ▁data ▁to ▁predict ▁behavior al ▁outputs , ▁they ▁found ▁that ▁the ▁dec oder ▁performed ▁better ▁than ▁the ▁mouse ▁suggesting ▁that ▁the ▁mouse ▁might ▁not ▁be ▁using ▁the ▁V 1 ▁information ▁in ▁the ▁most ▁optimal ▁way . ▁ ▁Career ▁and ▁Research ▁ ▁In ▁ 2 0 1 0 , ▁Bus se ▁became ▁a ▁Junior ▁Research ▁Group ▁Le ader ▁in ▁the ▁Werner ▁Reich ard t ▁Center ▁for ▁Integr ative ▁Neu ros cience ▁at ▁the ▁University ▁of ▁T üb ingen , ▁in ▁Germany . ▁She ▁lead ▁a ▁team ▁of ▁research ers ▁to ▁approach ▁studying ▁the ▁visual ▁stim uli ▁in ▁an ▁eth olog ically ▁relevant ▁way . ▁Since ▁visual ▁systems ▁are ▁designed ▁to ▁reflect ▁an ▁organ isms ▁environment , ▁Bus se ▁sh aped ▁her ▁research ▁program ▁around