▁in ▁countries ▁with ▁food ▁containing ▁a ▁significant ▁amount ▁of ▁add it ives ▁to ▁their ▁food ▁( es pecially ▁da iry ), ▁like ▁the ▁United ▁States ▁and ▁some ▁European ▁countries , ▁excess ive ▁I G F ▁levels ▁occur ▁in ▁order ▁to ▁prevent ▁ph osph ot ox icity . ▁ ▁When ▁an ▁individual ▁absor bs ▁ph osph ate ▁from ▁food s ▁that ▁are ▁high ▁in ▁its ▁bio av ail ability , ▁the ▁b one ▁up reg ul ates ▁F G F 2 3 ▁production ▁to ▁indu ce ▁greater ▁ur inary ▁ex cret ion ▁of ▁ph osph ate ▁and ▁minim izing ▁the ▁efficiency ▁of ▁int est inal ▁ph osph ate ▁absor ption ▁by ▁reducing ▁ser um ▁ 1 - 2 5 - d ih ydro xy v it amin ▁D ▁levels . ▁This ▁reduces ▁the ▁amount ▁of ▁Vit aman ▁D , ▁or ▁ 1 - 2 5 - d ih ydro xy v it amin ▁D ., ▁and ▁this ▁results ▁in ▁a ▁numerous ▁amount ▁of ▁end ocr ine ▁issues , ▁like ▁thy roid ▁disease , ▁excess ive ▁infl amm ation , ▁like ▁fib ros is ▁of ▁the ▁l ungs , ▁and ▁Ren al ▁Kid ney ▁D ise ase ▁( R K D ) ▁or ▁Hyper ph osph atem ia . ▁▁▁ ▁Wang ' s ▁work ▁connected ▁high ▁levels ▁of ▁I G F ▁to ▁the ▁l ungs ▁over re action ▁to ▁vir uses , ▁like ▁a ▁coron av irus , ▁which ▁involves ▁excess ive ▁infl amm ation ▁and ▁resulting ▁Ac ute ▁Res p ir atory ▁Dist ress