▁chron ic ▁infl amm ation ▁has ▁been ▁shown ▁to ▁affect ▁chief ▁cell ▁different iation ▁and ▁can ▁indu ce ▁chief ▁cells ▁to ▁trans d iffer enti ate ▁back ▁into ▁neck ▁cells ▁and ▁can ▁lead ▁to ▁the ▁formation ▁of ▁m uc us ▁cell ▁met ap las ia ▁known ▁as ▁sp asm ol yt ic ▁pol ype pt ide ▁express ing ▁met ap las ia ▁( S PE M ) ▁that ▁could ▁be ▁pre can cer ous . ▁If ▁par iet al ▁cells ▁are ▁lost , ▁m ature ▁chief ▁cells ▁do ▁not ▁form . ▁P ari etal ▁cells ▁may ▁se crete ▁factors ▁that ▁lead ▁to ▁trans d iffer enti ation ▁of ▁chief ▁cells , ▁so ▁if ▁lost , ▁chief ▁cells ▁do ▁not ▁normally ▁develop . ▁ ▁References ▁ ▁Category : Cell ▁bi ology <0x0A> </s> ▁The ▁Z yg oc yst inae ▁are ▁a ▁sub family ▁of ▁par as ites ▁in ▁the ▁ph yl um ▁Ap ic om plex a . ▁ ▁Tax onomy ▁ ▁There ▁are ▁three ▁gener a ▁in ▁this ▁sub family : ▁Adel ph oc yst is , ▁Ple uro c yst is ▁and ▁Z yg oc yst is . ▁ ▁History ▁ ▁This ▁family ▁was ▁created ▁by ▁B hat ia ▁in ▁ 1 9 3 0 . ▁ ▁Description ▁ ▁Species ▁in ▁this ▁sub family ▁inf ect ▁w orm s ▁of ▁the ▁family ▁L um br ic idae . ▁▁ ▁In ▁these ▁gener a ▁sy zy gy ▁occurs ▁extremely ▁early ▁in ▁the ▁life ▁cycle . ▁ ▁The ▁o oc yst ▁is ▁nav icular