lation . ▁This ▁indirect ▁method ▁is ▁often ▁used ▁because ▁ar yl ▁hal ides ▁are ▁relatively ▁we aker ▁nucle oph iles ▁than ▁ali ph atic ▁hal oc ar b ons ▁and ▁thus ▁poor ly ▁alk yl ate ▁di eth yl ▁mal on ate . ▁Method s ▁using ▁Ca es ium ▁carbon ate ▁and ▁co pper ( I ) ▁i od ide ▁have ▁been ▁developed ▁to ▁overcome ▁this ▁difficulty ▁however . ▁ ▁References ▁ ▁Category : Mal on ates ▁Category : B enz ene ▁derivatives ▁Category : E th yl ▁est ers <0x0A> </s> ▁The ▁Grand ▁High ▁W itch ▁of ▁All ▁The ▁World , ▁or ▁just ▁the ▁Grand ▁High ▁W itch , ▁known ▁as ▁Eva ▁Ernst ▁in ▁the ▁ 1 9 9 0 ▁film , ▁is ▁a ▁fict ional ▁character ▁and ▁the ▁main ▁ant agon ist ▁in ▁Ro ald ▁D ahl ' s ▁ 1 9 8 3 ▁children ' s ▁fant asy ▁novel ▁The ▁W itch es , ▁as ▁well ▁as ▁its ▁film ▁adaptation ▁in ▁which ▁she ▁is ▁played ▁by ▁An jel ica ▁H ust on . ▁In ▁the ▁narr ative , ▁it ▁is ▁a ▁title ▁given ▁to ▁the ▁all - power ful ▁leader ▁of ▁all ▁the ▁w itch es ▁on ▁Earth . ▁ ▁The ▁novel ▁presents ▁her ▁as ▁a ▁particularly ▁powerful , ▁evil ▁and ▁fe ared ▁w itch ▁who ▁h ides ▁her ▁ancient ▁age ▁and ▁hide ous ▁appearance ▁behind ▁an ▁attract ive ▁dis gu ise ▁in ▁order ▁to ▁bl end ▁in ▁with ▁society , ▁and ▁plots ▁to ▁w ipe ▁out ▁all ▁the ▁children