▁addition ▁to ▁Canada ' s ▁routine , ▁domestic ▁imm un ization ▁needs , ▁demand ▁for ▁Con n aught ' s ▁small po x ▁v acc ine ▁had ▁expanded ▁through ▁the ▁war ▁years ▁given ▁military ▁needs ▁and ▁the ▁growing ▁scale ▁of ▁trans n ational ▁medical ▁operations . ▁Sim ult ane ously , ▁the ▁ph arma ce ut ical ▁industry ▁was ▁dr ast ically ▁transformed ▁by ▁such ▁inter link ed ▁factors ▁as ▁the ▁post - war ▁bo om , ▁factory - based ▁mass - production , ▁increased ▁bar riers ▁to ▁entry , ▁and ▁heavy ▁cons olid ation ▁of ▁private ▁industry ▁( in ▁ 1 9 5 1 ▁alone , ▁Pf izer ▁opened ▁subs idi aries ▁in ▁nine ▁new ▁countries ). ▁Small ▁domestic ▁produ cers ▁fell ▁under ▁foreign ▁control ▁as ▁they ▁were ▁unable ▁to ▁comp ete ▁on ▁the ▁scale ▁demanded ▁by ▁the ▁new ▁technology . ▁Given ▁these ▁develop ments , ▁by ▁the ▁ 1 9 5 0 s ▁the ▁L abs ' ▁leadership ▁saw ▁a ▁necessary ▁and ▁advantage ous ▁n iche ▁in ▁the ▁growing ▁international ▁market ▁for ▁the ▁small po x ▁v acc ine . ▁ ▁To ▁meet ▁dem ands ▁for ▁transport ability ▁and ▁a ▁longer ▁sh elf - life , ▁Con n aught ▁began ▁its ▁efforts ▁to ▁produce ▁a ▁d ried ▁version ▁of ▁the ▁v acc ine ▁under ▁C lee ve ▁R . ▁Am ies , ▁previously ▁of ▁the ▁L ister ▁Institute . ▁In ▁ 1 9 6 7 , ▁the ▁institution ▁entered ▁into ▁formal ▁collaboration ▁with ▁the ▁World ▁Health ▁Organ ization ▁( W HO