1 - 1 0 5 , ▁ 1 0 6 - 1 5 7 , ▁ 1 5 8 - 2 2 5 , ▁and ▁ 2 2 6 - 5 1 9 ). ▁ ▁Prote in ▁ ▁Phys ical ▁features ▁ ▁SM IM 2 3 ▁not ably ▁has ▁a ▁transm emb rane ▁domain . ▁ ▁The ▁predicted ▁is oe lect ric ▁point ▁for ▁the ▁un mod ified / un process ed ▁protein ▁in ▁m ice ▁is ▁ 5 . 7 7 9 ▁while ▁only ▁the ▁transm emb rane ▁region ▁in ▁humans ▁has ▁an ▁is oe lect ric ▁point ▁of ▁ 5 . 9 2 8 ▁ ▁The ▁gene ▁appears ▁to ▁be ▁Le uc ine ▁and ▁Gl ut am ic ▁Ac id ▁rich ▁though ▁not ▁at ▁any ▁usually ▁high ▁number . ▁It ▁is ▁also ▁weak ▁in ▁all ▁other ▁am ino ▁ac ids ▁besides ▁Alan ine , ▁Ser ine , ▁and ▁Gl ut am ine . ▁ ▁The ▁region ▁under lined ▁in ▁the ▁concept ual ▁translation ▁was ▁predicted ▁to ▁be ▁an ▁In vol uc rin ▁repeat . ▁ ▁Post - Trans l ational ▁modifications ▁ ▁The ▁transm emb rane ▁region ▁is ▁ 1 6 7 4 . 2 ▁D alt ons ▁while ▁the ▁whole ▁protein ▁is ▁ 2 0 0 0 0 8 . 5 1 ▁Da . ▁This ▁is ▁very ▁similar ▁to ▁what ▁was ▁found ▁with ▁Un i Pro t ▁where ▁predicted ▁mole cular ▁weight ▁was ▁ 2 0 . 0 2 5 ▁k Da . ▁Ant ib ody ▁k its ▁were ▁investig