al ies . ▁No ▁important ▁differences ▁in ▁the ▁frequency ▁of ▁e ct op ic ▁pre gn an cies ▁and ▁mis car riage ▁were ▁noted ▁with ▁the ▁use ▁of ▁gan ire li x . ▁ ▁Inter actions ▁▁ ▁Currently , ▁no ▁studies ▁have ▁been ▁done ▁to ▁assess ▁the ▁possible ▁drug - d rug ▁interactions ▁between ▁gan ire li x ▁and ▁other ▁dru gs . ▁ ▁Ph arm ac ology ▁ ▁Ph arm ac od ynam ics ▁Gan ier li x ▁is ▁a ▁synth etic ▁pe pt ide ▁that ▁works ▁as ▁an ▁ant agon ist ▁against ▁g on ad otrop in - re le asing ▁h orm one ▁( G n R H ) ▁(" G an ire li x ▁ac et ate ▁injection ," ▁ 2 0 0 9 ). ▁Gan ire li x ▁compet it ively ▁blocks ▁G n R H ▁re cept ors ▁on ▁the ▁p itu it ary ▁g on ad ot roph , ▁quickly ▁resulting ▁in ▁the ▁supp ression ▁of ▁g on ad otrop in ▁secret ion . ▁This ▁supp ression ▁is ▁easily ▁revers ed ▁by ▁dis continu ation ▁of ▁gan ire li x ▁administration . ▁Gan ire li x ▁has ▁a ▁significantly ▁higher ▁re ceptor ▁binding ▁aff inity ▁( K d ▁= ▁ 0 . 4 ▁n M ) ▁than ▁G n R H ▁( K d ▁= ▁ 3 . 6 ▁n M ). ▁ ▁Ph arm ac ok inet ics ▁When ▁gan ire li x ▁is ▁given ▁to ▁health y ▁adult ▁females , ▁steady - state ▁ser