▁Eth amb ut ol / ison ia z id / py raz in am ide / rif amp ic in ▁ ▁Hy os cy am ine / hex am eth y len et et ram ine / phen yl ▁sal ic yl ate / m eth yl ene ▁blue / ben zo ic ▁acid ▁ ▁Adv antages ▁ ▁In ▁addition ▁to ▁simply ▁being ▁a ▁means ▁of ▁facil it ating ▁the ▁general ▁advantages ▁of ▁combination ▁ther apy , ▁specific ▁advantages ▁of ▁fixed - d ose ▁combination ▁( F DC ) ▁drug ▁products ▁include : ▁ ▁Im pro ved ▁medic ation ▁comp liance ▁by ▁reducing ▁the ▁pill ▁bur den ▁of ▁patients . ▁Note ▁that ▁pill ▁bur den ▁is ▁not ▁only ▁the ▁number ▁of ▁p ills ▁need ing ▁to ▁be ▁taken , ▁but ▁also ▁the ▁associated ▁bur dens ▁such ▁as ▁keeping ▁track ▁of ▁several ▁medic ations , ▁understanding ▁their ▁various ▁instructions , ▁etc . ▁Ab ility ▁to ▁compose ▁combined ▁profiles ▁of ▁for ▁example ▁ph arm ac ok inet ics , ▁effects ▁and ▁ad verse ▁effects ▁that ▁may ▁be ▁specific ▁for ▁the ▁relative ▁dos ages ▁in ▁a ▁given ▁F DC ▁product , ▁providing ▁a ▁simpler ▁over view ▁compared ▁to ▁when ▁looking ▁at ▁the ▁profiles ▁of ▁each ▁single ▁drug ▁individually . ▁Such ▁combined ▁profiles ▁can ▁also ▁include ▁effects ▁caused ▁by ▁interaction ▁between ▁the ▁individual ▁dru gs ▁that ▁may ▁be ▁omitted ▁in ▁individual ▁drug ▁profiles . ▁Since ▁F DC s ▁are ▁review ed ▁by ▁reg ulating ▁ag encies ▁( such ▁as ▁the ▁Food ▁and ▁D rug ▁Administration ▁in ▁the