▁blood ▁cells ▁rather ▁than ▁b icon ca ve . ▁Because ▁spher ical ▁red ▁blood ▁cells ▁are ▁more ▁pr one ▁to ▁l ysis ▁in ▁water ▁( because ▁the ▁lack ▁some ▁prote ins ▁in ▁their ▁c yt os ke leton ) ▁there ▁will ▁be ▁increased ▁os m otic ▁frag ility ▁on ▁acid ified ▁g ly cer ol ▁l ysis ▁test . ▁ ▁Tre at ment ▁Tre at ment ▁may ▁vary ▁depending ▁on ▁the ▁cause ▁of ▁the ▁condition . ▁In ▁the ▁case ▁of ▁her edit ary ▁spher oc yt osis , ▁although ▁research ▁is ▁on going , ▁at ▁this ▁point ▁there ▁is ▁no ▁c ure ▁for ▁the ▁gen etic ▁defect ▁that ▁causes ▁her edit ary ▁spher oc yt osis . ▁Current ▁management ▁focus es ▁on ▁inter vent ions ▁that ▁limit ▁the ▁sever ity ▁of ▁the ▁disease . ▁ ▁Tre at ment ▁options ▁for ▁this ▁type ▁of ▁spher oc yt osis ▁include : ▁▁ ▁S pl en ect omy : ▁As ▁in ▁non - her edit ary ▁spher oc yt osis , ▁ac ute ▁sympt oms ▁of ▁an emia ▁and ▁hyper bil ir ub in emia ▁indicate ▁treatment ▁with ▁blood ▁trans f us ions ▁or ▁ex changes ▁and ▁chron ic ▁sympt oms ▁of ▁an emia ▁and ▁an ▁en larg ed ▁s ple en ▁indicate ▁di et ary ▁supp lement ation ▁of ▁fol ic ▁acid ▁and ▁spl en ect omy , ▁the ▁surg ical ▁removal ▁of ▁the ▁s ple en . ▁S pl en ect omy ▁is ▁indicated ▁for ▁moder ate ▁to ▁severe ▁cases , ▁but ▁not ▁m