▁is ▁predicted ▁to ▁be ▁found ▁in ▁the ▁end op las mic ▁ret icul um . ▁The ▁same ▁kind ▁of ▁investigation ▁of ▁protein ▁local ization ▁in ▁other ▁types ▁of ▁species ▁returned ▁conflic ting ▁results . ▁Many ▁programs ▁predicted ▁the ▁protein ▁to ▁be ▁present ▁in ▁the ▁c yt os ol . ▁This ▁suggests ▁the ▁possibility ▁of ▁incorrect ▁naming , ▁i . e . ▁the ▁protein ▁may ▁not ▁be ▁integral ▁memb rane ▁due ▁to ▁other ▁predicted ▁locations . ▁This ▁type ▁of ▁conclusion ▁will ▁require ▁further ▁information . ▁ ▁Expression ▁ ▁Not ▁enough ▁cons ensus ▁exists ▁as ▁to ▁where ▁in ▁the ▁body ▁SM IM 2 3 ▁is ▁expressed . ▁Dat ab ases ▁indicate ▁mainly ▁in ▁the ▁test es , ▁but ▁this ▁may ▁be ▁due ▁to ▁the ▁lack ▁of ▁data . ▁ ▁Reg ulation ▁of ▁Expression ▁ ▁The ▁prom oter ▁region ▁of ▁SM IM 2 3 ▁is ▁approximately ▁ 1 1 9 2 ▁nucle ot ides ▁long ▁with ▁various ▁predicted ▁trans cription ▁factors . ▁ ▁Reg ulation ▁in ▁the ▁secondary ▁structure ▁is ▁a ▁predicted ▁stem - loop ▁in ▁the ▁ 5 ' ▁U TR ▁region ▁with ▁a ▁few ▁areas ▁of ▁conservation ▁across ▁species . ▁ ▁Function ▁and ▁clin ical ▁significance ▁Nov el ▁research ▁has ▁suggested ▁that ▁how ▁face ▁shape ▁ar ises ▁in ▁individuals ▁may ▁be ▁influenced ▁by ▁a ▁set ▁of ▁gen es . ▁This ▁set ▁includes ▁SM IM 2 3 . ▁Though ▁in ▁the ▁paper ▁the ▁gene ▁is ▁referred ▁to ▁by ▁an ▁alias ▁( C 5 orf 5 0 ), ▁it ▁is ▁clear ▁that ▁the ▁scient ists ▁have