▁of ▁Melbourne ' s ▁Central ▁Business ▁District , ▁located ▁within ▁the ▁Sh ires ▁of ▁B aw ▁B aw ▁and ▁Card in ia ▁local ▁government ▁areas . ▁Mod ella ▁recorded ▁a ▁population ▁of ▁ 1 4 8 ▁at ▁the ▁ 2 0 1 6 ▁Census . ▁ ▁History ▁ ▁Mod ella ▁Post ▁Office ▁opened ▁on ▁ 2 ▁December ▁ 1 9 0 4 ▁and ▁closed ▁in ▁ 1 9 6 2 . ▁ ▁References <0x0A> </s> ▁The ▁tub by ▁protein ▁is ▁encoded ▁by ▁the ▁T UB ▁gene . ▁ ▁It ▁is ▁an ▁up stream ▁cell ▁signal ing ▁protein ▁common ▁to ▁mult ic ell ular ▁e uk ary otes . ▁The ▁first ▁tub by ▁gene ▁was ▁identified ▁in ▁m ice , ▁and ▁prote ins ▁that ▁are ▁hom olog ous ▁to ▁tub by ▁are ▁known ▁as ▁" t ub by - like ▁prote ins " ▁( T U LP s ). ▁ ▁They ▁share ▁a ▁common ▁and ▁characteristic ▁t ert i ary ▁structure ▁that ▁consists ▁of ▁a ▁beta ▁bar rel ▁pack ed ▁around ▁an ▁alpha ▁hel ix ▁in ▁the ▁central ▁p ore . ▁The ▁gene ▁der ives ▁its ▁name ▁from ▁its ▁role ▁in ▁met abol ism ; ▁m ice ▁with ▁a ▁mut ated ▁tub by ▁gene ▁develop ▁delayed - ons et ▁ob es ity , ▁sensor ine ural ▁hearing ▁loss ▁and ▁ret inal ▁deg ener ation . ▁ ▁Str ucture ▁T ub by ▁prote ins ▁are ▁class ified ▁as ▁α + β ▁prote ins ▁and ▁have ▁a ▁ 1 2 - beta ▁str and ed ▁bar