▁for ear ms ▁with ▁general ▁weak ness ▁of ▁the ▁legs . ▁The ▁bow ing ▁of ▁the ▁legs ▁is ▁usually ▁seen ▁in ▁ad oles c ence , ▁with ▁the ▁child ▁often ▁taking ▁longer ▁than ▁average ▁to ▁walk . ▁The ▁increased ▁b one ▁density ▁manifest s ▁with ▁the ▁sk ull ▁with ▁general ▁w iden ing ▁of ▁dip lo ic ▁space . ▁Also , ▁a ▁thick ened ▁sk ull ▁base ▁suggests ▁dia phy se al ▁d ys pl asia , ▁which ▁can ▁lead ▁to ▁s cl eros is ▁of ▁the ▁base ▁of ▁the ▁sk ull . ▁ ▁When ▁it ▁comes ▁to ▁blood , ▁most ▁sympt oms ▁can ▁be ▁summar ized ▁as ▁defect ive ▁h emat opo ies is . ▁It ▁is ▁spec ulated ▁that ▁this ▁is ▁due ▁to ▁the ▁met ad ia phy se al ▁d ys pl asia ▁of ▁the ▁long ▁b ones ▁and ▁fib ros is ▁or ▁s cl eros is ▁of ▁the ▁b one ▁mar row . ▁The ▁sympt oms ▁can ▁include ▁cort ic ost ero id - sens itive ▁an emia , ▁th rom b oc yt open ia , ▁hyp oc ell ular ▁b one ▁mar row , ▁and ▁my el of ib ros is . ▁The ▁key ▁sympt om ▁here ▁is ▁progress ive ▁an emia , ▁and ▁sympt oms ▁like ▁th rom b oc yt open ia ▁or ▁le uk open ia ▁may ▁be ▁present ▁with ▁varying ▁degrees ▁of ▁pen et rance ▁between ▁patients . ▁ ▁C aus es ▁ ▁Gh os al ▁h emat odia phy se al ▁d