D ock ▁closely ▁agreed ▁with ▁the ▁especially ▁difficult - to - ob tain ▁experimental ▁models , ▁leading ▁research ers ▁to ▁conclude ▁that ▁the ▁dock ing ▁method ▁has ▁potential ▁to ▁address ▁some ▁of ▁the ▁problems ▁that ▁X - ray ▁cry stal log raph y ▁has ▁with ▁model ing ▁protein – prote in ▁interfaces . ▁ ▁H IV ▁ ▁As ▁part ▁of ▁research ▁fund ed ▁by ▁a ▁$ 1 9 . 4   mill ion ▁grant ▁by ▁the ▁Bill ▁& ▁Mel inda ▁G ates ▁Foundation , ▁Ros etta @ home ▁has ▁been ▁used ▁in ▁design ing ▁multiple ▁possible ▁v acc ines ▁for ▁human ▁imm un ode fic iency ▁virus ▁( H IV ). ▁ ▁Mal aria ▁ ▁In ▁research ▁involved ▁with ▁the ▁Grand ▁Ch alleng es ▁in ▁Global ▁Health ▁initi ative , ▁Ros etta ▁has ▁been ▁used ▁to ▁computation ally ▁design ▁novel ▁hom ing ▁end on uc lease ▁prote ins , ▁which ▁could ▁er ad icate ▁An oph eles ▁g amb iae ▁or ▁otherwise ▁render ▁the ▁mos qu ito ▁unable ▁to ▁transmit ▁mal aria . ▁Being ▁able ▁to ▁model ▁and ▁alter ▁protein – D NA ▁interactions ▁specifically , ▁like ▁those ▁of ▁hom ing ▁end on uc leases , ▁gives ▁computational ▁protein ▁design ▁methods ▁like ▁Ros etta ▁an ▁important ▁role ▁in ▁gene ▁ther apy ▁( which ▁includes ▁possible ▁cancer ▁treat ments ). ▁ ▁Other ▁dise ases ▁ ▁Ros etta @ home ▁research ers ▁have ▁designed ▁an ▁IL - 2 ▁re ceptor ▁ag on ist ▁called ▁Ne ole uk in - 2 / 1 5 ▁that ▁does