▁References ▁ ▁Category : F ant asy ▁role - play ing ▁game ▁advent ures ▁Category : Role ▁A ids ▁Category : Role - play ing ▁games ▁based ▁on ▁films <0x0A> </s> ▁Lub el uz ole ▁( Pro syn ap ) ▁is ▁a ▁drug ▁which ▁acts ▁as ▁an ▁indirect ▁N MD A ▁ant agon ist . ▁It ▁in hib its ▁the ▁release ▁of ▁gl ut am ate , ▁in hib its ▁nit ric ▁ox ide ▁synth esis , ▁and ▁blocks ▁calci um ▁and ▁sod ium ▁g ated ▁ion ▁channels . ▁It ▁has ▁ne uro prote ct ive ▁effects ▁particularly ▁in ▁hy po xic ▁conditions , ▁and ▁was ▁developed ▁for ▁the ▁treatment ▁of ▁stroke . ▁Tri als ▁showed ▁it ▁to ▁be ▁safe , ▁effective ▁and ▁well ▁toler ated ▁at ▁low ▁dos es , ▁but ▁unfortunately ▁higher ▁dos es ▁produced ▁the ▁dangerous ▁card iac ▁side ▁effect ▁of ▁length ening ▁the ▁Q T c ▁interval , ▁which ▁could ▁potentially ▁lead ▁to ▁heart ▁failure , ▁and ▁so ▁this ▁meant ▁that ▁subsequent ▁tri als ▁were ▁limited ▁to ▁using ▁only ▁the ▁low ▁do se ▁range . ▁Animal ▁studies ▁had ▁shown ▁lub el uz ole ▁to ▁produce ▁ne uro prote ct ive ▁effects ▁when ▁admin ister ed ▁for ▁prolong ed ▁periods , ▁but ▁the ▁aim ▁of ▁its ▁developers ▁was ▁to ▁produce ▁a ▁drug ▁that ▁would ▁be ▁effective ▁for ▁prevent ing ▁damage ▁from ▁ac ute ▁stroke , ▁and ▁so ▁ultimately ▁it ▁failed ▁to ▁show ▁sufficient ▁effic acy ▁in ▁tri als ▁and ▁development ▁for ▁medical ▁use ▁was ▁halt ed . ▁ ▁References ▁▁