▁the ▁low ▁repair ▁activity , ▁m ature ▁s per ms ▁are ▁in cap able ▁of ▁D SB ▁repair . ▁Additionally , ▁D SB ▁can ▁also ▁be ▁rep a ired ▁by ▁hom olog ous ▁recom bin ation ▁( HR ), ▁which ▁is ▁more ▁accurate ▁and ▁introdu ces ▁fewer ▁errors ▁in ▁the ▁process ▁of ▁repair , ▁while , ▁has ▁not ▁yet ▁seen ▁in ▁the ▁process ▁of ▁m t D NA ▁insert ion ; . ▁A part ▁from ▁canonical ▁N HE J , ▁D SB s ▁are ▁rep a ired ▁via ▁a ▁mechanism ▁that ▁involves ▁sequences ▁containing ▁a ▁few ▁hom olog ous ▁nucle ot ides ▁at ▁the ▁ends ▁of ▁a ▁D SB ▁to ▁be ▁lig ated . ▁This ▁mechanism ▁is ▁known ▁as ▁micro hom ology - medi ated ▁end ▁joining ▁abbre vi ated ▁as ▁M ME J . ▁M ME J ▁is ▁the ▁most ▁mut agen ic ▁D SB ▁repair ▁mechanism ▁due ▁to ▁generating ▁delet ions , ▁insert ion ▁of ▁various ▁sizes , ▁and ▁other ▁gen ome ▁re arr ang ements ▁in ▁m amm ali ans . ▁As ▁shown ▁in ▁figure ▁ 3 , ▁the ▁processes ▁of ▁m t D NA ▁insert ion ▁and ▁D SB ▁repair ▁include ▁few ▁steps ▁which ▁are ▁DNA ▁segment ▁alignment , ▁DNA ▁end - processing , ▁DNA ▁synth esis , ▁and ▁lig ation . ▁In ▁each ▁step , ▁certain ▁protein ▁complex es ▁are ▁required ▁to ▁facil itate ▁the ▁occurrence ▁of ▁the ▁indicated ▁events . ▁As ▁shown ▁in ▁figure ▁ 3 , ▁in ▁N HE J , ▁the ▁Ku 7 0 /