▁ 1 6 th ▁and ▁ 1 7 th ▁centuries , ▁thousands ▁of ▁Japanese ▁people ▁trad ers ▁also ▁migr ated ▁to ▁the ▁Philippines ▁and ▁assim il ated ▁into ▁the ▁local ▁population . ▁pp .   5 2 – 3 ▁ ▁In ▁ 1 5 9 3 , ▁Spanish ▁authorities ▁in ▁Man ila ▁author ized ▁the ▁dispatch ▁of ▁Francis can ▁mission aries ▁to ▁Japan . ▁The ▁Francis can ▁fri ar ▁Luis ▁S ot elo ▁was ▁involved ▁in ▁the ▁support ▁of ▁the ▁D ila o ▁enc lave ▁between ▁ 1 6 0 0 ▁and ▁ 1 6 0 8 . ▁ ▁In ▁the ▁first ▁half ▁of ▁the ▁ 1 7 th ▁century , ▁inten se ▁official ▁trade ▁took ▁place ▁between ▁the ▁two ▁countries , ▁through ▁the ▁Red ▁se al ▁ships ▁system . ▁Th irty ▁official ▁" Red ▁se al ▁ship " ▁pass ports ▁were ▁issued ▁between ▁Japan ▁and ▁the ▁Philippines ▁between ▁ 1 6 0 4 ▁and ▁ 1 6 1 6 . ▁ ▁The ▁Japanese ▁led ▁an ▁abort ive ▁re bell ion ▁in ▁D ila o ▁against ▁the ▁Spanish ▁Empire ▁in ▁ 1 6 0 6 - 1 6 0 7 , ▁but ▁their ▁numbers ▁rose ▁again ▁until ▁the ▁inter diction ▁of ▁Christian ity ▁by ▁Tok ug awa ▁I ey as u ▁in ▁ 1 6 1 4 , ▁when ▁ 3 0 0 ▁Japanese ▁Christian ▁refuge es ▁under ▁Tak ay ama ▁U kon ▁settled ▁in ▁the ▁Philippines . ▁On ▁ 8 ▁November ▁ 1 6 1 4 , ▁together ▁with ▁ 3 0