▁unusual ▁fa cial ▁features , ▁including ▁prominent , ▁wide - set ▁eyes ▁with ▁outer ▁corners ▁that ▁point ▁down ward ; ▁a ▁short ▁bul b ous ▁nose ▁with ▁a ▁flat ▁nas al ▁bridge ; ▁ears ▁that ▁are ▁rot ated ▁back ward ; ▁and ▁a ▁wid ow ' s ▁peak ▁hair line . ▁ ▁Ind ividual s ▁with ▁Don na i – B arrow ▁synd rome ▁have ▁severe ▁hearing ▁loss ▁caused ▁by ▁ab normal ities ▁of ▁the ▁inner ▁ear ▁( s ensor ine ural ▁hearing ▁loss ). ▁In ▁addition , ▁they ▁often ▁experience ▁vision ▁problems , ▁including ▁extreme ▁ne ars ight ed ness ▁( high ▁my op ia ), ▁det achment ▁or ▁d eter ior ation ▁of ▁the ▁light - sens itive ▁t issue ▁in ▁the ▁back ▁of ▁the ▁eye ▁( the ▁ret ina ), ▁and ▁progress ive ▁vision ▁loss . ▁Some ▁have ▁a ▁gap ▁or ▁split ▁in ▁the ▁colored ▁part ▁of ▁the ▁eye ▁( ir is ▁col ob oma ). ▁▁ ▁In ▁almost ▁all ▁people ▁with ▁Don na i – B arrow ▁synd rome , ▁the ▁t issue ▁connecting ▁the ▁left ▁and ▁right ▁hal ves ▁of ▁the ▁brain ▁( cor pus ▁call os um ) ▁is ▁under develop ed ▁or ▁absent . ▁A ffect ed ▁individuals ▁may ▁also ▁have ▁other ▁struct ural ▁ab normal ities ▁of ▁the ▁brain . ▁They ▁generally ▁have ▁m ild ▁to ▁moder ate ▁intellectual ▁dis ability ▁and ▁development al ▁delay . ▁ ▁People ▁with ▁Don na i – B arrow ▁synd rome ▁may ▁also ▁have ▁a ▁hole ▁in ▁the ▁mus