1 2 ▁p uls es ▁leading ▁to ▁fewer ▁rela ps es ▁than ▁six . ▁Rem ission ▁can ▁be ▁maintained ▁with ▁a ▁less ▁to xic ▁drug , ▁such ▁as ▁az ath iop r ine ▁or ▁m eth ot re x ate . ▁ ▁On ▁December ▁ 1 2 , ▁ 2 0 1 7 , ▁the ▁F DA ▁approved ▁me pol iz um ab , ▁the ▁first ▁drug ▁ther apy ▁specifically ▁indicated ▁for ▁the ▁treatment ▁of ▁e os in oph il ic ▁gran ul om atos is ▁with ▁poly ang i itis . ▁Pat ients ▁taking ▁me pol iz um ab ▁experienced ▁a ▁" sign ific ant ▁improvement " ▁in ▁their ▁sympt oms . ▁ ▁History ▁ ▁E os in oph il ic ▁gran ul om atos is ▁with ▁poly ang i itis ▁was ▁first ▁described ▁by ▁path olog ists ▁Jacob ▁Ch urg ▁( 1 9 1 0 – 2 0 0 5 ) ▁and ▁L otte ▁Stra uss ▁( 1 9 1 3 – 1 9 8 5 ) ▁at ▁Mount ▁S ina i ▁Hospital ▁in ▁New ▁York ▁City ▁in ▁ 1 9 5 1 , ▁using ▁the ▁term ▁" aller g ic ▁gran ul om atos is " ▁to ▁describe ▁it . ▁They ▁reported ▁" f ever ... h yp ere os in oph ilia , ▁sympt oms ▁of ▁card iac ▁failure , ▁ren al ▁damage , ▁and ▁peri pher al ▁ne urop ath y , ▁resulting ▁from ▁v asc ular ▁embar rass ment ▁in ▁various ▁systems ▁of ▁org ans " ▁in