▁the ▁fruit ▁fly ▁can ▁be ▁used ▁as ▁a ▁model ▁of ▁disease , ▁Bon ini ' s ▁labor atory ▁collabor ated ▁with ▁human ▁gen etic ists ▁to ▁examine ▁the ▁effects ▁of ▁express ing ▁normal ▁and ▁mut ant ▁forms ▁of ▁a ▁human ▁ne uro de gener ative ▁poly Q ▁disease ▁protein . ▁F lies ▁that ▁expressed ▁the ▁mut ant ▁form ▁of ▁the ▁protein ▁showed ▁sympt oms ▁and ▁characteristics ▁similar ▁to ▁those ▁seen ▁in ▁human ▁poly Q ▁disease ▁patients ; ▁f lies ▁that ▁expressed ▁the ▁normal ▁protein ▁did ▁not . ▁ ▁Ch aper ones ▁and ▁Poly gl ut am ine ▁Re peat ▁D ise ases ▁Stud ying ▁Poly gl ut am ine ▁repeat ▁dise ases ▁( poly Q ▁dise ases ) ▁in ▁D ros oph ila ▁ne uro de gener ation ▁models , ▁Bon ini ' s ▁research ▁group ▁el uc id ated ▁an ▁important ▁role ▁for ▁mole cular ▁ch aper ones ▁in ▁poly Q ▁dise ases , ▁and ▁subsequently ▁Park inson ' s ▁disease . ▁In ▁those ▁studies , ▁up reg ulation ▁of ▁the ▁ch aper one ▁H sp 7 0 ▁suppress ed ▁ne uro de gener ation , ▁and ▁this ▁finding ▁established ▁ch aper ones ▁as ▁a ▁new ▁th era pe ut ic ▁target ▁for ▁Park inson ' s ▁disease ▁and ▁other ▁ne uro de gener ative ▁dis orders . ▁Bon ini ' s ▁research ▁team ▁demonstrated ▁the ▁ph arm ac olog ic ▁potential ▁of ▁ch aper ones ▁in ▁further ▁D ros oph ila ▁studies ; ▁admin ister ing ▁geld an am yc in