▁medi ated ▁ox id ation ▁of ▁lip ids . ▁In cre ased ▁free ▁radical ▁production ▁may ▁be ▁associated ▁with ▁imp a ired ▁N it ric ▁Ox ide ▁bio av ail ability . ▁ ▁In ▁another ▁study , ▁G PL C ▁or ▁a ▁place bo ▁was ▁provided ▁to ▁resistance ▁trained ▁men ▁for ▁four ▁weeks ▁each , ▁with ▁a ▁two - week ▁was h out ▁period ▁between ▁each ▁four - week ▁period , ▁using ▁a ▁double ▁blind ▁design . ▁At ▁the ▁end ▁of ▁each ▁four - week ▁period , ▁rest ing ▁blood ▁samples ▁were ▁obtained , ▁in ▁addition ▁to ▁blood ▁samples ▁following ▁Is ometric ▁exercise , ▁showing ▁significant ▁increases ▁in ▁pl asma ▁nit rate / nit rite ▁among ▁those ▁who ▁were ▁given ▁G PL C . ▁It ▁is ▁possible ▁that ▁this ▁increase ▁in ▁nit rate / nit rite ▁may ▁have ▁imp lications ▁related ▁to ▁en hanced ▁blood ▁flow ▁during ▁ac ute ▁b outs ▁of ▁exercise . ▁ ▁Ant io x id ant ▁In ▁addition ▁to ▁regular ▁exercise , ▁nut r itional ▁ant io x id ants ▁may ▁combat ▁free ▁radical ▁formation — as ▁has ▁been ▁reported ▁for ▁G PL C . ▁In ▁this ▁study , ▁subjects ▁received ▁or al ▁G PL C ▁at ▁a ▁dos age ▁of ▁either ▁ 1 . 5 ▁or ▁ 4 . 5   gram s ▁per ▁day ▁over ▁the ▁course ▁of ▁an ▁eight - week ▁inter vention ▁period . ▁With ▁both ▁dos ages , ▁the ▁post - inter vention ▁level ▁of ▁mal ond ial de hy de , ▁a ▁marker