▁was ▁used ▁to ▁improve ▁x y lose ▁fer ment ation ▁in ▁Z . ▁mobil is . ▁By ▁adapt ing ▁a ▁stra in ▁in ▁a ▁high ▁concentration ▁of ▁x y lose , ▁significant ▁alter ations ▁of ▁met abol ism ▁occurred . ▁One ▁notice able ▁change ▁was ▁reduced ▁levels ▁of ▁x yl it ol , ▁a ▁by product ▁of ▁x y lose ▁fer ment ation ▁which ▁can ▁in hib it ▁the ▁stra in ’ s ▁x y lose ▁met abol ism . ▁One ▁of ▁the ▁reasons ▁for ▁lower ▁x yl it ol ▁production ▁was ▁mut ation ▁in ▁a ▁put ative ▁gene ▁encoding ▁for ▁an ▁al do - ket o ▁re duct ase ▁that ▁catal y zes ▁the ▁reduction ▁of ▁x y lose ▁to ▁x yl it ol ., ▁ ▁An ▁interesting ▁characteristic ▁of ▁Z . ▁mobil is ▁is ▁that ▁its ▁pl asma ▁memb rane ▁contains ▁hop ano ids , ▁pent acy clic ▁comp ounds ▁similar ▁to ▁e uk ary otic ▁ster ols . ▁This ▁allows ▁it ▁to ▁have ▁an ▁extraordinary ▁toler ance ▁to ▁eth an ol ▁in ▁its ▁environment , ▁around ▁ 1 3 %. ▁ ▁Gen ome ▁ ▁The ▁gen ome ▁of ▁Z . ▁mobil is ▁stra in ▁Z M 4 ▁has ▁been ▁sequ enced ▁and ▁contains ▁ 2 , 0 5 6 , 4 1 6 ▁b p ▁encoding ▁ 1 , 9 9 8 ▁protein ▁coding ▁gen es . ▁This ▁revealed ▁that ▁Z . ▁mobil is ▁can ▁only ▁met abol ise ▁gl uc ose ▁via ▁the ▁Ent ner - D oud or