▁against ▁different ▁hist one ▁modifications , ▁can ▁be ▁used ▁to ▁identify ▁chrom atin ▁states ▁throughout ▁the ▁gen ome . ▁D ifferent ▁modifications ▁have ▁been ▁linked ▁to ▁various ▁states ▁of ▁chrom atin . ▁▁ ▁D N ase - seq ▁( DN ase ▁I ▁hyp ers ens itive ▁sites ▁Se qu encing ) ▁uses ▁the ▁sens itivity ▁of ▁accessible ▁regions ▁in ▁the ▁gen ome ▁to ▁the ▁D N ase ▁I ▁en zym e ▁to ▁map ▁open ▁or ▁accessible ▁regions ▁in ▁the ▁gen ome . ▁▁ ▁FA I RE - seq ▁( Form al de hy de - Ass isted ▁Is olation ▁of ▁Reg ul atory ▁Element s ▁sequ encing ) ▁uses ▁the ▁chemical ▁properties ▁of ▁protein - bound ▁DNA ▁in ▁a ▁two - phase ▁separation ▁method ▁to ▁extract ▁ ▁nucle os ome ▁de ple ted ▁regions ▁from ▁the ▁gen ome . ▁ ▁A TAC - seq ▁( Ass ay ▁for ▁Trans pos able ▁Access ible ▁Ch rom atin ▁sequ encing ) ▁uses ▁the ▁T n 5 ▁trans pos ase ▁to ▁integrate ▁( syn th etic ) ▁trans pos ons ▁into ▁accessible ▁regions ▁of ▁the ▁gen ome ▁consequ entially ▁highlight ing ▁the ▁local isation ▁of ▁nucle os om es ▁and ▁trans cription ▁factors ▁across ▁the ▁gen ome . ▁ ▁DNA ▁foot print ing ▁is ▁a ▁method ▁aim ed ▁at ▁ident ifying ▁protein - bound ▁DNA . ▁It ▁uses ▁label ing ▁and ▁fragment ation ▁couple d ▁to ▁gel ▁elect roph ores is ▁to ▁identify ▁areas ▁of ▁the ▁gen ome ▁that ▁have ▁been ▁bound ▁by ▁prote ins .