▁this ▁effect ▁t ended ▁to ▁be ▁trans ient ▁and ▁usually ▁went ▁away ▁within ▁a ▁matter ▁of ▁minutes ▁after ▁the ▁end ▁of ▁the ▁treatment . ▁In cre ase ▁in ▁blood ▁pressure ▁also ▁occurred ▁in ▁a ▁small ▁but ▁significant ▁percentage ▁of ▁cases , ▁but ▁also ▁was ▁almost ▁invari ably ▁trans ient . ▁ ▁By ▁the ▁late ▁ 1 9 8 0 s ▁is o eth ar ine ▁was ▁largely ▁replaced ▁by ▁or ci pr en al ine ▁( met ap ro ter en ol ), ▁which ▁seemed ▁to ▁have ▁slightly ▁less ▁card iac ▁side ▁effect ▁and ▁last ed ▁a ▁couple ▁of ▁hours ▁longer . ▁Or ci pr en al ine ▁in ▁turn ▁was ▁replaced ▁by ▁sal but am ol ▁( al but er ol ). ▁Some ▁pract ition ers ▁still ▁believe ▁that ▁these ▁later ▁a eros ol ized ▁bron chod il ators ▁never ▁gave ▁quite ▁as ▁quick ▁of ▁relief ▁from ▁ast hm atic ▁short ness ▁of ▁breath ▁as ▁did ▁is o et ar ine . ▁Thus ▁they ▁see ▁a ▁continued ▁special ty ▁role ▁in ▁treatment ▁of ▁severe ▁short ness ▁of ▁breath ▁that ▁does ▁not ▁improve ▁in ▁the ▁first ▁five ▁minutes ▁of ▁sal but am ol ▁treatment . ▁ ▁References ▁ ▁Further ▁reading ▁▁▁▁▁▁ ▁Category : P hen yle than ol am ines ▁Category : B eta - adr ener g ic ▁ag on ists ▁Category : C ate ch ol am ines ▁Category : Is op rop yl ▁comp ounds <0x0A> </s> ▁The ▁Pa ag ▁is ▁a ▁he address ▁in ▁the ▁M ith ila ▁region