▁are ▁involved ▁primarily ▁with ▁the ▁R NA ▁inter ference ▁( R NA i ) ▁path way . ▁ ▁mi R - 6 1 8 ▁in ▁o estro gen ▁treatment ▁Dec re ased ▁levels ▁of ▁mi R - 6 1 8 ▁have ▁been ▁observed ▁in ▁est rad i ol ( E 2 )- st im ulated ▁M CF - 7 ▁breast ▁cancer ▁cells ▁following ▁h orm one ▁dep riv ation . ▁Int rac ell ular ▁mi R - 6 1 8 ▁levels ▁can ▁be ▁reg ulated ▁by ▁E 2 ▁via ▁the ▁ER 2 ▁re ceptor . ▁This ▁points ▁towards ▁a ▁possible ▁of ▁this ▁mi R NA , ▁amongst ▁others , ▁in ▁mod ulating ▁the ▁final ▁gene ▁responses ▁to ▁the ▁o estro gen ▁family ▁of ▁h orm ones ▁in ▁breast ▁cancer ▁cells . ▁ ▁Micro gravity ▁effects ▁in ▁l ym ph ob las to id ▁cells ▁Alter ed ▁expression ▁of ▁mi R - 6 1 8 ▁has ▁been ▁seen ▁in ▁the ▁human ▁l ym ph ob las to id ▁T K 6 ▁cell ▁line , ▁with ▁down reg ulation ▁following ▁stress - related ▁stim ulated ▁micro gravity ▁in ▁T K 6 ▁cells . ▁This ▁further ▁influ ences ▁several ▁gen es ▁involved ▁in ▁reg ulation ▁of ▁the ▁N F - κ B - related ▁path way ▁network . ▁ ▁See ▁also ▁▁ ▁Micro R NA ▁ ▁References ▁ ▁Further ▁reading ▁ ▁External ▁links ▁▁▁▁ ▁Category : M icro R NA ▁Category : M icro R NA ▁prec ursor ▁families <0x0A> </s> ▁The ▁M aus ole um