▁the ▁subm and ib ular ▁g land ▁pe pt ide - T . ▁ ▁S GP - T ▁was ▁demonstrated ▁to ▁have ▁bi ological ▁activity ▁and ▁therm or eg ul atory ▁properties ▁related ▁to ▁end ot ox in ▁expos ure . ▁ ▁S GP - T , ▁an ▁isol ate ▁of ▁the ▁subm and ib ular ▁g land , ▁demonstrated ▁its ▁imm un or eg ul atory ▁properties ▁and ▁potential ▁role ▁in ▁mod ulating ▁the ▁cer v ical ▁sympath etic ▁tr unk - sub m and ib ular ▁g land ▁( C ST - SM G ) ▁axis , ▁and ▁subsequently ▁was ▁shown ▁to ▁play ▁an ▁important ▁role ▁in ▁the ▁control ▁of ▁infl amm ation . ▁ ▁Mechan isms ▁or ▁Im m uno Ph arm ac ology ▁It ▁is ▁now ▁well ▁accepted ▁that ▁the ▁imm une , ▁nerv ous ▁and ▁end ocr ine ▁systems ▁communicate ▁and ▁interact ▁to ▁control ▁and ▁mod ulate ▁infl amm ation ▁and ▁t issue ▁repair . ▁One ▁of ▁the ▁ne uro end ocr ine ▁path ways , ▁when ▁activ ated , ▁results ▁in ▁the ▁release ▁of ▁imm une ▁reg ulating ▁pe pt ides ▁from ▁the ▁subm and ib ular ▁g land ▁upon ▁neur onal ▁stim ulation ▁from ▁sympath etic ▁n erves . ▁ ▁This ▁path way ▁or ▁communication ▁is ▁referred ▁to ▁as ▁the ▁cer v ical ▁sympath etic ▁tr unk - sub m and ib ular ▁g land ▁( C ST - SM G ) ▁axis , ▁a ▁regul atory ▁system ▁that ▁plays ▁a ▁role ▁in ▁the ▁system ic