▁mel an og aster ▁can ▁express ▁the ▁alco hol ▁de h ydro gen ase ▁( AD H ) ▁mut ation , ▁thereby ▁prevent ing ▁the ▁break down ▁of ▁to xic ▁levels ▁of ▁alco h ols ▁into ▁al de hy des ▁and ▁k et ones . ▁While ▁eth an ol ▁produced ▁by ▁decay ing ▁fruit ▁is ▁a ▁natural ▁food ▁source ▁and ▁location ▁for ▁ov ip os it ▁for ▁D ros oph ila ▁at ▁low ▁concentr ations ▁( < 4 % ), ▁high ▁concentr ations ▁of ▁eth an ol ▁can ▁indu ce ▁ox id ative ▁stress ▁and ▁alco hol ▁into xic ation . ▁D ros oph ila ’ s ▁fit ness ▁is ▁elev ated ▁by ▁cons uming ▁the ▁low ▁concentration ▁of ▁eth an ol . ▁Initial ▁expos ure ▁to ▁eth an ol ▁causes ▁hyper activity , ▁followed ▁by ▁in co ord ination ▁and ▁sed ation . ▁Further ▁research ▁has ▁shown ▁that ▁the ▁ant io x id ant ▁alpha - ket og l ut ar ate ▁may ▁be ▁benef icial ▁in ▁reducing ▁the ▁ox id ative ▁stress ▁produced ▁by ▁alco hol ▁consumption . ▁A ▁ 2 0 1 6 ▁study ▁concluded ▁that ▁food ▁supp lement ation ▁with ▁ 1 0 - m M ▁alpha - ket og l ut ar ate ▁decre ased ▁D ros oph ila ▁alco hol ▁sens itivity ▁over ▁time . ▁For ▁the ▁gene ▁that ▁codes ▁for ▁AD H , ▁there ▁are ▁ 1 9 4 ▁known ▁classic ▁and ▁insert ion ▁alle les . ▁Two ▁alle les ▁that ▁are ▁commonly ▁used ▁for ▁experiment