▁increasing ▁def ic it ▁to ▁the ▁don or . ▁ ▁Some ▁evidence ▁suggests ▁that ▁local ▁delivery ▁of ▁sol ub le ▁ne uro t roph ic ▁factors ▁at ▁the ▁site ▁of ▁aut olog ous ▁n erve ▁gra ft ing ▁may ▁enh ance ▁ax on ▁reg ener ation ▁within ▁the ▁gra ft ▁and ▁help ▁exped ite ▁functional ▁recovery ▁of ▁a ▁par al yz ed ▁target . ▁Other ▁evidence ▁suggests ▁that ▁gene - ther apy ▁induced ▁expression ▁of ▁ne uro t roph ic ▁factors ▁within ▁the ▁target ▁mus cle ▁itself ▁can ▁also ▁help ▁enh ance ▁ax on ▁reg ener ation . ▁Acc eler ating ▁neur or eg ener ation ▁and ▁the ▁re inner v ation ▁of ▁a ▁d ener v ated ▁target ▁is ▁crit ically ▁important ▁in ▁order ▁to ▁reduce ▁the ▁possibility ▁of ▁permanent ▁par al ysis ▁due ▁to ▁mus cular ▁at ro phy . ▁ ▁Al log raft s ▁and ▁x en og raft s ▁ ▁Vari ations ▁on ▁the ▁n erve ▁aut og raft ▁include ▁the ▁al log raft ▁and ▁the ▁x en og raft . ▁In ▁al log raft s , ▁the ▁t issue ▁for ▁the ▁gra ft ▁is ▁taken ▁from ▁another ▁person , ▁the ▁don or , ▁and ▁impl anted ▁in ▁the ▁recip ient . ▁X en og raft s ▁involve ▁taking ▁don or ▁t issue ▁from ▁another ▁species . ▁Al log raft s ▁and ▁x en og raft s ▁have ▁the ▁same ▁dis adv antages ▁as ▁aut og raft s , ▁but ▁in ▁addition , ▁t issue ▁re jection ▁from ▁imm