▁h yst ere ct omy ▁and ▁sal ping o - o oph ore ct omy ▁( rem oval ▁of ▁the ▁u ter us , ▁Fal lop ian ▁tub es , ▁and ▁o var ies ▁to ▁prevent ▁cancer ▁from ▁developing ) ▁can ▁be ▁performed ▁before ▁o var ian ▁or ▁end omet rial ▁cancer ▁develop s . ▁ ▁Tre at ment ▁S urg ery ▁remains ▁the ▁front - line ▁ther apy ▁for ▁H NP CC . ▁There ▁is ▁an ▁on going ▁controvers y ▁over ▁the ▁benefit ▁of ▁ 5 - flu or ou rac il - based ▁adj uv ant ▁ther ap ies ▁for ▁H NP CC - related ▁col ore ct al ▁tum ours , ▁particularly ▁those ▁in ▁stages ▁I ▁and ▁II . ▁ ▁Anti - PD - 1 ▁ant ib ody ▁ther apy ▁can ▁be ▁effective . ▁ ▁Ep ide mi ology ▁In ▁the ▁United ▁States , ▁about ▁ 1 6 0 , 0 0 0 ▁new ▁cases ▁of ▁col ore ct al ▁cancer ▁are ▁diagn osed ▁each ▁year . ▁Her edit ary ▁non poly pos is ▁col ore ct al ▁cancer ▁is ▁responsible ▁for ▁approximately ▁ 2 ▁percent ▁to ▁ 7 ▁percent ▁of ▁all ▁diagn osed ▁cases ▁of ▁col ore ct al ▁cancer . ▁The ▁average ▁age ▁of ▁diagn osis ▁of ▁cancer ▁in ▁patients ▁with ▁this ▁synd rome ▁is ▁ 4 4 ▁years ▁old , ▁as ▁compared ▁to ▁ 6 4 ▁years ▁old ▁in ▁people ▁without ▁the ▁synd rome . ▁ ▁Term in ology ▁Henry ▁T . ▁Lyn ch , ▁Professor ▁of