▁events ▁such ▁as ▁in fe ctions ▁or ▁ant if ibr in ol yt ic ▁ther apy . ▁Hist ology ▁shows ▁am orph ous ▁sub ep ith el ial ▁depos its ▁of ▁e os in oph il ic ▁material ▁consisting ▁pre domin antly ▁of ▁f ibr in . ▁ ▁Di agn osis ▁ ▁Tre at ment ▁L igne ous ▁conj unct iv itis ▁may ▁be ▁managed ▁by ▁top ical ▁treat ments ▁of ▁pl as min ogen , ▁top ical ▁and ▁sub con j unct ival ▁fresh ▁fro zen ▁pl asma , ▁and ▁f ibr in ol yt ic ▁ther apy . ▁ ▁References ▁ ▁External ▁links ▁▁ ▁Category : Dis orders ▁of ▁conj unct iva ▁Category : Infl amm ations ▁Category : Ig G 4 - related ▁disease <0x0A> </s> ▁Ep ide mi ology ▁of ▁period ont al ▁disease ▁is ▁the ▁study ▁of ▁patterns , ▁causes , ▁and ▁effects ▁of ▁period ont al ▁dise ases . ▁Period ont al ▁disease ▁is ▁a ▁disease ▁affect ing ▁the ▁t issue ▁surrounding ▁the ▁teeth . ▁This ▁causes ▁the ▁g ums ▁and ▁the ▁teeth ▁to ▁separate ▁making ▁spaces ▁that ▁become ▁inf ected . ▁The ▁imm une ▁system ▁tries ▁to ▁fight ▁the ▁to x ins ▁breaking ▁down ▁the ▁b one ▁and ▁t issue ▁connecting ▁to ▁the ▁teeth ▁to ▁the ▁g ums . ▁The ▁teeth ▁will ▁have ▁to ▁be ▁removed . ▁This ▁is ▁an ▁advance ▁stage ▁of ▁g um ▁disease ▁that ▁has ▁multiple ▁definitions . ▁Ad ult ▁period ont itis ▁affect s ▁less ▁than ▁ 1 0 ▁to ▁ 1