▁S . ▁py ogen es ▁in fection ▁is ▁more ▁frequently ▁found ▁in ▁men ▁than ▁women , ▁with ▁highest ▁rates ▁in ▁the ▁elder ly , ▁followed ▁by ▁inf ants . ▁In ▁people ▁with ▁risk ▁factors ▁such ▁as ▁heart ▁disease , ▁di ab etes , ▁m align ancy , ▁bl unt ▁tra uma , ▁surg ical ▁inc ision , ▁virus ▁resp ir atory ▁in fection , ▁including ▁influen za , ▁S . ▁py ogen es ▁in fection ▁happens ▁in ▁ 1 7 ▁to ▁ 2 5 % ▁of ▁all ▁cases . ▁G AS ▁secondary ▁in fection ▁usually ▁happens ▁within ▁one ▁week ▁of ▁the ▁diagn osis ▁of ▁influen za ▁in fection . ▁In ▁ 1 4 ▁to ▁ 1 6 % ▁of ▁child hood ▁S . ▁py ogen es ▁in fe ctions , ▁there ▁is ▁a ▁prior ▁ch icken po x ▁in fection . ▁Such ▁S . ▁py ogen es ▁in fection ▁in ▁children ▁usually ▁manifest s ▁as ▁severe ▁soft ▁t issue ▁in fection ▁with ▁on set ▁ 4 ▁to ▁ 1 2 ▁days ▁from ▁the ▁ch icken po x ▁diagn osis . ▁There ▁is ▁also ▁ 4 0 ▁to ▁ 6 0 ▁times ▁increase ▁in ▁risk ▁of ▁S . ▁py ogen es ▁in fection ▁within ▁the ▁first ▁two ▁weeks ▁of ▁ch icken po x ▁in fection ▁in ▁children . ▁However , ▁ 2 0 ▁to ▁ 3 0 % ▁of ▁S . ▁py ogen es ▁in fection ▁does ▁occur ▁in ▁adult s ▁with ▁no ▁ident ifiable ▁risk ▁factors . ▁The ▁inc idence ▁is ▁higher ▁in