oms ; ▁in ▁other ▁cases , ▁anx iety ▁develop s ▁after ▁on set ▁of ▁the ▁dis order , ▁which ▁suggests ▁that ▁a ▁gut - dri ven ▁brain ▁dis order ▁may ▁be ▁a ▁possible ▁cause . ▁Although ▁ben ign , ▁these ▁sympt oms ▁may ▁be ▁chron ic ▁and ▁difficult ▁to ▁treat . ▁ ▁Whe at ▁and ▁di et ary ▁f ats ▁can ▁lead ▁to ▁d ys pe ps ia ▁and ▁their ▁reduction ▁or ▁withdraw al ▁may ▁improve ▁sympt oms . ▁ ▁Liver ▁and ▁pan cre as ▁dise ases ▁ ▁These ▁include ▁ch ole l ith ias is , ▁chron ic ▁pan cre at itis ▁and ▁pan cre atic ▁cancer . ▁ ▁Food ▁or ▁drug ▁int ol er ance ▁ ▁Ac ute , ▁self - limited ▁d ys pe ps ia ▁may ▁be ▁caused ▁by ▁over e ating , ▁e ating ▁too ▁quickly , ▁e ating ▁high - f at ▁food s , ▁e ating ▁during ▁stress ful ▁situations , ▁or ▁drink ing ▁too ▁much ▁alco hol ▁or ▁coffee . ▁Many ▁medic ations ▁cause ▁d ys pe ps ia , ▁including ▁asp ir in , ▁non st ero idal ▁anti - infl am mat ory ▁dru gs ▁( NS A ID s ), ▁ant ib iot ics ▁( met ron id az ole , ▁mac rol ides ), ▁di ab etes ▁dru gs ▁( met form in , ▁Al pha - gl uc os id ase ▁in hib itor , ▁am y lin ▁anal ogs , ▁GL P - 1 ▁re ceptor ▁ant agon ists