▁kin ase ▁path way . ▁A ▁def ic iency ▁in ▁any ▁of ▁these ▁path ways ▁would ▁lead ▁to ▁the ▁in ability ▁to ▁develop ▁a ▁neur on . ▁ ▁After ▁forming ▁one ▁ax on , ▁the ▁neur on ▁must ▁prevent ▁all ▁other ▁neur ites ▁from ▁becoming ▁ax ons ▁as ▁well . ▁This ▁is ▁known ▁as ▁global ▁in hib ition . ▁It ▁has ▁been ▁suggested ▁that ▁global ▁in hib ition ▁is ▁achieved ▁by ▁a ▁long - range ▁negative ▁feedback ▁signal ▁released ▁from ▁the ▁developed ▁ax on ▁and ▁taken ▁up ▁by ▁the ▁other ▁neur ite . ▁However , ▁no ▁long ▁range ▁signal ing ▁mole c ule ▁has ▁been ▁discovered . ▁Alternatively , ▁it ▁has ▁been ▁suggested ▁that ▁the ▁bu il dup ▁of ▁ax onal ▁growth ▁factors ▁in ▁the ▁neur ite ▁dest ined ▁to ▁become ▁the ▁ax on ▁means ▁there ▁is ▁a ▁de ple tion ▁of ▁ax onal ▁growth ▁factors ▁by ▁default , ▁as ▁they ▁must ▁comp ete ▁for ▁the ▁same ▁prote ins . ▁This ▁causes ▁the ▁other ▁neur ites ▁to ▁develop ▁into ▁d end rit es ▁as ▁they ▁lack ▁sufficient ▁concentr ations ▁of ▁ax onal ▁growth ▁factors ▁to ▁become ▁ax ons . ▁This ▁would ▁allow ▁for ▁a ▁mechanism ▁of ▁global ▁in hib ition ▁without ▁the ▁need ▁for ▁a ▁long ▁range ▁signal ing ▁mole c ule . ▁ ▁See ▁also ▁▁ ▁Lew y ▁neur ites ▁ ▁Un ip olar ▁neur on ▁ ▁References ▁ ▁External ▁links ▁ ▁E ▁Me ij ering ' s ▁article ▁on ▁the ▁state ▁of ▁neur ite ▁detection ▁ ▁Ne ur on J ▁neur