id az ole ▁groups ▁on ▁T C DI ▁can ▁be ▁easily ▁disp la ced , ▁allowing ▁it ▁to ▁act ▁as ▁a ▁sa fer ▁alternative ▁to ▁th i oph os g ene . ▁This ▁behaviour ▁has ▁been ▁used ▁in ▁the ▁Core y – W inter ▁o le fin ▁synth esis . ▁It ▁may ▁also ▁replace ▁carbon oth io yl ▁species ▁( RC ( S ) Cl ) ▁in ▁the ▁Bart on – Mc Com bie ▁de ox y gen ation . ▁Other ▁uses ▁include ▁the ▁synth esis ▁of ▁th io am ides ▁and ▁th i oc ar b am ates . ▁Like ▁the ▁analog ous ▁C DI , ▁it ▁may ▁be ▁used ▁for ▁pe pt ide ▁coupling . ▁ ▁References ▁ ▁Category : Th i ou reas ▁Category : Im id az oles ▁Category : Pe pt ide ▁coupling ▁re ag ents <0x0A> </s> ▁C ash ▁return ▁on ▁capital ▁inv ested ▁( C RO CI ) ▁is ▁an ▁advanced ▁measure ▁of ▁corpor ate ▁profit ability , ▁originally ▁developed ▁by ▁Deutsche ▁Bank ' s ▁equ ity ▁research ▁department ▁in ▁ 1 9 9 6 ▁( it ▁now ▁s its ▁within ▁D WS ▁Group ). This ▁measure ▁comp ares ▁a ▁post - tax , ▁pre - inter est ▁c ash ▁flow ▁to ▁the ▁gross ▁level ▁of ▁capital ▁inv ested ▁and ▁is ▁a ▁useful ▁measure ▁of ▁a ▁company ’ s ▁ability ▁to ▁generate ▁c ash ▁returns ▁on ▁its ▁invest ments . ▁ ▁In ▁principle , ▁this ▁ratio ▁is ▁similar ▁to ▁the ▁RO E ▁ratio , ▁but ▁C