ros ine - based ▁sorting ▁signals ▁within ▁the ▁cy top las mic ▁domains ▁of ▁transm emb rane ▁cargo ▁prote ins . ▁One ▁function ▁of ▁cl ath rin ▁and ▁AP 2 ▁complex - medi ated ▁end oc yt osis ▁is ▁to ▁reg ulate ▁the ▁number ▁of ▁G AB A ( A ) ▁re cept ors ▁available ▁at ▁the ▁cell ▁surface ▁. ▁ ▁See ▁also ▁List ▁of ▁adapt ins ▁ ▁References ▁ ▁External ▁links ▁▁▁▁▁▁▁ ▁Category : Per i pher al ▁memb rane ▁prote ins ▁Category : Pro te in ▁families <0x0A> </s> ▁Kinder le ▁C ave ▁( , ▁) ▁is ▁the ▁second ▁longest ▁cave ▁in ▁the ▁Southern ▁Ur als . ▁It ▁is ▁located ▁on ▁the ▁territory ▁of ▁the ▁Z il im ▁Nature ▁Park , ▁ 5 ▁km ▁from ▁the ▁village ▁of ▁T ash ast i ▁on ▁the ▁right ▁bank ▁of ▁the ▁Kinder le ▁River ▁in ▁Bash k ort ost an , ▁Russia . ▁The ▁cave ▁was ▁formed ▁in ▁the ▁Dev onian ▁period ▁and ▁consists ▁of ▁ 4 ▁horizontal ▁flo ors . ▁▁ ▁The ▁entrance ▁to ▁the ▁cave ▁is ▁located ▁at ▁an ▁alt itude ▁of ▁ 9 4 ▁m ▁and ▁is ▁connected ▁to ▁an ▁incl ined ▁tunnel . ▁In ▁the ▁tunnel ▁is ▁a ▁gla cier ▁meas uring ▁ 7 2 0 ▁square ▁m ▁and ▁a ▁thick ness ▁of ▁ 8 ▁m . ▁Vari ous ▁stal ag mit es ▁grow ▁on ▁the ▁gla cier . ▁The ▁length ▁of ▁the ▁cave ▁is ▁ 8 1 3 0 ▁m , ▁including ▁ 2 3 0 ▁m ▁under ▁water