▁I ▁tri als ▁of ▁sel ic ic lib ▁for ▁NS CLC ▁were ▁" n ause a , ▁vom iting , ▁trans ient ▁elev ations ▁in ▁ser um ▁cre atin ine ▁and ▁li ver ▁function ▁parameters ▁and ▁trans ient ▁hyp ok alem ia ". ▁ ▁Sel ic ic lib ▁is ▁also ▁in ▁clin ical ▁tri als ▁for ▁B - cell ▁l ym ph omas , ▁including ▁multiple ▁my el oma . ▁Sel ic ic lib ▁has ▁been ▁shown ▁to ▁in hib it ▁R NA ▁polym er ase ▁II - dependent ▁trans cription ▁and ▁down - reg ulation ▁of ▁the ▁protein ▁M CL 1 . ▁ ▁Sel ic ic lib ▁is ▁also ▁a ▁possible ▁ant iv iral ▁agent . ▁It ▁causes ▁the ▁death ▁of ▁cells ▁inf ected ▁with ▁H IV ▁and ▁prevent ing ▁the ▁rep lication ▁of ▁her pes ▁simple x ▁virus . ▁ ▁Sel ic ic lib ▁has ▁been ▁shown ▁in ▁vit ro ▁to ▁indu ce ▁apo pt osis ▁in ▁neut roph il ▁gran ul ocy tes . ▁If ▁this ▁mechanism ▁turns ▁out ▁to ▁be ▁safe , ▁reliable ▁and ▁efficient ▁in ▁v ivo , ▁the ▁drug ▁could ▁improve ▁treatment ▁of ▁chron ic ▁infl amm ation ▁dise ases ▁such ▁as ▁c yst ic ▁fib ros is ▁and ▁ar th rit is . ▁These ▁are ▁usually ▁treated ▁with ▁gl uc oc ort ico ids ▁which ▁often ▁have ▁serious ▁side ▁effects . ▁ ▁Sel ic ic lib ▁has ▁been ▁shown ▁to ▁cause ▁par th ogen etic ▁egg ▁activation . ▁However ▁it ▁does ▁create ▁ab normal ▁second ▁polar