▁chap el ▁in ▁the ▁church ▁of ▁Santa ▁Maria ▁del ▁Car mine ▁in ▁P isa . ▁The ▁work ▁was ▁dis m ant led ▁and ▁dispers ed ▁in ▁the ▁ 1 8 th ▁century , ▁and ▁only ▁eleven ▁of ▁about ▁twenty ▁original ▁pan els ▁have ▁been ▁redis cover ed ▁in ▁various ▁collections ▁around ▁the ▁world . ▁The ▁central ▁panel ▁of ▁the ▁alt arp ie ce ▁( The ▁Madonna ▁and ▁Child ) ▁is ▁now ▁in ▁the ▁National ▁Gallery , ▁London . ▁Although ▁it ▁is ▁very ▁dam aged , ▁the ▁work ▁features ▁a ▁sculpt ural ▁and ▁human ▁Madonna ▁as ▁well ▁as ▁a ▁convin cing ▁pers pect ival ▁dep iction ▁of ▁her ▁throne . ▁Mas ac cio ▁probably ▁worked ▁on ▁it ▁entirely ▁in ▁P isa , ▁sh utt ling ▁back ▁and ▁forth ▁to ▁Florence , ▁where ▁he ▁was ▁still ▁working ▁on ▁the ▁Bran c acci ▁Chap el . ▁In ▁these ▁years , ▁Don at ello ▁was ▁also ▁working ▁in ▁P isa ▁at ▁a ▁monument ▁for ▁Card inal ▁R inal do ▁Bran c acci , ▁to ▁be ▁sent ▁to ▁Nap les . ▁It ▁is ▁suggested ▁that ▁Mas ac cio ' s ▁first ▁vent ures ▁in ▁pl astic ity ▁and ▁perspective ▁were ▁based ▁on ▁Don at ello ' s ▁sculpt ure , ▁before ▁he ▁could ▁study ▁Brun ell esch i ' s ▁more ▁scientific ▁approach ▁to ▁perspective . ▁ ▁Holy ▁Tr inity ▁Ar ound ▁ 1 4 2 7 ▁Mas ac cio ▁won ▁a ▁pr estig ious ▁commission ▁to ▁produce ▁a ▁Holy ▁Tr inity ▁for ▁the ▁Domin ican ▁church ▁of