▁Ice house ▁B ottom ▁in ▁the ▁ 1 9 7 0 s ▁show ▁evidence ▁of ▁interaction ▁with ▁the ▁Hope well ▁people ▁of ▁what ▁is ▁now ▁Ohio . ▁ ▁Mississ ipp ian ▁period ▁( c . ▁ 1 0 0 0 - 1 5 0 0 ▁A . D .) ▁sites ▁in ▁the ▁Little ▁Tennessee ▁Valley ▁include ▁the ▁To qua ▁site ▁( at ▁the ▁river ' s ▁confl u ence ▁with ▁To qua ▁Creek ), ▁Tom ot ley ▁( adj acent ▁to ▁To qua ), ▁Cit ico ▁( at ▁the ▁river ' s ▁Cit ico ▁Creek ▁confl u ence ), ▁and ▁B uss ell ▁Island ▁( at ▁the ▁mouth ▁of ▁the ▁river ). ▁ ▁To qua ' s ▁Mississ ipp ian ▁inhabitants ▁constructed ▁a ▁ ▁platform ▁m ound ▁over looking ▁a ▁central ▁pla za . ▁ ▁By ▁ 1 4 0 0 , ▁the ▁village ▁covered ▁ ▁surrounded ▁by ▁a ▁cl ay - cover ed ▁pal is ade . ▁ ▁Several ▁Ch ero kee ▁Middle ▁towns , ▁including ▁Nik w asi , ▁J ore , ▁and ▁Cow ee ▁were ▁located ▁along ▁the ▁river ' s ▁North ▁Carolina ▁section . ▁ ▁The ▁river ▁was ▁also ▁home ▁to ▁most ▁of ▁the ▁major ▁Over hill ▁Ch ero kee ▁towns , ▁the ▁most ▁prominent ▁of ▁which ▁included ▁Ch ota , ▁Tan asi , ▁To qua , ▁Tom ot ley , ▁M ial o qu o ▁( near ▁Rose ▁Island ), ▁Ch il how ee ▁( at ▁the ▁river ' s ▁Abr ams ▁Creek ▁confl u ence ), ▁T