1 2 4 ▁during ▁neur onal ▁different iation . ▁ ▁Target s ▁of ▁mi R - 1 2 4 ▁ ▁Vis van athan ▁et ▁al .. ▁showed ▁that ▁mi R - 1 2 4 ▁targets ▁the ▁m R NA ▁of ▁the ▁anti - ne ural ▁function ▁protein ▁S CP 1 ▁( small ▁C - term inal ▁domain ▁ph osph at ase ▁ 1 ). ▁ ▁Make ye v ▁et ▁al . ▁showed ▁that ▁mi R - 1 2 4 ▁directly ▁targets ▁P TB P 1 ▁( PT B / hn R NP ▁I ) ▁m R NA , ▁which ▁enc odes ▁a ▁global ▁repr essor ▁of ▁alternative ▁pre - m R NA ▁sp lic ing ▁in ▁non - neur onal ▁cells . ▁Ar rant ▁et ▁al . ▁wrote ▁that ▁mi R - 1 2 4 ▁changes ▁gl ut am ate ▁re ceptor ▁composition ▁in ▁the ▁pre front al ▁cor tex ▁and ▁can ▁decrease ▁social ▁d ys function ▁in ▁front ot empor al ▁de ment ia . ▁ ▁C lin ical ▁medicine ▁Pres ence ▁of ▁the ▁G ▁alle le , ▁compared ▁to ▁the ▁C ▁alle le , ▁in ▁SN P ▁rs 5 3 1 5 6 4 ▁in ▁pri - mi R - 1 2 4 - 1 , ▁measured ▁by ▁PC R - R FL P ▁in ▁le uk ocy te ▁DNA , ▁is ▁linked ▁to ▁a ▁reduced ▁risk ▁of ▁g astr ic ▁cancer ▁( e . g . ▁G G ▁v ▁CC ▁OR ▁ 0 . 3 4 ▁ 9 5 %