: ▁hence ▁the ▁name . ▁ ▁In ▁humans ▁AD M ▁is ▁encoded ▁by ▁the ▁AD M ▁gene . ▁AD M ▁is ▁a ▁pe pt ide ▁expressed ▁by ▁all ▁t issues , ▁and ▁found ▁in ▁the ▁circul ation . ▁A ▁similar ▁pe pt ide ▁named ▁ad re omed ull in 2 ▁was ▁reported ▁in ▁r ats ▁in ▁ 2 0 0 4 ▁which ▁exhib its ▁a ▁similar ▁function . ▁ ▁Function ▁ ▁Ad ren omed ull in ▁may ▁function ▁as ▁a ▁h orm one ▁in ▁the ▁circul ation ▁control ▁because ▁it ▁is ▁found ▁in ▁blood ▁in ▁a ▁considerable ▁concentration . ▁It ▁was ▁initially ▁identified ▁as ▁a ▁vas od il ator , ▁and ▁some ▁argued ▁that ▁it ▁is ▁the ▁most ▁pot ent ▁end ogen ous ▁vas od il atory ▁pe pt ide ▁found ▁in ▁the ▁body . ▁ ▁D iffer ences ▁in ▁opinion ▁regarding ▁the ▁ability ▁of ▁AM ▁to ▁relax ▁v asc ular ▁tone ▁may ▁arise ▁from ▁the ▁differences ▁in ▁the ▁model ▁system ▁used . ▁ ▁Other ▁effects ▁of ▁AM ▁include ▁stim ulating ▁the ▁growth ▁of ▁new ▁blood ▁vessels ▁( ang i ogen esis ) ▁and ▁increasing ▁the ▁toler ance ▁of ▁cells ▁to ▁ox id ative ▁stress ▁and ▁hy po xic ▁injury . ▁ ▁Ad ren omed ull in ▁is ▁seen ▁as ▁a ▁positive ▁influence ▁in ▁dise ases ▁such ▁as ▁hy pert ension , ▁my oc ard ial ▁inf ar ction , ▁chron ic ▁ob struct ive ▁pul mon ary ▁disease ▁and ▁other ▁card i ov asc ular ▁dise ases , ▁whereas ▁it ▁can ▁be