, ▁however ▁alpha - 7 B ▁integr in ▁is ▁expressed ▁more ▁lo os ely ▁in ▁stri ated ▁mus cle ▁as ▁well ▁as ▁the ▁vas cul ature . ▁ ▁Function ▁▁ ▁The ▁function ▁of ▁alpha - 7 ▁integr in , ▁as ▁is ▁the ▁case ▁for ▁most ▁integr ins ▁is ▁to ▁medi ate ▁cell ▁memb rane ▁interactions ▁with ▁ext rac ell ular ▁matrix . ▁ ▁The ▁alpha - 7 / beta - 1 ▁integr in ▁complex ▁clearly ▁plays ▁a ▁role ▁in ▁the ▁development ▁of ▁stri ated ▁mus cle ▁and ▁smooth ▁mus cle . ▁Al pha - 7 / beta - 1 ▁integr in ▁prom otes ▁the ▁ad hes ion ▁and ▁mot ility ▁of ▁my ob last s , ▁and ▁is ▁likely ▁important ▁in ▁the ▁rec ruit ment ▁of ▁my ogen ic ▁prec urs ors ▁during ▁mus cle ▁different iation . ▁It ▁was ▁shown ▁however ▁that ▁beta - 1 D ▁integr in ▁appears ▁at ▁emb ry onic ▁day ▁ 1 1 ▁and ▁alpha - 7 ▁integr in ▁does ▁not ▁appear ▁until ▁emb ry onic ▁day ▁ 1 7 ; ▁thus , ▁beta - 1 D ▁associ ates ▁with ▁alternate ▁alpha ▁sub un its ▁( alpha - 5 , ▁alpha - 6 A ) ▁prior ▁to ▁alpha - 7 . ▁In ▁human ▁ske let al ▁mus cle , ▁alpha - 7 ▁integr in ▁is ▁also ▁development ally ▁reg ulated , ▁being ▁first ▁detected ▁at ▁age ▁ 2 . ▁ ▁In ▁adult ▁stri ated ▁mus cle ▁cells , ▁alpha - 7 ▁integr in ▁( complex ed ▁to ▁beta