▁en zym e ▁will ▁hydro ly se ▁the ▁ β - la ct am ▁ring ▁of ▁the ▁ant ib i otic , ▁rendering ▁the ▁ant ib i otic ▁in effect ive . ▁( An ▁example ▁of ▁such ▁an ▁en zym e ▁is ▁New ▁Del hi ▁metal lo - beta - la ct am ase ▁ 1 , ▁discovered ▁in ▁ 2 0 0 9 .) ▁The ▁gen es ▁encoding ▁these ▁en zym es ▁may ▁be ▁inher ently ▁present ▁on ▁the ▁b acter ial ▁chrom os ome ▁or ▁may ▁be ▁acquired ▁via ▁pl as mid ▁transfer ▁( pl as mid - medi ated ▁resistance ), ▁and ▁ β - la ct am ase ▁gene ▁expression ▁may ▁be ▁induced ▁by ▁expos ure ▁to ▁ β - la ct ams . ▁ ▁The ▁production ▁of ▁a ▁ β - la ct am ase ▁by ▁a ▁b acter ium ▁does ▁not ▁necessarily ▁rule ▁out ▁all ▁treatment ▁options ▁with ▁ β - la ct am ▁ant ib iot ics . ▁ ▁In ▁some ▁instances , ▁ β - la ct am ▁ant ib iot ics ▁may ▁be ▁co - admin ister ed ▁with ▁a ▁ β - la ct am ase ▁in hib itor . ▁For ▁example , ▁Aug ment in ▁( F GP ) ▁is ▁made ▁of ▁am ox ic ill in ▁( a ▁ β - la ct am ▁ant ib i otic ) ▁and ▁cla v ul an ic ▁acid ▁( a ▁ β - la ct am ase ▁in hib itor ). ▁The ▁cla