▁impl anted ▁som atic ▁cell ▁nuc lei ▁into ▁cells ▁with ▁pl ur ip ot ent ▁states . ▁When ▁the ▁ov um ' s ▁nucle us ▁is ▁removed , ▁the ▁cell ▁los es ▁its ▁gen etic ▁information . ▁This ▁has ▁been ▁bl amed ▁for ▁why ▁en uc le ated ▁eggs ▁are ▁ham per ed ▁in ▁their ▁re programming ▁ability . ▁It ▁is ▁the or ized ▁the ▁critical ▁emb ry onic ▁gen es ▁are ▁phys ically ▁linked ▁to ▁o ocy te ▁chrom os om es , ▁en uc le ation ▁neg atively ▁affect s ▁these ▁factors . ▁Another ▁possibility ▁is ▁removing ▁the ▁egg ▁nucle us ▁or ▁inserting ▁the ▁som atic ▁nucle us ▁causes ▁damage ▁to ▁the ▁cy top last , ▁affect ing ▁re programming ▁ability . ▁ ▁T aking ▁this ▁into ▁account ▁the ▁research ▁group ▁applied ▁their ▁new ▁technique ▁in ▁an ▁attempt ▁to ▁produce ▁human ▁SC NT ▁stem ▁cells . ▁In ▁May ▁ 2 0 1 3 , ▁the ▁Oregon ▁group ▁reported ▁the ▁successful ▁deriv ation ▁of ▁human ▁emb ry onic ▁stem ▁cell ▁lines ▁derived ▁through ▁SC NT , ▁using ▁f etal ▁and ▁infant ▁don or ▁cells . ▁Using ▁M II ▁o ocy tes ▁from ▁volunte ers ▁and ▁their ▁improved ▁SC NT ▁procedure , ▁human ▁clone ▁emb ry os ▁were ▁successfully ▁produced . ▁These ▁emb ry os ▁were ▁of ▁poor ▁quality , ▁lack ing ▁a ▁substantial ▁inner ▁cell ▁mass ▁and ▁poor ly ▁constructed ▁trop he ct od erm . ▁The ▁imper fect ▁emb ry os ▁prevent ed ▁the ▁ac quisition ▁of ▁human ▁E SC .