l ated ▁by ▁Ser / T hr ▁kin ases ▁and ▁thus ▁may ▁be ▁more ▁open ▁to ▁interactions ▁with ▁other ▁N PF s . ▁Having ▁other ▁N PF s ▁bind ▁to ▁the ▁Ar p 2 / 3 ▁complex ▁at ▁the ▁same ▁time ▁as ▁cort act in ▁may ▁enh ance ▁nucle ation ▁site ▁stability . ▁ ▁Location ▁and ▁function ▁in ▁the ▁cell ▁▁ ▁In active ▁cort act in ▁diff uses ▁throughout ▁the ▁cy top las m , ▁but ▁upon ▁ph osph ory lation , ▁the ▁protein ▁begins ▁to ▁target ▁certain ▁areas ▁in ▁the ▁cell . ▁Cort act in - ass isted ▁Ar p 2 / 3 - n uc le ated ▁act in ▁branches ▁are ▁most ▁prominent ▁in ▁the ▁act in ▁cor tex , ▁around ▁the ▁peri ph ery ▁of ▁the ▁cell . ▁A ▁ph osph ory l ated ▁cort act in ▁mon omer ▁bind s ▁to , ▁activ ates , ▁and ▁stabil izes ▁an ▁Ar p 2 / 3 ▁complex ▁on ▁pre ex isting ▁F - act in , ▁which ▁provides ▁a ▁nucle ation ▁site ▁for ▁a ▁new ▁act in ▁branch ▁to ▁form ▁from ▁the ▁“ m other ” ▁fil ament . ▁Branch es ▁formed ▁from ▁cort act in - ass isted ▁nucle ation ▁sites ▁are ▁very ▁stable ; ▁cort act in ▁has ▁been ▁shown ▁to ▁in hib it ▁deb ranch ing . ▁Thus , ▁polym er ization ▁and ▁branch ing ▁of ▁act in ▁is ▁promoted ▁in ▁areas ▁of ▁the ▁cell ▁where ▁cort act in ▁is ▁local ized . ▁ ▁Cort act in ▁is