ster ▁research ▁in ▁this ▁field , ▁and ▁by ▁ 1 9 9 5 ▁ 1 3 ▁of ▁the ▁ 1 9 ▁dru gs ▁approved ▁by ▁the ▁F DA ▁to ▁treat ▁A ID S ▁had ▁received ▁or phan ▁drug ▁design ation , ▁with ▁ 1 0 ▁receiving ▁market ing ▁rights . ▁These ▁are ▁in ▁addition ▁to ▁the ▁ 7 0 ▁designated ▁or phan ▁dru gs ▁designed ▁to ▁treat ▁other ▁H IV ▁related ▁ill ness es . ▁ ▁Ex amples ▁for ▁selected ▁dise ases ▁ ▁C yst ic ▁fib ros is ▁In ▁the ▁ 1 9 8 0 s , ▁people ▁with ▁c yst ic ▁fib ros is ▁rarely ▁lived ▁beyond ▁their ▁early ▁te ens . ▁Dru gs ▁like ▁Pul moz yme ▁and ▁to br am yc in , ▁both ▁developed ▁with ▁aid ▁from ▁the ▁O DA , ▁revolution ized ▁treatment ▁for ▁c yst ic ▁fib ros is ▁patients ▁by ▁significantly ▁impro ving ▁their ▁quality ▁of ▁life ▁and ▁extending ▁their ▁life ▁expect an cies . ▁Now , ▁c yst ic ▁fib ros is ▁patients ▁often ▁surv ive ▁into ▁their ▁th irt ies ▁and ▁some ▁into ▁their ▁f ift ies . ▁ ▁Famil ial ▁hyper ch ol est ero lem ia ▁The ▁ 1 9 8 5 ▁Nobel ▁Prize ▁for ▁medicine ▁went ▁to ▁two ▁research ers ▁for ▁their ▁work ▁related ▁to ▁ ▁famil ial ▁hyper ch ol est ero lem ia , ▁which ▁causes ▁large ▁and ▁rapid ▁increases ▁in ▁ch ol ester ol ▁levels . ▁Their ▁research ▁led ▁to ▁the ▁development ▁of ▁stat in ▁dru gs