ine ) ▁is ▁correl ated ▁with ▁a ▁persistent ▁reduction ▁in ▁the ▁expression ▁of ▁E A AT 2 ▁in ▁the ▁nucle us ▁acc umb ens ▁( NA cc ); ▁the ▁reduced ▁expression ▁of ▁E A AT 2 ▁in ▁this ▁region ▁is ▁imp licated ▁in ▁add ict ive ▁drug - se ek ing ▁behavior . ▁In ▁particular , ▁the ▁long - term ▁d ys reg ulation ▁of ▁gl ut am ate ▁ne uro trans mission ▁in ▁the ▁N Acc ▁of ▁add ict s ▁is ▁associated ▁with ▁an ▁increase ▁in ▁vulner ability ▁to ▁re lapse ▁after ▁re - ex pos ure ▁to ▁the ▁add ict ive ▁drug ▁or ▁its ▁associated ▁drug ▁c ues . ▁Dru gs ▁which ▁help ▁to ▁normal ize ▁the ▁expression ▁of ▁E A AT 2 ▁in ▁this ▁region , ▁such ▁as ▁N - ac et yl c yst e ine , ▁have ▁been ▁proposed ▁as ▁an ▁adj unct ▁ther apy ▁for ▁the ▁treatment ▁of ▁add iction ▁to ▁c oca ine , ▁nic ot ine , ▁alco hol , ▁and ▁other ▁dru gs . ▁ ▁See ▁also ▁D op am ine ▁trans por ters ▁N ore pine phr ine ▁trans por ters ▁Ser ot on in ▁trans por ters ▁N MD A ▁re cept ors ▁A MP A ▁re cept ors ▁K ain ate ▁re cept ors ▁Met ab otrop ic ▁gl ut am ate ▁re cept ors ▁ ▁References ▁ ▁External ▁links ▁▁▁ ▁Category : Am ph et am ine ▁Category : M emb rane ▁prote ins ▁Category : Ne uro trans mit