oven ale ▁at ▁Cas cia ▁di ▁Reg g ello , ▁very ▁close ▁to ▁Mas ac cio ' s ▁h omet own . ▁ ▁It ▁dep ict s ▁the ▁Virgin ▁and ▁Child ▁with ▁ang els ▁in ▁the ▁central ▁panel , ▁St s . ▁Bar th ol ome w ▁and ▁Bla ise ▁on ▁the ▁left ▁panel , ▁and ▁St s . ▁Ju ven al ▁( i . e . ▁San ▁Gi oven ale ) ▁and ▁Anthony ▁Abb ot ▁in ▁the ▁right ▁panel . ▁ ▁The ▁painting ▁has ▁lost ▁much ▁of ▁its ▁original ▁fr aming , ▁and ▁its ▁surface ▁is ▁badly ▁ab rad ed . ▁ ▁Nevertheless , ▁Mas ac cio ' s ▁concern ▁to ▁suggest ▁three - dimensional ity ▁through ▁vol um et ric ▁figures ▁and ▁for esh ort ened ▁forms ▁is ▁apparent , ▁and ▁stands ▁as ▁a ▁rev ival ▁of ▁Gi otto ' s ▁approach , ▁rather ▁than ▁a ▁continu ation ▁of ▁contemporary ▁tr ends . ▁ ▁The ▁second ▁work ▁was ▁perhaps ▁Mas ac cio ' s ▁first ▁collaboration ▁with ▁the ▁older ▁and ▁already - ren owned ▁artist , ▁Mas ol ino ▁da ▁Pan icale ▁( 1 3 8 3 / 4 – c . ▁ 1 4 3 6 ). ▁The ▁circumstances ▁of ▁the ▁two ▁artists ' ▁collaboration ▁are ▁unclear ; ▁since ▁Mas ol ino ▁was ▁consider ably ▁older , ▁it ▁seems ▁likely ▁that ▁he ▁brought ▁Mas ac cio ▁under ▁his ▁wing , ▁but ▁the ▁division ▁of ▁hands ▁in ▁the ▁Virgin ▁and ▁Child ▁with ▁Saint ▁Anne ▁is ▁so ▁marked ▁that ▁it ▁is ▁hard