▁N N RT Is ▁like ▁r il p iv ir ine ▁and ▁et ra vir ine ▁are ▁effective ▁in ▁treatment ▁for ▁H IV ▁stra ins ▁resist ant ▁to ▁ne vi rap ine ▁and ▁other ▁first ▁generation ▁dru gs ▁in ▁that ▁same ▁class . ▁ ▁History ▁Ne vi rap ine ▁was ▁discovered ▁by ▁Karl ▁D . ▁H arg ra ve ▁and ▁colle agues ▁at ▁Bo e hr inger ▁In gel heim ▁Ph arma ce ut ical s , ▁Inc ., ▁one ▁of ▁the ▁Bo e hr inger ▁In gel heim ▁group ▁of ▁companies . ▁It ▁is ▁covered ▁by ▁U . S . ▁Pat ent ▁ 5 , 3 6 6 , 9 7 2 ▁and ▁corresponding ▁foreign ▁pat ents . ▁ ▁Ne vi rap ine ▁was ▁the ▁first ▁N N RT I ▁approved ▁by ▁the ▁U . S . ▁Food ▁and ▁D rug ▁Administration ▁( F DA ). ▁It ▁was ▁approved ▁June ▁ 2 1 , ▁ 1 9 9 6 ▁for ▁adult s ▁and ▁September ▁ 1 1 , ▁ 1 9 9 8 ▁for ▁children . ▁It ▁was ▁also ▁approved ▁in ▁Europe ▁in ▁ 1 9 9 7 . ▁ ▁Society ▁and ▁culture ▁Form er ▁U . S . ▁President ▁George ▁W . ▁Bush ' s ▁P E PF AR ▁fund ing ▁of ▁$ 5 0 0 ▁million ▁to ▁help ▁combat ▁the ▁African ▁A ID S ▁ep ide mic ▁included ▁ne vi rap ine , ▁among ▁other ▁medic ations ▁and ▁programs . ▁ ▁References ▁ ▁Category : H ep at ot ox