et ics ▁ ▁uses ▁bio in form atic ▁methods ▁to ▁complement ▁experimental ▁research ▁in ▁ep igen et ics . ▁Due ▁to ▁the ▁recent ▁explos ion ▁of ▁ep igen ome ▁datasets , ▁computational ▁methods ▁play ▁an ▁increasing ▁role ▁in ▁all ▁areas ▁of ▁ep igen etic ▁research . ▁ ▁Definition ▁Research ▁in ▁computational ▁ep igen et ics ▁compr ises ▁the ▁development ▁and ▁application ▁of ▁bio in format ics ▁methods ▁for ▁solving ▁ep igen etic ▁questions , ▁as ▁well ▁as ▁computational ▁data ▁analysis ▁and ▁theoretical ▁model ing ▁in ▁the ▁context ▁of ▁ep igen et ics . ▁This ▁includes ▁mod elling ▁of ▁the ▁effects ▁of ▁hist one ▁and ▁DNA ▁C p G ▁island ▁m eth yl ation . ▁ ▁Current ▁research ▁areas ▁ ▁Ep igen etic ▁data ▁processing ▁and ▁analysis ▁ ▁Vari ous ▁experimental ▁techniques ▁have ▁been ▁developed ▁for ▁gen ome - wide ▁mapping ▁of ▁ep igen etic ▁information , ▁the ▁most ▁widely ▁used ▁being ▁Ch IP - on - ch ip , ▁Ch IP - seq ▁and ▁bis ulf ite ▁sequ encing . ▁All ▁of ▁these ▁methods ▁generate ▁large ▁amounts ▁of ▁data ▁and ▁require ▁efficient ▁ways ▁of ▁data ▁processing ▁and ▁quality ▁control ▁by ▁bio in form atic ▁methods . ▁ ▁Ep igen ome ▁prediction ▁A ▁substantial ▁amount ▁of ▁bio in form atic ▁research ▁has ▁been ▁devoted ▁to ▁the ▁prediction ▁of ▁ep igen etic ▁information ▁from ▁characteristics ▁of ▁the ▁gen ome ▁sequence . ▁Such ▁predictions ▁serve ▁a ▁dual ▁purpose . ▁First , ▁accurate ▁ep igen ome ▁predictions ▁can ▁substitute ▁for ▁experimental ▁data , ▁to ▁some ▁degree ,