▁in ▁north western ▁Al ger ia . ▁ ▁References ▁ ▁Category : Pop ulated ▁places ▁in ▁Sa ï da ▁Province ▁Category : Comm unes ▁of ▁Al ger ia <0x0A> </s> ▁Pe pt id yl - pro ly l ▁c is - trans ▁is omer ase ▁F KB P 1 A ▁is ▁an ▁en zym e ▁that ▁in ▁humans ▁is ▁encoded ▁by ▁the ▁F KB P 1 A ▁gene . ▁ ▁Function ▁▁ ▁The ▁protein ▁encoded ▁by ▁this ▁gene ▁is ▁a ▁member ▁of ▁the ▁imm un oph il in ▁protein ▁family , ▁which ▁play ▁a ▁role ▁in ▁imm un or eg ulation ▁and ▁basic ▁cell ular ▁processes ▁involving ▁protein ▁fol ding ▁and ▁tra ff ick ing . ▁This ▁encoded ▁protein ▁is ▁a ▁c is - trans ▁pro ly l ▁is omer ase ▁that ▁bind s ▁the ▁imm unos upp ress ants ▁FK 5 0 6 ▁( tac rol im us ) ▁and ▁rap am yc in ▁( si rol im us ). ▁It ▁interact s ▁with ▁several ▁int rac ell ular ▁signal ▁trans du ction ▁prote ins ▁including ▁type ▁I ▁T G F - beta ▁re ceptor . ▁It ▁also ▁interact s ▁with ▁multiple ▁int rac ell ular ▁calci um ▁release ▁channels ▁including ▁the ▁t et ram er ic ▁ske let al ▁mus cle ▁r yan od ine ▁re ceptor . ▁In ▁mouse , ▁delet ion ▁of ▁this ▁hom olog ous ▁gene ▁causes ▁con gen ital ▁heart ▁dis order ▁known ▁as ▁non comp action ▁of ▁left ▁vent ric ular ▁my oc ard ium .