lo vir . ▁Later , ▁Prof ▁Sch a ef fer ▁continued ▁the ▁development ▁of ▁a cyc lo vir ▁at ▁B urr ough s ▁Welcome ▁& ▁Company , ▁with ▁ph arm ac ologist ▁Ger tr ude ▁B . ▁El ion ▁who ▁was ▁awarded ▁the ▁ 1 9 8 8 ▁Nobel ▁Prize ▁in ▁Medicine , ▁in ▁part , ▁for ▁the ▁development ▁of ▁a cyc lo vir . ▁Dr . ▁V ince ▁continued ▁his ▁work ▁on ▁ant iv iral ▁drug ▁candidates ▁at ▁the ▁University ▁of ▁Minnesota , ▁where ▁he ▁went ▁on ▁to ▁develop ▁car b oc yc lic ▁nucle os ides ▁term ed ▁' car b ov irs '. ▁This ▁class ▁of ▁medic inal ▁agents ▁included ▁the ▁drug ▁ab ac av ir . ▁Ab ac av ir ▁was ▁commercial ized ▁by ▁Gla x o Smith K line ▁as ▁Z i agen ® ▁for ▁the ▁treatment ▁of ▁A ID S . ▁Sales ▁from ▁Z i agen ® ▁have ▁resulted ▁in ▁generation ▁of ▁more ▁than ▁ 6 0 0 ▁million ▁US ▁dollars ▁in ▁roy alt ies ▁for ▁the ▁University ▁of ▁Minnesota . ▁ ▁His ▁synth esis ▁of ▁ab ac av ir ▁made ▁use ▁of ▁a ▁b icy clic ▁ γ - la ct am , ▁ 2 - az ab icy clo [ 2 . 2 . 1 ] he pt - 5 - en - 3 - one , ▁as ▁a ▁chemical ▁prec ursor . ▁In ▁recognition ▁of ▁his ▁contribution ▁to ▁the ▁development ▁of ▁this ▁field , ▁Chem ical ▁and ▁Engineering ▁News ▁gave ▁this ▁mole c ule