▁association ▁with ▁se cur in ) ▁to ▁cle ave ▁the ▁kle is in ▁sub unit . ▁An ▁alpha - k le is in ▁is ▁associated ▁with ▁the ▁coh es in ▁complex , ▁linking ▁both ▁S MC ▁ 3 ▁and ▁S MC ▁ 1 ▁together , ▁with ▁the ▁exact ▁kle is in ▁varying ▁between ▁mit osis ▁and ▁me ios is ▁( S cc 1 ▁and ▁Rec 8 ▁respectively ), ▁and ▁its ▁cle av age ▁ultimately ▁leads ▁to ▁the ▁removal ▁of ▁coh es in ▁from ▁chrom os om es . ▁ ▁Dis soci ation ▁of ▁sister ▁chrom at ids ▁coh es ion ▁defines ▁an aph ase ▁on set , ▁which ▁establish es ▁two ▁sets ▁of ▁identical ▁chrom os om es ▁at ▁each ▁pole ▁of ▁the ▁cell ▁( tel oph ase ). ▁Then ▁the ▁two ▁daughter ▁cells ▁separate , ▁and ▁a ▁new ▁round ▁of ▁the ▁cell ▁cycle ▁fresh ly ▁starts ▁in ▁each ▁one , ▁at ▁the ▁stage ▁of ▁G 0 . ▁When ▁cells ▁are ▁ready ▁to ▁divide , ▁because ▁cell ▁size ▁is ▁big ▁enough ▁or ▁because ▁they ▁receive ▁the ▁appropriate ▁stim ulus , ▁they ▁activ ate ▁the ▁mechanism ▁to ▁enter ▁into ▁the ▁G 1 ▁stage ▁of ▁cell ▁cycle , ▁and ▁they ▁duplicate ▁most ▁organ elles ▁during ▁S ▁( syn thesis ) ▁phase , ▁including ▁their ▁cent ros ome . ▁Therefore , ▁when ▁the ▁cell ▁division ▁process ▁will ▁end , ▁each ▁daughter ▁cell ▁will ▁receive ▁a ▁complete ▁set ▁of ▁organ elles . ▁At ▁the ▁same ▁time , ▁during ▁S ▁phase ▁all ▁cells ▁must ▁duplicate ▁their ▁DNA ▁very