lo xy )- 8 - m eth yl - 8 - az ab icy clo ▁[ 3 . 2 . 1 ] ▁oct ane - 2 - car box am ido - hex ano ic ▁acid ▁ ▁C oca ine ▁ha pt ens ▁that ▁create ▁catal yt ic ▁anti - b od ies ▁require ▁trans itional ▁states ▁as ▁affected ▁in ▁v ivo . ▁ ▁Struct ural / Function al ▁intermediate ▁analog ues ▁ ▁Trop ane ▁( non - ec gon ine ) ▁analog ues ▁The ▁first ▁comp ound ▁of ▁those ▁categor ized ▁as ▁an ▁" inter mediate ▁analog " ▁in ▁the ▁series ▁presented ▁immediately ▁below ▁( para - flu oro - ben zo yl - t rop ane ), ▁although ▁several ▁modifications ▁distant ▁from ▁its ▁c oca ine ▁parent ▁structure , ▁fits ▁every ▁technical ▁criteria ▁of ▁a ▁strict ▁analog ▁type ▁to ▁c oca ine . ▁It ▁is ▁given ▁here , ▁however , ▁as ▁the ▁nearest ▁rel ational ▁structure ▁along ▁the ▁inst anced ▁spectrum ▁traject ory ▁of ▁subst itu ent ▁permut ations ▁of ▁those ▁following ▁from ▁it ▁( in ▁this ▁first ▁section ), ▁and ▁set ▁it ▁as ▁the ▁beginning ▁ing ress ▁point ▁for ▁the ▁range ▁of ▁those ▁compar able ▁but ▁sufficiently ▁diver gent ▁from ▁those ▁in ▁full ▁hom ogene ity ▁of ▁structure ▁and ▁function ▁to ▁distinguish ▁a ▁more ▁median ▁class ▁that ▁is ▁not ▁in ▁as ▁much ▁a ▁rig id ▁s tere ot yp ed ▁pla cement ▁to ▁both ▁( and ▁not ▁yet ▁approaching ▁the ▁fr inge ▁or ▁outer most ▁terms ▁allowing ▁inclusion ) ▁▁