at itis ▁and ▁an ap hy la xis . ▁Saf ety ▁profiles ▁of ▁newer ▁dru gs ▁are ▁often ▁not ▁as ▁well ▁established ▁as ▁for ▁those ▁that ▁have ▁a ▁long ▁history ▁of ▁use . ▁ ▁Common ▁side - effect s ▁include ▁di arr he a , ▁resulting ▁from ▁dis ruption ▁of ▁the ▁species ▁composition ▁in ▁the ▁int est inal ▁fl ora , ▁resulting , ▁for ▁example , ▁in ▁over g row th ▁of ▁path ogen ic ▁b acter ia , ▁such ▁as ▁Clo str id ium ▁diff icile . ▁Ant ib acter ial s ▁can ▁also ▁affect ▁the ▁v ag inal ▁fl ora , ▁and ▁may ▁lead ▁to ▁over g row th ▁of ▁ye ast ▁species ▁of ▁the ▁genus ▁Cand ida ▁in ▁the ▁vul vo - v ag inal ▁area . ▁Add itional ▁side ▁effects ▁can ▁result ▁from ▁interaction ▁with ▁other ▁dru gs , ▁such ▁as ▁the ▁possibility ▁of ▁tend on ▁damage ▁from ▁the ▁administration ▁of ▁a ▁qu in ol one ▁ant ib i otic ▁with ▁a ▁system ic ▁cort ic ost ero id . ▁ ▁Some ▁ant ib iot ics ▁may ▁also ▁damage ▁the ▁mit och ond r ion , ▁a ▁b acter ia - der ived ▁organ elle ▁found ▁in ▁e uk ary otic , ▁including ▁human , ▁cells . ▁M ito ch ond rial ▁damage ▁cause ▁ox id ative ▁stress ▁in ▁cells ▁and ▁has ▁been ▁suggested ▁as ▁a ▁mechanism ▁for ▁side ▁effects ▁from ▁flu oro quin ol ones . ▁They ▁are ▁also ▁known ▁to ▁affect ▁ch lor op last s .