ly ▁enc odes ▁the ▁D - am ino ▁acid ▁ox id ase ▁activ ator , ▁may ▁be ▁involved ▁in ▁the ▁development ▁of ▁sch iz op hren ia . ▁ ▁Reg ulation ▁Bass oon ▁protein ▁and ▁p L G 7 2 , ▁are ▁the ▁current ▁known ▁prote ins ▁to ▁phys ically ▁interact ▁and ▁mod ulate ▁human ▁D AA O . ▁pl G 7 2 ▁is ▁the ▁product ▁of ▁the ▁prim ate - specific ▁G 7 2 ▁gene , ▁and ▁higher ▁levels ▁of ▁both ▁were ▁observed ▁in ▁sch iz op hren ia ▁patients . ▁ ▁Inter action ▁of ▁pl G 7 2 ▁with ▁h D AA O ▁was ▁observed ▁to ▁cause ▁a ▁time - dependent ▁in activ ation ▁with ▁the ▁ox id ase . ▁This ▁is ▁believed ▁to ▁be ▁caused ▁by ▁pl G 7 2 ▁binding ▁limit ing ▁the ▁amount ▁of ▁the ▁en zym e ▁that ▁is ▁catal yt ically ▁compet ent , ▁and ▁can ▁be ▁neg ated ▁by ▁the ▁c of actor ▁or ▁any ▁active - site ▁lig ands . ▁The ▁pl G 7 2 ▁structure ▁is ▁not ▁fully ▁determined ▁so ▁the ▁specific ▁physical ▁interaction ▁with ▁h D AA O ▁is ▁not ▁completely ▁understood ▁as ▁well . ▁Exper iments ▁with ▁the ▁bass on ▁protein ▁and ▁h D AA O ▁has ▁resulted ▁with ▁a ▁decrease ▁in ▁en zym atic ▁activity ▁similar ▁to ▁pl G 7 2 . ▁Research ers ▁suspect ▁the ▁bass oon ▁protein ▁prevents ▁D - Ser ine ▁de ple tion ▁particularly ▁in ▁the ▁pres yn apt ic ▁neur on . ▁ ▁Additionally ,