ized ▁phen ot yp ic ▁screen ▁to ▁determine ▁the ▁effects ▁of ▁delet ion . ▁Tw enty ▁one ▁tests ▁were ▁carried ▁out ▁on ▁mut ant ▁m ice ▁and ▁three ▁significant ▁ab normal ities ▁were ▁observed . ▁Fem ale ▁hom o zy g ote ▁mut ants ▁had ▁decre ased ▁circul ating ▁gl uc ose ▁levels . ▁Male ▁hem iz yg ous ▁mut ants ▁had ▁an ▁increased ▁sus cept ibility ▁to ▁b acter ial ▁in fection . ▁Both ▁sex es ▁had ▁various ▁ab normal ▁pl asma ▁chem istry ▁parameters . ▁ ▁Z eb raf ish ▁ ▁A ▁knock out ▁z eb raf ish ▁line ▁was ▁generated ▁in ▁ 2 0 1 4 ▁using ▁the ▁z inc - f inger ▁nuc lease ▁( Z F N )- medi ated ▁target ed ▁gene ▁editing ▁system . ▁Similar ▁to ▁human ▁patients , ▁the ▁z eb raf ish ▁lar va e ▁exhib ited ▁ne uro log ical ▁and ▁behavior al ▁def ic ien cies . ▁They ▁demonstrated ▁reduced ▁locomot or ▁activity , ▁alter ed ▁my elin - related ▁gen es ▁and ▁neur on - specific ▁def ic ien cies ▁in ▁circuit ▁formation . ▁ ▁X en opus ▁ ▁Expression ▁of ▁m ct 8 ▁has ▁been ▁character ised ▁in ▁X en opus ▁la e vis ▁and ▁X en opus ▁tropical is . ▁ ▁See ▁also ▁▁ ▁Sol ute ▁car rier ▁family ▁ ▁References ▁ ▁Further ▁reading ▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁ ▁▁▁▁▁▁▁▁▁▁▁▁▁▁▁ ▁Category : Sol ute ▁car rier ▁family ▁Category : Gen es ▁mut ated ▁in ▁m ice <0x0A> </s> ▁Gra ž ina ▁Did ž