▁in ▁a ▁speech ▁from ▁Fort ▁Det rick . ▁The ▁statement ▁ended , ▁un condition ally , ▁all ▁U . S . ▁off ensive ▁bi ological ▁weapons ▁programs . ▁N ixon ▁noted ▁that ▁bi ological ▁weapons ▁were ▁un re li able ▁and ▁stated : ▁ ▁The ▁United ▁States ▁shall ▁ren ounce ▁the ▁use ▁of ▁le th al ▁bi ological ▁agents ▁and ▁weapons , ▁and ▁all ▁other ▁methods ▁of ▁bi ological ▁war fare . ▁The ▁United ▁States ▁will ▁conf ine ▁its ▁bi ological ▁research ▁to ▁def ensive ▁measures ▁such ▁as ▁imm un ization ▁and ▁safety ▁measures . ▁ ▁In ▁his ▁speech ▁N ixon ▁called ▁his ▁move ▁" un pre ced ented "; ▁and ▁it ▁was ▁in ▁fact ▁the ▁first ▁review ▁of ▁the ▁U . S . ▁bi ological ▁war fare ▁program ▁since ▁ 1 9 5 4 . ▁Despite ▁the ▁lack ▁of ▁review , ▁the ▁bi ological ▁war fare ▁program ▁had ▁increased ▁in ▁cost ▁and ▁size ▁since ▁ 1 9 6 1 ; ▁when ▁N ixon ▁ended ▁the ▁program ▁the ▁budget ▁was ▁$ 3 0 0 ▁million ▁ann ually . ▁N ixon ' s ▁statement ▁conf ined ▁all ▁bi ological ▁weapons ▁research ▁to ▁def ensive - only ▁and ▁ordered ▁the ▁destruction ▁of ▁the ▁existing ▁U . S . ▁bi ological ▁ar sen al . ▁ ▁U . S . ▁bi ological ▁weapons ▁stock s ▁were ▁destroyed ▁over ▁the ▁next ▁few ▁years . ▁A ▁$ 1 2 ▁million ▁dispos al ▁plan ▁was ▁undert aken ▁at ▁P ine ▁Bl uff ▁Ar sen al , ▁where ▁all ▁U