app eared ▁in ▁the ▁Mar m ara ▁and ▁re - est ab lished ▁a ▁base ▁at ▁Cy z icus , ▁from ▁there ▁they ▁ra ided ▁the ▁By z antine ▁coast s ▁almost ▁at ▁will . ▁Finally ▁in ▁ 6 7 6 , ▁Mu aw iy ah ▁sent ▁an ▁army ▁to ▁invest ▁Constantin ople ▁from ▁land ▁as ▁well , ▁beginning ▁the ▁First ▁Arab ▁Sie ge ▁of ▁the ▁city . ▁Const antine ▁IV ▁( r . ▁ 6 6 1 – 6 8 5 ) ▁however ▁used ▁a ▁dev ast ating ▁new ▁weapon ▁that ▁came ▁to ▁be ▁known ▁as ▁" G reek ▁fire ", ▁invent ed ▁by ▁a ▁Christian ▁refuge e ▁from ▁Sy ria ▁named ▁K all in ik os ▁of ▁H eli opol is , ▁to ▁decis ively ▁defeat ▁the ▁attack ing ▁Um ay y ad ▁n avy ▁in ▁the ▁Sea ▁of ▁Mar m ara , ▁resulting ▁in ▁the ▁lif ting ▁of ▁the ▁sie ge ▁in ▁ 6 7 8 . ▁The ▁returning ▁Muslim ▁fleet ▁suffered ▁further ▁losses ▁due ▁to ▁storm s , ▁while ▁the ▁army ▁lost ▁many ▁men ▁to ▁the ▁them atic ▁arm ies ▁who ▁attacked ▁them ▁on ▁their ▁route ▁back . ▁ ▁Among ▁those ▁killed ▁in ▁the ▁sie ge ▁was ▁E y up , ▁the ▁standard ▁bear er ▁of ▁Muham med ▁and ▁the ▁last ▁of ▁his ▁compan ions ; ▁to ▁Muslim s ▁today , ▁his ▁tomb ▁is ▁considered ▁one ▁of ▁the ▁h oli est ▁sites ▁in ▁Ist an bul . ▁The ▁By z antine ▁victory ▁over ▁the ▁inv ading ▁Um ay y