▁plate let ▁activation , ▁but ▁is ▁not ▁sufficient ▁for ▁a ▁full ▁plate let ▁aggreg ation ▁in ▁response ▁to ▁AD P . ▁c AMP ▁in hib its ▁plate let ▁aggreg ation , ▁and ▁decre ased ▁amounts ▁of ▁c AMP ▁in ▁plate lets ▁lead ▁to ▁plate let ▁aggreg ation . ▁▁ ▁The ▁P GE 1 ▁re agent ▁is ▁used ▁together ▁with ▁the ▁AD P ▁test ▁for ▁two ▁purposes : ▁the ▁assess ment ▁of ▁AD P ▁high ▁sens itivity ▁( HS ) ▁and ▁of ▁positive ▁controls ▁of ▁the ▁AD P test . ▁ ▁When ▁a ▁small ▁amount ▁of ▁P GE 1 ▁( 2 0 ▁ µ l ) ▁is ▁added ▁to ▁the ▁AD P test , ▁it ▁indu ces ▁a ▁moder at ▁in hib ition ▁of ▁aggreg ation ▁in ▁normal ▁samples , ▁but ▁greatly ▁increases ▁the ▁sens itivity ▁of ▁plate lets ▁to ▁in hib ition ▁by ▁c lop id og rel . ▁This ▁is ▁why ▁the ▁modified ▁test ▁is ▁called ▁" High ▁S ens itivity ". ▁Adding ▁ 5 0 ▁ µ l ▁of ▁P GE 1 ▁ ▁to ▁the ▁AD P test ▁leads ▁to ▁a ▁strong ▁in hib ition ▁of ▁AD P ▁induced ▁aggreg ation , ▁and ▁is ▁used ▁for ▁assess ment ▁of ▁positive ▁controls ▁of ▁the ▁AD P test . ▁ ▁References ▁ ▁Category : Med ical ▁tests ▁Category : Med ical ▁testing ▁equipment <0x0A> </s> ▁L act o fer rin ▁( L F ), ▁also ▁known ▁as ▁la ct otr ans fer rin ▁( LT F ), ▁is ▁a ▁mult if unction al