▁cells ▁are ▁identical : ▁G AU CA U U A ▁- 3 ' OH . ▁ ▁The ▁conservation ▁of ▁this ▁sequence ▁between ▁such ▁dist antly ▁related ▁e uk ary otes ▁imp lied ▁that ▁this ▁nucle ot ide ▁tract ▁played ▁an ▁important ▁role ▁in ▁the ▁cell . ▁ ▁Since ▁this ▁conser ved ▁sequence ▁contained ▁the ▁complement ▁of ▁each ▁of ▁the ▁three ▁e uk ary otic ▁term ination ▁cod ons ▁( U AA , ▁U AG ▁and ▁U GA ) ▁it ▁was ▁proposed ▁to ▁have ▁a ▁role ▁in ▁the ▁term ination ▁of ▁protein ▁synth esis ▁in ▁e uk ary otes . ▁ ▁A ▁similar ▁role ▁for ▁the ▁ 3 ' ▁end ▁of ▁ 1 6 S ▁r R NA ▁in ▁recogn ising ▁term ination ▁triple ts ▁in ▁E . coli ▁was ▁proposed ▁in ▁ 1 9 7 4 ▁by ▁Sh ine ▁and ▁Dal gar no ▁on ▁the ▁basis ▁of ▁complement ar ity ▁relationships ▁between ▁the ▁ 3 '- term inal ▁U U A - OH ▁in ▁ 1 6 S ▁r R NA ▁and ▁E . coli ▁term ination ▁cod ons . ▁ ▁In ▁F 1 ▁ph age , ▁a ▁class ▁of ▁vir uses ▁that ▁inf ect ▁b acter ia , ▁the ▁sequence ▁coding ▁for ▁the ▁first ▁few ▁am ino ▁ac ids ▁often ▁contains ▁term ination ▁triple ts ▁in ▁the ▁two ▁un used ▁reading ▁frames . ▁In ▁a ▁comment ary ▁on ▁this ▁paper , ▁it ▁was ▁noted ▁that ▁complement ary ▁base ▁pair ing ▁with ▁the ▁ 3 '- ter minus ▁of ▁ 1 6 S