▁att ain ▁ren own . ▁ ▁After ▁the ▁creation ▁of ▁Or issa ▁as ▁a ▁separate ▁province ▁in ▁ 1 9 3 6 , ▁Pat na ▁continued ▁as ▁the ▁capital ▁of ▁Bi har ▁province ▁under ▁the ▁British ▁Raj . ▁ ▁Pat na ▁played ▁a ▁major ▁role ▁in ▁the ▁Indian ▁independence ▁struggle . ▁Most ▁notable ▁are ▁the ▁Cham par an ▁movement ▁against ▁the ▁Ind igo ▁plant ation ▁and ▁the ▁Qu it ▁India ▁Mov ement ▁of ▁ 1 9 4 2 .. ▁ ▁Post - Ind ep end ence ▁ ▁Gallery ▁: ▁Pat na ▁as ▁Capital ▁ ▁See ▁also ▁▁ ▁History ▁of ▁Bi har ▁ ▁References ▁▁ ▁Category : History ▁of ▁Pat na ▁Category : Pat na <0x0A> </s> ▁R ho GE F ▁domain ▁describes ▁two ▁distinct ▁struct ural ▁domains ▁with ▁ ▁gu an ine ▁nucle ot ide ▁exchange ▁factor ▁( GE F ) ▁activity ▁to ▁reg ulate ▁small ▁G TP ases ▁in ▁the ▁R ho ▁family . ▁R ho ▁small ▁G TP ases ▁are ▁in active ▁when ▁bound ▁to ▁G DP ▁but ▁active ▁when ▁bound ▁to ▁G TP ; ▁R ho GE F ▁domains ▁in ▁prote ins ▁are ▁able ▁to ▁promote ▁G DP ▁release ▁and ▁G TP ▁binding ▁to ▁activ ate ▁specific ▁R ho ▁family ▁members , ▁including ▁R ho A , ▁R ac 1 ▁and ▁C dc 4 2 . ▁ ▁The ▁largest ▁class ▁of ▁R ho GE F s ▁is ▁composed ▁of ▁prote ins ▁containing ▁the ▁" D bl - hom ology " ▁( D H ) ▁domain , ▁which ▁almost ▁always ▁is