▁host ▁and ▁the ▁human ▁host ▁is ▁the ▁intermediate . ▁When ▁the ▁An oph eles ▁mos qu ito ▁takes ▁a ▁blood ▁me al ▁from ▁an ▁inf ected ▁individual , ▁gam et ocy tes ▁are ▁ing ested ▁from ▁the ▁inf ected ▁person . ▁A ▁process ▁known ▁as ▁ex flag ell ation ▁of ▁the ▁micro g am et ocy te ▁soon ▁ens ues ▁and ▁up ▁to ▁eight ▁mobile ▁micro g am etes ▁are ▁formed . ▁ ▁Sex ual ▁stage ▁Following ▁fert il ization ▁of ▁the ▁mac rog am ete , ▁a ▁mobile ▁ook in ete ▁is ▁formed , ▁which ▁pen etr ates ▁the ▁per it rop ic ▁memb rane ▁surrounding ▁the ▁blood ▁me al ▁and ▁travel s ▁to ▁the ▁outer ▁wall ▁of ▁the ▁mid - g ut ▁of ▁the ▁mos qu ito . ▁The ▁o oc yst ▁then ▁develop s ▁under ▁the ▁bas al ▁memb rane ▁and ▁after ▁a ▁period ▁of ▁two ▁to ▁three ▁weeks ▁a ▁variable ▁amount ▁of ▁sp or oz o ites ▁are ▁produced ▁within ▁each ▁o oc yst . ▁The ▁number ▁of ▁sp or oz o ites ▁that ▁are ▁produced ▁var ies ▁with ▁temperature ▁and ▁can ▁range ▁from ▁anywhere ▁between ▁many ▁hundreds ▁to ▁a ▁few ▁thousand . ▁Event ually , ▁the ▁o oc yst ▁ru pt ures ▁and ▁the ▁sp or oz o ites ▁are ▁released ▁into ▁the ▁hem oco el ▁of ▁the ▁mos qu ito . ▁The ▁sp or oz o ites ▁are ▁then ▁carried ▁by ▁the ▁circul ation ▁of ▁the ▁hem ol ym ph ▁to ▁the ▁sal iv ary ▁g lands