▁kid ney . ▁ ▁Function ▁▁ ▁The ▁protein ▁encoded ▁by ▁this ▁gene ▁is ▁a ▁type ▁III ▁g ly cop rote in ▁that ▁is ▁located ▁primarily ▁in ▁limit ing ▁memb ran es ▁of ▁l ys os om es ▁and ▁end os om es . ▁Studies ▁of ▁the ▁similar ▁protein ▁in ▁m ice ▁and ▁rat ▁suggested ▁that ▁this ▁protein ▁may ▁particip ate ▁in ▁memb rane ▁transport ation ▁and ▁the ▁re organ ization ▁of ▁end os om al / ly s os om al ▁compart ment . ▁In ▁rat ▁he p atic ▁cells , ▁LI MP - 2 ▁exhib ited ▁a ▁half - life ▁for ▁internal ization ▁and ▁l ys os om al ▁transport ▁of ▁ 3 2 ▁min ▁and ▁ 2 . 0 ▁h , ▁respectively , ▁which ▁res emble d ▁that ▁of ▁well - known ▁l ys os om al ▁prote ins , ▁lamp - 1 ▁and ▁lamp - 2 , ▁al beit ▁different ▁am ino ▁acid ▁sequences ▁in ▁their ▁cy top las mic ▁t ails . ▁ ▁LI MP 2 ▁has ▁recently ▁been ▁identified ▁as ▁a ▁novel ▁component ▁of ▁inter cal ated ▁disc s ▁in ▁card iac ▁mus cle . ▁Inter cal ated ▁disc s ▁are ▁composed ▁of ▁gap ▁j unction s , ▁ad her ens ▁j unction s ▁and ▁des mos om es , ▁and ▁are ▁critical ▁for ▁the ▁mechanical ▁and ▁elect rical ▁coupling ▁of ▁adjacent ▁card iom y ocy tes . ▁The ▁discovery ▁of ▁LI MP - 2 ▁as ▁a ▁component ▁of ▁this ▁complex ▁came ▁about ▁from ▁a ▁gen etic ▁screen