ins , ▁such ▁as ▁M 1 3 . ▁In ▁the ▁absence ▁of ▁calci um , ▁the ▁circular ly ▁permut ated ▁flu ores cent ▁prote ins ▁exist ▁in ▁a ▁poor ly ▁flu ores cent ▁state ▁due ▁to ▁a ▁water ▁path way ▁that ▁enables ▁pro ton ation ▁of ▁the ▁chrom oph ore ▁and ▁poor ▁abs orb ance ▁at ▁the ▁exc itation ▁w avel ength s . ▁ ▁Ca 2 + ▁binding ▁to ▁the ▁cal mod ul in ▁mo iety ▁results ▁in ▁a ▁struct ural ▁shift ▁that ▁elimin ates ▁this ▁sol vent ▁path way , ▁rapid ▁de - pro ton ation ▁of ▁the ▁chrom oph ore , ▁and ▁bright ▁flu ores c ence . ▁ ▁See ▁also ▁▁ ▁Opt ogen et ics ▁ ▁References ▁▁ ▁Category : S ens ors ▁Category : Pro te ins ▁Category : B io chem istry ▁methods ▁Category : Cell ▁imag ing ▁Category : Cal ci um ▁Category : Cal ci um ▁signal ing <0x0A> </s> ▁Franco ▁Zur lo ▁( born ▁ 4 ▁October ▁ 1 9 4 0 ) ▁is ▁an ▁Italian ▁box er . ▁He ▁competed ▁in ▁the ▁men ' s ▁b ant am weight ▁event ▁at ▁the ▁ 1 9 6 4 ▁Summer ▁Olympics . ▁At ▁the ▁ 1 9 6 4 ▁Summer ▁Olympics ▁he ▁defeated ▁Mik h ail ▁Mit se v ▁of ▁Bulg aria , ▁before ▁losing ▁to ▁O leg ▁Gr ig ory ev ▁of ▁the ▁Soviet ▁Union . ▁ ▁References ▁ ▁External ▁links ▁▁▁ ▁Category : 1 9 4 0 ▁birth s ▁Category : L iving