, S - di phen yl s ul fil im ine ▁and ▁sul fo xim ines ▁such ▁as ▁m eth yl phen yl s ul fo xim ine : ▁ ▁Pre par ation ▁Most ▁sul fil im ines ▁are ▁N - subst it uted ▁with ▁electron - with draw ing ▁groups . ▁These ▁comp ounds ▁are ▁typically ▁prepared ▁by ▁ox id ation ▁of ▁th io eth ers ▁with ▁elect roph il ic ▁am ine ▁re ag ents , ▁such ▁as ▁ch lor am ine - T ▁in ▁the ▁presence ▁of ▁a ▁base : ▁R 2 S ▁+ ▁Cl N HT s ▁→ ▁R 2 S = NT s ▁+ ▁H Cl ▁ ▁An ▁alternative ▁route ▁involves ▁re actions ▁of ▁elect roph il ic ▁sul fur ▁comp ounds ▁with ▁am ines . ▁The ▁lim idos ulf on ium ▁re ag ents ▁provide ▁a ▁source ▁of ▁" Me 2 S 2 + ", ▁which ▁are ▁attacked ▁by ▁am ines . ▁ ▁Sul fil im ine ▁b onds ▁in ▁prote ins ▁Sul fil im ine ▁b onds ▁stabil ize ▁col lagen ▁IV ▁str ands ▁found ▁in ▁the ▁ext rac ell ular ▁matrix ▁and ▁arose ▁at ▁least ▁ 5 0 0 ▁my a . ▁These ▁b onds ▁c oval ently ▁connect ▁hydro xy ly s ine ▁and ▁m eth ion ine ▁resid ues ▁of ▁adjacent ▁pol ype pt ide ▁str ands ▁to ▁form ▁a ▁larger ▁col lagen ▁tr imer . ▁ ▁References ▁ ▁Category : Function al ▁groups ▁Category : N it ro gen ▁comp ounds ▁Category