▁r R NA ▁might ▁serve ▁to ▁abort ▁pe pt ide ▁bond ▁formation ▁after ▁out - of - phase ▁init iation . ▁ ▁Se quence ▁and ▁protein ▁expression ▁Mut ations ▁in ▁the ▁Sh ine - D al gar no ▁sequence ▁can ▁reduce ▁or ▁increase ▁translation ▁in ▁pro k ary otes . ▁This ▁change ▁is ▁due ▁to ▁a ▁reduced ▁or ▁increased ▁m R NA - rib os ome ▁pair ing ▁efficiency , ▁as ▁ev iden ced ▁by ▁the ▁fact ▁that ▁compens atory ▁mut ations ▁in ▁the ▁ 3 '- term inal ▁ 1 6 S ▁r R NA ▁sequence ▁can ▁restore ▁translation . ▁ ▁See ▁also ▁ ▁K oz ak ▁cons ensus ▁sequence , ▁the ▁sequence ▁that ▁targets ▁the ▁rib os ome ▁to ▁the ▁init iation ▁cod on ▁in ▁verte br ates . ▁ ▁Pro k ary otic ▁translation ▁ ▁References ▁ ▁Further ▁reading ▁▁▁ ▁H ale ▁W G , ▁Marg ham ▁J P , ▁Sau nd ers ▁V A ▁ed s ▁( 1 9 9 5 ) ▁Collins ▁Dictionary ▁of ▁Bi ology , ▁( 2 nd ▁ed ) ▁Sh ine - D al gar no ▁( SD ) ▁sequence . ▁p ▁ 5 6 5 . ▁▁▁ ▁Lew in , ▁B . ▁( 1 9 9 4 ) ▁Gen es ▁V . ▁ ▁Oxford ▁University ▁Press . ▁pp ▁ 1 7 9 , ▁ 2 6 9 . ▁▁▁ ▁Al berts ▁B , ▁B ray ▁D , ▁Lewis ▁J , ▁ ▁R aff ▁M , ▁ ▁Roberts ▁K , ▁Watson ▁J D ▁( 1