▁for ▁foot ▁related ▁problems , ▁and ▁such ▁hospital ▁adm issions ▁are ▁about ▁ 1 3 ▁days ▁longer ▁than ▁for ▁di abet ics ▁without ▁foot ▁related ▁adm issions . ▁Appro xim ately ▁ 3 5 ▁to ▁ 4 0 ▁percent ▁of ▁ul cers ▁rec ur ▁within ▁ 3 ▁years ▁and ▁up ▁to ▁ 7 0 ▁percent ▁rec ur ▁within ▁ 5 ▁years . ▁Di ab etic ▁foot ▁disease ▁is ▁the ▁leading ▁cause ▁of ▁non - tra um atic ▁lower ▁lim b ▁am put ations . ▁ ▁Research ▁ ▁St em ▁cell ▁ther apy ▁may ▁represent ▁a ▁treatment ▁for ▁prom oting ▁he aling ▁of ▁di ab etic ▁foot ▁ul cers . ▁Di ab etic ▁foot ▁ul cers ▁develop ▁their ▁own , ▁distinct ive ▁micro bi ota . ▁Investig ations ▁into ▁character izing ▁and ▁ident ifying ▁the ▁ph y la , ▁gener a ▁and ▁species ▁of ▁non path ogen ic ▁b acter ia ▁or ▁other ▁micro organ isms ▁popul ating ▁these ▁ul cers ▁may ▁help ▁identify ▁one ▁group ▁of ▁micro bi ota ▁that ▁prom otes ▁he aling . ▁ ▁The ▁recent ▁adv ances ▁in ▁ep igen etic ▁modifications , ▁with ▁special ▁focus ▁on ▁aber rant ▁macro ph age ▁polar isation ▁is ▁giving ▁increasing ▁ev id ences ▁that ▁ep igen etic ▁modifications ▁might ▁play ▁a ▁vital ▁role ▁in ▁changing ▁the ▁treatment ▁of ▁di ab etic ▁foot ▁ul cer ▁in ▁the ▁near ▁future . ▁ ▁References ▁ ▁External ▁links ▁▁ ▁Category : Di ab etes ▁Category : Foot ▁dise ases <0x0A> </s> ▁Av on ▁Valley ▁is ▁a ▁national