TR . ▁ ▁A ▁number ▁of ▁trans cription ▁factors ▁ ▁such ▁as ▁FO X P 1 , ▁SO X 5 , ▁SO X 6 , ▁SO X 4 , ▁and ▁M Z F 1 ▁are ▁likely ▁to ▁bind ▁with ▁the ▁prom oter , ▁often ▁acting ▁to ▁down reg ulate ▁trans cription . ▁When ▁regarding ▁the ▁expression ▁of ▁other ▁gen es , ▁these ▁trans cription ▁factors ▁typically ▁play ▁a ▁role ▁in ▁the ▁development ▁of ▁various ▁t issues ▁such ▁as ▁the ▁heart , ▁lung , ▁and ▁also ▁take ▁part ▁in ▁the ▁different iation ▁of ▁early ▁emb ry onic ▁cells , ▁and ▁red ▁blood ▁cells . ▁ ▁Trans cription al ▁reg ulation ▁ ▁It ▁is ▁sus pected ▁that ▁the ▁m ature ▁m R NA ▁of ▁C 1 9 orf 6 7 ▁forms ▁a ▁stem ▁loop ▁on ▁the ▁ 3 ' ▁U TR ▁that ▁sp ans ▁from ▁ 1 , 2 9 6 bp ▁to ▁ 1 , 3 5 0 bp ▁of ▁the ▁trans cript . ▁ ▁T issue ▁expression ▁ ▁In ▁humans , ▁UP F 0 5 7 5 ▁protein ▁C 1 9 orf 6 7 ▁is ▁highly ▁expressed ▁in ▁the ▁test is ▁and ▁breast ▁t issue , ▁although ▁it ▁is ▁also ▁expressed ▁at ▁low ▁levels ▁ ▁in ▁the ▁st om ach , ▁c ere br al ▁cor tex , ▁thy roid ▁g land , ▁and ▁sal iv ary ▁g land . ▁ ▁The ▁protein ▁product ▁is ▁less ▁abund ant ▁than ▁most ▁of ▁the ▁human ▁prote ome ▁in ▁many ▁t issues . ▁ ▁Hom ology