▁used ▁can ▁also ▁be ▁reduced ▁by ▁using ▁m ice ▁subject ▁to ▁str ic ter ▁quality ▁control ▁than ▁mon keys . ▁ ▁" Rep lacement " ▁refers ▁to ▁a ▁" switch ▁to ▁research ▁not ▁using ▁animals " ▁but ▁a ▁" switch ▁to ▁a ▁method ▁not ▁using ▁ph y log en et ically ▁higher ▁animals ▁such ▁as ▁mon keys " ▁is ▁a ▁method ▁of ▁natural ▁protection . ▁ ▁Using ▁this ▁alternative ▁we ▁succeeded ▁in ▁reducing ▁the ▁z oon otic ▁ris ks ▁for ▁investig ators ▁( Re fin ement ). ▁ ▁Central ▁Institute ▁for ▁Ex perimental ▁Anim als ▁( CI E A ) ▁Dr . ▁Nom ura ▁is ▁currently ▁Director ▁of ▁the ▁Central ▁Institute ▁for ▁Ex perimental ▁Anim als , ▁Japan , ▁that ▁he ▁founded ▁in ▁ 1 9 5 2 , ▁to ▁improve ▁the ▁level ▁of ▁medical ▁research . ▁ ▁Biography ▁▁ 2 0 0 6 – present : ▁Central ▁Institute ▁for ▁Ex perimental ▁Anim als ▁( CI E A ) ▁Chair man ▁of ▁the ▁Board ▁▁▁ 1 9 9 9 – present : ▁Council or , ▁The ▁Japan ▁Society ▁for ▁Organ ▁Pres ervation ▁and ▁Medical ▁Bi ology ▁▁ 1 9 9 7 - 2 0 0 3 : ▁Chair man , ▁International ▁Council ▁for ▁Labor atory ▁Animal ▁Science ▁( IC L AS ) ▁Mon itor ing ▁& ▁Reference ▁Centre ▁Program ▁▁▁ 1 9 9 7 : ▁Japanese ▁Association ▁for ▁Labor atory ▁Animal ▁Science ▁( J AL AS ) ▁Honor ary ▁Member ▁▁ 1 9 9 5 : ▁President , ▁J AL AS ▁ 4