acc ines . ▁The ▁al umin um ▁in ▁v acc ines ▁sim ul ates ▁or ▁causes ▁small ▁amounts ▁of ▁t issue ▁damage , ▁driving ▁the ▁body ▁to ▁respond ▁more ▁power fully ▁to ▁what ▁it ▁sees ▁as ▁a ▁serious ▁in fection ▁and ▁prom oting ▁the ▁development ▁of ▁a ▁last ing ▁imm une ▁response . ▁In ▁some ▁cases ▁these ▁comp ounds ▁have ▁been ▁associated ▁with ▁red ness , ▁it ch ing , ▁and ▁low - grade ▁fe ver , ▁but ▁the ▁use ▁of ▁al umin um ▁in ▁v acc ines ▁has ▁not ▁been ▁associated ▁with ▁serious ▁ad verse ▁events . ▁In ▁some ▁cases , ▁al umin um - cont aining ▁v acc ines ▁are ▁associated ▁with ▁macro ph ag ic ▁my of as ci itis ▁( MM F ), ▁local ized ▁micro scop ic ▁les ions ▁containing ▁al umin um ▁sal ts ▁that ▁persist ▁for ▁up ▁to ▁ 8 ▁years . ▁However , ▁recent ▁case - control led ▁studies ▁have ▁found ▁no ▁specific ▁clin ical ▁sympt oms ▁in ▁individuals ▁with ▁bi ops ies ▁showing ▁MM F , ▁and ▁there ▁is ▁no ▁evidence ▁that ▁al umin um - cont aining ▁v acc ines ▁are ▁a ▁serious ▁health ▁risk ▁or ▁justify ▁changes ▁to ▁imm un ization ▁practice . ▁Inf ants ▁are ▁exposed ▁to ▁greater ▁quantities ▁of ▁al umin um ▁in ▁daily ▁life ▁in ▁breast mil k ▁and ▁infant ▁formula ▁than ▁in ▁v acc ines . ▁In ▁general , ▁people ▁are ▁exposed ▁to ▁low ▁levels ▁of ▁naturally ▁occurr ing ▁al umin um ▁in ▁nearly ▁all ▁food s ▁and