▁knock down ▁of ▁the ▁protein ▁dis rupted ▁retro grade ▁flow ▁of ▁the ▁K DE L ▁re ceptor ▁from ▁the ▁Gol gi ▁to ▁the ▁ER . ▁Furthermore , ▁S cy l 1 ▁local ization ▁in ▁rat ▁hi pp oc amp al ▁neur ons ▁also ▁demonstr ates ▁a ▁similar ▁relationship ▁to ▁CO PI . ▁ ▁C lin ical ▁significance ▁ ▁Mut ations ▁in ▁S cy l 1 ▁are ▁the ▁gen etic ▁defect ▁resulting ▁in ▁the ▁phen ot ype ▁of ▁mus cle ▁def ic ient ▁m ice ▁( m df ▁m ice ) ▁that ▁suffer ▁from ▁a ▁progress ive ▁ne uro de gener ation ▁of ▁the ▁c ere bell um ▁and ▁lower ▁motor ▁neur ons . ▁M df ▁m ice ▁model ▁human ▁spin oc ere bell ar ▁at ax ia ▁type ▁dis orders . ▁ ▁References ▁ ▁Further ▁reading <0x0A> </s> ▁Frederick ▁L . ▁Lewis ▁( born ▁July ▁ 1 , ▁ 1 9 4 3 ) ▁is ▁a ▁retired ▁American ▁basketball ▁player . ▁ ▁He ▁played ▁profession ally ▁in ▁the ▁National ▁Basketball ▁Association ▁( N BA ) ▁and ▁American ▁Basketball ▁Association ▁( AB A ). ▁ ▁He ▁is ▁the ▁only ▁player ▁to ▁start ▁his ▁career ▁in ▁the ▁NBA , ▁and ▁play ▁all ▁ 9 ▁full ▁A BA ▁seasons ▁( 1 9 6 7 - 1 9 7 6 ) ▁until ▁the ▁NBA / AB A ▁mer ger , ▁then ▁sign ▁back ▁with ▁the ▁NBA . ▁ ▁Born ▁in ▁Hun ting ton , ▁West ▁Virginia , ▁Lewis ▁was ▁a ▁fund ament ally ▁sound ▁ 6 '