▁ren al ▁disease / hem od ial ysis , ▁and ▁mechanical ▁ir rit ation ▁or ▁prolong ed ▁bed ▁rest . ▁ ▁Some ▁cases ▁of ▁Gro ver ' s ▁disease ▁have ▁been ▁associated ▁with ▁medic ations ▁such ▁as ▁sul f ado x ine - py rim eth am ine , ▁rib av ir in , ▁cet ux im ab , ▁and ▁inter le uk in - 4 ▁[ 1 , 8 - 1 5 ]. ▁One ▁series ▁of ▁ 3 0 0 ▁patients ▁with ▁Gro ver ' s ▁disease ▁reported ▁an ▁association ▁with ▁other ▁co ex isting ▁der mat oses ▁including ▁at op ic ▁der mat itis , ▁contact ▁der mat itis , ▁and ▁x eros is ▁cut is . ▁Finally , ▁smaller ▁series ▁have ▁detailed ▁an ▁association ▁with ▁py oder ma ▁gang ren os um , ▁b acter ial ▁and ▁vir al ▁in fe ctions , ▁and ▁occasionally , ▁m align an cies . ▁ ▁Di agn osis ▁Gro ver ' s ▁may ▁be ▁sus pected ▁by ▁its ▁appearance , ▁but ▁since ▁it ▁has ▁such ▁a ▁characteristic ▁appearance ▁under ▁the ▁mic ros cope ▁a ▁sh ave ▁skin ▁or ▁p unch ▁bi ops y ▁is ▁often ▁performed . ▁ ▁Tre at ment ▁S we ating ▁causes ▁les ions ▁to ▁form , ▁but ▁les ions ▁ag gra v ated ▁by ▁swe at ▁usually ▁return ▁to ▁" normal " ▁fairly ▁quickly av oid ing ▁swe at ▁is ▁not ▁a ▁reason ▁to ▁avoid ▁exercise . ▁Minor ▁out break s ▁can ▁be ▁controlled ▁with ▁pres cription ▁strength ▁top