con du ction ▁mechanism ▁of ▁this ▁channel , ▁by ▁quant ifying ▁the ▁pro ton ▁transfer ▁rates ▁and ▁equilib ria ▁between ▁water ▁and ▁the ▁pro ton - select ive ▁hist id ine ▁resid ue . ▁She ▁showed ▁that ▁the ▁ant iv iral ▁drug ▁am ant ad ine ▁in hib its ▁pro ton ▁condu ction ▁by ▁direct ▁occ l usion ▁of ▁the ▁channel ▁p ore . ▁She ▁determined ▁the ▁ch ol ester ol - binding ▁structure ▁of ▁the ▁M 2 ▁protein , ▁which ▁sh eds ▁light ▁on ▁how ▁ch ol ester ol ▁medi ates ▁M 2 ' s ▁memb rane ▁sc ission ▁function . ▁ ▁Other ▁memb rane ▁prote ins ▁that ▁Hong ' s ▁group ▁has ▁studied ▁include ▁ β - h air pin ▁ant im icro b ial ▁pe pt ides , ▁channel - form ing ▁col ic ins , ▁and ▁vir al ▁fusion ▁prote ins . ▁She ▁determined ▁the ▁structure ▁of ▁the ▁memb rane ▁tor oid al ▁por es ▁formed ▁by ▁the ▁ant im icro b ial ▁pe pt ide ▁prote gr in - 1 , ▁which ▁explained ▁the ▁memb rane - dis rupt ive ▁mechanism ▁of ▁this ▁pe pt ide . ▁She ▁showed ▁that ▁the ▁transm emb rane ▁domain ▁of ▁vir al ▁fusion ▁prote ins ▁can ▁be ▁struct ur ally ▁pl astic , ▁and ▁the ▁ β - sheet ▁con formation ▁can ▁correlate ▁with ▁the ▁generation ▁of ▁memb rane ▁curv ature ▁and ▁memb rane ▁de h yd r ation , ▁which ▁are ▁necessary ▁for ▁virus - cell ▁fusion . ▁ ▁Hong ▁has