▁treatment ▁option . ▁ ▁Gilbert ' s ▁synd rome , ▁a ▁gen etic ▁dis order ▁of ▁bil ir ub in ▁met abol ism ▁found ▁in ▁a ▁small ▁percent ▁of ▁the ▁population , ▁can ▁cause ▁m ild ▁j au nd ice . ▁ ▁Cir r hos is ▁is ▁the ▁formation ▁of ▁f ibr ous ▁t issue ▁( f ib ros is ) ▁in ▁the ▁place ▁of ▁li ver ▁cells ▁that ▁have ▁died ▁due ▁to ▁a ▁variety ▁of ▁causes , ▁including ▁vir al ▁he pat itis , ▁alco hol ▁over consum ption , ▁and ▁other ▁forms ▁of ▁li ver ▁to x icity . ▁Cir r hos is ▁causes ▁chron ic ▁li ver ▁failure . ▁ ▁Primary ▁li ver ▁cancer ▁most ▁commonly ▁manifest s ▁as ▁he pat oc ell ular ▁car cin oma ▁or ▁ch ol ang i oc arc in oma ; ▁r ar er ▁forms ▁include ▁ang ios ar com a ▁and ▁hem ang ios ar com a ▁of ▁the ▁li ver . ▁( Many ▁li ver ▁m align an cies ▁are ▁secondary ▁les ions ▁that ▁have ▁met ast as ized ▁from ▁primary ▁can cers ▁in ▁the ▁g astro int est inal ▁tract ▁and ▁other ▁org ans , ▁such ▁as ▁the ▁kid ne ys , ▁l ungs .) ▁ ▁Primary ▁b ili ary ▁cir r hos is ▁is ▁a ▁serious ▁auto imm une ▁disease ▁of ▁the ▁b ile ▁cap ill aries . ▁ ▁Primary ▁s cl eros ing ▁ch ol ang itis ▁is ▁a ▁serious ▁chron ic ▁infl am mat ory ▁disease ▁of ▁the