, ▁where ▁they ▁become ▁concentr ated ▁in ▁the ▁ac inal ▁cells . ▁A ▁small ▁number ▁of ▁sp or oz o ites ▁are ▁introduced ▁into ▁the ▁sal iv ary ▁du ct ▁and ▁inject ed ▁into ▁the ▁ven ules ▁of ▁the ▁bit ten ▁human . ▁This ▁initi ates ▁the ▁cycle ▁in ▁the ▁human ▁li ver . ▁ ▁Mor ph ology ▁The ▁ring ▁stages ▁that ▁are ▁formed ▁by ▁the ▁invasion ▁of ▁m ero zo ites ▁released ▁by ▁ru pt uring ▁li ver ▁stage ▁sch izont s ▁are ▁the ▁first ▁stages ▁that ▁appear ▁in ▁the ▁blood . ▁The ▁ring ▁stages ▁grow ▁slowly ▁but ▁soon ▁fill ▁one - four th ▁to ▁one - third ▁of ▁the ▁par as it ized ▁cell . ▁P ig ment ▁increases ▁rapidly ▁and ▁the ▁half - g rown ▁par as ite ▁may ▁have ▁from ▁ 3 0 ▁to ▁ 5 0 ▁jet - black ▁gran ules . ▁The ▁par as ite ▁changes ▁various ▁shapes ▁as ▁it ▁grows ▁and ▁st ret ches ▁across ▁the ▁host ▁cell ▁to ▁form ▁the ▁band ▁form . ▁ ▁Labor atory ▁consider ations ▁P . ▁viv ax ▁and ▁P . ▁ov ale ▁sitting ▁in ▁ED TA ▁for ▁more ▁than ▁ 3 0 ▁minutes ▁before ▁the ▁blood ▁film ▁is ▁made ▁will ▁look ▁very ▁similar ▁in ▁appearance ▁to ▁P . ▁mal aria e , ▁which ▁is ▁an ▁important ▁reason ▁to ▁warn ▁the ▁labor atory ▁immediately ▁when ▁the ▁blood ▁sample ▁is ▁drawn ▁so ▁they ▁can ▁process ▁the ▁sample ▁as ▁soon ▁as ▁it ▁arriv es . ▁ ▁Micro scop ically , ▁the ▁par as