ical ▁treat ments ▁have ▁not ▁been ▁well ▁studied ▁but ▁may ▁be ▁benef icial . ▁ ▁Research ▁Active ▁clin ical ▁tri als ▁investig ating ▁n ail ▁ps or ias is : ▁ ▁Ph ase ▁IV ▁▁ ▁Effect s ▁of ▁Et an er cept . ▁ ▁Effect s ▁of ▁Gol imum ab . ▁ ▁Ph ase ▁II ▁▁ ▁D ose ▁response ▁and ▁safety ▁of ▁top ical ▁M eth ot re x ate . ▁ ▁See ▁also ▁Ps or ias is ▁N ail ▁disease ▁ ▁References ▁ ▁External ▁links ▁▁▁ ▁N ail ▁ps or ias is ▁at ▁Med s cape ▁▁▁▁ ▁Category : Cond itions ▁of ▁the ▁skin ▁append ages <0x0A> </s> ▁B irmingham ▁city ▁centre , ▁also ▁known ▁as ▁Central ▁B irmingham ▁and ▁often ▁known ▁locally ▁as ▁town , ▁is ▁the ▁central ▁business ▁district ▁of ▁B irmingham , ▁England . ▁Following ▁the ▁removal ▁of ▁the ▁Inner ▁Ring ▁Road , ▁the ▁city ▁centre ▁is ▁now ▁defined ▁as ▁being ▁the ▁area ▁within ▁the ▁Middle ▁Ring ▁Road . ▁The ▁city ▁centre ▁is ▁under going ▁massive ▁re development ▁with ▁the ▁Big ▁City ▁Plan , ▁which ▁means ▁there ▁are ▁now ▁nine ▁emer ging ▁districts ▁and ▁the ▁city ▁centre ▁is ▁approximately ▁five ▁times ▁bigger . ▁ ▁District s ▁City ▁Centre ▁Core ▁West side ▁East side ▁South side ▁Jew ell ery ▁Qu arter ▁Gun ▁Qu arter ▁High gate ▁Lady wood ▁Dig b eth ▁ ▁History ▁ ▁Following ▁the ▁removal ▁of ▁the ▁Inner ▁Ring ▁Road , ▁which ▁acted ▁as ▁a ▁" con crete ▁col lar " ▁" under ▁which ▁ped est ri ans