▁( V es icles ): ▁Change ▁in ▁Mechan ism ▁Produ ced ▁by ▁As ym met rical ▁Distribution ▁of ▁S od ium ▁and ▁Pot ass ium ▁I ons ,” ▁published ▁two ▁years ▁later , ▁H ess ▁expl ored ▁the ▁bi phas ic ▁flux ▁and ▁des ens it ization ▁of ▁the ▁ac et yl ch oline ▁re ceptor ▁in ▁connection ▁with ▁mic ros ac ▁function . ▁ ▁He ▁continued ▁studying ▁the ▁relationship ▁between ▁the ▁ac et yl ch oline ▁re ceptor ▁and ▁flux ▁in ▁his ▁article ▁published ▁in ▁ 1 9 8 0 : ▁“ M ole cular ▁Mechan ism ▁of ▁Ac et yl ch oline ▁Re ceptor - Control led ▁I on ▁Trans location ▁Ac ross ▁Cell ▁M emb ran es .”   ▁He ▁studied ▁these ▁channels ▁in ▁the ▁cells ▁of ▁the ▁electric ▁org ans ▁of ▁the ▁Elect roph orus ▁electric us ▁and ▁the ▁Tor ped o ▁cal iforn ica .   ▁H ess ▁used ▁car b am yl ch oline , ▁a ▁chemical ▁analog ▁of ▁ac et yl ch oline , ▁to ▁conduct ▁these ▁studies .   ▁This ▁study ▁mapped ▁how ▁these ▁re cept ors ▁worked , ▁their ▁lig and ▁binding ▁sites , ▁and ▁how ▁they ▁respond ed ▁to ▁variation ▁in ▁ac et yl ch oline / car b am yl ch oline ▁concentr ations ▁by ▁conduct ing ▁studies ▁into ▁the ▁channel ▁k inet ics .   ▁He ▁looked ▁at ▁the ▁way ▁that ▁these ▁concentr ations ▁affected ▁the ▁active ▁and ▁in active ▁states ▁of ▁the ▁channel , ▁and ▁determined ▁that ▁the ▁equilibrium ▁position