▁or ▁treat ments ▁can ▁be ▁tested ▁against ▁these ▁mouse ▁models . ▁ ▁A ▁mouse ▁has ▁been ▁gen et ically ▁engine ered ▁to ▁have ▁increased ▁mus cle ▁growth ▁and ▁strength ▁by ▁over express ing ▁the ▁ins ul in - like ▁growth ▁factor ▁I ▁( IG F - I ) ▁in ▁differenti ated ▁mus cle ▁fib ers . ▁Another ▁mouse ▁has ▁had ▁a ▁gene ▁alter ed ▁that ▁is ▁involved ▁in ▁gl uc ose ▁met abol ism ▁and ▁runs ▁faster , ▁lives ▁longer , ▁is ▁more ▁sex ually ▁active ▁and ▁e ats ▁more ▁without ▁getting ▁f atter ▁than ▁the ▁average ▁mouse ▁( see ▁Met abol ic ▁super m ice ). ▁ ▁Great ▁care ▁should ▁be ▁taken ▁when ▁dec iding ▁how ▁to ▁use ▁gen et ically ▁modified ▁m ice ▁in ▁research . ▁Even ▁basic ▁issues ▁like ▁choosing ▁the ▁correct ▁" w ild - type " ▁control ▁mouse ▁to ▁use ▁for ▁comparison ▁are ▁sometimes ▁over look ed . ▁ ▁References ▁ ▁External ▁links ▁Mouse ▁Gen ome ▁In format ics ▁( in format ics . jax . org ) ▁M amm al ian ▁Gen et ics ▁Unit ▁Har well : ▁Mouse ▁models ▁for ▁human ▁disease ▁ ▁Category : Mouse ▁gen et ics ▁Category : 1 9 7 4 ▁in ▁bi ote chn ology ▁Category : Gen etic ▁engineering <0x0A> </s> ▁Spirit ▁of ▁Man ila ▁Airlines ▁Corporation , ▁operating ▁as ▁Spirit ▁of ▁Man ila ▁Airlines , ▁was ▁a ▁low - cost ▁air line ▁based ▁in ▁Ro x as ▁Sea ▁Front ▁Garden ▁in ▁Pas ay ▁City , ▁Philippines . ▁Its ▁main