, ▁which ▁is ▁one ▁of ▁the ▁most ▁dep riv ed ▁seats ▁in ▁the ▁entire ▁United ▁Kingdom - ▁an ▁estimated ▁ 4 0 % ▁of ▁adult s ▁in ▁the ▁constitu ency ▁smoke . ▁In ▁comparison , ▁the ▁highest ▁sm oking ▁pre val ence ▁in ▁England ▁is ▁in ▁King ston ▁upon ▁H ull ▁at ▁ 2 6 . 1 %. ▁ ▁The ▁UK ▁sm oking ▁rate ▁had ▁fallen ▁to ▁ 1 4 . 4 % ▁in ▁ 2 0 1 8 . ▁ 2 5 ▁- ▁ 3 4 ▁year ▁old s ▁still ▁have ▁the ▁highest ▁sm oking ▁rate , ▁with ▁approximately ▁ 1 ▁in ▁ 5 ▁people ▁within ▁this ▁age ▁range ▁sm oking ▁equ ating ▁to ▁around ▁ 1 . 4 ▁million ▁sm ok ers ▁in ▁the ▁UK . ▁ ▁Health ▁issues ▁It ▁has ▁been ▁estimated ▁by ▁Can cer ▁Research ▁UK ▁that ▁sm oking ▁is ▁the ▁single ▁greatest ▁cause ▁of ▁prevent able ▁ill ness ▁and ▁early ▁death , ▁with ▁around ▁ 1 0 7 , 0 0 0 ▁people ▁dying ▁in ▁ 2 0 0 7 ▁from ▁sm oking - related ▁dise ases ▁including ▁can cers ▁in ▁the ▁UK . ▁Ar ound ▁ 8 6 % ▁of ▁lung ▁cancer ▁death s ▁in ▁the ▁UK ▁are ▁caused ▁by ▁to b acco ▁sm oking ▁and ▁overall ▁to b acco ▁sm oking ▁is ▁estimated ▁to ▁be ▁responsible ▁for ▁more ▁than ▁a ▁quarter ▁of ▁cancer ▁death s ▁in ▁the ▁UK , ▁around ▁ 4 3 , 0 0 0 ▁death s ▁in ▁ 2 0 0 7 .