osis ▁and ▁treatment ▁of ▁de ment ia ▁synd rom es , ▁the ▁path oph ys i ology ▁of ▁alco hol ▁add iction ▁and ▁the ▁path oph ys i ology ▁of ▁major ▁de press ive ▁dis order . ▁He ▁has ▁author ed ▁or ▁co - author ed ▁more ▁than ▁ 4 0 0 ▁Journal ▁articles . ▁K orn h uber ▁described ▁novel ▁mole cular ▁mechan isms ▁of ▁approved ▁psych otrop ic ▁dru gs , ▁namely ▁that ▁mem antine , ▁am ant ad ine , ▁bud ip ine ▁and ▁or phen adr ine ▁act ▁as ▁low - aff inity ▁N MD A - re ceptor ▁ant agon ists . ▁The ▁data ▁obtained ▁with ▁mem antine ▁formed ▁an ▁important ▁basis ▁for ▁its ▁world wide ▁appro val ▁as ▁an ▁ant ide ment ive ▁drug . ▁K orn h uber ▁developed ▁the ▁ph arm ac ok in etic ▁hypothesis ▁explaining ▁the ▁delayed ▁th era pe ut ic ▁effects ▁of ▁ant ide press ant ▁dru gs . ▁Furthermore , ▁he ▁found ▁that ▁ant ide press ant ▁dru gs ▁like ▁am it ri pty line ▁and ▁flu ox et ine ▁medi ate ▁their ▁effects ▁on ▁ne uro gen esis ▁and ▁behavior ▁by ▁lower ing ▁cer am ide ▁abund ance ▁in ▁the ▁brain . ▁Among ▁his ▁co auth ors ▁has ▁been ▁Peter ▁R ieder er . ▁ ▁Hon ors ▁▁ ▁Scient ific ▁Award ▁of ▁the ▁German ▁Society ▁for ▁Psych iat ry ▁( 1 9 9 0 ) ▁ ▁Organ on - A ward ▁of ▁the ▁German ▁Society ▁for ▁Bi ological ▁Psych