▁has ▁been ▁increasing ▁every ▁year . ▁ ▁There ▁has ▁been ▁extensive ▁use ▁of ▁ant ib iot ics ▁in ▁animal ▁husband ry . ▁In ▁the ▁United ▁States , ▁the ▁question ▁of ▁emer gence ▁of ▁ant ib i otic - res istant ▁b acter ial ▁stra ins ▁due ▁to ▁use ▁of ▁ant ib iot ics ▁in ▁liv est ock ▁was ▁raised ▁by ▁the ▁US ▁Food ▁and ▁D rug ▁Administration ▁( F DA ) ▁in ▁ 1 9 7 7 . ▁In ▁March ▁ 2 0 1 2 , ▁the ▁United ▁States ▁District ▁Court ▁for ▁the ▁Southern ▁District ▁of ▁New ▁York , ▁r uling ▁in ▁an ▁action ▁brought ▁by ▁the ▁Natural ▁Resources ▁Def ense ▁Council ▁and ▁others , ▁ordered ▁the ▁F DA ▁to ▁re voke ▁appro val s ▁for ▁the ▁use ▁of ▁ant ib iot ics ▁in ▁liv est ock , ▁which ▁viol ated ▁F DA ▁reg ulations . ▁ ▁History ▁ ▁Before ▁the ▁early ▁ 2 0 th ▁century , ▁treat ments ▁for ▁in fe ctions ▁were ▁based ▁primarily ▁on ▁medic inal ▁fol kl ore . ▁Mi xt ures ▁with ▁ant im icro b ial ▁properties ▁that ▁were ▁used ▁in ▁treat ments ▁of ▁in fe ctions ▁were ▁described ▁over ▁ 2 , 0 0 0 ▁years ▁ago . ▁Many ▁ancient ▁cult ures , ▁including ▁the ▁ancient ▁Egypt ians ▁and ▁ancient ▁Gree ks , ▁used ▁spe cially ▁selected ▁m old ▁and ▁plant ▁materials ▁and ▁extract s ▁to ▁treat ▁in fe ctions . ▁ ▁The ▁use ▁of ▁ant ib iot ics ▁in ▁modern ▁medicine ▁began ▁with ▁the