▁about ▁£ 0 . 8 9 ▁as ▁of ▁ 2 0 1 9 . ▁In ▁the ▁United ▁States ▁the ▁wh oles ale ▁cost ▁of ▁this ▁amount ▁is ▁about ▁US $ 1 2 8 . 0 0 . ▁In ▁ 2 0 1 7 , ▁it ▁was ▁the ▁ 1 4 4 th ▁most ▁commonly ▁pres cribed ▁medic ation ▁in ▁the ▁United ▁States , ▁with ▁more ▁than ▁four ▁million ▁pres cri ptions . ▁ ▁Medical ▁uses ▁It ▁is ▁used ▁to ▁treat ▁high ▁blood ▁pressure ▁and ▁heart ▁failure . ▁ ▁A CE ▁in hib itors , ▁ang iot ens in ▁II ▁re ceptor ▁ant agon ists , ▁calci um - channel ▁block ers , ▁and ▁th ia z ide ▁di ure t ics ▁are ▁generally ▁preferred ▁over ▁beta ▁block ers ▁for ▁the ▁treatment ▁of ▁high ▁blood ▁pressure . ▁ ▁Cont ra ind ic ations ▁▁ ▁Se vere ▁br ady card ia ▁ ▁Heart ▁block ▁greater ▁than ▁first ▁degree ▁ ▁Pat ients ▁with ▁card i ogen ic ▁shock ▁ ▁De comp ens ated ▁card iac ▁failure ▁ ▁S ick ▁sin us ▁synd rome ▁( unless ▁a ▁permanent ▁pac em aker ▁is ▁in ▁place ) ▁ ▁Pat ients ▁with ▁severe ▁he p atic ▁imp air ment ▁( Child - P ugh ▁class ▁B ) ▁ ▁Pat ients ▁who ▁are ▁hyp ers ens itive ▁to ▁any ▁component ▁of ▁this ▁product . ▁ ▁Ad verse ▁re actions ▁▁▁ ▁Head ache ▁ ▁Par est hes ia ▁ ▁D izz iness ▁ ▁S low ▁heart ▁rate ▁ ▁Ph arm ac ology