▁st ria ▁v asc ular is ▁and ▁the ▁hair ▁cells , ▁both ▁essential ▁to ▁sound ▁trans du ction , ▁make ▁use ▁of ▁ion ▁p umps ▁to ▁reg ulate ▁the ▁concentration ▁of ▁ ions ▁including ▁K + , ▁Na + , ▁and ▁Ca 2 + ▁using ▁ATP . ▁Without ▁sufficient ▁levels ▁of ▁ATP , ▁these ▁concentration ▁grad ients ▁are ▁not ▁maintained ▁and ▁this ▁can ▁lead ▁to ▁cell ▁death ▁in ▁both ▁the ▁st ria ▁v asc ular is ▁and ▁the ▁hair ▁cells , ▁causing ▁hearing ▁loss . ▁ ▁Table ▁ 1 : ▁Met abol ically ▁active ▁org ans ▁that ▁can ▁be ▁affected ▁by ▁the ▁ 3 2 4 3 A > G ▁mit och ond rial ▁point ▁mut ation ▁and ▁the ▁associated ▁comp lication : ▁ ▁Di agn osis ▁ ▁Tre at ment ▁ ▁Initial ▁ ▁Initial ly , ▁the ▁person ▁is ▁treated ▁by ▁di et ary ▁changes ▁and ▁hyp og ly ca em ic ▁agents . ▁This ▁does ▁not ▁last ▁long ▁before ▁the ▁person ▁has ▁to ▁be ▁started ▁on ▁ins ul in ▁( with in ▁ 2 ▁years ▁of ▁diagn osis ). ▁ ▁See ▁also ▁ ▁De af ness ▁ ▁Di ab etes ▁ ▁References ▁ ▁External ▁links ▁▁ ▁Category : Di ab etes ▁Category : De af ness ▁Category : M ito ch ond rial ▁dise ases <0x0A> </s> ▁Su z anne ▁Hel ena ▁Johann a ▁Harm es ▁( born ▁January ▁ 1 0 , ▁ 1 9 8 6 ▁in ▁Zo et erme er ) ▁is ▁a ▁Dutch ▁g ymn ast .