▁percentage ▁of ▁the ▁target ▁family . ▁ ▁Str ategy ▁▁ ▁Chem ogen om ics ▁integr ates ▁target ▁and ▁drug ▁discovery ▁by ▁using ▁active ▁comp ounds , ▁which ▁function ▁as ▁lig ands , ▁as ▁prob es ▁to ▁character ize ▁prote ome ▁functions . ▁ ▁The ▁interaction ▁between ▁a ▁small ▁comp ound ▁and ▁a ▁protein ▁indu ces ▁a ▁phen ot ype . ▁ ▁Once ▁the ▁phen ot ype ▁is ▁character ized , ▁we ▁could ▁associate ▁a ▁protein ▁to ▁a ▁mole cular ▁event . ▁ ▁Comp ared ▁with ▁gen et ics , ▁chem ogen om ics ▁techniques ▁are ▁able ▁to ▁modify ▁the ▁function ▁of ▁a ▁protein ▁rather ▁than ▁the ▁gene . ▁ ▁Also , ▁chem ogen om ics ▁is ▁able ▁to ▁observe ▁the ▁interaction ▁as ▁well ▁as ▁revers ibility ▁in ▁real - time . ▁ ▁For ▁example , ▁the ▁modification ▁of ▁a ▁phen ot ype ▁can ▁be ▁observed ▁only ▁after ▁addition ▁of ▁a ▁specific ▁comp ound ▁and ▁can ▁be ▁interrupted ▁after ▁its ▁withdraw al ▁from ▁the ▁medium . ▁ ▁Currently , ▁there ▁are ▁two ▁experimental ▁chem ogen omic ▁approaches : ▁forward ▁( class ical ) ▁chem ogen om ics ▁and ▁reverse ▁chem ogen om ics . ▁For ward ▁chem ogen om ics ▁attempt ▁to ▁identify ▁drug ▁targets ▁by ▁searching ▁for ▁mole cules ▁which ▁give ▁a ▁certain ▁phen ot ype ▁on ▁cells ▁or ▁animals , ▁while ▁reverse ▁chem ogen om ics ▁aim ▁to ▁validate ▁phen ot ypes ▁by ▁searching ▁for ▁mole cules ▁that ▁interact ▁specifically ▁with ▁a ▁given ▁protein . ▁ ▁Both ▁of ▁these ▁approaches ▁require ▁a