la cy l - Co A ▁rac em ase , ▁which ▁is ▁a ▁recently ▁described ▁marker ▁for ▁pro state ▁cancer . ▁ ▁As ▁opposed ▁to ▁the ▁foc al ▁type ▁of ▁ne uro end ocr ine ▁different iation ▁seen ▁in ▁pro static ▁ad en oc arc in oma , ▁small ▁cell ▁car cin oma ▁of ▁the ▁pro state , ▁in ▁turn , ▁exhib it ▁a ▁universal ▁type ▁in ▁that ▁virt ually ▁all ▁the ▁constitu ent ▁tum or ▁cells ▁display ▁ne uro end ocr ine ▁features . ▁Im mun oh ist och em ically , ▁pro static ▁small ▁cell ▁car cin oma ▁are ▁positive ▁for ▁thy roid ▁trans cription ▁factor ▁ 1 ▁( T TF - 1 ), ▁CD 5 6 , ▁chrom og ran in ▁A , ▁syn apt oph ys in , ▁neur on - specific ▁en ol ase , ▁cal cit on in ▁and ▁bomb es in / g astr in - re le asing ▁pe pt ide , ▁while ▁lack ing , ▁or ▁rarely ▁and ▁weak ly ▁express ing , ▁and ro gen ▁re ceptor ▁and ▁pro state - specific ▁ant igen . ▁ ▁It ▁is ▁commonly ▁believed ▁that ▁pro static ▁ad en oc arc in oma ▁exhib iting ▁significant ▁ne uro end ocr ine ▁different iation ▁is ▁less ▁differenti ated , ▁more ▁ag gress ive ▁and ▁h orm one ▁ther apy - res istant . ▁ ▁References ▁ ▁Category : Ne uro end ocr in ology <0x0A> </s> ▁Pet roph ila ▁l ules alis ▁is ▁a ▁moth ▁in ▁the ▁family