agu ais , ▁and ▁Jean ne ▁de ▁Bour bon , ▁Duch ess ▁of ▁Bour bon ▁( 1 4 6 5 – 1 5 1 1 ). ▁She ▁was ▁a ▁pen ult imate ▁representative ▁of ▁the ▁senior ▁branch ▁of ▁the ▁house ▁de ▁La ▁Tour ▁d ' A u ver g ne . ▁Made le ine ▁is ▁best ▁known ▁for ▁being ▁the ▁mother ▁of ▁Catherine ▁de ' ▁Med ici , ▁the ▁future ▁Queen ▁of ▁France . ▁ ▁Biography ▁ ▁Mar riage ▁negoti ations ▁As ▁part ▁of ▁his ▁efforts ▁to ▁gain ▁power ▁in ▁Italy , ▁Francis ▁I ▁of ▁France ▁turned ▁to ▁making ▁certain ▁strateg ic ▁al li ances . ▁On ▁ 8 ▁December ▁ 1 5 1 5 , ▁he ▁and ▁Pope ▁Leo ▁X ▁met ▁and ▁signed ▁an ▁agreement ▁of ▁friendship , ▁in ▁which ▁Francis ▁agreed ▁to ▁ensure ▁the ▁V at ican ' s ▁authority ▁over ▁the ▁Catholic ▁Church ▁in ▁France , ▁and ▁Leo ▁promised ▁to ▁support ▁Francis ' ▁claim ▁to ▁the ▁throne ▁of ▁Nap les . ▁This ▁agreement , ▁like ▁most ▁others ▁of ▁the ▁time , ▁was ▁c ement ed ▁with ▁a ▁marriage ▁al liance . ▁Leo ' s ▁nep hew ▁Lorenzo ▁II ▁de ' ▁Med ici ▁had ▁just ▁become ▁the ▁leader ▁of ▁the ▁Flor ent ine ▁republic ▁in ▁ 1 5 1 6 . ▁Francis ▁wrote ▁to ▁con gr at ulate ▁him ▁by ▁stating , ▁" I ▁intend ▁to ▁help ▁you ▁with ▁all ▁my ▁power . ▁I ▁also ▁wish ▁to ▁marry ▁you ▁off ▁to ▁some ▁beautiful ▁and ▁good ▁lady ▁of ▁noble ▁birth ▁and ▁of