▁to ▁perform ▁activities ▁of ▁daily ▁living ▁in ▁individuals ▁with ▁Al z heimer ' s ▁disease . ▁One ▁review ▁suggested ▁that , ▁based ▁upon ▁trans gen ic ▁mouse ▁models , ▁the ▁cogn itive ▁effects ▁of ▁exercise ▁on ▁Al z heimer ' s ▁disease ▁may ▁result ▁from ▁a ▁reduction ▁in ▁the ▁quantity ▁of ▁am y lo id ▁pla que . ▁ ▁The ▁Ca er ph illy ▁Pro s pective ▁study ▁followed ▁ 2 , 3 7 5   male ▁subjects ▁over ▁ 3 0   year s ▁and ▁exam ined ▁the ▁association ▁between ▁health y ▁l ifest yles ▁and ▁de ment ia , ▁among ▁other ▁factors . ▁Anal ys es ▁of ▁the ▁Ca er ph illy ▁study ▁data ▁have ▁found ▁that ▁exercise ▁is ▁associated ▁with ▁a ▁lower ▁inc idence ▁of ▁de ment ia ▁and ▁a ▁reduction ▁in ▁cogn itive ▁imp air ment . ▁A ▁subsequent ▁system atic ▁review ▁of ▁longitud inal ▁studies ▁also ▁found ▁higher ▁levels ▁of ▁physical ▁activity ▁to ▁be ▁associated ▁with ▁a ▁reduction ▁in ▁the ▁risk ▁of ▁de ment ia ▁and ▁cogn itive ▁decl ine ; ▁this ▁review ▁further ▁assert ed ▁that ▁increased ▁physical ▁activity ▁appears ▁to ▁be ▁caus ally ▁related ▁with ▁these ▁reduced ▁ris ks . ▁ ▁Park inson ' s ▁disease ▁ ▁Park inson ' s ▁disease ▁( PD ) ▁is ▁a ▁movement ▁dis order ▁that ▁produces ▁sympt oms ▁such ▁as ▁br ady k ines ia , ▁rig id ity , ▁sh aking , ▁and ▁imp a ired ▁g ait . ▁ ▁A ▁review ▁by ▁K ram er ▁and ▁colle agues