▁trans gl ut amin ase ▁in ▁int est inal ▁m uc us . ▁Om ega - 5 - g li ad ins , ▁a ▁comp ound ▁found ▁in ▁whe at ▁that ▁is ▁commonly ▁associated ▁with ▁F DE IA , ▁is ▁cross - link ed ▁by ▁trans gl ut amin ase , ▁resulting ▁in ▁large ▁form ations ▁of ▁pe pt ide ▁aggreg ates , ▁and ▁leads ▁to ▁an ▁increase ▁in ▁Ig E ▁binding . ▁ ▁Blood ▁flow ▁red ist ribution ▁ ▁During ▁exercise , ▁blood ▁is ▁red ist ributed ▁from ▁in active ▁to ▁active ▁t issues ▁in ▁the ▁body . ▁It ▁has ▁been ▁suggested ▁that ▁food - sens it ised ▁imm une ▁cells ▁associated ▁with ▁the ▁gut ▁do ▁not ▁e voke ▁an ap hy la ctic ▁sympt oms ▁so ▁long ▁as ▁they ▁remain ▁in ▁a ▁local ▁circul ation . ▁The ▁theory ▁suggests ▁that ▁if ▁these ▁sens it ised ▁cells ▁are ▁shift ed ▁to ▁the ▁skin ▁and / or ▁ske let al ▁mus cles ▁following ▁exercise , ▁F DE IA ▁sympt oms ▁are ▁likely ▁to ▁occur . ▁A ▁ 2 0 1 0 ▁study ▁demonstrated ▁that ▁food ▁all erg ens ▁were ▁well ▁toler ated ▁by ▁m ast ▁cells ▁in ▁the ▁int est inal ▁tract , ▁and ▁thus ▁no ▁sympt oms ▁occurred ▁at ▁rest . ▁M ast ▁cells ▁are ▁struct ur ally ▁different ▁in ▁the ▁gut ▁than ▁those ▁found ▁in ▁the ▁skin ▁or ▁ske let al ▁mus cles , ▁and ▁thus ▁could ▁be ▁induced ▁by ▁food ▁all erg ens . ▁ ▁Tre at ment ▁ ▁If