ics , ▁ret inal ▁imag ing , ▁and ▁national ▁defense ▁purposes . ▁ ▁Most ▁recently , ▁Boston ▁Mic rom ach ines ▁has ▁developed ▁an ▁Ada pt ive ▁Opt ics ▁Sc anning ▁Las er ▁O ph th al mos cope ▁for ▁high - resol ution ▁in ▁v ivo ▁imag ing ▁in ▁the ▁human ▁ret ina ▁for ▁use ▁in ▁pre - cl in ical ▁studies . ▁The ▁instrument ▁is ▁currently ▁in ▁use ▁in ▁the ▁Fe in berg ▁School ▁of ▁Medicine ▁and ▁the ▁Jos lin ▁Di ab etes ▁Center . ▁Cap abilities ▁include ▁quant itative ▁measures ▁of ▁cone ▁phys i ology , ▁detection ▁of ▁micro ane ur ys ms ▁and ▁small ▁vessel ▁blood ▁flow ▁profil ing . ▁ ▁Their ▁products ▁are ▁often ▁custom ized ▁for ▁specific ▁applications . ▁ ▁App lications ▁ ▁Astronom y ▁Boston ▁Mic rom ach ines ▁develop s ▁de form able ▁mirror s ▁for ▁teles cop es ▁to ▁correct ▁for ▁atmos pher ic ▁disturb ance . ▁Project s ▁currently ▁using ▁Boston ▁Mic rom ach ines ' ▁mirror ▁technology ▁include ▁the ▁Vi LL a GE s ▁Project ▁at ▁the ▁L ick ▁Observ atory ▁as ▁well ▁as ▁the ▁Gem ini ▁Planet ▁Im ager ▁in ▁Chile . ▁ ▁Bi ological ▁imag ing ▁Through ▁the ▁use ▁of ▁adapt ive ▁opt ics , ▁de form able ▁mirror s ▁can ▁be ▁used ▁to ▁enh ance ▁Conf ocal ▁techniques ▁such ▁as ▁two - ph ot on ▁exc itation ▁flu ores c ence ▁( 2 PE F ), ▁second - ▁and / or ▁third - H arm onic ▁Generation ▁( SH