▁Zur ich ▁R uz ick a ▁Prize ▁in ▁ 2 0 0 1 . ▁She ▁joined ▁É cole ▁Poly te chni que ▁F éd éra le ▁de ▁La us anne ▁as ▁an ▁associate ▁professor ▁in ▁ 2 0 0 2 ▁and ▁was ▁made ▁full ▁professor ▁in ▁ 2 0 0 9 . ▁In ▁ 2 0 0 5 ▁she ▁was ▁the ▁first ▁woman ▁to ▁be ▁awarded ▁the ▁World ▁Association ▁of ▁The oret ical ▁and ▁Comput ational ▁Chem ists ▁Di rac ▁Medal . ▁ ▁Rö eth lis berger ▁works ▁on ▁density ▁functional ▁theory , ▁extending ▁the ▁Car - Par rin ello ▁method ▁to ▁include ▁Q M / MM ▁simulations ▁in ▁a ▁code ▁called ▁CP MD . ▁ ▁Q M / MM ▁systems ▁treat ▁the ▁electron ically ▁active ▁part ▁of ▁a ▁mole cular ▁structure ▁as ▁a ▁quantum ▁mechanical ▁system , ▁whereas ▁the ▁rest ▁of ▁the ▁mole c ule ▁is ▁treated ▁class ically ▁using ▁mole cular ▁mechan ics . ▁She ▁uses ▁her ▁hy brid ▁Car – Par rin ello ▁systems ▁to ▁study ▁en zym atic ▁re actions ▁to ▁design ▁bi om im etic ▁comp ounds . ▁Rö eth lis berger ▁ ▁has ▁also ▁expanded ▁Q M / MM ▁to ▁include ▁ground ▁to ▁excited ▁state ▁trans itions , ▁making ▁it ▁possible ▁to ▁predict ▁photo indu ced ▁charge ▁separation ▁and ▁electron ▁transfer . ▁She ▁also ▁works ▁on ▁ab ▁init io ▁simulations ▁of ▁bi ological ▁systems , ▁and ▁has ▁added ▁the ▁Van ▁der ▁Wa als ▁interactions ▁of ▁mac rom ole cules ▁to ▁density ▁functional ▁theory . ▁She ▁has ▁used