known . ▁The ▁cons ensus ▁is ▁that ▁DA O ▁is ▁produced ▁and ▁is ▁active ▁in ▁gli al ▁cells , ▁most ▁specifically ▁in ▁c ere bell ar ▁type - 1 ▁and ▁type - 2 ▁ast ro cy tes , ▁and ▁the ▁D - ser ine ▁am ino ▁acid ▁that ▁is ▁produced ▁by ▁DA O ▁in ▁these ▁cells ▁has ▁been ▁shown ▁to ▁increase ▁syn apt ic ▁N MD A ▁re ceptor ▁activity . ▁ ▁Imp act ▁on ▁sch iz op hren ia ▁ ▁There ▁is ▁evidence ▁to ▁show ▁that ▁sch iz op hren ia , ▁as ▁a ▁neural ▁phenomen on , ▁is ▁caused ▁by ▁the ▁in app ropri ate ▁activity ▁of ▁N MD A ▁re cept ors ▁and ▁the ▁related ▁increase ▁in ▁gl ut am ate ▁activity ▁associated ▁with ▁N MD A ▁re cept ors . ▁▁ ▁It ▁has ▁been ▁shown ▁that ▁increased ▁DA O ▁activity ▁produces ▁more ▁D - ser ine , ▁which ▁in ▁turn ▁has ▁been ▁shown ▁to ▁increase ▁N MD A ▁activity ▁in ▁the ▁hypoth al am us . ▁A ▁study ▁confirmed ▁the ▁increased ▁N MD A ▁activity ▁and ▁showed ▁increased ▁DA O ▁activity ▁in ▁the ▁c ere bell um ▁of ▁sch iz op hren ia ▁subjects . ▁The ▁gen etic ▁background ▁of ▁DA O ▁invol vement ▁in ▁sch iz op hren ia ▁is ▁highly ▁deb ated , ▁and ▁no ▁comp uls atory ▁evidence ▁has ▁been ▁found ▁for ▁DA O ▁gen es ▁being ▁strongly ▁linked ▁to ▁sch iz op hren ia . ▁Although , ▁the ▁G 7 2 ▁gene , ▁which ▁reported