▁dest abil ize . ▁Oct av ius ▁ref uses ▁to ▁shut ▁down ▁the ▁re actor , ▁which ▁goes ▁critical ▁– ▁killing ▁his ▁wife ▁and ▁burning ▁the ▁in hib itor ▁chip ▁blocking ▁the ▁arms ▁from ▁his ▁nerv ous ▁system . ▁Peter , ▁as ▁Spider - Man , ▁sh uts ▁the ▁experiment ▁down , ▁destroy ing ▁it ▁in ▁the ▁process . ▁ ▁At ▁a ▁hospital , ▁do ctors ▁prepare ▁to ▁surg ically ▁remove ▁Oct av ius ' ▁har ness . ▁Without ▁the ▁in hib itor ▁chip , ▁the ▁now ▁sent ient ▁arms ▁defend ▁themselves ▁by ▁killing ▁the ▁do ctors . ▁Upon ▁reg aining ▁conscious ness ▁and ▁seeing ▁the ▁car n age , ▁Oct av ius ▁esc apes ▁and ▁takes ▁refuge ▁at ▁a ▁har bor . ▁Be coming ▁increasing ly ▁influenced ▁by ▁the ▁arms ' ▁A I , ▁he ▁dec ides ▁to ▁re - try ▁his ▁experiment . ▁He ▁ro bs ▁a ▁bank ▁to ▁fund ▁a ▁second ▁experiment . ▁Peter ▁and ▁May ▁coinc ident ally ▁are ▁there , ▁and ▁Oct av ius ▁takes ▁May ▁host age . ▁Peter ▁res c ues ▁her , ▁but ▁Oct av ius ▁fle es ▁with ▁the ▁st olen ▁money . ▁The ▁Daily ▁Bug le ▁subsequently ▁dub s ▁the ▁scient ist ▁Doctor ▁Oct opus . ▁ ▁Mary ▁Jane ▁becomes ▁engaged ▁to ▁astr onaut ▁John ▁James on , ▁the ▁son ▁of ▁Bug le ▁editor ▁J . ▁Jon ah ▁James on . ▁Peter ▁suff ers ▁an ▁emot ional ▁break down ▁over ▁his ▁in ability ▁to ▁balance ▁his ▁life ▁and ▁los es ▁his ▁powers .