li xim ab ▁ ▁Gol imum ab ▁ ▁Low ▁do se ▁m eth ot re x ate ▁ ▁In tr ales ional ▁cort ic ost ero id ▁injection ▁ ▁Rel ative ▁effect iveness ▁of ▁treat ments ▁Av ailable ▁studies ▁lack ▁sufficient ▁power ▁to ▁ext rap olate ▁a ▁standard ized ▁th era pe ut ic ▁reg imen . ▁As ▁of ▁April ▁ 2 0 0 9 , ▁an ▁assess ment ▁of ▁the ▁evidence ▁for ▁the ▁effic acy ▁and ▁safety ▁of ▁the ▁treat ments ▁for ▁n ail ▁ps or ias is ▁is ▁in ▁progress . ▁ ▁Inf li xim ab ▁appears ▁to ▁be ▁the ▁most ▁effective ▁treatment ▁for ▁n ail ▁ps or ias is ▁to ▁date . ▁ ▁Results ▁from ▁low - d ose ▁ac it ret in ▁ther apy ▁show ▁N AP SI ▁score ▁redu ctions ▁compar able ▁with ▁those ▁studies ▁evalu ating ▁bi olog ic ▁dru gs ▁for ▁n ail ▁ps or ias is ▁and ▁suggest ▁that ▁low - d ose ▁system ic ▁ac it ret in ▁should ▁be ▁considered ▁in ▁the ▁treatment ▁of ▁n ail ▁ps or ias is . ▁ ▁A ▁ 2 0 1 3 ▁meta - analysis ▁showed ▁improvement ▁of ▁n ail ▁ps or ias is ▁with ▁inf li xim ab , ▁gol imum ab , ▁super f icial ▁radi other apy , ▁electron ▁beam , ▁and ▁gr enz ▁ray s ▁compared ▁to ▁place bo . ▁Although ▁system ic ▁ther ap ies ▁have ▁been ▁shown ▁to ▁be ▁benef icial , ▁they ▁may ▁have ▁serious ▁ad verse ▁effects . ▁Top