P . R . D . ▁is ▁a ▁well ▁known ▁and ▁respect ed ▁organization ▁that ▁has ▁excellent ▁relations ▁with ▁most ▁international ▁govern ments ▁and ▁United ▁States ▁government ▁ag encies , ▁with ▁the ▁exceptions ▁of ▁China ▁and ▁the ▁C IA . ▁ ▁The ▁Pl ague ▁of ▁Fro gs ▁Cy cle ▁The ▁Bureau ▁was ▁the ▁United ▁States ' ▁only ▁defense ▁against ▁an ▁on s la ug ht ▁of ▁f rog ▁cre atures ▁( origin ally ▁featured ▁in ▁Se ed ▁of ▁Dest ruction ). ▁Though ▁the ▁" f ro gs " ▁began ▁operating ▁on ▁the ▁East ▁Coast , ▁they ▁spread ▁west ▁on ▁both ▁sides ▁of ▁the ▁US - Can ada ▁border . ▁To ▁cut ▁costs , ▁the ▁Bureau ▁moved ▁from ▁its ▁traditional ▁headquarters ▁in ▁Connecticut ▁to ▁an ▁abandoned ▁research ▁facility ▁in ▁Colorado . ▁This ▁facility ▁was ▁last ▁used ▁to ▁house ▁Naz i ▁scient ists ▁who ▁defect ed ▁to ▁America ▁after ▁World ▁War ▁II . ▁As ▁such , ▁the ▁facility ▁contains ▁vast ▁quantities ▁of ▁secret ▁files ▁that ▁the ▁B . P . R . D . ▁has ▁yet ▁to ▁explore . ▁ ▁The ▁f rog ▁mon ster ▁invasion ▁reached ▁its ▁peak ▁during ▁the ▁events ▁of ▁The ▁Black ▁Fl ame ▁during ▁which ▁a ▁Ne o - N azi ▁mad man ▁adopted ▁the ▁persona ▁of ▁the ▁World ▁War ▁II ▁era ▁super villa in ▁the ▁Black ▁Fl ame ▁and ▁ins inu ated ▁himself ▁as ▁the ▁leader ▁of ▁the ▁fro gs . ▁T ogether ▁they ▁raised ▁the ▁gig antic ▁Kath a - H em ▁( one ▁of ▁the ▁Og dru ▁Hem