▁include ▁breast ▁tend ern ess ▁and ▁en larg ement , ▁femin ization , ▁sexual ▁d ys function , ▁and ▁hot ▁flash es . ▁Con vers ely , ▁the ▁medic ation ▁has ▁fewer ▁side ▁effects ▁and ▁is ▁better - tol er ated ▁in ▁women . ▁Di arr he a ▁and ▁elev ated ▁li ver ▁en zym es ▁can ▁occur ▁in ▁both ▁sex es . ▁R are ly , ▁fl ut am ide ▁can ▁cause ▁li ver ▁damage , ▁lung ▁disease , ▁sens itivity ▁to ▁light , ▁elev ated ▁m eth em og lo bin , ▁elev ated ▁sul f hem og lo bin , ▁and ▁def ic ient ▁neut roph ils . ▁N umer ous ▁cases ▁of ▁li ver ▁failure ▁and ▁death ▁have ▁been ▁reported , ▁which ▁has ▁limited ▁the ▁use ▁of ▁fl ut am ide . ▁ ▁Fl ut am ide ▁acts ▁as ▁a ▁select ive ▁ant agon ist ▁of ▁the ▁and ro gen ▁re ceptor ▁( AR ), ▁compet ing ▁with ▁and rog ens ▁like ▁test oster one ▁and ▁di h ydro test oster one ▁( D HT ) ▁for ▁binding ▁to ▁AR s ▁in ▁t issues ▁like ▁the ▁pro state ▁g land . ▁By ▁doing ▁so , ▁it ▁prevents ▁their ▁effects ▁and ▁stops ▁them ▁from ▁stim ulating ▁pro state ▁cancer ▁cells ▁to ▁grow . ▁Fl ut am ide ▁is ▁a ▁prod rug ▁to ▁a ▁more ▁active ▁form . ▁Fl ut am ide ▁and ▁its ▁active ▁form ▁stay ▁in ▁the ▁body ▁for ▁a ▁relatively ▁short ▁time , ▁which ▁makes ▁it ▁necessary ▁to