: Place ▁of ▁birth ▁unknown <0x0A> </s> ▁H eter ogeneous ▁nuclear ▁rib on uc le op rote in ▁H 3 ▁is ▁a ▁protein ▁that ▁in ▁humans ▁is ▁encoded ▁by ▁the ▁H NR N PH 3 ▁gene . ▁ ▁This ▁gene ▁belongs ▁to ▁the ▁sub family ▁of ▁u bi quit ously ▁expressed ▁heter ogeneous ▁nuclear ▁rib on uc le op rote ins ▁( hn R NP s ). ▁The ▁h n R NP s ▁are ▁R NA ▁binding ▁prote ins ▁and ▁they ▁complex ▁with ▁heter ogeneous ▁nuclear ▁R NA ▁( hn R NA ). ▁These ▁prote ins ▁are ▁associated ▁with ▁pre - m R N As ▁in ▁the ▁nucle us ▁and ▁appear ▁to ▁influence ▁pre - m R NA ▁processing ▁and ▁other ▁aspects ▁of ▁m R NA ▁met abol ism ▁and ▁transport . ▁While ▁all ▁of ▁the ▁h n R NP s ▁are ▁present ▁in ▁the ▁nucle us , ▁some ▁seem ▁to ▁sh utt le ▁between ▁the ▁nucle us ▁and ▁the ▁cy top las m . ▁The ▁h n R NP ▁prote ins ▁have ▁distinct ▁nucle ic ▁acid ▁binding ▁properties . ▁The ▁protein ▁encoded ▁by ▁this ▁gene ▁has ▁two ▁repe ats ▁of ▁quasi - R R M ▁domains ▁that ▁bind ▁to ▁R N As . ▁It ▁is ▁local ized ▁in ▁nuclear ▁bodies ▁of ▁the ▁nucle us . ▁This ▁protein ▁is ▁involved ▁in ▁the ▁sp lic ing ▁process ▁and ▁it ▁also ▁particip ates ▁in ▁early ▁heat ▁shock - indu ced ▁sp lic ing ▁arrest ▁by ▁trans ient ly ▁leaving ▁the ▁h n R NP ▁complex