▁into ▁a ▁small ▁pocket ▁located ▁under ▁the ▁ab dom inal ▁skin ▁and ▁connected ▁to ▁the ▁stim ulation ▁device ▁( IP G ). ▁Min im ally - in vas ive ▁procedures ▁have ▁been ▁shown ▁to ▁dram atically ▁reduce ▁he aling ▁time ▁as ▁well ▁as ▁reduce ▁procedure ▁risk . ▁ ▁The ▁first ▁clin ical ▁study ▁using ▁End o St im ▁technology ▁was ▁published ▁in ▁ 2 0 1 0 , ▁showing ▁that ▁in ▁patients ▁with ▁G ER D , ▁elect rical ▁stim ulation ▁ther apy ▁significantly ▁and ▁consist ently ▁increased ▁L ES ▁pressure . ▁▁ ▁An ▁open - label ▁trial ▁conducted ▁in ▁Chile ▁showed ▁the ▁procedure ▁showed ▁“ sign ific ant ▁and ▁sust ained ▁improvement ▁in ▁G ER D ▁sympt oms , ▁es oph age al ▁p H , ▁and ▁reduction ▁in ▁pro ton - p ump ▁in hib itor ▁( P PI ) ▁usage ▁without ▁any ▁side ▁effects ” ▁in ▁patients . ▁ ▁Us age ▁▁ ▁End ost im ▁ther apy ▁is ▁currently ▁not ▁approved ▁by ▁the ▁U . S . ▁Food ▁and ▁D rug ▁Administration ▁( F DA ) ▁though ▁clin ical ▁tri als ▁to ▁purs ue ▁appro val ▁are ▁on . ▁The ▁procedure , ▁however , ▁received ▁the ▁CE ▁mark ▁allowing ▁impl ants ▁in ▁Europe . ▁End ost im ▁is ▁carried ▁out ▁in ▁Argentina , ▁Chile , ▁Colombia , ▁Brazil , ▁Hong ▁Kong , ▁India , ▁Den mark , ▁Germany , ▁Netherlands ▁and ▁Switzerland . ▁ ▁References ▁▁ ▁Category : Dig est ive ▁system ▁procedures <0x0A> </s> ▁H ang ▁S eng ▁Global