– T aw il ▁synd rome , ▁Wa arden burg ▁synd rome ▁and ▁cri ▁du ▁chat ▁synd rome , ▁along ▁with ▁pie b ald ism , ▁prominent ▁inner ▁third ▁of ▁the ▁e y eb rows , ▁ir ises ▁of ▁different ▁color , ▁sp ond y lo ep i phy se al ▁d ys pl asia , ▁m uc opol ys ac char ide ▁met abol ism ▁dis orders ▁( Mor qu io ▁synd rome ▁and ▁Hur ler ' s ▁synd rome ), ▁de af ness ▁and ▁also ▁in ▁hypoth y roid ism . ▁ ▁Some ▁links ▁have ▁been ▁found ▁between ▁hy pert elor ism ▁and ▁attention ▁def ic it / hyper activity ▁dis order . ▁ ▁Emb ry ology ▁Because ▁hy pert elor ism ▁is ▁an ▁an atomic ▁condition ▁associated ▁with ▁a ▁heter ogeneous ▁group ▁of ▁con gen ital ▁dis orders , ▁it ▁is ▁believed ▁that ▁the ▁underlying ▁mechanism ▁of ▁hy pert elor ism ▁is ▁also ▁heter ogeneous . ▁The ories ▁include ▁too ▁early ▁o ss ification ▁of ▁the ▁lower ▁wings ▁of ▁the ▁s phen oid , ▁an ▁increased ▁space ▁between ▁the ▁orb ita , ▁due ▁to ▁increasing ▁width ▁of ▁the ▁eth m oid ▁sin uses , ▁field ▁defect s ▁during ▁the ▁development , ▁a ▁nas al ▁caps ule ▁that ▁fails ▁to ▁form , ▁leading ▁to ▁a ▁failure ▁in ▁normal ▁med ial ▁orb ital ▁migration ▁and ▁also ▁a ▁disturb ance ▁in ▁the ▁formation ▁of ▁the ▁c ran ial ▁base , ▁which ▁can ▁be ▁seen ▁in ▁synd rom es ▁like ▁A pert ▁and ▁Cr