▁been ▁used ▁in ▁the ▁study ▁of ▁US P 1 1 ▁function . ▁A ▁conditional ▁knock out ▁mouse ▁line ▁called ▁U sp 1 1 tm 1 ( K O MP ) W t si ▁was ▁generated ▁at ▁the ▁Well come ▁Trust ▁S anger ▁Institute . ▁Male ▁and ▁female ▁animals ▁under w ent ▁a ▁standard ized ▁phen ot yp ic ▁screen ▁to ▁determine ▁the ▁effects ▁of ▁delet ion . ▁Add itional ▁screens ▁performed : ▁In - depth ▁imm un ological ▁phen ot yp ing ▁ ▁References ▁ ▁Further ▁reading <0x0A> </s> ▁Fred ▁Bar r att ▁( 1 2 ▁April ▁ 1 8 9 4 ▁– ▁ 2 9 ▁January ▁ 1 9 4 7 ) ▁played ▁first - class ▁cr icket ▁for ▁Not ting ham shire ▁from ▁ 1 9 1 4 ▁to ▁ 1 9 3 1 ▁and ▁represented ▁England ▁in ▁five ▁Test ▁matches , ▁one ▁in ▁the ▁home ▁series ▁against ▁South ▁Africa ▁in ▁ 1 9 2 9 ▁and ▁four ▁on ▁the ▁inaug ural ▁Test ▁series ▁against ▁New ▁Zealand ▁in ▁the ▁ 1 9 2 9 - 3 0 ▁season . ▁He ▁was ▁born ▁in ▁An nes ley , ▁Not ting ham shire ▁and ▁died ▁at ▁Not ting ham ▁General ▁Hospital , ▁Not ting ham . ▁ ▁From ▁a ▁min ing ▁background , ▁Bar r att ▁was ▁a ▁right - arm ▁fast ▁bow ler ▁who , ▁according ▁to ▁Wis den , ▁combined ▁" swer ve ▁with ▁his ▁pace ". ▁He ▁was ▁also ▁a ▁right - hand ed ▁lower - order ▁b ats man