▁in ▁ 1 ▁in ▁ 5 0 0 ▁people . ▁Some ▁of ▁the ▁more ▁frequently ▁seen ▁forms ▁of ▁P ID ▁include ▁common ▁variable ▁imm un ode fic iency , ▁severe ▁combined ▁imm un ode fic iency , ▁X - link ed ▁ag amm ag lob ul in emia , ▁W isk ott – A ld rich ▁synd rome , ▁Di Ge orge ▁synd rome , ▁at ax ia – tel ang ie ct asia , ▁ ▁Tre at ment ▁The ▁treatment ▁of ▁primary ▁imm un ode fic ien cies ▁depends ▁for em ost ▁on ▁the ▁nature ▁of ▁the ▁ab normal ity . ▁Som atic ▁treatment ▁of ▁primarily ▁gen etic ▁defect s ▁is ▁in ▁its ▁inf ancy . ▁ ▁Most ▁treatment ▁is ▁therefore ▁pass ive ▁and ▁pal li ative , ▁and ▁falls ▁into ▁two ▁modal ities : ▁man aging ▁in fe ctions ▁and ▁boost ing ▁the ▁imm une ▁system . ▁ ▁Red u ction ▁of ▁expos ure ▁to ▁path og ens ▁may ▁be ▁recommended , ▁and ▁in ▁many ▁situations ▁pro phy la ctic ▁ant ib iot ics ▁or ▁ant iv ir als ▁may ▁be ▁ad vised . ▁ ▁In ▁the ▁case ▁of ▁hum oral ▁imm une ▁def ic iency , ▁imm un og lob ul in ▁replacement ▁ther apy ▁in ▁the ▁form ▁of ▁int ra ven ous ▁imm un og lob ul in ▁( IV IG ) ▁or ▁sub cut aneous ▁imm un og lob ul in ▁( SC IG ) ▁may ▁be ▁available . ▁ ▁In ▁cases ▁of ▁auto imm une ▁dis orders