▁by ▁bow ing ▁of ▁the ▁long ▁b ones ▁and ▁many ▁other ▁ske let al ▁and ▁ex tras ke let al ▁features . ▁It ▁is ▁frequently ▁le th al ▁in ▁the ▁ne on atal ▁period ▁due ▁to ▁resp ir atory ▁ins u ffic iency , ▁but ▁the ▁sever ity ▁of ▁the ▁disease ▁is ▁variable , ▁and ▁some ▁patients ▁surv ive ▁into ▁ad ul th ood . ▁The ▁name ▁is ▁derived ▁from ▁the ▁Greek ▁roots ▁campo ▁( or ▁cam pto ), ▁meaning ▁bent , ▁and ▁mel ia , ▁meaning ▁lim b . ▁An ▁unusual ▁aspect ▁of ▁the ▁disease ▁is ▁that ▁up ▁to ▁two - third s ▁of ▁affected ▁ 4 6 , XY ▁gen ot yp ic ▁males ▁display ▁a ▁range ▁of ▁Dis orders ▁of ▁Sex ual ▁Development ▁( D SD ) ▁and ▁gen ital ▁ambigu ities ▁or ▁may ▁even ▁develop ▁as ▁normal ▁phen ot yp ic ▁females ▁as ▁in ▁complete ▁ 4 6 ▁X Y ▁sex ▁revers al . ▁An ▁at yp ical ▁form ▁of ▁the ▁disease ▁with ▁absence ▁of ▁bow ed ▁lim bs ▁is ▁called , ▁pro sa ically , ▁ac amp om el ic ▁camp om el ic ▁d ys pl asia ▁( AC D ) ▁and ▁is ▁found ▁in ▁about ▁ 1 0 % ▁of ▁patients , ▁particularly ▁those ▁surv iving ▁the ▁ne on atal ▁period . ▁ ▁Sign s ▁and ▁sympt oms ▁▁ ▁While ▁the ▁definit ive ▁presentation ▁of ▁the ▁disease ▁is ▁a ▁patient ▁having ▁bow ed ▁lower ▁lim bs ▁and ▁sex ▁revers al ▁in ▁ 4 6 , XY