ib i otic ▁protein ▁bar n ase ▁( a ▁rib on uc lease ), ▁alpha ▁am yl ase ▁used ▁in ▁st arch ▁hydro ly s is , ▁the ▁prote ase ▁sub til is in ▁used ▁with ▁d eter g ents , ▁and ▁the ▁B am H 1 ▁restriction ▁en zym e ▁used ▁in ▁DNA ▁research . ▁ ▁A ▁portion ▁of ▁the ▁Bac ill us ▁th uring i ensis ▁gen ome ▁was ▁incorpor ated ▁into ▁corn ▁( and ▁cot ton ) ▁cro ps . ▁The ▁resulting ▁G MO s ▁are ▁ ▁resist ant ▁to ▁some ▁insect ▁p ests . ▁Bac ill us ▁species ▁continue ▁to ▁be ▁dominant ▁b acter ial ▁work h ors es ▁in ▁micro b ial ▁fer ment ations . ▁Bac ill us ▁sub til is ▁( nat to ) ▁is ▁the ▁key ▁micro b ial ▁particip ant ▁in ▁the ▁on going ▁production ▁of ▁the ▁so ya - based ▁traditional ▁nat to ▁fer ment ation , ▁and ▁some ▁Bac ill us ▁species ▁are ▁on ▁the ▁Food ▁and ▁D rug ▁Administration ' s ▁GR AS ▁( gener ally ▁regarded ▁as ▁safe ) ▁list . ▁The ▁capacity ▁of ▁selected ▁Bac ill us ▁stra ins ▁to ▁produce ▁and ▁se crete ▁large ▁quantities ▁( 2 0 - 2 5 ▁g / L ) ▁of ▁ext rac ell ular ▁en zym es ▁has ▁placed ▁them ▁among ▁the ▁most ▁important ▁industrial ▁en zym e ▁produ cers . ▁The ▁ability ▁of ▁different ▁species ▁to ▁fer ment ▁in ▁the ▁acid , ▁neutral , ▁and ▁al kal ine ▁p H ▁ranges