rier ▁protein ▁( AC P ). ▁ ▁Poly ket ide ▁b ios yn thesis ▁MC AT ▁is ▁also ▁involved ▁in ▁b acter ial ▁poly ket ide ▁b ios yn thesis . ▁ ▁The ▁en zym e ▁MC AT ▁together ▁with ▁an ▁a cy l ▁car rier ▁protein ▁( AC P ), ▁and ▁a ▁poly ket ide ▁synth ase ▁( P KS ) ▁and ▁chain - length ▁factor ▁heter od imer , ▁ ▁constit utes ▁the ▁minimal ▁P KS ▁of ▁type ▁II ▁poly ket ides . ▁ ▁Reg ulation ▁Mal ony l - Co A ▁is ▁a ▁highly ▁reg ulated ▁mole c ule ▁in ▁fat ty ▁acid ▁synth esis ; ▁as ▁such , ▁it ▁in hib its ▁the ▁rate - lim iting ▁step ▁in ▁beta - ox id ation ▁of ▁fat ty ▁ac ids . ▁Mal ony l - Co A ▁in hib its ▁fat ty ▁ac ids ▁from ▁associ ating ▁with ▁car nit ine ▁by ▁reg ulating ▁the ▁en zym e ▁car nit ine ▁a cy l trans fer ase , ▁thereby ▁prevent ing ▁them ▁from ▁entering ▁the ▁mit och ond ria , ▁where ▁fat ty ▁acid ▁ox id ation ▁and ▁de grad ation ▁occur . ▁ ▁See ▁also ▁Mal ony l - Co A ▁dec ar box yl ase ▁Mal ony l - Co A ▁dec ar box yl ase ▁def ic iency ▁ ▁References ▁ ▁External ▁links ▁ ▁Hope ▁for ▁new ▁way ▁to ▁beat ▁ob es ity ▁ ▁Category : Met abol ism ▁Category : Th io esters ▁of ▁co enz