▁| ▁South ▁Carolina ( 2 ) ▁| ▁V ac ant ▁| ▁Senator ▁Daniel ▁E . ▁H ug er ▁res igned ▁in ▁previous ▁con gress . Success or ▁elected ▁November ▁ 2 6 , ▁ 1 8 4 5 . ▁| ▁ ▁| ▁John ▁C . ▁Cal h oun ▁( D ) ▁| ▁Elect ed ▁November ▁ 2 6 , ▁ 1 8 4 5 ▁ ▁| - ▁| ▁Virginia ( 1 ) ▁| ▁V ac ant ▁| ▁Fail ure ▁to ▁elect ▁| ▁ ▁| ▁Isaac ▁S . ▁Pen ny back er ▁( D ) ▁| ▁Elect ed ▁December ▁ 3 , ▁ 1 8 4 5 ▁ ▁| - ▁| ▁Mississippi ( 2 ) ▁| ▁ ▁| ▁Robert ▁J . ▁Walker ▁( D ) ▁| ▁Res igned ▁March ▁ 5 , ▁ 1 8 4 5 , ▁after ▁being ▁appointed ▁U . S . ▁Secretary ▁of ▁the ▁Tre as ury . Success or ▁appointed ▁November ▁ 3 , ▁ 1 8 4 5 . App o inte e ▁was ▁later ▁elected ▁on ▁an ▁unknown ▁date . ▁| ▁ ▁| ▁Joseph ▁W . ▁Chal mers ▁( D ) ▁| ▁App oint ed ▁November ▁ 3 , ▁ 1 8 4 5 ▁ ▁| - ▁| ▁Pennsylvania ( 3 ) ▁| ▁ ▁| ▁James ▁Buch an an ▁( D ) ▁| ▁Res igned ▁March ▁ 5 , ▁ 1 8 4 5 , ▁after ▁being ▁appointed ▁U . S . ▁Secretary ▁of ▁State ▁| ▁ ▁| ▁Simon ▁Camer on ▁( D ) ▁| ▁Elect ed