▁in ▁the ▁p yr rol id ine ▁ring . ▁N umer ous ▁other ▁total ▁synth eses ▁util ize ▁the ▁St ille ▁reaction , ▁including ▁those ▁of ▁ox az ol om yc in , ▁l ank ac id in ▁C , ▁on am ide ▁A , ▁cal y cul in ▁A , ▁le pic id in ▁A , ▁rip ost atin ▁A , ▁and ▁luc il act a ene . ▁ ▁The ▁image ▁below ▁displays ▁the ▁final ▁natural ▁product , ▁the ▁organ oh al ide ▁( blue ), ▁the ▁organ ost ann ane ▁( red ), ▁and ▁the ▁bond ▁being ▁formed ▁( green ▁and ▁circ led ). ▁ ▁From ▁these ▁examples , ▁it ▁is ▁clear ▁that ▁the ▁St ille ▁reaction ▁can ▁be ▁used ▁both ▁at ▁the ▁early ▁stages ▁of ▁the ▁synth esis ▁( ox az ol om yc in ▁and ▁cal y cul in ▁A ), ▁at ▁the ▁end ▁of ▁a ▁conver gent ▁route ▁( on am ide ▁A , ▁l ank ac id in ▁C , ▁rip ost atin ▁A ), ▁or ▁in ▁the ▁middle ▁( le pic id in ▁A ▁and ▁luc il act a ene ). ▁ ▁The ▁synth esis ▁of ▁rip ost atin ▁A ▁features ▁two ▁concurrent ▁St ille ▁cou pl ings ▁followed ▁by ▁a ▁ring - clos ing ▁met ath esis . ▁ ▁The ▁synth esis ▁of ▁luc il act a ene ▁features ▁ ▁a ▁middle ▁sub unit , ▁having ▁a ▁bor ane ▁on ▁one ▁side ▁and ▁a ▁st ann ane ▁on ▁the ▁other , ▁allowing ▁for ▁St ille