▁Category : Sh ip ▁types ▁Category : 1 9 4 0 s ▁ships ▁Category : Container ▁ship ▁classes ▁Category : Sh ip ▁classes ▁+ <0x0A> </s> ▁Ret rom er ▁is ▁a ▁complex ▁of ▁prote ins ▁that ▁has ▁been ▁shown ▁to ▁be ▁important ▁in ▁rec y cling ▁transm emb rane ▁re cept ors ▁from ▁end os om es ▁to ▁the ▁trans - G ol gi ▁network ▁( T GN ). ▁ ▁Background ▁▁ ▁Ret rom er ▁is ▁a ▁heter op ent amer ic ▁complex ▁which ▁in ▁humans ▁is ▁composed ▁of ▁a ▁less ▁defined ▁memb rane - associ ated ▁sorting ▁ne x in ▁dim er ▁( SN X 1 , ▁SN X 2 , ▁SN X 5 , ▁SN X 6 ), ▁and ▁a ▁vac u olar ▁protein ▁sorting ▁( V ps ) ▁tr imer ▁containing ▁V ps 2 6 , ▁V ps 2 9 , ▁V ps 3 5 . ▁Although ▁the ▁SN X ▁dim er ▁is ▁required ▁for ▁the ▁rec ruit ment ▁of ▁ret rom er ▁to ▁the ▁end os om al ▁memb rane , ▁the ▁cargo ▁binding ▁function ▁of ▁this ▁complex ▁is ▁contributed ▁by ▁the ▁core ▁tr imer ▁through ▁the ▁binding ▁of ▁V ps 3 5 ▁sub unit ▁to ▁various ▁cargo ▁mole cules ▁ ▁including ▁M 6 PR ▁w nt less ▁and ▁sort il in . ▁Early ▁study ▁on ▁sorting ▁of ▁acid ▁hyd rol ases ▁such ▁as ▁car box ype pt id ase ▁Y ▁( CP Y ) ▁in ▁S . ▁c ere vis iae ▁mut ants ▁has ▁led ▁to ▁the ▁identification