ics ▁natural ▁mus k . ▁It ▁has ▁been ▁used ▁as ▁a ▁perf ume ▁fix ative ▁in ▁a ▁wide ▁variety ▁of ▁consumer ▁products , ▁and ▁is ▁still ▁used ▁in ▁some ▁cos met ics ▁and ▁fra gr ances . ▁ ▁Mus k ▁x yl ene ▁was ▁once ▁the ▁most ▁widely ▁used ▁of ▁the ▁" nit ro - mus ks ", ▁but ▁its ▁use ▁has ▁decl ined ▁sharp ly ▁since ▁the ▁mid - 1 9 8 0 s ▁due ▁to ▁safety ▁and ▁environmental ▁concerns . ▁Its ▁explos ive ▁and ▁car cin ogen ic ▁ha z ards ▁are ▁recognized ▁to ▁be ▁border line , ▁and ▁mus k ▁x yl ene ▁is ▁a ▁useful ▁example ▁of ▁the ▁lowest ▁level ▁of ▁such ▁ris ks ▁which ▁need ▁to ▁be ▁taken ▁into ▁account . ▁However , ▁it ▁is ▁a ▁very ▁persistent ▁and ▁very ▁bio acc um ulative ▁poll ut ant ▁in ▁the ▁aqu atic ▁environment ▁( v P v B ▁subst ance ), ▁and ▁is ▁the ▁first ▁subst ance ▁to ▁be ▁proposed ▁as ▁a ▁" subst ance ▁of ▁very ▁high ▁concern " ▁( SV HC ) ▁for ▁these ▁reasons ▁alone ▁under ▁the ▁European ▁Union ▁RE AC H ▁Reg ulation . ▁Since ▁no ▁company ▁has ▁applied ▁for ▁author isation , ▁it ▁is ▁b anned ▁in ▁the ▁EU . ▁ ▁Production ▁and ▁use ▁Mus k ▁x yl ene ▁is ▁produced ▁from ▁meta - x yl ene ▁( 1 , 3 - dim eth yl ben z ene ), ▁by ▁a ▁Fried el – C raft s ▁alk yl ation ▁with ▁t ert -