K ▁signal ing ▁path way ▁reg ulating ▁the ▁activity ▁of ▁the ▁AP - 1 ▁protein , ▁which , ▁in ▁turn , ▁indu ces ▁the ▁development ▁of ▁M ET . ▁Investig ation ▁of ▁the ▁possibility ▁of ▁using ▁the ▁P D 1 7 3 0 7 4 ▁in hib itor ▁as ▁a ▁drug , ▁which ▁was ▁conducted ▁on ▁specific ▁tum or ▁cell ▁lines , ▁revealed ▁a ▁distinct ▁supp ression ▁of ▁tum or ▁growth , ▁migration ▁ability , ▁and ▁invasion . ▁In ▁this ▁case , ▁a ▁decrease ▁in ▁the ▁expression ▁of ▁Sn ail ▁and ▁the ▁matrix ▁metal lo prote in ase ▁ 3 , ▁ 1 0 , ▁ 1 2 ▁and ▁ 1 3 ▁gen es ▁and ▁an ▁increase ▁in ▁the ▁expression ▁of ▁the ▁E - c ad her in ▁gene ▁were ▁observed . ▁ ▁Classification ▁of ▁invas ive ▁growth ▁types ▁on ▁the ▁example ▁of ▁breast ▁cancer ▁For ▁many ▁years , ▁our ▁research ▁team ▁has ▁studied ▁the ▁features ▁of ▁breast ▁cancer ▁pro gression ▁depending ▁on ▁intr atum oral ▁heter ogene ity . ▁Part icular ▁attention ▁has ▁been ▁paid ▁to ▁the ▁phen ot yp ic ▁divers ity ▁of ▁the ▁primary ▁tum or ▁in ▁invas ive ▁car cin oma ▁of ▁no ▁special ▁type , ▁which ▁accounts ▁for ▁the ▁bulk ▁( 8 0 %) ▁of ▁all ▁hist ological ▁types ▁of ▁breast ▁cancer . <0x09> ▁ <0x09> ▁Despite ▁the ▁considerable ▁struct ural ▁divers ity ▁of ▁the ▁primary ▁breast ▁tum or , ▁five ▁main ▁types ▁of ▁morph ological ▁structures ▁can ▁be ▁distinguished : ▁al ve olar , ▁trab ec ular