y , ▁whose ▁ser mon ▁reached ▁North ▁America , ▁where ▁there ▁was ▁early ▁religious ▁opposition , ▁particularly ▁by ▁John ▁Williams . ▁A ▁greater ▁source ▁of ▁opposition ▁there ▁was ▁Dr . ▁William ▁Doug lass , ▁a ▁medical ▁gradu ate ▁of ▁Edinburgh ▁University ▁and ▁a ▁Fellow ▁of ▁the ▁Royal ▁Society , ▁who ▁had ▁settled ▁in ▁Boston . ▁ ▁Small po x ▁v acc ination ▁ ▁After ▁Edward ▁Jen ner ▁introduced ▁the ▁small po x ▁v acc ine ▁in ▁ 1 7 9 8 , ▁vari olation ▁decl ined ▁and ▁was ▁b anned ▁in ▁some ▁countries . ▁As ▁with ▁vari olation , ▁there ▁was ▁some ▁religious ▁opposition ▁to ▁v acc ination , ▁although ▁this ▁was ▁bal anced ▁to ▁some ▁extent ▁by ▁support ▁from ▁cl erg ymen , ▁such ▁as ▁Re ver end ▁Robert ▁Fer ry man , ▁a ▁friend ▁of ▁Jen ner ' s , ▁and ▁Row land ▁Hill , ▁who ▁not ▁only ▁pre ached ▁in ▁its ▁favour ▁but ▁also ▁performed ▁v acc ination ▁themselves . ▁There ▁was ▁also ▁opposition ▁from ▁some ▁vari ol ators ▁who ▁saw ▁the ▁loss ▁of ▁a ▁luc r ative ▁mon opol y . ▁William ▁Row ley ▁published ▁illustr ations ▁of ▁de form ities ▁alleg edly ▁produced ▁by ▁v acc ination , ▁l am po oned ▁in ▁James ▁Gill ray ' s ▁famous ▁car ic ature ▁dep icted ▁on ▁this ▁page , ▁and ▁Benjamin ▁M ose ley ▁li ken ed ▁cow po x ▁to ▁sy ph ilis , ▁starting ▁a ▁controvers y ▁that ▁would ▁last ▁into ▁the ▁ 2 0 th ▁century