bra in ▁bar rier ▁and ▁its ▁ability ▁to ▁transport ▁multiple ▁kinds ▁of ▁mole cules ▁out ▁of ▁cells , ▁AB CC 1 ▁has ▁been ▁a ▁point ▁of ▁interest ▁in ▁many ▁Al z heimer ' s ▁disease ▁studies . ▁The ▁trans porter ▁protein ▁has ▁been ▁shown ▁to ▁decrease ▁ β - amy lo id ▁accum ulation ▁by ▁nearly ▁ 8 0 ▁percent ▁when ▁activ ated , ▁leading ▁research ers ▁to ▁further ▁investigation ▁on ▁its ▁use ▁in ▁future ▁treat ments ▁of ▁Al z heimer ' s ▁and ▁other ▁ne uro log ical ▁dis orders . ▁ ▁Ro le ▁in ▁cancer ▁ ▁AB CC 1 ▁plays ▁a ▁role ▁in ▁the ▁mult id rug ▁resistance ▁of ▁cancer ous ▁tum or ▁cells ▁due ▁to ▁its ▁ability ▁to ▁transport ▁many ▁chem other ape ut ic ▁dru gs ▁out ▁of ▁the ▁cells . ▁The ▁AB CC 1 ▁trans porter ▁protein ▁is ▁especially ▁pre val ent ▁in ▁ne uro blast oma ▁and ▁cancer ▁cells ▁found ▁in ▁the ▁lung , ▁breast ▁and ▁pro state . ▁In ▁non - small ▁cell ▁lung ▁car cin oma ▁and ▁small ▁cell ▁lung ▁car cin oma , ▁higher ▁expression ▁of ▁AB CC 1 ▁was ▁indic ative ▁of ▁a ▁reduced ▁response ▁to ▁chem other ape ut ic ▁dru gs ▁and ▁a ▁lower ▁rate ▁of ▁surv ival . ▁Similar ▁results ▁were ▁found ▁in ▁early - stage ▁breast ▁cancer ▁where ▁the ▁increased ▁expression ▁of ▁the ▁trans porter ▁gene ▁correl ated ▁with ▁shorter ▁times ▁until ▁a ▁re lapse ▁occurred ▁and ▁lower ▁rates ▁of ▁surv ival . ▁In ▁pro state ▁cancer , ▁expression