, ▁o lig od end ro cy tem y elin ▁g ly cop rote in ▁and ▁my elin - associ ated ▁g ly cop rote in . ▁This ▁re ceptor ▁medi ates ▁ax onal ▁growth ▁in hib ition ▁and ▁may ▁play ▁a ▁role ▁in ▁reg ulating ▁ax onal ▁reg ener ation ▁and ▁pl astic ity ▁in ▁the ▁adult ▁central ▁nerv ous ▁system . ▁ ▁Function ▁ ▁The ▁N ogo - 6 6 ▁Re ceptor ▁( N g R ) ▁is ▁a ▁high ▁aff inity ▁binding ▁re ceptor ▁for ▁a ▁region ▁of ▁N ogo , ▁a ▁my elin ▁associated ▁protein ▁that ▁in hib its ▁ax on ▁out g row th . ▁Ng R ▁was ▁identified ▁by ▁Str itt m atter ▁and ▁colle agues ▁using ▁an ▁expression ▁cl oning ▁strategy . ▁ ▁Ng R ▁is ▁imp licated ▁in ▁neur onal ▁pl astic ity ▁and ▁reg ener ation . ▁ ▁Its ▁relative ▁importance ▁in ▁medi ating ▁my elin ▁in hib ition ▁in ▁vit ro ▁and ▁in ▁v ivo ▁is ▁currently ▁under ▁inten se ▁investigation , ▁since ▁this ▁protein ▁might ▁be ▁a ▁good ▁drug ▁target ▁for ▁treatment ▁of ▁various ▁ne uro log ical ▁conditions ▁such ▁as ▁sp inal ▁cord ▁injury ▁and ▁stroke . ▁ ▁N ogo ▁path way : ▁r ho ▁kin ase ▁ ▁While ▁the ▁entire ▁path way ▁is ▁not ▁fully ▁understood , ▁the ▁relationship ▁between ▁Ng R ▁and ▁neur onal ▁out g row th ▁has ▁been ▁f les hed ▁out . ▁ ▁Ng R ▁is ▁a ▁memb rane ▁protein ▁that , ▁when ▁bound ▁to ▁neur