▁Anti - CD 8 1 ▁ant ib od ies ▁down reg ulate ▁H IV ▁production ▁ 3 ▁fol d , ▁however ▁the ▁CD 8 1 ▁protein ▁free ▁virus ▁is ▁more ▁inf ect ious . ▁Eng agement ▁of ▁CD 8 1 ▁low ers ▁the ▁signal ing ▁threshold ▁required ▁to ▁trigger ▁T - Cell \ CD 3 ▁medi ated ▁prov iral ▁DNA ▁in ▁CD 4 + ▁T ▁cells . ▁ ▁CD 8 1 ▁appears ▁to ▁play ▁a ▁role ▁in ▁the ▁path ogen esis ▁of ▁influen za . ▁ ▁Inter actions ▁▁ ▁CD 8 1 ▁has ▁been ▁shown ▁to ▁interact ▁with ▁T SP AN 4 , ▁CD 1 9 , ▁CD 9 , ▁P T G FR N , ▁CD 1 1 7 ▁and ▁CD 2 9 . ▁ ▁Lig ands ▁ ▁Ben zy l ▁sal ic yl ate ▁and ▁ter fen ad ine ▁have ▁been ▁shown ▁to ▁bind ▁to ▁CD 8 1 . ▁ ▁See ▁also ▁ ▁Cl uster ▁of ▁different iation ▁ ▁References ▁ ▁Further ▁reading ▁ ▁External ▁links ▁▁▁▁▁ ▁Category : Cl ust ers ▁of ▁different iation <0x0A> </s> ▁Carlo ▁Gar b ieri ▁was ▁an ▁Italian ▁painter ▁of ▁the ▁early ▁Bar o que ▁period . ▁He ▁is ▁the ▁son ▁and ▁scholar ▁of ▁Lorenzo ▁Gar b ieri , ▁painted ▁historical ▁subjects ▁in ▁the ▁style ▁of ▁his ▁father . ▁In ▁the ▁church ▁of ▁San ▁Giovanni ▁in ▁Monte , ▁at ▁Bolog na , ▁is ▁a ▁picture ▁by ▁him ▁of ▁the ▁Death ▁of ▁St ▁Mary ▁of ▁Egypt ; ▁and ▁in ▁the ▁church ▁of ▁San ▁Paolo ▁is ▁a