. ▁It ▁is ▁mainly ▁based ▁on ▁age , ▁gender , ▁di ab etes , ▁total ▁ch ol ester ol , ▁HD L ▁ch ol ester ol , ▁to b acco ▁sm oking ▁and ▁syst ol ic ▁blood ▁pressure . ▁When ▁it ▁comes ▁to ▁predict ing ▁risk ▁in ▁younger ▁adult s ▁( 1 8 – 3 9 ▁years ▁old ), ▁F ram ingham ▁R isk ▁Sc ore ▁remains ▁below ▁ 1 0 - 1 2 % ▁for ▁all ▁dec iles ▁of ▁bas eline - pred icted ▁risk . ▁ ▁Poly gen ic ▁score ▁is ▁another ▁way ▁of ▁risk ▁assess ment . ▁In ▁one ▁study ▁the ▁relative ▁risk ▁of ▁incident ▁coron ary ▁events ▁was ▁ 9 1 % ▁higher ▁among ▁participants ▁at ▁high ▁gen etic ▁risk ▁than ▁among ▁those ▁at ▁low ▁gen etic ▁risk . ▁ ▁Pre vention ▁Up ▁to ▁ 9 0 % ▁of ▁card i ov asc ular ▁disease ▁may ▁be ▁prevent able ▁if ▁established ▁risk ▁factors ▁are ▁avoided . ▁Pre vention ▁involves ▁ade qu ate ▁physical ▁exercise , ▁decre asing ▁ob es ity , ▁tre ating ▁high ▁blood ▁pressure , ▁e ating ▁a ▁health y ▁di et , ▁decre asing ▁ch ol ester ol ▁levels , ▁and ▁stopping ▁sm oking . ▁Medic ations ▁and ▁exercise ▁are ▁roughly ▁equally ▁effective . ▁High ▁levels ▁of ▁physical ▁activity ▁reduce ▁the ▁risk ▁of ▁coron ary ▁ar tery ▁disease ▁by ▁about ▁ 2 5 %. ▁ ▁Most ▁gu idel ines ▁recommend ▁combining ▁these ▁prevent ive ▁strateg ies . ▁A ▁ 2 0 1 5 ▁C och rane