- SC AR S ▁lack ▁most ▁of ▁the ▁characteristics ▁of ▁trans ient , ▁revers ible ▁DNA ▁damage ▁fo ci , ▁such ▁as ▁single - str and ed ▁DNA , ▁active ▁DNA ▁synth esis , ▁and ▁DNA ▁repair ▁prote ins ▁R PA ▁and ▁R AD 5 1 . ▁Tel om ere ▁d ys function - indu ced ▁fo ci ▁( T IF ) ▁are ▁generally ▁associated ▁with ▁DNA - SC AR S . ▁ ▁T ogether ▁with ▁sen esc ence - associ ated ▁heter och rom atin ▁fo ci ▁( SA H F ), ▁DNA - SC AR S ▁are ▁one ▁of ▁the ▁most ▁pre val ent ▁nuclear ▁markers ▁of ▁cell ular ▁sen esc ence . ▁ ▁History ▁ ▁DNA - SC AR S ▁were ▁discovered ▁by ▁Jud ith ▁Camp isi ▁and ▁colle agues , ▁who ▁first ▁described ▁them ▁in ▁ 2 0 1 1 , ▁although ▁most ▁of ▁their ▁characteristics ▁were ▁previously ▁known . ▁ ▁References ▁▁ ▁Category : Cell ular ▁sen esc ence ▁Category : Cell ▁nucle us ▁Category : D NA <0x0A> </s> ▁James ▁Edward ▁Ca ul fe ild , ▁ 8 th ▁Vis count ▁Char lem ont , ▁PC ▁( NI ), ▁D L ▁( 1 2 ▁May ▁ 1 8 8 0 ▁– ▁ 2 0 ▁August ▁ 1 9 4 9 ) ▁was ▁an ▁Irish ▁Pe er , ▁elected ▁to ▁the ▁British ▁House ▁of ▁L ords ▁as ▁a ▁Represent ative ▁Pe er ▁and ▁to ▁the ▁Parliament ▁of ▁Northern ▁Ireland ▁as ▁a ▁Senator . ▁He ▁sat ▁in ▁Storm ont