▁ 4 8 % ▁of ▁the ▁sequence ▁for ▁A po B 1 0 0 . ▁ ▁A po B ▁ 4 8 ▁is ▁a ▁unique ▁protein ▁to ▁ch yl omic rons ▁from ▁the ▁small ▁int est ine . ▁After ▁most ▁of ▁the ▁lip ids ▁in ▁the ▁ch yl omic ron ▁have ▁been ▁absor bed , ▁A po B 4 8 ▁returns ▁to ▁the ▁li ver ▁as ▁part ▁of ▁the ▁ch yl omic ron ▁rem nant , ▁where ▁it ▁is ▁end oc yt osed ▁and ▁de grad ed . ▁ ▁C lin ical ▁significance ▁ ▁Ben ef its ▁ ▁Ro le ▁in ▁inn ate ▁imm une ▁system ▁ ▁Very ▁low - dens ity ▁li pop rote ins ▁and ▁low - dens ity ▁li pop rote ins ▁inter f ere ▁with ▁the ▁qu orum ▁sens ing ▁system ▁that ▁up reg ul ates ▁gen es ▁required ▁for ▁invas ive ▁St ap hy loc oc cus ▁a ure us ▁in fection . ▁The ▁mechanism ▁of ▁ant agon ism ▁ent ails ▁binding ▁A po B , ▁to ▁a ▁S . ▁a ure us ▁auto ind uc er ▁ph er om one , ▁prevent ing ▁signal ing ▁through ▁its ▁re ceptor . ▁M ice ▁def ic ient ▁in ▁A po B ▁are ▁more ▁sus cept ible ▁to ▁invas ive ▁ ▁b acter ial ▁in fection . ▁ ▁Ad verse ▁effects ▁ ▁Ro le ▁in ▁ins ul in ▁resistance ▁ ▁Over production ▁of ▁ap ol ip op rote in ▁B ▁can ▁result ▁in ▁li pid - indu ced ▁end op