▁ 1 8 0 0 s . ▁ ▁Opt imal ▁designs ▁for ▁regression ▁models ▁ ▁Charles ▁S . ▁Pe ir ce ▁also ▁contributed ▁the ▁first ▁English - language ▁publication ▁on ▁an ▁optimal ▁design ▁for ▁regression ▁models ▁in ▁ 1 8 7 6 . ▁A ▁pione ering ▁optimal ▁design ▁for ▁polynomial ▁regression ▁was ▁suggested ▁by ▁Ger g onne ▁in ▁ 1 8 1 5 . ▁In ▁ 1 9 1 8 , ▁K irst ine ▁Smith ▁published ▁optimal ▁designs ▁for ▁polynomials ▁of ▁degree ▁six ▁( and ▁less ). ▁ ▁Se qu ences ▁of ▁experiments ▁ ▁The ▁use ▁of ▁a ▁sequence ▁of ▁experiments , ▁where ▁the ▁design ▁of ▁each ▁may ▁depend ▁on ▁the ▁results ▁of ▁previous ▁experiments , ▁including ▁the ▁possible ▁decision ▁to ▁stop ▁experiment ing , ▁is ▁within ▁the ▁scope ▁of ▁Se qu ential ▁analysis , ▁a ▁field ▁that ▁was ▁pione ered ▁by ▁Abraham ▁Wald ▁in ▁the ▁context ▁of ▁sequ ential ▁tests ▁of ▁statistical ▁hypoth eses . ▁H erman ▁Ch ern off ▁wrote ▁an ▁over view ▁of ▁optimal ▁sequ ential ▁designs , ▁while ▁adapt ive ▁designs ▁have ▁been ▁survey ed ▁by ▁S . ▁Z acks . ▁One ▁specific ▁type ▁of ▁sequ ential ▁design ▁is ▁the ▁" two - ar med ▁band it ", ▁generalized ▁to ▁the ▁multi - ar med ▁band it , ▁on ▁which ▁early ▁work ▁was ▁done ▁by ▁Herbert ▁Rob b ins ▁in ▁ 1 9 5 2 . ▁ ▁Fish er ' s ▁principles ▁ ▁A ▁method ology ▁for ▁design ing ▁experiments ▁was ▁proposed ▁by ▁Ron ald ▁Fish er , ▁in