▁race hor se ▁death s ▁Category : Th or ough bre d ▁family ▁ 4 - l ▁Category : By er ley ▁Turk ▁s ire ▁line ▁Category : 1 0 0 0 ▁Gu ine as ▁w inners <0x0A> </s> ▁L ix iv apt an ▁( V PA - 9 8 5 ) ▁is ▁a ▁phase ▁III ▁ph arma ce ut ical ▁being ▁developed ▁by ▁Card i ok ine , ▁Inc ., ▁a ▁special ty ▁ph arma ce ut ical ▁company ▁based ▁in ▁Philadelphia , ▁PA , ▁focused ▁on ▁the ▁development ▁of ▁ph arma ce ut ical s ▁for ▁the ▁treatment ▁and ▁prevent ion ▁of ▁card i ov asc ular ▁dise ases . ▁L ix iv apt an ▁is , ▁as ▁of ▁May ▁ 2 0 1 0 , ▁in ▁Ph ase ▁III ▁clin ical ▁tri als ▁involving ▁patients ▁with ▁hy pon at rem ia , ▁including ▁those ▁with ▁con com it ant ▁heart ▁failure . ▁Hy pon at rem ia ▁is ▁an ▁electro ly te ▁disturb ance ▁in ▁which ▁the ▁sod ium ▁concentration ▁in ▁the ▁ser um ▁is ▁lower ▁than ▁normal . ▁L ix iv apt an ▁may ▁help ▁some ▁patients ▁eliminate ▁excess ▁flu ids ▁while ▁retain ing ▁electro ly tes . ▁ ▁Chem istry ▁L ix iv apt an ▁is ▁synth es ized ▁as ▁follows : ▁ ▁Mechan ism ▁of ▁action ▁L ix iv apt an ▁is ▁a ▁pot ent , ▁non - pe pt ide , ▁select ive ▁vas op ress in ▁ 2 ▁re ceptor ▁ant agon ist . ▁The