▁which ▁possess ▁a ▁unique ▁feature ▁of ▁t issue ▁specific ity ▁in ▁their ▁action ▁on ▁hom olog ous ▁t issue ▁cells ▁without ▁species ▁specific ity . ▁The ▁second ▁one ▁is ▁increase ▁in ▁sens itivity ▁of ▁dam aged ▁cells ▁to ▁these ▁regul ators , ▁as ▁it ▁was ▁demonstrated ▁on ▁the ▁example ▁of ▁com ut on . ▁These ▁effect ors ▁cause ▁t issues pec ific ▁self - dam age ▁of ▁hom olog ous ▁cells ▁via ▁disturb ance ▁of ▁their ▁ion ▁home ost asis ▁and ▁energy - production ▁processes . ▁As ▁a ▁result , ▁un specific ▁reaction ▁to ▁damage ▁( CUR D ) ▁is ▁activ ated ▁in ▁the ▁cells . ▁This ▁universal ▁phys i ological ▁reaction ▁plays ▁a ▁role ▁of ▁T AS ▁executive ▁mechanism . ▁Thus , ▁the ▁adapt ive ▁function ▁of ▁t issue ▁stress ▁is ▁brought ▁into ▁action ▁using ▁such ▁C UR D ▁properties ▁as ▁increase ▁of ▁cell ▁un specific ▁resistance , ▁as ▁well ▁as ▁influence ▁on ▁the ▁rate ▁of ▁cell ▁met abol ic ▁processes . ▁It ▁is ▁obvious ▁that ▁in ▁the ▁case ▁of ▁T AS ▁these ▁changes ▁have ▁to ▁be ▁t issues pec ific , ▁since ▁they ▁are ▁initi ated ▁by ▁way ▁of ▁cell ▁self - dam age ▁under ▁t issues pec ific ▁influence ▁of ▁T AS ▁effect ors . ▁ ▁As ▁is ▁well ▁known ▁the ▁C UR D ▁consists ▁of ▁two ▁phases . ▁In ▁the ▁process ▁of ▁a ▁slight ▁damage ▁of ▁the ▁cell ▁the ▁phase ▁of ▁met abol ism ▁stim ulation ▁is ▁forming ▁in ▁it . ▁When ▁the ▁cell ▁is ▁slightly ▁dam aged ,