▁impro per ▁in activ ation ▁can ▁result ▁in ▁int act ▁and ▁inf ect ious ▁particles . ▁Because ▁the ▁killed ▁path og ens ▁in ▁a ▁properly ▁produced ▁v acc ine ▁do ▁not ▁reproduce , ▁boost er ▁sh ots ▁are ▁required ▁period ically ▁to ▁rein force ▁the ▁imm une ▁response . ▁ ▁References ▁ ▁Category : V acc ines ▁Category : In activ ated ▁v acc ines <0x0A> </s> ▁Hern ández ▁is ▁a ▁w ides p read ▁Spanish ▁surname ▁that ▁became ▁common ▁around ▁the ▁ 1 5 th ▁century . ▁Origin ally ▁a ▁patron ym ic , ▁it ▁means ▁son ▁of ▁Hern án , ▁Hern ando ▁or ▁Fernando — the ▁Spanish ▁version ▁of ▁German ic ▁Ferdinand . ▁Fernández ▁is ▁a ▁very ▁common ▁variant ▁of ▁the ▁name . ▁Hern and es ▁and ▁Fern and es ▁are ▁their ▁Portuguese ▁equival ents . ▁ ▁The ▁fact ▁that ▁the ▁Hern ández ▁family ▁of ▁Spain ▁be ars ▁a ▁version ▁of ▁the ▁French ▁royal ▁arms ▁leads ▁many ▁to ▁spec ulate ▁that ▁they ▁descend ▁from ▁the ▁French ▁royal ▁house ▁of ▁Val ois . ▁ ▁Ge ographical ▁distribution ▁As ▁of ▁ 2 0 1 4 , ▁ 5 2 . 9 % ▁of ▁all ▁known ▁bear ers ▁of ▁the ▁surname ▁Hern ández ▁were ▁residents ▁of ▁Mexico ▁( fre quency ▁ 1 : 2 5 ), ▁ 7 . 7 % ▁of ▁the ▁United ▁States ▁( 1 : 5 1 0 ), ▁ 6 . 3 % ▁of ▁Colombia ▁( 1 : 8 3 ), ▁ 5 . 8 % ▁of ▁Venezuela ▁( 1