ass es ▁out right ▁ref us al ▁to ▁v acc inate , ▁delay ing ▁v acc ines , ▁accepting ▁v acc ines ▁but ▁remaining ▁uncertain ▁about ▁their ▁use , ▁or ▁using ▁certain ▁v acc ines ▁but ▁not ▁others . ▁Arg uments ▁against ▁v acc ination ▁are ▁contrad icted ▁by ▁over wh el ming ▁scientific ▁cons ensus ▁about ▁the ▁safety ▁and ▁effic acy ▁of ▁v acc ines . ▁ ▁H es it ancy ▁primarily ▁results ▁from ▁public ▁deb ates ▁around ▁the ▁medical , ▁eth ical ▁and ▁legal ▁issues ▁related ▁to ▁v acc ines . ▁V acc ine ▁hes it ancy ▁st ems ▁from ▁multiple ▁key ▁factors ▁including ▁a ▁person ' s ▁lack ▁of ▁confidence ▁( m istr ust ▁of ▁the ▁v acc ine ▁and / or ▁health care ▁provider ), ▁comp lac ency ▁( the ▁person ▁does ▁not ▁see ▁a ▁need ▁for ▁the ▁v acc ine ▁or ▁does ▁not ▁see ▁the ▁value ▁of ▁the ▁v acc ine ), ▁and ▁convenience ▁( access ▁to ▁v acc ines ). ▁It ▁has ▁existed ▁since ▁the ▁in vention ▁of ▁v acc ination , ▁and ▁pre - dates ▁the ▁co ining ▁of ▁the ▁terms ▁" v acc ine " ▁and ▁" v acc ination " ▁by ▁nearly ▁ 8 0 ▁years . ▁The ▁specific ▁hypoth eses ▁raised ▁by ▁anti - v acc ination ▁advoc ates ▁have ▁been ▁found ▁to ▁change ▁over ▁time . ▁V acc ine ▁hes it ancy ▁often ▁results ▁in ▁disease ▁out break s ▁and ▁death s ▁from ▁v acc ine - prevent able ▁dise ases .