5 ▁re ceptor ▁( CD 1 2 5 ). ▁ ▁Two ▁Ph ase ▁ 3 ▁clin ical ▁tri als ▁of ▁ben ral iz um ab , ▁SI RO C CO ▁and ▁C AL IMA , ▁reported ▁meeting ▁their ▁primary ▁end points ▁in ▁ 2 0 1 6 . ▁It ▁was ▁approved ▁by ▁the ▁US ▁F DA ▁in ▁November ▁ 2 0 1 7 ▁for ▁the ▁treatment ▁of ▁severe ▁e os in oph il ic ▁ast h ma . ▁It ▁was ▁also ▁granted ▁or phan ▁drug ▁design ation ▁by ▁the ▁F DA ▁for ▁treatment ▁of ▁e os in oph il ic ▁o es oph agit is ▁in ▁August ▁ 2 0 1 9 . ▁ ▁References ▁▁ ▁Category : Ant ias thm atic ▁dru gs ▁Category : Mon oc l onal ▁ant ib od ies ▁Category : A stra Z en eca ▁br ands <0x0A> </s> ▁The ▁ 2 0 0 4 – 0 5 ▁Tun is ian ▁Ligue ▁Prof ession nelle ▁ 1 ▁season ▁was ▁the ▁ 7 9 th ▁season ▁of ▁top - t ier ▁football ▁in ▁Tun is ia . ▁ ▁Results ▁ ▁League ▁table ▁ ▁Result ▁table ▁ ▁Le aders ▁ ▁References ▁ 2 0 0 4 – 0 5 ▁Ligue ▁ 1 ▁on ▁R SS SF . com ▁ ▁Category : T un is ian ▁Ligue ▁Prof ession nelle ▁ 1 ▁seasons ▁ 1 ▁Tun <0x0A> </s> ▁The ▁County ▁Bor ough ▁of ▁D ud ley ▁was ▁a ▁local ▁government ▁district ▁in ▁the ▁English ▁Mid lands ▁from ▁ 1 8