▁( 2 0 0 6 ) ▁found ▁that ▁some ▁ne uro trans mit ter ▁systems ▁are ▁affected ▁by ▁exercise ▁in ▁a ▁positive ▁way . ▁A ▁few ▁studies ▁reported ▁seeing ▁an ▁improvement ▁in ▁brain ▁health ▁and ▁cogn itive ▁function ▁due ▁to ▁exercise . ▁One ▁particular ▁study ▁by ▁K ram er ▁and ▁colle agues ▁( 1 9 9 9 ) ▁found ▁that ▁aer ob ic ▁training ▁improved ▁executive ▁control ▁processes ▁supported ▁by ▁front al ▁and ▁pre front al ▁regions ▁of ▁the ▁brain . ▁These ▁regions ▁are ▁responsible ▁for ▁the ▁cogn itive ▁def ic its ▁in ▁P D ▁patients , ▁however ▁there ▁was ▁spec ulation ▁that ▁the ▁difference ▁in ▁the ▁ne uro chem ical ▁environment ▁in ▁the ▁front al ▁lo bes ▁of ▁P D ▁patients ▁may ▁in hib it ▁the ▁benefit ▁of ▁aer ob ic ▁exercise . ▁N oc era ▁and ▁colle agues ▁( 2 0 1 0 ) ▁performed ▁a ▁case ▁study ▁based ▁on ▁this ▁literature ▁where ▁they ▁gave ▁participants ▁with ▁early - to ▁mid - st aged ▁P D , ▁and ▁the ▁control ▁group ▁cogn itive / language ▁assess ments ▁with ▁exercise ▁reg im ens . ▁Ind ividual s ▁performed ▁ 2 0 ▁minutes ▁of ▁aer ob ic ▁exercise ▁three ▁times ▁a ▁week ▁for ▁ 8 ▁weeks ▁on ▁a ▁station ary ▁exercise ▁cycle . ▁It ▁was ▁found ▁that ▁aer ob ic ▁exercise ▁improved ▁several ▁measures ▁of ▁cogn itive ▁function , ▁providing ▁evidence ▁that ▁such ▁exercise ▁reg im ens ▁may ▁be ▁benef icial ▁to ▁patients ▁with ▁P D . ▁ ▁See ▁also ▁ ▁Bra in