. ▁The ▁first ▁novel ▁comp ound ▁detected ▁was ▁N , ▁N '- bis ( 4 - gu an id in ob ut yl ) ox al am ide , ▁the ▁major ▁component , ▁but ▁of ▁unknown ▁effects . ▁In ▁addition , ▁there ▁are ▁about ▁ 5 0 ▁different ▁pe pt ide ▁to x ins . ▁The ▁most ▁bi olog ically ▁active ▁pe pt ides ▁are ▁collect ively ▁called ▁p lect ox ins , ▁and ▁they ▁show ▁high ▁insect ic idal ▁activities ▁on ▁le pid opter an ▁insect s . ▁ ▁C lin ical ▁case ▁ ▁The ▁first ▁clin ical ▁case ▁of ▁P . ▁tr ist is ▁b ite ▁was ▁reported ▁in ▁ 1 9 9 1 . ▁A ▁ 1 5 - year - old ▁boy ▁was ▁bit ten ▁on ▁the ▁cal f ▁of ▁the ▁leg ▁in ▁K ern ▁County , ▁California . ▁He ▁initially ▁experienced ▁severe ▁pain , ▁o ed ema , ▁and ▁p all or ▁at ▁the ▁site ▁of ▁the ▁w ound . ▁After ▁ 1 5 ▁to ▁ 3 0 ▁minutes , ▁his ▁leg ▁became ▁num b ▁which ▁last ed ▁for ▁about ▁an ▁hour . ▁Then ▁the ▁num b ness ▁gradually ▁subs ided . ▁After ▁ 2 ▁hours , ▁all ▁sympt oms ▁were ▁gone ▁without ▁any ▁medical ▁inter vention . ▁ ▁References ▁ ▁External ▁links ▁Tax onomy ▁at ▁Z ip code Z oo ▁Animal ▁D iversity ▁Web ▁Ven om ▁information ▁at ▁A rach no Server ▁Compar ative ▁To xic ogen om ics ▁Database ▁Tax onomy ▁at ▁The ▁Tax onom icon