▁alter ed ▁invas iveness , ▁which ▁was ▁due ▁to ▁changes ▁in ▁Mit ogen - activ ated ▁protein ▁kin ase ▁signal ing ▁and ▁matrix ▁metal lo prote in ase ▁expression . ▁ ▁References ▁ ▁Further ▁reading <0x0A> </s> ▁Clay ton ▁Town send ▁( born ▁ 9 ▁February ▁ 1 9 6 1 ) ▁is ▁an ▁American ▁film ▁producer , ▁television ▁producer ▁and ▁production ▁manager . ▁Between ▁ 1 9 8 8 ▁and ▁ 1 9 9 9 ▁he ▁collabor ated ▁intens ively ▁with ▁director ▁Oliver ▁Stone ▁as ▁( co -) produ cer ▁and ▁associate ▁producer . ▁Notable ▁mov ies ▁from ▁that ▁period ▁are ▁Born ▁on ▁the ▁Four th ▁of ▁July ▁( 1 9 8 9 ), ▁Natural ▁Born ▁Kill ers ▁( 1 9 9 4 ) ▁and ▁Any ▁Given ▁Sunday ▁( 1 9 9 9 ). ▁Other ▁notable ▁producer ▁achiev ements ▁are ▁Ab el ▁Ferr ara ' s ▁The ▁Black out ▁( 1 9 9 7 ) ▁and ▁Where ' s ▁Mar low e ? ▁( 1 9 9 8 ), ▁directed ▁by ▁Daniel ▁Py ne . ▁He ▁also ▁served ▁as ▁an ▁executive ▁producer ▁on ▁the ▁M GM ▁comedy ▁Heart break ers ▁( 2 0 0 1 ), ▁directed ▁by ▁David ▁M irk in , ▁and ▁on ▁Bad ▁Company ▁( 2 0 0 2 ), ▁from ▁director ▁Jo el ▁Sch um acher . ▁In ▁addition ▁to ▁feature ▁films , ▁Clay ton ▁has ▁produced ▁several ▁television ▁pil ots ▁for ▁Param ount ▁Television , ▁including ▁the ▁ 2 0 0 3 ▁tele film ▁Hom eland ▁Security