▁of ▁h orm onal ▁synd rom es . ▁For ▁C ushing ' s ▁synd rome ▁( gl uc oc ort ico id ▁excess ), ▁these ▁include ▁weight ▁gain , ▁mus cle ▁was ting , ▁pur ple ▁lines ▁on ▁the ▁ab d omen , ▁a ▁fat ty ▁" buff alo ▁hum p " ▁on ▁the ▁neck , ▁a ▁" mo on - like " ▁face , ▁and ▁thin ning , ▁frag ile ▁skin . ▁Vir il ism ▁( andro gen ▁excess ) ▁is ▁most ▁obvious ▁in ▁women , ▁and ▁may ▁produce ▁excess ▁fa cial ▁and ▁body ▁hair , ▁ac ne , ▁en larg ement ▁of ▁the ▁cl itor is , ▁deep ening ▁of ▁the ▁voice , ▁co ars ening ▁of ▁fa cial ▁features , ▁c ess ation ▁of ▁men stru ation . ▁Con n ▁synd rome ▁( min eral c ort ico id ▁excess ) ▁is ▁marked ▁by ▁high ▁blood ▁pressure , ▁which ▁can ▁result ▁in ▁head ache ▁and ▁hyp ok alem ia ▁( low ▁ser um ▁pot ass ium , ▁which ▁can ▁in ▁turn ▁produce ▁mus cle ▁weak ness , ▁confusion , ▁and ▁pal pit ations ), ▁low ▁pl asma ▁ren in ▁activity , ▁and ▁high ▁ser um ▁al d oster one . ▁Fem in ization ▁( estro gen ▁excess ) ▁is ▁most ▁readily ▁noted ▁in ▁men , ▁and ▁includes ▁breast ▁en larg ement , ▁decre ased ▁lib ido , ▁and ▁imp ot ence . ▁ ▁Path oph ys i ology ▁The ▁main ▁et i olog ic ▁factor ▁of ▁A CC ▁is ▁unknown