▁m Eq ▁per ▁liter . ▁High ▁blood ▁pot ass ium ▁does ▁not ▁generally ▁result ▁in ▁ad verse ▁effects ▁below ▁a ▁concentration ▁of ▁ 6 . 5 ▁to ▁ 7 ▁m Eq ▁per ▁liter . ▁Therefore , ▁the ▁increase ▁in ▁ser um ▁pot ass ium ▁level ▁is ▁usually ▁not ▁cat ast roph ic ▁in ▁otherwise ▁health y ▁patients . ▁ ▁Sever ely ▁high ▁blood ▁levels ▁of ▁pot ass ium ▁will ▁cause ▁changes ▁in ▁card iac ▁electro phys i ology , ▁which , ▁if ▁severe , ▁can ▁result ▁in ▁as yst ole . ▁ ▁M align ant ▁hyper ther m ia ▁▁ ▁M align ant ▁hyper ther m ia ▁( M H ) ▁from ▁su x am eth on ium ▁administration ▁can ▁result ▁in ▁a ▁dr astic ▁and ▁un control led ▁increase ▁in ▁ske let al ▁mus cle ▁ox id ative ▁met abol ism . ▁This ▁over wh el ms ▁the ▁body ' s ▁capacity ▁to ▁supply ▁o xygen , ▁remove ▁carbon ▁dio x ide , ▁and ▁reg ulate ▁body ▁temperature , ▁eventually ▁leading ▁to ▁circul atory ▁collapse ▁and ▁death ▁if ▁not ▁treated ▁quickly . ▁ ▁Sus cept ibility ▁to ▁m align ant ▁hyper ther m ia ▁is ▁often ▁inherited ▁as ▁an ▁aut os om al ▁dominant ▁dis order , ▁for ▁which ▁there ▁are ▁at ▁least ▁six ▁gen etic ▁lo ci ▁of ▁interest , ▁the ▁most ▁prominent ▁being ▁the ▁r yan od ine ▁re ceptor ▁gene ▁( RY R 1 ). ▁M H ▁sus cept ibility ▁is ▁phen ot ype ▁and ▁gen et ically ▁related