▁R NA ▁medi ated ▁trans position ; ▁they ▁have ▁been ▁called ▁retro trans pos ons , ▁and ▁they ▁const itute ▁ 2 5 – 4 0 % ▁of ▁most ▁m amm al ian ▁genom es . ▁Some ▁types ▁of ▁inter sp ers ed ▁repet itive ▁DNA ▁elements ▁allow ▁new ▁gen es ▁to ▁evol ve ▁by ▁un cou pling ▁similar ▁DNA ▁sequences ▁from ▁gene ▁conversion ▁during ▁me ios is . ▁ ▁In tra chrom os om al ▁and ▁inter chrom os om al ▁gene ▁conversion ▁Gene ▁conversion ▁acts ▁on ▁DNA ▁sequence ▁hom ology ▁as ▁its ▁substr ate . ▁There ▁is ▁no ▁requirement ▁that ▁the ▁sequence ▁hom ologies ▁lie ▁at ▁the ▁alle lic ▁positions ▁on ▁their ▁respective ▁chrom os om es ▁or ▁even ▁that ▁the ▁hom ologies ▁lie ▁on ▁different ▁chrom os om es . ▁Gene ▁conversion ▁events ▁can ▁occur ▁between ▁different ▁members ▁of ▁a ▁gene ▁family ▁situated ▁on ▁the ▁same ▁chrom os ome . ▁When ▁this ▁happens , ▁it ▁is ▁called ▁int rach rom os om al ▁gene ▁conversion ▁as ▁distinguished ▁from ▁inter chrom os om al ▁gene ▁conversion . ▁The ▁effect ▁of ▁hom ogen izing ▁DNA ▁sequences ▁is ▁the ▁same . ▁ ▁Ro le ▁of ▁inter sp ers ed ▁repet itive ▁DNA ▁Rep et itive ▁sequences ▁play ▁the ▁role ▁of ▁un cou pling ▁the ▁gene ▁conversion ▁network , ▁thereby ▁allowing ▁new ▁gen es ▁to ▁evol ve . ▁The ▁shorter ▁Al u ▁or ▁S INE ▁repet itive ▁DNA ▁are ▁special ized ▁for ▁un cou pling ▁int rach rom os om al ▁gene ▁conversion ▁while