ers in ia ▁p est is ▁( respons ible ▁for ▁pl ague ), ▁its ▁relatives , ▁and ▁Francis ella ▁t ular ensis ▁( the ▁organ ism ▁responsible ▁for ▁t ul are m ia ▁often ▁seen ▁in ▁hun ters ▁and ▁tra ppers ). ▁ ▁Some ▁Enter ob acter ia ceae , ▁Pseud omon as ▁s pp ., ▁Enter oc oc cus ▁s pp ., ▁St ap hy loc oc cus ▁a ure us ▁and ▁other ▁St ap hy loc oc cus ▁s pp . ▁have ▁varying ▁degrees ▁of ▁resistance ▁to ▁gent am ic in . ▁ ▁Ad verse ▁effects ▁Ad verse ▁effects ▁of ▁gent am ic in ▁can ▁range ▁from ▁less ▁severe ▁re actions , ▁such ▁as ▁n ause a ▁and ▁vom iting , ▁to ▁more ▁severe ▁re actions ▁including : ▁ ▁Low ▁blood ▁cell ▁counts ▁ ▁All erg ic ▁re actions ▁▁ ▁Ne ur om us cular ▁problems ▁ ▁N erve ▁damage ▁( ne urop ath y ) ▁ ▁Kid ney ▁damage ▁( ne ph ro to x icity ) ▁ ▁Ear ▁dis orders ▁( ot ot ox icity ) ▁Ne ph ro to x icity ▁and ▁o tot ox icity ▁are ▁thought ▁to ▁be ▁do se ▁related ▁with ▁higher ▁dos es ▁causing ▁greater ▁chance ▁of ▁to x icity . ▁These ▁two ▁to xic ities ▁may ▁have ▁delayed ▁presentation , ▁sometimes ▁not ▁appearing ▁until ▁after ▁comple ting ▁treatment . ▁ ▁Kid ney ▁damage ▁ ▁Kid ney ▁damage ▁is ▁a ▁problem ▁in ▁ 1 0 - 2 5 % ▁of ▁people ▁who ▁receive ▁am