Resident Evil 6 pre-orders hit 380,000 in Japan, according to Media Create figures, besting the previous pre-order record holder in the series, Resident Evil: Operation Raccoon City.
Operation Raccoon City pre-orders hit 118,000 and the game went on to sell 268,810 during its first week on PS3 and Xbox 360 combined.
Media Create also noted that Resident Evil 5 has sold 1.2 million copies on all formats in Japan since it launched in 2009.
Resident Evil 6 sold 676,585 units combined in its first week at retail in the region.