The main purpose of this presentation is to illustrate the applicability of SAMS to the Colorado River system. For this purpose we have utilized monthly data at 29 sites in the basin. Prior to using SAM& the data at some sites have been extended in order to make them cover the same period at all sites. Likewise, the data have been naturalized in order to remover the effect of regulation or diversions. SAMS has been used to determine basic statistics (mean, standard deviation, skewness, auto-correlations and cross-correlations) as well as storage and drought related statistics in both the original and transformed (into normally distributed flows) domains. Then the 29 site system was partitioned into a system comprised of key stations, substations and subsequent stations. Single site and multisite models and aggregation and disaggregation techniques have been utilized in order to determine synthetic monthly streamflows at all sites. The referred stochastic analysis of the Colorado River system is a joint effort between the USBR, CSU and the University of Colorados Center for Advanced Decision Support for Water and Environmental Systems (CADSWES) which will lead to an interface between SAMS and the RiverWare modeling framework which was developed for USBR and other cooperators by CADSWES.