The Surgical Pathology Module is part of the Integrated Course in Hematology, Infectious Diseases and Oncology.
The Module aims to provide basic notions on nomenclature, etiology, physio-pathology and anatomical bases of hemo-lympho-proliferative disease in particular disease of the lymphatic organs. The acquired knowledge will enable the student to approach the differential diagnosis and therapy of leukemias and lymphomas.
• understand the biological basis of modern antitumoral therapy.
• design a correct assistance plan.
The lessons will treat selected issues in hemo-lympho-pathology and their clinical correlations. Emphasis will be given to the relevance of the tissue approach to the study of diseases and to the clinical use of lymphnode and bone marrow biopsy.
Generalities on nomenclature and classification will first be provided. A systematic discussion of lymphoadenitis/lymphoadenopathies will follow and their differential diagnosis with lymphomas. Tumors of lymphatic tissues, spleen and thymus will be examined in detail with etio-pathogenetic and clinical correlations. Finally, indications, techniques and concepts of histo-pathological interpretation of bone marrow biopsies will be discussed.
• Basic concepts of histopathological classification and nomenclature of hemo-lympho-proliferative diseases.
• Generalities on myelo-proliferative disorders.
• WHO classification of leukemias and lmphomas.
• Role of immunostains and molecular analysis techniques in the diagnosis and classification of leukemias and lymphomas.
• Differential diagnosis of lymphomas and lymphoadenitis/adnopathies.
• Molecular basis of leukemias and lymphomas.
• Leukemias and lymphomas of B and T precursor cells.
• Mature B cell lymphomas.
• Mature T cell lymphomas.
• Tumors of the spleen.
• Thymomas and other tumors of the thymus.
• Thymic hyperplasia and myastenia gravis.
• Bone marrow biopsy: indications, techniques and basic concepts of histo-pathological interpretation.
The results of the examination will contribute to the final evaluation of the integrated course.