The vertical column of icons on the far left reminds you of...
The vertical column of icons on the far left reminds you of the various stances available in the system. Medieval Italian and German longsword masters did us the favor of assigning vivid names to these positions, such as Boar's Tooth, Iron Gate, The Fool, Boar's Tooth, Window, and Woman's Guard. As you can see, we have translated these directly into icons.
(via CLANG by Subutai Corporation, Technical Update #2)
Turing Centenary Speech by Bruce Sterling
Turing Centenary Speech by Bruce Sterling:
So, let me talk a little bit about Turing's famous test for intelligence, the "imitation game." Everybody thinks they know what that is: it's a man talking to a computer, and the computer is trying to convince him that he's not a machine, he's a man. If he talks like a man and knows what a man knows, if he presents as a man, then we don't have to get into the dark metaphysical issues of what's going on in his black-box heart and spirit; the machine keeps up the façade, so therefore he's one of us, he's perfectly fine. That's the Turing Test as it's commonly described.
However, that's by no means what Turing actually says in his original paper on the subject. The real Turing imitation game is not about that process at all. It's about an entirely different process of gender politics and transvestism. It's about a machine imitating a woman.
This is a hypothetical example of The Kidney Failure Risk...
This is a hypothetical example of The Kidney Failure Risk Equation, a new tool designed for doctors and their patients with chronic kidney disease. It answers a common, often unspoken question that patients have: "What are my chances of requiring dialysis or a transplant?"
Using the Kidney Failure Risk Equation to Predict Progression to Kidney Failure Risk of progression to kidney failure requiring dialysis or transplantion: At 2 years: 14.8%. At 5 years: 41.2%. For patients with CKD Stage 4, we consider a 2 year risk of kidney failure of 0-10 % as low risk, 10-20 % as intermediate risk, and >20 % as high risk. About this calculator The kidney failure risk equation provides the 2 and 5 year probability of treated kidney failure (dialysis or transplantation) for a potential patient with CKD Stage 3 to 5. Predicted risks may differ from observed risks in clinical populations with lower and higher observed risks than the study population. This risk calculator was developed and validated in two independent populations of patients with CKD referred to nephrologists in Canada. Of the study population of 8,391, 57 % were men, 38 % had diabetes. Race was not reported, but most were probably white. Mean age, eGFR and urine ACR were 69, 33 ml/min/1.73m2 and 83 mg/g, respectively. The event rates of kidney failure in the two populations were 11 % and 24 % over a median follow up of 2 and 3 years. Determining the probability of kidney failure may be useful for patient and provider communication, triage and management of nephrology referrals and timing of dialysis access placement and living related kidney transplant. Prospective trials evaluating the utility of this instrument for clinical decision making have not yet been performed. Citation Tangri N, Stevens LA, Griffith J, et al. A predictive model for progression of chronic kidney disease to kidney failure. JAMA. 2011;305(15). DOI:10.001/jama.2011.451
How A Sudden Cardiac Arrest Survivor Handles the World Cup
How A Sudden Cardiac Arrest Survivor Handles the World Cup:
It's a story as incredible as it is incomprehensible: On 17 March, 2012, a world-class soccer player from England, Fabrice Muamba, has sudden cardiac arrest (SCA) on a European soccer field. The audience and remaining players stand stunned as CPR is initiated (video here). An automatic external defibrillator (AED) is applied to his chest. Two shocks from the AED are delivered on the field, another as he was carried to the ambulance nearly five minutes later, and 12 more shocks were delivered on the way to the hospital. None of them worked. Ultimately, 78 minutes of CPR were performed before the sixteenth shock miraculously restored sinus rhythm. He then underwent therapeutic hypothermia, and, just as incredibly, awakened neurologically intact some time later. He later undergoes implantation of an implantable cardiac defibrillator (ICD) as secondary prevention against future sudden cardiac arrest.
"I'm sorry to hear that the application you recently purchased is not functioning as expected. Having..."
"I'm sorry to hear that the application you recently purchased is not functioning as expected. Having had a similar experience before, I can certainly appreciate your concern. I know when I purchase something, I just want it to work."
- Mac App Store Customer Support, nailing it.
Baby Tropes
"Baby Tropes": term used by the medical residents to describe a patient's minimally elevated troponins.
Love Doximity.
Should diuretics be used to treat acute kidney injury?
Should diuretics be used to treat acute kidney injury?:
The bottom-line is that KDIGO went on a limb to make the assertion recommending against diuretics in AKI. The evidence is simply not there to make such a statement. The largest randomized trial is deeply flawed but even this showed minimal evidence for harm and a potential benefit. So, I will continue to use diuretics in the treatment of AKI until there is additional data to suggest otherwise.
Ajay Singh weighs in.
Why do patients with the nephrotic syndrome have edema?
Why do patients with the nephrotic syndrome have edema?:
The mechanism of edema formation in the nephrotic syndrome has long been a source of controversy. In this review, through the construct of Starling's forces, we examine the roles of albumin, intravascular volume, and neurohormones on edema formation and highlight the evolving literature on the role of primary sodium absorption in edema formation. We propose that a unifying mechanism of sodium retention is present in the nephrotic syndrome regardless of intravascular volume status and is due to the activation of epithelial sodium channel by serine proteases in the glomerular filtrate of nephrotic patients. Finally, we assert that mechanisms in addition to sodium retention are likely operant in the formation of nephrotic edema.
wolframalpha: The largest lake in the world is the Caspian Sea.
wolframalpha:
The largest lake in the world is the Caspian Sea.
"Watched #GoogleIO. This company is totally Doc Brown. In one corner, an automatic banana-peeler; in..."
"Watched #GoogleIO. This company is totally Doc Brown. In one corner, an automatic banana-peeler; in the other, A WORKING TIME MACHINE."
- @robinsloan
ikenbot: Milky Way over the city
ikenbot:
Milky Way over the city
"Listening to Let's Make Mistakes (55: Mike Learns How Not To Defame) http://t.co/yBml8sXd"
"Listening to Let's Make Mistakes (55: Mike Learns How Not To Defame) http://t.co/yBml8sXd"
- @joshuaschwimmer
Centrally reflective // #nyc #centralpark #bw #blackandwhite...
Centrally reflective // #nyc #centralpark #bw #blackandwhite #instagram #iphoneography #reflection
lydianoir, instagr.am
Roboto Glitter Lens, DC Film, No Flash, Taken with Hipstamatic
merlin: In Contexts Hey. You. Tune in to Mac Power Users next...
In Contexts
Hey. You. Tune in to Mac Power Users next week for the 3rd Annual VERY Long Episode About How Merlin Works. I think this one turned out really well.
As far as inscrutability such as the image above?
All will be revealed!
And, in the mean time, here are the two previous tours de force that David and Katie have kindly suffered. They're long, dense, and chockablock with manic and deeply nerdy workflow goodness:
MPU 023: Workflows with Merlin Mann « Mac Power Users (March, 2010) [MP3]
MPU 046: Workflows with Merlin Mann II « Mac Power Users (March, 2011) [MP3]
"Love the free fax service offered by @doximity. I just received a 106 page PDF of a patient's..."
"Love the free fax service offered by @doximity. I just received a 106 page PDF of a patient's previous medical records. Boom."
"if you visit from a linux machine orbitz automatically narrows your search to kaczynski-style cabins"
"if you visit from a linux machine orbitz automatically narrows your search to kaczynski-style cabins"
- @paleofuture
How to respond to problems
How to respond to problems:
(Four) Options for Responding to Any Problem:
(1) Solve the problem. Leave, get out of the situation for good, or change the situation.
(2) Feel better about the problem. Regulate your emotional response to the problem.
(3) Tolerate the problem. Accept and tolerate both the problem and your response to the problem.
(4) Stay miserable.
Taken with Instagram at Lenox Hill Hospital
Taken with Instagram at St Jean Baptiste Church
How New York Beat Crime
How New York Beat Crime:
The first nine years of New York City's crime decline were part of a much broader national trend, an overall drop of nearly 40 percent that started in the early 1990s and ended in 2000. It was the longest and largest nationwide crime drop in modern history. What sets New York apart from this general pattern is that its decline was twice as large as the national trend and lasted twice as long.
"Mac Power Users 91: Workflows with Merlin Mann III http://t.co/fjUTu9K0"
"Mac Power Users 91: Workflows with Merlin Mann III http://t.co/fjUTu9K0"
Med Student Rescues Body Part From Airport Security
Med Student Rescues Body Part From Airport Security:
No, said airline security, you can't take this bottle onboard. It exceeds the 100 milliliter limit; it's forbidden. We have just 16 hours to get it into her body. But wait, said professor Martin Birchall of Bristol University. This is a medical container. Inside is a trachea, a carefully constructed human windpipe, seeded with 60 million stem cells from a very sick woman in Barcelona. We have just 16 hours to get it into her body. We pre-arranged this. We have no record of your request, said the airline. You do have a record, said the professor. There's a woman in Barcelona right now who needs this, and we are running out of time. It took us five months to create this organ. It is the first of its kind. We must board this plane. Sometimes, leaps in medical science require an agreeable security guard, and on this day in 2008, he wasn't playing. The guard, then his supervisors, said no. Being larger than 100 milliliters, the bottle was categorically dangerous material. If Birchall insisted on boarding the plane, he would be arrested. Birchall had no Plan B. What was he to do? This is a true story.
"Docs, keep an eye out for the upcoming release of the new Doximity iPhone app. It's *awesome*."
"Docs, keep an eye out for the upcoming release of the new Doximity iPhone app. It's *awesome*."
Loco by Rudy Rucker and Bruce Sterling
Loco by Rudy Rucker and Bruce Sterling:
The house was a jumble of crazed debris—except for one shining treasure, the culmination of years of off-the-books black-budget research, a bubbling, green-lit aquarium-tank, with glassy little cells subdividing it like an uneasy high-rise—a tenement for leeches.
Eight or nine species of leeches. Careful Loco research had proved that leeches in particular excelled as plug-and-play biotech implants. Leeches were simple and rugged, they ran off human blood, and their boneless flesh could hold a fine payload of wetware programming. Plus, once you got used to the concept of interfacing with leeches, it didn't hurt all that much to stick them on.
"NYTimes: In Documents on Pain Drug, Signs of Doubt and Deception http://t.co/KunkqV8E"
"NYTimes: In Documents on Pain Drug, Signs of Doubt and Deception http://t.co/KunkqV8E"
Park Ave (Taken with Instagram at Lenox Hill Hospital)
"Photo: Dark Sky is the only weather app I know that can say, "It will rain for 9 more minutes."..."
"Photo: Dark Sky is the only weather app I know that can say, "It will rain for 9 more minutes." http://t.co/LAQp0Bto"
Dark Sky is the only weather app I know that can say, "It...
Dark Sky is the only weather app I know that can say, "It will rain for 9 more minutes."
The vertical column of icons on the far left remin...
This is a hypothetical example of The Kidney Failu...
How A Sudden Cardiac Arrest Survivor Handles the W...
(via CLANG by Subutai Corporation, Technical Updat...
"I'm sorry to hear that the application you recent...
Should diuretics be used to treat acute kidney inj...
Why do patients with the nephrotic syndrome have e...
wolframalpha: The largest lake in the world is the...
"Watched #GoogleIO. This company is totally Doc Br...
"Listening to Let's Make Mistakes (55: Mike Learns...
Centrally reflective // #nyc #centralpark #bw #bla...
Roboto Glitter Lens, DC Film, No Flash, Taken with...
merlin: In Contexts Hey. You. Tune in to Mac Power...
"Love the free fax service offered by @doximity. I...
"if you visit from a linux machine orbitz automati...
"Mac Power Users 91: Workflows with Merlin Mann II...
Med Student Rescues Body Part From Airport Securit...
"Docs, keep an eye out for the upcoming release of...
"NYTimes: In Documents on Pain Drug, Signs of Doub...
Park Ave (Taken with Instagram at Lenox Hill Hospi...
"Photo: Dark Sky is the only weather app I know th...
Dark Sky is the only weather app I know that can s...
With IFTTT's new support for Belkin's WeMo...
NPR Fresh Air: Fresh Air Master Roster (now bookma...
gerdfuturist: (via Times have changed)
ikenbot: Pizza Delivery Routes in Manhattan
"Lots of Doxers in NYC for #Pri-Med #FF to our gre...
lovagemetender: We got the beets!! At Maxwell's Fa...
Surface vs. iPad Introductions (by saymediainc)
"Reading about "COP" (the disease formally known a...
"Including the built-in Retina display, the new 20...
"Edible Fermentables" on NPR's Fresh Air #instacas...
"A nice news piece on virtual house calls starring...
"If your inbox is where you place things that you ...
Chrysler building, barely (Taken with Instagram)
"This is the dry story of a statistic. By which, I...
"Seriously, post op surgical drains are the worst....
"Hotel internet down. I scanned the network, found...
Vancouver Island Sunset | Flickr - Photo Sharing!f...
(via superbetter.com)
"Most websites play nicely with @Instapaper, but @...
behindawhitemask: A peek inside the newly re-desig...
"Nice graphic for why population medicine PSA does...
Likelihood ratios for hypovolemia (via The NNT).
"Definition of "Fiero" (via "Reality is Broken") h...
(via Kubrick Subway Photos)
lovagemetender: The first artichoke of the summer....
Black Death Discovered In Oregon
Does Medicaid Make You Sicker or Healthier?
(via Game of the week: Plague Inc.)
"NYTimes: You for Sale: Mapping, and Sharing, the ...
Friars' Club, Milton Berle Room
The first artichoke of the summer. At Maxwell's......
Cecily Loftus Lens, DC Film, No Flash, Taken with ...
Analyze This!
World Trade Center's coming up pretty. claytoncubi...
Support Site For Hospital Respirators Found Riddle...
Google Maps vs. Apple Maps: A Side-By-Side Compari...
WWDC Rene Ritchie, imore.com Apple's 2012 World Wi...
"NYC is the hot destination for startups, the way ...
Study: Away-facing strollers stress babies
New addition to the "Reference" folder: Dunno, a.....
Making yogurt Loftus Lens, DC Film, No Flash, Take...
Magic Hour, Park Ave Facing West Bettie XL Lens, A...
"Journal offers flat fee for 'all you can publish'...
Vintage Photos of Auto Accidents in Boston EDW Lyn...
"Fun with Likelihood Ratios" on Smart EM
"@joshuaschwimmer Enjoyed coming across your Tumbl...
parislemon: A spoiler yes, but it can't possible m...
"Pad in Motion rents iPads out to hospitalized pat...
(via Dark Sky)
"Dark Sky, a minimalist iPhone weather app that na...
"Kidney enthusiasts: please check out this List of...
"My colleague just discovered that a disease he de...
"NYTimes: To Cut Blood Pressure, Nerves Get a Jolt...
How the 'all-new' Foursquare is using big data to ...
Hi, Neal Stephenson here. My career as an author o...
Magic Hour, Battery Park City Lucas AB2 Lens, DC F...
That's me. Thanks, Jay. (via Visiting the Doctor.....
Lexington Ave (Taken with Instagram)
The Met from bus Lucifer VI Lens, Pistil Film, No ...
"The number of Apple-designed iPhone apps on my ho...
"I can verify that "thumbkissing" with the Pair iP...
"Someone should study whether holding a BlackBerry...