evidence: Data updated July 19, 2024 1,792 overdose deaths in 2022. That means 30 out of every 100,000 people in Wisconsin died of drug overdose. This was the highest the drug overdose death rate was in the state since data from 1999 became available. [...] In 2022, Wisconsin had a drug overdose death rate 2% lower than the US rate overall. The drug overdose death rate in Wisconsin increased in 20 of the last 23 years for which data is available. The overdose death rate has increased 66% since 2018 and increased 2.1 times since 2013. [...] The rise in drug overdose deaths nationally has been due to growing use of fentanyl and other synthetic opioids, however, this may vary by state. In 2022, fentanyl and other synthetic opioids were involved in more overdose deaths than any other drug, making up 73% of total overdose deaths in Wisconsin. The rates of drug overdose deaths involving cocaine increased 11.7 times between 1999 and 2022. For fentanyl and other synthetic opioids, the rates increased 59.7 times between 2000 and 2022.