evidence: AIDS-related illnesses, like tuberculosis and Kaposi’s sarcoma, are the main causes of death among people living with HIV with inadequate access to HIV care. Early in the HIV epidemic, it was proposed that poppers were linked to cases of Kaposi’s sarcoma in people with AIDS. However, research has debunked this hypothesis, showing that Kaposi’s sarcoma develops in people who are HIV-positive irrespective of poppers use and heavy poppers use isn’t linked to an increased risk of developing Kaposi’s sarcoma. In reality, Kaposi’s sarcoma is an opportunistic cancer that appears in people with weakened immune systems, such as those with advanced AIDS.