evidence: Causes and Risk Factors of Kaposi Sarcoma - People with a weakened immune system: This may be as a result of living with HIV or AIDS, undergoing an organ transplant, and being an older adult. [...] Kaposi sarcoma (KS) is a rare cancer caused by Kaposi sarcoma–associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV8), that often affects people with weakened immune systems. KS is characterized by lesions on the skin, but it can also affect other organs. While there's no cure for KS, it can be managed with treatments like HAART for HIV/AIDS-associated cases, chemotherapy, immunotherapy, surgery, radiation therapy, cryosurgery, and topical medications. Regular checkups and a healthy lifestyle will be helpful in managing your KS and improving your overall quality of life. [...] - What Causes Kaposi Sarcoma? American Cancer Society. April 19, 2018.