evidence: It is estimated that during 2000–2018, measles vaccines prevented 23.2 million deaths, but delays in routine vaccinations caused by the COVID-19 pandemic and crises in Ukraine, Ethiopia, Somalia, and Afghanistan have led to a nearly 80% worldwide rise in measles cases in 2022. [...] WHO estimates that there have been approximately 15 million direct or indirect deaths (also called "excess mortality") globally from January 2020 – December 2021 that were caused by the COVID-19 pandemic. South-East Asia, Europe, and the Americas accounted for 84% of the excess deaths. [...] As COVID-19 case numbers rise across the U.S. due to the highly transmissible omicron subvariants BA.4 and BA.5., FDA calls for Omicron-specific updates to COVID-19 vaccine boosters from Pfizer-BioNTech and Moderna in fall 2022.