evidence: U.S. Orders MILLIONS Of Smallpox Vaccines Amid Global Monkeypox Outbreak, Experts Say Remain Calm U.S. Orders MILLIONS Of Smallpox Vaccines Amid Global Monkeypox Outbreak, Experts Say Remain Calm. So far seven different countries are reporting confirmed or potential monkeypox cases. Monkeypox is very similar to smallpox and with the US having ordered so many vaccines many are wondering if the government knows something they aren't sharing.