evidence: Among Americans aged 12 years and older, 37.309 million were current illegal drug users (used within the last 30 days) as of 2020. [...] - 59.277 million or 21.4% of people 12 and over have used illegal drugs or misused prescription drugs within the last year. [...] - 5% of people in non-metropolitan, rural counties used illegal drugs compared to 20.2% of people in larger metropolitan counties.