evidence: There have been rare cases of serious adverse events reported with the COVID-19 vaccines. Previous studies have shown an increase in the risk of myocarditis and myopericarditis associated with mRNA vaccines including BNT162b2 (Pfizer-BioNTech) and mRNA-1273 (Moderna)8,11, and an increased risk of thrombotic and other rare cardiovascular events after the ChAdOx1 nCoV-19 vaccine (Oxford-AstraZeneca)12,13. There is also evidence of a range of other rare neurological complications14. However, the absolute risk of severe complications is low and needs to be assessed against the increased risks associated with SARS-CoV-2 infection if unvaccinated15,16. The balance of risk and benefit is particularly important to determine in younger people, due to the lower risk of COVID-19 hospitalisation and death in this age group17. [...] Relative incidence of death after COVID-19 vaccination