evidence: Addis Ababa, Ethiopia, 13 Aug 2024 – The Africa Centres for Disease Control and Prevention (Africa CDC) has officially declared the ongoing Mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017. [...] The declaration will enable the mobilization of resources across affected countries, unlocking essential funding, strengthening Risk Communication and Community Engagement (RCCE), boosting surveillance and laboratory testing efforts, and enhancing human resource capacities to respond effectively to Mpox through a One Health approach. [...] From May 2022 to July 2023, Mpox was declared a Public Health Emergency of International Concern (PHEIC) by the WHO. However, Africa did not receive the support it urgently needed during this period. As global cases began to decline, the escalating numbers in Africa were largely ignored. Dr. Kaseya emphasized the need for a change in approach: "We urge our international partners to seize this moment to act differently and collaborate closely with Africa CDC to provide the necessary support to our Member States."