evidence: The important herbal pair for the treatment of COVID-19 and its possible mechanisms - PMID: 33658066 - PMCID: PMC7927769 - DOI: 10.1186/s13020-021-00427-0 [...] Conclusions: There were 32 association rules in the TCM prescriptions recommended by experts for COVID-19. The combination of ACV and EAS was the most important herbal pair for the treatment of COVID-19. AE might have therapeutic effects against COVID-19 by affecting the inflammatory and immune responses, cell apoptosis, hypoxia damage and other pathological processes through multiple components, targets and pathways.