evidence: Female breast cancer represents 15.5% of all new cancer cases in the U.S. [...] Female breast cancer is most common in middle-aged and older women. Although rare, men can develop breast cancer as well. The rate of new cases of female breast cancer was 129.4 per 100,000 women per year based on 2017–2021 cases, age-adjusted. [...] Using statistical models for analysis, age-adjusted rates for new female breast cancer cases have been rising on average 1.0% each year over 2012–2021. Age-adjusted death rates have been falling on average 1.2% each year over 2013–2022. 5-year relative survival trends are shown below.