evidence: Manuka Honey Can Kill Every Kind Of Bacteria You Throw At It (Even The Superbugs!) [...] Clinical trials have found that manuka honey can effectively eradicate more than 250 clinical strains of bacteria, including certain antibiotic-resistant varieties.4 Manuka has an exclusive ingredient with antimicrobial qualities called the Unique Manuka Factor (UMF) that give it extraordinary antibacterial activity. Honey releases hydrogen peroxide through an enzymatic process that gives it its antiseptic qualities, but active manuka honey contains a "special something" that makes it far superior to other types of honey when it comes to killing off bacteria.