evidence: The increased prevalence of cancer pain and the impact of the opioid epidemic on cancer pain management—and on managing chronic pain in general—have sparked renewed interest in developing new, nonaddictive pain medications as well as nondrug approaches for managing chronic pain. [...] There’s also a keen interest in using cannabinoids—chemicals found in marijuana—to treat cancer-induced bone pain and some other types of cancer pain, Dr. O’Mara said, although, so far, research in this area is limited to studies in animal models. For example, work by Todd Vanderah, Ph.D., of the University of Arizona, has shown that cannabinoids can reduce severe bone pain and also suppress cancer growth and reduce bone loss in a mouse model of breast cancer that has spread to the bone.