evidence: Is there enough monkeypox vaccine to go around? Maybe yes, more likely no [...] In theory there are at least three existing vaccines that could be used to protect people from monkeypox. But one is not recommended for widespread use. It's a vaccine against smallpox called ACAM2000 that the United States' Food and Drug Administration has now made available for use against monkeypox under what's called an "investigational" protocol; in rare cases it may cause dangerous side effects such as swelling of the heart. [...] The inequity is particularly stark in Africa, where monkeypox had been endemic in several countries for years before the current outbreak. For now, at least, official case numbers remain relatively low in African countries. Still that could always change – or the official counts could be missing cases – notes WHO Africa's Dr. Phiona Atuhebwe. So the lack of availability of monkeypox vaccine is galling.