evidence: Based on what CDC knows now, existing tests used to detect and medications used to treat COVID-19 appear to be effective with this variant. BA.2.86 may be more capable of causing infection in people who have previously had COVID-19 or who have received COVID-19 vaccines. Scientists are evaluating the effectiveness of the forthcoming, updated COVID-19 vaccine. CDC’s current assessment is that this updated vaccine will be effective at reducing severe disease and hospitalization. At this point, there is no evidence that this variant is causing more severe illness. That assessment may change as additional scientific data are developed. CDC will share more as we know more. [...] 9/20/2023: Clarification on BA.2.86 risk assessment posted on 8/23/2023. The first risk assessment CDC released on BA.2.86 included the following sentence: "BA.2.86 may be more capable of causing infection in people who have previously had COVID-19 or who have received COVID-19 vaccines." The intent of this sentence was to raise the possibility that BA.2.86 might be more capable of causing infection compared with other variants currently circulating, but this sentence has been misinterpreted by some. Vaccination remains the best available protection against the most severe outcomes of COVID-19, including hospitalization and death. COVID-19 vaccines also reduce the chance of having Long COVID. Since this webpage was originally posted, laboratory data have become available that suggest existing antibodies from previous COVID-19 vaccines and COVID-19 infection provide protection against this variant similar to other circulating variants and that updated COVID-19 vaccines are expected to provide similar protection as other circulating variants.