evidence: - Restoring normal blood glucose concentrations - Stopping or controlling weight loss - Stopping or minimizing signs of increased thirst and urination - Avoiding inappropriately low blood sugar due to treatment (hypoglycemia) These goals are traditionally achieved through a combination of insulin and dietary therapy, though new oral medications may be a good treatment option for some cats. Treatment options should be discussed with the veterinarian based on each individual cat. [...] In 2023, a new class of medications that are administered by mouth once daily was approved for the treatment of feline diabetes,. These medications, known as SGLT2 (sodium-glucose cotransporter 2) inhibitors, lower the concentration of glucose in the blood by increasing the amount excreted through the kidneys. These medications help improve the clinical signs of diabetes by lowering insulin resistance and reducing damage to the pancreas, allowing the cat to produce more of its own insulin. Because these treatments rely on the cat making at least some insulin on its own, it is not appropriate for every patient, and this treatment should be discussed with a veterinarian before starting. SGLT2 inhibitors are approved for treatment of newly-diagnosed diabetic cats who are otherwise healthy and have not been previously treated with any injectable insulin, and studies have shown these medications to be more than 80% effective at improving blood glucose control in appropriate patients.