evidence: Table 1 Opportunities and limitations of current SARS-CoV and SARS-CoV-2 model systems [...] Work in the authors laboratory was supported by the Swiss National Science Foundation (SNF grants #173085, 196644, 182880) and the Federal Ministry of Education and Research, Germany (BMBF; grant RAPID, #01KI1723A). [...] Ram Lal Swagat Shrestha