evidence: FULL CLAIM: "No childhood vaccine has ever been through a double blind placebo controlled trial."; childhood vaccine schedules haven't been tested properly The claim that no childhood vaccine has ever been tested against a placebo in a double-blind, randomized trial commonly crops up in anti-vaccine content. One example of this claim can be seen in this Instagram post. Prominent figures in the anti-vaccine community, including U.S. presidential candidate Robert F. Kennedy Jr. and television producer Del Bigtree, have also made this claim before. [...] And a search on PubMed, a repository of studies in health and medicine that is maintained by the U.S. Library of Medicine, will also turn up multiple studies showing that several vaccines on the childhood vaccination schedule have indeed been tested in double-blind, saline placebo-controlled randomized trials.