evidence: This ongoing phase 3 trial involving 583 high-risk patients with symptomatic COVID-19 5 days or less after symptom onset, showed a relative risk reduction for hospitalization or death of 85% (97.24% CI, 44-96). Three patients in the treated group as compared with 21 patients in the placebo group had disease progression leading to hospitalization or death. [...] HHS in coordination with NIH and Operation Warp Speed has just launched a new website entitled Combat COVID to pull together the most current information for people of all groups, races, ethnicities and backgrounds who want to get involved in fighting the pandemic. You can find resources to join a prevention trial, locate treatment trials if you are infected, find places to donate plasma if you have recovered from an infection, or find treatment options or trials if you are a physician. [...] Vaccines: Previous research on SARS-CoV-1 and MERS has led to more rapid development of potential vaccines against SARS-CoV-2. As part of Operation Warp Speed, the federal government is funding three vaccine candidates for Phase 3 trials this summer: mRNA-1273 developed by National Institute of Allergy and Infectious Diseases (NIAID) scientists and collaborators at Moderna, which directs cells to express a viral protein to elicit an immune response, starting in July; AZD1222, which uses a chimpanzee adenovirus vector to deliver a SARS-CoV-2 protein, being developed by Oxford’s Jenner Institute in partnership with AstraZeneca, starting in August; and BNT162, an mRNA-based vaccine being developed by BioNTech and Pfizer, which will start in September. A nice table and summary can be found in this article.