evidence: Childhood vaccination helps to reduce the risk of potentially serious diseases, including measles and polio. Large-scale, reputable studies have not found a greater incidence of adverse health outcomes in vaccinated children compared to unvaccinated children. Ingredients in childhood vaccines aren’t present in toxic amounts. The American Academy of Pediatricians recommends on-time routine immunization of all children and adolescents according to the CDC’s Recommended Child and Adolescent Immunization Schedule.