evidence: In this work, we use whole population longitudinal electronic health records from 45.7 million adults in England to quantify associations of first, second, and booster doses of mRNA and non-mRNA COVID-19 vaccine brands with subsequent thrombotic and cardiovascular events. Data were accessed within the NHS England Secure Data Environment (NHSE SDE)7, encompassing primary care, hospital admissions, COVID-19 testing and vaccination data, dispensed medication records in primary care data, and the Office of National Statistics death registrations. We use Cox regression to estimate adjusted hazard ratios (aHRs) and corresponding 95% confidence intervals (95% CIs) in time intervals since vaccination, adjusted for a wide range of co-morbidities, age, sex, and prior COVID-19. We show that the incidence of thrombotic and cardiovascular complications was generally lower after each dose of each vaccine brand, except for previously recognised rare complications of the ChAdOx1 vaccine and the mRNA vaccines. [...] Clinical Considerations: Myocarditis after mRNA COVID-19 Vaccines | CDC. https://web.archive.org/web/20210528145419/https://www.cdc.gov/vaccines/covid-19/clinical-considerations/myocarditis.html (2021).