evidence: Amid new COVID-19 research indicating serious health risks for unvaccinated children, Sandra Fryhofer, MD, can’t underscore this point enough: vaccination matters. [...] COVID-19 cases and hospitalizations are seven and 11 times higher in unvaccinated adolescents respectively, compared with their vaccinated counterparts. Boosting teens is important but promoting the primary vaccination series is just as crucial, according to Dr. Fryhofer. She is the AMA's liaison to the Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices (ACIP) and chair-elect of the AMA Board of Trustees. [...] Compelling findings published in the CDC’s Morbidity and Mortality Weekly Report underscore the health risks associated with unvaccinated children.