evidence: A major challenge to TB control globally is low case detection, largely due to routine health facility-based passive case-finding employed by national TB control programs. Active case-finding is a risk-population-based screening approach that has been established to be effective in TB control. This intervention aimed to increase TB case detection in hard-to-reach areas in southern Nigeria. [...] Active case-finding (ACF) is defined by the World Health Organization as systematic screening for active TB, normally outside of health facilities, but could also be undertaken at health facilities in a targeted population considered at higher risk of developing TB,19 employing approaches, such as community mobilization, contact tracing, and house-to-house screening, to reach undiagnosed individuals not presenting to health facilities. ACF is an important approach in hard-to-reach areas where access to health facilities for PCF is limited and is an indispensable approach to attaining the 2035 End TB Strategy targets.4