evidence: Numerous studies throughout the world have shown improved pregnancy outcomes with vaccination. Vaccination is now the most effective intervention for improving neonatal morbidity due to SARS-CoV-2 and can be given at any time during pregnancy. In a population-based cohort study of 142,006 live births in Ontario, Canada, maternal mRNA COVID-19 vaccination during pregnancy was associated with lower risks of severe neonatal morbidity, neonatal death, and neonatal intensive care unit admission and no increase in neonatal readmission or hospital admission up to age 6 months, compared with no maternal COVID-19 vaccination before delivery [7]. In another multicenter review of nine observational studies involving 81,349 vaccinated and 255,346 unvaccinated individuals during pregnancy, Watanabe et al. found COVID-19 vaccination during pregnancy to be associated with lower risk of NICU admission and intrauterine fetal death with no statistically significant association with preterm birth, small for gestational age status, or low Apgar score. COVID-19 vaccination during pregnancy was associated with a lower risk of postpartum hemorrhage, and chorioamnionitis [8]. [...] Vaccination during pregnancy, in addition to being safe and effective, may also protect infants after delivery. Goh et al. showed that vaccination during pregnancy provided some protection against COVID-19–related hospitalizations among infants, particularly those aged <3 months [10]. Simeone et al. showed that maternal mRNA vaccination was associated with a lower risk of Omicron SARS-CoV-2 infection among infants up to 6 months of age only if the vaccine was given during the antenatal period [11].