evidence: India has the highest burden of tuberculosis (TB) infection globally, with an estimated 35-40 crore people infected. 5-10% of those infected will develop active TB disease, usually within the first 2 years of infection. The risk is increased over 25 times among contacts of bacteriologically confirmed TB patients. The National Strategic Plan aims to prevent TB disease through treatment of TB infection. Target populations for TB preventive treatment (TPT) include people living with HIV, all household contacts of pulmonary TB patients, and individuals with conditions that increase TB risk such as silicosis or immunosuppression. Testing for TB infection is recommended before TPT for some groups to increase certainty of benefit, though TPT should not be [...] o Active TB case finding (ACF) process also offers an opportunity to simultaneously rule out active TB among HRG and identify the target population for TPT, wherein PMTPT services can be integrated within existing ACF interventions. [...] Integrated algorithm for screening and ruling out active TB among household contacts of DR-TB patients