evidence: The objective of this cross-sectional study was to determine the prevalence, intensity of infection and geographical distribution of schistosome and STH infections among primary school children in Mbita and surrounding Islands of Lake Victoria (Mfangano, Ringiti, Rusinga and Takawiri) in western Kenya. Understanding the prevalence and distribution of infection in such endemic areas not only serves as a guide in pin-pointing high-risk populations and transmission sites which is critical in developing sound and targeted control interventions to reduce the burden of these infections, but also to provide a robust baseline to monitor program impact. The study was conducted in Mbita district, which borders Lake Victoria in western Kenya, between February-March 2012. In line with the new Kenyan constitution, Mbita district is now part of Homabay County. Mbita is located at latitude (0°25’S) and longitude (34°12'E), has 3 main divisions (Mbita, Lambwe & Mfangano) and has a population estimated at 111,409 [11]. Its associated Islands include Mfangano, Remba, Ringiti, Rusinga and Takawiri. Rainfall pattern in Mbita is seasonally bimodal, with the heaviest rains falling from March through May and the shorter rainy season occurring between September and December. On the highlands the rainfall ranges between 800-1900 mm per annum; in lower areas, it is between 800-1200 mm each year. The mean minimum temperature is 15°C while the mean maximum temperature is 30°C.