evidence: Are wall geckos poisonous? This is a question that many homeowners ask, and rightly so. The good news is that wall geckos are not poisonous. In fact, they are actually quite harmless creatures. So if your gecko escapes or you find a wall gecko in your home, there is no need to worry about them harming anyone. [...] Geckos are one of the most beloved reptiles in the world, and for good reason. They’re small, harmless, entertaining to watch, and best of all – they’re not poisonous to humans or animals. [...] Some geckos may carry salmonella or other pathogens which could cause illness if ingested. In addition, smaller geckos may also become frightened easily and lash out when approached; this could lead to bites which could be potentially dangerous as well. To ensure the safety of your children or pet animals, it’s best to keep them away from wall geckos.