evidence: The study was assembled over seven years by a consortium of more than 80 researchers from 16 nations. It appears today in the journal Science. [...] The giant caveat: Earth system sensitivity describes climate changes over hundreds of thousands of years, not the decades and centuries that are immediately relevant to humans. The authors say that over long periods, increases in temperature may emerge from intertwined Earth processes that go beyond the immediate greenhouse effect created by CO2 in the air. These include melting of polar ice sheets, which would reduce the Earth’s ability to reflect solar energy; changes in terrestrial plant cover; and changes in clouds and atmospheric aerosols that could either heighten or lower temperatures. [...] The researchers confirmed the long-held belief that the hottest period was about 50 million years ago, when CO2 spiked to as much as 1,600 ppm, and temperatures were as much as 12 degrees C higher than today. But by around 34 million years ago, CO2 had dropped enough that the present-day Antarctic ice sheet began developing. With some ups and downs, this was followed by a further long-term CO2 decline, during which the ancestors of many modern-day plants and animals evolved. This suggests, the paper’s authors say, that variations in CO2 affect not only climate, but ecosystems.