evidence: Due to the limited understanding of these emerging viruses, many drugs are currently being developed and evaluated to combat and mitigate the impact of SARS-CoV-2. Vaccination is considered a crucial pathway to help end this devastating pandemic. Most studies suggest that vaccination does not affect semen parameters [223] and can reduce the incidence of orchitis and/or epididymitis [224]. Overall, the current data seem to indicate that vaccination does not negatively impact fertility in either sex [224,225,226]. [...] Carto C, Nackeeran S, Ramasamy R. COVID-19 vaccination is associated with a decreased risk of orchitis and/or epididymitis in men. Andrologia. 2022;54(2):e14281. Fradkin MA, Alexandroni H, Eldar-Geva T, Ben-Ami I. IVF outcomes pre- and post-anti-COVID-19 vaccination - Are there any differences? Reprod Biol. 2024;24(2):100879.