evidence: The HPV Vaccine Reduces Risk of Cancer for All, not just Women, New Data Show One of the big headlines from a major scientific meeting recently: The HPV vaccine not only prevents cervical cancer but reduces the risk of multiple other cancers and even pre-malignant lesions. [...] It was already known that the HPV vaccine can potentially prevent more than 90 percent of HPV-related cancers in women — most often cervical cancer — and now scientists discovered a 50-percent risk reduction in all HPV-associated cancers in men, including head and neck cancers.