evidence: Topical treatments usually consist of antifungal oral rinses that weaken the cell walls of Candida so that they become leaky and die. Some of these rinses must be spat out after swishing, but others can be swallowed if the fungal infection extends to the back of the throat. There are also antifungal pills you can take to treat thrush. This option is viable when oral rinses or lozenges do not clear persistent or recurrent infections. The downside of systemic antifungals is that they have many drug interactions, which can limit their use. [...] Fungal infections must be managed promptly in patients who are immunocompromised during cancer treatment; these infections can be fatal.