evidence: People with weak immune systems can take steps to reduce their risk. It's especially important for those who live in areas where these fungi are found. [...] Healthcare providers treat fungal meningitis with high-dose antifungal medicines, often given directly into a vein through an IV. After that, people also need to take antifungal medicines by mouth. The total length of treatment depends on each person's immune system and the type of fungus causing the infection. Treatment is often longer for people with weak immune systems.