evidence: Toxoplasma gondii is a common parasitic infection in cats but is often asymptomatic, although acute or disseminated infections may affect the eyes, brain or other systems, with clindamycin being the preferred treatment. Conclusive diagnosis requires either IgM or paired IgG titer serology. As a zoonotic disease, toxoplasmosis is especially dangerous for pregnant or immunocompromised individuals, but cat ownership is not a significant risk for human infection; rather, ingestion of oocyst-contaminated food or water, or tissue cysts in undercooked meat, are a much more real threat. Fecal contamination of soil and water also presents a serious health risk. Simple hygiene strategies can prevent transmission of T. gondii and, for cat owners, keeping their pets indoors (if possible) and daily cleaning of the litter box greatly mitigates the zoonotic risk.