evidence: Among 3,242,649 patients aged ≥18 years with documented height and weight who received ED or inpatient care in 2020, a total of 148,494 (4.6%) had ICD-10-CM codes indicating a diagnosis of COVID-19 (Table). Among 71,491 patients hospitalized with COVID-19 (48.1% of all COVID-19 patients), 34,896 (48.8%) required ICU admission, 9,525 (13.3%) required invasive mechanical ventilation, and 8,348 (11.7%) died. Approximately 1.8% of patients had underweight, 28.3% had overweight, and 50.8% had obesity. Compared with the total PHD-SR cohort, patients with COVID-19–associated illness were older (median age of 55 years versus 49 years) and had a higher crude prevalence of obesity (50.8% versus 43.1%). [...] †† Patients who were hospitalized were defined as those with a reported hospital inpatient encounter, patients who were admitted to an ICU or who received invasive mechanical ventilation were determined by patient billing records, and patients who died were determined by patient discharge records indicating that death that occurred in the hospital or in hospice care. [...] Suggested citation for this article: Kompaniyets L, Goodman AB, Belay B, et al. Body Mass Index and Risk for COVID-19–Related Hospitalization, Intensive Care Unit Admission, Invasive Mechanical Ventilation, and Death — United States, March–December 2020. MMWR Morb Mortal Wkly Rep 2021;70:355–361. DOI: http://dx.doi.org/10.15585/mmwr.mm7010e4.