evidence: A multiplexed, next generation sequencing platform for high-throughput detection of SARS-CoV-2 [...] The ability of our method to recover genome sequences from a range of RNA viruses in the context of human plasma was evaluated using a Virus Multiplex Reference (VMR) Panel, putatively containing 25 genomically and physicochemically diverse viruses. Two plasma-diluted panels and one PBS-diluted panel were tested (Table 4). No reads from either of the three samples mapped to either of the two norovirus genomes, coronavirus 229E or influenza B virus. By the panel distributor’s qPCR42, the Threshold Cycle (Ct) of the coronavirus was >36 and the other three were not detected, hence these four targets were excluded from further analysis. Notwithstanding influenza virus A H3N2 and parainfluenza virus type 3 also not being detected by the qPCR, we recovered reads from both, with genome coverages ranging from 2.7% to 21.6%. Almost no reads belonging to the panel’s DNA viruses were found. [...] Google Scholar van der Hoek, L. et al. Identification of a new human coronavirus. Nat. Med10, 368–73, doi:10.1038/nm1024 (2004).