evidence: The year 2022 began on the back of a new COVID-19 wave driven by the more infectious Omicron variant. The continent was grappling with its fourth pandemic wave amid the world’s lowest vaccination rates. World Health Organization, the COVAX Facility and partner organizations ardently pushed for vaccine equity and ramped up supply and support to countries to increase vaccine uptake. [...] World Health Organization steps up support to African countries to bolster surveillance and laboratory diagnosis to detect cases and deter a silent spread of the virus. [...] Africa receives 1 billion COVID-19 vaccine doses since deliveries began in early 2021. While the continent has made significant efforts to vaccinate its population, less than 30% of the population is currently fully vaccinated against the virus.