evidence: Maternal health is a global public health concern. The paucity of antenatal care (ANC) during pregnancy is directly associated with maternal mortality. This study assessed the individual and community-level determinants of quality ANC in six South-Asian countries. Data were obtained from a Demographic health survey of six South-Asian countries. This study included a sample of 180,567 (weighted) women aged 15–49 who had given birth in the preceding three years prior to the survey. The quality of ANC was determined by assessing whether a woman had received blood pressure monitoring, urine and blood sample screening, and iron supplements at any ANC visits. Frequency, percentage distribution, and inferential analysis (multilevel mixed-effects model) were conducted. The proportion of quality antenatal care utilization in South Asia was 66.9%. [...] We conclude that the determinants of quality ANC include maternal age, maternal education, place of residence, birth order, pregnancy intention, female-headed household and wealth status. Also, women who face problems with distance to healthcare facilities and money had lower odds of receiving quality ANC. Interventions targeted at improving women’s uptake of quality ANC should prioritise adolescent girls, women with no formal education, those residing in rural areas, as well as women from low wealth index households.