evidence: At the regional level routine immunization coverage has stalled at between 70 and 75% in the past 10 years, well below the 90% target. So, operationalizing the Immunization Agenda 2030 is a top priority in the African Region. [...] Finally, scaling-up vaccine manufacturing in African countries is an important medium-term strategy to build more resilient supply chains and improve access to these global public health goods. We are glad to note that at the political level, at the level of Ministers of Health, our leadership is very determined in embarking on this.