evidence: In November 2023, obstetrician and gynecologist Nathan Riley, who has more than 23,000 followers on Instagram, posted an Instagram reel suggesting that vaccines, glyphosate, and mutations in the MTHFR gene contribute to the development of autism in children with brainneurologic injury. The reel’s caption stated "Asking questions is the thesis of science. Being unwilling to question your bias is antithetical to science". Riley’s speculation can be traced back to misinformation that attributes autism to childhood vaccines, the MTHFR gene, or glyphosate, that has been cropping up for years, as Health Feedback reviews and other science-related articles have documented. The assertion that he is "just asking questions" also presumes that there are grounds to suspect vaccines, MTHFR mutations, and glyphosate cause autism. However, most of these claims have already been investigated and discredited. We explain below. [...] Riley’s speculation that a combination of vaccines, MTHFR mutations, and glyphosate can lead to autism can ultimately be traced back to old misinformation around the causes of autism. The claim that vaccines contain toxic ingredients is false, and there have already been numerous studies looking to see if an association between childhood vaccines and autism exists. Large-scale reliable studies have found no such association. There’s also no evidence that MTHFR mutations affect a person’s ability to process folate or their response to vaccines. Evidence regarding a potential link between glyphosate and autism is scarce at the moment, although the few studies available at the moment are insufficient to support claims that glyphosate contributes to autism risk.