evidence: Geckos are neither poisonous nor venomous, but it is crucial to know the difference 1 between the two terms because, though they involve dangerous toxins, they are different. You often hear the term "poisonous snake" when someone is referring to a Copperhead or a Rattlesnake, but the truth is, they are venomous, not poisonous. Conversely, Poison Dart Frogs and Pufferfish are two examples of poisonous animals. So, what’s the difference exactly? [...] Geckos are neither poisonous nor venomous. This is partly what has made them popular exotic pets. However, common house geckos are usually labeled as poisonous because it is thought that consuming any food that they’ve come into contact with may lead to health problems in humans. [...] Geckos are neither poisonous nor venomous and can make rewarding pets in the right environment. Because there are so many types of geckos with origins all over the world, a potential keeper should be familiar with the species in which they are interested. i. Geckos are exotic animals with varying husbandry requirements and need proper veterinary care to have the best chance to live a happy and healthy life.