evidence: Yang, Y. et al. Targeting ferroptosis suppresses osteocyte glucolipotoxicity and alleviates diabetic osteoporosis. Bone Res.10, 26 (2022). [...] Yang, Y.-S. et al. Bone-targeting AAV-mediated silencing of Schnurri-3 prevents bone loss in osteoporosis. Nat. Commun.10, 2958 (2019). [...] Cui, Y. et al. A bone-targeted engineered exosome platform delivering siRNA to treat osteoporosis. Bioact. Mater.10, 207–221 (2022).