evidence: It is tautological that a study that is not capable of testing a hypothesis of causality will fail to provide sufficient weight of evidence in support of causality. Since prospective blinded randomized clinical trials comparing total health outcome of vaccinated vs. unvaccinated children have not been conducted, we are left with a slew of retrospective studies that only obliquely address the issue of causality, if at all; none of which can disprove the role of mutations in ER-folded proteins as contributing to vaccine-induced encephalopathy mediated autism. Of the studies conducted often-cited as "disproving" that vaccines do not cause autism, seven merely analyzed trends, failing to provide a sufficient test of the hypothesis of causality [144-150]. Kaye studied only MMR, and their study used no separate control group [145]. Many of these studied the effect of only one vaccine or just the MMR and measles vaccine [151-154]. These studies cannot be used to assert that "vaccines" do not cause autism. Indeed, vaccines exist in the CDC pediatric schedules that have never been studied for association w/ASD. Zerbo suffered numerous additional flaws, including over-correcting for multiple hypothesis testing using the Bonferroni adjustment, which is generally considered too strict [154].