evidence: Bern, 21.05.2021 - 2,269 reports of suspected adverse reactions to COVID-19 vaccines in Switzerland evaluated: Up to 18 May 2021, Swissmedic evaluated 2,269 reports on suspected adverse drug reactions (ADR) to COVID-19 vaccinations in Switzerland. The reports corroborate the side effects profile identified during the authorisation studies and described in the medicinal product information, and do not alter the positive ratio of benefits to risks of the two mRNA vaccines used. [...] The reports of adverse reactions received and analysed to date do not alter the positive benefit-risk profile of the COVID-19 vaccines used in Switzerland. Any pointers to as yet unknown safety problems based on reports from within Switzerland or from abroad will be thoroughly investigated. Thus, for example, some very rare reports from around the world of immune thrombocytopenia (ITP) or inflammation of the heart muscle (myocarditis) are being analysed further. In evaluating the safety aspects of the COVID-19 vaccines, Swissmedic is also in close and regular contact with other international drug regulatory agencies. As soon as valid findings are available on possible risks, we will provide information about these and about any measures that can be taken to alleviate them.