evidence: Ivermectin did not have any significant effect on outcomes of COVID-19 patients and as WHO recommends, use of ivermectin should be limited to clinical trials. [...] And despite the fact that WHO recommends that ivermectin must be used solely in clinical trials to treat COVID-19, according to recently published studies, the misuse of this medication and a significant number of ivermectin prescriptions have been widely documented, particularly in the United States [9, 10].