evidence: The decreases in life expectancy were not experienced equally among all New Yorkers. The largest decreases were among Black and Latino New Yorkers. For Black New Yorkers, the pandemic worsened existing disparities. [...] Chronic and diet-related diseases, such as heart disease, stroke, diabetes and screenable cancers, continue to be leading causes of death across all racial and ethnic groups in NYC. In 2021, more than 30,000 New Yorkers died from these conditions, one-third of which were due to cancer. [...] More than 20,400 NYC residents died from COVID-19 in 2020, followed by more than 7,700 NYC residents in 2021. Age-adjusted COVID-19 death rates in 2020 were roughly twice as high among Black and Latino New Yorkers compared with White and Asian New Yorkers.