query: subclass_of trailhead
supports: Mississippi is a state in the southern region of the United States, with part of its southern border formed by the Gulf of Mexico. Its western border is formed by the Mississippi River. Apoptosis (from Ancient Greek  "falling off") is a process of programmed cell death that occurs in multicellular organisms. Biochemical events lead to characteristic cell changes (morphology) and death. These changes include blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation, chromosomal DNA fragmentation, and global mRNA decay. Between 50 and 70 billion cells die each day due to apoptosis in the average human adult. For an average child between the ages of 8 and 14, approximately 20 billion to 30 billion cells die a day. Kansas City (often abbreviated as "KCK" to differentiate it from its adjacent namesake, Kansas City, Missouri) is the third-largest city in the state of Kansas, the county seat of Wyandotte County, and the third-largest city of the Kansas City metropolitan area. It is part of a consolidated city-county government known as the "Unified Government". Wyandotte County also includes the independent cities of Bonner Springs and Edwardsville. As of the 2010 census, the city had a population of 145,786 residents. It is situated at Kaw Point, which is the junction of the Missouri and Kansas rivers. The word railhead is a railway term with two distinct meanings, depending upon its context. Kansas is a U.S. state located in the Midwestern United States. Its capital is Topeka and its largest city is Wichita. Kansas is named after the Kansa Native American tribe, which inhabited the area. The tribe's name (natively "") is often said to mean "people of the wind" or "people of the south wind", although this was probably not the term's original meaning. For thousands of years, what is now Kansas was home to numerous and diverse Native American tribes. Tribes in the eastern part of the state generally lived in villages along the river valleys. Tribes in the western part of the state were semi-nomadic and hunted large herds of bison. Texas is the second largest state in the United States by both area and population. Geographically located in the south central part of the country, Texas shares borders with the U.S. states of Louisiana to the east, Arkansas to the northeast, Oklahoma to the north, New Mexico to the west, and the Mexican states of Chihuahua, Coahuila, Nuevo León, and Tamaulipas to the southwest, while the Gulf of Mexico is to the southeast. The Chisholm Trail was a trail used in the post-Civil War era to drive cattle overland, from ranches in Texas to Kansas railheads. The portion of the trail marked by Jesse Chisholm went from his southern trading post near the Red River, to his northern trading post near Kansas City, Kansas. Natchez is the county seat and only city of Adams County, Mississippi, United States. Natchez has a total population of 15,792 (as of the 2010 census). Located on the Mississippi River across from Vidalia in Concordia Parish, Louisiana, Natchez was a prominent city in the antebellum years, a center of cotton planters and Mississippi River trade.  The Natchez Trace, also known as the "Old Natchez Trace", is a historic forest trail within the United States which extends roughly from Natchez, Mississippi, to Nashville, Tennessee, linking the Cumberland, Tennessee, and Mississippi Rivers. Nashville is the capital of the U.S. state of Tennessee and the county seat of Davidson County. It is located on the Cumberland River in the north central part of the state. The city is a center for the music, healthcare, publishing, banking and transportation industries, and home to numerous colleges and universities. Reflecting the city's position in state government, Nashville is home to the Tennessee Supreme Court's courthouse for Middle Tennessee. It is known as a center of the country music industry, earning it the nickname "Music City U.S.A." A trading post or trading station was a place or establishment where the trading of goods took place; the term is generally used, in modern parlance, in reference to such establishments in historic Northern America, although the practice long predates that continent's colonization by Europeans. The preferred travel route to a trading post or between trading posts, was known as a trade route. Proteins (or ) are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific three-dimensional structure that determines its activity. Cell biology (formerly called cytology, from the Greek , "kytos", "vessel") is a branch of biology that studies the different structures and functions of the cell and focuses mainly on the idea of the cell as the basic unit of life. Cell biology explains the structure, organization of the organelles they contain, their physiological properties, metabolic processes, signaling pathways , life cycle, and interactions with their environment. This is done both on a microscopic and molecular level as it encompasses prokaryotic cells and eukaryotic cells. Knowing the components of cells and how cells work is fundamental to all biological sciences; it is also essential for research in bio-medical fields such as cancer, and other diseases. Research in cell biology is closely related to genetics, biochemistry, molecular biology, immunology, and developmental biology. In the field of cell biology, TNF-related apoptosis-inducing ligand (TRAIL), is a protein functioning as a ligand that induces the process of cell death called apoptosis. Jesse Chisholm (circa 1805 - March 4, 1868) was a mixed blood Cherokee fur trader. His name is most famous because of the namesake cattle trail, which he originally scouted and developed to supply his various trading posts among the Plains Indians in what is now western Oklahoma. Although Chisholm died before the heyday of the Texas-to-Kansas cattle drives, he was nevertheless a participant in several important events in Texas and Oklahoma history. A trailhead is the point at which a trail begins , where the trail is often intended for hiking , biking , horseback riding , or off - road vehicles . Modern trailheads often contain rest rooms , maps , sign posts and distribution centers for informational brochures about the trail and its features , and parking areas for vehicles and trailers . Historically , the cities located at the terminus of major pathways for foot traffic such as the Natchez Trace and the Chisholm Trail were also known as trailheads . For mountain climbing and hiking , the elevation of the trailhead above sea level is given to give an idea of how high the mountain is above the average terrain .
candidates: activity amino acid ancient greek area biology border capital cell census city colonization county die dna field forest fur genetics government greek human idea junction life location march metropolitan area music name part pathways point population position process protein red research river seat second state station structure supreme court term third trade trade route trader trail tribe vessel war wind word
answer: location