query: instance_of tiger horse
supports: In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements. Mutations result from errors during DNA replication or other types of damage to DNA, which then may undergo error-prone repair (especially microhomology-mediated end joining), or cause an error during other forms of repair, or else may cause an error during replication (translesion synthesis). Mutations may also result from insertion or deletion of segments of DNA due to mobile genetic elements. Mutations may or may not produce discernible changes in the observable characteristics (phenotype) of an organism. Mutations play a part in both normal and abnormal biological processes including: evolution, cancer, and the development of the immune system, including junctional diversity. The Appaloosa (also known as Southwest to Sonora) is a 1966 American Western film Technicolor (set in the 1870s) from Universal Pictures starring Marlon Brando, Anjanette Comer and John Saxon, who was nominated for a Golden Globe for Best Supporting Actor for his portrayal of a Mexican bandit. The film was directed by Sidney J. Furie, and shot in Wrightwood, Antelope Valley, and Lake Los Angeles, California, St. George, Utah, and Colorado City, Arizona. Tiger horses are gaited , spotted horses with a coat color much like the Appaloosa . The tiger horse can exhibit various ambling gaits including various lateral gaits called the `` Glider Gait '' or Indian shuffle , stepping pace , and running walk , as well as the diagonal Fox Trot . Registered horses must exhibit gaits without artificial aids and while flat - shod . A gene is a locus (or region) of DNA which is made up of nucleotides and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as geneenvironment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life. The Appaloosa is an American horse breed best known for its colorful spotted coat pattern. There is a wide range of body types within the breed, stemming from the influence of multiple breeds of horses throughout its history. Each horse's color pattern is genetically the result of various spotting patterns overlaid on top of one of several recognized base coat colors. The color pattern of the Appaloosa is of interest to those who study equine coat color genetics, as it and several other physical characteristics are linked to the leopard complex mutation (LP). Appaloosas are prone to develop equine recurrent uveitis and congenital stationary night blindness; the latter has been linked to the leopard complex. The leopard complex is a group of genetically-related coat patterns in horses. These patterns range from progressive increases in interspersed white hair similar to graying or roan to distinctive, Dalmatian-like leopard spots on a white coat. Secondary characteristics associated with the leopard complex include a white sclera around the eye, striped hooves and mottled skin. The leopard complex genes are also linked to abnormalities in the eyes and vision. These patterns are most closely identified with the Appaloosa horse breed, though its presence in breeds from Asia to western Europe has indicated that it is due to a very ancient mutation. Equine recurrent (periodic) uveitis (moon blindness, recurrent iridocyclitis) is an acute, nongranulomatous inflammation of the uveal tract of the eye, occurring commonly in horses of all breeds, worldwide. The causative factor is not known, but several pathogeneses have been suggested. It is the most common cause of blindness in horses. In some breeds, a genetic factor may be involved. Equine coat color genetics determine a horse's coat color. There are many different coat colors possible, but all colors are produced by the action of only a few genes. The simplest genetic default color of all domesticated horses can be described as either "red" or "non-red", depending on whether a gene known as the "Extension" gene is present . When no other genes are active, a "red" horse is the color popularly known as a chestnut. Black coat color occurs when the Extension gene is present, but no other genes are acting on coat color.The "Agouti" gene can be recognized only in "non-red" horses; it determines whether black color is uniform, creating a black horse, or limited to the extremities of the body, creating a bay horse. A horse breed is a selectively bred population of domesticated horses, often with pedigrees recorded in a breed registry. However, the term is sometimes used in a very broad sense to define landrace animals, or naturally selected horses of a common phenotype located within a limited geographic region. Depending on definition, hundreds of "breeds" exist today, developed for many different uses. Horse breeds are loosely divided into three categories based on general temperament: spirited "hot bloods" with speed and endurance; "cold bloods," such as draft horses and some ponies, suitable for slow, heavy work; and "warmbloods," developed from crosses between hot bloods and cold bloods, often focusing on creating breeds for specific riding purposes, particularly in Europe. 
candidates: acting action bay biology breed city coat color damage definition environment film gene genetics globe group horse horse breed inflammation lake leopard organism part pattern population region result riding sense system three tract valley virus vision work
answer: horse breed