query: instance_of mdl chime
supports: Molecular graphics (MG) is the discipline and philosophy of studying molecules and their properties through graphical representation. IUPAC limits the definition to representations on a "graphical display device". Ever since Dalton's atoms and Kekulé's benzene, there has been a rich history of hand-drawn atoms and molecules, and these representations have had an important influence on modern molecular graphics. This article concentrates on the use of computers to create molecular graphics. Note, however, that many molecular graphics programs and systems have close coupling between the graphics and editing commands or calculations such as in molecular modelling. Symyx Technologies, Inc. was a company that specialized in informatics and automation products. Symyx provided software solutions for scientific research, including Enterprise Laboratory Notebooks and products for combinatorial chemistry. The software part of the business became part of Accelrys, Inc. in 2010. Symyx also offered laboratory robotics systems for performing automated chemical research, which on 2010, was spun out as Freeslate, Inc. MDL Chime is a free plugin used by web browsers to display the three - dimensional structures of molecules . It is part of the ISIS product line acquired by Symyx Technologies from scientific publisher Elsevier in October 2007 . It is based on the RasMol code . Chime is used by a wide range of biochemistry web sites for the visualization of macromolecules . Many of these sites are linked to the World Index of Molecular Visualization Resources MolVisIndex.Org . Chime was also used until 2006 at the Protein Data Bank to examine structures stored there . Although available in 1996 in both Windows 95 and Mac OS versions for both Netscape and Internet Explorer browsers , development of Chime did not follow the move to Mac OS X for the Mac and support for Windows - based browsers other than Internet Explorer was limited ( although it works well in Mozilla Firefox ) . One significant feature added in 1997 was the ability to display spectroscopic data in the form of the IUPAC JCAMP - DX protocols . Apart from this , most updates since then were for the installation package to follow the development of Windows and Internet Explorer . Chime largely has been superseded by Jmol . Jmol is a non-proprietary open source Java molecular visualization application / applet that has maintained most Chime command compatibility while adding features . A feature of Chime which is not yet reproduced with Jmol is the calculation of electrostatic or hydrophobic potential for use in coloring molecular surfaces . Instead , Jmol relies on this data being provided by other calculation packages . Chime involves some level of calculation of these properties . Now Chime is owned by Symyx and is found at Accelrys , and has been merged to Discovery Studio . Accelrys is a software company headquartered in the United States, with representation in Europe and Asia. It provides software for chemical, materials and bioscience research for the pharmaceutical, biotechnology, consumer packaged goods, aerospace, energy and chemical industries. Combinatorial chemistry comprises chemical synthetic methods that make it possible to prepare a large number (tens to thousands or even millions) of compounds in a single process. These compound libraries can be made as mixtures, sets of individual compounds or chemical structures generated by computer software. Combinatorial chemistry can be used for the synthesis of small molecules and for peptides. A molecule is an electrically neutral group of two or more atoms held together by chemical bonds. Molecules are distinguished from ions by their lack of electrical charge. However, in quantum physics, organic chemistry, and biochemistry, the term "molecule" is often used less strictly, also being applied to polyatomic ions. The Lancet is a weekly peer-reviewed general medical journal. It is one of the world's oldest and best known general medical journals. Elsevier is one of the world's major providers of scientific, technical, and medical information, and a technology company originally established in 1880. It is now a part of the RELX Group, known until 2015 as Reed Elsevier. Its products include journals such as "The Lancet" and "Cell", the ScienceDirect collection of electronic journals, the "Trends" and "Current Opinion" series of journals, and the online citation database Scopus. A web browser (commonly referred to as a browser) is a software application for retrieving, presenting and traversing information resources on the World Wide Web. An "information resource" is identified by a Uniform Resource Identifier (URI/URL) that may be a web page, image, video or other piece of content. Hyperlinks present in resources enable users easily to navigate their browsers to related resources. Scopus is a bibliographic database containing abstracts and citations for academic journal articles. It covers nearly 22,000 titles from over 5,000 publishers, of which 20,000 are peer-reviewed journals in the scientific, technical, medical, and social sciences (including arts and humanities). It is owned by Elsevier and is available online by subscription. Searches in Scopus also incorporate searches of patent databases. RasMol is a computer program written for molecular graphics visualization intended and used mainly to depict and explore biological macromolecule structures, such as those found in the Protein Data Bank. It was originally developed by Roger Sayle in the early 1990s. ScienceDirect is a website which provides subscription-based access to a large database of scientific and medical research. It hosts over 12 million pieces of content from 3,500 academic journals and 34,000 e-books. The journals are grouped into four main sections: "Physical Sciences and Engineering", "Life Sciences", "Health Sciences", and "Social Sciences and Humanities". Article abstracts are freely available, but access to their full texts (in PDF and, for newer publications, also HTML) generally require a subscription or pay-per-view purchase. The Protein Data Bank (PDB) is a crystallographic database for the three-dimensional structural data of large biological molecules, such as proteins and nucleic acids. The data, typically obtained by X-ray crystallography, NMR spectroscopy, or, increasingly, cryo-electron microscopy, and submitted by biologists and biochemists from around the world, are freely accessible on the Internet via the websites of its member organisations (PDBe, PDBj, and RCSB). The PDB is overseen by an organization called the Worldwide Protein Data Bank, wwPDB. RELX Group (known as Reed Elsevier between 1992 and February 2015) is a multinational information and analytics company based in London, in the United Kingdom. It operates in four market segments: scientific, technical and medical; risk and business analytics; legal; and exhibitions. 
candidates: academic journal article automation bank chemical company computer computer program crystallographic database data database definition editing electron february group health information journal market molecule note number part patent peer philosophy physics process protein series software technology technology company three two website
answer: software