query: instance_of pseudoangiomatous stromal hyperplasia
supports: The torso or trunk is an anatomical term for the central part of the many animal bodies (including that of the human) from which extend the neck and limbs. The torso includes the thorax and the abdomen. A mammary gland is an exocrine gland in mammals that produces milk to feed young offspring. Mammals get their name from the word "mammary". The mammary glands are arranged in organs such as the breasts in primates (for example, humans and chimpanzees), the udder in ruminants (for example, cows, goats, and deer), and the dugs of other animals (for example, dogs and cats). Lactorrhea, the occasional production of milk by the glands, can occur in any mammal, but in most mammals lactation, the production of enough milk for nursing, occurs only in phenotypic females who have gestated in recent months or years. It is directed by hormonal guidance from sex steroids. In a few mammalian species, male lactation can occur. Androgen (from Greek "andro" meaning male human being), also called androgenic hormone or testoid, is any natural or synthetic compound, usually a steroid hormone, that stimulates or controls the development and maintenance of male characteristics in vertebrates by binding to androgen receptors. This includes the activity of the primary male sex organs and development of male secondary sex characteristics. Androgens were first discovered in 1936. Androgens increase in both boys and girls during puberty. Androgens are also the original anabolic steroids and the precursor of all estrogens. The primary and most well-known androgen is testosterone. Dihydrotestosterone (DHT) and androstenedione are less known generally, but are of equal importance in male development. DHT in the embryo life causes differentiation of penis, scrotum and prostate. Later in life DHT contributes to balding, prostate growth and sebaceous gland activity. Although androgens are described as male sex hormones, both males and females have them to varying degrees, as is also true of estrogens. They are one of three types of sex hormones, the others being estrogens like estradiol and progestogens like progesterone. An infant (from the Latin word "infans", meaning "unable to speak" or "speechless") is the more formal or specialised synonym for "baby", the very young offspring of a human or other animal.  Pathology (from the Greek roots of "pathos", meaning "experience" or "suffering", and "-logia", "study of") is a significant component of the causal study of disease and a major field in modern medicine and diagnosis. Testosterone is the primary male sex hormone and an anabolic steroid. In men, testosterone plays a key role in the development of male reproductive tissues such as the testis and prostate, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of body hair. In addition, testosterone is essential for health and well-being, and for the prevention of osteoporosis. Insufficient levels of testosterone in men may lead to abnormalities including frailty and bone loss. Estrogen (American English) or oestrogen (British English) is the primary female sex hormone as well as a medication. It is responsible for the development and regulation of the female reproductive system and secondary sex characteristics. "Estrogen" may also refer to any substance, natural or synthetic, that mimics the effects of the natural hormone. The estrane steroid estradiol is the most potent and prevalent endogenous estrogen, although several metabolites of estradiol also have estrogenic hormonal activity. Estrogens are used as medications as part of some oral contraceptives, in hormone replacement therapy for postmenopausal, hypogonadal, and transgender women, and in the treatment of certain hormone-sensitive cancers like prostate cancer and breast cancer. They are one of three types of sex hormones, the others being androgens/anabolic steroids like testosterone and progestogens like progesterone. Medicine (British English ; American English ) is the science and practice of the diagnosis, treatment, and prevention of disease. The word "medicine" is derived from Latin "medicus", meaning "a physician". Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Growth hormone (GH), also known as somatotropin (or as human growth hormone [hGH or HGH] in its human form), is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals. It is thus important in human development. It is a type of mitogen which is specific only to certain kinds of cells. Growth hormone is a 191-amino acid, single-chain polypeptide that is synthesized, stored, and secreted by somatotropic cells within the lateral wings of the anterior pituitary gland. A disease is a particular abnormal condition, a disorder of a structure or function, that affects part or all of an organism. The study of disease is called pathology which includes the causal study of etiology. Disease is often construed as a medical condition associated with specific symptoms and signs. It may be caused by external factors such as pathogens, or it may be caused by internal dysfunctions particularly of the immune system such as an immunodeficiency, or a hypersensitivity including allergies and autoimmunity. A primate is a mammal of the order Primates (Latin: "prime, first rank"). In taxonomy, primates include two distinct lineages, strepsirrhines and haplorhines. Primates arose from ancestors that lived in the trees of tropical forests; many primate characteristics represent adaptations to life in this challenging three-dimensional environment. Most primate species remain at least partly arboreal. Puberty is the process of physical changes through which a child's body matures into an adult body capable of sexual reproduction. It is initiated by hormonal signals from the brain to the gonads: the ovaries in a girl, the testes in a boy. In response to the signals, the gonads produce hormones that stimulate libido and the growth, function, and transformation of the brain, bones, muscle, blood, skin, hair, breasts, and sex organs. Physical growthheight and weightaccelerates in the first half of puberty and is completed when an adult body has been developed. Until the maturation of their reproductive capabilities, the pre-pubertal physical differences between boys and girls are the external sex organs. Breast development, also known as mammogenesis, is a complex biological process in primates that takes place throughout a female's life. It occurs across several phases, including prenatal development, puberty, and pregnancy. At menopause, breast development ceases and the breasts atrophy. Breast development results in prominent and developed structures on the chest known as breasts in primates, which serve as both a sexual characteristic and as mammary glands. The process is mediated by an assortment of hormones (and growth factors), the most important of which include estrogen, progesterone, prolactin, and growth hormone. A hormone (from the Greek participle ) is any member of a class of signaling molecules produced by glands in multicellular organisms that are transported by the circulatory system to target distant organs to regulate physiology and behaviour. Hormones have diverse chemical structures, mainly of 3 classes: eicosanoids, steroids, and amino acid derivatives (amines, peptides, and proteins). The glands that secrete hormones comprise the endocrine signaling system. The term hormone is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signalling) or nearby cells (paracrine signalling). Diagnosis is the identification of the nature and cause of a certain phenomenon. Diagnosis is used in many different disciplines with variations in the use of logic, analytics, and experience to determine "cause and effect". In systems engineering and computer science, it is typically used to determine the causes of symptoms, mitigations, and solutions. The breast is one of two prominences located on the upper ventral region of the torso of female primates. In females, it serves as the mammary gland, which produces and secretes milk and feeds infants. Both females and males develop breasts from the same embryological tissues. At puberty, estrogens, in conjunction with growth hormone, cause breast development. Males do not develop pronounced or physiologically matured breasts because their bodies produce lower levels of estrogens and higher levels of androgens, namely testosterone, which suppress the effects of estrogens in developing breast tissue. The breasts of females are typically far more prominent than those of males. In breast pathology , pseudoangiomatous stromal hyperplasia , commonly abbreviated PASH , is an overgrowth of myofibroblastic cells and has an appearance similar to fibroadenomatoid changes . The diagnostic significance is currently uncertain , but it appears to be benign . There have been cases of PASH diagnosed where the tumors co-exist with breast cancer . Other cases have made screening for breast cancer difficult and in some cases impossible due to the number and density of the existing PASH tumors . These cases have resulted in the necessity of a mastectomy and double mastectomy .
candidates: acid activity adult bone boy brain cause cell chain chest child class complex component computer condition disease environment girl gland health hormone human humans medicine member muscle name offspring order penis process rank region reproduction research science sex single skin study synonym term three treatment two variety word
answer: disease