5-MeO-DET

5-MeO-DET or 5-methoxy-"N,N"-diethyltryptamine is a hallucinogenic tryptamine.
Pharmacology.
5-MeO-DET inhibits serotonin reuptake with an IC50 value of 2.4 μM and activates 5-HT2A receptors with an EC50 value of 8.11 nM.
Effects.
Low dosages (0.5–1 mg) are reported to produce a relaxing body high and mild entheogenic effects. Shulgin reports in TiHKAL that higher dosages (1–3 mg) can produce very unpleasant reactions.