Skin Horse

Skin Horse is a webcomic written by Shaenon K. Garrity and Jeffrey Channing Wells, and drawn by Garrity. The storylines center around the misadventures of the staff of a little-known government agency working on "Project Skin Horse". The strip started on December 31, 2007 and updates every day of the week (although the Sunday updates consist of fan art, sketches, and background). "Skin Horse" is part of Webcomics Nation, where it is free to read. It is also syndicated on GoComics, where the past month's updates are free to read, with further archives available to subscribers.
About.
"Project Skin Horse" is secret Federal government agency, a non-human advocacy bureau responsible for rescuing and resettling non-human sapient beings created by mad scientists. For example, in the "Cowardly Lion" story arc, a lion augmented with human intelligence is roaming loose in a zoo. Skin Horse field operatives subdue, transport, and resettle the lion in a sanctuary for sapient large cats. The rescued sapient beings are referred to as "clients". With the exception of the character Tip, the employees of the agency are themselves rescued former clients. An informal name for the organization is "Black Ops Social Services". They tend to cross paths with a rival black ops military research organization known "Anasigma".
Unlike Garrity's earlier comic, "Narbonic", mad scientists do not play a central role. Rather, their monstrous creations do. 
Although the strip was conceived by and is drawn by Garrity, she and Wells co-write, brainstorming ideas together, with some scripts written by Garrity and others by Wells.
The title is taken from a character name in the 1922 children's book "The Velveteen Rabbit", where one passage reads: "'Real isn't how you are made,' said the Skin Horse, 'It's a thing that happens to you ... Then you become Real.'"
Cast.
Tip.
Dr. Dennis "Tip" Wilkin, a relatively new field operative and the only fully human employee of Project Skin Horse, is a decorated former captain of the U.S. Army, a trained psychologist, a passionate cross-dresser and an almost supernatural seducer. Tip is essentially a research psychologist, but in an emergency he can wield therapy puppets.
Sweetheart.
Captain's Fancy Valentine Sweetheart is a genetically modified sapient dog, created by a mad scientist. She now works for Project Skin Horse as a field operative. She is generally the most clear-thinking and rational team member, but periodically exhibits feelings of insecurity.
Unity.
Unity is a "necrotic" being: dead tissue animated through a secret military process. A field operative for Project Skin Horse, she is Sweetheart's best friend. Unity was developed to be a bio-weapon, but proved to be too hard to control and was therefore moved to Project Skin Horse. Unity is good-natured, likes guns, and is inclined to use gratuitously unnecessary violence. Her safety phrase, "Blueberry waffles", to suspend her aggression patterns, was only revealed by Anasigma after Project Skin Horse had spent a fortune on obedience classes.
Unity as a creature is actually a nanotechnology ooze that controls the body it inhabits, as seen in the "Once and Future" story arc. As such, she can be transferred (with help) into another body or creature, although living bodies will reject her after a time, usually by vomiting her out. Her current body is an amalgam of various human corpses of varying ethnicities, and several times throughout the series, she has been seen to add, remove, or adapt to new body parts.
Unity is also seen to gain intelligence proportional to the amount of brains she consumes, although social graces are not included with this increase. During the story arc "Railway Children," she consumes a vast quantity of artificially produced brains, and with it gains superhuman intelligence levels. She repeats this during the events of "My brother Sam is Dead," only to use her insight to make comments about her teammates' behavior that leave them distrusting of her in this heightened state.
Gavotte.
The administrative leader of Project Skin Horse, Gavotte is a collective being consisting of a swarm of bees that thinks with a single female mind. Most of the other agency employees are nervous around her—Tip in particular since he is fatally allergic to bee stings.
Moustachio the Thinkonium.
A 19th century wind-up automaton of destruction with a clockwork brain, Moustachio is the receptionist at Project Skin Horse. He has a limited long-term memory and needs wax cylinders from cold storage to remember his earlier days. His legs were removed by the British government as a safety precaution. He thinks and speaks like a 19th-century gentleman and has little regard for or knowledge of new technology.
Nick Zerhakker.
A young adult, introduced in the "I Can Fly" story arc, video game obsessive Nick was unknowingly co-opted into "Project Whirligig". The black military program intended to weaponize him by secretly installing him in a virtual reality, then removing his brain and implanting it in a black V-22 Osprey–a military tiltrotor aircraft–and finally subconsciously training Nick to control the Osprey as if it were his own body. In spite of Nick's love of shooting virtual bad guys, he abhors the thought of killing real people, and so joined the Skin Horse team.
Reception.
"Io9" praised Garrity and Wells for "piling absurdities onto absurdities without overcrowding their stories".
"Comic Book Resources" (reviewing the first collected volume) called it "delightful" and "laugh-out-loud funny, in the way that the Marx Brothers were funny", and lauded it for "deliver(ing) a gag every day and also build(ing) up a larger storyline", comparing the "easygoing" and "simple, cartoony" art to Walt Kelly, but faulted Garrity's "tendency to crowd the panels with text: "the dialogue really sparkles, but it also takes up a lot of space on the page."