According to Lange Gynecology and obstetrics, 8th edition, a persistent break through bleeding and amenorrhea commonly reflect an atrophic endometrium, which means a thin and not developed endometrium.
According to Lange Gynecology and obstetrics, 8th edition, the most common side effect associated with OC use is breakthrough bleeding. Persistent break through bleeding and amenorrhea commonly reflect an atrophic endometrium, which means a thin and not developed endometrium.