Consider acetic acid and its mono -, di -, and trifluoroacetic derivatives and their pK a values (4.74,2.66,1.24, and 0.23); in other words, the trifluoro derative is 33,800 times stronger an acid than acetic.
Consider acetic acid and its mono -, di -, and trifluoroacetic derivatives and their pK a values (4.74,2.66,1.24, and 0.23). Because of this, the trifluoro derative is 33,800 times stronger an acid than acetic.