The action of azimilide is directed on to the different currents present in most parts of the heart, it will block I Kr, I Ks, I Na, I Ca, I NCX and I K.Ach.
The action of azimilide is directed to the different currents present in atrial and ventricular cardiac myocytes. It principally blocks I Kr, and I Ks, with much weaker effects on I Na, I Ca, I NCX and I K.Ach.