The squadron was activated for a third time on 1 March 1960 as the 37th Air Defense Missile Squadron and stood alert during the Cold War, with IM-99A (later CIM-10) BOMARC surface to air antiaircraft missiles.
The squadron was activated for a third time on 1 March 1960 as the 37th Air Defense Missile Squadron It initially monitored the construction of the BOMARC missile facility near Raco, Michigan. By the end of 1961 the squadron stood alert using its complement of 24 IM-99B (later CIM-10) BOMARC surface to air antiaircraft missiles.