Chlorofluorocarbons were used almost universally as refrigerants and propellants due to their relatively low toxicity and high heat of vaporization, however, they have been phased out, due to their contribution to ozone depletion, and have largely been replaced by HFCs.
Chlorofluorocarbons were used almost universally as refrigerants and propellants due to their relatively low toxicity and high heat of vaporization. Starting in the 1980's, as their contribution to ozone depletion became known, their use was increasingly restricted, and they have now largely been replaced by HFCs.