The disease progressively spreads from the initial location, resulting in atrophy of the skin and its adnexa, as well as underlying subcutaneous structures such as connective tissue, (fat, fascia, cartilage, bones) and/or muscles of one side of the face.
The disease progressively spreads from the initial location, resulting in atrophy of the underlying subcutaneous structures, including fat, cartilage, muscle, and sometimes even bone. All affected individuals develop progressive atrophy of the skin and its adnexa, as well as the subcutaneous connective tissue, (fat, fascia, cartilage, bones) and/or muscles of one side of the face.