The most widely-known and application of migratory insertion of carbonyl groups is the Monsanto acetic acid process, which uses an rhodium-iodine catalyst system to transform methanol into acetic acid under relatively mild, catalytic conditions.
The most widely-known and widely-used application of migratory insertion of carbonyl groups is the Monsanto acetic acid process. This reaction, through an iodine intermediate, transforms methanol into acetic acid under relatively mild, catalytic conditions.