Syedna Mohammed Burhanuddin was born in the era of 46th Da'i al-Mutlaq Syedna Mohammed Badruddin, he served his father the 47th Da'i al-Mutlaq Syedna Abdul Qadir Najmuddin and also served his uncle the 48th Da'i al-Mutlaq Syedna Abdul Husain Husamuddin.
Syedna Mohammed Burhanuddin was born in the same year when his father became 47th Da'i al-Mutlaq of the Dawoodi Bohra sect. He served his father the Syedna Abdul Qadir Najmuddin and also served his uncle the 48th Da'i al-Mutlaq Syedna Abdul Husain Husamuddin.