The costamere is a structural-functional component of striated muscle cells which, according to original descriptions in the early 1980s (which are generally still accepted), are sub-sarcolemmal protein assemblies circumferentially aligned in register with the Z-disk of peripheral myofibrils.
The costamere is a structural-functional component of striated muscle cells which connects the sarcomere of the muscle to the cell membrane. Costameres are sub-sarcolemmal protein assemblies circumferentially aligned in register with the Z-disk of peripheral myofibrils.