Some dissociative drugs including ketamine, PCP, and DXM are known to cause clinical psychological dependence, chemical dependence, and NMDA receptor antagonist neurotoxicity (NAN), when used chronically.
Some dissociative drugs including ketamine, PCP, and DXM are one of the few drugs that are known known to cause clinical psychological dependence. They also induce chemical dependence, and NMDA receptor antagonist neurotoxicity (NAN), when used chronically.