Oxidative stress can directly cause neuron cell death or it can trigger a cascade of events that leads to protein misfolding, proteasomal malfunction, mitochondrial dysfunction, or glial cell activation.
Oxidative stress can directly cause neurodegradation through apoptosis or it can trigger a cascade of events, which eventually lead to neurodegradation. These events include protein misfolding, proteasomal malfunction, mitochondrial dysfunction, and glial cell activation.