In March 2016, it was confirmed that Sarah Wayne Callies will reprise her role as Dr. Sara Tancredi, and that filming will begin in April 2016 in Vancouver.
In March 2016, it was confirmed that Sarah Wayne Callies and Amaury Nolasco would reprise their role as Dr. Sara Tancredi and Fernando Sucre, respectively. Filming will begin in April 2016 in Vancouver.