Vaksin COVID-19 Moderna atawa  mRNA-1273 adalah sabuah vaksin COVID-19 nang dikambangakan ulih National Institute of Allergy and Infectious Diseases (NIAID), Biomedical Advanced Research and Development Authority (BARDA), dan Moderna. Paksin ngitu dipakaiakan malalui suntikan intraotot. Wayah 18 Disimbir 2020, mRNA-1273 dikaluarakan malalui papadah pamakaian kapalipitan ulih Food and Drug Administration (FDA) Amerika Serikat.