Prempeh College yɛ  aban ntoasoɔ sukuu ma mmarima a ɛwɔ Asantemantem ahenkro Kumasi wɔ ɔman Ghana mu. Asanteman mpaninfoɔ, Enyirisi Aban, Methodist Asɔre ne Presby asɔre na ɛkaa wɔn ho bɔɔmu tee sukuu yi wɔ afe 1949. Wɔde sukuu no too Asantehene, Otumfoɔ Sir Osei Tutu Agyeman Prempeh II, a ɔmaa asaase a wɔde sii sukuu no. Wɔde Eton College a ɛwɔ Enyirisiman mu na  ɛyɛɛ nhwɛsoɔ. Sukuu yi diikan wɔ nnipa dodoɔ a wɔgyee wɔn wɔ Kwame Nkrumah Suapɔn mu (Kwame Nkrumah University of Science and Technology) wɔ afe 2004 mu  wɔ abrɛ a wɔgyee asukuufoɔ 441 na afe 2012 nso, wɔgyee asukuufoɔ 296 firii Prempeh College. Dodoɔ noaa gye tum sɛ sukuu no yɛ ntosoɔ sukuu a edimu wɔ ɔman Ghana mu. Sukuu no adi nkunim mprensa wɔ ɔman mu akansie a wato din sɛ "National Robotics Championships" ɛ  re afe 2013 kɔsi afe 2016. Wɔ afe 2016 mu no, Prempeh College nyaa abasobɔdeɛ keseɛ a wato din sɛ "Toyota Innovation Award" wɔ amanman akansie a wato din sɛ International Robofest World Championships wɔ Michigan, Amerika man mu.