VNUS MEDICAL TECHNOLOGIES INC
EXHIBIT 10.1
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<DESCRIPTION>EXHIBIT 10.1
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<DIV align="right" style="font-size: 10pt; margin-top: 12pt"><B>Exhibit&nbsp;10.1</B>
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<DIV align="left" style="font-size: 10pt; margin-top: 12pt">January&nbsp;15, 2008
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<DIV align="left" style="font-size: 10pt; margin-top: 6pt">Mr.&nbsp;Peter Osborne<BR>
1737 Fabian Drive<BR>
San Jose, CA 95124

</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">Dear Peter:

</DIV>
<DIV align="left" style="font-size: 10pt; margin-top: 6pt">On behalf of VNUS Medical Technologies, Inc. (&#147;VNUS&#148; or the &#147;company&#148;), I am pleased to offer you
the position of Chief Financial Officer and Vice President of Finance &#038; Administration, reporting
to the President and CEO. In making this offer we are expressing our enthusiastic support of your
abilities to help VNUS become a great success. You bring a skill set to this company that is
essential to achieving our goals, both short and long term. The purpose of this letter is to offer
you a position and detail the terms of your employment.
</DIV>

<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
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<TR valign="bottom">
    <TD width="12%">&nbsp;</TD>
    <TD width="3%">&nbsp;</TD>
    <TD width="85%">&nbsp;</TD>
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<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px"><B>Job Title:</B>
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">CFO &#038; Vice President of Finance and Administration</TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px"><B>Starting Date:</B>
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Friday, January&nbsp;18, 2008, or an earlier mutually agreed date.</TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px"><B>Salary:</B>
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">$280,000, payable in accordance with the company&#146;s standard payroll policies (currently bi-monthly). Your
initial performance review will be performed with an effective date of January&nbsp;1, 2009. You are also eligible
to participate in the company&#146;s 2008 officer bonus plan for a target bonus of approximately 35&nbsp;percent of annual
salary, pro-rated to your date of hire.</TD>
</TR>
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    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px"><B>Stock:</B>
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Subject to Board approval, you will be granted 20,000 restricted stock units at $0.00 per share as soon as
practicable during the open trading window following your first day of employment. These RSUs will vest 25%
each year. The first vesting will occur on the first anniversary of your date of hire, for a total vesting period
of 4&nbsp;years, so long as you are an employee of the company.</TD>
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    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Subject to Board approval, you will be granted 60,000 Stock Options as
soon as practicable during the open trading window following your first
day of employment. These options will be exercisable at the fair market
value of the shares on the date of the grant, and will vest 25&nbsp;percent
(15,000 shares) 12&nbsp;months from your date of hire, and 1/36th (1250 shares)
of the remaining balance for each month thereafter for an additional 36
months, for a total vesting period of 4&nbsp;years. These options may be
exercised up to 10&nbsp;years from the date of grant so long as you are an
employee of the company.</TD>
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<DIV style="font-family: 'Times New Roman',Times,serif">

<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
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    <TD width="12%">&nbsp;</TD>
    <TD width="3%">&nbsp;</TD>
    <TD width="85%">&nbsp;</TD>
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    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Subject to Board approval, you will be granted a contingent performance
award totaling not less than 10,000 RSUs vesting annually at 25&nbsp;percent
over four years. The criteria for achievement of the contingent award
will be determined by the Compensation Committee.</TD>
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    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
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<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px"><B>Benefits:</B>
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">The company will provide to you, medical, dental and vision coverage beginning the first
of the month after your start date. For an additional monthly charge, coverage for your
spouse and children may also be added. You are eligible to participate in the company&#146;s 401(k)
plan beginning the first of the month after your start date. The company has a discretionary
match of one-half of the first six percent of base salary deferred into the VNUS 401(k) plan,
capped at $2500.</TD>
</TR>
<TR>
<td>&nbsp;</td>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Life insurance coverage equal to twice your annual salary is provided to
you as part of the employee benefits program. Long-term disability
insurance is also provided after one month of employment. To help
employees pay for healthcare and dependent care expenses, the company has
adopted a flexible spending/reimbursement accounts program. This allows
you to pay for out-of-pocket medical, dental, and vision costs, as well as
dependent care expenses, with pre-tax wages</TD>
</TR>
<TR valign="bottom"><!-- Blank Space -->
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px"><B>Paid Time Off:</B>
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">You are eligible to accrue 18&nbsp;days of Paid Time Off during your first year of
employment. Two days of PTO accrual are added for each year of service up to a maximum of 28
days per year. You may accumulate up to 40&nbsp;days of banked PTO-time. In addition, in 2008, the
company will be closed for 13 holidays including the days from December&nbsp;24 to December&nbsp;31.</TD>
</TR>
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</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">This offer is contingent upon your executing VNUS&#146; <U>Proprietary Information and Inventions
Agreement</U> for new employees, signing the Arbitration Agreement, and providing the company with the legally required proof of your identity and authorization to work in
the United States within 72 hours of your first day of employment. VNUS is an at-will employer.
Employment-at-will may be terminated with or without cause, and with or without notice at any time,
by the employee or the company.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">This offer will remain in effect through January&nbsp;16, 2008. If you do accept, and I sincerely hope
you will, please fax an endorsed letter to HR&#146;s confidential fax at 408-365-8489, and return an
original signed copy by mail shortly thereafter.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">Peter, we believe you will be an outstanding addition to the company. We have an exciting
opportunity ahead of us to which you can make a significant contribution. We look forward to
working with you in a productive and mutually beneficial relationship.
</DIV>

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<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
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    <TD valign="top">Sincerely,</TD>
    <TD>&nbsp;</TD>
    <TD colspan="3" valign="top" align="left">Foregoing terms and conditions hereby accepted:</TD>
</TR>
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    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">/s/ Brian E. Farley
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">/s/ Peter Osborne</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
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    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR style="font-size: 1px">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top" style="border-top: 1px solid #000000">&nbsp;
</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top" style="border-top: 1px solid #000000">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Brian E. Farley
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top"><B>Peter Osborne</B>
</TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top"><B>Date</B></TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">President and</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Chief Executive Officer</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
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