XENOMETRIX INC \DE\
AMENDMENT TO SENIOR LINE OF CREDIT

<html>
<head>
<meta http-equiv="Content-type" content="text/html;charset=UTF-8">
<title>Directory List of /Archives/edgar/data/1000370</title>
<link rel="stylesheet" type="text/css" href="/css/third-party/reset.min.css">
<link rel="stylesheet" type="text/css" href="/css/third-party/960.min.css">
<link rel="stylesheet" type="text/css" href="/css/basic-1.css">
<!-- [if IE 7] -->
<style type="text/css">
#global-search-form input#global-search-button {
  padding:0 2px;
}
</style>
<style type="text/css">
/* headings and page sections */
h1 {
   border-bottom:1px solid #ccc;
}
.section {
   margin-bottom:24px;
}
.section h2 {
   border-bottom:1px solid #ccc;
   margin-bottom:12px;
}
/* chairman's quote */
blockquote {
   background-color:#003768;
   background-image:url(/images/chairman-quote-bg.jpg);
   background-position:left -38px;
   color:#fff;
   font-family:Georgia, serif;
   font-size:14px;
   height:178px;
   letter-spacing:1px;
   padding:12px 20px 12px 220px;
}
#quote {
   margin-bottom:6px;
}
#attribution {
   font-style:italic;
   margin-top:6px;
   text-align:right;
}
/* committee members list */
dl.members-list {
   float:left;
   margin:0;
   padding:0;
   list-style:none;
   margin:0 5px;
   width:260px;
}
dl.members-list dt {
   font-weight:bold;
   margin-top:9px;
}
dl.members-list dt:first-child {
   margin-top:0;
}
dl.members-list dd {
   font-size:10px;
}
/* committee news and meetings */
#news-list,
#meetings-list {
   margin:0;
   padding:0;
   list-style:none;
}
#meetings-list {
   margin-left:10px;
   margin-right:10px;
   padding:0;
   list-style:none;
}
#meetings-list li {
   font-weight:bold;
}
#meetings-list li ul {
   list-style-image:url(/images/square-bullet-dddddd-5x5.gif);
   margin-top:3px;
}
#meetings-list li li {
   font-weight:normal;
}
.img_icon { vertical-align: middle; padding-right: 5px; width: 20px; border: 0px; }
</style>
<script type="text/javascript" src="/js/third-party/jquery-1.7.1.min.js"></script>
<script type="text/javascript">
// adding the following class via JS allows for the creation of JS-specific style rules
48'html').addClass('js');
</script>
<script type="text/javascript" src="/js/third-party/jquery.hoverintent.min.js"></script>
<script type="text/javascript" src="/js/third-party/superfish.min.js"></script>
<script type="text/javascript" src="/js/basic.js">
<script type="text/javascript">
var _gaq = _gaq || [];
_gaq.push(['_setAccount', 'UA-30394047-1']);
_gaq.push(['_setDomainName', 'sec.gov']);
_gaq.push(['_trackPageview']);
_gaq.push(['_setSampleRate', '50']);
(function() {
    var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true;
    ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js';
    var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s);
})();
</script>
</head>
<body bgcolor="#FFFFFF" link="#807331" vlink="#FF0000">
<!-- SEC Web Analytics - For information please visit: http://www.sec.gov/privacy.htm#collectedinfo -->
<noscript><iframe src="//www.googletagmanager.com/ns.html?id=GTM-TD3BKV"
height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript>
<script>(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':
new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],
j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src=
'//www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);
})(window,document,'script','dataLayer','GTM-TD3BKV');</script>
<!-- End SEC Web Analytics -->
<div id="global-wrapper-bg-1" class="clearfix">
<div id="global-wrapper-bg-2">
<div id="global-wrapper-bg-3">
<div id="global-wrapper" class="container_12">
<div id="global-header" class="grid_12">
<img id="banner-seal" src="/images/global-banner-seal.png" width="110" height="110" alt="U.S. Securities and Exchange Commission" usemap="#banner-seal-map">
<map name="banner-seal-map">
<area shape="circle" coords="55,55,55" href="/index.htm" alt="U.S. Securities and Exchange Commission">
</map>
<a href="/index.htm"><img id="banner-org-name" src="/images/global-banner-org-name.png" width="225" height="60" alt="U.S. Securities and Exchange Commission"></a>
<div id="global-search">
<a href="/search/search.htm">Search Options</a>
</div>
<a id="global-skip-nav" href="#main-content">Skip to Main Content</a>
<div id="global-nav">
<ul class="clearfix">
<li>
<a href="/about.shtml">About</a>
<ul>
<li><a href="/about/whatwedo.shtml">What We Do</a></li>
<li><a href="/about/commissioner.shtml">Commissioners</a></li>
<li><a href="/about/laws.shtml">Securities Laws</a></li>
<li><a href="/about/secreports.shtml">Reports</a></li>
<li><a href="/jobs.shtml">Careers</a></li>
<li><a href="/contact.shtml">Contact</a></li>
</ul>
</li>
<li>
<a href="/divisions.shtml">Divisions</a>
<ul>
<li><a href="/divisions/corpfin.shtml">Corporation Finance</a></li>
<li><a href="/divisions/enforce.shtml">Enforcement</a></li>
<li><a href="/divisions/investment.shtml">Investment Management</a></li>
<li><a href="/divisions/riskfin.shtml">Risk, Strategy and Innovation</a></li>
<li><a href="/divisions/marketreg.shtml">Trading and Markets</a></li>
<li><a href="/about/offices/ocie.shtml">National Exam Program</a></li>
<li><a href="/divisions.shtml">All Divisions and Offices</a></li>
</ul>
</li>
<li>
<a href="/litigation.shtml">Enforcement</a>
<ul>
<li><a href="/litigation/litreleases.shtml">Litigation Releases</a></li>
<li><a href="/litigation/admin.shtml">Administrative Proceedings</a></li>
<li><a href="/litigation/opinions.shtml">Opinions and Adjudicatory Orders</a></li>
<li><a href="/divisions/enforce/friactions.shtml">Accounting and Auditing</a></li>
<li><a href="/litigation/suspensions.shtml">Trading Suspensions</a></li>
<li><a href="/news/newsroom/howinvestigationswork.html">How Investigations Work</a></li>
<li><a href="/alj.shtml">Administrative Law Judges</a></li>
</ul>
</li>
<li>
<a href="/rules.shtml">Regulation</a>
<ul>
<li><a href="/rules/proposed.shtml">Proposed Rules</a></li>
<li><a href="/rules/final.shtml">Final Rules</a></li>
<li><a href="/rules/interim-final-temp.shtml">Interim Final Temporary Rules</a></li>
<li><a href="/rules/other.shtml">Other Orders and Notices</a></li>
<li><a href="/rules/sro.shtml">Self-Regulatory Organizations</a></li>
<li><a href="/interps.shtml">Staff Interpretations</a></li>
</ul>
</li>
<li>
<a href="/investor.shtml">Education</a>
<ul>
<li><a href="http://investor.gov/">Investor.gov</a></li>
<li><a href="/investor/brokers.htm">Check Out a Broker or Adviser</a></li>
<li><a href="/investor/alerts.shtml">Investor Alerts and Bulletins</a></li>
<li><a href="/answers.shtml">Fast Answers</a></li>
<li><a href="/complaint/select.shtml">File a Tip or Complaint</a></li>
<li><a href="/investor/pubs.shtml">Publications</a></li>
</ul>
</li>
<li>
<a href="/edgar.shtml">Filings</a>
<ul>
<li><a href="/edgar/quickedgar.htm">Quick EDGAR Tutorial</a></li>
<li><a href="/edgar/searchedgar/companysearch.html">Company Filings Search</a></li>
<li><a href="/about/forms/secforms.htm">Descriptions of SEC Forms</a></li>
<li><a href="/answers/publicdocs.htm">Requesting Public Documents</a></li>
</ul>
</li>
<li>
<a href="/news/newsroom/index.html">News</a>
<ul>
<li><a href="/news/press.shtml">Press Releases</a></li>
<li><a href="/news/whatsnew/wn-today.shtml">What's New</a></li>
<li><a href="/about/upcoming-events.htm">Upcoming Events</a></li>
<li><a href="/news/digest.shtml">News Digest</a></li>
<li><a href="/news/webcasts.shtml">Webcasts</a></li>
<li><a href="/news/studies.shtml">Special Studies</a></li>
<li><a href="/news/speech.shtml">Speeches and Public Statements</a></li>
<li><a href="/news/testimony.shtml">Testimony</a></li>
</ul>
</li>
</ul>
</div>
</div>
<h1>Directory Listing /Archives/edgar/data/1000370</h1><div id="main-content" class="grid_10 push_2"><table summary="Directory Listing for /Archives/edgar/data/1000370"><tr><th>Name</th><th>Size</th><th>Last Modified</th><tr><td><a href="/Archives/edgar/data/1000370/000109581101501976"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000109581101501976</a></td><td></td><td>2001-05-10 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000105050201000358"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000105050201000358</a></td><td></td><td>2001-04-13 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000105050201000337"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000105050201000337</a></td><td></td><td>2001-04-09 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000105050201000276"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000105050201000276</a></td><td></td><td>2001-03-22 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000110935501000024"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000110935501000024</a></td><td></td><td>2001-03-02 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000105050201000137"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000105050201000137</a></td><td></td><td>2001-02-14 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000100547701000972"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000100547701000972</a></td><td></td><td>2001-02-14 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000105050200001274"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000105050200001274</a></td><td></td><td>2000-11-14 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000100009600000643"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000100009600000643</a></td><td></td><td>2000-09-28 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000100009600000337"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000100009600000337</a></td><td></td><td>2000-05-08 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000100547700003040"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000100547700003040</a></td><td></td><td>2000-04-11 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000105050200000128"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000105050200000128</a></td><td></td><td>2000-02-14 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000105050299000866"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000105050299000866</a></td><td></td><td>1999-11-15 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000100009699000573"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000100009699000573</a></td><td></td><td>1999-10-27 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000105050299000737"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000105050299000737</a></td><td></td><td>1999-10-04 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000100009699000520"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000100009699000520</a></td><td></td><td>1999-09-28 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000105050299000393"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000105050299000393</a></td><td></td><td>1999-07-12 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000105050299000375"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000105050299000375</a></td><td></td><td>1999-07-06 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000095013499004368"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000095013499004368</a></td><td></td><td>1999-05-17 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000104638199000013"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000104638199000013</a></td><td></td><td>1999-02-24 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000107304799000005"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000107304799000005</a></td><td></td><td>1999-02-22 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000107304799000003"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000107304799000003</a></td><td></td><td>1999-02-16 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000104638199000011"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000104638199000011</a></td><td></td><td>1999-02-16 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000095013499001131"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000095013499001131</a></td><td></td><td>1999-02-16 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000103570499000081"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000103570499000081</a></td><td></td><td>1999-02-10 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000095012998004796"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000095012998004796</a></td><td></td><td>1998-11-18 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000103570498000696"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000103570498000696</a></td><td></td><td>1998-11-13 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000103570498000601"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000103570498000601</a></td><td></td><td>1998-09-28 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000095013498005029"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000095013498005029</a></td><td></td><td>1998-06-04 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000095013498004472"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000095013498004472</a></td><td></td><td>1998-05-15 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000095013498003147"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000095013498003147</a></td><td></td><td>1998-04-10 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000095013498001304"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000095013498001304</a></td><td></td><td>1998-02-17 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000103570498000090"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000103570498000090</a></td><td></td><td>1998-02-12 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000091205798000575"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000091205798000575</a></td><td></td><td>1998-02-12 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000092242398000080"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000092242398000080</a></td><td></td><td>1998-01-29 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000103570498000037"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000103570498000037</a></td><td></td><td>1998-01-26 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000095013497009357"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000095013497009357</a></td><td></td><td>1997-12-16 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000092242397000941"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000092242397000941</a></td><td></td><td>1997-11-10 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000092242397000925"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000092242397000925</a></td><td></td><td>1997-11-10 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000103570497000331"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000103570497000331</a></td><td></td><td>1997-11-03 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000103570497000284"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000103570497000284</a></td><td></td><td>1997-10-17 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000095013497007034"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000095013497007034</a></td><td></td><td>1997-09-26 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000095013497004451"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000095013497004451</a></td><td></td><td>1997-06-05 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000095013497004004"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000095013497004004</a></td><td></td><td>1997-05-15 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000086404797000147"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000086404797000147</a></td><td></td><td>1997-04-10 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000095013497001117"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000095013497001117</a></td><td></td><td>1997-02-14 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000095013496006016"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000095013496006016</a></td><td></td><td>1996-11-12 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000095013496005528"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000095013496005528</a></td><td></td><td>1996-10-21 00:00:00</td></tr><tr><td><a href="/Archives/edgar/data/1000370/000095012996002299"><img class="img_icon" src="/icons/folder.gif" alt="folder icon">000095012996002299</a></td><td></td><td>1996-09-27 00:00:00</td></tr></table></div><div id="local-footer" class="grid_12">
</div><div id="page-variables" class="clearfix">
</div>
<div id="global-footer" class="grid_12">
<ul class="clearfix"><li><a href="/sitemap.shtml">Site Map</a></li><li><a href="/eeoinfo/sec_access.htm">Accessibility</a></li><li><a href="/about/offices/oacq.htm">Contracts</a></li><li><a href="/privacy.htm">Privacy</a></li><li><a href="http://www.sec-oig.gov/">Inspector General</a></li><li><a href="/jobs.shtml">Careers</a></li><li><a href="/contact.shtml">Contact</a></li></ul><ul class="clearfix"><li><a href="/foia.shtml">FOIA</a></li><li><a href="/eeoinfo.shtml">No FEAR Act &amp; EEO Data</a></li><li><a href="/open">Open Government</a></li><li><a href="/plainwriting.shtml">Plain Writing</a></li><li><a href="/links.shtml">Links</a></li><li><a href="http://investor.gov/">Investor.gov</a></li><li><a href="http://www.usa.gov/">USA.gov</a></li></ul>
</div>
</div> <!-- END LAYOUT WRAPPER -->
</div> <!-- END BACKGROUND WRAPPER 3 -->
</div> <!-- END BACKGROUND WRAPPER 2 -->
</div> <!-- END BACKGROUND WRAPPER 1 -->
</body></html>
