PHARMION CORP
LICENSE AGREEMENT
<DOCUMENT>
<TYPE>EX-10.38
<SEQUENCE>5
<FILENAME>d44563exv10w38.htm
<DESCRIPTION>LICENSE AGREEMENT
<TEXT>
<HTML>
<HEAD>
<TITLE>exv10w38</TITLE>
</HEAD>
<BODY bgcolor="#FFFFFF">
<!-- PAGEBREAK -->
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>
<DIV style="font-family: Helvetica,Arial,sans-serif">


<DIV align="right" style="font-size: 10pt; margin-top: 12pt">EXHIBIT 10.38
</DIV>

<DIV align="right" style="font-size: 10pt; margin-top: 12pt">CERTAIN
CONFIDENTIAL INFORMATION CONTAINED IN<BR>
THIS DOCUMENT, MARKED BY BRACKETS, HAS BEEN<BR>
OMITTED AND FILED SEPARATELY WITH THE<BR>
SECURITIES AND EXCHANGE COMMISSION PURSUANT TO<BR>
RULE 24B-2 OF THE SECURITIES EXCHANGE<BR>
ACT OF 1934, AS AMENDED
</DIV>



<DIV align="center" style="font-size: 10pt; margin-top: 18pt"><B>License Agreement</B>
</DIV>


<DIV align="Center" style="font-size: 10pt; margin-top: 6pt">on

</DIV>

<DIV align="Center" style="font-size: 10pt; margin-top: 6pt"><B>Amrubicin Hydrochloride (SM-5887)</B>

</DIV>

<DIV align="Center" style="font-size: 10pt; margin-top: 6pt">by and between

</DIV>

<DIV align="Center" style="font-size: 10pt; margin-top: 6pt"><B>Sumitomo Pharmaceuticals Co., Ltd.</B>

</DIV>

<DIV align="Center" style="font-size: 10pt; margin-top: 6pt">and

</DIV>

<DIV align="Center" style="font-size: 10pt; margin-top: 6pt"><B>Conforma Therapeutics Corporation</B>

</DIV>

<DIV align="Center" style="font-size: 10pt; margin-top: 6pt">Executed on June&nbsp;23, 2005

</DIV>

<P align="center" style="font-size: 10pt"><!-- Folio -->&nbsp;<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>



<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">TABLE OF CONTENTS
</DIV>

<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
<!-- Begin Table Head -->
<TR valign="bottom">
    <TD width="88%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="3%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="3%">&nbsp;</TD>
</TR>
<!-- End Table Head -->
<!-- Begin Table Body -->
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">RECITALS</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">1</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">1. DEFINITIONS</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">1</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">2. GRANT OF RIGHTS</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">6</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">2.1. Exclusive Right</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">6</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">2.2. Sublicense</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">6</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">2.3. License Grant Back to SUMITOMO</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">6</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">3. CONSIDERATION</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">6</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">3.1. Up-front and Milestone Payments</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">6</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">3.2. Bonus Payments</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">7</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">3.3. Sublicensee Payments</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">7</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">3.4. Non-Refundability</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">7</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">4. DEVELOPMENT</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">7</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">4.1. Technology Transfer</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">7</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">4.2. Implementation of Development</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">8</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:60px; text-indent:-15px">4.2.1. Implementation of Development</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">8</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:60px; text-indent:-15px">4.2.2. Joint Steering Committee</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">8</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:60px; text-indent:-15px">4.2.3. Development Plan</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">9</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">4.3. Clinical Supplies for Development</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">10</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:60px; text-indent:-15px">4.3.1. Supply of Product</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">10</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:60px; text-indent:-15px">4.3.2. Specifications</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">10</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:60px; text-indent:-15px">4.3.3. Labeling and Packaging</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">11</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">5. MARKETING AND PROMOTION</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">11</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">5.1. Commercially Reasonable Efforts to Market</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">11</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">5.2. Commercialization Plan</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">11</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">5.3. Minimum Sales</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">12</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">5.4. Sales Outside the Territory</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">12</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">5.5. Labels and Packages</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">12</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">5.6. Competing Product</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">13</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">6. SUPPLY OF PRODUCT</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">13</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">6.1. Supply of Product</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">13</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:60px; text-indent:-15px">6.1.1. Supply Agreement</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">13</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:60px; text-indent:-15px">6.1.2. Requirements</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">13</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:60px; text-indent:-15px">6.1.3. Specifications</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">14</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:60px; text-indent:-15px">6.1.4. Delivery</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">14</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">6.2. Payment</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">14</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:60px; text-indent:-15px">6.2.1. Purchase Price during the Initial Period</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">14</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:60px; text-indent:-15px">6.2.2. Payments Procedure</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">14</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:60px; text-indent:-15px">6.2.3. Adjustments to Purchase Price After the Initial Period</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">15</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:60px; text-indent:-15px">6.2.4. Adjustment related to Combination Product</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">16</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">6.3. Forecast and Order</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">16</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:60px; text-indent:-15px">6.3.1. Supply Forecast</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">16</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:60px; text-indent:-15px">6.3.2. Firm Order</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">17</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:60px; text-indent:-15px">6.3.3. Quantity</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">17</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:60px; text-indent:-15px">6.3.4. Quality Assurance Tests</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">17</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:60px; text-indent:-15px">6.3.5. Retention of Samples</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">17</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:60px; text-indent:-15px">6.3.6. Labeling and Packaging</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">18</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:60px; text-indent:-15px">6.3.7. Backup/Complementary Source for the Manufacture of Compound or Product</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">18</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">6.4. Termination</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">18</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">7. TRADEMARK</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">18</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">7.1. Grant of Right</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">18</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">7.2. Ownership</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">18</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">7.3. Filing, Prosecution and Maintenance</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">18</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">7.4. Royalties for Trademark</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">19</TD>
    <TD>&nbsp;</TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>


<P align="center" style="font-size: 10pt"><!-- Folio -->&nbsp;<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
<!-- Begin Table Head -->
<TR valign="bottom">
    <TD width="88%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="3%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="3%">&nbsp;</TD>
</TR>
<!-- End Table Head -->
<!-- Begin Table Body -->
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">7.5. Infringement by Third Party</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">19</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:30px; text-indent:-15px">8. REGULATORY AFFAIRS AND INSPECTIONS</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">20</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">8.1. Acquisition and Maintenance of Authorization</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">20</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">8.2. Maintenance of Data</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">20</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">8.3. Inspections by Regulatory Authority</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">21</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">8.4. Inspections by Parties</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">21</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">8.5. Pharmacovigilance / Drug Safety Matters</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">21</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:30px; text-indent:-15px">9. PATENTS and Updated Technology</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">22</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">9.1. Updated Technology</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">22</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">9.2. Rights to Improvements</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">22</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">9.3. Application and Maintenance of Patents</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">22</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">9.4. No Warranty</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">23</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">9.5. Infringement by Third Party</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">23</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">9.6. Infringement Alleged by Third Party</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">24</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:30px; text-indent:-15px">10. RECORDS</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">24</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">10.1. Records</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">24</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">10.2. Examination by Certified Public Accountant</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">24</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:30px; text-indent:-15px">11. TAXATION</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">25</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">11.1. Responsibility for Tax</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">25</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">11.2. Withholding Tax</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">25</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:30px; text-indent:-15px">12. FINANCIAL MATTERS</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">25</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">12.1. Late Payments</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">25</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">12.2. Manner of Payment</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">25</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:30px; text-indent:-15px">13. CONFIDENTIALITY</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">26</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">13.1. Non-disclosure</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">26</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">13.2. Limited Purposes</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">26</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">13.3. Exceptions</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">26</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:60px; text-indent:-15px">13.3.1. Information Otherwise Available</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">26</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:60px; text-indent:-15px">13.3.2. Governmentally Required Disclosures</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">26</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">13.4. Publication Procedure</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">27</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">13.5. Return of Information</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">27</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">13.6. Additional Permitted Disclosures</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">27</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">13.7. Terms and Conditions of this Agreement</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">27</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">13.8. Previous Confidential Agreement</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">27</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:30px; text-indent:-15px">14. TERM AND TERMINATION</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">28</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">14.1. Expiration</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">28</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">14.2. Termination by CONFORMA</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">28</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">14.3. Termination for Breach</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">28</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">14.4. Termination for Bankruptcy</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">28</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">14.5. Termination for Patent Challenge</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">28</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">14.6. Termination for Change of Control</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">28</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">14.7. Consequences of Termination</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">29</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:60px; text-indent:-15px">14.7.1. Responsibilities of CONFORMA</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">29</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:60px; text-indent:-15px">14.7.2. Responsibilities of SUMITOMO</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">29</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:60px; text-indent:-15px">14.7.3. Regulatory Responsibilities of Both Parties</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">29</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:60px; text-indent:-15px">14.7.4. Ancillary Agreements</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">29</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">14.8. Outstanding Payments</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">29</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">14.9. Survival Clauses</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">29</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:30px; text-indent:-15px">15. INDEMNIFICATION</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">30</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">15.1. Indemnification by SUMITOMO</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">30</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">15.2. Indemnification by CONFORMA</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">30</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">15.3. Procedure</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">31</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">15.4. No Lost Profit</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">31</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:30px; text-indent:-15px">16. REPRESENTATIONS, WARRANTIES AND COVENANTS</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">31</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">16.1. Execution of Agreement</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">31</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">16.2. Additional SUMITOMO Representations</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">32</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">16.3. Material Facts</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">32</TD>
    <TD>&nbsp;</TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>


<P align="center" style="font-size: 10pt"><!-- Folio -->&nbsp;<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
<!-- Begin Table Head -->
<TR valign="bottom">
    <TD width="88%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="3%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="3%">&nbsp;</TD>
</TR>
<!-- End Table Head -->
<!-- Begin Table Body -->
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">16.4. Manufacture of Compound and Product</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">32</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">16.5. Express Warranties</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">32</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:30px; text-indent:-15px">17. MISCELLANEOUS PROVISIONS</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">33</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">17.1. Headings</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">33</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">17.2. Severability</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">33</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">17.3. Entire Agreement; Amendment</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">33</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">17.4. Assignability</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">33</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">17.5. Independent Party</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">33</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">17.6. Notice and Reports</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">33</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">17.7. Waiver</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">34</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">17.8. Force Majeure</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">34</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">17.9. Dispute Resolution and Arbitration</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">34</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">17.10. Applicable Law</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">35</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">17.11. Language</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">35</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:45px; text-indent:-15px">17.12. Counterparts</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">35</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">Annex 1.6</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">37</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">Annex 1.27</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">38</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">Annex 1.30</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">39</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">Annex 4.2.3</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">40</TD>
    <TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD><DIV style="margin-left:15px; text-indent:-15px">Annex 16.2</DIV></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="right">41</TD>
    <TD>&nbsp;</TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>


<P align="center" style="font-size: 10pt"><!-- Folio -->&nbsp;<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>



<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">This License Agreement is executed on this June&nbsp;23, 2005, by and between
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 12pt"><B>SUMITOMO PHARMACEUTICALS Co., Ltd.</B>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">a company duly established under the laws of Japan and having its principal place of business at
12-2, Kyobashi 1-chome, Chuo-ku, Tokyo, 104-8356, Japan (hereinafter &#147;SUMITOMO&#148;)
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">and
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 12pt"><B>Conforma Therapeutics Corporation</B>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">a company duly established under the laws of Delaware, USA and having its principal place of
business at 9393 Towne Centre Drive, Suite&nbsp;240, San Diego, CA, USA (hereinafter &#147;CONFORMA &#147;)
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 12pt"><U><B>RECITALS</B></U>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">WHEREAS, SUMITOMO has developed and commercialized a certain anti-cancer drug (&#147;Product&#148; as defined
in Section&nbsp;1) containing a compound known as Amrubicin Hydrochloride or SM-5887 (&#147;Compound&#148; as
defined in Section&nbsp;1) in Japan;
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">WHEREAS, SUMITOMO desires to develop and commercialize the Product also in countries other than
Japan through licensing;
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">WHEREAS, CONFORMA has an interest in the development of the Product in North America and European
countries (&#147;Territory&#148; as defined in Section&nbsp;1) and has an interest in obtaining rights to develop
and market the Product there;
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">WHEREAS, SUMITOMO and CONFORMA have exchanged certain information under the Confidential Disclosure
Agreement on Amrubicin dated August&nbsp;12, 2004 in order to evaluate the possibility of business
collaboration on the Product;
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">WHEREAS, CONFORMA, as a result of above evaluation, desires to receive certain rights to develop
and commercialize the Product in the Territory and SUMITOMO desires to grant such rights to
CONFORMA;
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">NOW THEREFORE, in consideration hereof, the Parties hereby agree as follows:
</DIV>


<DIV style="margin-top: 12pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><U><B>1.</B></U>&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD> <U><B>DEFINITIONS</B></U></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>As used herein, the following terms shall have the respective meanings set forth below
unless the context clearly requires other meanings</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.1.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Affiliate&#148; </B>or <B>&#147;Affiliates&#148; </B>shall mean any corporation or business entity controlling,
controlled by or under common control with a Party to this Agreement. For the purpose of the
foregoing, &#147;control&#148; shall mean the direct or indirect ownership of more than fifty percent
(50%) of the voting stock in such corporation or other entity, or the <I>de facto </I>decision-making
power in such corporation or entity</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.2.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Annex&#148; </B>or <B>&#147;Annexes&#148; </B>shall mean any document attached to this Agreement with the title of
&#147;Annex&#148; which constitutes a part of this Agreement and is legally binding.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.3.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Authorization&#148; </B>shall mean an approval or a permit to market the Product, including</TD>
</TR>

</TABLE>
</DIV>
<P align="right" style="font-size: 10pt"><!-- Folio -->page 1<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">


<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>pricing and reimbursement approval where required, in any of the countries within the
Territory which is granted by the Regulatory Authority.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.4.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Combination Product&#148; </B>shall mean a Finished Product sold by CONFORMA, its Affiliates or its
Sublicensees that contains a Compound together with at least one other active pharmaceutical
ingredient.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.5.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Commercially Reasonable Efforts&#148; </B>shall mean efforts consistent with those generally utilized
by companies of a similar size for their own internally developed pharmaceutical products of
similar market potential, at a similar stage of their product life taking into account the
existence of other competitive products in the market place or under development, the
proprietary position of the product, the regulatory structure involved, the anticipated
profitability of the product and other relevant factors. It is understood that such product
potential may change from time to time based upon changing scientific, business and marketing
and return on investment considerations.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.6.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Compound&#148; </B>shall mean the compound known as Amrubicin (international nonproprietary name)
hydrochloride which is generically known as (&#043;)-(7S,
9S)-9-acetyl-9-amino-7-&#091;(2-deoxy-<font face="symbol">&#098;</font>-D-erythro-pentopyranosyl)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;

oxy&#093;-7,8,9,<BR>10-tetrahydro-6,11-dihydroxy-5,12-naphthacenedione hydrochloride as more fully
described in Annex 1.6 hereto.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.7.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Control&#148; </B>or <B>&#147;Controlled by&#148; </B>shall mean, with respect to any item of Information, Patent or
Know-how, possession of the right, whether directly or indirectly, and whether by ownership,
license or otherwise, to assign, or grant a license, sublicense or other right to or under,
such Information, Patent or Know-how as provided for herein without violating the terms of any
agreement or other arrangement with any Third Party.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.8.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Data Protection&#148; </B>shall mean certain data exclusivity and market exclusivity available to the
Product under a pharmaceutical law, regulation or any other governmental decree or order of a
certain country within the Territory.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.9.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Development&#148; </B>in the Territory shall mean all the activities necessary to obtain the
Authorization, including, but not limited to, pre-clinical studies, clinical studies, and
preparation of the documents for the submission to the Regulatory Authority.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.10.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Effective Date&#148; </B>shall mean the date on which this Agreement is executed.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.11.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;EMEA&#148; </B>shall mean the European Medicines Agency, or any successor regulatory authority in
Europe.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.12.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Europe&#148; </B>shall mean the countries comprising the European Union on the date of the first
submission for the Authorization of the Product to EMEA or to the Regulatory Authorities of
one of the Major European Countries.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.13.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Finished Product&#148; </B>shall mean a packaged and labeled Product for commercial sale under
Authorization.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.14.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Generic Product(s)&#148; </B>shall mean any pharmaceutical products having the same active
pharmaceutical ingredient and sold for the same indication and in same dosage form as the
Compound.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.15.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Generic Product Entry&#148; </B>shall mean, for a given country of the Territory, the first day of
the first calendar quarter for which publicly reported quantity of sales in units of Generic
Product(s) during such quarter exceed twenty percent (20%) of the aggregate quantity of all
units of Generic Product(s) and Product sold in the relevant country during the same
calendar quarter.</TD>
</TR>


</TABLE>
</DIV>
<P align="right" style="font-size: 10pt"><!-- Folio -->page 2<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">


<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.16.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Improvements&#148; </B>shall mean, whether patentable or not, new compositions and processes
pertaining directly to the Compound and/or the Product, or new techniques of using, applying,
administering, or manufacturing the Compound and/or the Product which are owned or Controlled
by CONFORMA or its Affiliates during the term of this Agreement.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.17.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;IND&#148; </B>shall mean an investigational new drug application filed with the FDA for
authorizations to commence human clinical trials, or its equivalent in other countries within
the Territory, as applicable.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.18.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Initial Period&#148; </B>shall mean, on a country-by-country basis and on a Product-by-Product
basis, the period from the Effective Date through the later of:</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="5%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(a)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>the end of the calendar month following the tenth (10th) anniversary of the
Launch; or</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(b)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>the Generic Product Entry.</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.19.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Know-how&#148; </B>shall mean, whether patentable or not, all the proprietary information or data
related to the research and development of the Compound and/or the Product, or those related
to the marketing, using, sale or distribution of the Finished Product which is owned or
Controlled by SUMITOMO or its Affiliates as of the Effective Date or during the term of this
Agreement, including without limitation all the data, documentation and other information
contained in or making up the regulatory filings made by SUMITOMO or its Affiliates for the
Product outside the Territory.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.20.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Launch&#148; </B>shall mean, on a county-by-country basis, the date of the first commercial sale of
the Finished Product by CONFORMA, its Affiliate or its Sublicensee in a given country after
Authorization in such country. For the avoidance of doubt, the first commercial sale of the
Finished Product shall mean the date on which CONFORMA, its Affiliates, and/or the Sublicensee
ship the first Finished Product in such given country to distributors, wholesalers or other
end users.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.21.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Licensee&#148; </B>shall mean any company or legal entity other than SUMITOMO&#146;s Affiliates which is
granted by SUMITOMO a right to import, use, develop, register, market, promote, distribute
and/or sell the Compound and/or the Product outside the Territory.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.22.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Major European Countries&#148; </B>shall mean any or all of the United Kingdom, Germany, France,
Spain and Italy.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.23.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Manufacturing Technology&#148; </B>shall mean all methods, processes, technology, information, data,
results of tests, studies, and analyses, whether patentable or not which are specifically
related to the manufacturing process of the Compound and/or Product, owned or Controlled by
SUMITOMO or its Affiliates as of the Effective Date or during the term of this Agreement.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.24.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;NDA&#148; </B>shall mean a new drug application filed with the FDA for authorization to market a
pharmaceutical product or its equivalent in other countries within the Territory, as
applicable.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.25.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Net Sales&#148; </B>shall be defined as the gross amount invoiced by CONFORMA, its Affiliates,
and/or its Sublicensees upon sales of the Finished Product to unaffiliated Third Parties, less
the following items pertaining to such Finished Product, consistent with U.S. GAAP:</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="5%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(a)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>trade quantity and cash discounts actually allowed;</TD>
</TR>

</TABLE>
</DIV>
<P align="right" style="font-size: 10pt"><!-- Folio -->page 3<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">


<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="5%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(b)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>commissions, discount, refunds, rebates, charge backs, retroactive price
adjustment, and any other allowance paid to Third Parties that effectively reduce net
selling price;</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(c)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>actual Finished Product returns and allowances;</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(d)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>freight, shipping, packing, and insurance charges;</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(e)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>use, sales or other taxes, duties or tariffs applicable to the import, export
or sale of Finished Products (excluding taxes based on the selling party&#146;s income);
and</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(f)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>any other similar or customary deductions, as consistent with U.S. GAAP.</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.26.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Party&#148; </B>shall mean SUMITOMO or CONFORMA and &#147;Parties&#148; shall mean SUMITOMO and CONFORMA.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.27.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Patent&#148; </B>or <B>&#147;Patents&#148; </B>shall mean any or all patents and patent applications filed or owned
or Controlled by SUMITOMO or its Affiliates as of the Effective Date or during the term of
this Agreement in any country within the Territory which cover the Compound, the Product, the
Finished Product and/or its use, including any continuation, continuation in part, divisional
or reissue patent application(s), re-examinations, renewals, substitutions, provisionals,
inventor&#146;s certificates or patent addition(s), or patent(s) filed thereon and any extension(s)
thereof (by way of example, an extension by supplementary protection certificate) and any
patents issuing therefrom; provided, however, that in the event any claimed invention
theretofore covered by the Patents shall no Ionger be covered thereby for any reason
whatsoever, including expiration, renunciation, abandonment, disclaimer, withdrawal, failure
to maintain, or an adjudication of invalidity by a court of competent jurisdiction from the
judgment of which no further appeal can be taken, such invention shall be deemed automatically
excluded from the term &#147;Patents&#148; to such extent. Annex 1.27 is the list of the Patents as of
the Effective Date which is to be updated from time to time by mutual agreement.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.28.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Product&#148; </B>shall mean pharmaceutical products for human use containing the Compound as a
pharmaceutically active ingredient in unlabeled vial.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.29.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Regulatory Authority&#148; </B>shall mean the governmental organization or the
administrative body subject to state supervision which has authority to regulate
pharmaceutical affairs in a country within the Territory, and more specifically, which has
authority to grant marketing authorizations for pharmaceutical products and/or authority to
decide prices of pharmaceutical products in such country.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.30.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Specifications&#148; </B>shall mean, after the NDA filing in the USA, those specifications for the
Product mutually agreed upon by the Parties and set forth in the NDA filed in the USA. Prior
to such application, Specifications shall refer to the specifications for the Product as
tested mutually agreed upon by the Parties and pursuant to the IND opened in the USA. Prior
to the IND, Specifications shall refer to the specifications for the Product described in
Annex 1.30, which may be changed or modified with the prior written agreement of the Parties.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.31.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Sublicensee&#148; </B>shall mean any company or legal entity other than CONFORMA&#146;s Affiliates which
is sublicensed by CONFORMA all or a part of CONFORMA&#146;s rights granted hereof.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.32.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Supply Agreement&#148; </B>shall have the meaning ascribed to it in Section&nbsp;6.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.33.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Territory&#148; </B>shall mean North America and Europe.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.34.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Third Party&#148; </B>or <B>&#147;Third Parties&#148; </B>shall mean any or all persons or entities other than (a)</TD>
</TR>

</TABLE>
</DIV>
<P align="right" style="font-size: 10pt"><!-- Folio -->page 4<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">
<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>



<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">


<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>SUMITOMO, any of its Affiliates or Licensees or (b)&nbsp;CONFORMA, any of its Affiliates or
Sublicensees.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>1.35.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#147;Trademark&#148; </B>or <B>&#147;Trademarks&#148; </B>shall mean any or all trademarks or tradenames to be selected by
CONFORMA pursuant to Section&nbsp;7.1. for use on and in connection with the Finished Product in
the Territory.</TD>
</TR>

</TABLE>
</DIV>
<P align="right" style="font-size: 10pt"><!-- Folio -->page 5<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>


<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">


<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><U><B>2.</B></U>&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD> <U><B>GRANT OF RIGHTS </B></U></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>2.1.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Exclusive Right</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Subject to the terms and conditions of this Agreement, SUMITOMO (on behalf of itself and its
Affiliates) hereby grants to CONFORMA and CONFORMA hereby accepts an exclusive right and
license (even as to SUMITOMO and its Affiliates), with a right to sublicense as set forth in
Section&nbsp;2.2, under the Patents and the Know-how (a)&nbsp;to import and use the Compound and the
Product, (b)&nbsp;to develop, register, import, use, market, promote, distribute and sell the
Product or Finished Product, and (c)&nbsp;to use the Trademark, each of (a), (b)&nbsp;and (c)&nbsp;within
the Territory. The right and license granted to CONFORMA under this Section&nbsp;2.1. excludes
the right to manufacture the Compound and the Product in Initial Period.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>2.2.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Sublicense</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>CONFORMA may sublicense its rights hereof to its Affiliates and/or a Third Party, provided
that in case of sublicense to a Third Party, CONFORMA shall obtain SUMITOMO&#146;s prior written
consent which shall not be unreasonably withheld, conditioned or delayed. CONFORMA shall
ensure that any such Sublicensee complies with at least the same obligations as CONFORMA
assumes under this Agreement and the Supply Agreement, and CONFORMA shall make to SUMITOMO
the same milestone payments, bonus payments, payment for the Product, royalties for the
Manufacturing Technology and the Trademark license, as those which CONFORMA should pay if it
developed or marketed the Product by itself.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>2.3.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>License Grant Back to SUMITOMO</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>CONFORMA grants to SUMITOMO a non-exclusive, perpetual, royalty-free license, with a right
to sublicense, of the Improvements to develop, register, manufacture, import, use, market,
promote, distribute and sell the Compound and/or Product outside the Territory.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>During the term of this Agreement, CONFORMA shall advise SUMITOMO as soon as
commercially reasonable of any Improvements necessary or useful for the development or
commercialization of the Product outside the Territory.</TD>
</TR>

<TR>
    <TD style="font-size: 12pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><U><B>3.</B></U></TD>
    <TD width="1%">&nbsp;</TD>
    <TD> <U><B>CONSIDERATION</B></U></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>In partial consideration of the rights and licenses granted to CONFORMA hereof, CONFORMA
shall pay SUMITOMO according to the schedule set forth in Section&nbsp;3.1 and 3.2. The
remaining consideration shall be paid as a part of the Purchase Price and as a royalty for
the Trademark according to the Supply Agreement and Section&nbsp;7.4. of this Agreement,
respectively.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>3.1.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Up-front and Milestone Payments</B></TD>
</TR>

</TABLE>
</DIV>
<DIV align="left" style="font-size: 10pt; margin-top: 6pt">CONFORMA shall pay to SUMITOMO, up to a total amount of <B>&#091;***&#093; </B>US Dollars
(US$ <B>&#091;***&#093;</B>) within thirty (30)&nbsp;days after the first occurrence of the following events:
</DIV>

<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
<!-- Begin Table Head -->
<TR valign="bottom">
    <TD width="88%">&nbsp;</TD>
    <TD width="2%">&nbsp;</TD>
    <TD width="10%">&nbsp;</TD>
</TR>
<TR style="font-size: 8pt" valign="bottom">
    <TD nowrap align="left" style="border-bottom: 1px solid #000000">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&#091;Events&#093;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</TD>
    <TD style="border-bottom: 1px solid #000000">&nbsp;</TD>
    <TD nowrap align="center" style="border-bottom: 1px solid #000000">&#091;Payments&#093;</TD>
</TR>

<!-- End Table Head -->
<!-- Begin Table Body -->
<TR valign="bottom" style="background: #cceeff">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">(i) On signing:
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">USD <B>&#091;***&#093; </B>million</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">(ii) Upon first-patient-in of the first clinical trial
of the Product sponsored by CONFORMA:
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">USD <B>&#091;***&#093; </B>million</TD>
</TR>
<TR valign="bottom" style="background: #cceeff">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">(iii) On receipt of Authorization in the USA:
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="left" valign="top">USD <B>&#091;***&#093; </B>million</TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">(iv) On receipt of first Authorization in Europe:
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="left" valign="top">USD <B>&#091;***&#093; </B>million</TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>
<DIV align="left">
<DIV style="font-size: 3pt; margin-top: 16pt; width: 18%; border-top: 1px solid #000000">&nbsp;</DIV>
</DIV>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
<TR>
    <TD width="3%"></TD>
    <TD width="1%"></TD>
    <TD width="96"></TD>
</TR>

<TR valign="top">
    <TD nowrap align="left"><B>***</B></TD>
    <TD>&nbsp;</TD>
    <TD><B>Confidential Treatment Requested</B></TD>
</TR>

</TABLE>


<P align="right" style="font-size: 10pt"><!-- Folio -->page 6<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>


<DIV style="font-family: Helvetica,Arial,sans-serif">
<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>3.2.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Bonus Payments</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>CONFORMA shall pay to SUMITOMO the following one-time bonus payments within ninety (90)
days from the end of the first calendar year in which total annual Net Sales in the
Territory exceeds:</TD>
</TR>

</TABLE>
</DIV>
<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
<!-- Begin Table Head -->
<TR valign="bottom">
    <TD width="88%">&nbsp;</TD>
    <TD width="2%">&nbsp;</TD>
    <TD width="10%">&nbsp;</TD>
</TR>
<TR style="font-size: 8pt" valign="bottom">
    <TD nowrap align="left" style="border-bottom: 1px solid #000000">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&#091;Events&#093;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</TD>
    <TD style="border-bottom: 1px solid #000000">&nbsp;</TD>
    <TD nowrap align="center" style="border-bottom: 1px solid #000000">&#091;Payments&#093;</TD>
</TR>

<!-- End Table Head -->
<!-- Begin Table Body -->
<TR valign="bottom" style="background: #cceeff">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">(i) USD 25&nbsp;million:
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="left" valign="top">USD <B>&#091;***&#093; </B>million</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">(ii) USD 50&nbsp;million
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">USD <B>&#091;***&#093; </B>million</TD>
</TR>
<TR valign="bottom" style="background: #cceeff">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">(iii) USD 100&nbsp;million
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">USD <B>&#091;***&#093; </B>million</TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>


<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>In case foregoing two events occur in the same calendar year, CONFORMA shall pay both
bonus payments to SUMITOMO at the same time.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>3.3.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Sublicensee Payments</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>In the event that CONFORMA receives any up-front or milestone payments, excluding equity
investment or reimbursement of expenses, from its Sublicensee as a consideration of the
sublicense of CONFORMA&#146;s rights granted hereof, (a)&nbsp;if received by CONFORMA during the
period from the Effective Date through the Launch (the &#147;Development Period&#148;), CONFORMA shall
pay to SUMITOMO <B>&#091;***&#093; </B>percent (<B>&#091;***&#093;</B>%) of any such amounts received
during the Development Period within thirty (30)&nbsp;days of receipt; and (b)&nbsp;if received by
CONFORMA after the last day of the Development Period, the amount of such payments shall be
deemed to be Net Sales.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>3.4.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Non-Refundability</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Unless otherwise agreed in this Agreement, all the payments set forth in this Section&nbsp;3 are
non-refundable once they have been paid, and are not creditable to other payment obligations
of CONFORMA.</TD>
</TR>

<TR>
    <TD style="font-size: 12pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><U><B>4.</B></U>&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD> <U><B>DEVELOPMENT</B></U></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>4.1.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Technology Transfer</B></TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(i)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>As soon as commercially reasonable after the Effective Date of this Agreement,
SUMITOMO shall disclose and make available to CONFORMA, free of charge, all the
Know-how to the extent necessary or useful to the Development.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(ii)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>CONFORMA shall provide SUMITOMO, free of charge, with the following information
which CONFORMA, its Affiliates, and its Sublicensees obtain from the Development or
marketing activities in the Territory, as soon as commercially reasonable after
CONFORMA acquires such information, or if specifically so designated below, at
SUMITOMO&#146;s request:</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="8%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">a)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>abstracts and summaries of the Development data, and at SUMITOMO&#146;s
request, copies thereof,</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="6%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">b)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>copies of documents submitted to or filed with the Regulatory Authority,</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="6%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">c)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>safety and efficacy data,</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="6%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">d)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>new indication or new formulation which may be applied to the Product.</TD>
</TR>

</TABLE>
</DIV>


<DIV align="left">
<DIV style="font-size: 3pt; margin-top: 16pt; width: 18%; border-top: 1px solid #000000">&nbsp;</DIV>
</DIV>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
<TR>
    <TD width="3%"></TD>
    <TD width="1%"></TD>
    <TD width="96"></TD>
</TR>

<TR valign="top">
    <TD nowrap align="left"><B>***</B></TD>
    <TD>&nbsp;</TD>
    <TD><B>Confidential Treatment Requested</B></TD>
</TR>

</TABLE>


<P align="right" style="font-size: 10pt"><!-- Folio -->page 7<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>


<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>






<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="5%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Subject to Section&nbsp;13 of this Agreement, SUMITOMO, its Affiliates and its Licensees
shall be free to use the foregoing information provided by CONFORMA for the purposes of
developing or marketing the Product outside the Territory, pursuant to Section&nbsp;2.3.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(iii)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>SUMITOMO shall provide CONFORMA, free of charge, with the following
information which SUMITOMO, its Affiliates and its Licensees obtain from the
development or marketing activities outside the Territory, as soon as commercially
reasonable after SUMITOMO acquires such information, or if specifically so designated
below, at CONFORMA&#146;s request:</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="7%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">a)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>abstracts and summaries of the development data, at CONFORMA&#146;s request,
copies thereof,</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="6%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">b)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>copies of documents submitted to or filed with regulatory authorities
outside the Territory, at CONFORMA&#146;s request,</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="6%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">c)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>safety and efficacy data,<BR></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="6%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">d)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>new indication or new formulation which may be applied to the Product.</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Subject to Section&nbsp;13 of this Agreement, CONFORMA, its Affiliates and its
Sublicensees shall be free to use the foregoing information provided by SUMITOMO for the
purposes of developing or marketing the Product in the Territory, pursuant to Sections
2.1 and 2.2.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="5%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(iv)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>SUMITOMO shall disclose the Manufacturing Technology only to the extent
necessary for CONFORMA to obtain Authorization in the Territory. In connection with
the foregoing, if SUMITOMO establishes and maintains a Drug Master File (&#147;DMF&#148;) with
the Regulatory Authority, SUMITOMO grants CONFORMA, its Affiliates and its Sublicensees
a right to reference to the data included in the DMF for incorporation into the NDA and
agrees to provide such further written authorizations as may be required to effectuate
this right of reference.</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>4.2.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Implementation of Development</B></TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="5%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"><B>4.2.1.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Implementation of Development</B></TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>CONFORMA shall have the sole responsibility for conducting the clinical Development in the
Territory. The cost of clinical Development in the Territory shall be borne by CONFORMA.
The cost of non-clinical Development activities in the Territory initiated by CONFORMA after
the Effective Date shall be borne by CONFORMA.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>CONFORMA undertakes to give SUMITOMO progress reports of the Development on a semi annual
basis covering items such as the status of recruitment and registration of the patients, the
result of each trial and the status of preparation of the regulatory documents for IND or
NDA.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>It is understood and agreed that SUMITOMO has a right to participate in the investigators
meetings held in the Territory and in the meetings with Regulatory Authorities in the
Territory, provided that SUMITOMO&#146;s participation shall be passive and without a right to
comment.</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="5%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"><B>4.2.2.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Joint Steering Committee</B></TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>In order to facilitate the development of the Product and share the information and
coordinate each Party&#146;s development activities in and outside the Territory, CONFORMA
and</TD>
</TR>

</TABLE>
</DIV>
<P align="right" style="font-size: 10pt"><!-- Folio -->page 8<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">
<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>



<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">


<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>SUMITOMO shall organize and hold a Joint Steering Committee meeting at least twice in each
calendar year but no more than four times a year, unless required by exceptional
circumstances. The meetings will be held in the form of face-to-face meeting,
teleconference or videoconference. The Joint Steering Committee shall consist of two (2)
representatives of each Party. The Parties shall hold the first Joint Steering Committee
meeting within sixty (60)&nbsp;days of the Effective Date.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The Joint Steering Committee shall have responsibility to:</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(i)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>discuss the development plan (including any revisions thereof) for the Product
in the Territory, with the general time schedule (&#147;Development Plan&#148; as more fully
described in Section&nbsp;4.2.3.);</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(ii)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>discuss protocols of clinical studies for the Development;</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(iii)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>ensure the appropriate sharing of data and information relating to the
Development of the Product in the Territory and the development of the Product outside
the Territory;</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(iv)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>review and evaluate CONFORMA&#146;s Development activities and the Development
efforts, including but not limited to the Development strategy and study protocols;</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(v)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>discuss the coordination of each Party&#146;s respective Development activities
relating to the Product;</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(vi)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>discuss a coordinated publication strategy for the Product;</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(vii)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>review the requirements of the Compound and the Product for the Development by
CONFORMA, including forecasts thereof; and</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(viii)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>discuss the expansion of indications, Improvements and life cycle management.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"><B>4.2.3.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Development Plan</B></TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>CONFORMA shall have the sole responsibility for designing and implementing the Development
Plan in the Territory provided that such design and implementation is done using
Commercially Reasonable Efforts. CONFORMA shall have the final decision making right with
respect to the Development Plan, provided that such decisions are made in a commercially
reasonable manner and that CONFORMA presents the draft of the Development Plan to SUMITOMO
at least thirty (30)&nbsp;days prior to the Joint Steering Committee meetings, explains the draft
to SUMITOMO and refers to SUMITOMO&#146;s comments and opinions in the Joint Steering Committee
meetings before finalizing the Development Plan, and provided further that in the event of a
material delay in the Development, SUMITOMO has the rights described below.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The Development Plan shall contain an estimated timeline for clinical studies and the filing
of NDA or its equivalent documents in the Territory <B>&#091;***&#093;</B>.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The draft for the Development Plan as of the Effective Date is attached hereto as Annex
4.2.3.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>CONFORMA shall use Commercially Reasonable Efforts to implement the Development Plan,
contingent on SUMITOMO fulfilling its obligations under Sections&nbsp;4.1(i), 4.1(iii) and 4.3.1
of this Agreement. Any revision of the Development Plan requires the discussions in the
Joint Steering Committee meetings as described above.<BR></TD>
</TR>

</TABLE>
</DIV>

<DIV align="left">
<DIV style="font-size: 3pt; margin-top: 16pt; width: 18%; border-top: 1px solid #000000">&nbsp;</DIV>
</DIV>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
<TR>
    <TD width="3%"></TD>
    <TD width="1%"></TD>
    <TD width="96"></TD>
</TR>

<TR valign="top">
    <TD nowrap align="left"><B>***</B></TD>
    <TD>&nbsp;</TD>
    <TD><B>Confidential Treatment Requested</B></TD>
</TR>

</TABLE>

<P align="right" style="font-size: 10pt"><!-- Folio -->page 9<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">


<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>If CONFORMA foresees or becomes aware of any material delay in the Development Plan that
would delay the planned NDA filing date, CONFORMA shall provide SUMITOMO with a description
of the nature of the delay and a revised Development Plan within thirty (30)&nbsp;days after
becoming aware of such delay and CONFORMA and SUMITOMO shall hold a Joint Steering Committee
meeting within thirty (30)&nbsp;days thereafter.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>If there is a material delay in the implementation of the Development Plan and CONFORMA is
not able to demonstrate to SUMITOMO&#146;s reasonable satisfaction that it used Commercially
Reasonable Efforts in carrying out the Development Plan under this Section&nbsp;4.2.3., SUMITOMO
may terminate the rights granted to CONFORMA under thisAgreement pursuant to Section&nbsp;14.3.
However, in case such material delay would occur only in Europe, SUMITOMO may terminate this
Agreement only with respect to Europe, and upon such termination, all the member states of
the Europe shall be excluded from the Territory.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>If the delay is attributable to CONFORMA&#146;s negligence or willful misconduct with respect to
Section&nbsp;4.2.3, SUMITOMO may, at its discretion, terminate this Agreement in its entirety
pursuant to Section&nbsp;14.3., but upon shorter notice period of thirty (30)&nbsp;days.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>In addition to the draft of the Development Plan, CONFORMA shall send to SUMITOMO all the
draft of the study protocols before finalization and refer to SUMITOMO&#146;s comment.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>4.3.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Clinical Supplies for Development</B></TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="5%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"><B>4.3.1.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Supply of Product</B></TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>SUMITOMO shall supply CONFORMA, its Affiliates&#146; and/or Sublicensees&#146; with their requirements
for Product for use in Development. Product supplied by SUMITOMO for Development purposes
shall be provided free of charge in quantities not to exceed eight thousand (8000)&nbsp;50mg
vials. If CONFORMA requires supplies of the Product in excess of this amount, SUMITOMO
shall supply such excess amounts of Product to CONFORMA at the Minimum Price as defined in
Section&nbsp;6.2.1 or the Supply Agreement.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>CONFORMA shall place its first order for clinical supplies no later than thirty (30)&nbsp;days
following the Effective Date, to be delivered no later than January&nbsp;15, 2006. CONFORMA
shall place subsequent orders for clinical supplies at least six (6)&nbsp;months prior to the
desired delivery date. SUMITOMO will use commercially reasonable efforts to meet CONFORMA&#146;s
requested quantities and delivery dates. SUMITOMO shall notify CONFORMA of the specific
delivery date and quantity for each subsequent order no later than (2)&nbsp;months following
CONFORMA&#146;s order.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Additionally, SUMITOMO shall use commercially reasonable efforts to deliver one hundred
(100)&nbsp;50mg vials of Product no later than September&nbsp;30, 2005 which CONFORMA will use for the
purposes of certifying Third Parties who will conduct release testing, labeling and
packaging.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The trade term which applies to the transaction of the Compound and the Product under this
Section&nbsp;4.3 shall be FCA (INCOTERMS 2000) Kansai International Airport, Japan.</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="5%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"><B>4.3.2.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Specifications</B></TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>All the Product for clinical trials supplied by SUMITOMO shall conform to the Specifications
and cGMP of the USA.</TD>
</TR>

</TABLE>
</DIV>
<P align="right" style="font-size: 10pt"><!-- Folio -->page 10<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">
<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>



<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">



</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="5%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"><B>4.3.3.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Labeling and Packaging</B></TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>CONFORMA shall label and package the Product for Development.</TD>
</TR>

<TR>
    <TD style="font-size: 12pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>5.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><U><B>MARKETING AND PROMOTION</B></U></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>5.1.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Commercially Reasonable Efforts to Market</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>CONFORMA shall use Commercially Reasonable Efforts to commercialize the Finished
Product in the Territory as soon as reasonably practicable given applicable business and
market conditions and the regulatory environment and contingent on SUMITOMO fulfilling its
obligations under Sections&nbsp;4.1.(i) and 4.1.(iii) of this Agreement and to supply the
Product under Section&nbsp;6 or the Supply Agreement.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>5.2.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Commercialization Plan</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Within sixty (60)&nbsp;days after completion of the last clinical trial for the NDA for the first
country in which an NDA is to be made, CONFORMA shall provide SUMITOMO with a three (3)&nbsp;year
commercialization plan (&#147;Commercialization Plan&#148;) which will be updated by the end of third
quarter every year. The Commercialization Plan shall include CONFORMA&#146;s launch plans, such
as publication planning, opinion development, positioning and pricing strategies, campaign
development and annual marketing strategy for the Product as well as annual sales forecast
of the Product in value separately for North America and Europe. CONFORMA&#146;s
commercialization plans shall set forth that CONFORMA will launch the Finished Product in
the USA within three (3)&nbsp;months from the date on which the Authorization is granted in the
USA and launch the Finished Product at least in three of five Major European Countries
within one (1)&nbsp;year after receipt of Authorization in each such country.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>If CONFORMA foresees or becomes aware of any material delay in the commercialization plan
that would delay the actual Launch date of the Finished Product more than ninety (90)&nbsp;days,
CONFORMA will provide SUMITOMO with a description of the nature of the delay and a revised
Annual Commercialization Plan for the impacted countries within sixty (60)&nbsp;days after
becoming aware of such delay.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>If CONFORMA is not able to demonstrate to SUMITOMO&#146;s reasonable satisfaction that there are
reasonable commercial reasons for the material delay of the Launch date such as reasons
related to pricing and reimbursement, SUMITOMO may terminate the rights granted to CONFORMA
under this Agreement pursuant to Section&nbsp;14.3. However, in case such material delay would
occur only in Europe, SUMITOMO may terminate this Agreement only with respect to Europe, and
upon such termination, all the member states of the Europe shall be excluded from the
Territory</TD>
</TR>


<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>
If the delay is attributable to CONFORMA&#146;s negligence or willful misconduct with respect to
this Section&nbsp;5.2., SUMITOMO may, at its discretion, terminate this Agreement in its entirety
pursuant to Section&nbsp;14.3., but upon shorter notice period of thirty (30)&nbsp;days.</TD>
</TR>


</TABLE>
</DIV>
<P align="right" style="font-size: 10pt"><!-- Folio -->page 11<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">



</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>5.3.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Minimum Sales</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>CONFORMA shall achieve the minimum sales which is seventy percent (70%) of the annual sales
forecast as specified in the Commercialization Plan (&#147;Minimum Sales&#148;). For the purpose of
defining CONFORMA&#146;s Minimum Sales requirement, only the sales forecast specified in the
latest Commercialization Plan prior to the start of the relevant calendar year shall be
binding, and with respect to the Minimum Sales requirement for the period covering the first
Launch in the Territory to December&nbsp;31<SUP style="font-size: 85%; vertical-align: text-top">st</SUP> of such year, CONFORMA may update the
sales forecast by the time of the expected Authorization date in the USA. If CONFORMA fails
to achieve the Minimum Sales for any consecutive two (2)&nbsp;calendar years in North America or
Europe, SUMITOMO may, at its discretion, terminate this Agreement pursuant to Section&nbsp;14.3.
or convert CONFORMA&#146;s exclusive license to non-exclusive upon thirty (30)&nbsp;days&#146; written
notice with respect to the area where CONFORMA cannot achieve the Minimum Sales (i.e., North
America or Europe); provided, however, that CONFORMA may, in lieu of such termination or
conversion, agree prior to the expiration of such thirty (30)&nbsp;day period to pay to SUMITOMO
an amount equal to the Minimum Sales minus the actual sales during the relevant period
multiplied by <FONT style="font-size: 70%"><SUP>1</SUP></FONT>/<FONT style="font-size: 60%">2</FONT> of the Calculated Price (e.g., <FONT style="font-size: 70%"><SUP>1</SUP></FONT>/<FONT style="font-size: 60%">2</FONT> of <B>&#091;***&#093;</B>% or <FONT style="font-size: 70%"><SUP>1</SUP></FONT>/<FONT style="font-size: 60%">2</FONT> of
<B>&#091;***&#093;</B>%, as the case may be). For the avoidance of doubt, if the Minimum Sales
were $10&nbsp;million and the actual sales for the applicable period were $7&nbsp;million and the
Calculated Price is <B>&#091;***&#093;</B>%, the payment would be equal to $<B>&#091;***&#093;</B>.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>In the event that SUMITOMO elects to convert the exclusive license to
non-exclusive, CONFORMA will provide commercially reasonable support to SUMITOMO or its
designee in their efforts to obtain additional Authorizations in the relevant
geographic area. CONFORMA is not entitled to receive any compensation in relation to
such support.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>5.4.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Sales Outside the Territory</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>CONFORMA and its Affiliates shall not market the Finished Product outside the Territory or
export the Product or the Finished Product to countries outside the Territory and shall
terminate any agreements with any Sublicenses who market the Finished Product outside the
Territory or export the Product or the Finished Product to countries outside the Territory.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>SUMITOMO and its Affiliates shall not market the Finished Product in the Territory or export
the Product or the Finished Product to countries within the Territory and shall terminate
any agreements with any Licensees who market the Finished Product within the Territory or
export the Product or the Finished Product to countries within the Territory.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>5.5.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Labels and Packages</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The package and label of the Product, and advertising and promotional materials for the
Product shall appropriately include relevant Patent information in accordance with the laws
in each country within the Territory and such other information as required by the laws in
each country within the Territory, and shall also indicate for the USA and the Major
European Countries, at SUMITOMO&#146;s request and to the extent the laws and regulations of the
Territory permit, that the Product is manufactured and marketed under a license from
SUMITOMO. Upon the reasonable request of SUMITOMO, CONFORMA shall provide SUMITOMO, free of
charge, with samples of labels, packages, advertising and promotional materials used in the
designated countries in the Territory for information purposes.</TD>
</TR>

</TABLE>
</DIV>
<DIV align="left">
<DIV style="font-size: 3pt; margin-top: 16pt; width: 18%; border-top: 1px solid #000000">&nbsp;</DIV>
</DIV>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
<TR>
    <TD width="3%"></TD>
    <TD width="1%"></TD>
    <TD width="96"></TD>
</TR>

<TR valign="top">
    <TD nowrap align="left"><B>***</B></TD>
    <TD>&nbsp;</TD>
    <TD><B>Confidential Treatment Requested</B></TD>
</TR>

</TABLE>

<P align="right" style="font-size: 10pt"><!-- Folio -->page 12<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">


<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>5.6.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Competing Product</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>During the Initial Period, CONFORMA shall not market, promote or sell any pharmaceutical
product which contains an anthracycline anti-cancer agent as an active ingredient which is
directly competitive in the market (&#147;Competing Product&#148;) in any country within the
Territory.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Notwithstanding the above, in case CONFORMA acquires any Competing Product marketed,
promoted and/or sold in any country within the Territory as a result of merger, acquisition
or transfer of business, then CONFORMA shall divest or license out the right to such
Competing Product to a Third Party within one hundred and eighty (180)&nbsp;days of the
acquisition of such Competing Product.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The failure to comply with the provision in this Section&nbsp;5.6. will give SUMITOMO:</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(i)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>the right to immediately terminate this Agreement without cure period with
respect to the affected country pursuant to Section&nbsp;14.3, upon notice; or</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(ii)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>the right to convert the exclusive license hereof to non-exclusive with respect
to the affected country on prior written notice to CONFORMA.</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>In the event that SUMITOMO elects to exercise the right of the foregoing clause (ii),
CONFORMA will provide reasonable support to SUMITOMO or its designee in their efforts to
obtain additional Authorizations in such country. CONFORMA is not entitled to receive any
compensation in relation to such support.</TD>
</TR>

<TR>
    <TD style="font-size: 12pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><U><B>6.</B></U>&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD> <U><B>SUPPLY OF PRODUCT</B></U></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>6.1.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Supply of Product</B></TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="5%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"><B>6.1.1.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Supply Agreement</B></TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Within six (6)&nbsp;months of the Effective Date the Parties shall enter into a separate document
(&#147;Supply Agreement&#148;) which, unless otherwise agreed by both Parties, restates the terms and
conditions set forth in this Section&nbsp;6. and is supplemented by such other terms and
conditions as are customary in the supply of pharmaceutical products. In the event the
Parties fail to agree on the terms and conditions of the Supply Agreement within such six
(6)&nbsp;month period, the provisions of Section&nbsp;6. shall control.</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="5%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"><B>6.1.2.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Requirements</B></TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>SUMITOMO will supply CONFORMA with the Product to be sold by CONFORMA, its Affiliates and
Sublicensees. CONFORMA shall purchase from SUMITOMO all the Product to be sold by
CONFORMA, its Affiliates and Sublicensees in the countries during the Initial Period.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>In the event that CONFORMA desires to purchase the Product from Third Parties or to
manufacture the Product itself for use by CONFORMA, its Affiliates or Sublicensees in
countries where the Initial Period has expired, CONFORMA shall provide SUMITOMO with two (2)
years&#146; prior notice thereof.</TD>
</TR>

</TABLE>
</DIV>
<P align="right" style="font-size: 10pt"><!-- Folio -->page 13<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV style="margin-top: 6pt"><TABLE width="100%" bordER="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">



</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" bordER="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="7%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"><B>6.1.3.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Specifications</B></TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" bordER="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="5%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>All of the Product supplied by SUMITOMO shall conform to the Specifications and cGMP of the
USA. With respect to the GMP of other relevant countries, CONFORMA shall inform SUMITOMO of
the specific requirements thereof in writing in a timely manner if such requirements are
different from cGMP of the USA. SUMITOMO shall use its Commercially Reasonable Efforts to
satisfy such special requirements.</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" bordER="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="7%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"><B>6.1.4.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Delivery</B></TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" bordER="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="5%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>All the Product shall be delivered to CONFORMA FCA (Incoterms 2000) at Kansai International
Airport, Japan.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>6.2.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Payment</B></TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" bordER="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="7%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"><B>6.2.1.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Purchase Price during the Initial Period</B></TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" bordER="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="5%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The price for the Product shall be calculated semiannually based on Net Sales of the Product
for each of the first six months and second six months of each calendar year (the
&#147;Semiannual Periods&#148;) with respect to the Product to be sold in the countries during the
Initial Period in the following manner:</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="5%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The price at which the Product should be sold by SUMITOMO to CONFORMA, its Affiliates or
Sublicensees (the &#147;Purchase Price&#148;) shall be the higher of the following:</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"></TD>
    <TD width="1%">&nbsp;</TD>
    <TD>(i) The amount resulting from the application of the following formula (the &#147;Calculated
Price&#148;):</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" bordER="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="7%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>(A &#215; B) &#247; C</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="6%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Where:</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="6%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">A = &nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD> Net Sales during the relevant Semiannual Period;</TD>
</TR>
<TR><TD>&nbsp;</TD></TR>

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="6%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"></TD>
    <TD width="1%">&nbsp;</TD>
    <TD>B = &nbsp; <B>&#091;***&#093; </B>(<B>&#091;***&#093;</B>%) until the end of the month
of the second (2nd) anniversary of the first Launch in the Territory, and
thereafter, <B>&#091;***&#093; </B>(<B>&#091;***&#093;</B>%);</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="6%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"></TD>
    <TD width="1%">&nbsp;</TD>
    <TD>C = &nbsp; the number of fifty (50)&nbsp;mg vials of the Product actually
sold by CONFORMA, its Affiliates or Sublicensees during the relevant Semiannual
Period;</TD>

</TR><TR><TD>&nbsp;</TD></TR>

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="6%" nowrap align="left">&nbsp;</TD>
    <TD>or</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>&nbsp;</TD>
</TR>

<TR><TD>&nbsp;</TD></TR>
<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="6%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(ii)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>&#091;***&#093; </B>per fifty (50)&nbsp;mg unlabeled vial (the &#147;Minimum Price&#148;).</TD>
</TR>
<TR><TD>&nbsp;</TD></TR>

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="6%" nowrap align="left">&nbsp;</TD>
    <TD width="3%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The Purchase Price will include the manufacturing cost of the Product and running royalties
for the licenses for Patents, Know-how and Trademarks granted with respect thereto under
this Agreement.</TD>
</TR>
<TR><TD>&nbsp;</TD></TR>

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="7%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"><B>6.2.2.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Payments Procedure</B></TD>
</TR>

</TABLE>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 7%">(i)&nbsp;SUMITOMO shall invoice CONFORMA in US Dollars (&#147;USD&#148;) only after a shipment of the
Product is available under FCA as set forth in Section&nbsp;6.1.4 above. Payment for each
shipment shall be made within two (2)&nbsp;months from the date of invoice and as directed by
SUMITOMO.<BR>
</DIV>

<DIV align="left">
<DIV style="font-size: 3pt; margin-top: 16pt; width: 18%; border-top: 1px solid #000000">&nbsp;</DIV>
</DIV>

<TABLE width="100%" bordER="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
<TR>
    <TD width="3%"></TD>
    <TD width="1%"></TD>
    <TD width="96"></TD>
</TR>

<TR valign="top">
    <TD nowrap align="left"><B>***</B></TD>
    <TD>&nbsp;</TD>
    <TD><B>Confidential Treatment Requested</B></TD>
</TR>

</TABLE>

<P align="right" style="font-size: 10pt"><!-- Folio -->page 14<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 2%">(ii)&nbsp;At each shipment, SUMITOMO shall issue the invoice based on the Minimum Price
calculated in USD at the average of Telegraphic Transfer Middle (TTM)&nbsp;rate published by the
Bank of Tokyo Mitsubishi on the last banking day of the month proceeding the month of
shipment.
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 2%">(iii)&nbsp;Within two (2)&nbsp;months of the end of each Semiannual Period CONFORMA shall calculate
the Net Sales and the Calculated Price of the said Semiannual Period in USD. With respect
to sales of any Finished Products invoiced in a currency other than USD, the Net Sales
hereunder shall be converted from local currency to USD by CONFORMA and such exchange shall
be determined based on the USD equivalent exchange rate as reported in the Unites States
Federal Reserve Statistical Release: Foreign Exchange Rates (Annual), available on-line at
http://www.federalreserve.gov/releases/ for said calendar year.
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 2%">(iv)&nbsp;CONFORMA shall provide SUMITOMO with a financial report showing the Net Sales and
Calculated Price within two (2)&nbsp;months of the end of each Semiannual Period.
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 2%">(v)&nbsp;If the Calculated Price in the relevant Semiannual Period calculated in accordance with
the foregoing is higher than the Minimum Price by CONFORMA, CONFORMA shall pay the
difference as running royalties for the rights granted hereunder by the end of third month
following the end of said Semiannual Period with the financial report for such Semiannual
Period including the information of annual sales volume, Net Sales, Calculated Price and
amount of running royalties with the exchange rate applied.
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 2%">(vi)&nbsp;The Parties shall treat such financial reports and information as confidential under
Section&nbsp;13 of this Agreement and shall cause their respective accounting firms to retain all
such financial reports and information in confidence.
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 2%"><B>6.2.3. Adjustments to Purchase Price After the Initial Period</B>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 2%">With respect to the Product to be sold in the countries where the Initial Period has
expired, SUMITOMO will continue the supply of the Product to CONFORMA under the conditions
of clause (i)&nbsp;below unless CONFORMA elects to pursue the option under clause (ii)&nbsp;below.
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 2%">(i)&nbsp;If CONFORMA, its Affiliates or Sublicensees wish to continue to purchase the Product
from SUMITOMO, the Purchase Price shall be adjusted to the higher of (a)&nbsp;the price defined
as <B>&#091;***&#093; </B>percent ( <B>&#091;***&#093; </B>%) of the Net Sales divided by the number of
fifty (50)&nbsp;mg vials of the Product actually sold by CONFORMA, its Affiliates or Sublicensees
or (b)&nbsp;the new Minimum Price that the Parties will discuss in good faith and agree to. In
the event the Parties fail to agree upon the new Minimum Price, the Minimum Price shall
remain <B>&#091;***&#093; </B>per fifty (50)&nbsp;mg unlabeled vial.
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 2%">(ii)&nbsp;If CONFORMA, its Affiliates or Sublicensees decide to purchase the Product from a Third
Party or manufacture the Product by itself, upon the request of CONFORMA and the provision
to SUMITOMO of two (2)&nbsp;years&#146; notice pursuant to Section&nbsp;6.1.2, SUMITOMO will license to
CONFORMA, its Affiliates or its Sublicensees the Know-how and Manufacturing Technology which
is necessary or useful for manufacturing the Compound and Product. In such event, as
consideration of such license, CONFORMA shall pay to SUMITOMO <B>&#091;***&#093; </B>percent
( <B>&#091;***&#093; </B>%) of the Net Sales of the Finished Product manufactured by CONFORMA, its
Affiliates or its Sublicensees until the twenty fifth (25th) anniversary of the date of the
first Launch.
</DIV>
 <DIV align="left">
<DIV style="font-size: 3pt; margin-top: 16pt; width: 18%; border-top: 1px solid #000000">&nbsp;</DIV>
</DIV>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
<TR>
    <TD width="3%"></TD>
    <TD width="1%"></TD>
    <TD width="96"></TD>
</TR>

<TR valign="top">
    <TD nowrap align="left"><B>***</B></TD>
    <TD>&nbsp;</TD>
    <TD><B>Confidential Treatment Requested</B></TD>
</TR>

</TABLE>

<P align="right" style="font-size: 10pt"><!-- Folio -->page 15<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 4%">(iii)&nbsp;SUMITOMO may decide after ten (10)&nbsp;years from the first Launch of CONFORMA to
discontinue manufacturing the Product with two (2)&nbsp;years prior notice to CONFORMA. In such
event, SUMITOMO shall (A)&nbsp;grant to CONFORMA, its Affiliate or its Sublicensee a royalty-free
license for the Know-how and Manufacturing Technology which is necessary or useful for
manufacturing the Compound and Product; (B)&nbsp;provide CONFORMA, its Affiliate or its
Sublicensee with any technical data incorporated in the Know-How, and SUMITOMO shall
promptly provide related documentation; and (C)&nbsp;assist CONFORMA, its Affiliate or its
Sublicensee with the working up and use of the Know-How and Manufacturing Technology and
with the training of personnel to the extent which may reasonably be necessary in relation
to the manufacture of the Product by CONFORMA, its Affiliate or its Sublicensee.
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 4%"><B>6.2.4. Adjustment related to Combination Product</B>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 4%">Notwithstanding the other provisions of this Section&nbsp;6.2.4, with respect to any Combination
Product, the Parties shall meet approximately one (1)&nbsp;year prior to the anticipated first
Launch of such Combination Product to negotiate in good faith and agree to the Minimum Price
applied to such Combination Product, as well as an appropriate adjustment to Net Sales which
will be calculated as a fraction determined as follows:
</DIV>
<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
<!-- Begin Table Head -->
<TR valign="bottom">
    <TD width="48%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="4%">&nbsp;</TD>
    <TD width="2%">&nbsp;</TD>
    <TD width="44%">&nbsp;</TD>
</TR>
<!-- End Table Head -->
<!-- Begin Table Body -->
<TR valign="bottom">
    <TD align="right" rowspan="3" valign="middle"><DIV style="margin-left:0px; text-indent:-0px">Net Sales of the Combination Product&nbsp;&nbsp;x
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">A
</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR style="font-size: 1px">
    <TD>&nbsp;</TD>
    <TD align="left" valign="top" style="border-top: 1px solid #000000">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD>&nbsp;</TD>
    <TD align="center" valign="top">A&#043;B</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>



<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 4%">Where &#147;A&#148; above represents the standard sales price of the Finished Product, containing the
same amount of the Compound as the sole active ingredient as the Combination Product in
question, in the given country and &#147;B&#148; above represents the standard sales price of the
ready-for-sale form of a product containing the same amount of the other active
pharmaceutical ingredient(s) that is contained in the Combination Product in question in the
given country. If such products are not sold separately, the Parties shall use good faith
efforts to agree on an appropriate mechanism for adjustment of the Net Sales for such
Combination Product. In the event the parties fail to agree on the Minimum Price to be
applied to such Combination Product or the mechanism for adjustment of such Net Sales, the
Minimum Price shall remain <B>&#091;***&#093; </B>per fifty (50)&nbsp;mg unlabeled vial.
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>6.3.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Forecast and Order</B></TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="5%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"><B>6.3.1.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Supply Forecast</B></TD>
</TR>

</TABLE>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 5%">(i)&nbsp;Eighteen (18)&nbsp;months prior to the expected first delivery date of Product for the first
Launch in the Territory, the Parties shall discuss the projected quantity requirements for
the Product for the first three (3)&nbsp;years following the first Launch in the Territory.<BR>
</DIV>
 <DIV align="left">
<DIV style="font-size: 3pt; margin-top: 16pt; width: 18%; border-top: 1px solid #000000">&nbsp;</DIV>
</DIV>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
<TR>
    <TD width="3%"></TD>
    <TD width="1%"></TD>
    <TD width="96"></TD>
</TR>

<TR valign="top">
    <TD nowrap align="left"><B>***</B></TD>
    <TD>&nbsp;</TD>
    <TD><B>Confidential Treatment Requested</B></TD>
</TR>

</TABLE>

<P align="right" style="font-size: 10pt"><!-- Folio -->page 16<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 2%">(ii)&nbsp;Twelve (12)&nbsp;months prior to the beginning of the calendar quarter which contains the
expected date of the first Launch in the Territory, CONFORMA shall provide SUMITOMO with a
good faith forecast of projected quantity requirements for the Product for the forthcoming
three (3)&nbsp;years beginning with the calendar quarter six (6)&nbsp;months after the delivery of
such forecast, including the quarterly quantities of the Product for the first year and the
yearly quantities of the Product for the subsequent two years. The first quarter of the
forecast shall be deemed as a firm order. CONFORMA shall designate a delivery date within
the applicable calendar quarter at the time the forecast becomes a firm order. CONFORMA
shall update such forecast for the three (3)&nbsp;year period on a rolling basis by the end of
every calendar quarter thereafter during the term of this Agreement and the forecast for
each first calendar quarter shall become a firm order on a rolling basis.
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 2%"><B>6.3.2. Firm Order</B>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 2%">The quantity of the Product in the firm order shall not be less than seventy five percent
(75%) nor more than one hundred and twenty five percent (125%) of the quantity specified in
the latest forecast for the same quarter. In case the quantity in the firm order exceeds
one hundred and twenty five percent (125%) of that in the latest forecast, SUMITOMO&#146;s
failure to supply the quantities exceeding one hundred and twenty five percent (125%) of
that in the latest forecast shall not constitute a breach of this Agreement.
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 2%"><B>6.3.3. Quantity</B>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 2%">The minimum order quantity (lot)&nbsp;per shipment shall not be less than the actual batch size
of 8000 vials.
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 2%"><B>6.3.4. Quality Assurance Tests</B>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 2%">CONFORMA shall be responsible for (i)&nbsp;performing quality assurance testing of all Products
in accordance with the Specifications and (ii)&nbsp;notifying SUMITOMO of the result, within
forty (40)&nbsp;days after receipt at CONFORMA&#146;s facilities of each shipment of the Product. On
CONFORMA&#146;s failure to reject any Product within forty five (45)&nbsp;days of receipt, CONFORMA
shall be deemed to have accepted such Product. In the event that the tests performed by
CONFORMA indicate that a shipment of Product does not meet the Specifications, SUMITOMO
shall as soon as is commercially reasonable replace the quantity of the Product affected.
In such event, SUMITOMO shall be offered an opportunity to re-test such Product and if tests
performed by CONFORMA and SUMITOMO reach inconsistent results, the Parties agree to have the
Product tested by a reputable Third Party testing organization selected jointly by the
Parties and to cooperate in the furnishing of necessary analytical methodology, subject to
appropriate safeguards of confidentiality, to such testing organization. The decision of
such Third Party organization shall be binding upon both Parties and the Party whose test
results led to the false conclusion with respect to the Product meeting, or failing to meet,
Specifications shall bear the costs of such analysis and of the replacement shipment of
Product, if any; provided that if CONFORMA&#146;s test results led to a false conclusion, the
initial shipment of Product shall be sent to CONFORMA.
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 2%"><B>6.3.5. Retention of Samples</B>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 2%">SUMITOMO shall retain samples from each lot of the Product in quantities sufficient for
complete analysis and manufacturing batch records of each lot of the Product, until the
first (1st) anniversary of the expiration of the shelf life of such lot.
</DIV>

<P align="right" style="font-size: 10pt"><!-- Folio -->page 17<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 4%"><B>6.3.6. Labeling and Packaging</B>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 4%">CONFORMA shall label and package the Product for the Territory at a facility to be
determined by CONFORMA, in its sole discretion in conformity with all the laws and
regulations including GMP of the relevant countries in the Territory.
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 4%"><B>6.3.7. Backup/Complementary Source for the Manufacture of Compound or Product</B>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 4%">SUMITOMO shall maintain a reasonable amount of safety stock for the Product and the Compound
and/or the main stable intermediate in a quantity to be agreed to by CONFORMA and SUMITOMO
no later than eighteen (18)&nbsp;months prior to the expected first delivery date of Product for
the first Launch in the Territory. In case of necessity, SUMITOMO and CONFORMA will discuss
the backup /complementary source.
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>6.4.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Termination</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>In the event the Supply Agreement is executed, the Supply Agreement shall automatically
terminate in the event of the early termination of this Agreement for any reason. Upon the
expiration of this Agreement, the Supply Agreement will continue in effect, but each Party
may terminate the Supply Agreement upon two (2)&nbsp;years&#146; notice, which notice may be delivered
up to two (2)&nbsp;years prior to the expiration date of this Agreement.</TD>
</TR>

<TR>
    <TD style="font-size: 12pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><U><B>7.</B></U>&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD> <U><B>TRADEMARK</B></U></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>7.1.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Grant of Right</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>&#147;Calsed&#148; is the first candidate of the Trademark in the Territory but Parties shall discuss
and agree on the selection of the Trademark if Calsed is not available or not suitable as a
Trademark in the Territory. However, in the event of disagreement between Parties, CONFORMA
has the final decision-making right. Then, SUMITOMO shall file, prosecute and maintain the
Trademark at its own cost in each country within the Territory in which CONFORMA shall
market the Finished Product.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>7.2.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Ownership</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>SUMITOMO shall own the Trademark.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>7.3.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Filing, Prosecution and Maintenance</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>SUMITOMO shall diligently prosecute and maintain the Trademark at its sole cost and expense
and shall keep CONFORMA reasonably advised as to the status of the maintenance of the
Trademark and any clearance, applications and registrations for any substitute Trademarks.
SUMITOMO will consult with CONFORMA in a timely manner, as it relates to the Territory,
concerning:</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(i)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>scope and content of any application or amendment in connection with the
Trademark prior to filing such application or amendment</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(ii)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>content of any proposed responses to official actions in connection with the
Trademark.</TD>
</TR>

</TABLE>
</DIV>
<P align="right" style="font-size: 10pt"><!-- Folio -->page 18<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>



<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">



</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" bordER="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>If SUMITOMO fails to timely file for or to maintain a registration for the Trademark
following a request by CONFORMA, or to pay any fee required to maintain the Trademark,
CONFORMA shall have the right, at its expense, to clear, file, prosecute and maintain the
applications and registrations for the Trademark in SUMITOMO&#146;s name and on SUMITOMO&#146;s
behalf.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>7.4.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Royalties for Trademark</B></TD>
</TR>
</table>
</div>


<DIV style="margin-top: 6pt">
<TABLE width="100%" bordER="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%">&nbsp;</TD>
    <TD align="left">(i)&nbsp; Even after the expiration of this Agreement, as far as CONFORMA purchases the Product
from SUMITOMO, the license set forth in Section&nbsp;2.1(c) shall remain in full force and effect
and the royalties for such license are included in the Purchase Price as defined in Section
6 or the Supply Agreement.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%">&nbsp;</TD>
    <TD align="left">(ii)&nbsp; In case CONFORMA purchases the Product from a supplier other than SUMITOMO, or CONFORMA
manufactures the Product by itself, and CONFORMA wishes to continue to use the Trademark in
the Territory, the license set forth in Section&nbsp;2.1(c) shall remain in full force and effect
and CONFORMA shall pay to SUMITOMO royalties for such license at a rate of <B>&#091;***&#093; </B>percent
(<B>&#091;***&#093;</B>%) of Net Sales in relevant countries, on a country-per-country basis until the twenty
fifth (25<SUP style="font-size: 85%; vertical-align: text-top">th</SUP>) anniversary of the date of the first Launch of the Finished Product.
Payment for above royalties shall be made within ninety (90)&nbsp;days from the date from the
end of calendar year and be accompanied by the financial report as described in Section&nbsp;6 or
the Supply Agreement.</TD>
</TR>


</table>
</div>

<DIV style="margin-top: 6pt">
<TABLE width="100%" bordER="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>7.5.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Infringement by Third Party</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Each Party shall notify the other promptly upon learning of any actual, alleged, or
threatened infringement of the Trademark applicable to a Product or of any unfair trade
practices, trade dress imitation, passing off of counterfeit goods, or like offenses. Upon
learning of such offense, CONFORMA shall have the first right to respond to and defend any
such infringement or offense. In the event CONFORMA elects to do so, SUMITOMO will
cooperate with and provide assistance and authority to CONFORMA, provided that such
assistance is economically reasonable. In the event that CONFORMA elects, within ninety (90)
days of notification thereof, not to respond to or defend any such infringement or offense
or abandons such defense, then, in such event, SUMITOMO shall have the option to do so,
provided that CONFORMA will cooperate with and provide assistance to SUMITOMO, and provided
that such assistance is economically reasonable.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The Party bringing the foregoing action shall do so at its own cost and expense. The Party
not bringing such action agrees to join in such action as a plaintiff if necessary to
prosecute the action. Any damages or other monetary awards recovered from settlement or
judgment from such an action shall be allocated first to reimburse the costs and expenses of
the Party bringing the action, then to reimburse the costs and expenses, if any, of the
other Party (except for costs associated with the other Party being represented by counsel
of its own choice). Any amounts remaining shall be deemed as the Net Sales and the Parties
shall agree on an appropriate royalty rate to adequately share such incremental Net Sales
reflecting the principles set forth in Section&nbsp;7.4.</TD>
</TR>

</TABLE>
</DIV>
<DIV align="left">
<DIV style="font-size: 3pt; margin-top: 16pt; width: 18%; border-top: 1px solid #000000">&nbsp;</DIV>
</DIV>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
<TR>
    <TD width="3%"></TD>
    <TD width="1%"></TD>
    <TD width="96"></TD>
</TR>

<TR valign="top">
    <TD nowrap align="left"><B>***</B></TD>
    <TD>&nbsp;</TD>
    <TD><B>Confidential Treatment Requested</B></TD>
</TR>

</TABLE>

<P align="right" style="font-size: 10pt"><!-- Folio -->page 19<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">


<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><U><B>8.</B></U>&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD> <U><B>REGULATORY AFFAIRS AND INSPECTIONS</B></U></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>8.1.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Acquisition and Maintenance of Authorization</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>CONFORMA shall have the sole responsibility for preparing and filing the INDs and the NDA
for the Product with the Regulatory Authority in the countries where CONFORMA has an
intention to market the Finished Product. CONFORMA shall immediately notify SUMITOMO of the
submission of any IND and NDA for the Product and of the grant of any Authorization.
CONFORMA shall be responsible for applying for and obtaining any extensions of the Data
Protection period in countries where CONFORMA markets the Product.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>CONFORMA shall use Commercially Reasonable Efforts to make regulatory filings in the
countries where CONFORMA has an intention to market the Finished Product, contingent on
SUMITOMO fulfilling its obligations under Sections&nbsp;4.1(i) and 4.1(iii) of this Agreement and
supply obligations under Section&nbsp;6 or the Supply Agreement.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>CONFORMA shall be solely responsible for any actions, including but not limited to clinical
trials after obtaining the Authorization, at its expense to maintain each
Authorization in the countries where CONFORMA markets the Product.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>CONFORMA shall be responsible for all interactions with Regulatory Authorities in the
Territory. Authorization shall be held by CONFORMA in CONFORMA&#146;s name in the Territory.
CONFORMA will have the sole responsibility for applying for, obtaining and maintaining
Authorization in the Territory. All expenses necessary for applying for, obtaining and
maintaining Authorization in the Territory shall be borne by CONFORMA. At CONFORMA&#146;s
request, SUMITOMO shall cooperate in the preparation and maintenance of all regulatory
filings for the Finished Product filed by CONFORMA, including, without limitation, preparing
sections of regulatory filings that are applicable to the manufacturing activities of
SUMITOMO or to preclinical, clinical and commercial data generated by SUMITOMO.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>8.2.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Maintenance of Data</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>SUMITOMO shall keep and maintain all the reports, data and raw data which SUMITOMO provides
to CONFORMA and which constitute parts of or basis of the NDA for the Product submitted by
CONFORMA for the period which the laws and regulations of the countries where CONFORMA
markets or intends to market the Product require. In order to ensure the foregoing,
CONFORMA shall inform SUMITOMO of such period. If there are any Affiliates or Third Party
which produced all or parts of the foregoing reports, data, and raw data for SUMITOMO,
SUMITOMO shall have such Affiliate or seek to have such Third Party comply with the
foregoing obligation of maintenance.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>In the event that SUMITOMO notifies CONFORMA of its intent to use the reports, data and raw
data obtained by CONFORMA for the purpose of the NDA for the Product outside the Territory,
CONFORMA shall keep and maintain all such reports, data and raw data for the period which
the laws and regulations of the each country outside the Territory requires. In order to
ensure the foregoing, SUMITOMO shall inform CONFORMA of such period of each county outside
the Territory. If there is any Affiliate or Third Party which produces all or parts of the
foregoing reports, data, and raw data for CONFORMA, CONFORMA shall have such Affiliate or
seek to have such Third Parties comply with the foregoing obligation of maintenance.</TD>
</TR>

</TABLE>
</DIV>
<P align="right" style="font-size: 10pt"><!-- Folio -->page 20<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">


<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>8.3.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Inspections by Regulatory Authority</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>SUMITOMO shall accept, have its Affiliate accept, and seek to have the Third Parties who
cooperate with or assist SUMITOMO regarding the development or manufacture of the Product
outside the Territory, if any, to accept, the inspection by the Regulatory Authority if it
is required for CONFORMA to obtain or maintain the Authorization. CONFORMA will use
Commercially Reasonable Efforts to obtain the information of such inspection in advance and
forward it to SUMITOMO. SUMITOMO shall permit CONFORMA or its Affiliates to be present at
any inspection by Regulatory Authorities and shall provide advance notice of any such
inspection.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>In the event that SUMITOMO uses the reports, data and raw data obtained by CONFORMA for the
purpose of the NDA for the Product outside the Territory, CONFORMA shall accept, have its
Affiliate accept, and seek to have the Third Parties who cooperate with or assist CONFORMA
regarding the Development, if any, to accept, the inspection by the regulatory authorities
of the countries outside the Territory if it is required to obtain or maintain the marketing
authorization for the Product in such country. SUMITOMO shall use Commercially Reasonable
Efforts to obtain the information of such inspection in advance and forward it to CONFORMA.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>In case of requests from Regulatory Authorities regarding specific historical reports, the
Parties agree to reasonably collaborate to meet those requests.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>8.4.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Inspections by Parties</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>CONFORMA may inspect SUMITOMO&#146;s or its Affiliate&#146;s facilities during each entity&#146;s normal
business hours upon reasonable prior notice and SUMITOMO shall accept or shall have its
Affiliate accept such inspection to the extent such facilities relate to the manufacture of
the Compound or the Product or the maintenance of the reports, data and raw data referred to
in Section&nbsp;8.2.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>SUMITOMO may inspect CONFORMA&#146;s or its Affiliate&#146;s facilities during each entity&#146;s normal
business hours upon reasonable prior notice and CONFORMA shall accept or shall have its
Affiliate accept such inspection to the extent such facilities relate to the Development,
manufacture, or distribution of the Product in the Territory.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Each Party shall use Commercially Reasonable Efforts to have the Third Parties who are
entrusted or contracted out to a part of each Party&#146;s responsibility under this Agreement,
if any, to accept the foregoing inspections by the other Party.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>8.5.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Pharmacovigilance / Drug Safety Matters</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The Parties agree to inform each other about adverse events occurring or having occurred in
connection with the use of the Compound or the Product which comes into its knowledge. The
Parties agree to handle data and information about adverse events occurring or having
occurred in connection with the use of the Compound or the Product according to the
respective ICH-Guidelines, FDA requirements, requirements of the relevant European
registration authorities, requirements of the Regulatory Authority and/or requirements of
any other relevant regulatory authority.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The Parties shall execute a separate agreement specifying the procedure for the information
exchange of the adverse drug reactions which may occur during the Development no later than
the Initiation by CONFORMA of the first clinical trial of the Product in the Territory
(&#147;Clinical Pharmacovigilance Agreement&#148;).</TD>
</TR>

</TABLE>
</DIV>
<P align="right" style="font-size: 10pt"><!-- Folio -->page 21<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">


<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>After completion of the last clinical trial for the NDA for the first country in which an
NDA is to be made but no later than the expected date when CONFORMA obtains the first
Authorization in the Territory, the Parties shall execute another agreement which includes
handling of post marketing studies and spontaneous or literature reports, surveillance, etc.
in relation to Compound, Product, and Finished Product in the Territory by CONFORMA, its
Affiliates or its Sublicensees, and outside Territory by SUMITOMO, its Affiliates or its
Licensees, specifying the procedure for the information exchange of the adverse events which
may occur after the Launch (&#147;Post Marketing Pharmacovigilance Agreement&#148;).</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>SUMITOMO shall be solely responsible for reporting adverse events to the regulatory
authorities outside the Territory. CONFORMA, as the Party owning the IND, NDA or
Authorization, shall be solely responsible for reporting adverse drug experiences to the
Regulatory Authorities in the respective territories.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The Parties will maintain a safety database for the Product, that allows them to manage
safety data collected and fulfill their regulatory requirements in their respective
Territory.</TD>
</TR>

<TR>
    <TD style="font-size: 12pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><U><B>9.</B></U>&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD> <U><B>PATENTS and Updated Technology</B></U></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>9.1.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Updated Technology</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>During the term of this Agreement, SUMITOMO shall advise CONFORMA as soon as commercially
reasonable of any improvements or inventions concerning the Compound and/or the Product or
its use made by either SUMITOMO or any of its Affiliates, Licensees or Third Parties
contracted by SUMITOMO, as well as status of each Patent and acquisition of new Patent. The
foregoing improvements or inventions constitute parts of the rights granted to CONFORMA
under Section&nbsp;2.1, except for those rights which SUMITOMO has acquired or obtained pursuant
to a license from a Third Party which is subject to the payment of consideration by
SUMITOMO, in which case SUMITOMO shall only be obliged to grant a license to such
improvements or inventions to CONFORMA to the extent permitted by the arrangement with such
Third Party and the grant of such license to CONFORMA shall be subject to the payment of
reasonable additional compensation by CONFORMA, provided that SUMITOMO shall use its
Commercially Reasonable Efforts to obtain from such Third Party the right to license such
improvements or inventions to CONFORMA, and use its Commercially Reasonable Efforts to
mitigate the consideration thereof. With respect to an additional compensation for such
improvements or inventions, the Parties shall negotiate in good faith a reasonable
compensation for license grant to CONFORMA.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>9.2.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Rights to Improvements</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>As between SUMITOMO and CONFORMA, CONFORMA or its Affiliates own all right, title and
interest in and to all the Improvements, subject to the SUMITOMO&#146;s right to the Improvements
as set forth in Section&nbsp;2.3. CONFORMA or its Affiliates have the right to file a patent in
the Territory and outside the Territory related to such Improvements.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>During the term of this Agreement, CONFORMA shall inform SUMITOMO as soon as commercially
reasonable of any patent applications covering an Improvement.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>9.3.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Application and Maintenance of Patents</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>SUMITOMO shall, subject to the provisions of Section&nbsp;9.4, at its cost, be responsible for
diligently preparing, filing, maintaining, and renewing the Patents in the Territory.</TD>
</TR>

</TABLE>
</DIV>
<P align="right" style="font-size: 10pt"><!-- Folio -->page 22<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">
<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>



<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">


<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>SUMITOMO shall be responsible for applying for and obtaining any patent term extensions,
including supplementary protection certificate; provided, however, that should SUMITOMO
decide not apply for, continue to prosecute or maintain a Patent in the Territory because
SUMITOMO reasonably believes that such Patent can no longer provide exclusivity protection
for the Compound or Product in the Territory, SUMITOMO shall so notify CONFORMA and then
CONFORMA may take over the prosecution and/or maintenance of the Patent from SUMITOMO at its
own cost.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>9.4.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>No Warranty</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>SUMITOMO will use Commercially Reasonable Efforts to obtain the grant of the Patents by the
governmental patent office in each country in the Territory where SUMITOMO elects to apply
for Patents, but gives no warranty that Patents will be granted or upheld in such country or
in any other country within the Territory. CONFORMA acknowledges that the rights granted
hereunder may not provide market exclusivity in the Territory and that SUMITOMO makes no
representations or warranties regarding the existence of market exclusivity. Even if no
patent protection is obtained in the Territory, it shall not provide a basis for
termination, rescission or cancellation of this Agreement, nor shall it entitle any Party to
demand a revision or renegotiation of this Agreement or any of its provisions.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>9.5.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Infringement by Third Party</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Each Party shall promptly notify the other of any infringement of the Patents or threat of
such infringement by a Third Party in the Territory which the Party comes to know. In the
event of the foregoing infringement or threat, SUMITOMO will, at SUMITOMO&#146;s option and at
its sole cost and expense, commence appropriate legal action to stop or prevent such
infringement. Only SUMITOMO has the right to engage in any legal action and, once engaged,
has the sole right to pursue such action, in its complete and sole discretion, provided that
SUMITOMO shall refer to the suggestions or opinions of CONFORMA. CONFORMA shall provide
SUMITOMO, upon the request of SUMITOMO and at the cost of SUMITOMO, with support which is
necessary for SUMITOMO to show the infringement or the damage in the action, provided that
such support is economically reasonable.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Within sixty (60)&nbsp;days after receiving or giving above notice, SUMITOMO shall notify
CONFORMA of whether SUMITOMO commence legal action to stop or prevent the infringement. If
SUMITOMO decides not to commence legal action or fails to initiate such action within thirty
(30)&nbsp;days after giving a notice to CONFORMA of its decision of commencement of legal action,
CONFORMA has the right, but not the obligation to begin action at CONFORMA&#146;s option and at
CONFORMA&#146;s sole cost and expense. In such event, SUMITOMO shall provide CONFORMA, at the
cost of CONFORMA, with support which is necessary for CONFORMA to initiate and maintain the
action, provided that such support is economically reasonable.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Notwithstanding the foregoing paragraph, in the event that the Third Party asserts, as a
defense or as a counterclaim that the Patent is invalid or unenforceable, then each Party
shall promptly notify the other Party. SUMITOMO shall have the first right, but not the
obligation, to respond to such defense or defend against such counterclaim, provided that no
settlement or consent judgment or other voluntary final disposition may be entered into
without the consent of CONFORMA if such settlement would effect CONFORMA&#146;s rights under this
Agreement.<BR></TD>
</TR>

</TABLE>
</DIV>
<P align="right" style="font-size: 10pt"><!-- Folio -->page 23<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">


<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Neither Party shall settle such action without the consent of the other Party, such consent
not to be unreasonably withheld, conditioned or delayed. Any resulting award, judgment or
settlement amount in favor of SUMITOMO or CONFORMA in the action under this Section&nbsp;9.5.
shall be first allocated to cover the cost and expenses, including reasonable attorney&#146;s
fees, which each Party has spent for the action, and shall be split <B>&#091;***&#093; </B>percent
( <B>&#091;***&#093; </B>%) to CONFORMA and <B>&#091;***&#093; <br></B>percent ( <B>&#091;***&#093; </B>%) to SUMITOMO.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>9.6.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Infringement Alleged by Third Party</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>If any Third Party claims or alleges that CONFORMA, its Affiliates, or Sublicensee infringes
such Third Party&#146;s patent or other intellectual property by manufacturing, importing, using,
marketing, promoting, distributing or selling the Product in the Territory, CONFORMA has the
right, but not the obligation to defend against such Third Party at its sole cost and
expense. However, if CONFORMA needs the technical information of SUMITOMO to defend against
such Third Party which CONFORMA does not have, SUMITOMO shall provide it to CONFORMA.
CONFORMA agrees to use the technical information provided by SUMITOMO under this Section
9.6. only for the purpose of defending against the Third Party alleging the infringement.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Notwithstanding the foregoing paragraph, in the event that the Third Party asserts in a
claim that the Patent is invalid or unenforceable, then CONFORMA shall promptly notify
SUMITOMO. SUMITOMO shall have the first right, but not the obligation, to respond to such
claim provided that no settlement or consent judgment or other voluntary final disposition
may be entered into without the consent of CONFORMA if such settlement would effect
CONFORMA&#146;s rights under this Agreement, provided however, that CONFORMA shall not withhold
such consent unreasonably.</TD>
</TR>

<TR>
    <TD style="font-size: 12pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><U><B>10.</B></U>&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD> <U><B>RECORDS</B></U></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>10.1.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Records</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>CONFORMA shall maintain and retain all records relating to sales, sales contracts, invoices,
accounts, medical enquiries and other transactions directly related to the Product that may
be necessary for the purpose of calculating, Net Sales under this Agreement for a period of
not less than five (5)&nbsp;years from the date on which such records arose.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>10.2.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Examination by Certified Public Accountant</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>SUMITOMO has the right to have independent certified public accountant selected by and
retained at the expense of SUMITOMO with approval of CONFORMA, which shall not be
unreasonably withheld, examine during normal working hours of CONFORMA and at a date
previously agreed upon with CONFORMA the books and records kept by CONFORMA and its
Affiliate to the extent necessary to verify the accuracy of the Finished Product sales or
payments made in this Agreement, if any, reports presented and payments made to SUMITOMO
hereunder. Such examination shall not be more often than once per calendar year and for not
more than two (2)&nbsp;previous years. Any deviations shall either be credited or paid by the
other Party, as the case may be. CONFORMA shall ensure that corresponding provisions are
contained in the sublicense agreements with Third Parties. SUMITOMO agrees that the report
of above examination by certified public accountant to SUMITOMO shall be limited to the
information relevant to verification of the accuracy of Product sales or payments in this
Agreement, if any, reports presented and payments made to SUMITOMO hereunder.<BR></TD>
</TR>

</TABLE>
</DIV>
<DIV align="left">
<DIV style="font-size: 3pt; margin-top: 16pt; width: 18%; border-top: 1px solid #000000">&nbsp;</DIV>
</DIV>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
<TR>
    <TD width="3%"></TD>
    <TD width="1%"></TD>
    <TD width="96"></TD>
</TR>

<TR valign="top">
    <TD nowrap align="left"><B>***</B></TD>
    <TD>&nbsp;</TD>
    <TD><B>Confidential Treatment Requested</B></TD>
</TR>

</TABLE>

<P align="right" style="font-size: 10pt"><!-- Folio -->page 24<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>


<DIV style="font-family: Helvetica,Arial,sans-serif">
<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>



<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">


<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><U><B>11.</B></U>&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD> <U><B>TAXATION</B></U></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>11.1.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Responsibility for Tax</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Subject to Section&nbsp;11.2 below, CONFORMA is solely responsible for the payment of any and all
taxes arising from the existence or operation of its business or from the performance of its
obligations hereunder including, without limitation, income taxes, withholding taxes,
employee payroll and social security and welfare taxes which may be imposed upon CONFORMA in
accordance with applicable laws. Likewise, subject to Section&nbsp;11.2 below, SUMITOMO is
solely responsible for the payment of any taxes arising from the existence or operation of
its business, the income and profits resulting therefrom or from the performance of its
obligations hereunder and for any and all obligations which may arise from its employment of
any persons including, without limitation, any personnel of SUMITOMO dedicated to the
manufacturing of the Compound.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>11.2.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Withholding Tax</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>If a withholding tax is imposed on any event payment, payment for the Product, or royalty
hereof is enacted, CONFORMA shall deduct the amount of any such applicable withholding tax
from the amount due to SUMITOMO and pay over such withholding tax deducted to the relevant
taxing authorities. CONFORMA shall not provide any gross-up amount with respect to any
applicable withholding tax. CONFORMA shall provide SUMITOMO with the official receipts and
such other evidence of payment of any such applicable withholding tax as SUMITOMO may
request in writing promptly following such request. SUMITOMO shall provide documentation to
CONFORMA as reasonably requested to minimize withholdings otherwise required by the taxing
authorities. CONFORMA shall render SUMITOMO reasonable assistance in order to allow
SUMITOMO to obtain the benefit of any present and future treaty for the avoidance of double
taxation in force between Japan and the respective countries in the Territory.</TD>
</TR>

<TR>
    <TD style="font-size: 12pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><U><B>12.</B></U>&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD> <U><B>FINANCIAL MATTERS</B></U></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>12.1.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Late Payments</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>In case CONFORMA fails to make each payment required hereof by the due date, SUMITOMO will
charge CONFORMA a penalty at the lower of (i)&nbsp;interest accruing on any such unpaid balance
at the average year-to-date rate London Inter-Bank Offering Rate (LIBOR)&nbsp;in effect from time
to time plus two percent (2 %) per annum or (ii)&nbsp;the highest rate allowable under applicable
law.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>12.2.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Manner of Payment</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>All amounts due to either CONFORMA or SUMITOMO under this Agreement shall be paid by wire
transfer to such bank account as CONFORMA or SUMITOMO, as the case may be, may direct from
time to time. All bank expenses incurred by CONFORMA or SUMITOMO in making such wire
transfer shall be on its own account.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>All payments required under this Agreement shall be made in USD.</TD>
</TR>

</TABLE>
</DIV>
<P align="right" style="font-size: 10pt"><!-- Folio -->page 25<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>


<DIV style="font-family: Helvetica,Arial,sans-serif">
<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>



<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">


<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><U><B>13.</B></U>&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD> <U><B>CONFIDENTIALITY</B></U></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>13.1.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Non-disclosure</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>SUMITOMO and CONFORMA agree to hold in strict confidence any and all information disclosed
by the other and identified in writing as confidential whether disclosed prior to the
Effective Date or thereafter (&#147;Confidential Information&#148;), in accordance with these efforts
taken by each Party to protect its own information, data or other tangible or intangible
property that it regards as proprietary or confidential but using not less than reasonable
diligent efforts.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>13.2.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Limited Purposes</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The receiving Party shall not use the Confidential Information for any purpose other than in
connection with exercising its rights and fulfilling its obligations hereof. The receiving
Party will not disclose any such Confidential Information to any person other than to its
officers, employees, legal counsel or technical advisors, or to officers, employees, legal
counsel or technical advisors of any of its Affiliates, provided that they have a clear need
to know such Confidential Information in connection with the performance of their
professional responsibilities under this Agreement, and provided further that they are bound
by the confidentiality and non-use obligations substantially similar to those in this
Section&nbsp;13. The receiving Party shall further take all reasonable steps to prevent its
officers, employees, legal counsel or technical advisors, or any others having access to the
Confidential lnformation, from disclosing to any Third Party or making unauthorized use of
any Confidential Information, or from committing any acts or making any omissions that may
result in a violation of this Section&nbsp;13.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>13.3.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Exceptions</B></TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="6%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"><B>13.3.1.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Information Otherwise Available</B></TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Neither Party shall have any obligation of confidentiality or non-use with respect to any
portion of the Confidential lnformation which:</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="6%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(i)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>at the time of disclosure by the other Party, is in the public domain;</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(ii)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>after disclosure by the other Party, enters the public domain by means other
than a breach of this Agreement by the receiving Party;</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(iii)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>the receiving Party can establish by competent proof is in its possession at
the time of disclosure by the other Party or thereafter is independently developed by
persons in its employment who had no contact with and were not aware of the content of
the Confidential lnformation; or</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(iv)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>the receiving Party obtains from a Third Party not bound by a duty of
confidentiality.</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="5%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"><B>13.3.2.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Governmentally Required Disclosures</B></TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Each Party may disclose Confidential Information disclosed to it by the other Party to the
extent that such disclosure is reasonably necessary for the following reasons:</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="6%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(i)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>for regulatory filings, including without limitation filings with the U.S.
Securities and Exchange Commission, and filings with regulatory authorities permitted
hereunder;</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(ii)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>to comply with a subpoena or an order issued by a court or other tribunal of
competent jurisdiction, provided however, that the receiving Party shall immediately
provide a notice to the disclosing Party so that the disclosing Party may seek a</TD>
</TR>

</TABLE>
</DIV>
<P align="right" style="font-size: 10pt"><!-- Folio -->page 26<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">


<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>protective order or other remedy from relevant court or tribunal.</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>13.4.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Publication Procedure</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>When a Party plans to publish the results of the studies conducted in the course of the
development in and outside Territory, such Party shall submit the draft of the publication,
translated into English, to the other Party at least six (6)&nbsp;weeks prior to the planned
submission for publication for approval. Any such publication shall need the other Party&#146;s
prior written consent, which shall not be unreasonably withheld. Any comment, reasonable
request for modification, or reasonable rejection must be made within four (4)&nbsp;weeks from
receipt of the draft. Thereafter, the draft is deemed to be approved. However, for the
elimination of any doubt, CONFORMA will have the sole right to decide upon its own
publication strategy in the Territory.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>13.5.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Return of Information</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Unless otherwise set forth in this Agreement, title and all rights to, and emanating from,
the ownership of all Confidential Information disclosed under this Agreement shall remain
vested in the disclosing Party. Upon written request of the disclosing Party, the receiving
Party shall return to the disclosing Party all written materials and documents within sixty
(60)&nbsp;days, as well as any computer software or other media, in their possession, made
available or supplied by the disclosing Party to the receiving Party that contains
Confidential Information, together with any copies thereof, except for one copy which may be
retained by the receiving Party only for the purpose of determining the receiving Party&#146;s
continuing obligations or exercising its rights hereunder.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>13.6.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Additional Permitted Disclosures</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Each Party may provide the Confidential Information to a Third Party which is interested in
obtaining the license or sublicense of the Product in its Territory, provided that such
Third Party has signed a confidentiality agreement containing essentially similar provisions
of confidentiality as contemplated hereof. In addition, CONFORMA may disclose the terms and
conditions of this Agreement to potential investors or financial advisors for purposes of
due diligence in connection with a financing or other financial transaction involving
CONFORMA.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>13.7.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Terms and Conditions of this Agreement</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The Parties agree to keep the terms and conditions of this Agreement confidential and
neither Party shall disclose any such terms and conditions to the public or to Third
Parties, except as set forth in Sections&nbsp;13.2, 13.3 and 13.6, without the prior written
consent of the other Party.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>13.8.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Previous Confidential Agreement</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Upon the execution of this Agreement, information which has been protected by the provisions
of the Secrecy Agreement on &#147;SM-5887&#147; executed between the Parties on August&nbsp;12, 2004, shall
be covered by this Section&nbsp;13 and the provisions of the above Secrecy Agreement shall no
longer be effective.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The provisions of this Section&nbsp;13 shall survive the termination or expiration of this
Agreement for ten (10)&nbsp;years.</TD>
</TR>

</TABLE>
</DIV>
<P align="right" style="font-size: 10pt"><!-- Folio -->page 27<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">


<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><U><B>14.</B></U>&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD> <U><B>TERM AND TERMINATION</B></U></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>14.1.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Expiration</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Unless sooner terminated pursuant to the provisions hereof, this Agreement shall expire on
the date when the Initial Period has expired in all the countries in the Territory.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>14.2.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Termination by CONFORMA</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>In the occurrence of safety or toxicology issues CONFORMA may terminate this Agreement at
any time by providing SUMITOMO with thirty (30)&nbsp;days&#146; prior written notice.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>14.3.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Termination for Breach</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Upon a material breach of any term of this Agreement or the Supply Agreement by one Party,
the other Party may give written notice of such breach to the breaching Party. Should the
breaching Party fail to cure such breach within sixty (60)&nbsp;days of such notice, the other
Party may terminate this Agreement with further sixty (60)&nbsp;days&#146; notice. In addition to
this right to terminate this Agreement in its entirety, SUMITOMO shall have the right to
terminate the rights granted to CONFORMA under this Agreement on a country-by-country basis
as set forth in Sections&nbsp;4.2.3, 5.2 and 5.6.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>14.4.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Termination for Bankruptcy</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>This Agreement may be terminated by SUMITOMO within thirty (30)&nbsp;days upon written notice in
case CONFORMA becomes insolvent or makes an assignment for the benefit of creditors or
become involved in receivership, bankruptcy or other insolvency or debtor relief
proceedings, or any similar proceedings, or in proceedings, voluntary or forced, whereby
CONFORMA is limited in the free and unrestrained exercise of its own judgment as to the
carrying out of the terms of this Agreement.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>14.5.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Termination for Patent Challenge</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Until the expiry of all Patents in all countries in the Territory, SUMITOMO shall have the
right to terminate this Agreement if CONFORMA or its Affiliate takes, or actively assists a
Third Party in taking, any action to challenge or contest the title or validity of any of
the Patents.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>14.6.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Termination for Change of Control</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>In addition to the rights under Section&nbsp;5.6 in case a Change in Control occurs for CONFORMA
and the Third Party in such Change of Control transaction has a Competing Product in the
Territory (&#147;Competing Party&#148;), CONFORMA shall notify SUMITOMO of this event and the Parties
shall discuss in good faith how to ensure that sale of the Product is not adversely affected
by the Change of Control, and modify this Agreement as necessary. If the Parties are unable
to reach an agreement after ninety (90)&nbsp;days, SUMITOMO shall have thirty (30)&nbsp;days to
terminate this Agreement with sixty (60)&nbsp;days&#146; written notice to CONFORMA. For purposes of
this Section&nbsp;14.6, a &#147;Change of Control&#148; shall mean a transaction in which a single Third
Party becomes the beneficial owner of fifty percent (50%) or more of the combined voting
power of the outstanding securities of CONFORMA or a sale or other disposition to a Third
Party of all or substantially all of the assets or business of CONFORMA, by means of a
merger, reorganization or similar corporate transaction.</TD>
</TR>

</TABLE>
</DIV>
<P align="right" style="font-size: 10pt"><!-- Folio -->page 28<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">


<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>14.7.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Consequences of Termination</B></TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="6%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left"><B>14.7.1.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Responsibilities of CONFORMA</B></TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="5%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Upon the termination by CONFORMA pursuant to Section&nbsp;14.2. or the termination by
SUMITOMO pursuant to Section&nbsp;14.3., 14.4., and 14.5., CONFORMA shall:</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="5%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(i)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>transfer and assign to SUMITOMO or its designee CONFORMA&#146;s right and title to
all INDs and NDAs relating to the Product and all other applications, clinical trial
agreements (to the extent assignable and non-cancelable) and data obtained in the
course of the Development;</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(ii)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>provide to SUMITOMO or its designee all existing and reasonably available
marketing information; and</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(iii)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>grant to SUMITOMO a non-exclusive, perpetual, royalty-free license, with a
right to sublicense, of the Improvements to develop, register, manufacture, import,
use, market, promote, distribute and sell the Compound and/or Product in the Territory.</TD>
</TR>

</TABLE>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 5%">In addition to the foregoing, in the event that the termination notice under
Section&nbsp;14.5. is issued by SUMITOMO after the initiation of any clinical trials for the
Product by CONFORMA in the USA, CONFORMA shall, at its cost and expenses, complete any
ongoing trial to which the patients have already been enrolled before the issuance of
the termination notice. However, from the issuance of the termination notice until the
effective date of the termination notice, CONFORMA is not required to initiate any new
studies.
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 5%"><B>14.7.2. Responsibilities of SUMITOMO</B>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 5%">Upon termination by CONFORMA pursuant to Section&nbsp;14.3, SUMITOMO shall grant to CONFORMA
for the Territory an exclusive, perpetual paid-up license, including a right to sublicense,
to all the Patents and Know-how, which SUMITOMO has a right as of the termination date, to
the extent necessary for CONFORMA or its Sublicensees to continue all pending Development
activities or marketing and sales activities relating to the Product in the Territory.
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 5%"><B>14.7.3. Regulatory Responsibilities of Both Parties</B>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 5%">Even after the termination for any ground, each Party shall comply with the regulatory
requirements which the Regulatory Authority of the relevant countries imposes on the
Parties, if any.
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 5%"><B>14.7.4. Ancillary Agreements</B>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt; margin-left: 5%">Unless otherwise agreed in the Supply Agreement or otherwise by the Parties, the
termination of this Agreement with respect to all countries in the Territory in entirety
shall cause the automatic termination of all ancillary agreements related hereto, including
but not limited to Supply Agreement.
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>14.8.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Outstanding Payments</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Termination of this Agreement by a Party, for any reason, will not release CONFORMA from any
obligation to make any payments to SUMITOMO which were due and payable prior to the
effective date of termination.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>14.9.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Survival Clauses</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Even after this Agreement is terminated or has expired in all countries within the
Territory, the following Sections shall survive in addition to any Sections which by their
terms survive</TD>
</TR>

</TABLE>
</DIV>
<P align="right" style="font-size: 10pt"><!-- Folio -->page 29<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">


<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>termination or expiration of this Agreement: Sections&nbsp;1, the first paragraph of Section&nbsp;2.3,
Section&nbsp;6, 7.1, 7.2, 7.4, 7.5, 8.2, 8.5, 9.5, 9.6, 10, 11, 12, 13, 14.7, 14.8, 14.9, 15,
16.5 and 17.</TD>
</TR>

<TR>
    <TD style="font-size: 12pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><U><B>15.</B></U>&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD> <U><B>INDEMNIFICATION</B></U></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>15.1.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Indemnification by SUMITOMO</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Subject only to the provisions of this Agreement and the Supply Agreement (if executed),
SUMITOMO hereby agrees to indemnify and hold harmless CONFORMA, its Affiliates and
Sublicensees, and the officers, directors, agents, representatives and employees of each of
them, upon demand, against all losses, costs, claims, proceedings, actions, damages,
liabilities, penalties and expenses, including reasonable legal fees and expenses
(&#147;Losses&#148;), suffered or incurred by any of them, arising out of, resulting from or in
connection with claims brought by a Third Party that are based upon:</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="7%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(i)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>the performance or breach of this Agreement and the Supply Agreement (if
executed) by SUMITOMO; or</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(ii)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>non-compliance of the Compound or the Product to the Specifications, provided
that the Compound or Product is supplied by SUMITOMO or its Affiliate; or</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(iii)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>the development activities, regulatory approval, distribution, sale,
marketing and promotion of the Product outside the Territory by SUMITOMO, its
Affiliates or its Licensees; or</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(iv)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>except as expressly set forth in Section&nbsp;15.2, any damage or injury to a
Third Party arising from any use or misuse of the Product sold by SUMITOMO, its
Affiliates or its Licensees except for those sold to CONFORMA, its Affiliates, or the
Sublicensees, including any adverse effects caused by or arising from the Product;</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR>
<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" style="background: transparent">&nbsp;</TD>
    <TD align="left" colspan="3">&nbsp;except to the extent such Losses are due to the gross negligence or willful misconduct, or
failure to act of CONFORMA.</TD>
</TR>
</TABLE>
</DIV>


<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="5%" nowrap align="left"><B>15.2.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Indemnification by CONFORMA</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Subject only to the provisions of this Agreement and the Supply Agreement (if executed),
CONFORMA hereby agrees to indemnify and hold harmless SUMITOMO, its Affiliates, and
Licensees, and the officers, directors, agents, representatives and employees of each of
them, upon demand, against all Losses suffered or incurred by any of them, arising out of,
resulting from or in connection with claims brought by a Third Party that are based upon:</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="8%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(i)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>the performance or breach of this Agreement and the Supply
Agreement (if executed) by CONFORMA;</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(ii)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>the Development, registration of the Authorization, distribution, sale,
marketing and promotion of the Product in the Territory by CONFORMA, its Affiliates or
the Sublicensees;</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(iii)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>the packaging or labeling of the Product by CONFORMA or its Affiliates or a
Third Party on behalf of CONFORMA; or</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="5%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(iv)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>except as expressly set forth in Section&nbsp;15.1., any damage or injury to a
Third Party arising from any use or misuse or mishandling of the Product sold by
CONFORMA, its Affiliates or its Sublicensees, including any adverse effects caused by
or arising</TD>
</TR>

</TABLE>
</DIV>
<P align="right" style="font-size: 10pt"><!-- Folio -->page 30<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>


<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">


<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>from the Product;</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="5%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>except to the extent such Losses are due to the gross negligence or willful misconduct, or
failure to act of SUMITOMO.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>15.3.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Procedure</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>If any Third Party notifies any party hereto (the &#148;Indemnified Party&#147;) with respect to any
matter that may give rise to a claim for indemnification against the other Party hereto (the
&#148;Indemnifying Party&#147;) under this Section&nbsp;15, then the Indemnified Party will notify the
Indemnifying Party thereof promptly and in any event within thirty (30)&nbsp;days after receiving
any written notice from a Third Party; provided that no delay on the part of the Indemnified
Party in notifying the Indemnifying Party will relieve the Indemnifying Party from any
obligation hereunder unless, and then solely to the extent that, the Indemnifying Party is
prejudiced thereby. Once the Indemnified Party has given notice of the matter to the
Indemnifying Party, the Indemnified Party may defend against the matter in any manner it
reasonably may deem appropriate. If the Indemnifying Party notifies the Indemnified Party
within thirty (30)&nbsp;days after the date the Indemnified Party has given notice of the matter
that the Indemnifying Party is assuming the defense of such matter, then (i)&nbsp;the
Indemnifying Party will defend the Indemnified Party against the matter with counsel of its
choice reasonably satisfactory to the Indemnified Party, (ii)&nbsp;the Indemnified Party may
retain separate counsel at its sole cost and expense, except that the Indemnifying Party
will be responsible for the fees and expenses of such separate co-counsel to the extent the
Indemnified Party concludes in good faith that the Indemnifying Party and the Indemnified
Party have a potential or actual conflict of interest which necessitates separate counsel,
(iii)&nbsp;the Indemnified Party will not consent to the entry of a judgment or enter into any
settlement with respect to the matter without the written consent of the Indemnifying Party,
which shall not be withheld or delayed unreasonably, and (iv)&nbsp;the Indemnifying Party will
not consent to the entry of a judgment with respect to the matter or enter into any
settlement that does not include a provision whereby the plaintiff or claimant in the matter
releases the Indemnified Party from all liability with respect thereto, without the written
consent of the Indemnified Party, which shall not be withheld or delayed unreasonably.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>15.4.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>No Lost Profit</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Except as expressly set forth in this Agreement, the indemnification provisions set forth in
this Section&nbsp;15 shall be the exclusive remedy of the Parties for monetary damages under this
Agreement and the Supply Agreement (if executed). IN NO EVENT SHALL EITHER PARTY BE LIABLE
TO THE OTHER PARTY, ITS AFFILIATES, ITS LICENSEES, ITS SUBLICENSEES, AND ITS DEVELOPMENT
PARTNERS, OFFICERS, DIRECTORS, AGENTS, REPRESENTATIVES OR EMPLOYEES FOR ANY LOST PROFITS,
LOSS OF BUSINESS, LOSS OF CONTRACTS, DIMINISHED GOODWILL, DIMINISHED REPUTATION, OR
CONSEQUENTIAL, INDIRECT, INCIDENTAL, PUNITIVE, EXEMPLARY OR SPECIAL DAMAGES ARISING FROM OR
IN CONNECTION WITH THIS AGREEMENT.</TD>
</TR>

<TR>
    <TD style="font-size: 12pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><U><B>16.</B></U>&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD> <U><B>REPRESENTATIONS, WARRANTIES AND COVENANTS</B></U></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>16.1.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Execution of Agreement</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Each Party represents and warrants to the other Party at the time of the execution of this
Agreement that:</TD>
</TR>

</TABLE>
</DIV>
<P align="right" style="font-size: 10pt"><!-- Folio -->page 31<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">
<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>



<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">



</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="6%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(i)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>it has the cooperate power and authority to execute and deliver this
Agreement, and to perform its obligations hereunder;</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(ii)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>the execution, delivery and performance of this Agreement by each Party have
been duly and validly authorized and approved by proper corporate action on the part
of such Party; and</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="2%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(iii)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>it has no legal obligations or commitments to Third Parties inconsistent
with this Agreement.</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>16.2.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Additional SUMITOMO Representations</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>SUMITOMO represents and warrants to CONFORMA that:</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="6%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(i)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>it has not (in any manner that is inconsistent with or would interfere with
the rights granted to CONFORMA in this Agreement) previously assigned, transferred,
conveyed or otherwise encumbered any right, title or interest in or to the Patents or
Know-how in the Territory, granted to any Third Party any license to use the Patents
or Know-how in the Territory, or granted any covenant not to sue for any use of the
Patents or Know-how in the Territory ; and</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" style="background: transparent">&nbsp;</TD>
    <TD width="3%" nowrap align="left">(ii)</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>to the best of its knowledge, as of the Effective Date no claim of ownership,
invalidity or patent infringement has been asserted by any Third Party against
SUMITOMO with respect of the Patents or the Manufacturing Technology; provided,
however, that SUMITOMO is aware of the patent described in Annex 16.2.</TD>
</TR>

</TABLE>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>16.3.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Material Facts</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Each Party represents and warrants that it has disclosed all information in its possession
or control which is material to the other Party entering into this Agreement, and such
information does not contain any untrue statement of material fact or omit to state a
material fact.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>16.4.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Manufacture of Compound and Product</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>SUMITOMO warrants that the manufacturing processes of the Compound and Product are to
continue to be consistent with the Specifications, including conformity with GMP of Japan
and will, at all times that Product is supplied to CONFORMA, its Affiliates or its
Sublicensees, be consistent with the Specifications, including conformity with cGMP of the
USA.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>16.5.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Express Warranties</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The Parties intend and agree that this Agreement is not subject to the Uniform Commercial
Code in force in any state of the USA, and that no warranties exist beyond these stated in
this Agreement. EXCEPT FOR THE EXPRESS WARRANTIES SET FORTH IN THIS SECTION 16, NEITHER
PARTY MAKES ANY REPRESENTATIONS OR WARRANTIES, EXPRESS OR IMPLIED, EITHER IN FACT OR BY
OPERATION OF LAW, BY STATUTE OR OTHERWISE, AND SPECIFICALLY DISCLAIMS ANY OTHER WARRANTIES,
WHETHER WRITTEN OR ORAL, OR EXPRESS OR IMPLIED, INCLUDING ANY WARRANTY OF QUALITY,
MERCHANTABILITY OR FITNESS FOR A PARTICULAR USE OR PURPOSE OR ANY WARRANTY AS TO THE
VALIDITY OF ANY PATENTS OR THE NON-INFRINGEMENT OF ANY INTELLECTUAL PROPERTY RIGHTS OF THIRD
PARTIES.</TD>
</TR>

</TABLE>
</DIV>
<P align="right" style="font-size: 10pt"><!-- Folio -->page 32<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">


<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><U><B>17.</B></U>&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD> <U><B>MISCELLANEOUS PROVISIONS</B></U></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>17.1.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Headings</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The headings and captions used in this Agreement are for the convenience of the Parties only
and are not to be construed to define, limit or affect the construction or interpretation
hereof.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>17.2.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Severability</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>In the event that any provision of this Agreement is found to be invalid or unenforceable,
then such provision shall not render any other provision of this Agreement invalid or
unenforceable, and all other provisions shall remain in full force and effect and shall be
enforceable, unless the provisions which have been found to be invalid or unenforceable
shall substantially affect the remaining rights or obligations granted or undertaken by
either Party. The Parties agree to attempt to substitute for any invalid or unenforceable
provision which achieves to the greatest extent possible the economic objectives of the
invalid or unenforceable provision.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>17.3.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Entire Agreement; Amendment</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>This Agreement, including Annexes attached hereto, contains the entire agreement of the
Parties regarding the subject matter hereof and supersedes all prior agreements,
understandings or conditions, whether oral or written, regarding the same.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>This Agreement may not be changed, modified, amended or supplemented except by a written
agreement signed by both Parties. The Parties acknowledge and agree that they intend to
enter into a Supply Agreement which shall provide for additional rights and obligations on
each of their parts as set forth in each of those agreements.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>17.4.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Assignability</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>This Agreement and the rights and obligations established hereunder may not be assigned or
transferred by either Party without the prior written consent of the other Party, such
consent of which shall not to be unreasonably withheld, conditioned or delayed; provided,
however, that either Party may, without such consent, assign this Agreement and its rights
and obligations hereunder to an Affiliate, to the purchaser of all or substantially all of
its assets related to the Product or the Party&#146;s business, or to its successor entity or
acquirer in the event of a merger, consolidation or change in control of the Party. In
addition, CONFORMA acknowledges and agrees that SUMITOMO plans to merge with DAINIPPON
PHARMACEUTICAL CO., LTD. as of October&nbsp;1, 2005, and SUMITOMO&#146;s rights and obligations hereof
will be assigned to the surviving company, Dainippon Sumitomo Pharma Co., Ltd. upon such
merger. Notwithstanding the foregoing, in the event of a Change of Control in CONFORMA,
Section&nbsp;14.6 of this Agreement shall govern.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>17.5.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Independent Party</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>This Agreement does not constitute either Party as being the agent or legal representative
of the other for any purpose whatsoever. Neither Party is granted any right or authority to
assume or to create any obligation or responsibility, express or implied, on behalf of, or
in the name of the other, with regard to any manner or thing whatsoever, unless otherwise
specifically and express agreed upon in writing.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>17.6.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Notice and Reports</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>All notices, consents or approvals required by this Agreement shall be in writing and</TD>
</TR>

</TABLE>
</DIV>
<P align="right" style="font-size: 10pt"><!-- Folio -->page 33<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">
<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>



<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">


<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="4%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>personally delivered, or sent by internationally recognized overnight courier service or by
facsimile (confirmed by such international courier service) to the Parties at the following
addresses or such other addresses as may be designated in writing by the respective Party.
Notices shall be deemed effective on the seventh (7<SUP style="font-size: 85%; vertical-align: text-top">th</SUP>) day of sending, provided
that the receipt by the Party is confirmed by the record.</TD>
</TR>

</TABLE>
</DIV>
<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
<!-- Begin Table Head -->
<TR valign="bottom">
    <TD width="48%">&nbsp;</TD>
    <TD width="4%">&nbsp;</TD>
    <TD width="48%">&nbsp;</TD>
</TR>
<!-- End Table Head -->
<!-- Begin Table Body -->
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<U>If to CONFORMA</U>:
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top"><U>If to SUMITOMO</U>:</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Attn.: Vice President,
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Attn.: General Manager,</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Corporate Development
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Corporate Licensing</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;9393 Towne Centre Drive, Suite&nbsp;240
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;12-2, Kyobashi 1-chome,</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;San Diego, California 92121
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Chuo-ku, Tokyo, 104-8356, Japan</TD>
</TR>
<TR style="font-size: 6pt"><TD>&nbsp;</TD></TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Tel-No: (858)&nbsp;657-0300
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Tel-No: &#043;81-3-5159-2511</TD>
</TR>
<TR style="font-size: 6pt"><TD>&nbsp;</TD></TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Fax-No: (858)&nbsp;657-0343
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Fax-No: &#043;81-3-5159-1981</TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>


<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Any change in an address or fax number shall be the subject of a required notice under this
Agreement.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>17.7.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Waiver</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The failure of any Party to enforce at any time any provision of this Agreement, or any
right with respect thereto, or to exercise any election herein provided, shall in no way be
considered to be a waiver of such provision, right or election, or in any way affect the
validity of this Agreement. The exercise by any Party of any right or election under the
terms or covenants herein shall not preclude or prejudice any Party from exercising the same
or any other right it may have under this Agreement, irrespective of any previous action or
proceeding taken by the Parties hereunder.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>17.8.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Force Majeure</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>A Party shall not be liable for non-performance or delay in performance caused by any event
reasonably beyond the control of such Party including, without limitation, wars (declared or
undeclared), hostilities, revolutions, riots, civil disturbances, national emergencies,
strikes, lockouts, shortage of energy, computer viruses, epidemics, fires, floods,
earthquakes, other forces of nature, explosions, embargoes, or any other acts of God, or any
laws, proclamations, regulations, ordinances, or other acts or orders of any court,
government or governmental agency. Any occurrence of Force Majeure shall be reported
promptly to the other Party.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>17.9.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Dispute Resolution and Arbitration</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>In the event that any dispute arising between the Parties relating to this Agreement cannot
be resolved by their respective staffs, said dispute shall be referred promptly to the
Managing Director of SUMITOMO and the Chief Executive Officer of CONFORMA, who shall make a
good faith effort to resolve the matter within ninety (90)&nbsp;days from the date of any such
referral. If the matter has not been resolved utilizing the process set forth above, either
or both Parties may elect to pursue definitive resolution through binding arbitration, which
the Parties agree to accept in lieu of litigation or other legally available remedies,
except for injunctive relief where such relief is necessary to protect a Party from
irreparable harm pending the outcome of arbitration. Any such arbitration shall be settled
in</TD>
</TR>

</TABLE>
</DIV>
<P align="right" style="font-size: 10pt"><!-- Folio -->page 34<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">


<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>accordance with the Rules of Arbitration of the International Chamber of Commerce by three
arbitrators chosen in accordance with said Rules.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The arbitration will be conducted in English and will be held in the city of Honolulu,
Hawaii. Judgment upon the award rendered may be entered in any court having jurisdiction
thereof.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Nothing in this Section&nbsp;17.9 will preclude any Party from seeking interim or provisional
relief from a court of competent jurisdiction, including a temporary restraining order,
preliminary injunction or other interim equitable relief, concerning a dispute either prior
to or during any arbitration if necessary to protect the interests of such Party or to
preserve the status quo pending the arbitration proceeding.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>17.10.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Applicable Law</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>This Agreement shall be governed by and construed in accordance with the laws of the State
of New York, without reference to the principles of conflict of laws that would result in
the application of any law other than the State of New York.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>17.11.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Language</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The language of this Agreement and of any communication between the Parties shall be in
English unless otherwise mutually agreed.</TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left"><B>17.12.</B></TD>
    <TD width="1%">&nbsp;</TD>
    <TD><B>Counterparts</B></TD>
</TR>

<TR>
    <TD style="font-size: 6pt">&nbsp;</TD>
</TR><TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="left">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>This Agreement shall be executed in two counterparts, each of which shall be considered and
shall have the force and effect of an original.</TD>
</TR>

</TABLE>
</DIV>
<P align="right" style="font-size: 10pt"><!-- Folio -->page 35<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV style="margin-top: 6pt"><TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">



</TABLE>
</DIV>
<DIV align="left" style="font-size: 10pt; margin-top: 6pt">IN WITNESS WHEREOF, the Parties have executed this Agreement by their duly authorized
representatives, as of the day and year first written above.
</DIV>

<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
<!-- Begin Table Head -->
<TR valign="bottom">
    <TD width="38%">&nbsp;</TD>
    <TD width="20%">&nbsp;</TD>
    <TD width="38%">&nbsp;</TD>
</TR>
<!-- End Table Head -->
<!-- Begin Table Body -->
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px"><B>Conforma Therapeutics Corporation</B>
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top"><B>Sumitomo Pharmaceuticals Co., Ltd.</B></TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">June&nbsp;23, 2005
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">June&nbsp;23, 2005</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">/s/ Lawrence C. Fritz, Ph.D.
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">/s/ Yasuo Okamoto</TD>
</TR>
<TR style="font-size: 1px">
    <TD valign="top" style="border-top: 1px solid #000000"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top" style="border-top: 1px solid #000000">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Lawrence C. Fritz, Ph.D.
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Yasuo Okamoto</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">President and Chief Executive Officer
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">President</TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>


<P align="right" style="font-size: 10pt"><!-- Folio -->page 36<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

 <DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV align="right" style="font-size: 10pt; margin-top: 12pt">Annex 1.6
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 18pt">Compound
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">Amrubicin Hydrochloride (SM-5887) is anthracycline anti-cancer agent.
</DIV>

<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
<!-- Begin Table Head -->
<TR valign="bottom">
    <TD width="28%">&nbsp;</TD>
    <TD width="2%">&nbsp;</TD>
    <TD width="70%">&nbsp;</TD>
</TR>
<!-- End Table Head -->
<!-- Begin Table Body -->
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Chemical name:
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">(&#043;)-(7 S,9
S)-9-acetyl-9-amino-7-&#091;(2-deoxy-<font FACE="SYMBOL">&#098;</font>-D-<I>erythro</I>-pentopyranosyl)oxy &#093; - 7,8,9, <br>10-tetrahydro-6,11-dihydroxy-5,12-naphthacenedione
hydrochloride</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Nonproprietry name:
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Amrubicin (INN) Hydrochloride</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Additional name:
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">SM-5887</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Structural formula:</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top"><IMG src="d44563d4456302.gif" alt="(FORMULA)"></TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>


<P align="right" style="font-size: 10pt"><!-- Folio -->page 37<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">
<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>



<DIV align="right" style="font-size: 10pt; margin-top: 12pt">Annex 1.27
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 18pt">Patents
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 12pt"><U>1. Formulation</U>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">Title: STABILIZED ANTHRACYCLINE PREPARATION CONTAINING L-CYSTEINE
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">Japan: 2603480 (registered)
</DIV>

<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
<!-- Begin Table Head -->
<TR valign="bottom">
    <TD width="34%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="15%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="7%">&nbsp;</TD>
    <TD width="1%">&nbsp;</TD>
    <TD width="7%">&nbsp;</TD>
    <TD width="5%">&nbsp;</TD>
    <TD width="21%">&nbsp;</TD>
</TR>
<TR style="font-size: 8pt" valign="bottom">
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center">Date of</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center">&nbsp;</TD>
</TR>
<TR style="font-size: 8pt" valign="bottom">
    <TD nowrap align="left" style="border-bottom: 1px solid #000000">Countries</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" style="border-bottom: 1px solid #000000">Application</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" colspan="3" style="border-bottom: 1px solid #000000">Patent Number</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="center" style="border-bottom: 1px solid #000000">Status</TD>
</TR>

<!-- End Table Head -->
<!-- Begin Table Body -->
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">United States
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">1988/8/2
</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="right" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">4952566</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">registered</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Canada
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">1988/8/5
</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="right" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">1324959</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">registered</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Austria
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">1988/8/4
</TD>
    <TD>&nbsp;</TD>
    <TD nowrap colspan="3" align="center" valign="top">EP 302729
</TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">registered</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Belgium
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">1988/8/4
</TD>
    <TD>&nbsp;</TD>
    <TD nowrap colspan="3" align="center" valign="top">EP 302729
</TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">registered</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Swizerland
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">1988/8/4
</TD>
    <TD>&nbsp;</TD>
    <TD nowrap colspan="3" align="center" valign="top">EP 302729
</TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">registered</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Germany
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">1988/8/4
</TD>
    <TD>&nbsp;</TD>
    <TD nowrap colspan="3" align="center" valign="top">EP 302729
</TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">registered</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Spain
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">1988/8/4
</TD>
    <TD>&nbsp;</TD>
    <TD nowrap colspan="3" align="center" valign="top">EP 302729
</TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">registered</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">France
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">1988/8/4
</TD>
    <TD>&nbsp;</TD>
    <TD nowrap colspan="3" align="center" valign="top">EP 302729
</TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">registered</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">United Kingdom
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">1988/8/4
</TD>
    <TD>&nbsp;</TD>
    <TD nowrap colspan="3" align="center" valign="top">EP 302729
</TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">registered</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Greece
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">1988/8/4
</TD>
    <TD>&nbsp;</TD>
    <TD nowrap colspan="3" align="center" valign="top">EP 302729
</TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">registered</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Italy
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">1988/8/4
</TD>
    <TD>&nbsp;</TD>
    <TD nowrap colspan="3" align="center" valign="top">EP 302729
</TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">registered</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Netherland
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">1988/8/4
</TD>
    <TD>&nbsp;</TD>
    <TD nowrap colspan="3" align="center" valign="top">EP 302729
</TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">registered</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Sweden
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">1988/8/4
</TD>
    <TD>&nbsp;</TD>
    <TD nowrap colspan="3" align="center" valign="top">EP 302729
</TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">registered</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Denmark
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">1988/8/4
</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="right" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">173317</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">registered</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Finland
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">1988/8/1
</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="right" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">91483</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">registered</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Norway
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">1988/8/3
</TD>
    <TD>&nbsp;</TD>
    <TD nowrap align="right" valign="top">&nbsp;</TD>
    <TD align="right" valign="top">175134</TD>
    <TD nowrap valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="CENTER" valign="top">registered</TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt"><U>2. </U><B>&#091;***&#093;</B>

</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt"><U>3. </U><B>&#091;***&#093;</B>

</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt"><U>4. </U><B>&#091;***&#093;</B>

</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt"><U>5. </U><B>&#091;***&#093;</B>

</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt"><U>6. </U><B>&#091;***&#093;</B>

</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt"><U>7. </U><B>&#091;***&#093;</B>

</DIV>

<DIV align="left">
<DIV style="font-size: 3pt; margin-top: 16pt; width: 18%; border-top: 1px solid #000000">&nbsp;</DIV>
</DIV>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
<TR>
    <TD width="3%"></TD>
    <TD width="1%"></TD>
    <TD width="96"></TD>
</TR>

<TR valign="top">
    <TD nowrap align="left"><B>***</B></TD>
    <TD>&nbsp;</TD>
    <TD><B>Confidential Treatment Requested</B></TD>
</TR>

</TABLE>

<P align="right" style="font-size: 10pt"><!-- Folio -->page 38<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV align="right" style="font-size: 10pt; margin-top: 12pt">Annex 1.30
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 18pt">Specifications
</DIV>


<DIV align="Center" style="font-size: 10pt; margin-top: 6pt"><B>&#091;***&#093;</B>

</DIV>

<DIV align="left">
<DIV style="font-size: 3pt; margin-top: 16pt; width: 18%; border-top: 1px solid #000000">&nbsp;</DIV>
</DIV>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
<TR>
    <TD width="3%"></TD>
    <TD width="1%"></TD>
    <TD width="96"></TD>
</TR>

<TR valign="top">
    <TD nowrap align="left"><B>***</B></TD>
    <TD>&nbsp;</TD>
    <TD><B>Confidential Treatment Requested</B></TD>
</TR>

</TABLE>

<P align="right" style="font-size: 10pt"><!-- Folio -->page 39<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV align="right" style="font-size: 10pt; margin-top: 12pt">Annex 4.2.3
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 18pt">Development Plan
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt"><B>&#091;***&#093;</B>

</DIV>

<DIV align="left">
<DIV style="font-size: 3pt; margin-top: 16pt; width: 18%; border-top: 1px solid #000000">&nbsp;</DIV>
</DIV>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
<TR>
    <TD width="3%"></TD>
    <TD width="1%"></TD>
    <TD width="96"></TD>
</TR>

<TR valign="top">
    <TD nowrap align="left"><B>***</B></TD>
    <TD>&nbsp;</TD>
    <TD><B>Confidential Treatment Requested</B></TD>
</TR>

</TABLE>

<P align="right" style="font-size: 10pt"><!-- Folio -->page 40<!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>

<DIV style="font-family: Helvetica,Arial,sans-serif">

<DIV align="center" style="font-size: 10pt; margin-top: 18pt">License Agreement Amrubicin Hydrochloride (SM-5887)<BR>
Sumitomo Pharmaceuticals Co., Ltd. &#151; Conforma Therapeutics Corporation
</DIV>


<DIV align="right" style="font-size: 10pt; margin-top: 12pt">Annex 16.2
</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 12pt"><B>&#091;***&#093;</B>
</DIV>

<DIV align="left">
<DIV style="font-size: 3pt; margin-top: 16pt; width: 18%; border-top: 1px solid #000000">&nbsp;</DIV>
</DIV>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
<TR>
    <TD width="3%"></TD>
    <TD width="1%"></TD>
    <TD width="96"></TD>
</TR>

<TR valign="top">
    <TD nowrap align="left"><B>***</B></TD>
    <TD>&nbsp;</TD>
    <TD><B>Confidential Treatment Requested</B></TD>
</TR>

</TABLE>


<P align="right" style="font-size: 10pt"><!-- Folio -->page 41<!-- /Folio -->
</DIV>

</BODY>
</HTML>
</TEXT>
</DOCUMENT>
