FIRST HORIZON PHARMACEUTICAL CORP
EXHIBIT 10.41
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<BR></FONT><FONT SIZE=2><B>Exhibit&nbsp;10.41    <BR>    </B></FONT></P>

<P ALIGN="CENTER"><FONT SIZE=2>November&nbsp;30,
2004 </FONT></P>

<P><FONT SIZE=2>Greg
Yonko<BR>
Sr. Vice President, Purchasing<BR>
McKesson Corporation<BR>
One Post Street<BR>
San Francisco, CA 94104-5296 </FONT></P>

<DL compact>
<DT style='margin-bottom:-11pt;'><FONT SIZE=2><B>RE:</B></FONT></DT><DD><FONT SIZE=2><B>Amendment to Inventory Management Agreement by and between Supplier and McKesson Corporation dated 6/10/03 ("Amendment")</B></FONT></DD></DL>

<P><FONT SIZE=2>Dear
Mr.&nbsp;Yonko: </FONT></P>

<P><FONT SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;This
letter serves to amend the above-referenced Inventory Management Agreement ("Agreement") between First Horizon ("FHPC") and McKesson Corporation ("Wholesaler") dated 6/10/2003. </FONT></P>

<P><FONT SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The
Agreement shall be amended as follows: </FONT></P>

<UL>

<P><FONT SIZE=2><B> Article&nbsp;1  </B></FONT></P>

</UL>
<DL compact>
<DT style='margin-bottom:-11pt;'><FONT SIZE=2>1.</FONT></DT><DD><FONT SIZE=2>The
following definition shall be added in Article&nbsp;1 as section&nbsp;1.15.
<BR><BR></FONT></DD><DT style='margin-bottom:-11pt;'><FONT SIZE=2><I>1.15</I></FONT></DT><DD><FONT SIZE=2><I>"Contract Year" means the calendar year beginning on January&nbsp;1<SUP>st</SUP> and ending December&nbsp;31<SUP>st</SUP>.
<BR><BR> </I></FONT></DD><DT style='margin-bottom:-11pt;'><FONT SIZE=2>2.</FONT></DT><DD><FONT SIZE=2>The following definition shall be added in Article&nbsp;1 as section&nbsp;1.16.
<BR><BR></FONT></DD><DT style='margin-bottom:-11pt;'><FONT SIZE=2><I>1.16</I></FONT></DT><DD><FONT SIZE=2><I>"Economic Benefit" means the total savings received or realized by Wholesaler that derive from price breaks, purchases made at the Old Price, Product
discounts, off invoice allowances, promotions, special offers, or price allowances.  </I></FONT></DD></DL>
<UL>

<P><FONT SIZE=2><B> Article&nbsp;2  </B></FONT></P>

</UL>
<DL compact>
<DT style='margin-bottom:-11pt;'><FONT SIZE=2>3.</FONT></DT><DD><FONT SIZE=2>The
following paragraph shall be added in Article&nbsp;2 as section&nbsp;2.1.
<BR><BR></FONT></DD><DT style='margin-bottom:-11pt;'><FONT SIZE=2><I>2.1</I></FONT></DT><DD><FONT SIZE=2><I>[</I></FONT><FONT SIZE=2><B><I>***]</I></B></FONT><FONT SIZE=2><I>. Such notification shall include the following information: (i)&nbsp;the
Product name, Product expiration date and lot number; (ii)&nbsp;</I></FONT><FONT SIZE=2><B><I>[***]</I></B></FONT><FONT SIZE=2><I>; (iii)&nbsp;the dollar amount of Product being
purchased; and (iv)&nbsp;</I></FONT><FONT SIZE=2><B><I>[***]</I></B></FONT><FONT SIZE=2><I>. In any event and subject to section&nbsp;2.4 <U>Purchase Limits</U>,
Wholesaler shall at all times maintain the Inventory Levels set forth in section&nbsp;2.3 <U>Inventory Levels</U>.</I></FONT><FONT SIZE=2>
<BR><BR></FONT></DD><DT style='margin-bottom:-11pt;'><FONT SIZE=2>4.</FONT></DT><DD><FONT SIZE=2>Delete
section&nbsp;2.2 in its entirety and replace with the following language:
<BR><BR></FONT></DD><DT style='margin-bottom:-11pt;'><FONT SIZE=2>2.2</FONT></DT><DD><FONT SIZE=2><I><U>Inventory Reports</U>. Wholesaler shall prepare inventory reports detailing the status of its Aggregate Inventory of Products by NDC
number ("<U>Inventory Reports</U>") and, for the duration of this Agreement, provide FHPC with monthly Inventory Reports. All such Inventory Reports shall be transmitted in EDI
(Electronic Data Interchange) format pursuant to Section&nbsp;2.7 and shall include such information as reasonably requested by FHPC, including the following:</I></FONT><FONT SIZE=2>
<BR><BR></FONT>
<DL compact>
<DT style='margin-bottom:-11pt;'><FONT SIZE=2><I>(a)</I></FONT></DT><DD><FONT SIZE=2><I>On hand inventory level by distribution center; includes all distribution centers and
<BR><BR> </I></FONT></DD><DT style='margin-bottom:-11pt;'><FONT SIZE=2><I>(b)</I></FONT></DT><DD><FONT SIZE=2><I> On order inventory level by distribution center; includes all distribution centers and
<BR><BR> </I></FONT></DD><DT style='margin-bottom:-11pt;'><FONT SIZE=2><I>(c)</I></FONT></DT><DD><FONT SIZE=2><I> Unit Sales report (EDI 852) which shall state sales out by distribution center; includes all distribution centers and
<BR><BR> </I></FONT></DD><DT style='margin-bottom:-11pt;'><FONT SIZE=2><I>(d)</I></FONT></DT><DD><FONT SIZE=2><I> Chargeback resubmission report (EDI 849) by distribution center, includes all distribution centers and
<BR><BR> </I></FONT></DD><DT style='margin-bottom:-11pt;'><FONT SIZE=2><I>(e)</I></FONT></DT><DD><FONT SIZE=2><I> Customer Outlet Reports (EDI 867) by distribution center, includes all distribution centers.</I></FONT><FONT SIZE=2>
<BR><BR></FONT></DD></DL>
</DD><DT style='margin-bottom:-11pt;'><FONT SIZE=2>5.</FONT></DT><DD><FONT SIZE=2>The
following paragraph shall be added in Article&nbsp;2 as section&nbsp;2.10. </FONT></DD></DL>
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<DL compact>
<DT style='margin-bottom:-11pt;'><FONT SIZE=2>2.10.</FONT></DT><DD><FONT SIZE=2><I><U>EFT Payments:</U> Beginning March&nbsp;31, 2005, Wholesaler shall remit all payments including credits to FHPCs account by 820 EFT
transmissions. In the event Wholesaler is unable to transmit the required payment at the time payment is due as a result of system failures or error, Wholesaler shall promptly notify the FHPC's
Finance Department for instructions on remitting payment.</I></FONT></DD></DL>
<BR>
<UL>

<P><FONT SIZE=2><B> Article&nbsp;4  </B></FONT></P>

</UL>
<DL compact>
<DT style='margin-bottom:-11pt;'><FONT SIZE=2>6.</FONT></DT><DD><FONT SIZE=2>The
following language shall be added in Article&nbsp;4 as section&nbsp;4.0.
<BR><BR></FONT></DD><DT style='margin-bottom:-11pt;'><FONT SIZE=2><I>4.0.</I></FONT></DT><DD><FONT SIZE=2><I>Wholesaler and FHPC acknowledge and agree that one of the purposes of this Agreement is for Wholesaler to receive some economic relief for a finite period of
time from price increases instituted by FHPC on a Product and as consideration for such relief Wholesaler shall provide certain reports to FHPC and maintain Inventory Levels as set forth in this
agreement. Wholesaler and FHPC agree that Wholesaler shall receive an Economic Benefit which equals at least </I></FONT><FONT SIZE=2><B><I>[***]</I></B></FONT><FONT SIZE=2><I> purchased by
Wholesaler during the Contract Year ("Targeted Economic Benefit").</I></FONT></DD></DL>

<P><FONT SIZE=2><I>In the event the actual Economic Benefit of a particular Product is less than the Targeted Economic Benefit of  </I></FONT><FONT SIZE=2><B><I>[***]</I></B></FONT><FONT SIZE=2><I>, then Wholesaler shall issue an invoice to FHPC for
the difference no later then January&nbsp;30<SUP>th</SUP> of the
following year. Such invoice shall include sufficient detail to allow FHPC to verify and audit Wholesaler's invoice. FHPC shall pay undisputed invoice amounts within 45&nbsp;days of FHPC's receipt
of invoice.</I></FONT></P>

<P><FONT SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Any
capitalized terms used in this Amendment, which are not otherwise defined herein, shall have the same meanings ascribed to them in the Agreement. All other terms and conditions of
the Agreement shall remain in full force and effect and unless as otherwise modified herein, shall also apply to the subject matter of this Amendment. In the event there is any inconsistency or
conflict between the provisions in this Amendment and those in the Agreement, the provisions in this Amendment shall supersede and control. </FONT></P>

<P><FONT SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Please
sign two copies of this letter agreement to acknowledge your acceptance of this amendment to the Agreement and return one signed copy to: First Horizon Pharmaceutical Corporation,
Attention: Kathy Lang, 6195 Shiloh Road, Alpharetta, GA, 30005. The second copy should be retained for your records. </FONT></P>

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Very truly yours,</FONT></TD>
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&nbsp;</FONT></TD>
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Kathy Lang<BR>
Sr. Director of Corporate Accounts</FONT></TD>
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Michael Mavrogordato<BR>
Vice President of Business Development &amp; Managed Care</FONT></TD>
<TD WIDTH="3%"><FONT SIZE=2><BR>&nbsp;</FONT></TD>
<TD COLSPAN=2><FONT SIZE=2><BR>
Greg Yonko<BR>
Sr. Vice President, Purchasing</FONT></TD>
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<TD COLSPAN=2><FONT SIZE=2><BR>
ACCEPTED AND AGREED:</FONT></TD>
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ACCEPTED AND AGREED:</FONT></TD>
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By:</FONT></TD>
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By:</FONT></TD>
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&nbsp;</FONT></TD>
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<TD WIDTH="44%"><FONT SIZE=2>/s/&nbsp;&nbsp;</FONT><FONT SIZE=2>MICHAEL MAVROGORDATO</FONT><FONT SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</FONT><HR NOSHADE><FONT SIZE=2> Michael Mavrogordato<BR>
VP Business Development<BR>
Name &amp; Title</FONT></TD>
<TD WIDTH="3%"><FONT SIZE=2>&nbsp;</FONT></TD>
<TD WIDTH="5%"><FONT SIZE=2>&nbsp;</FONT></TD>
<TD WIDTH="44%"><FONT SIZE=2>/s/&nbsp;&nbsp;</FONT><FONT SIZE=2>GREG YONKO</FONT><FONT SIZE=2>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</FONT><HR NOSHADE><FONT SIZE=2> Greg Yonko<BR>
SR VP<BR>
Name &amp; Title</FONT></TD>
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&nbsp;</FONT></TD>
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&nbsp;</FONT></TD>
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&nbsp;</FONT></TD>
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&nbsp;</FONT></TD>
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<TD COLSPAN=2><FONT SIZE=2><BR>
Dated:&nbsp;&nbsp;&nbsp;&nbsp;11/30/04</FONT></TD>
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<TD COLSPAN=2><FONT SIZE=2><BR>
Dated:&nbsp;&nbsp;&nbsp;&nbsp;12/10/04</FONT></TD>
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