BARRIER THERAPEUTICS INC
JOHNSON & JOHNSON CONSUMER COMPANIES, INC. - AMENDMENT NO.1 TO THE INTELLECTUAL
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<TYPE>EX-10.1
<SEQUENCE>2
<FILENAME>w01931exv10w1.htm
<DESCRIPTION>JOHNSON & JOHNSON CONSUMER COMPANIES, INC. - AMENDMENT NO.1 TO THE INTELLECTUAL PROPERTY TRANSFER AND LICENSE AGREEMENT DATED AS OF SEPTEMBER 7, 2004.
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<DIV style="font-family: 'Times New Roman',Times,serif">
<div align="right" style="font-size: 10pt">Exhibit 10.1</div>
<P align="center" style="font-size: 10pt"><B>AMENDMENT NO. 1 TO JJCC INTELLECTUAL PROPERTY TRANSFER AND LICENSE AGREEMENT</B>



<P align="left" style="font-size: 10pt">This Amendment No.&nbsp;1 (the &#147;JJCC Amendment&#148;) is made and entered into as of
September&nbsp;7, 2004 by and between Johnson &#038; Johnson Consumer Companies, Inc., a
New Jersey corporation having an address at 199 Grandview Road, Skillman, New
Jersey 08558 (hereinafter referred to as &#147;JJCC&#148;) and Barrier Therapeutics,
Inc., a Delaware corporation having an address at 600 College Road East, Suite
3200, Princeton, New Jersey 08540 (hereinafter referred to as &#147;Barrier&#148;).


<P align="left" style="font-size: 10pt">WHEREAS, JJCC and Barrier are parties to that certain Intellectual Property
Transfer and License Agreement dated May&nbsp;6, 2002 (the &#147;Original JJCC
Agreement&#148;);


<P align="left" style="font-size: 10pt">WHEREAS, JJCC and Barrier desire to make certain amendments to the Original
JJCC Agreement pursuant to the terms of this JJCC Amendment; and


<P align="left" style="font-size: 10pt">WHEREAS, contemporaneously with the execution and delivery hereof, Barrier and
Janssen Pharmaceutica Products, L.P., an Affiliate of JJCC (&#147;Janssen&#148;), are
entering into an amendment to that certain Intellectual Property Transfer and
License Agreement between Barrier and Janssen dated May&nbsp;6, 2002.


<P align="left" style="font-size: 10pt">NOW, THEREFORE, in consideration of the above premises and the covenants
contained herein, the parties agree as follows:


<P>

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<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="1%" nowrap align="right">1.</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The Original JJCC Agreement is hereby amended as follows:</TD>
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<P>

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<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="3%" style="background: transparent">&nbsp;</TD>
    <TD width="1%" nowrap align="right">1.1.</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>The definition of &#147;JJCC Countries&#148; in Section&nbsp;1.15 of the
Original JJCC Agreement is hereby replaced in its entirety with the
following:</TD>
</TR>

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<P align="left" style="font-size: 10pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&#147;JJCC Countries shall mean Argentina, Australia, Belgium, Denmark,
Germany, Indonesia, Luxembourg, Mexico, New Zealand, Pakistan, Peru and
Venezuela.&#148;


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    <TD width="3%" style="background: transparent">&nbsp;</TD>
    <TD width="1%" nowrap align="right">1.2.</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Section&nbsp;2.1 of the Original JJCC Agreement is hereby replaced
in its entirety with the following:</TD>
</TR>

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<P align="left" style="font-size: 10pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&#147;Subject to Section&nbsp;2.2, JJCC hereby grants to Barrier the exclusive (even
as to JJCC and its Affiliates), royalty-free license with the unrestricted
right to grant sublicenses (subject to Section&nbsp;2.6 and Article&nbsp;5), under the
&#145;932 Patent Rights to (i)&nbsp;import, use, sell, offer for sale, and have sold &#145;932
Products in the &#145;932 Territory and (ii)&nbsp;make and have made &#145;932 Products
anywhere in the world in order to import, use, sell, offer for sale, and have
sold &#145;932 Products in the &#145;932 Territory. JJCC hereby grants to Barrier (i)
the Semi-exclusive (along with JJCC and its Affiliates), royalty-free license,
under the &#145;932 Patent Rights to import, use, sell, offer for sale, and have
sold &#145;932 Products in the JJCC Countries and (ii)&nbsp;the non-exclusive,
royalty-free license, under the


<P align="center" style="font-size: 10pt">&nbsp;
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<P align="left" style="font-size: 10pt">&#145;932 Patent Rights to make and have made &#145;932 Products anywhere in the world in
order to import, use, sell, offer for sale, and have sold &#145;932 Products in the
JJCC Countries. For purposes of this Agreement, the term &#147;Semi-exclusive&#148;
shall mean with, respect to a product, that at any given time only two entities
may commercialize such product in the country at issue, with such two entities
being (x)&nbsp;either JJCC, or a single Affiliate of JJCC, or a single third party
designated by JJCC, on the one hand, and (y)&nbsp;either Barrier, or a single
Barrier Affiliate, or a single third party designated by Barrier, on the other
hand. For avoidance of doubt, there shall be no field-of-use limitation on
the license granted pursuant to this Section&nbsp;2.1(a) regarding indications for
which &#145;932 Products may be used.&#148;


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<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="3%" style="background: transparent">&nbsp;</TD>
    <TD width="1%" nowrap align="right">1.3</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Section&nbsp;2.2 of the Original JJCC Agreement is hereby replaced
in its entirety with the following:</TD>
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<P align="left" style="font-size: 10pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&#147;JJCC retains, under the &#145;932 Patent Rights (i)&nbsp;the Semi-exclusive right
to import, use, sell, offer for sale, and have sold &#145;932 Products in the JJCC
Countries, (ii)&nbsp;the non-exclusive right to make and have made the &#145;932 Products
anywhere in the world in order to import, use, sell, offer for sale in the JJCC
Countries, and (iii)&nbsp;the non-exclusive right, including the unrestricted right
to grant sublicenses, to make, have made, import, use, sell, offer for sale,
and have sold products (other than the Diaper Dermatitis Product) for which
JJCC or its Affiliates can show through tangible dated evidence was under
development (having at least performed in vivo studies) or marketed by JJCC or
such Affiliate prior to the Execution Date. For avoidance of doubt, there
shall be no field-of-use limitation on the rights retained under this Section
2.2 regarding indications for which products may be used.&#148;


<P>

<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">
<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="3%" style="background: transparent">&nbsp;</TD>
    <TD width="1%" nowrap align="right">1.4</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Section&nbsp;2.5(b) of the Original JJCC Agreement is hereby
amended to replace the words &#147;in the &#145;932 Territory&#148; as they appear
twice in such section with the words &#147;anywhere in the world.&#148;</TD>
</TR>

<TR>
    <TD colspan="5">&nbsp;</TD>
</TR>
<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
    <TD width="3%" style="background: transparent">&nbsp;</TD>
    <TD width="1%" nowrap align="right">1.5</TD>
    <TD width="1%">&nbsp;</TD>
    <TD>Section&nbsp;8.6 of the Original JJCC Agreement is hereby amended
to delete the words &#147;in the &#145;932 Territory&#148; from clause (i).</TD>
</TR>

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<P align="left" style="font-size: 10pt">2.&nbsp;Capitalized terms used herein and not otherwise defined shall have the
meanings given to them in the Original JJCC Agreement.


<P align="left" style="font-size: 10pt">3.&nbsp;Except as expressly amended herein, all terms and conditions of the Original
JJCC Agreement shall remain in full force and effect.


<P align="left" style="font-size: 10pt">4.&nbsp;All matters affecting the interpretation, validity, and performance of this
JJCC Amendment shall be governed by the laws of the State of New York, USA,
without regard to its choice or conflict of law principles.


<P align="left" style="font-size: 10pt">5.&nbsp;This JJCC Amendment may be executed in one or more counterparts, each of
which shall for all purposes be deemed to be an original and all of which shall
constitute


<P align="center" style="font-size: 10pt">2
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<P align="left" style="font-size: 10pt">the same instrument. This JJCC Amendment may be executed by facsimile
signature which shall have the same force and effect as the original
signatures.


<P align="left" style="font-size: 10pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;IN WITNESS WHEREOF, and intending to be legally bound, the parties hereto
have caused this JJCC Amendment to be executed by their duly authorized
representatives as of the date first set forth above.

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    <TD width="48%">&nbsp;</TD>
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<TR valign="bottom">
    <TD colspan="3" valign="top" align="left">JOHNSON &#038; JOHNSON CONSUMER COMPANIES, INC.</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">By:
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">J. N. MATHESON
</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>

<TR style="font-size: 1px">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top"><HR size="1" noshade>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Print Name:
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">J. N. Matheson</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Print Title:
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">EVP RD&#038;E</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>

<TR valign="bottom">
    <TD colspan="3" valign="top" align="left">BARRIER THERAPEUTICS, INC.</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">By:
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">AL ALTOMARI</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>

<TR style="font-size: 1px">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top"><HR size="1" noshade>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>
<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Print Name:
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Al Altomari</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>

<TR valign="bottom">
    <TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Print Title:
</DIV></TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">Chief Commercial Officer</TD>
    <TD>&nbsp;</TD>
    <TD align="left" valign="top">&nbsp;</TD>
</TR>


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