SURMODICS INC
AMENDMENT TO THE 2003 EQUITY INCENTIVE PLAN
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<P align="right" style="font-size: 10pt"><B>EXHIBIT 10.1</B>



<P align="center" style="font-size: 10pt"><B>Amendment Adopted November&nbsp;15, 2004 by Board of Directors<BR>
and Approved by the Shareholders on January&nbsp;31, 2005<BR>
to the<BR>
SurModics, Inc.<BR>
2003 Equity Incentive Plan</B>



<P align="left" style="font-size: 10pt">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The number of shares reserved and available under the Plan is increased from 600,000 shares to
2,400,000 shares by hereby amending the second sentence of Section&nbsp;6 of the Plan to read in its
entirety as follows:



<P align="left" style="margin-left:3%; font-size: 10pt">&#147;Two Million Four Hundred Thousand (2,400,000) shares of Option Stock shall be reserved and
available for options and stock awards under the Plan; provided, however, that the total
number of shares of Option Stock reserved for options and stock awards under this Plan shall
be subject to adjustment as provided in Section&nbsp;12 of the Plan.&#148;


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