article_snippet: Cases of Crohn’s disease have exploded since the 1960s, and researchers now believe widespread use of the Pill may be one of the main reasons behind the dramatic rise.
article_snippet: researchers have found sex hormones in contraceptive Pills can weaken the gut, creating the perfect conditions for Crohnto develop.
article_snippet: Dr Khalili, said Crohn’s cases had risen ‘two or three-fold’ in the past 50 years, since widespread use of the Pill began.
article_snippet: Exactly why the Pill – taken by around 3.5 million women in Britain, a third of those of childbearing age – seems to raise the risk of Crohn’s remains unclear.
article_snippet: Overall, adult women are only a little more likely to have Crohn’s than adult men.
article_snippet: But twice as many women as men suffer from one of the main forms of Crohn’s, where the colon is affected.
article_snippet: Dr Khalili, who practises at Massachusetts General Hospital in Boston, stressed a woman was unlikely to get Crohn’s simply by using the Pill, and that genetics played a large role.
article_snippet: Dr Khalili said: ‘What’s very clear is that Crohnis not caused by oral contraceptive use by Crohn.
article_snippet: Crohn’s a combination of oral contraceptive use among individuals with a strong genetic predisposition to Crohn.
article_snippet: Crohn’s an interaction between these two that significantly increases the risk of an individual developing Crohn.
article_snippet: Cases of Crohn’s disease have exploded since the 1960s, and researchers now believe widespread use of the Pill may be one of the main reasons behind the dramatic rise .
article_snippet: Dr Khalili and Khalili colleagues are now looking at this in a study of 1,500 women, a third of whom have Crohn’s.
article_snippet: Dr Simon Anderson, a consultant gastroenterologist at London Bridge hospital, said the Pill appeared to act as a ‘trigger’ to developing Crohn’s.
article_snippet: ‘If you have a family history of Crohn’s, I would advise against starting on the Pill.
highlights_snippet: Found sex hormones  weakenz  gut creating perfect conditions for Crohn's .
  