article_snippet.sent: The condition is caused by a chromosomal defect.
article_snippet.sent: Children with Apert have bulging eyes that are usually wide-set and tilted down at the sides.
article_snippet.sent: Children with Apert may also have problems with tooth alignment due to jaw development problems, suffer from a cleft palate, and may have webbed fingers and toes.
article_snippet.sent: Apert syndrome is a genetic craniofacial abnormality that occurs in around one in 160,000 to 200,000 births.
article_snippet.sent: The condition is characterised by malformations of the skull, mid-face, hands and feet.
article_snippet.sent: Some children with the condition have fused fingers and toes.
article_snippet.sent: Children with Apert syndrome have very small eye orbits, meaning more of Children with Apert syndrome eyeball is exposed.