article_snippet.sent: This can mean a burn that had initially caused damage to the outer layer of skin (the epidermis) and the underlying tissue containing the hair follicles and sweat glands and smaller blood vessels (dermis) can become a 'full-thickness' burn.
article_snippet.sent: This is where there is damage to the third and final layer of skin - the subcutis, which contains larger blood vessels and nerves, and regulates the temperature of the skin and body.
article_snippet.sent: Full-thickness burns usually require extensive treatment, including skin grafts.