article_snippet.sent: Women who carry a mutated version of BRCA1 or another gene known as BRCA2 face a life-time risk of breast cancer of up to 70 per cent.
article_snippet.sent: If diagnosed, Women who carry a mutated version of BRCA1 or another gene known as BRCA2 face a severe threat of ovarian tumours.
article_snippet.sent: The researchers in Canada analysed 676 breast cancer patients who had one of the mutated genes, Nearly half (345) underwent oophorectomy after The researchers in Canada diagnosis.
article_snippet.sent: Having an oophorectomy was associated with a significant drop of 62 per cent in breast cancer death in women with a BRCA1 mutation, But this did not occur in those with a BRCA2 mutation.
article_snippet.sent: For the 70 BRCA1 carriers who had the 70 BRCA1 carriers who had their ovaries ovaries removed within two years, there was a 73 per cent reduction in death compared with women with the mutation who never underwent the procedure.
article_snippet.sent: Dr Steven Narod, of the Women’s College Research Institute, Toronto added that more research was needed, especially on carriers of the BRCA2 variant.
article_snippet.sent: Journal editor Dr Mary Disis said the results were ‘compelling and suggest the potential of oophorectomy should become part of the treatment discussion at the time of diagnosis for BRCA mutation carriers with early stage breast cancers’.
article_snippet.sent: Journal editor Dr Mary Disis added: ‘the results provide a validation of oophorectomy in coveying both a disease-free and overall survival benefit for BRCA1 carriers.
article_snippet.sent: Those women diagnosed with the BRCA1 gene mutation have a 50 to 80 per cent risk of developing breast cancer, pictured, in Those women lifetime .
article_snippet.sent: Women who inherit the faulty, or mutated, BRCA1 or BRCA2
article_snippet.sent: Genetic tests are available to women who are likely to have a BRCA1 or BRCA2 mutation, or faults in two other genes called TP53 and PTEN.
article_snippet.sent: BRCA gene faults are more common in the Ashkenazi Jewish population, about 2.3 per cent of Ashkenazi Jewish women have a BRCA gene mutation.
article_snippet.sent: Other studies of the gene mutation carriers have found that reduced mortality is associated with ovary removal for women with a history of breast cancer.
highlights_snippet.sent: Carriers of BRCA1 gene mutation who are diagnosed with breast cancer are less likely to die if Carriers of BRCA1 gene mutation who are diagnosed with breast cancer have Carriers of BRCA1 gene mutation who are diagnosed with breast cancer ovaries removed, study found .
  
highlights_snippet.sent: But the theory does not apply for those with BRCA2 gene mutation .
  
highlights_snippet.sent: Having the BRCA1 or BRCA2 genes increase risk of breast cancer by 70% .
  