article_snippet.sent: The early stages of the disease bring changes that may be so subtle that some friends and acquaintances are unaware that there is anything wrong - and this stage can continue for many years.
article_snippet.sent: But as the disease progresses and more damage is done to the brain, symptoms become more pronounced: difficulties with communication become more intense and issues such as getting dressed or managing day-to-day affairs become more problematic.
article_snippet.sent: This marks the beginning of the middle stage, the longest stage, which can last for several years.
article_snippet.sent: This's when the condition becomes more challenging and extra help may be needed.
article_snippet.sent: It can occur at any stage of the condition, but tends to peak at the middle stage and lessen as the disease progresses.
article_snippet.sent: The patient may struggle with nuances and may lose The patient sense of humour; The patient may also get frustrated and cross when The patient can't quickly bring to mind the words
article_snippet.sent: Furthermore, The patient may seem to get stuck in a loop and repeat the same question again and again.
article_snippet.sent: ■ Dr Souter is a retired GP and fellow of the Royal College of General Practitioners.