article_snippet.sent: Scientists found that the anti-fungal agent miconazole and the steroid clobetasol both restored movement to mice paralysed by a rodent version of multiple sclerosis (MS).
article_snippet.sent: This truly represents a paradigm shift in how we think about restoring function to multiple sclerosis patients.'
article_snippet.sent: Lead scientist Professor Paul Tesar, from Case Western Reserve School of Medicine, said: 'Lead scientist Professor Paul Tesar, from Case Western Reserve School of Medicine appreciate that some patients or their families feel some patients or their families cannot wait for the development of specific approved medications, but off-label use of the current forms of these drugs is more likely to increase other health concerns than alleviate multiple sclerosis symptoms. '
article_snippet.sent: Multiple Sclerosis Trust .
article_snippet.sent: We know that there are stem cells throughout the adult nervous system that are capable of repairing the damage caused by multiple sclerosis, but until now, We had no way to direct multiple sclerosis to act,' said Prof Tesar.
article_snippet.sent: We approach was to find drugs that could catalyse the body's own stem cells to replace the cells lost in multiple sclerosis.'
article_snippet.sent: As well as testing the drugs on mice affected by MS, the scientists also observed the scientists effect on human OPCs in the laboratory.
article_snippet.sent: The response was similar to that seen in mouse cells, with miconazole exerting the most potent effect.
article_snippet.sent: The data appear to suggest that these drugs can to some extent limit disability in experimental models of MS, though there is clearly much more to be optimised in this area, not least as the models tried thus far do not really look at effects on chronic demyelination. '
article_snippet.sent: However, particularly for patients with progressive MS - where it can be difficult to know how to impact the ongoing deterioration, these approaches offer the great advantage that these are tried, tested and safe drugs passed for use in humans. '
highlights_snippet.sent: Active ingredients in creams were found to cure multiple sclerosis (MS)
  Active ingredients in creams prompted stem cells to reverse the nerve damage caused by MS .
  