thoracoscopic needle aspiration biopsy has the greatest utility for the diagnosis of peripheral solitary pulmonary nodules ( spns ) that are suspected of being lung cancer . however , for centrally - located spns adjacent to major vessels , open thoracotomy is usually performed to obtain pathologic specimens . the authors report the technique of thoracoscopic needle aspiration biopsy for a centrally - located spn . chest computed tomography ( ct ) scans showed an spn 2.5 cm in size in just the medial aspect of the truncus anterior pulmonary artery and right upper lobe bronchus with no evidence of lymph node enlargement in the mediastinum ( fig . a double - lumen endotracheal tube was inserted under general anesthesia , and the patient was placed in the right lateral position . a 5-mm thoracoscopic port was made at the 6th intercostal space on the mid - axillary line and two 5-mm ports for thoracoscopic forceps and the aspiration needle were made at the 5th intercostal space on the anterior and posterior axillary lines . after a nodule was localized by palpation with the thoracoscopic forceps , a tumor biopsy specimen was obtained using a 5-mm endobiopsy aspiration cannula ( wisap , munchen , germany ) ( fig . 2 ) . the specimen was giemsa - stained and examined cytologically , and within 30 minutes the pathologic report revealed adenocarcinoma . right upper lobectomy with mediastinal lymph node dissection was performed through video - assisted thoracoscopic surgery on the spot . in this case , the patient complained of intermittent blood tinged - sputum of 2 weeks duration , but bronchoscopy failed to reveal the lesion and percutaneous needle aspiration could not be done due to its location . the patient was discharged uneventfully on the eighth postoperative day . during 3 months of follow - up the diagnosis of spn is one of the most common problems encountered by physicians treating diseases of the chest . . however , spns with shapes resembling carcinoma and arising in patients with a smoking history are highly likely to be lung cancer and require an urgent definitive diagnosis . larger central lesions lend themselves to bronchoscopic sampling , whereas smaller , peripheral lesions are commonly approached by percutaneous fine - needle aspiration under radiographic guidance . percutaneous needle aspiration has a relatively low sensitivity versus thoracoscopic lung biopsy and it is not helpful at avoiding open lung biopsy because a negative result does not guarantee benignity . thoracoscopic needle aspiration is a procedure intermediate between thoracoscopic lung biopsy and percutaneous needle biopsy . it can save surgical time , reduce costs , yields more information to pathologist compared with thoracoscopic lung biopsy . these advantages have encouraged the use of thoracoscopic needle aspiration for the rapid diagnosis of indeterminate peripheral spns . in cases of a centrally - located spn with a pathology not revealed by bronchoscopy and located too close to major vessels or structures to obtain a specimen by percutaneous needle aspiration or thoracoscopic or open lung biopsy , needle aspiration through exploratory thoracotomy provides a means of confirming pathology . thoracoscopic needle aspiration biopsy allowed us to acquire enough tissue for frozen biopsy during the operation because it uses a large bore needle . therefore , immediate diagnosis and further procedures are possible without waiting for days for permanent pathology . in addition , there is less risk of postoperative air leakage and bleeding , unlike thoracoscopic incisional biopsy . having achieved an advanced level of thoracoscopic surgical skill , a surgeon can directly palpate and control lesions with thoracoscopic instruments and can easily perform multiple aspirations of suspect nodules under clear vision . with a non - palpable spn , anatomic localization of the spn can be corroborated by careful preoperative ct imaging , and intraoperative instrumental palpation enables further localization . even if the aspiration needle punctures the wrong place such as a pulmonary artery , bleeding is easy to control by compression . therefore , thoracoscopic needle aspiration biopsy can be used in selective cases of non - palpable spn . in conclusion , the authors successfully attempted thoracoscopic needle aspiration for a central lesion . compared with exploratory thoracotomy , this procedure facilitates neoadjuvant chemotherapy , saves surgical time , and reduces the length of stay and postoperative pain . in the absence of severe pleural adhesion , thoracoscopic needle aspiration is a good alternative for centrally - located spns suspected of being lung cancer .
thoracoscopic needle aspiration is a good alternative for a centrally - located solitary pulmonary nodule ( spn ) suspected of being lung cancer without severe pleural adhesion . 
 the authors report the technique of thoracoscopic needle aspiration biopsy in a spn just in the medial aspect of the truncus anterior pulmonary artery and the right upper lobe bronchus .