the term osteosarcoma refers to a heterogenous group of primary malignant neoplasms affecting bone forming or mesenchymal tissues that have histopathologic evidence of osteogenic differentiation.1 osteosarcoma is a highly malignant bone tumor2 and it is relatively a rare disease in the head and neck region.3 it occurs infrequently in the jaws , as some series have revealed that approximately only 8% of all osteosarcomas develop in this location.2 osteosarcomas and chondrosarcomas of the jaws exhibit some behavioral features that separate them from the lesions of the rest of the skeleton . jaw lesions tend to occur at an older mean age ( fourth decade versus second decade for non jaw lesions).4 pain and swelling are more typical of jaw lesions.4 metastasis is less likely2,4 and prognosis is correspondingly more favorable : approximately 40% 5-year survival rate versus 20% for non jaw lesions.4 although in the jaws conventional osteosarcomas involving the mandible and maxilla display a predilection for males,2,4,5,68 some studies display slight predilection for females.9,10 there is a nearly equal involvement of the maxilla and the mandible.2,5,6 bennett et al9 stated that mandibular tumors were predominant in females . in contrast , forteza et al10 stated that the maxillary tumors were predominant in females . in addition , most maxillary lesions were found osteoblastic and mandibular lesions were found osteolytic . the majority of mandibular osteosarcomas arise in the body of the mandible ; the remaining sites of the predilection include the symphisis , angle of the mandible , ascending ramus and temporomandibular joint . in the maxilla , there is a nearly equal incidence of tumors involving the alveolar ridge and maxillary antrum , with a few affecting the palate.5 maxillary tumors may extend to the infratemporal fossa and to maxillary sinus and attain a greater volume before diagnosis.6 in differential diagnosis of osteosarcoma , fibrous dysplasia and osteomyelitis must be taken into consideration.11 in this article , we want to emphasize the importance of dentists on diagnosis and prognosis of oral malignancies with presenting an osteosarcoma case . a fifty year - old woman referred to selcuk university , faculty of dentistry , oral diagnosis and radiology department clinic with a chief complaint of a remaining root and pain which had been lasting for two months after a tooth extraction from right maxillary posterior region . she stated that she had her teeth extracted because of a long lasting pain , but until that time her pain had not relieved . intra oral examination revealed a 2 cm sized , fibrotic , non bleeding mass coinciding with a dense expansion in bone ( figure 1 ) . although mucositis areas were found owing to occlusal trauma , there was no ulceration on the surface of the lesion . on the panoramic radiography ( figure 2 ) , the lesion was seen as extending to tuber maxilla distally and to maxillary sinus coronally . the inferior border of the maxillary sinus could nt clearly be followed on distal side . the radiographic dimensions of the lesion were approximately 4x3 cm and the borders were ill - defined . sun - burst appearance  , which is one of the characteristic properties of malign lesions , could easily be seen . on the left side , the lesion was thought as malignant because of the radiological findings , clinical appearance and the history of the patient . but in the view of clinical and radiological features of the case , calcifying fibroma result seemed to be unharmonious . our case is in agreement with the literature on age , pain , swelling,4 gender,9,10 tumor type10 and location,5,6 presenting signs of the disease.4 also the tumor extended to maxillary sinus before being diagnosed . histopathologic appearances of osteosarcoma , osteomyelitis and fibrous dysplasia occupy a spectrum that may have considerable overlap . in some cases , a classic histopathologic appearance makes the diagnosis clear ; however , when the picture is that of new bone formation in a back - ground of cellular fibrous connective tissue , the diagnosis is more difficult . depending on tissue sampling and location of biopsy , these same features could occur in well - differentiated ( fibroblastic ) osteosarcoma , active fibrous dysplasia and chronic osteomyelitis . in making diagnosis the radiographic characteristics can play a more significant role especially when histopathology is not clear - cut and classic.11 the overlapped radiographic characteristics of these lesions are : all of them frequently occur in the posterior body of the mandible . the periphery may be ill defined and they can all cause enlargement . this may result in a spiculated pattern of new bone formation in association with a soft tissue mass peripheral to outer cortical boundary of the involved bone.11 this finding was also seen in our case . fibrous dysplasia can cause expansion of the involved bone but maintain a thinned , intact cortical boundary . fibrous dysplasia can alter the appearance of lamina dura but the periodontal ligament space is not widened.11 fibrous dysplasia has different radiographic patterns such as ground - glass , orange peel and cotton wool.12 also because fibrous dysplasia is usually found in more younger age group than osteosarcoma , in our tentative diagnosis it was excluded . osteomyelitis shows the presence of sequestra and laminated periosteal reactive bone formation usually.11 no infection finding was found in our case . computed tomography has come to play a large role in the interpretation of osseous changes in the jaws.13 but the diagnosis of dentists are especially confined to plain films . the panoramic radiography is commonly used in dental practice as well as periapical and occlusal radiography and is well interpreted by general practitioners and dental specialists . thorough radiological examination and recognition of the radiological features of osteogenic sarcoma can lead to a prompt diagnosis . this will lead to earlier referral of patients for definitive diagnosis and may prevent needless tooth extraction , which facilitates the spread of the tumour.8 the teeth of patients with osteosarcoma may displace or be lost.2 but there are different causes of tooth loss such as periodontal and endodontic ones.14 radiographic evaluation is important in diagnosis , because clinical symptoms , such as pain , paresthesia , swelling and loosening of teeth are not specific.10 better knowledge and understanding of the radiological features of can lead to an earlier diagnosis , shorten any delay and so improve the prognosis.8 the teeth of our patient were extracted because of insufficient evaluation the condition . therefore early diagnosis may improve the patients life and obtain to live them with minimal defects . however , as in our case , the operation of the tumoral tissue will be difficult due to the proximity of important anatomical structures . in addition consequently , knowing the radiological and clinical properties of malignant lesions will provide the determination of biopsy necessity and type . in the first biopsy , , it can be said that in the lesions which extended from central to peripheral tissues and affected the soft tissues , biopsy specimen should be taken not only from soft tissue but also from bone . petrikowski et al11 compared the osteosarcoma , fibrous dysplasia and osteomyelitis . in the majority of their osteosarcoma cases they saw spiculations . they concluded that a periosteal response consisting of spiculations perpendicular to the periosteum is often associated with malignant bone disease although it is not a consistent finding particularly early in lesion maturation when periosteal involvement has not yet occurred.11 in our case the superficial specimen that included perhaps immatured part of the lesion caused the pathologist to decide to define the lesion as calcifying fibroma . such a team might consist of a dental hygienist , dentist , dental specialist , oncologists , nutritionist , psychiatrist or psychologist and social worker . the dental community has a responsibility for education , early detection , diagnosis and referral of cancer to confreres competent in the treatment of oral cancer.15 the patients firstly prefer to go to the dentists when they have an orofacial pain . so the dentists are important in the diagnosis of not only oral but also maxillofacial lesions and they should be able to distinguish lesions especially malign ones by combining clinical and radiological findings .
although osteosarcoma of the head and neck is a relatively rare disease , it is a highly malignant bone tumor . 
 diagnosis of the tumor is important especially in early stages for improving prognosis . 
 the patients with orofacial pain firstly prefer to go to dentists . 
 such kind of pain may be associated with an oral or maxillofacial cancer . 
 the dentists must be careful for evaluating the clinical and radiologic clues . 
 these clues determine the biopsy necessity , type and management plan . 
 the aim of this case presentation is to emphasize the importance of dentists on diagnosis and prognosis of oral malignancies .