in anti - aging medicine , as in various specialties of medicine , the symptoms of disease and disability often reflect the consequences of attempts of the nervous system to adapt to an insult by remodeling synaptic plasticity , which often results in adaptive responses that are not positive for health.13 the consequent adaptive responses may also be maladaptive,4 which can contribute to functional disability affecting motor control and posture . it is well known that psychological factors may manifest physically as psychogenic movement disorders,59 which may also have consequences at both the muscle and joint levels.1015 this emotional component of movement disorders is often the basis for joint problems that occur in aging , and can be linked to inadequate coping reactions16,17 and environmental stress.1820 the psychological component is often unknown to both the patient and the medical team , and therefore can be responsible for the limited effectiveness of physiotherapy . recent work has focused on the development of various techniques for brain stimulation that can be used to improve motor and cognitive functions.2124 coxarthrosis is a disease affecting the hips . one treatment is classical physiotherapy with local hyperthermia , and another is radioelectric asymmetric brain stimulation ( reac ) , which aims to enhance motor and cognitive function . we investigated the use of these two techniques for the treatment of pain and functional impairment in elderly patients with coxarthrosis . this randomized retrospective study analyzed data in the medical records of two groups of patients with coxarthrosis attending two different clinics for rehabilitation therapy . the data were collected by a researcher who was not involved in the analysis or interpretation of the study data . information recorded included the age , duration of symptoms , severity , and sociocultural background of each patient , which were matched between the treatment groups . each patient was ranked by the kellgren - lawrence classification for arthrosis , as follows : 0 = normal , 1 = questionable diagnosis , 2 = incipient or mild arthrosis ( slight narrowing of the joint space ) , 3 = moderate arthrosis ( distinct narrowing of the joint , bone cysts and sclerosis ) and 4 = severe arthrosis ( severe structural disorder of the joint ) . group a included 15 patients ( 10 females and five males , mean age , 61.46  7.57 years ) suffering from coxarthrosis ( kellgren - lawrence classification grade 2 [ n = 7 ] and grade 3 [ n = 8 ] ) and treated in a physiotherapy clinic . group b included 15 patients ( 13 females and 2 males , mean age , 69.33  9.85 years , kellgren - lawrence classification grade 2 [ n = 8 ] and grade 3 [ n = 7 ] ) who were treated in a clinic for stress - related disorders . despite the difference in mean age between the treatment groups , the preliminary ( t0 ) and the final ( t1 ) clinical evaluation of patients was performed by different physiatrists and orthopedic specialists for each clinic . physiatrists and orthopedic specialists , although belonging to different clinical disciplines , had similar professional skills . range of motion in terms of active flexion of the hip , and knee flexion and extension ( figures 1 and 2 ) , was measured using a goniometer and muscle bulk with a tape measure . group b received a course of reac in an attempt to improve their motor skills . the hyperthermia device25 ( easytech , bari , italy ) is used in the field of endogenous thermotherapy . the device is capable of delivering endogenous heat using electromagnetic fields at 433.92 mhz or delivering exogenous heat using a thermostatically controlled heated water bolus . each treatment session , using a water bolus warmed to 37.5c by 65 w of power , lasted for 30 minutes . the reac is an innovative biostimulation medical device ( convogliatore di radianza modulante , asmed , italy).26,27 reac therapy has been shown to be efficacious in ameliorating motor behavior abnormalities,28 stress - related disorders , depression , anxiety,2934 and bipolar disorders.35 it works through a typical range of frequencies of 2.4 , 5.8 , or 10.5 ghz , as selected by the operator for each specific protocol used . a frequency of 10.5 ghz was used for the brain stimulation protocols in this study . the radioelectric parameters were as follows : radiated power , approximately 2 mw ; electric field , e = 0.1 v / m ; magnetic field , 0.23 ma / m ; and specific absorption rate , 7 w / kg . a sequence of seven radiofrequency pulses of 500 msec , called neuropsychophysical optimization , was applied by touching the metallic tip of the reac probe onto seven reflex auricular points . this protocol , consisting of 18 sessions administered on alternate days , is always preceded by a preparatory session , called neuropostural optimization.28 this protocol , which consists of a 500 msec single pulse in a specific area of the ear located at the top of the lower third of the scapha , was specifically designed for the reorganization of neuromuscular control . statistical analysis was performed using the wilcoxon signed - ranks test and sign - test for comparative groups . we used spss release 13 ( spss inc , chicago , il ) for data analysis . group a included 15 patients ( 10 females and five males , mean age , 61.46  7.57 years ) suffering from coxarthrosis ( kellgren - lawrence classification grade 2 [ n = 7 ] and grade 3 [ n = 8 ] ) and treated in a physiotherapy clinic . group b included 15 patients ( 13 females and 2 males , mean age , 69.33  9.85 years , kellgren - lawrence classification grade 2 [ n = 8 ] and grade 3 [ n = 7 ] ) who were treated in a clinic for stress - related disorders . despite the difference in mean age between the treatment groups , the clinical picture was similar ( table 1 ) . in both groups the preliminary ( t0 ) and the final ( t1 ) clinical evaluation of patients was performed by different physiatrists and orthopedic specialists for each clinic . physiatrists and orthopedic specialists , although belonging to different clinical disciplines , had similar professional skills . range of motion in terms of active flexion of the hip , and knee flexion and extension ( figures 1 and 2 ) , was measured using a goniometer and muscle bulk with a tape measure . group b received a course of reac in an attempt to improve their motor skills . the hyperthermia device25 ( easytech , bari , italy ) is used in the field of endogenous thermotherapy . the device is capable of delivering endogenous heat using electromagnetic fields at 433.92 mhz or delivering exogenous heat using a thermostatically controlled heated water bolus . each treatment session , using a water bolus warmed to 37.5c by 65 w of power , lasted for 30 minutes . the reac is an innovative biostimulation medical device ( convogliatore di radianza modulante , asmed , italy).26,27 reac therapy has been shown to be efficacious in ameliorating motor behavior abnormalities,28 stress - related disorders , depression , anxiety,2934 and bipolar disorders.35 it works through a typical range of frequencies of 2.4 , 5.8 , or 10.5 ghz , as selected by the operator for each specific protocol used . a frequency of 10.5 ghz was used for the brain stimulation protocols in this study . the radioelectric parameters were as follows : radiated power , approximately 2 mw ; electric field , e = 0.1 v / m ; magnetic field , 0.23 ma / m ; and specific absorption rate , 7 w / kg . a sequence of seven radiofrequency pulses of 500 msec , called neuropsychophysical optimization , was applied by touching the metallic tip of the reac probe onto seven reflex auricular points . this protocol , consisting of 18 sessions administered on alternate days , is always preceded by a preparatory session , called neuropostural optimization.28 this protocol , which consists of a 500 msec single pulse in a specific area of the ear located at the top of the lower third of the scapha , was specifically designed for the reorganization of neuromuscular control . statistical analysis was performed using the wilcoxon signed - ranks test and sign - test for comparative groups . we used spss release 13 ( spss inc , chicago , il ) for data analysis . the patients in group a showed a significant decrease in pain and stiffness , but no significant improvement in joint range of motion or muscle bulk . the condition of one patient in group a worsened , and the pain did not completely disappear in any patient . one month after the end of treatment at t1 , visual analog scores ranged from 7 to 1 ( mean , 2.73 , see table 2 ) . at t0 , the range of active flexion of the hip with the knee flexed ranged from 80 to 100 ( mean , 86 ) and showed no change after 1 month of treatment ( 80100 , mean , 86.7 , table 3 ) . active flexion of the hip with the knee extended ranged from 60 to 80 pretreatment at t0 ( mean 72.7 ) , which changed to 7080 ( mean 75.3 ) after 1 month of treatment ( see table 4 ) . patients in group b experienced a significant decrease in symptoms of pain and stiffness , and significant improvements in range of movement and bulk . the initial visual analog scores at t0 ranged from 4 to 8 ( mean 6.0 ) , but improved to 03 ( mean 1.47 ) after 1 month of treatment . at baseline in group b , active flexion of the hip with the knee flexed ranged from 70 to 100 ( mean 87.3 ) , which improved to 90120 ( mean 101.3 ) 1 month after treatment ( table 3 ) . active flexion of the hip with the knee extended improved from 60 to 80 pretreatment ( mean 72.7 ) to 70 to 90 ( mean 84.0 ) following treatment . statistical analysis showed that the change in group b was statistically significant compared with group a ( table 5 ) . the only side effect found was in the reac group , in which some patients experienced a transient increase in pain during sessions 610 , although the functional capacity of their hip joints continued to improve over this period . it is well known that the therapeutic response may be different in different subjects after the same treatment is applied , which may be due in part to a psychogenic behavioral component.3638 this can often be difficult to recognize by both the therapist and the patient . the results of our study show that physiotherapy with local hyperthermia is effective , but less so than treatment with reac to improve motor skills . physiotherapy aims to reduce symptoms without addressing the underlying cause , and does little to address the aberrant motor behavior caused by neuropsychophysical responses to environmental stresses.1,2 it is likely that the reac brain stimulation protocol achieves a better response in those areas of the brain responsible for controlling mood and motor behavior,3943 which can be altered at a young age44 and predispose to physical manifestations in adults . these aspects are particularly important in the elderly , in whom functional limitation is often associated with or exacerbated by a psychogenic component . we suggest that further investigation is warranted to determine the usefulness of reac as a supplementary treatment for elderly patients with coxarthrosis .
background : it is well known that psychological components are very important in the aging process and may also manifest in psychogenic movement disorders , such as coxarthrosis . 
 this study analyzed the medical records of two similar groups of patients with coxarthrosis ( n = 15 in each ) who were treated in two different clinics for rehabilitation therapy.methods:patients in group a were treated with a course of traditional physiotherapy , including sessions of local hyperthermia . 
 group b patients were treated with only a course of radioelectric asymmetrical brain stimulation ( reac ) to improve their motor behavior.results:group a showed a significant decrease in symptoms of pain and stiffness , and an insignificant improvement in range of motion and muscle bulk . 
 a single patient in this group developed worsened symptoms , and pain did not resolve completely in any patient . 
 the patients in group b had significantly decreased levels of pain and stiffness , and a significant improvement in range of motion and muscle bulk . 
 no patients worsened in group b , and the pain resolved completely in one patient.conclusion:both treatments were shown to be tolerable and safe . 
 patients who underwent reac treatment appeared to have slightly better outcomes , with an appreciable improvement in both their physical and mental states . 
 these aspects are particularly important in the elderly , in whom functional limitation is often associated with or exacerbated by a psychogenic component .