group i : normal saline ( 0.5 ml ) , group ii : tramadol ( 10 mg / kg bw ) , group iii : atorvastatin ( 10 mg / kg bw ) and group iv : simvastatin ( 10 mg / kg bw ) . the tests conducted were tail clip method , eddys hot plate and hot water tail immersion method . atorvastatin and simvastatin differ significantly from control hence they have analgesic action and even at any of the time intervals they do not differ significantly from tramadol ; hence their analgesic effect is nearly comparable to tramadol . the results of the present study indicate that atorvastatin and simvastatin have analgesic action . these statins are found to have analgesic effect other than hypolipidemic activity and can be used in these patients .
objectives:1 ) to evaluate the analgesic effect of atorvastatin and simvastatin . 
 2 ) to compare analgesic activity of these with an established drug tramadol.materials and methods : healthy albino rats were taken . 
 they were randomly divided into 4 groups of six animals each . 
 group i : normal saline ( 0.5 ml ) , group ii : tramadol ( 10 mg / kg bw ) , group iii : atorvastatin ( 10 mg / kg bw ) and group iv : simvastatin ( 10 mg / kg bw ) . 
 the animals were subjected to 3 different tests at different interval of time . 
 the tests conducted were tail clip method , eddys hot plate and hot water tail immersion method.results:atorvastatin and simvastatin differ significantly from control hence they have analgesic action and even at any of the time intervals they do not differ significantly from tramadol ; hence their analgesic effect is nearly comparable to tramadol . 
 the results of the present study indicate that atorvastatin and simvastatin have analgesic action.conclusion:these statins are found to have analgesic effect other than hypolipidemic activity and can be used in these patients 
 . however further study has to be undertaken in a broader way .