intraoperative tee ( itee ) was introduced in cardiac anesthesia in the late 1980s in the usa where it was primarily considered to be a tool for monitoring the left ventricle . it soon became clear that itee could give more information than just the state of the left ventricle .   in the last 10 years the use of itee has expanded enormously and is now recognized as an excellent intraoperative diagnostic tool . in selected patient groups , itee has been shown to be beneficial in cardiac surgery improving cardiac outcome ; it often provides new and important information about pathophysiology and may guide both surgical and anesthetic therapy . although itee is routinely used during mitral valve repair ( mvr ) , the impact of itee among patients undergoing coronary artery bypass grafting ( cabg ) is less well documented . all patients studied with itee should have a full and comprehensive examination of the heart during cardiac surgery . the purpose of the present study was to evaluate the impact of itee on surgical decisions - making in a group of patients undergoing on pump cabg , with reference to the mitral and aortic valve and the need for mv repair or mv replacement or av replacement at the time of myocardial revascularization , and to other associated cardiac defects requiring surgical intervention . between january 2008 and december 2008 we prospectively studied the perioperative course of all adults who underwent elective on - pump cabg of three cardiovascular surgeons in which itee examination was performed . after the study approval from the ethics committee , written informed consent was obtained from each patient . patients were excluded from the study if they had complex congenital heart disease or prior cardiac surgery and if valve surgery was already planned . clinical variables , hemodynamic and coronarographic studies , surgical and pathologic reports , and intraoperative echocardiographic reports were reviewed . experienced cardiologists performed preoperative tte examinations in all patients scheduled for cabg by using ie33 echocardiography system ( philips , amsterdam , the netherlands ) at last one month before surgery . standard views and measurements were obtained in order to perform a complete preoperative evaluation .   according to our study protocol , itee was performed 30 minutes after induction of general anesthesia in all patients included in this study . a complete exam was obtained in each patient according to ase / sca guidelines . in order to confirm preoperative diagnosis , left ventricular wall motion abnormalities images were obtained before and after bypass , after the hemodynamics had been stabilized . all itee examinations were performed by 2 of 7 cardiac anesthesiologists , each with at least 3 years of itee experience , with the use of ie33 echocardiography system ( philips , amsterdam , the netherlands ) with an omniplane probe . aortic valve defects were assessed with 2d evaluation of aortic valve anatomy and planimetry on short axis view ( transverse plane at 40 ) and long axis view ( longitudinal plane at 120 ) , and with spectral doppler interrogation of transvalvular flow in deep transgastric aortic valve view . we quantified the severity of the stenotic lesion with doppler echocardiographic measurements of maximum jet velocity , mean transvalvular pressure gradient , and continuity equation valve area , as suggested by the acc / aha / ase 2003 guidelines for the clinical application of echocardiography    and we defined aortic stenosis as : mild ( area > 1.5 cm , mean gradient < 25 mm hg , or jet velocity < than 3.0 m / sec ) , moderate ( area between 1.0 and 1.5 cm , mean gradient between 25 and 40 mmhg , or jet velocity between 3.0 and 4.0 m / sec ) , or severe ( area < than 1.0 cm , mean gradient > 40 mmhg , or jet velocity greater than 4.0 m sec ) .   in patients with aortic regurgitation ( ar ) , we evaluated the severity of ar with colour doppler to measure the vena contracta and with cw doppler to calculate pressure half time ( pht ) and deceleration rate ( dr ) in addition to evaluation of lv cavity dilatation . we defined ar as : mild ( vena contracta < 5 mm , pht > 500 msec , dr < 200 cm / sec ) , moderate ( vena contracta between 5 - 7 mm , pht between 350 - 500 msec , dr between 250 - 300 cm / sec ) , or severe ( vena contracta > 7 , pht < 200 msec , dr > 300 cm / sec ) .   the severity of mitral regurgitation ( mr ) was determined by composite analysis of qualitative color flow doppler imaging , pulmonary vein inflow by pulsed - wave doppler , and vena contracta method quantification . we defined mr as : mild ( vena contracta <3 mm ; jet area <3 cm , normal pulmonary vein flow pattern ) , moderate ( vena contracta between 3 - 6.9 mm ; jet area between 3 - 6 cm , blunt pulmonary vein flow pattern ) , or severe ( vena contracta > 7 mm ; jet area > 6 cm , reversed pulmonary vein flow pattern ) . the interatrial septum was visualized from the midesophageal level longitudinal view in order to identify a patent foramen ovale ( pfo ) . a pfo was diagnosed if contrast material ( air bubbles ) was seen in the la after release of positive airway pressure or if a left - to - right shunt was clearly identified by color doppler mapping in the region of the fossa ovalis . based on echo findings , the surgical planning of patients scheduled for cabg , in whom a valve dysfunction or other heart abnormality was detected by itee as a new finding , was changed following the recommendations by aha / acc published in 1998   and revised in august 2006 . between january and december 2008 , there were 537 patients who underwent cabg , all of whom had itee . sixteen patients were excluded based on the exclusion criteria . the new york heart association ( nyha ) functional classification of the study pa - tients showed that the majority of patients ( 58% ) were preoperative nyha fun - ctional class i ; 36% of patients were in nyha functional class ii and 6% of pa - tients were nyha functional class greater than class ii . the mean ejection fraction ( ef ) was 38%8.2 as seen in table 1 . new information was obtained in 82 ( 15.7% ) pa - tients before the cardiopulmonary bypass . in 62 ( 11.9% ) of these patients , of the 521 patients undergoing cabg , 28 ( 5.3% ) patients with negative preo - perative tte , mv surgery had not been planned preoperatively but was per - formed after detecting at least moderate mr or a significant structural mv ab - normality by itee . table 2 outlines the mr severity , pathology , and surgical procedures in these 28 patients . itee findings in 28 patients who underwent mv surgery in whom mv surgery was not planned before the operation . there were 6 patients who had mv surgery planned at the time of cabg , but mv surgery was cancelled on the basis of the itee finding of less severe mr than was previously detected prior to surgery and/or adequate functional struc - tures of the mv . in 8 ( 1.5% ) patients a severe aortic valve stenosis was found that required avr .   in 2 ( 0.38% ) cases aortic valve insufficiency was found : one case showing se - vere ar underwent avr ; the other case with moderate ar underwent avr be - cause of reduced lv function ( ef<50% ) .   in 21 ( 4% ) patients a pfo was found and 15 patients ( 2.8% ) underwent closure of patent foramen ovale .   in 3 cases ( 0.57% ) a small ( 3 - 4 mm diameter ) , mobile mass on the aortic side of the cusps of the aortic valve was detected , and needed resection . in all cases histology results from the resected cusp confirmed fibroelastoma .   in 14 patients tee suggested that cardioplegia be performed selectively due to mild - moderate aortic valve regurgitation . new postbypass findings were obtained in 8 patients ( 1.5% ) and the surgical plan was altered in 4 patients ( 0.7% ) .    in particular there were 7 patients who had a new wall motion abnormality ( rwma ) ; a graft flow evaluation was done without alter the surgical plan . in 3 cases a mr was detected after a mv posterior pericardial annuloplasty , and a posterior commissural resuturing was again performed on - pump . in our experience , a primary and common indication for itee is patients under - going cabg . itee was initially used in these cases to assess the wall motion abnormalities before and after cardiopulmonary bypass . it has since become important in assessing other cardiac abnormalities in patients undergoing cabg and has potential for use in concomitant mv or other cardiac surgery . the analysis of functional morphology of the mv generally permits identification of a primary defect in mv coaptation that may produce significant mr that will not improve even after successful revascularization of abnormally moving myocardium . in such cases , conversely , ischemic mr in the setting of severe coronary artery disease with otherwise structurally normal mv anatomy requires careful evaluation of left ventricular geometry and its impact on mv apparatus deformation .    also , deep evaluation of the aortic valve is important in cad patients .   aortic valve pathology is often associated with coronary artery disease . it is very important to consider the increased risk of reintervention after cabg in order to correct an aortic valve defect . this risk is probably higher than the risk associated with prolonging the pump during the same procedure . we found 82 ( 15.7% ) new prebypass findings in a study population of 521 pa - tients . the new findings resulted in a change in the surgical decision - making plan of 62 patients ( 11.9% ) . new postbypass findings were obtained in 8 patients ( 1.5% ) and the surgical plan was altered in 4 patients ( 0.7% ) . new findings ( pre and postbypass ) were obtained in 90 patients ( 17.2% ) and the surgical plan was altered in 66 patients ( 12.6% ) . the most common new finding was pfo in 21 patients that was closed in 15 patients . the reason for closure of the pfo was based on our policy to prevent potential postoperative hypoxia under mechanical ventilation , according which large pfo , or situations such as pulmonary hypertension , elevated cvp , right ventricular dysfunction require closure of pfo in patients undergoing cardiac surgical procedures .    in 28 ( 5.3% ) patients , unplanned mv surgery was added to cabg based on the intraoperative echo findings . in addition , there were 6 ( 1.1% ) patients whose mv surgery was cancelled ba - sed on the tee . our study specifically reports the utility of itee in the evaluation of cardiac structures during cabg procedures . the impact of itee has been established in a number of settings but primarily in mv repair . with additional experience , the utility and impact of tee in the setting of other cardiac surgical procedures has become apparent . studies have documented the impact of itee on valve surgery , with changes in the operative plan based on transesophageal echocardiography findings in 11% to 14% of cases . additionally , itee was found in the detection of problems with surgical procedure and subsequent need to return to cardiopul - monary bypass reported in 2% to 6% . one of the most recent from fatema et al . reported new findings ( pre - bypass and postbypass ) in 13% of patients undergoing elective cabg and the surgical plan was altered in 5.5% of patients . they support the use of itee in patients undergoing coronary artery bypass graft surgery . comparing his data with other studies , fatema et al . concluded that the overall impact of itee was lower than in studies that focused on high - risk patients . our results show almost the same incidence of new findings by itee , but they show a higher incidence of surgical intervention . we may speculate that some interventions were not necessary so the patients were at increased risk ; or we may speculated that the tte obtained before surgery , was not as accurate . there are several causes of possible hemodynamic disturbance in the operating room , such as anesthetic drugs , mechanical ventilation , surgical manipulations of the heart , some of which can dramatically affect left ventricu - lar loading and thus influence itee assessment . although we routinely optimize hemodynamics before echocardiography , such factors could not be controlled in this study .   quantitative analysis of mr severity was not performed in all patients in this study , allowing for subjective interpretation of mr severity in 2 cases . interpre - tation of mr severity by transthoracic versus transoesophageal echocardio - graphy can also be variable , particularly with technically difficult transthoracic imaging windows . such variability in assessment of mr could not be assessed in the current study . also we admit the lack of outcome data at this stage , although follow - up anal - ysis was not the goal of this study . itee plays an important role in surgical decision - making during cabg proce - dures . in our series , additional information that altered the surgical plan was found in 66 patients ( 12.6% ) undergoing cabg . while further studies should be performed to investigate on the impact of this issue on the patients outcome , these data support the routine use of itee in a unselected group of patients undergoing surgical myocardial revascularization : the impact of itee in surgical management was relevant so we do believe that itee must have a special place in cardiac surgery , and it should be used by experienced hands to correctly diagnose the pathophysiology of heart disease .
introductionintraoperative transesophageal echocardiography ( itee ) is widely accepted and routinely used during heart valve surgery . however , the impact of itee among patients undergoing coronary artery bypass grafting ( cabg ) is less well documented . in this study 
 , we aim to define the impact of itee in patients undergoing myocardial revascularization for severe coronary artery disease.methodswe analyzed clinical data and preoperative and intraoperative echocardiograms of all adults who underwent on pump coronary bypass and itee between january 2008 and december 2008.results521 patients ( mean age 6914 years ) were studied . 
 new prebypass findings were obtained in 82 ( 15.7% ) patients : in 62 ( 11.9% ) of these patients , this information changed the surgical plan . 
 new postbypass findings were obtained in 8 patients ( 1.5% ) and the surgical plan was altered in 4 patients ( 0.7%).conclusionsoverall new findings were obtained in 90 patients ( 17.2% ) and the surgical plan was altered in 66 patients ( 12.6% ) . 
 these data support the routine use of itee among patients undergoing surgical myocardial revascularization .