solitary plasmacytoma of bone ( spb ) is a rare localized lesion that accounts for only 4% of malignant plasma cell tumors.[13 ] it may present as the sole manifestation of plasma cell neoplasm , as a solitary plasmacytoma of the bone or as a consequence of multiple myeloma . a solitary plasmacytoma in a rib usually shows destruction of the bone cortex with extension into the surrounding soft tissues . plasmacytoma may be primary or secondary to the disseminated multiple myeloma and may arise from the osseous ( medullary ) or nonosseous ( extramedullary ) sites . a 43-old - nonsmoker female reported with pain in the chest on right side which was sudden in onset , mild - to - moderate in nature , nonradiating and increased on coughing since 2 months . fever was present off and on since one year . on local examination of the chest , chest x - ray showed a large extra pulmonary opacity with well defined medial margin and lateral margin merging with chest wall on right side . on contrast - enhanced computed tomography ( cect ) of the chest revealed a well defined hypodense soft tissue mass of size about 8.5 - 7.6 cm on right side of the chest wall with invasion of the fifth rib with adjoining parietal wall [ figure 2a  b ] . chest x - ray showing a large extra pulmonary opacity with well - defined medial margin and lateral margin merging with chest wall on right side ( a - b ) contrast -enhanced computed tomography of the chest revealed a well - defined hypodense soft tissue mass on right side abutting the chest wall with invasion of fifth rib and associated pleural effusion serum electrophoresis for m band proteins showed prominent m band . pleural fluid tapping was negative for tuberculosis or malignancy . on bone marrow biopsy there were no excess of plasma cells ( 2% ) . right posterolateral thoracotomy was done which revealed a well circumscribed tumor of 10  12 cm in size arising from the fifth rib anteriorly . en - bloc resection of fifth rib with involved parietal pleura and muscles was done with 5 cm , from the tumor margins . postoperative picture showing no recurrence [ figure 3 ] . in follow - up of two and half year , patient is doing well and asymptomatic . solitary plasmacytomas of bone are defined as clonal proliferations of plasma cells identical to those of plasma cell myeloma , which manifest a localized osseous growth . plasmacytomas can be divided into multiple , solitary osseous , and solitary extraosseous or extramedullary plasmacytomas and rare as compared with multiple myeloma . localized spb is a rare disease and is characterized by one or two isolated bone lesions with no evidence of disease dissemination and has been considered to be curable with radiotherapy and surgical resection . spb is an uncommon disease that accounts for only 5% of malignant plasma cell tumors and is less common in the chest wall than spine . the thoracic spine is most commonly involved followed by lumbar spine . in japanese 's literature , 14 cases of solitary plasmacytoma of rib origin have been described . the average age on presentation was 59.5 years with a range form 39 to 77 years . mendenhall et al , reported a 6% local failure rate in patients with solitary plasmacytoma treated with doses of 40 gy or above in contrast to 31% for doses below 40 gy . aviles et al , observed that most patients treated with adequate radiation therapy alone will develop multiple myeloma within the first 3 years after diagnosis and treatment . in our case , we had referred the patient for radiotherapy and then common decision was taken to go first for radical surgery . even according , to bataille and sany the primary methods for treating solitary plasmacytoma they showed the lowest incidence of progressive diseases in patients with peripheral solitary plasmacytoma who were treated with surgery plus an adequate dose of radiation therapy . the diagnosis is based on identification of the localized tumor composed of monoclonal plasma cells identical to those observed in multiple myeloma , and absence of the signs in favor of a disseminated form . according to the current recommendations , the detection of a monoclonal component in the serum or urine does not exclude a diagnosis of solitary plasmacytoma . urine electrophoresis is an important test , because it may show abnormalities in a few patients even when the serum electrophoresis is normal . spb is characterized by only one or two isolated bone lesions with no evidence of disease dissemination and has been considered to be curable with radiotherapy and surgical resection and such treatment is sufficient to achieve long - term survival . on the contrary , spb has been considered to be a genetic abnormality which could lead to the development of multiple myelomas . in our case , a patient with a chest wall tumor is reported in whom solitary plasmacytoma originating in the rib was surgically treated with radiation therapy followed by adjuvant chemotherapy . aviles et al . showed that the use of low doses of melphalan and prednisolone contributed to an improvement in disease - free survival and overall survival in patients with spb , compared with patients who were treated with radiotherapy alone . their results suggest that the use of adjuvant chemotherapy will improve the outcome and prolong the duration of remission and survival . in our case , we conclude that preoperative radiotherapy with complete en - block resection , followed by adjuvant chemotherapy , aided the long - term survival and disease - free of patient . in our case also , patient was free from disease for long term , by using same pattern of treatment as suggested by author kadokura et al . patients with solitary plasmacytoma originating in the rib have a feasibility of operative indication and radical treatment is expected to be by adequate surgical resection followed by chemotherapy .
localized solitary plasmacytoma of the bone is a rare disease and is characterized by only one or two isolated bone lesions with no evidence of disease dissemination . 
 we report a case of solitary plasmacytoma of the rib in a 43-year - old female . 
 the patient underwent complete en - bloc resection of the chest wall including rib , muscle , and parietal pleura . 
 patient is asymptomatic without any recurrence after two and half years of follow up .