endodermal cysts are presumed to be derived from the endoderm of the developing gastrointestinal tract or , in rare cases , the respiratory system . if the endodermal cyst is predominantly lined with respiratory tract epithelium , it is termed a bronchogenic cyst . intraspinal bronchogenic cysts are rare , and their site of predilection is the cervical or upper thoracic segments generally with an intradural extramedullary localization . we report a rare case of an intraspinal bronchogenic cyst localized to the sacral vertebra and associated with other malformations , which was surgically treated . a 5-month - old female was admitted to our neurosurgery department with a skin dimple in the sacral area . on admission to hospital , the patients general examination revealed no abnormalities except for a small skin dimple in the midline over her sacral vertebra . magnetic resonance imaging ( mri ) of the lumbar spine and sacrum was conducted at another hospital and revealed a 1.30.5 cm oval lesion at the s2 level . further , mri revealed a dermal sinus tract at the s2 level and a tethered spinal cord ( fig . a midline cutaneous incision was made and the sinus tract was dissected out from the subcutaneous tissues . the attachment of the tract to the dura was excised in an elliptic manner , and the dura was opened to visualize the subdural and the subarachnoid spaces immediately under the fibrous tract . the cystic mass was connected to the subarachnoid space through a slender pedicle from the dura ( fig . 2 ) . puncture of the mass yielded clear and colorless liquid , which was completely removed . after 9 days , she underwent an mri of the lumbar spine that revealed the complete excision of the dermal sinus and cyst and preservation of the neural tissues . the cyst was lined by one layer of ciliated columnar epithelial cells , and connective tissue was observed in the cystic wall . these pathological findings were concordant with those of endodermal cyst with respiratory epithelium ; therefore , we classified it as a bronchogenic cyst . endodermal cysts have been described using various names , including enteric cysts , enterogenous cysts ( 1 ) , neurenteric cysts ( 2 ) , gastrocytomas ( 3 ) , teratomatous cysts ( 4 ) , and archenteric cysts ( 5 ) . they are presumed to be derived from the endoderm of the developing gastrointestinal tract or , in rare cases , the respiratory system . endodermal cysts are typically intradural extramedullary lesions ( 6 ) , most commonly located at the level of the cervical spine ( 6 , 7 ) ; moreover , a ventral location is common ( 8) . other malformations of the spine are commonly associated with this disease entity . such as fused vertebrae , spina bifida , and hemivertebrae . the histological examination of the endodermal cyst wall typically shows a mucus - secreting columnar cell lining . in some instances , the bronchogenic variant can be differentiated by the presence of ciliated and nonciliated cells and goblets cells of the normal tracheobronchial tract . the cyst 's wall may contain mucus and serous glands , cartilage , smooth muscle , and ganglia ( 10 ) . in our patient , bronchogenic cysts are found most frequently along the tracheobronchial tree in the mediastinum or with the lung parenchyma . rarely , these cysts have occur in other locations , including cutaneous ( 11 ) and subcutaneous tissues ( 12 ) , the pericardium ( 13 ) , the diaphragm ( 14 ) , the abdomen ( 15 ) , and the spinal cord . to our knowledge , six intradural extramedullary bronchogenic cysts have been described in the literature , further , all of them were localized in the cervical , upper thoracic , or thoracolumbar segments ( 10 , 16 - 20 ) . the main hypothesis regarding the development of these malformations propose a faulty separation between the ectodermal and endodermal layers resulting in the inclusion of endodermal tissue within the ectodermally derived spinal cord ( 21 ) . incomplete excalation of the chordal plate would lead to the persistence of the neurenteric canal and the associated anomalies of the notochord would explain the commonly associated spinal and chordal anomalies ( 22 , 23 ) . due to the further differentiation of the endodermal layer into the digestive or respiratory tract , endodermal cysts may present with both types of histological features . in conclusion , although these cysts are generally located in the cervical , thoracic , or thoracolumbar spine , a sacral location should also be considered . moreover , in such cases , the early recognition of associated vertebral or spinal cord anomalies is essential .
intraspinal bronchogenic cysts are rare congenital cystic lesions . in all the reported cases , 
 the cysts have been located in the cervical , upper thoracic or thoracolumbar segments . 
 we report the case of an intraspinal bronchogenic cyst in the sacral location . 
 we present the case of a 5-month - old female with a skin dimple in the midline over the sacral vertebra . 
 magnetic resonance image of the lumbar and sacral vertebra revealed a dermal sinus tract and an epidural cystic mass at   the s2 level . 
 the patient underwent the removal of the dermal sinus tract and the cyst . 
 the cystic mass was shown to be connected to the subarachnoid space through a slender pedicle from the dura . 
 the cyst was diagnosed to be a bronchogenic cyst based on the results of the histopathological examination . 
 we conclude that intraspinal bronchogenic cysts may appear in the sacral location .