the present study included 1511 patients undergoing coronary artery bypass graft ( cabg ) during 2 years from 2007 to 2009 in sina hospital of esfahan . the sample size was defined based on previous studies.6 all patients gave their written informed consent before their surgery and entering into study . the study was approved by the research ethics committee of isfahan university of medical sciences , isfahan sina heart center . data for the studied patients including demographics , clinical characteristics , laboratory data , medical treatments , preoperative ( patients related factors and cardiac related factors ) , operative data and length of icu stay ( los ) were collected by reviewing hospital record files in a computerized database . perioperative mortality which was defined as death during 30 days from the operation was asked through telephone . totally , 149 patients were excluded from our study because of not replying to telephone . we used similar methodology previously applied by others with the same variables in the euroscore.121315 data were analyzed by logistic regression statistical test . accuracy ( validation and reliability ) of the euroscore was assessed by the area under the curve ( auc ) hosmer - lemeshow chi - square test was used to assess the calibration of the euroscore model . data analysis was performed by the spss soft ware ( version 14 , spss inc . , chicago , il ) . 24.9% ( 376 patients out of 1511 patients ) were female and 74.9% ( 1103 patients ) were male . logistic regression model calibrated well to our sample and gave p value of 0.89 in the hosmer - lemeshow chi - square test . odd ratios calculations revealed that predictive values for well - accepted risk factors such as unstable angina , sex and renal failure were not significant . left ventricular dysfunction , older age and neurologic dysfunction were significantly related to the mortality rate . clinical and demographic characteristics of the studied population association of euroscore risk factors of study population and occurrence of death by multivariate logistic regression analysis figure 1 shows percent distribution of risk factors among the patients . mean los , ranging from 0 - 49 days , was 2.5  2.5 days , and median was 2 days . the auc for the logistic euroscore was 0.66 ( 95% ci ) [ figure 2 ] . using the receiver operating characteristics ( roc ) curve analysis , we found an optimal cut off point with 66% sensitivity and 62% specificity that corresponded to the score of 0.028 ( in logistic euroscore ) being able to separate death probability from surviving probability . it means we can correctly predict 66% of the death ( sensitivity ) and 62% of the surviving ( specificity ) . percent distribution of risk factors in the study population receiver operating characteristics ( roc ) curve of euroscore for mortality prediction observed unadjusted preoperative mortality in our cabg patients was 3.6% almost equal to that of the other similar studies.41516 we concluded that euroscore would be relatively incapable of accurate prediction of perioperative mortality in our patients population and the most important target of our study was to confirm this assumption . european union concluded that additive euroscore model works well across european countries.17 geissler et al . compared 6 risk models and found the greatest auc for euroscore ( 78%).4 in nashef et al . study in north america , auc for euroscore was75%.16 other similar studies also reported near results.118 since the least auc for euroscore model in most of the studies was 75% and the auc > 70% usually demonstrates a good predictive value , it seems that euroscore risk model has less discriminatory power in predicting preoperative morality in our patients . in fact , according to the results , this risk model did not accurately predict preoperative mortality ; therefore , it may not be suitable for use in our patients population . in our study study result in which 17% of cabg patients stayed more than 2 days in the icu.19 although , pitkanen et al . reported 4.8% and 6.5% prolonged icu stay in their results , but mean los was 1.9%  1.9% and 1.4  1.9 days that was close to our results.20 although , it is obvious that reliable conclusion about the quality of care in individual hospital would require more information collection with validity assessment and we do nt argue about that in the present article , the quality of care provided in our hospital have been comparable with that of europeans countries . among risk factors , only 3 ones , age ( p < 0.02 ) , poor left ventricular dysfunction ( p < 0.03 ) and neurological dysfunction ( p < 0.03 ) , were found to be associated to mortality rate . other previously published studies claimed that all or most of these predictors had significant effects on morality rate . because of time limitation , the sample size of this study was smaller than similar studies . since these models were developed for specific patient population and they should not be applied elsewhere without appropriate validation for respective patient population , we recommend developing a risk model that can accurately predict perioperative mortality in our patient population waiting for cabg surgery with due attention to regional demographic and epidemiologic variables . mms designed the study and drafted this manuscript ; ma carried out the study and drafted the tables ; mg drafted the manuscript ; pn carried out the study and drafted the tables ; hsh helped in designing the study ; fms carried out the study ; ak helped in designing and carried out the study ; pms did the data analysis , and nf helped in data collection .
background : this study aimed to evaluate the accuracy of euroscore ( european system for cardiac operative risk evaluation ) in predicting perioperative mortality after cardiac surgery in iranian patient population.methods:data on 1362 patients undergoing coronary bypass graft surgery ( cabg ) from 2007 to 2009 were collected . 
 calibration was assessed by hosmer - lemeshow goodness - of - fit . 
 area under the curve ( auc ) was used to assess score validity . 
 odds ratios were measured to evaluate the predictive value of each risk factor on mortality rate.results:the overall perioperative in hospital mortality was 3.6% whereas the euroscore predicted a mortality of 3.96% . 
 euroscore model fitted well in the validation databases . 
 the mean auc was 66% . 
 mean length of intensive care unit ( icu ) stay was 2.5  2.5 days . among risk factors , only left ventricular dysfunction , age and neurologic dysfunction were found to be related to mortality rate.conclusions:euroscore did not have acceptable discriminatory ability in perioperative in hospital mortality in iranian patients . 
 it seems that development of a local mortality risk scores corresponding to our patients epidemiologic characteristics may improve prediction of outcome .