coronary artery disease is a major cause of morbidity and mortality in patients with diabetes who also have a high incidence of silent myocardial ischemia.3 atherosclerosis accounts for approximately 80% of all diabetic mortality , and about 75% of this is a consequence of coronary artery disease ; the remaining 25% results from accelerated cerebrovascular and peripheral vascular disease.4 patients with type 2 diabetes mellitus have a two to three - fold increased incidence of disease related to atheroma.5 the prevalence of diabetes mellitus among adults in saudi arabia is 11.8% and 12.8% among males and females respectively,6 and is expected to rise in the near future . in saudi arabia , diabetes has become a major cause of morbidity in the last two decades , apparently due to the sudden changes in lifestyle as a result of economic development , urbanization and competitive life.7 the reported percentage of risk factors for chd among saudi diabetic patients are as follows : high total cholesterol was 30%,810 high triglyceride ranged from 14%-30% which could be due to the variations in the cut off point used,810 overweight ranged from 33%-40,91112 and obesity from 30%-46%,91112 and hypertension was 22.1%.13 in al - rabwah primary health care center , where a mini - clinic for chronic diseases including diabetes mellitus has been run since 1998 , the present study was designed to estimate the percentage of risk factors for coronary heart disease ( chd ) among diabetic patients . because of the seriousness of coronary heart disease among diabetic patients and its association with modifiable risk factors , it is important to take steps to reduce these risk factors . the objective of this study was to assess the percentage of major modifiable risk factors for chd among diabetic patients attending the mini - clinic at al - rabwah phc center . the data was obtained from the mini clinics started in 1998 for chronic disease ( e.g. dm , hypertension ... ) . so far 495 diabetic patients have been registered ( 292 males and 203 females ) . on the first visit , to the clinic every registered patient had the history , physical examination and required investigations done in accordance with the manual of quality assurance in primary health care.14 two nurses , a male and female were trained and assigned to the clinic ; the male nurse to the male section and the female nurse to the female section . the same nurse used the same instruments to measure weight , height , body mass index ( bmi ) and blood pressure . all registered diabetic patients at this center , both men and women were included in this study . the following data were recorded : history of hypertension , bmi , smoking and laboratory tests including total cholesterol and triglycerides . in addition , age , duration of dm , and fasting blood sugar were also recorded . a hypertensive is defined either as a patient who is a known hypertensive on treatment , or as one who persistently has three or more successive readings of either systolic blood pressure 140 mmhg or above , or diastolic blood pressure 90 mmhg or above.15 total cholesterol and triglyceride investigations were done on instruction to fast for at least 12 hours . in this study , the average of the last three readings was taken for total cholesterol and triglycerides and patients were classified according to ncep ( atp iii).16 this means that patients were classified as follows : for total cholesterol ( 5.2- 6.2 mmol / l ) as a borderline and equal or above 6.2mmol / l as a high level . for triglyceride ( 1.7- 2.25mmoi / l ) as a borderline and equal or above 2.26mmol / l as a high level . obesity and overweight were defined using the average of the last three measurements of bmi and they were grouped according to the following who classification;17 bmi 25 -29.9kg / m for overweight , bmi 30kg / m for obese : class i obese : bmi 30 - 34.9kg / m , class ii obese : bmi 35 - 39.9kg / m , class iii obese : bmi > 40kg / m . using the american diabetic association 's goal of glycemic control cut - off point for fbs as 8.3mmol / l,18 the average of the last three readings of fbs was taken . descriptive statistics ( i.e. , mean and standard deviation ) were performed to describe the variables . descriptive statistics ( i.e. , mean and standard deviation ) were performed to describe the variables . a total of 495 diabetic patients files , 292 ( 59% ) males and 203 ( 41% ) females were studied . table 1 shows some baseline characteristics of the male and female patients , their similarities in mean age , mean duration of dm and mean fasting blood sugar . female diabetics had significantly higher mean total cholesterol ( 5.9mmol / l ) with high significant statistical difference ( p<0.0001 ) , a higher mean body mass index ( 32 kg / m ) with high significant statistical difference ( p<0.0001 ) and a higher mean hbalc ( 10.6% ) with high significant difference ( p<0.0001 ) . male diabetics , however , had a higher mean triglyceride ( 2.2 mmol / l ) with high significant statistical difference ( p=0.018 ) . baseline characteristics in 495 diabetic patients in al - rabwah phc in riyadh , 2001 ( means standard deviation ) the number and percentage of each risk factor for chd for the entire sample is shown in table 2 . four fifth ( 78% ) of the diabetics had high body mass index ( bmi>25 kg / m ) . high level of total cholesterol ( > approximately half of the patients ( 50.7% ) had high level of triglyceride ( 1.7mmol / l ) . of the diabetic patients , hypertensives represented 26% , 19.5% male diabetic patients smoked but none of the females did . the percentage of each risk factor for chd among diabetic patients in al - rabwah phc in riyadh , 2001 table 3 shows the number of patients and the result of statistical comparison between male and female patients for each risk factor sub - categories . there was a high percentage with significant statistical difference of high total cholesterol ( p=0.0001 ) , obesity ( p<0.0001 ) , borderline triglyceride ( p=0.026 ) , and hypertension ( p<0.0001 ) , among female diabetic patients . however , there was a high percentage of overweight patients with significant statistical difference ( p<0.0001 ) , and of smokers ( p<0.0001 ) , among male diabetic patients . percentage of risk factors of chd among diabetic patients by sex in al - rabwah phc in riyadh , 2001 the patients were divided into two groups based on the duration of diabetes ( table 4 ) . one group was for those who had had diabetes for more than ten years and the other for ten years or less . a comparison of the risk factors for chd among diabetic patients with regard to the duration of diabetes , more smokers ( p=0.011 ) were found in the group who had had it for less than 10 years . there was also a high percentage of morbid obesity ( p=0.011 ) , with significant statistical difference . other risk factors for chd did not seem to have a clear relation with the duration of diabetes . distribution of percentage of risk factors of chd among diabetic patients with regard to the duration of 10 years of dm in al - rabwah phc in riyadh , 2001 table 5 shows the division of patients into two groups based on the value of fbs , as a good control ( fbs > 8.3mmol / l ) or poor control ( fbs>8.3mmol / l ) . there was a high percentage with significant difference of borderline cholesterol ( p=0.02 ) , high cholesterol ( p=0.013 ) , high triglyceride ( p<0.003 ) , and obesity class i ( p<0.008 ) , among diabetic patients with poor glycemic control . however , there was also a high percentage of overweight with significant statistical difference ( p<0.026 ) in the group with good glycemic control . distribution of percentage of risk factors for chd among diabetic patients with respect to fasting blood sugar ( fbs ) as 8.3 mmol / l is cut - off point between controlled and uncontrolled group in al - rabwah phc in riyadh , 2001 the overall percentage of overweight was 35% , the rate being higher among men than women and the obesity rate was 43.3% and was higher among women than men . this was quite comparable to the results of other studies,911,12 in which overweight ranged from 33 - 40% and obesity from 30- 46% . the explanation of this may be that females had a more sedentary life with little exercise . in general , the bulk of high body mass index in diabetic patients could explain its role as a predisposing factor of dm type ii and as a risk factor for chd in diabetic patients . also high body mass index could lead to bad glycemic control and increased insulin resistance.20 the percentage of hypercholesterolemia in diabetic patients with the cut off point at 6.2 mmol / l was about 29% , affecting more females than males . moreover , with a lower cut - off point of 5.2 mmol / l , the percentage of hypercholesterolemia doubled . these results were quite comparable to the results of other researches done here in saudi arabia,89 and similar to that reported from diabetes surveillance ( 1999 ) in the united states , as abnormalities in lipids and lipoproteins were found in almost 30% of persons with diabetes.1 however , it was different from the framingham study , which revealed that female but not male diabetic subjects had a higher serum cholesterol level than their nondiabetic peers.19 the overall prevalence of hypertriglyceridemia among diabetic patients was about 30% . this result was similar to the result of the al - nuaim study,8 but higher than the result of the khalid and rumana study9 because of the level of cut - off point . this research and that of khalid and rumana9 showed that the rate of hypertriglyceridemia was higher among diabetic men than women , in contrast to al - nuaim study,8 where women had a higher rate of hypertriglyceridemia . also in the framingham study , triglyceride was higher in diabetic subjects but was only statistically significant in diabetic females compared to nondiabetic peers.19 however , when the cut - off point of the high triglyceride was reduced to 1.7mmol / l in accordance to ( ncep atp iii),16 the overall percentage of hypertriglyceridemia in diabetic patients reached 50% . therefore , hyperlipidemia is an important cause for atherosclerosis . atherosclerosis accounts for a considerable percentage of all diabetic mortality , the majority of which is the consequence of chd . the percentage of hypertension in diabetic patients was found to be 26% , the rate being higher among women ( or 5.17 ) than men . this result is much higher than that reported in the al - zubair study ( 21.9%),13 but less than that reported in the three - city study ( 47.2%).21 also both latter studies showed a higher rate of hypertension among diabetic patients , especially in females . the high percentage of hypertension in diabetic females can be explained by the high prevalence of obesity and the little physical activity among females . when hypertension coexists with overt diabetes , the risk for chd , stroke , and nephropathy is doubly increased . this is similar to the results of national chronic metabolic disease survey ( 21% ) of the general population.6 cigarette smoking is a leading risk factor of cardiovascular disease . the percentage of risk factors of chd among diabetic patients in respect to the duration of diabetes mellitus is worth discussing . smoking was less in patients who had had the disease for more than 10 years and the reason may be that with time , diabetics are more concerned about their health . however , there was no statistical difference with the duration of dm with regard to high body mass index , high total cholesterol , high triglyceride , and hypertension . this suggests that the risk factors of chd in diabetes may be present even during the asymptomatic hyperglycemic phase . this necessitates the need to ascertain the point at which the risk factors of chd come into play in the evolution from elevated blood glucose or insulin resistance . when fbs was used as a measure of the control of diabetes , there was a high prevalence of obesity and hyperlipidemia in the group with high fbs , possibly related to diet control and the major role it plays in the control of diabetes and its complications . this may explain the indirect role of stress in the rate of smoking and hyperglycemia . in general , this could explain the role of hyperglycemia in the risk factors of chd or even its association . achieving acceptable levels of glycemic control may be important for secondary as well as primary prevention of chd in diabetics . the clustering of risk factors of coronary heart disease is much higher among diabetic patients . the impact of these risk factors except for smoking which applies only to males is greater in females than males . this could explain the high rate of chd events and mortality in individuals with diabetes mellitus . because of these findings , an aggressive approach is needed and strategies have to be developed for the identification of the risk factors so that targeted preventive intervention measures could be undertaken through health education and healthy lifestyle . chd and diabetes awareness programs , periodic screening , and early therapy for those risk factors by general physicians are strongly recommended . finally , a more extensive study is needed to confirm these finding in relation to the duration and control of diabetes .
background : diabetes mellitus associated with high prevalence and incidence of chd is a common problem in saudi arabia.objectives:to assess the percentage of major modifiable risk factors for chd among diabetic patients.methods:this is a retrospective study conducted on 495 diabetic patients ( 292 males and 203 females ) attending the miniclinic at al - rabwah phc center in riyadh . 
 their records for the months of april and may 2001 were reviewed . 
 data collected from the patient 's files included body mass index ( bmi ) , blood pressure , total cholesterol , triglyceride , and smoking status . 
 in addition , information on the duration of diabetes was obtained and fasting blood sugar was done.results:the percentage of overweight males was 43.2% as against 22% females , the figure for males being highly significant ( p<0.0001 ) . 
 obesity which was 27.9% in males and 64.1% in females , was highly significant in females ( p<0.0001 ) . for cholesterol (  5.2 
 mmol / l ) was 49.5% in males versus 68.5% in females ( p=0.0036 ) . 
 high triglyceride (  1.7% ) was 50% in both genders . 
 13.4% of males were hypertensive as against 44.3% female hypertensives which was highly significant in females ( p<0.0001 ) . 
 19.5% of the males smoked . 
 there was no significant difference between risk factors for chd and duration of diabetes except that there were more smokers among those who had had diabetes for less than 10 years . 
 most of the diabetics with poor glycemic control ( fbs > 8.3mmol / l ) tended to be smokers , were more obese , had high triglyceride and high total cholesterol.conclusion:the findings indicated that diabetic patients have high percentage of risk factors for chd and more females than males are at risk . therefore , early intervention is required if the incidence of chd among diabetic patients is to be reduced .