india 's performance in relation to health and health - related parameters has in most respects been sub - optimal despite its rising economic , technological and diplomatic prowess . it has faltered in various key parameters such as under - five mortality rates , rates of malnutrition , and maternal deaths . the prevalence of noncommunicable diseases such as coronary heart disease , diabetes , cancer and mental illness is very high , and increasing in tandem with the rise of infectious diseases and antibiotic resistance . this is despite the fact that the government spending on health continues to hover around the abysmally low figure of around 1% of the gdp . this is among the lowest in the world and is even lower than the recommended spending of at least 2.5% of the gdp of the nation 's own planning commission . with a severely overburdened health system and a burgeoning population and the challenge of providing adequate budget for health , in an increasingly volatile global economy , health policy in india is ridden with increasing complexities and the need to make difficult choices . in a developing nation like india , where social determinants of health are all the more important as such using scientifically validated systems for policy - making , which limits bias and critically appraises available evidence and synthesizes it to best balance harms and benefits in health policy together with optimal scarce resources is a necessity which should now , with a plan to launch universal health coverage , no longer be overlooked . the article provides a brief overview on various challenges and opportunities related to incorporating evidence to inform health policy . key decisions on policy - making involve a significant amount of complexity and in a vibrant democracy like india involves a multitude of actors . as such the amount of priority any issue or agenda receives and how much resources is allocated is often dominated by what is on the  top of political agenda  rather than what is actually important . often involves significant trade - offs between varied competing interests ( often of powerful economic , social , and trade - union groups ) and often ignoring related more important issues to social values , ethics , and most importantly equity . as for example snakebites , which cause about 45,900 deaths annually in india and the epidemic of deliberate self - harm by consuming pesticides and rodenticides in india ( viewed in the background of farmer distress and gender inequity ) is not being acknowledged in spite of causing significant mortality , morbidity , and long - term disability . these conditions largely affect the poor , marginalized and deprived sections of the society who have very little political voice and thus their genuine healthcare demands continue to be neglected . with health , healthcare services and even health information being increasingly seen through the prism of fundamental human rights and in the purview of various international conventions , governments can no longer choose to remain arbitrary or listen to only powerful epistemic communities . using science ,   evidence  and  epidemiology  in the process of problem identification and agenda setting in the healthcare policy making will enable governments to effectively tackle allegations by  advocacy coalitions  and remain solution oriented instead of being problem oriented . faulty policies which do not take into account highest quality of evidence , even with the best of intentions , might cause problems for the government as well as government research institutions involved in research formulation policies . of particular note is the nation 's vaccine policy wherein a public interest litigation accused the agencies involved for serious misappropriations including promoting vaccines with little utility and questionable efficacy and safety in order to serve  vested interests . the litigation also accused the government on serious equity issues when it stated that the government was harping on costlier unnecessary vaccines , while it failed to provide the six basic vaccines to the poor and the marginalized section of the society . that the policy - making process in india is flawed has been demonstrated quite often . as for example , the drug control agency - unnerved on being reprimanded by the parliamentary standing committee on health and family welfare in its 66 report for failure to take appropriate action on various aspects of ensuring drug control and accused of playing with  health of crores ( tens of millions ) of our countrymen  suddenly issued a gazette notification which among other drugs also banned pioglitazone over concerns over its potential to cause bladder cancer . more than 3 million patients were on this relatively cheap anti - diabetes drug with a total market worth of inr 7 billion . as an immediate aftermath patient groups and medical professionals were confused , and there was immense lobbying on part of the pharmaceutical industry . soon media reports emerged that the decision for banning pioglitazone has being triggered on the basis of a letter from a noted diabetologist and not on any scientific evidence . with a brewing media storm , the government hastily set up a review board only to have its own ban revoked within 6 weeks of its declaration . at the end of the entire episode clinicians were more confused than before and patients were skeptical about using the drug . the government was also on the received end of severe criticism for not considering  hard evidence and ( being unable to ) balance the risks , benefits , and realities of indian clinical practice . systematic review and meta - analyses with a proper grading of the overall quality of evidence followed by a discussion on multiple stakeholders such that value judgments and trade - offs are sorted out at the onset itself are ideal best approaches to handle such encounters . this in effect means that the largely top - down approach of policy - making is replaced by a system , which synthesizes the top - down and bottom - up approach such that the extent of government capacity and desires as well as the peculiarities and complexities in the particular domain , which might facilitate or act as barriers to implementation of evidence is reconciled at the very start . empirical evidence  is sought in india only when a controversy sets in which lead to a confrontational state wherein there are accusation and counter accusations of partial and selective citation of scientific evidence as well as competing interests of those involved in the process of evaluating evidence . a scenario such as this leaves everyone in bad taste for a long time , while the  democratic debate  continues without any solution in sight . a system which routinely and prospectively appraises all available evidence based on predetermined criteria ( based on strengths , limitations and practicalities of the situation as costs ) and in a structured , systematic and transparent manner , which also monitors its implementation and impact can help win the trust of all stakeholders and make policies more acceptable . the utility and benefit of using reliable evidence in formulating policies particularly in resource - restrained settings has been demonstrated in india most notably after the tragic tsunami in 2004 . a few weeks after the disaster thousands in relief camps were suffering from posttraumatic stress disorder ( ptsd ) and how psychological interventions can be delivered for optimum benefits was a question that needed to be urgently addressed . mass - single session de - briefing by visiting villages was easy to deliver , the other option being more resource consuming process of identifying high - risk individuals and providing them supportive care and follow - up . evidence from a systematic review which showed that offering single - session mass debriefing did not only fail to reduce the odds of developing ptsd in the short term , but also increased the odds of ptsd in the long - term was then used to make an evidence - informed choice for health services delivery . in fact , the indian experience provided the trigger to cochrane collaboration to develop a separate arm called  evidence aid  which would provide valid , up - to - date and reliable evidence to aid policy - makers in the context of disaster settings . . a greater number of lay healthcare workers in program implementation has often been cited as a solution . multiple systematic reviews studying the role of lay healthcare workers in various settings provides the evidence , which might be used to further fine - tune the proposed usha ( under the new national urban health mission ) and the immensely successful asha so as to achieve maximal benefit without overburdening them . other decisions about designs , delivery and modes of various healthcare services can also be evidence - informed to ensure positive impact in terms of intervention outputs and outcomes related to health . formulating programs to address priority problems involves complex analysis of not only systems - related factors like financial constraints , time pressures , administrative , and technical capacity , but also extraneous factors like political constraints . as such providing an evidence - informed base so as to what works and what does not and their harms or role with relation to health equity and cost - effectiveness becomes inevitable for designing policies and programs and making them more accountable . it is also important to understand that an increasing demographic shift toward a more urban , educated and middle class values in india has meant that citizens question the impact of any policy , which involves public expenditure . with the right to information act and now the lokpal bill becoming a reality , it is imperative that governments monitor impacts of health policies in a systematic , transparent and rational manner in addition to the administrative functions of financial audits and adherence to rules and regulations . in a nation like india where significant health inequalities exist the impact evaluations should routinely include the impact of policies on bridging inequity . a well - developed policy evaluation system will help balance the policy to the needs and expectations of citizens as well as ensure the most efficient use of the resource and maintain quality of services . policy evaluation might also ensure that the policies do not deviate toward use of disproportionate and cost ineffective plans on account of powerful forces and influences of interest groups . as for example in spite of evidence and consensus that primary healthcare of populations are cheaper , of better quality and helps improve equity of care and increases access to health services there has been sustained high voltage media - campaigns by interest groups demanding increased number of super - specialty seats , more tertiary care , and even provisions for subsidy and incentives for providing specialist care . in absence of a proper policy evaluation and regulation system such powerful forces and influences might derail policy makers from investing properly in the overall development of health systems and instead get drawn into the vicious cycle if investment in the specialist tertiary care . with changing demographics and disease epidemiology india 's health policy needs a massive overhaul on an urgent basis but evidence - informed health policy is a reform that should precede any other . it is imperative at this point to state that 64 world health assembly in 2011 has urged member states  to establish and strengthen institutional capacity in order to generate country - level evidence and effective , evidence - based policy decision - making on the design of universal health coverage systems .  in a large and diverse nation like india such a mechanism will be needed at various levels - national , state and district . incorporating evidence in health policy has the dual advantage of acting both as a tool as well as a process , which not only pin - points when there is no or little evidence or when evidence is not being acted upon , but also drives funding agencies and government agencies to take steps to fill these gaps be it in knowledge creation , translation or implementation . an evidence - informed health policy system , which provide mechanisms to ensure equity , transparency , stakeholder involvement , feasibility and implement ability  all in a prospective , systematic and streamlined fashion with capability to make rapid adjustments based on feedback is a prerequisite to universal health coverage or for that matter any health reforms in the nation .
india plans to roll - out universal health coverage in spite of having one of the lowest governments spending on health in the world . a scenario such as 
 this means that health policy decisions particularly with respect to priority setting and resource allocation are often difficult and riddled with difficult choices . 
 moreover , a variety of decisions and determinants beyond the barriers of the health system has to be taken into account in a pluralistic and diverse nation like india during the healthy policy making process . 
 the review provides a brief overview on the current policy making scenario , where often decisions are not based on latest research evidence , but on placating powerful activist groups and is more problem oriented rather than being solution oriented . various opportunities which exist in order to incorporate evidence in order to inform health policy are discussed . 
 the article highlights the need to develop a transparent , inclusive and independent mechanism to prospectively appraise all available evidence and help inform policy - making based on predetermined criteria and to as evaluate the impact of policy decisions thereby helping in knowledge creation , translation as well as its implementation .