age - related macular degeneration ( amd ) is the leading cause of visual impairment among elderly white people in the developed world.1 the disease was initially thought to be uncommon in people with dark skin living in developing countries,2 but recent studies have shown that it is more prevalent in developing countries such as india3 and nigeria4 than previously thought . amd has also been shown to be an important cause of poor vision in the western57 and southeastern8,9 parts of nigeria . the reason for this is connected to the paucity of trained vitreoretinal surgeons and equipment necessary to make accurate diagnoses of this important cause of poor vision and blindness in the elderly population . in sub - saharan africa , the number of older people is currently increasing due to increased survival rates from improved health facilities ; hence , the increased number of persons being diagnosed with the disease . the recent explosion in published research about this disease suggest its increasing prevalence . in 2006 , we published on our experiences with retinal diseases in our institution and the need to establish a vitreoretinal center in the subregion.7 the international council of ophthalmology , international agency for the prevention of blindness , and a representative from carl zeiss , inc , visited our institution and helped initiate sponsored fellowship training in subspecialties including vitreoretinal . the patient load has increased , meaning that residents ( junior postgraduate doctors ) now have more cases to learn from . this review aims to determine if amd is a problem in our hospital , a teaching and tertiary public hospital located in ibadan , the largest city in sub - saharan africa . all retinal cases seen in the retina clinic between december 2007 and december 2010 were reviewed after subspecialization ( prior to 2007 , ophthalmologists at our hospital were nonspecialized ; now there are seven subspecialties : retina , cornea and anterior segment , glaucoma , orbit and plastic , pediatric ophthalmology , neuro - ophthalmology , and community ophthalmology ) . all case notes of patients with the diagnosis of amd were retrieved and included in the study . with the aid of slit lamp biomicroscopy using the 78d lens and fundus photography , the detection of soft drusen of < 65 m with pigmentary changes in the macula indicated early age - related maculopathy ( arm ) . the presence of drusen between 65 and 125 m ( size of vein at the disc margin ) , one large druse ( 125 m ) , or multiple large drusen without the advanced forms indicated intermediate arm . choroidal neovascular membrane ( cnvm ) is suggested by any of the following findings : macular scar , retinal pigment epithelium ( rpe ) detachment , subretinal blood , or exudates not accounted for by any other disease apart from arm . geographic atrophy is a well - demarcated area of macular rpe atrophy of at least 175 m in diameter . this suggests an advanced form of dry arm , also known as dry amd10 ( see table 1 ) . with the aid of slit lamp biomicroscopy using the 78d lens and fundus photography , the detection of soft drusen of < 65 m with pigmentary changes in the macula indicated early age - related maculopathy ( arm ) . the presence of drusen between 65 and 125 m ( size of vein at the disc margin ) , one large druse ( 125 m ) , or multiple large drusen without the advanced forms indicated intermediate arm . choroidal neovascular membrane ( cnvm ) is suggested by any of the following findings : macular scar , retinal pigment epithelium ( rpe ) detachment , subretinal blood , or exudates not accounted for by any other disease apart from arm . geographic atrophy is a well - demarcated area of macular rpe atrophy of at least 175 m in diameter . this suggests an advanced form of dry arm , also known as dry amd10 ( see table 1 ) . in the 3 years under review , 768 retinal cases were seen in the hospital , of which 101 ( 14% ) were diagnosed with amd . patients aged 6069 and 7079 years old constituted two - thirds of the cases ( table 2 , figure 1 ) . early arm had a steady rise while there was more intermediate arm in the 6069-years - old age group . the 7079 year age group showed a significant proportion of patients with early and late forms of both types of amd . more males presented with the advanced form of dry amd than females ( odds ratio = 2.33 ) . however , more females had advanced wet amd than males ( odds ratio = 1.85 ; see table 3 and figure 2 ) . amd is not uncommon and contributes to a significant proportion of ophthalmic presentation in ibadan , sub - saharan africa . this is contrary to previous reports that have suggested amd is uncommon in people of african descent.1117 the peak age of presentation in this study is similar to that in developed countries.1 the sex distribution is also similar to previous studies , with a slight female preponderance.1,12,13 more females presented with early amd and the late form of wet amd , while more males had advanced dry amd . cnvm from amd was found in about 40% of amd cases , as opposed to previous reports that have shown rates between 10% and 20%;7,14,15 this might be related to better examination and diagnostic procedures following subspecialization . dry amd was still responsible for more of the presentations when we consider the early form . intermediate amd with large drusen occurred in a significant proportion ( figure 3 ) ; hence , the need to educate patients about the benefit of the vitamin supplements suggested by the age - related eye disease study.16 this review has shown that most patients presented with the advanced stage of the disease ( figure 4 ) . with an increasing number of elderly people being diagnosed , provision of vision services is therefore imperative . six patients ( two males and four females , with an average age of 62 years ) presented with breakthrough vitreous hemorrhage necessitating vitrectomy . they had severe hemorrhagic pigment epithelial detachments similar to the cases described for idiopathic polypoidal choroidal vasculopathy.18 indocyanin green angiography is necessary to confirm the diagnosis of idiopathic polypoidal choroidal vasculopathy , but this was not available in our center . the presence of fundus fluorescein angiography and optical coherence tomography would increase the diagnostic yield for occult wet amd . the study was hospital based , possibly producing a higher prevalence of the disease ; hence , there is a need for a population - based survey . the need for patients education and regular eye examinations for the elderly is advocated in sub - saharan africa . a large population - based study is warranted to determine the true prevalence of the disease .
backgroundage - related macular degeneration ( amd ) is considered uncommon in black populations including those of sub - saharan africa . 
 the aim of this review was to determine the pattern of presentation of amd in our hospital located in ibadan , the largest city in sub - saharan africa.methodsa retrospective review of all cases with amd presenting to the eye and retinal clinic of the university college hospital , ibadan , west africa was undertaken between october 2007 and september 2010.resultsin the 3 years reviewed , 768 retinal cases were seen in the hospital , 101 ( 14% ) of which were diagnosed with amd . 
 the peak age was 6079 years . 
 the male to female ratio was approximately 2:3 . 
 more males presented with the advanced form of dry amd than females ( odds ratio = 2.33 ) . however , more females had advanced wet amd than males ( odds ratio = 1.85 ) . 
 wet amd was seen in 40 cases ( 40%).conclusionthe review determined that , as amd is not uncommon and wet amd is relatively more common in our hospital than has been reported previously , this is probably true of ibadan in general .