the synthesis of polymer therapeutics 
 capable of controlled loading 
 and synchronized release of multiple therapeutic agents remains a 
 formidable challenge in drug delivery and synthetic polymer chemistry . 
 herein , we report the synthesis of polymer nanoparticles ( nps ) that 
 carry precise molar ratios of doxorubicin , camptothecin , and cisplatin . 
 to our knowledge 
 , this work provides the first example of orthogonally 
 triggered release of three drugs from single nps . 
 the highly convergent 
 synthetic approach opens the door to new np - based combination therapies 
 for cancer .