to determine if retinal function is associated with myopia progression in children over a one - year period . twenty - two children ( mean = 111 years ) were recruited in this study . refraction and global flash multifocal electroretinogram measurements were performed at 49% and 96% contrasts at the initial visit and after 1 year . the amplitudes and implicit times of direct ( dc ) and induced components ( ic ) of the mferg responses were pooled into five concentric rings for analysis . pearson 's correlation ( r ) was performed to determine if myopia progression was correlated with the changes in these mferg 's parameters . the mean myopia progression was 0.450.34d ( range = plano1.38 ) . at 49% contrast , the ic implicit times from rings 2 to 5 ( r = 0.570.65 , p < 0.01 ) , and the dc implicit time at ring 3 ( r = 0.55 , p < 0.01 ) , were significantly delayed with myopia progression . at 96% contrast , only the ic implicit time within ring 1 was delayed ( r = 0.60 , p < 0.01 ) . in contrast , neither dc nor ic amplitudes at both contrasts were affected ( r = 0.110.28 , all p > 0.05 ) . myopia progression in children delayed ic implicit time at 49% contrast predominantly at the paracentral retina .
introduction : to determine if retinal function is associated with myopia progression in children over a one - year period.methods:twenty-two children ( mean = 111 years ) were recruited in this study . 
 refraction and global flash multifocal electroretinogram measurements were performed at 49% and 96% contrasts at the initial visit and after 1 year . 
 the amplitudes and implicit times of direct ( dc ) and induced components ( ic ) of the mferg responses were pooled into five concentric rings for analysis . 
 pearson 's correlation ( r ) was performed to determine if myopia progression was correlated with the changes in these mferg 's parameters.results:the mean myopia progression was 0.450.34d ( range = plano1.38 ) . at 49% contrast , the ic implicit times from rings 2 to 5 ( r = 0.570.65 , p < 0.01 ) , and the dc implicit time at ring 3 ( r = 0.55 , p < 0.01 ) , were significantly delayed with myopia progression . at 96% contrast , only the ic implicit time within ring 1 was delayed ( r = 0.60 , p < 0.01 ) . in contrast , neither dc nor ic amplitudes at both contrasts were affected ( r = 0.110.28 , all p > 0.05).conclusions : myopia progression in children delayed ic implicit time at 49% contrast predominantly at the paracentral retina . 
 these results support our previous findings ( ho et al . , 
 2011 ) that the effect of myopia development on retinal function is regional dependent .