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Patent US4562157 - Diagnostic device incorporating a biochemical ligand - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign inPatentsA device useful in diagnostics in which a biochemical species is attached to the surface of a sensor, especially to the gate of a field effect transistor. In such a "BIOCHEMFET" it has been a problem to attach two or more biochemical species to the surface of the sensor, especially to the gates of a...http://www.google.com/patents/US4562157?utm_source=gb-gplus-sharePatent US4562157 - Diagnostic device incorporating a biochemical ligandAdvanced Patent SearchPublication numberUS4562157 APublication typeGrantApplication numberUS 06/614,121Publication dateDec 31, 1985Filing dateMay 25, 1984Priority dateMay 25, 1983Fee statusPaidAlso published asCA1229883A, CA1229883A1, DE3468146D1, EP0127438A1, EP0127438B1Publication number06614121, 614121, US 4562157 A, US 4562157A, US-A-4562157, US4562157 A, US4562157AInventorsChristopher R. Lowe, Fergus G. P. EarleyOriginal AssigneeNational Research Development CorporationExport CitationBiBTeX, EndNote, RefManPatent Citations (5), Non-Patent Citations (3), Referenced by (333), Classifications (26), Legal Events (5) External Links: USPTO, USPTO Assignment, EspacenetDiagnostic device incorporating a biochemical ligand
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Herescope: The False Ragamuffin Gospel
Herescope was recently asked about the book Ragamuffin Gospel by Brennan Manning, which is a widely popular book. There are several excellent overviews on the Internet which put this book and its author in context, including here and here. The following report is reprinted below with permission from Lighthouse Trails Research:
Ragamuffin Gospel: A Distortion of Grace
Brennan Manning, a popular writer and speaker, is considered by many to be a kind of expert on the topic of God's grace. Philip Yancey, editor for Christianity Today magazine, says "Brennan Manning [is] my spiritual director in the school of grace." On the back cover of Manning's book, Ragamuffin Gospel, Max Lucado states: "Brennan does a masterful job of blowing the dust off of shop-worn theology and allowing God's grace to do what only God's grace can do - amaze." Few Christians would argue that we need God's grace, and in fact it is only through that grace that we can even approach God. Scripture is clear about this:
Ray Yungen, author and research analyst, says of Manning:
"His appeal is easy to understand when one hears Manning in person. His manner is very genuine and down-home. Many admire him for his passionate and dynamic character. When he relates how his mother mistreated him as a young child you cannot help but feel his pain deeply." (A Time of Departing, 2nd ed., p. 82)
Yungen adds, "However, despite all his admirable qualities and devotional intensity, he teaches contemplative prayer as a way to God" (p. 82). And here lies the problem. When we understand the premise of contemplative, we realize that it is impossible to promote both grace and contemplative at the same time. Grace and contemplative are on opposite sides of the pole. They completely contradict each other. John Caddock, in his excellent article, "What is Contemplative Spirituality and Why is it So Dangerous?" discusses this ragamuffin view of grace:
"Manning makes statements which imply universalism. In The Signature of Jesus, for example, he says that contemplative spirituality (which he calls paschal spirituality) 'looks upon human nature as fallen but redeemed, flawed but in essence good' (p. 125). For Manning the life, death, and resurrection of Christ mean that all are redeemed. There is nothing to be done to gain the life of God. Everyone already has it:
"He has a single, relentless stance toward us: he loves us. He is the only God man has ever heard of who loves sinners. False gods - the gods of human understanding - despise sinners, but the Father of Jesus loves all, no matter what they do. But of course this is almost too incredible for us to accept. Nevertheless, the central affirmation of the Reformation stands: through no merit of ours, but by his mercy, we have been restored to a right relationship with God through the life, death, and resurrection of his beloved Son. This is the Good News, the gospel of Grace" (The Ragamuffin Gospel, p. 18).
"Manning says that God loves 'all.' He is not speaking here merely of the compassion God has for the world which moved Him to send His Son to die for us (John 3:16). He is saying that God has already restored all people to a right relationship with Him. Notice that he first says 'he loves us' and then 'he loves all.' Clearly us, the first person plural pronoun, in this context includes everyone. Then, in the same context Manning goes on to say that "we have been restored to a right relationship with God." We, there is the same group as the all mentioned earlier. All have been restored to a right relationship with God. Manning wants us to overcome our psychological fog so that we can realize it. The Good News is that everyone is already saved. The biblical view that all are lost and that only when a person trusts Jesus Christ as Savior he passes from death to life (John 5:24) is foreign to Manning and contemplatives."
So while on the surface, Manning appears to be teaching God's grace, it is a "grace" that has been distorted and twisted. And woven dangerously throughout Manning's writings is a spirituality (contemplative) that will lead his followers more into the arms of mysticism and altered states of consciousness than into the arms of Jesus Christ. Caddock goes on:
"[T]he key to spirituality, according to Manning, is a special type of prayer which he calls 'contemplative prayer' or 'centering prayer.' For the uninitiated, this may not seem ominous. It may sound like what God calls us to do in His Word. It is not. It is ominous. It is a practice derived from Eastern mysticism. In The Signature of Jesus, Manning writes, 'The task of contemplative prayer is to help me achieve the conscious awareness of the unconditionally loving God dwelling within me' (p. 211). He also says, 'What masters of the interior life recommend is the discipline of 'centering down' throughout the day' (p. 94)…. He instructs the reader in the practice of centering prayer:
"[T]he first step in faith is to stop thinking about God at the time of prayer"(p. 212)! ….
"The second step, according to Manning, is to 'without moving your lips, repeat the sacred word [or phrase] inwardly, slowly, and often' (p. 218)….
"The third step concerns what to do when inevitable distractions come. The answer is to 'simply return to listening to your sacred word. Gently return your mind to your sacred word' (p. 218).
Finally, 'after a twenty-minute period of prayer [which Manning recommends twice daily] conclude with the Lord's Prayer, a favorite psalm, or some spontaneous words of praise and thanks'" (p. 219).
While such instruction leaves little to doubt as to Manning's affinity towards contemplative, his consistent promotion and obvious admiration for numerous mystics is even more remarkable. In Ragamuffin Gospel, Manning favorably quotes Basil Pennington, Sue Monk Kidd, Anthony de Mello, Henri Nouwen, Francis de Sales, Gerald May as well as Marcus Borg, and Alan Jones. Every one of these names is connected with New Age mysticism and a unbiblical view of the Gospel. Alan Jones, in his book, Reimagining Christianity says:
"The Church's fixation on the death of Jesus as the universal saving act must end, and the place of the cross must be reimagined in Christian faith. Why? Because of the cult of suffering and the vindictive God behind it" (p. 132).
In spite of Jones' disdain for the biblical message of Jesus Christ dying on the Cross to save sinners, Manning favorably quotes him, not just in Ragamuffin Gospel but four times in his book The Signature of Jesus. Actually, Manning quotes a who's who of Eastern-style meditation teachers in that book. Some of them are: Thomas Merton, Anthony de Mello, Basil Pennington, David Steindl-Rast, William Shannon (Silence on Fire) and Henri Nouwen. These are some of the most serious contemplatives. And by that, I mean they believe (or did believe when they were alive) that God is in every human being, thus all are saved. If this were true, then God the Father made a terrible mistake in sending his Son to die, for it would have been an unnecessary act.
Unfortunately, the type of grace that Manning and these other authors promote is so intermingled with New Age thought that it is not the grace that Hebrews 4 speaks of but is rather a belief system that leads followers down a pantheistic, mystical path and further and further away from the Cross. In Manning's more recent book, Above All, he says:
"[T]he god who exacts the last drop of blood from his Son so that his just anger, evoked by sin, may be appeased, is not the God revealed by and in Jesus Christ. And if he is not the God of Jesus, he does not exist" (p. 58).
Manning actually took this idea, nearly word for word, from William Shannon, author of Silence of Fire (p. 110). But Manning has made a habit of quoting Shannon. Ray Yungen elaborates:
"[W]hen Manning quotes from (and even recommends in one interview) William Shannon's book, Silence on Fire, one would expect to find a common ground somewhere between the two of them. Yet Silence on Fire contains nothing that would inspire a true evangelical. In fact, it is filled with universalist statements that would offend anyone with doctrinally-sound evangelical sensibilities. One portion states,
"[T]here is a oneness in God that unites all women and men ... The goal of all true spirituality is to achieve an awareness of our oneness with God and with all of God's creation." (A Time of Departing, p. 87)
Alan Jones, whom Manning also repeatedly quotes, calls the doctrine of the Cross a vile doctrine. This rejection of the biblical view of the Cross by Jones and Shannon is similar to that of Brian McLaren [of Emergent Church fame, ed.] who says the doctrine of the Cross and Hell are "false advertising for God." Such a view insists that a loving God would not send his Son to a violent death on a Cross, and yet we know that He did do that to His Son, who took the place for others who because of their sin, deserved such wrath. Now that is what I call true grace.
posted by Discernment Research Group @ 11/02/2006 03:43:00 PM

type: global

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#68 of 449 Restaurants in New Haven $$ - $$$
88 helpful votes “Great pizza, beer, music and people ”
31 helpful votes “good pies, but not the best pies.”
Takeout, Serves Alcohol, Reservations, Seating, Waitstaff, Television, Full Bar
Posting guidelines Get notified about new answers to your questions. Ask Typical questions asked: Do you have gluten-free options? Is there a dress code? Do you allow dogs on the outdoor patio? Near Bru Rm At BAR Top-rated Attractions Nearby 683 Reviews Yale University Art Gallery
104 Reviews Olea

value: Tripadvisor, Inc. is an American online travel company that operates a website and mobile app with user-generated content and a comparison shopping website.


text:
Colorful Cross with Blue Flower Print of an original
Colorful Cross with Blue Flower - Print of an original watercolor painting on a cedar wood block (3 3/4"L x 5"H x 1 1/2" W)
To create this mixed-media artwork, I decoupaged a high resolution Indigo Digital Press print of my original watercolor painting to a cedar wood block. The block itself measures 3 3/4"L x 5"H x 1 1/2" W and is wide enough to stand prettily by itself on a shelf. The back of the cedar block is left natural and is signed by Carla Starling Quigley.
The cross in this painting is a refreshingly simple and colorful design which is pleasing to the eye. It has a blue flower in the center and straight leafy branches covering the arms of the cross. The side of the wood block has a delightfully textured border in red and blue dots.
Materials: cedar wood, digital press print, original watercolor art, textured paint, acrylic sealer, acrylic paint
Make a Joyful Noise to the Lord - Print of an original watercolor painting on a cedar wood block (4"L x 5 1/4"H x 1 1/2" W) - home decor
Print of an original watercolor painting - A Song of Ascents - on a cedar wood block (5 1/4"L x4 1/2 "H x 1 1/2" W) - art block - home decor
Print of an original watercolor painting - HARVEST MOON - on a cedar wood block (5 1/4"L x4 1/2 "H x 1 1/2" W) - art block - home decor
Christ Pantocrator - Print of an original watercolor painting on a cedar wood block (5 1/4"L x 5 1/4"H x 1 1/2" W) - mounted art print
ICHTHYS (Big Fish) - Print of an original watercolor painting on a cedar wood block (4"L x 5 1/4"H x 1 1/2" W) - art block - home decor
Blue Blooming Tree - Print of an original watercolor painting on a cedar wood block (4"L x 5 1/4"H x 1 1/2" W) - art block - home decor
Purple Doodle Tree - Print of an original watercolor painting on a cedar wood block (4"L x 5 1/4"H x 1 1/2" W) - art block - home decor
Green Willow Tree - Print of an original watercolor painting on a cedar wood block (4"L x 5 1/4"H x 1 1/2" W) - art block - home decor
6-3/4"L x 10-1/2"H Wood photo frame with print
Expandable Bamboo Poles Trellis, 72"'L x 48"H, BFF-48P
Expandable Bamboo Poles Trellis, 72"'L x 36"H, BFF-36P
Bamboo Bar Counter with Shelves, 24"W x 64"L x 44"H, BB-24
Seated Bamboo Arbor, BNA-60S, 84"H x 54"
cedar wood block

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text:
Handy Crafts: Transitions
Today is the day I have been anticipating, dreading, looking forward to since I got pregnant. 25 weeks, 2 days. Last year, on July 4, I was 25 weeks, 2 days pregnant with Eliza. And I lost her. It was the worst day of my life. But this year, on April 27, I am 25 weeks, 2 days pregnant with Vivian. And she's doing great. She's big and strong and active. I'm on medication, and my blood pressure is behaving. There is no sign of the horrible swelling that I had last year. I have energy, and am sleeping pretty well. At this point, there isn't much more I could ask for.
We had our ultrasound on Wednesday, which was a huge relief for me. The doctor was very thorough, and looked hard at the blood flow through the umbilical cord, which looked good. He thinks that Vivian is actually big for her gestational age, already 1 lb., 15 oz. For comparisons sake, Eliza was only 1 lb., 2 oz. when she was born. So Viv is growing big and strong. All of her measurements are in the 80-95th percentile (except for her legs, only 54th percentile. Well, looking at her family, I guess it makes sense that she'd be big all over, but with short, stumpy legs).
And tomorrow starts a new phase, one that I'm really looking forward to. Our next milestone is 28 weeks, when, if something happened, and Viv needed to be born early, she'd have a pretty good chance, not only of surviving, but of surviving without major health issues. We'll have another ultrasound then, and another chance to see how Viv is doing.
We're in a good place, and I'm excited to move forward.
Baby Vivian is flexible!
Labels: baby, pregnancy, Pumpkin
Hooray for big babies - grow Viv, grow! :)
She's folded in half! It is amazing, how babies contort themselves.
You guys are doing so well - here's to 28 weeks, and to it being just another milestone on the way to full term.
Congrats! She's gorgeous! And definitely a future Olympic Gymnastic champion!
Woo hoo for your big baby! I'm so glad to hear she's doing well and is such an active little girl.
that is MORE THAN flexible. that is gumby!
Go Peigi Go said...
Rollo and I are thinking of you often and glad to read that you are doing so well!
Yay! She will be an olympic gymnast. Maybe the kind that runs around on the mat with ribbons on sticks. I always liked that event.


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Orlando Metropolitan Resort (Florida) - Hotel Reviews - TripAdvisor
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There are newer reviews for Orlando Metropolitan Resort See the most recent reviews Showing 985:
72 helpful votes “Mostly Unsavory...need a shower after staying here”
Trying to find some good positive comments on the Metropolitan isn't easy...well it's a good location along I-Drive and they have a nice large pool, plenty of parking, nice grounds, pool rest room (wash-room) is good & got plenty of use. More on that later.
On arrival discovered this place is a motel (outside doors to rooms) not a hotel...
Thank Gary A Report LynSt, Manager at Orlando Metropolitan Resort, responded to this review
Thank you for taking time to write a review about our hotel. We apologize that you did not enjoy your stay with us. We value your business and we are in the process of upgrading our hotel. We hope you will give us another try in the future.
More Robert999may2nd
Went here on vacation with my family needed a hotel near attractions that was clean comfortable and easy to get too. The staff here was very friendly and helpful to my family as I had to work while here. Recommend this hotel for a clean comfortable place to stay on a budget.
Thank Robert999may2nd Report LynSt, Manager at Orlando Metropolitan Resort, responded to this review
Thank you for taking time to write a review about our hotel. We value our guest and we are delighted in having you recommend us. Please let us know if there is anything we can do for you in the future. Have a wonderful day!
More Millsy-Ger
1 review 3 helpful votes “I will not be back”
We stayed there for 14 nights and most of those nights we ended up at the front desk . Our first room we got was next to a lift which made a racket through the night , the rooms shower didn't work too , so we were moved. This room seemed ok but a few nights later we came back...
Thank Millsy-Ger Report LynSt, Manager at Orlando Metropolitan Resort, responded to this review
Thank you for taking time to write a review about our property. We apologize that your stay was unsatifactory. We are currently upgrading our hotel which include new door locks, fixing the elevators and rooms. We use our reviews for learning tools.
Show Prices carolMaidstoneKent
18 helpful votes “very good value for the money”
After booking our holiday and then reading all the reports on the Metropoliton Resort International Drive i must admit i was more then scared after commiting all that money but i need not have bothered it was great, but thats not to say we didn't have a few hick-ups!!!!!!! I had emailed the hotel prior to our arrival because our...
Thank carolMaidstoneKent Report LynSt, Manager at Orlando Metropolitan Resort, responded to this review
Thank you for taking hte time to write a review about our hotel. We are delighted that you had a wonderful stay and with the few issues you had we are using them as learning tools. Again Thank you for your business!!
More carlosban
We arrived on the 6th of april after being up 24 hrs to walk to reception and to be ignored for nearly 20 mins and when we were seen, they tried to give us two rooms instead of already paid for three. The rooms are dark, and smell of smoke and dampness, the hotel could do with a complete makerover,...
More Helpful? Thank carlosban Report Chrissi007
1 review “Best Value for Money in Orlando”
A nice hotel to visit, we got very good value for our money, the continental breakfast is taken in the Raddison, sister hotel,next door, and is very good.The YMCA , also joined to the hotel,is also a good bonus if you are interested in any kind of activities as the hotel gives you passes for free use of their facilities,...
More Helpful? Thank Chrissi007 Report sunshine32511
Level Contributor 3 reviews 4 helpful votes “Will NEVER stay here again!”
Upon getting up in the morning, my co-worker found a pair of dirty socks that were left by a previous person in the sheets. The sheets could not have been changed before we got there and after the previous person left. That is gross! Very unsettling. I asked for a refund and told me to go to Expedia to get...
Thank sunshine32511 Report gdolynne
1 review “Pass on this hotel is strongly suggested!”
I would not stay here again and I really didn't want to stay when I was there.Hotel rooms were not clean, staff at the front desk were not friendly at all or helpful. Room was not cleaned everyday and sheets not changed. The only good thing was the lady that sells the tickets in the lobby, she was very nice...
More Helpful? Thank gdolynne Report awesome34438
1 review “I will stay is this Hotel Anytime”
The Customer Service in this Hotel was awesome. Regina the Sales Manager was amazing in helping me reserve the rooms. Very Clean Hotel and The pool was very nice and Clean. The youth from our church had a great time at the pool and no one complain about the room or the hotel. I will stay in this hotel again....
More Helpful? Thank awesome34438 Report HeatherNaramoreAdams
1 review “Aweful,not worth the money,worst ever”
My family was stuck in malfunctioning elevater upon arriving at 4 in the morning for 30 minutes.Their were no working ice machines on any floor.There website says they have a pool and hottub this actually at the ymca for an extra 5 bucks.Their website also says refridgerators in room but when we ask why they wernt cold were told they...
More Helpful? Thank HeatherNaramoreAdams Report Previous
#289 of 336 in Orlando 1,428 reviews
#283 of 336 in Orlando 739 reviews
TripAdvisor is proud to partner with Expedia, Booking.com, Odigeo, Priceline, Travelocity, Cancelon and Hotels.com so you can book your Orlando Metropolitan Resort reservations with confidence. We help millions of travellers each month to find the perfect hotel for both holiday and business trips, always with the best discounts and special offers.


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Alpenhotel Panorama (Resia, Italie) - voir les tarifs et avis hôtel - TripAdvisor
Hôtels proches de la Alpenhotel Panorama
Restaurants près de Alpenhotel Panorama
À faire près de Alpenhotel Panorama
Alpenhotel Panorama, Resia
Nº12 sur 19 B&B/auberges à Resia
Neudorfstraße 16, 39027 Resia, Curon Venosta, Italie
78,9 km de Aéroport d'Innsbruck-Kranebitten
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Obtenez des réponses rapides du personnel et des anciens clients de Alpenhotel Panorama.


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Jack Aydin, Keybanc Capital Markets Inc: Profile & Biography - Bloomberg
Former Sr Mng Dir/Analyst:Energy,
Sr Mng Dir/Analyst:Energy
Keybanc Capital Markets Inc, 4/2007-7/2014
Sr Managing Director/Analyst
Keybanc Capital Markets, 4/1973-4/2007
Board Member, 7/2014-3/2017
New York Security Analyst
The Oil Analysts Group of New York

value: Bloomberg News (originally Bloomberg Business News) is an international news agency headquartered in New York City and a division of Bloomberg L.P. Content produced by Bloomberg News is disseminated through Bloomberg Terminals, Bloomberg Television, Bloomberg Radio, Bloomberg Businessweek, Bloomberg Markets, Bloomberg.com, and Bloomberg's mobile platforms. Since 2015, John Micklethwait has served as editor-in-chief.


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normalization - When I normalize the standardized values of data, why do I get the same values as just normalizing? - Cross Validated
In the second column, I standardize VAR1, subtracting the mean and dividing by the standard deviation. In the third column, I normalize VAR1 with the formula:
$$\frac{x - \min(x)}{\max(x)-\min(x)}$$
In the fourth column I normalize the standardized values of VAR1 (using the above mentioned formula, on column 2).
Can you tell me why columns 3 and 4 are the same?
data-transformation normalization standardization
The easy answer is that standardization and normalization are linear transformations of the data and any line is determined by two distinct points on it. Since columns 3 and 4 are constructed to include the points $(\min(\text{data}), 0)$ and $(\max(\text{data}), 1)$ (namely, $(2,0)$ and $(95, 1)$), they must result from identical transformations.
The algebraically rigorous answer manipulates the formulas. Recall that standardization of data $\mathbf{x} = x_1, x_2, \ldots, x_n$ replaces each $x_i$ with
$$y_i = \frac{x_i - \bar x}{s_x}$$
where $\bar x$ usually is the (arithmetic) mean of the data and $s_x$ often is a standard deviation of the data. (Generally, $\bar x$ may be any estimate of a central value and $s_x$ may be any estimate of the spread, but such generality is usually not intended.)
On the other hand, normalization replaces each $x_i$ with
$$z_i = \frac{x_i - \min(\mathbf{x})}{\max(\mathbf x) - \min(\mathbf x)}.$$
But since $s_x \gt 0$, division by $s_x$ is an increasing function. Subtracting any constant like $\bar x$ similarly is an increasing function. Therefore the extremes of $\mathbf x$ correspond to the extremes of $\mathbf y$. Consequently, normalization of $\mathbf y = y_1, y_2, \ldots,y_n$ produces
$$\eqalign{ z_i^\prime &= \frac{y_i - \min(\mathbf{y})}{\max(\mathbf y) - \min(\mathbf y)} \\ &= \frac{\frac{x_i - \bar x}{s_x} - \min_j(\frac{x_j - \bar x}{s_x})}{\max_j(\frac{x_j - \bar x}{s_x}) - \min_j(\frac{x_j - \bar x}{s_x})} \\ &= \frac{{x_i - \bar x} - \min_j({x_j - \bar x})}{\max_j({x_j - \bar x}) - \min_j({x_j - \bar x})} \\ &= \frac{x_i - \min(\mathbf{x})}{\max(\mathbf x) - \min(\mathbf x)} \\ &= z_i. }$$
Not the answer you're looking for? Browse other questions tagged data-transformation normalization standardization or ask your own question.

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Amazon.com: Running for Women: Your Complete Guide for a Lifetime of Running eBook: Jason Karp, Carolyn Smith: Kindle Store
Buy a KindleKindle eBooksAdvanced SearchDaily DealsFree Reading AppsKindle SinglesNewsstandAccessoriesDiscussionsManage Your KindleKindle Support Start reading Running for Women on your Kindle in under a minute. Don't have a Kindle? Get your Kindle here.
Running for Women: Your Complete Guide for a Lifetime of Running [Kindle Edition]
Jason Karp (Author), Carolyn Smith (Author)
Running for Women provides comprehensive information on training female runners based on their cardiovascular, hormonal, metabolic, muscular, and anatomical characteristics. Women will learn to maximize workouts around the menstrual cycle and to guard against common injuries, disordered eating, osteoporosis, and menstrual irregularities. Show more
Running for Women provides comprehensive information on training female runners based on their cardiovascular, hormonal, metabolic, muscular, and anatomical characteristics. Women will learn to maximize workouts around the menstrual cycle and to guard against common injuries, disordered eating, osteoporosis, and menstrual irregularities. Customers Who Bought This Item Also Bought
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Jason Karp, PhD, is an exercise physiologist, a running and fitness expert, and the 2011 IDEA Personal Trainer of the Year. He offers science-based coaching to runners of all levels and consulting to coaches through his company, RunCoachJason. He is in demand as a presenter at numerous coaching, fitness, and academic conferences, including U.S. Track & Field and Cross Country Coaches Association, American College of Sports Medicine, American Society of Exercise Physiologists, and IDEA World Fitness Convention. Karp is also a prolific writer, with four books and more than 200 articles published in magazines, including Runner’s World, Running Times, Shape, Oxygen, Self, and Ultra-Fit. Karp has enjoyed success coaching at high school, college, and club levels. He has taught USA Track & Field’s highest level of coaching certification and was an instructor at the USATF/U.S. Olympic Committee’s Emerging Elite Coaches Camp at the U.S. Olympic Training Center. The founder and coach of REVO2LT running team and a competitive runner himself, Dr. Karp is a USA Track & Field-certified coach and is sponsored by PowerBar as a member of PowerBar Team Elite. Karp received his PhD in exercise physiology with a physiology minor from Indiana University in 2007, his master’s degree in kinesiology from the University of Calgary in 1997, and his bachelor’s degree in exercise and sport science with an English minor from Pennsylvania State University in 1995. Dr. Karp has taught exercise physiology and biomechanics at several universities and taught in the fitness certificate program at the University of California at Berkeley. He is currently an adjunct faculty member at Miramar College in San Diego, where he teaches applied exercise physiology. Carolyn Smith, MD, is a family practice and sports medicine physician who serves as director of the student health service at Marquette University and head medical team physician for the department of intercollegiate athletics. She also maintains her teaching interests in her role as medical director for the athletic training education program. Smith is a versatile runner with a career that has spanned more than three decades. After a postcollegiate career running shorter distances, Smith embraced ultrarunning in 2002 and has enjoyed success in distances ranging from the 50-mile run to the 24-hour run. She is a former 24-hour and 100K national champion. She has had the privilege of representing the United States on two 24-hour national teams (2005, 2007) and is a 100K national team member (2004, 2007, 2008, 2009, 2010, 2011, 2012). She is a national age-group record holder. In 2009, she held the fastest time in the world for the 50-mile ultramarathon and was ranked No. 1 in that event in the United States. In 2011 she set a national age-group record for the 12-hour run, finishing first among all participants in the FANS 12-hour ultramarathon in Minnesota, running 83 miles in 12 hours - more than 12 miles ahead of the second place finisher. She represented the United States for the seventh time in the 100-Kilometer World Championship, which was held in Italy in 2012. In 2012 the U.S. women’s team won the gold medal, an accomplishment Smith was also a part of in 2009. In addition to a medical degree from the University of Illinois, Smith holds a master’s degree from Northern Illinois University and a bachelor’s degree from the University of Wisconsin, both in exercise physiology. Following a faculty position with the St. Michael Hospital Residency Program in Milwaukee, and the Medical College of Wisconsin, Smith joined the Marquette University student health service in 2002. Product Details
ASIN: B008BMP6R6
Amazon Best Sellers Rank: #444,885 Paid in Kindle Store (See Top 100 Paid in Kindle Store)
Dr. Karp's book has answered all of our questions and then some. ”
Throughout the book there are clear charts about training programmes, broken down into various categories. ”
Keith M. H. Donald|
This author is well knowledged and represents this information in a way that was easy for me to understand! ”
Christinel|
Serious Science for Serious Runners
Format:Paperback|Amazon Verified Purchase This books is great- it explains the science behind improving running, instead of just giving instructions or giving anecdotes. The female-specific information covers issues that I have never seen before: monthly hormonal changes, female anatomy, and specific health issues for women. It also provides practical advice, with weekly plans and stretches and strength training. All movements (stretches and strength training) have clear directions and images. This book is probably not for the "couch-to-5k" beginner, but for the runner who is ready to improve on her running. If you're ready to really understand running and see some improvement, this book will not disappoint!
Running women should get this book!
Format:Paperback I got this book for my fiance'. I consider myself a serious intermediate runner, and my fiance' a solid intermediate runner (she has been running for several years up to the half marathon distance). I can't tell you how valuable the information in this book has been for both of us. I recall several runs where my fiance' would notice she just didn't have the energy she normally did, or her perforance would suffer for reasons she couldn't understand. Dr. Karp's book has answered all of our questions and then some. It provides highly valuable and insightful information about female physiology and the reasons performance and health are impacted by different physiological responses. It provides extremely useful guidance on the best way and times to train, how to adjust for menstruation, pregnany, and aging and even highlights the best times to achieve peak performance given a woman's menstrual cycle (this is when we try to schedule our races :-)). It has really adjusted our thinking and approach to running, and how my fiance' and I now train together (which has had the added benefit of minimizing...er...um...what I will call "training disagreements"). It really has made a world of difference in her performance and overall health and well being. Thanks to Dr. Karp for such great, practical easy to digest information. This truly is a must read for both women runners and the men that support them.
Helpful resource for runner gals
Format:Paperback Got this book a few weeks ago and loved it; I'm actually thinking of buying it as a Christmas present for one of my friends. I've bought several books on running along the years, but what I liked most about this one is that it presents serious, scientific and practical information in a concise and clear manner, while managing to remain an easy read and not at all overwhelming or confusing; content flows easily and information is easy to understand and most importantly, apply. Also, I think both beginner and more experienced runners would find this book resourceful.
So very helpful for everyone who runs ..........
Format:Paperback I am not the obvious person to read, (and to review), this book: male runner, veteran (master) 55-59 age group. However, I race against women, I train with them, my wife is an occasional runner and my daughter runs to keep fit. In short, you do not have to be of the female gender to appreciate this book's depth and value to the sport. This book is written with women in mind but should be read by all of us with an interest in the sport and a wish to support our fellow female competitors and training companions.The combination of Karp and Smith is perfect. Karp is a physiologist and in 2011 was the Personal Trainer of the Year, voted by I.D.E.A. He coaches at the highest level. Smith is a renowned ultra-runner, having stepped up from shorter distances, and is a family diction and sports' medicine physician.Their experience comes together in this readable, comprehensive book. Written with all age groups and levels of performance in mind, "Running for Women" explains the physiology of women and gives clear guidance as to the types of training and racing which should be undertaken at each stage in the cycle. The guidance is broken down in terms of age of the athlete, the number of "miles in the bank" and the impact on the runner of the athlete's menstrual cycle.Throughout the book there are clear charts about training programmes, broken down into various categories. There are paragraphs on balancing motherhood and training, running with a group and the several components of training. The photographs add value too and feature in most chapters.Of particular importance are the detailed sections on running when pregnant, and the importance of a balanced diet to maintain health and peak performance. Quite frankly, it is vital that that older female runners note Karp's and Smith's recommendations on the prevention of bone loss; adequate estrogen is vital to bone health. If you are female runner, read the book to find out more and to have the best chance of remaining fit and healthy whilst continuing to enjoy the sport.I learnt a lot when reading this book. Whether you are female or male, this is a really important addition to our library giving us clear guidance on how the female runners can remain fit and healthy at every stage of their running career. Read more ›
By M. Nir
Format:Paperback NB: I received a copy of this book through the LibraryThing Early Reviewers program.Running for Women, like other books produced by Human Kinetics, is a book with serious exercise science. It gives a complete overview of how running affects your body, as a woman, and how women's bodies can enhance or complicate the activity - through structural differences in our pelvises and legs and hormonal ones at various stages in our lives and hormonal cycles. I found the book really informative, and, though heavy on the science, easy to understand. It might be most helpful for serious runners - I only run 1-2 times a week, and still have 5 miles as a goal I haven't hit (I run 3-4 miles a session), and so some of the information I wasn't quite sure that I could make use of, because I run so lightly. But even for the casual runner/jogger, I think the information is interesting and useful - understanding how running impacts my body has already changed the way I run in small and useful ways.I would also recommend the imprint for anyone who has questions about how exercise impacts bodies - I have become really fond of Human Kinetics through the two books I have read: they are thorough, clear, and very informative!
Intellectually comprehensible by merging many subject areas about... "Running for Woman," I am astounded at the quality behind everything I have read. This is a book that will help you understand the physiological aspects behind running. Read more
Published 3 days ago by Bookworm80
Rubbish! How do you write a 218-page book about running and not include a single sentence about how to address shin splints? Rubbish!
Published 29 days ago by Kristie Hilgedick
THE ABSOLUTE BEST RESOURCE FOR FEMALE RUNNERS OF ALL LEVELS!!!!! Dr. Karp's expertise and knowledge into the world of running, physiology and mechanics behind it surpasses even the most avid runner's expectations and knowledge. Read more
Published 3 months ago by Erin J. Morgart
Great info for the middle aged runner I'm one of the oldest women (48) in my running group and am experiencing changes my friends are not. Read more
Published 4 months ago by Wendy Foster
just ok I thought this book was very dated. I will look for a more up-to-date written book in the future. Disappointed...
Published 6 months ago by D. Ivy
Solid reference; good practical guide A useful reference for women runners of all ages. Strong content on nutrition, hormones, as well as speed, flexibility, and strength training. Read more
Published 10 months ago by Anraku
GREAT book! I love it. Well worth the time and money. Many helpful tips and suggestions. Well written and sourced. Highly recommended.
Published 12 months ago by Bonnie Gaztambide
Women Runners Biomechanics The book is based upon the experience and research of exercise physiologist, running and fitness expert Jason Karp and family practice and sports medicine physician Carolyn Smith. Read more
Published 12 months ago by Jill Bemis
very informative A must for women who want to start or better their running program! Dr. Karp makes it very clear when it is the best times to train regarding yourcycle. Read more
Published 13 months ago by Godelieve Babey
A disappointment This book did not give much information on how to improve running performance for woman.It gave a lot of biological background but not much practical information.
Published 14 months ago by Lakshmi Reguna
The Ultimate Beginners Running Guide: The Key To Running Inspired by Ryan Robert Kindle Edition
Runner's World Complete Book of Women's Running: The Best Advice to Get Started, Stay Motivated, Lose  by Dagny Scott Barrios Kindle Edition
A Woman's Step-By-Step Guide To Running For Balanced Living: It's About More Than Being Skinny by Little Pearl Kindle Edition

value: Amazon.com, Inc. ( AM-ə-zon) is an American multinational conglomerate which focuses on e-commerce, cloud computing, digital streaming, and artificial intelligence.


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cell biology - What does substrate mean? - Biology Stack Exchange
I have been reading some literature on measurements related to biofilms.
In some articles the word "substrate" seems to stand for the material on which a biofilm is growing. In other articles, it seems to stand for the nutrients that are freely floating in (say water) where the biofilm is growing, and which then diffuse into the biofilm and which it uses to grow.
Have I misunderstood something or are both of these meanings in active use? Is there a disciplinary or some other difference that determines who uses which term?
The review article [1] uses substrate to mean freely floating nutrietnts. Also, searching for "substrate loading" or "substrate loading rate" or such (on Google scholar) gives examples of substrate as something that is fed to the biofilm.
For example Wikipedia uses the other meaning of substrate: https://en.wikipedia.org/wiki/Substrate . Scientific literature with this meaning can be related to how easily biofilms detach from a given material in the presence of shear forces.
[1] Harald Horn and Susanne Lackner. Modeling of biofilm systems: A review. In Kai Muffler and Roland Ulber, editors, Productive Biofilms, pages 53–76. Springer International Publishing, Cham, 2014.
cell-biology terminology biofilms
edited May 9 at 7:32
$\begingroup$ Latin: sub- underneath and stratum = layer... The under-layer literally, the base layer. $\endgroup$ – com.prehensible May 7 at 14:40
A substrate is an underlying substance or layer, or less strictly, the medium within or upon which an organism grows. For instance, you can have a filamentous fungus grow on a solid medium (e.g. on an agar plate) or in liquid medium (e.g. in a shaken flask containing a solution) and its substrate would be the contents of the agar or solution. It's nothing more fancy than that.
For instance, you could design 4 growth conditions for a strain of fungus.
Case in point, a hypothetical table could look like this:
*Substrate*
Wheat straw     Sugar beet pulp
Liquid         1   |   2
*Medium*             -----------------
Agar          3   |   4
$\begingroup$ What is the interpretation of all the "substrate loading rate"s, then? Are they simply misusing the terminology? $\endgroup$ – Tommi Brander May 7 at 19:13
$\begingroup$ @TommiBrander, no they are not misusing "substrate". Notice there are more words in the phrase "substrate loading rate". The phrase is referring to the the rate at which nutrients are loaded into the substrate. $\endgroup$ – mgkrebbs May 7 at 19:52
$\begingroup$ I edited in an explicit reference to a review article where "substrate" explicitly means diffusing nutrients, rather than the meaning mentioned here. $\endgroup$ – Tommi Brander May 9 at 7:34
$\begingroup$ The nutrient can be the substrate. Leaves are a substrate for leaf-eating caterpillars. The skin of an orange is a substrate for mold. In these examples you'd use the word substrate rather than medium. As with all language, it doesn't help to be too pedantic about dictionary definition. The word 'nutrient' is also fuzzy but I would advise against opening a thread about the meaning of nutrient. Happy sciencing! $\endgroup$ – S Pr May 9 at 9:25
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