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Patent US5754139 - Method and intelligent digital beam forming system responsive to traffic demand - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign inPatentsAn intelligent digital beam former (10) in conjunction with a satellite based array antenna (20) provides a plurality of dynamically controllable antenna beams (52) for communication with subscriber units (90) in response to demand for communication services. Geographic portions within the satellite's...http://www.google.com/patents/US5754139?utm_source=gb-gplus-sharePatent US5754139 - Method and intelligent digital beam forming system responsive to traffic demandAdvanced Patent SearchTry the new Google Patents, with machine-classified Google Scholar results, and Japanese and South Korean patents.Publication numberUS5754139 APublication typeGrantApplication numberUS 08/739,529Publication dateMay 19, 1998Filing dateOct 30, 1996Priority dateOct 30, 1996Fee statusPaidAlso published asCA2217805A1, CA2217805C, DE19747065A1, DE19747065B4Publication number08739529, 739529, US 5754139 A, US 5754139A, US-A-5754139, US5754139 A, US5754139AInventorsRandy Lee Turcotte, Stephen Chih-Hung Ma, Sergio AguirreOriginal AssigneeMotorola, Inc.Export CitationBiBTeX, EndNote, RefManPatent Citations (6), Referenced by (125), Classifications (8), Legal Events (6) External Links: USPTO, USPTO Assignment, EspacenetMethod and intelligent digital beam forming system responsive to traffic demand
Patent CitationsCited PatentFiling datePublication dateApplicantTitleUS3737899 *Feb 1, 1971Jun 5, 1973Raytheon CoPhased array antenna controllerUS4845504 *Apr 8, 1987Jul 4, 1989M/A-Com, Inc.Mobile radio network for nationwide communicationsUS4996532 *Dec 13, 1989Feb 26, 1991Mitsubishi Denki Kabushiki KaishaDigital beam forming radar systemUS5059966 *Feb 8, 1990Oct 22, 1991Mitsubishi Denki Kabushiki KaishaSynthetic aperture radar systemUS5086302 *Apr 10, 1991Feb 4, 1992Allied-Signal Inc.Fault isolation in a Butler matrix fed circular phased array antennaUS5392257 *Aug 23, 1993Feb 21, 1995Westinghouse Electric Corp.Sonar receiver with improved time varied gain correction* Cited by examinerReferenced byCiting PatentFiling datePublication dateApplicantTitleUS5926130 *Jul 10, 1998Jul 20, 1999Hughes Electronics CorporationDigital spacecraft antenna tracking systemUS5936569 *Dec 2, 1997Aug 10, 1999Nokia Telecommunications OyMethod and arrangement for adjusting antenna patternUS5936577 *Oct 17, 1997Aug 10, 1999Kabushiki Kaisha ToshibaAdaptive antennaUS5943010 *Nov 12, 1997Aug 24, 1999Ail Systems, Inc.Direct digital synthesizer driven phased array antennaUS5966094 *Oct 29, 1997Oct 12, 1999Northern Telecom LimitedBase station antenna arrangementUS5977907 *Feb 2, 1998Nov 2, 1999Motorola, Inc.Method and system for antenna pattern synthesis based on geographical distribution of subscribersUS6205319 *Sep 18, 1998Mar 20, 2001Trw Inc.Dual phased-array payload conceptUS6377558 *Apr 6, 1998Apr 23, 2002Ericsson Inc.Multi-signal transmit array with low intermodulationUS6448930Oct 13, 2000Sep 10, 2002Andrew CorporationIndoor antennaUS6490448Dec 10, 1999Dec 3, 2002Motorola, Inc.Snap to grid variable beam size digital beamforming systemUS6496707 *Jan 23, 1998Dec 17, 2002Lucent Technologies Inc.System and method for optimizing a wireless network by adaptive configuration of base stations and wireless terminalsUS6546256 *Feb 1, 1999Apr 8, 2003Ksi Inc.Robust, efficient, location-related measurementUS6583763Apr 26, 1999Jun 24, 2003Andrew CorporationAntenna structure and installationUS6597325Oct 21, 1999Jul 22, 2003Andrew CorporationTransmit/receive distributed antenna systemsUS6621469May 1, 2001Sep 16, 2003Andrew CorporationTransmit/receive distributed antenna systemsUS6636726Jun 21, 2000Oct 21, 2003Telefonaktiebolaget Lm Ericsson (Publ)Method and arrangement for radio communicationUS6690328Mar 12, 2001Feb 10, 2004Andrew CorporationAntenna structure and installationUS6697619Dec 10, 1999Feb 24, 2004Motorola, Inc.Digital beamforming acquisition systemUS6731904Jul 20, 1999May 4, 2004Andrew CorporationSide-to-side repeaterUS6745003Jan 14, 2000Jun 1, 2004Andrew CorporationAdaptive cancellation for wireless repeatersUS6756937Jun 6, 2000Jun 29, 2004The Directv Group, Inc.Stratospheric platforms based mobile communications architectureUS6762718Nov 7, 2002Jul 13, 2004The Directtv Group, Inc.Wavefront-projection beamformerUS6763242Sep 14, 2000Jul 13, 2004The Directv Group, Inc.Resource assignment system and method for determining the sameUS6778507 *Sep 1, 1999Aug 17, 2004Qualcomm IncorporatedMethod and apparatus for beamforming in a wireless communication systemUS6781555Mar 5, 2002Aug 24, 2004The Directv Group, Inc.Multi-beam antenna communication system and methodUS6812905Oct 31, 2001Nov 2, 2004Andrew CorporationIntegrated active antenna for multi-carrier applicationsUS6844863Sep 27, 2002Jan 18, 2005Andrew CorporationActive antenna with interleaved arrays of antenna elementsUS6868269Aug 28, 2000Mar 15, 2005The Directv Group, Inc.Integrating coverage areas of multiple transponder platformsUS6885343Sep 26, 2002Apr 26, 2005Andrew CorporationStripline parallel-series-fed proximity-coupled cavity backed patch antenna arrayUS6891813Dec 12, 2000May 10, 2005The Directv Group, Inc.Dynamic cell CDMA code assignment system and methodUS6895217Aug 21, 2000May 17, 2005The Directv Group, Inc.Stratospheric-based communication system for mobile users having adaptive interference rejectionUS6906681Sep 27, 2002Jun 14, 2005Andrew CorporationMulticarrier distributed active antennaUS6914557Sep 5, 2001Jul 5, 2005The Directv Group, Inc.Micro cell architecture for mobile user tracking communication systemUS6934511Oct 23, 2000Aug 23, 2005Andrew CorporationIntegrated repeaterUS6952580Dec 12, 2000Oct 4, 2005The Directv Group, Inc.Multiple link internet protocol mobile communications system and method thereforUS6952587 *Jan 28, 2002Oct 4, 2005Visteon Global Technologies, Inc.Antenna beam steering responsive to receiver and broadcast transmitterUS6972622May 12, 2003Dec 6, 2005Andrew CorporationOptimization of error loops in distributed power amplifiersUS6983174Sep 18, 2002Jan 3, 2006Andrew CorporationDistributed active transmit and/or receive antennaUS7027454 *Nov 13, 2001Apr 11, 2006Ericcson Inc.Multi-signal transmit array with low intermodulationUS7053838Jan 14, 2004May 30, 2006Andrew CorporationAntenna structure and installationUS7062246 *Jun 5, 2001Jun 13, 2006Motorola. Inc.Adaptive antenna array and method of controlling operation thereofUS7068616Apr 20, 2001Jun 27, 2006The Directv Group, Inc.Multiple dynamic connectivity for satellite communications systemsUS7103317 *Sep 28, 2001Sep 5, 2006The Directv Group, Inc.Communication system using multiple link terminals for aircraftUS7129879 *Jul 12, 2005Oct 31, 2006Analog Devices, Inc.Method of and apparatus for characterizing an analog to digital converterUS7164725 *Mar 8, 2001Jan 16, 2007Motorola, Inc.Method and apparatus for antenna array beamformingUS7167704Mar 24, 2006Jan 23, 2007The Directv Group, Inc.Communication system using multiple link terminals for aircraftUS7181162Sep 28, 2001Feb 20, 2007The Directv Group, Inc.Communication system using multiple link terminalsUS7187949May 15, 2001Mar 6, 2007The Directv Group, Inc.Multiple basestation communication system having adaptive antennasUS7194270Sep 30, 2003Mar 20, 2007Northrop Grumman CorporationDynamic beam width selection for non-uniform density multiple access cellsUS7257418Aug 31, 2000Aug 14, 2007The Directv Group, Inc.Rapid user acquisition by a ground-based beamformerUS7280848Sep 30, 2002Oct 9, 2007Andrew CorporationActive array antenna and system for beamformingUS7317916Sep 14, 2000Jan 8, 2008The Directv Group, Inc.Stratospheric-based communication system for mobile users using additional phased array elements for interference rejectionUS7339520Feb 4, 2000Mar 4, 2008The Directv Group, Inc.Phased array terminal for equatorial satellite constellationsUS7340259Jan 17, 2003Mar 4, 2008Ksi Inc.Robust, efficient, localization systemUS7369847Sep 14, 2000May 6, 2008The Directv Group, Inc.Fixed cell communication system with reduced interferenceUS7372824 *Mar 31, 2003May 13, 2008Megawave Audio LlcSatellite receiver/router, system, and method of useUS7400857Sep 28, 2001Jul 15, 2008The Directv Group, Inc.Communication system using multiple link terminalsUS7623868Nov 24, 2009Andrew LlcMulti-band wireless access point comprising coextensive coverage regionsUS7792068Mar 31, 2003Sep 7, 2010Robert Iii RoswellSatellite receiver/router, system, and method of useUS7809403May 15, 2001Oct 5, 2010The Directv Group, Inc.Stratospheric platforms communication system using adaptive antennasUS7929984Apr 19, 2011The Directv Group, Inc.Multiple basestation communication system having adaptive antennasUS7962174Jun 14, 2011Andrew LlcTransceiver architecture and method for wireless base-stationsUS8010042Aug 30, 2011Andrew LlcRepeaters for wireless communication systemsUS8068827 *Nov 29, 2011Viasat, Inc.Non-interfering utilization of non-geostationary satellite frequency band for geostationary satellite communicationUS8145123Nov 10, 2009Mar 27, 2012Mitsubishi Electric CorporationSatellite communication system and method for dividing the coverage area thereofUS8213929Jul 3, 2012Viasat, Inc.Non-interfering utilization of non-geostationary satellite frequency band for geostationary satellite communicationUS8339307 *Feb 29, 2008Dec 25, 2012Astrium LimitedSatellite beam-pointing error correction in digital beam-forming architectureUS8358970Jan 22, 2013Andrew CorporationRepeaters for wireless communication systemsUS8374292Oct 29, 2010Feb 12, 2013Com Dev International Ltd.System and method for decoding automatic identification system signalsUS8396513Mar 12, 2013The Directv Group, Inc.Communication system for mobile users using adaptive antennaUS8542785Jul 2, 2009Sep 24, 2013Mitsubishi Electric CorporationCommunication apparatus and communication systemUS8558734 *Jul 15, 2010Oct 15, 2013Gregory Hubert PiesingerThree dimensional radar antenna method and apparatusUS8630581Jan 18, 2013Jan 14, 2014Andrew LlcRepeaters for wireless communication systemsUS8780788Sep 25, 2009Jul 15, 2014Com Dev International Ltd.Systems and methods for decoding automatic identification system signalsUS8897769May 25, 2012Nov 25, 2014Viasat, Inc.Non-interfering utilization of non-geostationary satellite frequency band for geostationary satellite communicationUS8971796Jan 13, 2014Mar 3, 2015Andrew LlcRepeaters for wireless communication systemsUS9015567Apr 12, 2012Apr 21, 2015Com Dev International Ltd.Methods and systems for consistency checking and anomaly detection in automatic identification system signal dataUS9287961 *Feb 21, 2013Mar 15, 2016Spatial Digital Systems, Inc.Receive only smart ground-terminal antenna for geostationary satellites in slightly inclined orbitsUS9331774Jun 9, 2010May 3, 2016Exactearth Ltd.Systems and methods for segmenting a satellite field of view for detecting radio frequency signalsUS20020050946 *Feb 4, 2000May 2, 2002Chang Donald C. D.An improved phased array terminal for equatorial satellite constellationsUS20020072332 *Sep 28, 2001Jun 13, 2002Hughes Electronics CorporationCommunication system using multiple link terminals for aircraftUS20020072374 *Sep 28, 2001Jun 13, 2002Hughes Electronics CorporationCommunication system using multiple link terminalsUS20020073437 *Sep 28, 2001Jun 13, 2002Hughes Electronics CorporationTelevision distribution system using multiple linksUS20020080732 *Dec 12, 2000Jun 27, 2002Hughes Electronics CorporationDynamic cell CDMA code assignment system and methodUS20020081969 *Sep 28, 2001Jun 27, 2002Hughes Electronics CorporationCommunication system using multiple link terminalsUS20020115452 *Jan 28, 2002Aug 22, 2002Whikehart J. WilliamAntenna beam steering responsive to receiver and broadcast trasmitterUS20020118654 *Apr 20, 2001Aug 29, 2002Chang Donald C.D.Multiple dynamic connectivity for satellite communications systemsUS20020126042 *Sep 5, 2001Sep 12, 2002Hughes Electronics CorporationMicro cell architecture for mobile user tracking communication systemUS20020132643 *May 15, 2001Sep 19, 2002Chang Donald C.D.Multiple basestation communication system having adaptive antennasUS20030100039 *Apr 27, 2001May 29, 2003Duecker KlausNovel human phospholipase c delta 5US20030129996 *Jan 17, 2003Jul 10, 2003Ksi Inc.Robust, efficient, localization systemUS20040052227 *Sep 16, 2002Mar 18, 2004Andrew CorporationMulti-band wireless access pointUS20040066352 *Sep 27, 2002Apr 8, 2004Andrew CorporationMulticarrier distributed active antennaUS20040072570 *Sep 30, 2003Apr 15, 2004Smith Ronald P.Dynamic beam width selection for non-uniform density multiple access cellsUS20040136333 *Mar 31, 2003Jul 15, 2004Roswell RobertSatellite receiver/router, system, and method of useUS20040192392 *Sep 18, 2002Sep 30, 2004Andrew CorporationDistributed active transmit and/or receive antennaUS20040203804 *Jan 3, 2003Oct 14, 2004Andrew CorporationReduction of intermodualtion product interference in a network having sectorized access pointsUS20040204098 *Jun 5, 2001Oct 14, 2004Ray OwenAdaptive antenna array and method of controlling operation thereofUS20040204109 *Sep 30, 2002Oct 14, 2004Andrew CorporationActive array antenna and system for beamformingUS20040227570 *May 12, 2003Nov 18, 2004Andrew CorporationOptimization of error loops in distributed power amplifiersUS20050099359 *Jan 14, 2004May 12, 2005Andrew CorporationAntenna structure and installationUS20050099969 *Mar 31, 2003May 12, 2005Roberts Roswell IiiSatellite receiver/router, system, and method of useUS20060178143 *Mar 24, 2006Aug 10, 2006Chang Donald C DCommunication system using multiple link terminals for aircraftUS20080014866 *Jul 12, 2006Jan 17, 2008Lipowski Joseph TTransceiver architecture and method for wireless base-stationsUS20080161015 *Jan 2, 2008Jul 3, 2008Trueposition, Inc.Robust, Efficient, Localization SystemUS20090093213 *Oct 9, 2008Apr 9, 2009Viasat, Inc.Non-interfering utilization of non-geostationary satellite frequency band for geostationary satellite communicationUS20100029197 *Aug 10, 2009Feb 4, 2010Andrew LlcRepeaters for wireless communication systemsUS20100231442 *Feb 29, 2008Sep 16, 2010Anthony Duncan CraigSatellite beam-pointing error correction in digital beam-forming architectureUS20110075602 *Sep 25, 2009Mar 31, 2011Com Dev International Ltd.Systems and methods for decoding automatic identification system signalsUS20110206155 *Jul 2, 2009Aug 25, 2011Mitsubishi Electric CorporationCommunication apparatus and communication systemUS20110212681 *Nov 10, 2009Sep 1, 2011Mitsubishi Electric CorporationSatellite communication system and method for dividing the coverage area thereofUS20130222184 *Feb 21, 2013Aug 29, 2013Donald C.D. ChangReceive only smart ground-terminal antenna for geostationary satellites in slightly inclined orbitsEP1093242A1 *Oct 11, 2000Apr 18, 2001TRW Inc.Dynamic beam width selection for non-uniform density multiple access cellsEP1107476A2 *Nov 20, 2000Jun 13, 2001Motorola, Inc.Method and apparatus for controlling antenna beams within a cellular communication systemEP1526605A1 *Oct 22, 2004Apr 27, 2005Itt Manufacturing Enterprises, Inc.Apparatus and method for multi-beam, multi-signal transmission by an active phased array antennaEP2262126A3 *Aug 31, 2000Sep 17, 2014Qualcomm IncorporatedMethod and apparatus for beamforming in a wireless communication systemEP2880462A4 *Jul 22, 2013Apr 6, 2016Elta Systems LtdTransponder deviceWO2000079699A1 *Jun 13, 2000Dec 28, 2000Telefonaktiebolaget L M EricssonMethod and arrangement for radio communication with an electrically controlled antennaWO2001011802A1 *Aug 8, 2000Feb 15, 2001Ico Services Ltd.Satellite data systemWO2001013543A1 *Aug 16, 2000Feb 22, 2001Qualcomm IncorporatedSatellite communication system using wide fixed beams and narrow steerable beamsWO2001017131A1 *Aug 31, 2000Mar 8, 2001Qualcomm IncorporatedMethod and apparatus for beamforming in a wireless communication systemWO2001041531A2 *Oct 17, 2000Jun 14, 2001Motorola, Inc.Digital beamforming acquisition systemWO2001041531A3 *Oct 17, 2000Nov 29, 2001Motorola IncDigital beamforming acquisition systemWO2001041548A2 *Nov 22, 2000Jun 14, 2001Motorola, Inc.Variable beam size digital beamforming systemWO2001041548A3 *Nov 22, 2000Jan 31, 2002Motorola IncVariable beam size digital beamforming system* Cited by examinerClassifications U.S. Classification342/373, 342/372, 342/374International ClassificationH04B7/15, H04B7/204, H01Q3/26Cooperative ClassificationH04B7/2041European ClassificationH04B7/204BLegal EventsDateCodeEventDescriptionOct 30, 1996ASAssignmentOwner name: MOTOROLA, INC., ILLINOISFree format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:TURCOTTE, RANDY LEE;MA, STEPHEN CHIH-HUNG;AGUIRRE, SERGIO;REEL/FRAME:008287/0994;SIGNING DATES FROM 19961021 TO 19961022Sep 28, 2001FPAYFee paymentYear of fee payment: 4Sep 28, 2005FPAYFee paymentYear of fee payment: 8Sep 12, 2008ASAssignmentOwner name: TORSAL TECHNOLOGY GROUP LTD. 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Patent US7076656 - Methods and apparatus for providing efficient password-authenticated key ... - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign inPatentsA secure protocol is provided which uses a Diffie-Hellman type shared secret, but modified such that the two parties may authenticate each other using a shared password. In accordance with the invention, a party generates the Diffie-Hellman value gx and combines it with a function of at least the password...http://www.google.com/patents/US7076656?utm_source=gb-gplus-sharePatent US7076656 - Methods and apparatus for providing efficient password-authenticated key exchangeAdvanced Patent SearchPublication numberUS7076656 B2Publication typeGrantApplication numberUS 09/827,227Publication dateJul 11, 2006Filing dateApr 5, 2001Priority dateApr 5, 2001Fee statusPaidAlso published asCA2376947A1, CA2376947C, DE60200496D1, DE60200496T2, EP1248408A2, EP1248408A3, EP1248408B1, US20020194478Publication number09827227, 827227, US 7076656 B2, US 7076656B2, US-B2-7076656, US7076656 B2, US7076656B2InventorsPhilip D. MacKenzieOriginal AssigneeLucent Technologies Inc.Export CitationBiBTeX, EndNote, RefManPatent Citations (17), Non-Patent Citations (23), Referenced by (32), Classifications (8), Legal Events (6) External Links: USPTO, USPTO Assignment, EspacenetMethods and apparatus for providing efficient password-authenticated key exchange
Patent CitationsCited PatentFiling datePublication dateApplicantTitleUS4956863 *Apr 17, 1989Sep 11, 1990Trw Inc.Cryptographic method and apparatus for public key exchange with authenticationUS5241599Oct 2, 1991Aug 31, 1993At&T Bell LaboratoriesCryptographic protocol for secure communicationsUS5351293 *Feb 1, 1993Sep 27, 1994Wave Systems Corp.System method and apparatus for authenticating an encrypted signalUS5440635Aug 23, 1993Aug 8, 1995At&T Corp.Cryptographic protocol for remote authenticationUS5450493 *Dec 29, 1993Sep 12, 1995At&T Corp.Secure communication method and apparatusUS5602917 *Dec 30, 1994Feb 11, 1997Lucent Technologies Inc.Method for secure session key generationUS6028937 *Oct 9, 1996Feb 22, 2000Matsushita Electric Industrial Co., LtdCommunication device which performs two-way encryption authentication in challenge response formatUS6226383 *Mar 25, 1997May 1, 2001Integrity Sciences, Inc.Cryptographic methods for remote authenticationUS6539479 *Jul 14, 1998Mar 25, 2003The Board Of Trustees Of The Leland Stanford Junior UniversitySystem and method for securely logging onto a remotely located computerUS6829356 *May 17, 2000Dec 7, 2004Verisign, Inc.Server-assisted regeneration of a strong secret from a weak secretUS6910129 *Mar 3, 2000Jun 21, 2005Kent Ridge Digital LabsRemote authentication based on exchanging signals representing biometrics informationUS6993651 *Dec 7, 2000Jan 31, 2006Hewlett-Packard Development Company, L.P.Security protocolUS20010055388 *Mar 12, 2001Dec 27, 2001Kaliski Burton S.Server-assisted regeneration of a strong secret from a weak secretUS20040128517 *Dec 31, 2002Jul 1, 2004Drews Paul C.Methods and apparatus for finding a shared secret without compromising non-shared secretsEP1134929A1Oct 23, 2000Sep 19, 2001Lucent Technologies Inc.Secure mutual network authentication and key exchange protocolEP1248408A2 *Mar 22, 2002Oct 9, 2002Lucent Technologies Inc.Methods and apparatus for providing efficient password-authenticated key exchangeWO2005055512A2 *Dec 1, 2004Jun 16, 2005The Regents Of The University Of CaliforniaCryptography for secure dynamic group communications* Cited by examinerNon-Patent CitationsReference1 *Bhattacharya et al, Improving the Diffie-Hellman Secure Key Exchange, 2005, IEEE, vol. 1, pp. 193-197.2D. Jablon, "Strong Password-Only Authenticated Key Exchange," ACM Computer Communications Review, ACM SIGCOMM, pp. 1-22, 1996.3D.P. Jablon, "Extended Password Key Exchange Protocols Immune to Dictionary Attack," WETICE Workshop on Enterprise Security, pp. 1-8, 1997.4FIPS 180-1, "Secure Hash Standard," Federal Information Processing Standards Publication 180-1, pp. 1-21, 1995.5H. Dobbertin et al., RIPEMD-160: a Strengthened Version of RIPEMD, Fast Software Encryption, 3rd Intl. Workshop, pp. 1-13, 1996.6 *Li Gong, T. Mark A. Lomas, Roger M. Needham, Jerome H. Saltzer, Protecting Poorly Chosen Secrets from Guessing Attacks (1993) IEEE Journal on Selected Areas in Communications.7M. Bellare et al., "Authenticated Key Exchange Secure Against Dictionary Attacks," Advances in Cryptology, pp. 1-16, Eurocrypt 2000.8M. Steiner et al., "Refinement and Extension of Encrypted Key Exchange," ACM Operating System Review, pp. 1-9, 1994.9 *Oorcshot et al. On Diffie-Hellman Key Agreement with Short Exponents. Feb. 19, 1996, Proc. of Eurocrypt '96, Springer-Verlag LNCS.10R.L. Rivest et al., "A Method for Obtaining Digital Signatures and Public-Key Cryptosystems," Communications of the ACM, vol. 21, No. 2, pp. 120-126, 1978.11S. Patel, "Number Theoretic Attacks on Secure Password Schemes," Proceedings of the IEEE Symposium on Research in Security and Privacy, pp. 236-247, 1997.12S.M. Bellovin et al., "Augmented Encrypted Key Exchange: A Password-Based Protocol Secure Against Dictionary Attacks and Password File Compromise," Proceedings of the First Annual Conference on Computer and Communications Security, pp. 1-7, 1993.13S.M. Bellovin et al., "Encrypted Key Exchange: Password-Based Protocols Secure Against Dictionary Attacks," Proceedings of the IEEE Symposium on Research in Security and Privacy, pp. 72-84, 1992.14 *Schneier, Bruce, Applied Cryptography 1996 John Wiley & Sons, 2nd Edition.15 *Seo et al, Simple Authenticated Key Agreement Algorithm, Jun. 1999, IEEE, vol. 35 Issue 13, pp. 1073-1074.16Stefan Lucks, "Open Key Exchange: How to Defeat Dictionary Attacks Without Encrypting Public Keys," Security Protocol Workshop, pp. 1-12, 1997.17T. Wu, "The Secure Remote Password Protocol," Proceedings of the 1998 Internet Society Symposium on Network and Distributed System Security, pp. 1-17, 1997.18U.S. Appl. No. 09/353,468, filed Jul. 13, 1999, P.D. MacKenzie et al., "Secure Mutual Network Authentication Protocol (SNAPI)."19U.S. Appl. No. 09/638,320, filed Aug. 14, 2000, V.V. Boyko et al., "Secure Mutual Network Authentication and Key Exchange Protocol."20V. Boyko et al., "Provably Secure Password-Authenticated Key Exchange Using Diffie-Hellman," Advances in Cryptology, Eurocrypt 2000, pp. 156-171, 2000.21W. Diffie et al., "New Directions in Cryptography," IEEE Transactions on Information Theory, vol. IT 22, No. 6, pp. 644-654, 1976.22 *Wang et al, Supervising Secret-Key Agreements in a Level-Based Hierarchy, 2004, IEEE, vol. 1, pp. 309-314.23 *Yuh-Min Tseng, A Robust Multi-Party Key Agreement Protocol Resistant to Malicious Participants, May 2005, The Computer Journal, vol. 48 No. 4, pp. 480-487.* Cited by examinerReferenced byCiting PatentFiling datePublication dateApplicantTitleUS7284127 *Jun 24, 2003Oct 16, 2007Telefonktiebolaget Lm Ericsson (Publ)Secure communicationsUS7305556 *Dec 5, 2001Dec 4, 2007Canon Kabushiki KaishaSecure printing with authenticated printer keyUS7370070 *Sep 1, 2004May 6, 2008Canon Kabushiki KaishaData sharing method, request processing method, program, and apparatusUS7502930 *Aug 22, 2007Mar 10, 2009Telefonaktiebolaget L M Ericsson (Publ)Secure communicationsUS7522723Jul 10, 2008Apr 21, 2009Cheman ShaikPassword self encryption method and system and encryption by keys generated from personal secret informationUS7650494Jul 2, 2003Jan 19, 2010Hewlett-Packard Development Company, L.P.Method and apparatus for use in relation to verifying an association between two partiesUS7764795 *Oct 20, 2004Jul 27, 2010Oracle International CorporationKey-exchange protocol using a password-derived primeUS7814320 *Jul 14, 2006Oct 12, 2010Ntt Docomo, Inc.Cryptographic authentication, and/or establishment of shared cryptographic keys, using a signing key encrypted with a non-one-time-pad encryption, including (but not limited to) techniques with improved security against malleability attacksUS8023647Sep 20, 2011Cheman ShaikPassword self encryption method and system and encryption by keys generated from personal secret informationUS8090947Jan 3, 2012Certicom Corp.Key agreement and transport protocol with implicit signaturesUS8209533Dec 20, 2007Jun 26, 2012Certicom Corp.Key agreement and transport protocolUS8351602Jan 8, 2013Industrial Technology Research InstituteDual-mode wireless sensor network system and key establishing method and event processing method thereofUS8433918 *Oct 1, 2010Apr 30, 2013Texas Instruments IncorporatedMethods and systems for improving the security of password-based authentication protocols for IEEE 802.11 networksUS8578165Feb 1, 2012Nov 5, 2013Certicom Corp.Key agreement and transport protocolUS8745715 *Apr 16, 2003Jun 3, 2014Telefonaktiebolaget Lm Ericsson (Publ)Password-based authentication system and method in group networkUS8831214Mar 12, 2009Sep 9, 2014Cheman ShaikPassword self encryption method and system and encryption by keys generated from personal secret informationUS8892890Sep 27, 2013Nov 18, 2014Certicom Corp.Key agreement and transport protocolUS20030105963 *Dec 5, 2001Jun 5, 2003Slick Royce E.Secure printing with authenticated printer keyUS20040083368 *Jun 24, 2003Apr 29, 2004Christian GehrmannSecure communicationsUS20040123098 *Jul 2, 2003Jun 24, 2004Ligun ChenMethod and apparatus for use in relation to verifying an association between two partiesUS20050089173 *Jul 15, 2004Apr 28, 2005Harrison Keith A.Trusted authority for identifier-based cryptographyUS20050102516 *Sep 1, 2004May 12, 2005Canon Kabushiki KaishaData sharing method, request processing method, program, and apparatusUS20060085643 *Oct 20, 2004Apr 20, 2006Oracle International CorporationKey-exchange protocol using a password-derived primeUS20060236384 *Apr 16, 2003Oct 19, 2006Fredrik LindholmAuthentication methodUS20070067629 *Jul 14, 2006Mar 22, 2007Philip MackenzieCryptographic authentication, and/or establishment of shared cryptographic keys, using a signing key encrypted with a non-one-time-pad encryption, including (but not limited to) techniques with improved security against malleability attacksUS20070288753 *Aug 22, 2007Dec 13, 2007Christian GehrmannSecure communicationsUS20080162938 *Dec 20, 2007Jul 3, 2008Marinus StruikKey agreement and transport protocolUS20090141899 *Feb 27, 2008Jun 4, 2009Industrial Technology Research InstituteDual-mode wireless sensor network system and key establishing method and event processing method thereofUS20100281259 *Jul 15, 2010Nov 4, 2010Certicom Corp.Key agreement and transport protocol with implicit signaturesUS20110087884 *Oct 1, 2010Apr 14, 2011Texas Instruments IncorporatedMethods and Systems for Improving the Security of Password-Based Authentication Protocols for IEEE 802.11 NetworksWO2007011897A2 *Jul 17, 2006Jan 25, 2007Ntt Docomo Inc.Cryptographic authentication, and/or establishment of shared cryptographic keys, using a signing key encrypted with a non-one-time-pad encryption, including (but not limited to) techniques with improved security against malleability attacksWO2007011897A3 *Jul 17, 2006Jul 12, 2007Craig B GentryCryptographic authentication, and/or establishment of shared cryptographic keys, using a signing key encrypted with a non-one-time-pad encryption, including (but not limited to) techniques with improved security against malleability attacks* Cited by examinerClassifications U.S. Classification713/171, 713/169, 380/28International ClassificationH04L9/08, H04L9/28, H04L9/32Cooperative ClassificationH04L9/0844European ClassificationH04L9/08F4B2Legal EventsDateCodeEventDescriptionJun 21, 2001ASAssignmentOwner name: LUCENT TECHNOLOGIES INC., NEW JERSEYFree format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:MACKENZIE, PHILIP D.;REEL/FRAME:011927/0577Effective date: 20010424Jan 8, 2010FPAYFee paymentYear of fee payment: 4Mar 7, 2013ASAssignmentFree format text: SECURITY INTEREST;ASSIGNOR:ALCATEL-LUCENT USA INC.;REEL/FRAME:030510/0627Owner name: CREDIT SUISSE AG, NEW YORKEffective date: 20130130Jan 3, 2014FPAYFee paymentYear of fee payment: 8May 13, 2014ASAssignmentOwner name: ALCATEL-LUCENT USA INC., NEW JERSEYFree format text: MERGER;ASSIGNOR:LUCENT TECHNOLOGIES INC.;REEL/FRAME:032891/0562Effective date: 20081101Oct 9, 2014ASAssignmentOwner name: ALCATEL-LUCENT USA INC., NEW JERSEYFree format text: RELEASE BY SECURED PARTY;ASSIGNOR:CREDIT SUISSE 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Anchor Hocking Depression Glassware | eBay Please enable JavaScript Our new search experience requires JavaScript to be enabled. Please enable JavaScript on your browser, then try again.
Skip to main contenteBayShop by categoryEnter your search keywordAnchor Hocking└ Depression└ Glassware└ Glass└ Pottery & GlassAll CategoriesAntiquesArtBabyBooksBusiness & IndustrialCameras & PhotoCell Phones & AccessoriesClothing, Shoes & AccessoriesCoins & Paper MoneyCollectiblesComputers/Tablets & NetworkingConsumer ElectronicsCraftsDolls & BearsDVDs & MovieseBay MotorsEntertainment MemorabiliaGift Cards & CouponsHealth & BeautyHome & GardenJewelry & WatchesMusicMusical Instruments & GearPet SuppliesPottery & GlassReal EstateSpecialty ServicesSporting GoodsSports Mem, Cards & Fan ShopStampsTickets & ExperiencesToys & HobbiesTravelVideo Games & ConsolesEverything ElseAdvanced or register':' style="margin-right:3px">Hi -User-!'.replace(/-User-/,escape(a)))+"")}catch(b){document.write("")}})();Hi (Sign in to bid or buy)Daily DealsGift CardsSellHelp & ContactMy eBayExpand My eBaySummaryBids/OffersWatch listWish listAll listsPurchase historySellingMy CollectionsFollowed searchesMessagesNotification Related: manhattan miss america pink depression glass green miss america miss america pink oyster and pearl depression glass open lace green cameo depression glass
in Anchor Hocking: Used Used
Large jade-ite round ribbed 12" bowl
Pair of Hocking Pink Depression Candle Stick/Votive Holders
Vintage Crystal Heavy Ice Cream Sundae Glass by Anchor Hocking
MANHANDLER STRONG1990s VTG ANCHOR HOCKING MANHATTAN REPRODUCTION 9pc PITCHER SET
Ca.193o DEPRESSION JAR Ex.CONDITIONED ORIGINAL TO ERA
Lenox Small Trinket Dish Vintage 3" Square with Gold Trim
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VINTAGE ANCHOR HOCKING IRIDESCENT CARNIVAL GLASS PIGGY BANK - 4.25" LONG 3" TALL
depression glass large pitcher with ice lip heavy glass with a great design
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value: This website is an American multinational e-commerce corporation based in San Jose, California, that facilitates consumer-to-consumer and business-to-consumer sales through its website.


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Patent US7643658 - Display arrangement including face detection - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign in<nobr>Advanced Patent Search</nobr>PatentsA display arrangement comprises an image display device having a first camera directed towards positions adopted by users viewing the display; one or more further cameras directed towards other respective locations; a face detector for detecting human faces in images captured by the cameras; and means...http://www.google.com/patents/US7643658?utm_source=gb-gplus-sharePatent US7643658 - Display arrangement including face detectionAdvanced Patent SearchPublication numberUS7643658 B2Publication typeGrantApplication numberUS 11/040,587Publication dateJan 5, 2010Filing dateJan 21, 2005Priority dateJan 23, 2004Fee statusPaidAlso published asEP1566788A2, US20050197923Publication number040587, 11040587, US 7643658 B2, US 7643658B2, US-B2-7643658, US7643658 B2, US7643658B2InventorsAndrew Roger Kilner, Victoria Sophia Jennings, Sebastian Aleksander Paszkowicz, Robert Mark Stefan Porter, Ratna Rambaruth, Clive Henry GillardOriginal AssigneeSony United Kingdom LimitedExport CitationBiBTeX, EndNote, RefManPatent Citations (29), Non-Patent Citations (1), Referenced by (23), Classifications (26), Legal Events (2) External Links: USPTO, USPTO Assignment, EspacenetDisplay arrangement including face detectionUS 7643658 B2Abstract A display arrangement comprises an image display device having a first camera directed towards positions adopted by users viewing the display; one or more further cameras directed towards other respective locations; a face detector for detecting human faces in images captured by the cameras; and means for detecting those faces which appear in images captured by both the first camera and at least one of the further cameras.
Patent CitationsCited PatentFiling datePublication dateApplicantTitleUS5331544 *Apr 23, 1992Jul 19, 1994A. C. Nielsen CompanyMarket research method and system for collecting retail store and shopper market research dataUS5966696 *Apr 14, 1998Oct 12, 1999InfovationSystem for tracking consumer exposure and for exposing consumers to different advertisementsUS6111517 *Dec 30, 1996Aug 29, 2000Visionics CorporationContinuous video monitoring using face recognition for access controlUS6185314 *Feb 6, 1998Feb 6, 2001Ncr CorporationSystem and method for matching image information to object model informationUS6246995 *May 29, 1998Jun 12, 2001Ncr CorporationProduct activity data collection systemUS6263088 *Feb 6, 1998Jul 17, 2001Ncr CorporationSystem and method for tracking movement of objects in a sceneUS6295367 *Feb 6, 1998Sep 25, 2001Emtera CorporationSystem and method for tracking movement of objects in a scene using correspondence graphsUS6404900 *Jan 14, 1999Jun 11, 2002Sharp Laboratories Of America, Inc.Method for robust human face tracking in presence of multiple personsUS6502076 *Jun 1, 1999Dec 31, 2002Ncr CorporationSystem and methods for determining and displaying product promotionsUS6647269 *Jul 5, 2001Nov 11, 2003TelcontarMethod and system for analyzing advertisements delivered to a mobile unitUS6793128 *Jun 18, 2001Sep 21, 2004Hewlett-Packard Development Company, L.P.Face photo storage systemUS6795808 *Oct 30, 2000Sep 21, 2004Koninklijke Philips Electronics N.V.User interface/entertainment device that simulates personal interaction and charges external database with relevant dataUS7283650 *Nov 26, 2003Oct 16, 2007Video Mining CorporationMethod and system for printing of automatically captured facial images augmented with promotional contentUS20020072952Dec 7, 2000Jun 13, 2002International Business Machines CorporationVisual and audible consumer reaction collectionUS20020075332 *Sep 22, 1999Jun 20, 2002Bradley Earl GeilfussSystems and methods for interactive product placementUS20020107729 *Feb 6, 2001Aug 8, 2002Catalina Marketing International, Inc.Method and system for timing promotions based on a prior receipt of promotionsUS20020178447 *Apr 3, 2002Nov 28, 2002Plotnick Michael A.Behavioral targeted advertisingUS20020184098 *May 8, 2002Dec 5, 2002Giraud Stephen G.Interactive promotional information communicating systemUS20020190119 *Jun 18, 2001Dec 19, 2002Huffman John W.Face photo storage systemUS20030001846 *Jan 3, 2001Jan 2, 2003Davis Marc E.Automatic personalized media creation systemUS20030018522 *Jul 20, 2001Jan 23, 2003Psc Scanning, Inc.Biometric system and method for identifying a customer upon entering a retail establishmentUS20030044046 *Aug 28, 2002Mar 6, 2003Yoshifumi NakamuraMethod and system for delivering monitored image signal of sbject to be monitoredUS20030088832 *Nov 2, 2001May 8, 2003Eastman Kodak CompanyMethod and apparatus for automatic selection and presentation of informationUS20030208754 *May 1, 2002Nov 6, 2003G. SridharSystem and method for selective transmission of multimedia based on subscriber behavioral modelUS20040095604 *Mar 31, 2003May 20, 2004Mark MeyerhoferMethod and apparatus for gaming promotional printerUS20040158865 *Nov 21, 2003Aug 12, 2004Kubler Kenneth M.System and method for managing in-theater display advertisementsUS20060039733 *Jun 3, 2005Feb 23, 2006Futurelogic, Inc.Method and apparatus for voucher and coupon printing in a gaming or vending environmentWO2001045004A1Nov 30, 2000Jun 21, 2001Promo VuInteractive promotional information communicating systemWO2004051551A1Nov 28, 2003Jun 17, 2004Haynes SimonFace detection and tracking* Cited by examinerNon-Patent CitationsReference1 *Minority Report Advertising (Mini Cooper style), available at http://curtismorley.com/2007/02/06/minority-report-and-mini-cooper/ (describing the technology used in the movie "Minority Report").* Cited by examinerReferenced byCiting PatentFiling datePublication dateApplicantTitleUS7987111 *Oct 26, 2007Jul 26, 2011Videomining CorporationMethod and system for characterizing physical retail spaces by determining the demographic composition of people in the physical retail spaces utilizing video image analysisUS8218080 *Jun 6, 2006Jul 10, 2012Samsung Electronics Co., Ltd.Personal settings, parental control, and energy saving control of television with digital video cameraUS8244005 *Oct 14, 2010Aug 14, 2012Kabushiki Kaisha ToshibaElectronic apparatus and image display methodUS8351662Sep 16, 2010Jan 8, 2013Seiko Epson CorporationSystem and method for face verification using video sequenceUS8463052 *Sep 14, 2010Jun 11, 2013Kabushiki Kaisha ToshibaElectronic apparatus and image search methodUS8498455Jun 3, 2010Jul 30, 2013Microsoft CorporationScalable face image retrievalUS8510166 *May 11, 2011Aug 13, 2013Google Inc.Gaze tracking systemUS8660307Mar 29, 2012Feb 25, 2014The Nielsen Company (Us), LlcMethods and apparatus to count people in imagesUS8682388Dec 31, 2010Mar 25, 2014Motorola Mobility LlcMobile device and method for proximity detection verificationUS8712110Dec 23, 2009Apr 29, 2014The Invention Science Fund I, LCIdentifying a characteristic of an individual utilizing facial recognition and providing a display for the individualUS8743259 *Dec 30, 2008Jun 3, 2014Nikon CorporationInformation displaying apparatusUS8761442Mar 29, 2012Jun 24, 2014The Nielsen Company (Us), LlcMethods and apparatus to count people in imagesUS20070219866 *Mar 13, 2007Sep 20, 2007Robert WolfPassive Shopper Identification Systems Utilized to Optimize AdvertisingUS20090051542 *Aug 24, 2007Feb 26, 2009Searete Llc, A Limited Liability Corporation Of The State Of DelawareIndividualizing a content presentationUS20110064311 *Sep 14, 2010Mar 17, 2011Kabushiki Kaisha ToshibaElectronic apparatus and image search methodUS20110074540 *Oct 29, 2009Mar 31, 2011Hon Hai Precision Industry Co., Ltd.Control system and method for interface of electronic deviceUS20110110564 *Oct 14, 2010May 12, 2011Kabushiki Kaisha ToshibaElectronic apparatus and image displayUS20110150295 *Dec 23, 2009Jun 23, 2011Searete Llc, A Limited Liability Corporation Of The State Of DelawareIdentifying a characteristic of an individual utilizing facial recognition and providing a display for the individualUS20110150296 *Dec 23, 2009Jun 23, 2011Searete Llc, A Limited Liability Corporation Of The State Of DelawareIdentifying a characteristic of an individual utilizing facial recognition and providing a display for the individualUS20110238361 *Sep 4, 2008Sep 29, 2011Kazuya UekiTallying system, tallying apparatus and tallying methodUS20120239458 *Nov 16, 2009Sep 20, 2012Global Rainmakers, Inc.Measuring Effectiveness of Advertisements and Linking Certain Consumer Activities Including Purchases to Other Activities of the ConsumerUS20120290401 *May 11, 2011Nov 15, 2012Google Inc.Gaze tracking systemUS20130211889 *Feb 9, 2012Aug 15, 2013Ai Cure Technologies Inc.Method and apparatus for encouraging consumption of a product* Cited by examinerClassifications U.S. Classification382/118, 382/103, 705/7.29, 705/14.41International ClassificationG06Q30/00, G06K9/00, G09F27/00, G06T1/00, G06F17/30Cooperative ClassificationG06K9/00295, G06K9/00248, G06K2009/00322, G09F27/00, G06Q30/0201, G06K9/00221, G06Q30/02, G06Q30/0242, G06K9/00771European ClassificationG06Q30/02, G06Q30/0242, G06Q30/0201, G06K9/00F, G06K9/00F3U, G09F27/00, G06K9/00V4, G06K9/00F1LLegal EventsDateCodeEventDescriptionMar 14, 2013FPAYFee paymentYear of fee payment: 4May 2, 2005ASAssignmentOwner name: SONY UNITED KINGDOM LIMITED, UNITED KINGDOMFree format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:KILNER, ANDREW ROGER;JENNINGS, VICTORIA SOPHIA;PASZKOWICZ, SEBASTIAN ALEKSANDER;AND OTHERS;REEL/FRAME:016508/0795;SIGNING DATES FROM 20050102 TO 20050127RotateOriginal ImageGoogle Home - Sitemap - USPTO Bulk Downloads - Privacy Policy - Terms of Service - About Google Patents - Send FeedbackData provided by IFI CLAIMS Patent Services©2012 Google


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Central Ohio Business Recovery Association presents: DR Testing - TechLife Columbus (Columbus, OH)
Central Ohio Business Recovery Association presents: DR Testing
Announcement: the Central Ohio Business Recovery Association has merged with the Ohio Network for Healthcare Information Assurance. We will have three presentations related to best practices for Disaster Recovery testing. Speakers will be Sean Maziarz of The Ohio State University Wexner Medical Center, Matt Honigford of VMware and Reese Foster of Omnicare.
This presentation will be for disaster recovery practitioners in enterprise businesses as well as small businesses.
This event will be held from 9am to 1pm on Thursday September 12 and City BBQ lunch will be provided by Expedient Data Centers. There is no cost to attend, however please register prior to 9/11/13 so proper food and drink will be ordered.
To register for this event or to learn more, please email John Speakman [masked] or Sean Maziarz [masked]
1,519 Columbus Singles

value: This website is a service used to organize online groups that host in-person and virtual events for people with similar interests. It was founded in 2002 by Chairman Scott Heiferman and four co-founders.


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Hot Gay Vampire by Nick Navarre | NOOK Book (eBook) | Barnes & Noble®
When passionate Colin becomes a vampire, his gay desires increase tenfold. He can live by drinking the blood of wildlife. But he’s lonely...and hungry for a different kind of “wildlife.”Adult Content: This book contains sexually graphic scenes depicting adults engaging in sexual acts.This story is approximately 6,500
Hot Gay Vampire available in
When passionate Colin becomes a vampire, his gay desires increase tenfold. He can live by drinking the blood of wildlife. But he’s lonely...and hungry for a different kind of “wildlife.”Adult Content: This book contains sexually graphic scenes depicting adults engaging in sexual acts.This story is approximately 6,500 words--perfect for reading on your iPad, smart phone, or similar device.
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Nick Navarre writes dreamy romance fiction and steamy erotica. He enjoys hiking, camping, mountain biking, working out, snowboarding, reading, and going out with friends. Customer Reviews


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Pole-Vaulter Keeps a Low Profile During Her Ambitious Ascent - The New York Times
More Sports|Pole-Vaulter Keeps a Low Profile During Her Ambitious Ascent
By MICHAEL WEINREB FEB. 2, 2007
Yelena Isinbayeva trained as a gymnast before switching to the pole vault at age 15. Credit Lee Jin-man/Associated Press
Yelena Isinbayeva has heard many things about New York. She has heard that those who visit New York for the first time tend to fall in love with it. But on the ride from the airport to her hotel, she saw nothing of interest, none of the designer shops or gourmet restaurants she would like to visit, and certainly not the Statue of Liberty.
“I think I might have seen it from the plane,” she said.
Perhaps, she said, she will have a couple of hours to play tourist tomorrow morning before a plane takes her back to Italy, where she trains. Or perhaps her visit to New York as a tourist will have to wait until she retires as the greatest women’s pole-vaulter in the young history of the sport. She is only 24, and she is making her first trip to the United States for the 100th Millrose Games tonight at Madison Square Garden.
But as with any elite athlete, there are certain things she must avoid before a competition. Like long walks that might hurt her feet, or drafty rooms and brisk weather that might cause her to catch a cold.
“Of course I would like to see more and more,” she said Wednesday night at her hotel, after she declined an offer to visit Times Square, citing jet lag. “I would like to be all day outside on the street. I’m very interested to see the beautiful places in each town I visit. When I retire, I will go around again.”
It has been a remarkable ascent for Isinbayeva, who came to the pole vault at age 15 after spending her childhood as a gymnast. Her parents enrolled Isinbayeva in gymnastics when she was 5, mainly because they were working full time (her father as a plumber and metalworker, her mother in a boiler room) and needed some way to keep Yelena and her sister busy.
Yelena Isinbayeva of Russia, the world-record holder in the pole vault, is visiting New York for Friday night's Millrose Games. Credit Andrea Mohin/The New York Times
She kept at it for 10 years, even as she grew too tall to harbor any real hopes of becoming an elite gymnast. In the process, she also conquered any fears of putting her body in precarious positions. When her gymnastics coach suggested she try the pole vault, she protested. She had never heard of the pole vault, she said. Her coach told her that if she did not like it, she did not have to continue.
Isinbayeva took to it immediately. And because of her background in gymnastics, she had the type of preparation that few women’s pole-vaulters before her had ever had. She insists she is not particularly fast in her approach, but it is the second phase of her vault, she says, that sets her apart.
In a sport that was added to the Olympics in 2000 (when Stacy Dragila of the United States won the gold medal), Isinbayeva has become the first woman to break the 5-meter mark (a little more than 16-4¾). And she appears determined to continue breaking her own records.
“I saw her in Scotland as a junior at one meet, and I thought she was going to kill herself — she was turning so far upside down it was just scary,” said Dave Nielsen, the track and field coach at Idaho State University, who also coaches Dragila. “She’s a cut above anybody else I’ve seen, certainly.”
In Russia and in Italy, where she now spends much of the year, this success has gained Isinbayeva a certain measure of fame. She did an interview with a Russian radio station in Brooklyn last Sunday, and Millrose organizers are hoping to capitalize on that fame by offering discounts to Russian fans who use a special code word when ordering tickets.
Isinbayeva said that when she got on the plane in Milan, on her way to New York, the security officer who checked her boarding pass recognized her immediately.
“After the Olympics was the boom,” she said. “At first, it was strange. I said, ‘How do they know me?’ ”
In the United States, however, where virtually no one knows her, where she will spend nearly all of her time in Madison Square Garden or in a hotel directly across the street, she will keep her low profile. At least for now.
A version of this article appears in print on , on Page D6 of the New York edition with the headline: Pole-Vaulter Keeps a Low Profile During Her Ambitious Ascent. Order Reprints| Today's Paper|Subscribe

value: This website is an American daily newspaper based in New York City with a worldwide readership. Founded in 1851, the Times has since won 132 Pulitzer Prizes, the most of any newspaper, and has long been regarded within the industry as a national "newspaper of record".


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artifactory - Is it possible to set a socket timeout for ad-hoc replications? - Stack Overflow
Is it possible to set a socket timeout for ad-hoc replications?
We're triggering replication of a local repository between 2 Artifactory instances using the REST API at /api/replication/execute (https://www.jfrog.com/confluence/display/RTF/Artifactory+REST+API#ArtifactoryRESTAPI-Pull/PushReplication). There's a considerable distance between the servers; the source is in Europe and the destination in Australia.
On the source server we see exceptions like:
2018-11-08 19:22:39,242 [art-exec-23] [ERROR] (o.a.a.c.BasicStatusHolder:214) - Error occurred while performing folder replication for 'somerepo-local:': Read timed out
at org.jfrog.client.http.CloseableHttpClientDecorator.doExecute(CloseableHttpClientDecorator.java:104)
at org.artifactory.addon.replication.core.context.RemoteRequestExecutor.executeMethod(RemoteRequestExecutor.java:32)
at org.artifactory.addon.replication.core.BaseReplicationProducer.fullTree(BaseReplicationProducer.java:155)
at org.artifactory.addon.replication.core.BaseReplicationProducer.produce(BaseReplicationProducer.java:146)
at org.artifactory.addon.replication.core.BaseReplicationProducer.run(BaseReplicationProducer.java:71)
at org.artifactory.addon.replication.core.push.full.PushReplicationProducer.execute(PushReplicationProducer.java:81)
at org.artifactory.addon.replication.core.push.full.FullReplicationStrategySelector$FullReplication.execute(FullReplicationStrategySelector.java:156)
at org.artifactory.addon.replication.core.push.full.PushReplicator.replicate(PushReplicator.java:52)
at org.artifactory.addon.replication.core.push.full.PushReplicator.replicate(PushReplicator.java:26)
at org.artifactory.addon.replication.core.ReplicationAddonImpl.performLocalReplication(ReplicationAddonImpl.java:102)
at org.artifactory.repo.replication.PushReplicationJob.handleReplication(PushReplicationJob.java:154)
at org.artifactory.repo.replication.PushReplicationJob.onExecute(PushReplicationJob.java:81)
at org.artifactory.schedule.quartz.QuartzCommand.execute(QuartzCommand.java:48)
I'm aware that its possible to configure a socket timeout when the replication is configured from the UI. But does anyone know if its possible to set a timeout for 'ad-hoc' replications triggered this way?
Note that its not an option for us to configure replications from the UI because we need to replicate to more than one destination and our license doesn't support 'multi-push'
asked Nov 8 at 23:20
Is it possible to rename repositories in Artifactory?
Atrifactory Pro's feature: Repository Replication
Artifactory replication after connection reset
Artifactory replication protocol
Push replication on pypi repos
Which servers require an enterprise license for event-based pull replication?
JFrog Artifactory - Searching virtual repository possible?

value: This website is a question and answer website for professional and enthusiast programmers. It is the flagship site of the Stack Exchange Network, created in 2008 by Jeff Atwood and Joel Spolsky.


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Cooker Thermocouple | eBay
Cooker Thermocouples
Universal Oven Cooker Gas Thermocouple Kit 60cm 600mm. Fits a variety of gas appliances such as ovens, cookers & boilers. Unit 5B, Drum Industrial Estate. We promote a 'repair not replace' culture ins...
Time left: 12d 10h 5m
User ID lmelectrical (Feedback score 1566986)
Universal Oven Cooker Gas Thermocouple Kit 60cm 600mm. Fits a variety of gas appliances such as ovens, cookers & boilers.
Genuine Original Belling Oven Cooker Thermocouple (1300mm). Length: 1300mm.
Universal Cooker Main Oven Thermocouple 1450mm For Beko, Belling, Flavel, Stoves
Compatible 1450mm thermocouple for Beko, Belling, Flavel, Stoves, Leisure, New World ovens. Length of thermocouple – 1450mm. We promote a 'repair not replace' culture instead of a 'throwaway society'.
UNIVERSAL GAS OVEN COOKER THERMOCOUPLE 1200MM LONG 48 INCH
This thermocouple is 1200mm long, so providing your appliance is compatible, it should fit perfectly in to your cooker. UNIVERSAL, ANY THAT TAKES AS 1200MM THERMOCOUPLE. This oven thermocouple is a ge...
Genuine Original New World Oven Cooker Thermocouple (1300mm). Length: 1300mm. NEW WORLD. This will enable us to assist you more thoroughly with your request and to deal with any difficulties.
BELLING STOVES NEW WORLD GRILL COOKER THERMOCOUPLE 081528402 GENUINE PART
GENUINE BELLING STOVES NEW WORLD GRILL COOKER THERMOCOUPLE 081528402. Manufacturer's Code - 081528402. GENUINE BELLING STOVES NEW WORLD GRILL COOKER THERMOCOUPLE. This thermocouple is a genuine spare ...
RANGEMASTER Genuine Hotplate Thermocouple Probe for Oven Cooker Hob 7489
Genuine RANGEMASTER Oven Hotplate Thermocouple Probe. Fits models.
Thermocouple- R/H for Homark Cooker Equivalent to 081366700
Genuine spare part for select Belling, New World and Stoves cookers. Faulty products will replaced upon receipt of the faulty item unless authorized by us.
BELLING STOVES NEW WORLD OVEN COOKER 1300MM THERMOCOUPLE 081366700 GENUINE PART
GENUINE BELLING STOVES NEW WORLD OVEN COOKER 1300MM THERMOCOUPLE 081366700. Manufacturer's Code - 081366700. GENUINE BELLING STOVES NEW WORLD OVEN COOKER 1300MM THERMOCOUPLE. This oven thermocouple is...
100G, 100GANT, 757, 758, 923 AN, 923CH, 923GR, 923SI, G755AN, G755MK2AN, G755MK2WH, G755WH, G756AN, G756WH. Compatible 1450mm thermocouple for your Belling main oven. Length of thermocouple – 1450mm. ...
Cannon Creda Hotpoint Indesit Cooker Grill Thermocouple. Genuine Part Number C00
Cannon Creda Hotpoint Indesit Cooker Grill Thermocouple. Genuine Part Number C00. Genuine spare part for select models of Cannon, Hotpoint and Indesit grills. Faulty products will replaced upon receip...
Beko JMB Cooker Thermocouple. Genuine Part Number 230311005. Genuine spare part for select Beko cookers. Faulty products will replaced upon receipt of the faulty item unless authorized by us.
Thermocouple for Smeg Cooker Equivalent to 948650101
Genuine Cannon Cooker Oven Thermocouple 1400mm
GAS THERMOCOUPLE TESTER PUSH BUTTON TESTING TOOL FOR COOKERS FIRES HOBS BOILERS
GAS THERMOCOUPLE QUICK TESTING TOOL. CPUK Part Number: TC TESTER. Tester Plasticised Body Height: 25mm. Tester Nut Height: 10mm.
Thermocouple: Cannon Hotpoint Cannon Hotpoint Indesit 1400mm cooker thermocoup
Genuine Indesit spare part for select Cannon, Hotpoint and Indesit models. Faulty products will replaced upon receipt of the faulty item unless authorized by us.
UNIVERSAL Thermocouple Kit 1500mm & Fixings Gas Boiler Oven Cooker Grill
UNIVERSAL 1500MM THERMOCOUPLE KIT. BOILERS, OVENS, FAT FRYERS, BAIN MARIES, PIE CABINETS,KEBAB MACHINES.
Genuine Smeg Oven Cooker 650mm Thermocouple 948650091
SMEG Oven Cooker Thermocouple 650mm 650 mm 948650117 Replacement Spare
Length: 650mm. This will enable us to assist you more thoroughly with your request and to deal with any difficulties.
BEKO BELLING FLAVEL OVEN COOKER THERMOCOUPLE 1450MM 430920001 230100020 GENUINE
GENUINE BEKO BELLING FLAVEL OVEN COOKER THERMOCOUPLE 1450MM 430920001 230100020. Manufacturer's Part Number Code - 430920001 230100020. GENUINE BEKO BELLING FLAVEL OVEN COOKER THERMOCOUPLE 1450MM. Thi...
SMEG Oven Cooker Thermocouple 650mm 650 mm 948650127 Replacement Spare
SMEG Oven Cooker Thermocouple 450mm 450 mm 948650101 Replacement Spare
Length: 450mm. This will enable us to assist you more thoroughly with your request and to deal with any difficulties.
Genuine Indesit KD6G25A KD6G25SXIR KD6G25X(T) Cooker Oven Thermocouple 1400mm
KD6G25A, KD6G25SXIR, KD6G25X(T). This Is A Genuine Part.
Genuine SMEG Oven Cooker 500mm Base Hob THERMOCOUPLE 948650104
STOVES Oven Cooker Hob Thermocouple 1300mm 1300 mm Genuine
Genuine Original Stoves Oven Cooker Thermocouple (1300mm). Length: 1300mm.
BELLING NEW WORLD LEISURE Genuine Oven Cooker 1450mm Thermocouple
CM101NRC, CM101NRCP, CM101NRK, CM101NRKP, CM10NRC, CM10NRK, DVGGL26C, DVGGL26G, DVGGL26LC, DVGGL26LG, DVGGL36BK, DVGGL36LBK, EST5LSI, EST5LW, LEISURE, ST5LESB, ST5LEWB.
SMEG Oven Cooker Thermocouple 600mm 600 mm 948650108 Replacement Spare
Length: 600mm. This will enable us to assist you more thoroughly with your request and to deal with any difficulties.
Genuine Indesit Oven Cooker Grill Thermocouple
Zanussi Oven Cooker Grill Thermocouple Genuine Spare Part
ZANUSSI Oven Grill Thermocouple. This will enable us to assist you more thoroughly with your request and to deal with any difficulties.


text:
25 Washington St, Wellesley, MA 02481 25 Washington St, Wellesley Directions
+17812637234
Wellesley's CVS Pharmacy offers an assortment of drugstore goodies, including toiletries, medicine, beauty products and skincare products.
At CVS Pharmacy, drivers will appreciate the ample parking options in the area. So be sure to swing by CVS Pharmacy in Wellesley, your friendly neighborhood drugstore, for all those last minute purchases.

value: This website is an American global e-commerce marketplace connecting subscribers with local merchants by offering activities, travel, goods and services in 15 countries. Based in Chicago, Groupon was launched there in November 2008, launching soon after in Boston, New York City and Toronto.


text:
Get a BEER* and Undo Nonprofit Power Dynamics Day Happy Hour - DC Tickets, Thu, Jun 21, 2018 at 4:30 PM | Eventbrite
Thu, June 21, 2018, 4:30 PM – 6:30 PM EDT
We’ll be gifting a copy of Vu, Jane and Jessamyn’s book, The Unicorns : A Nonprofit Relationship Guide Book, to the first 10 pairs (nonprofit and grantmaker) who sign up for our happy hour, so start reaching out to your grantees to see who’s available to join you on June 21.
Get a BEER* and Undo Nonprofit Power Dynamics Day Happy Hour - DC at Tonic At Quigley's
2036 G Street Northwest, Washington, DC 20036
MANNA Happy Hour at Madam's Organ
Jess King for Congress PA 11 @ Colony Club DC, June 26, 5:30 - 8 pm
SI360 Professionals Program
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Patent US5317924 - Self-retaining, self-sealing pressure sensor - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign inAdvanced Patent SearchPatentsA self-retaining, self-sealing manifold pressure sensor includes a sensor body with depending stem and an enlarged lower foot on the stem. The stem is tightly surrounded by a sealing and retention boot, which has a lower flange located just above the stem foot, which is larger than the stem foot. The...http://www.google.com/patents/US5317924?utm_source=gb-gplus-sharePatent US5317924 - Self-retaining, self-sealing pressure sensorAdvanced Patent SearchPublication numberUS5317924 APublication typeGrantApplication numberUS 07/912,379Publication dateJun 7, 1994Filing dateJul 13, 1992Priority dateJul 13, 1992Fee statusPaidAlso published asDE69310447D1, DE69310447T2, EP0579308A1, EP0579308B1Publication number07912379, 912379, US 5317924 A, US 5317924A, US-A-5317924, US5317924 A, US5317924AInventorsSteven R. MaackOriginal AssigneeDelco Electronics CorporationExport CitationBiBTeX, EndNote, RefManPatent Citations (13), Referenced by (13), Classifications (7), Legal Events (4) External Links: USPTO, USPTO Assignment, EspacenetSelf-retaining, self-sealing pressure sensor
US 5317924 AAbstract
1. A self-retaining, self-sealing pressure sensor assembly for installation through a fixed diameter installation hole in a wall that separates an enclosed pressure from ambient pressure and which is subject to significant, rapid fluctuations above ambient pressure that tend to expel said sensor assembly, comprising:a sensor body including a depending stem having an enlarged lower foot that is smaller in size that the diameter of said installation hole, and a retention and sealing boot of resilient, flexible sealing material surrounding said sensor body stem having a sealing surface with a diameter substantially equal to said installation hole, and an enlarged lower flange with a diameter larger than said installation hole, whereby, said sensor body and sealing boot may be installed by simultaneous insertion through said installation hole as said enlarged lower flange flexes to pass through said installation hole, after which said stem and installation hole are both sealed against pressure loss by sealing engagement with said boot, and said sensor body is retained against expulsion by said enlarged lower flange being trapped between said sensor body enlarged foot and an interior surface of said wall which is subject to said enclosed pressure. 2. A self-retaining, self-sealing pressure sensor assembly for installation through a fixed diameter installation hole in a wall that separates an enclosed pressure from ambient pressure and which is subject to significant, rapid fluctuations above ambient pressure that tend to expel said sensor assembly, comprising:a sensor body including a depending stem having a generally cylindrical outer surface and an enlarged lower foot that is smaller in size than the diameter of said installation hole, and a retention and sealing boot of resilient, flexible sealing material including a generally cylindrical central passage with a diameter substantially equal to said stem outer surface, a sealing surface with a diameter substantially equal to said installation hole, and an enlarged lower flange with a diameter larger than said installation hole, whereby, said sealing boot may be first installed to said sensor body by inserting said stem and enlarged lower foot through said central passage, which expands and retracts into tight fitting sealing engagement around said stem as said enlarged foot passes through, after which said sensor body and boot may be installed by simultaneous insertion through said installation hole as said enlarged lower flange flexes to pass through said installation hole, after which said stem and installation hole are both sealed against pressure loss by sealing engagement with said boot, and said sensor body is retained against expulsion by said enlarged lower flange being trapped between said sensor body enlarged foot and an interior surface of said wall which is subject to said enclosed pressure. Description
Patent CitationsCited PatentFiling datePublication dateApplicantTitleUS2546672 *Jul 10, 1948Mar 27, 1951Tecalemit LtdNipple or lubricant-receiving deviceUS3012699 *Sep 5, 1958Dec 12, 1961Rubber Seal Products Co IncDispensing device for relatively thick liquidsUS3438397 *Oct 20, 1965Apr 15, 1969Universal Controls CorpPressure test plug and means for bypassing gas metersUS3580988 *Aug 12, 1969May 25, 1971AmpexGrommet for speaker enclosureUS3621952 *Nov 5, 1969Nov 23, 1971Gen Motors CorpSpring loaded piston rod sealUS4180297 *Sep 22, 1977Dec 25, 1979General Electric CompanySealing grommet in a refrigerator cabinetUS4274545 *Jun 14, 1979Jun 23, 1981Lafrance CorporationInstrument housingUS4682707 *Feb 14, 1986Jul 28, 1987National Can CorporationContainer having a tamper proof lidUS4683757 *Mar 24, 1986Aug 4, 1987Motorola, Inc.Axial pressure sensorUS4693112 *Jun 12, 1986Sep 15, 1987Ferris James EAir conditioner refrigerant check gauge insert convertible to a tire check gaugeUS4942383 *Mar 6, 1989Jul 17, 1990Honeywell Inc.Low cost wet-to-wet pressure sensor packageUS5029879 *Feb 28, 1990Jul 9, 1991Injection Plastics Manufacturing Company, Inc.Seal for pipe to wall junctionsGB2123904A * Title not available* Cited by examinerReferenced byCiting PatentFiling datePublication dateApplicantTitleUS5438877 *Jun 13, 1994Aug 8, 1995Motorola, Inc.Pressure sensor package for reducing stress-induced measurement errorUS5834652 *Nov 24, 1997Nov 10, 1998Mitsubishi Denki Kabushiki KaishaPressure sensing device with elastic sealing member and method of easy installationUS5945606 *Aug 29, 1997Aug 31, 1999Desno CorporationElastic member, and method and structure for attaching sensor to sensor attachment member using the sameUS6539786May 11, 2000Apr 1, 2003Siemens Canada LimitedSensor attachment arrangement having extending membersUS6779406Feb 4, 2003Aug 24, 2004Delphi Technologies, Inc.Self-retaining pressure sensor assembly having notched seal retention flangeUS7082869Jun 2, 2003Aug 1, 2006Lucas Automotive GmbhSensor arrangement for a vacuum brake booster and a vacuum brake booster provided with this sensor arrangementUS7114632 *May 2, 2002Oct 3, 2006Trw Automotive Electronics & Components Gmbh & Co. KgSealing coverUS7574921Feb 5, 2007Aug 18, 2009Robert Bosch GmbhPressure sensor mounting using a molded sealUS7608011 *Dec 10, 2003Oct 27, 2009Ford Global Technologies, LlcHydrogen fuelled hybrid powertrain and vehicleUS7636053Sep 20, 2006Dec 22, 2009Toyota Motor Engineering & Manufacturing North America, Inc.Article and method for monitoring temperature and pressure within a pressurized gas cylinderUS20100308192 *Jan 31, 2008Dec 9, 2010Zf Friedrichshafen AgSensor attachment arrangementDE10058058A1 *Nov 23, 2000May 23, 2002Siemens AgPressure sensor for use in the inlet to a combustion engine, with housing and O-ring arrangement for easy mounting in its measurement positionDE10061152A1 *Dec 8, 2000Jun 27, 2002Lucas Varity GmbhSensoranordnung f�r einen Unterdruck-Bremskraftverst�rker und damit ausger�steter Unterdruck-Bremskraftverst�rker* Cited by examinerClassifications U.S. Classification73/756, 220/691International ClassificationG01L19/00, G01D11/30, G12B9/08Cooperative ClassificationG01L19/0007European ClassificationG01L19/00BLegal EventsDateCodeEventDescriptionDec 5, 2005FPAYFee paymentYear of fee payment: 12Nov 30, 2001FPAYFee paymentYear of fee payment: 8Dec 1, 1997FPAYFee paymentYear of fee payment: 4Jul 13, 1992ASAssignmentOwner name: DELCO ELECTRONICS CORPORATION A CORP. OF DELAWAFree format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:MAACK, STEVEN R.;REEL/FRAME:006191/0778Effective date: 19920624RotateOriginal ImageGoogle Home - Sitemap - USPTO Bulk Downloads - Privacy Policy - Terms of Service - About Google Patents - Send FeedbackData provided by IFI CLAIMS Patent Services


text:
by Melissa Kotkin
New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution
Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline A. French, MD New Concepts, Old Dilemmas: Drugs on the Horizon and Generic Substitution Jacqueline French, MD
New Horizons and Old Dilemmas: New AEDs and Generics Jacqueline A. French, M.D. NYU Comprehensive Epilepsy Center 2.
ANTIEPILEPTIC DRUG DEVELOPMENT 1840 1860 1880 1900 1920 1940 1960 1980 2000 0 5 10 15 20 Bromide Phenobarbital Phenytoin Primidone Ethosuximide Sodium Valproate Benzodiazepines Carbamazepine Zonisamide Felbamate Gabapentin Topiramate Fosphenytoin Oxcarbazepine Tiagabine Levetiracetam Rufinamide Lacosamide Pregabalin Retigabine Brivaracetam Eslicarbazepine Clobazam ? Calendar Year Number of Licensed Antiepileptic Drugs Lamotrigine Vigabatrin 3.
SINCE 1998 2000 0 5 10 20 Zonisamide Felbamate Gabapentin Topiramate Fosphenytoin Oxcarbazepine Tiagabine Levetiracetam Pregabalin Calendar Year Number of Licensed Antiepileptic Drugs Lamotrigine 1990 Rufinamide Lacosamide 2010 Vigabatrin 4.
DO WE NEED MORE NEW ANTIEPILEPTIC DRUGS?

Problem with current AEDs:

Seizure control

Newly diagnosed well treated

Still 40% with therapy resistance

New AEDs over last 20 years have not changed this equation!

Safety/tolerability

Some new (and old) AEDs still have important safety and tolerability problems

How do we make progress?

Revolutionary Drugs

Drugs that work with new mechanisms never tried before

Expectation: They will control seizures that existing drugs can ’ t control

Evolutionary Drugs

Improve on existing drugs

Expectation: We can eliminate some of the problems/side effects of good drugs, without reducing their effect on seizures

Compounds which are second or third generation derivatives of AEDs introduced before 1970 1 st Generation AED CarbamazepineeTegretol TM Valproic Acid Depakote TM 2 nd Generation AED Oxcarbazepine Valrocemide (SPD–493) Valnoctamide 3 rd Generation AED Eslicarbazepine Acetate (BIA 2-093) Phenobarbital T2000 Perucca et al, Lancet Neurol , 2007 7.
Compounds which are second generation derivatives of AEDs introduced after 1990 Gabapentin Levetiracetam Pregabalin Brivaracetam (ucb 34714) Precursor CNS Drug Piracetam 1 st Generation AED 2 nd Generation AED Perucca et al, Lancet Neurol , 2007 8.
What ’s “ new ” this year?

One “Old” drug finally coming to US

Frisium (clobazam)

Benzodiazepine which is for chronic use

Has been available in Europe and Canada for decades

Studies for Lennox-Gastaut, soon to be submitted to FDA

One new drug to be approved

Revolutionary

Potiga (Retigabine)

Three drugs in late trials

Evolutionary

Rikelta (brivaracetam)

Stedesa (eslicarbazepine)

Revolutionary:

Perampanel

Retigabine

Works on a NEW channel that other drugs don ’ t work on (Potassium channel)

Defect in potassium channel linked to one inherited form of epilepsy (benign neonatal seizures)

Will be approved for add-on treatment in partial seizures only

Was reviewed at an FDA advisory panel, received “approval” by panel, awaiting resolution of manufacturing issues for full approval

Patients with > 50% Seizure Reduction in Overall Treatment Period (Titration + Maintenance) Study 302 Study 301 *p<0.005 **p<0.001 % Patients 179 181 178 152 153 Placebo 600 900 Placebo 1200 RTG RTG 11.
Retigabine 1200 mg/day vs Placebo: Most Common Adverse Events ( > 10% incidence) % Patients Placebo (N=152) RTG (N=153) Dizziness 14 40 Somnolence 17 31 Fatigue 8 16 Confusion 2 14 Dysarthria 2 12 Headache 18 12 Ataxia 4 12 Urinary tract infection 9 12 Tremor 4 11 Vision blurred 3 11 Nausea 7 10 12.
Discontinuations Due to Adverse Events *Dose-related

Adverse event as primary reason for discontinuation

RTG

Placebo (N=331)

600 (N=181) 900 (N=178) 1200 (N=153)

8%

14% 26% 27%

Cause for discontinuation in >3% of patients

Dizziness*

Confusion*

Somnolence

Fatigue

Rare bladder issues will require monitoring

Perampanel

First AED to work on excitation rather than inhibition or stabilization of membranes

Inhibits excitatory chemical in the brain (AMPA)

Will be approved for add-on treatment in partial seizures first

Will be submitted to FDA this year

Perampanel : Percent change in seizure frequency during maintenance phase Median % change in seizure frequency -40 -30 -20 -10 0 -50 Placebo (n=119) Perampanel 8 mg/day (n=132) Perampanel 12 mg/day (n=130) -22.86 -32.13 ( P =0.08) -39.48 ( P =0.03) 15.
Treatment-emergent side effects (add-on) TEAEs, treatment-emergent adverse events Placebo Perampanel Treatment emergent Side effects % N (n=121) 8 mg (n=133) 12 mg (n=134) TEAEs leading to study or study drug withdrawal 43 6.6 6.8 19.4 Most common (≥10%) Dizziness 113 9.9 37.6 38.1 Sleepiness 63 13.2 18.0 17.2 Irritability 35 5.0 7.5 14.2 Headache 54 13.2 15.0 13.4 Fall 38 6.6 9.8 12.7 Ataxia 24 0 6.0 11.9 16.
OLD MECHANISM-MORE POWERFUL/SAFER Brivaracetam (Rikelta) Eslicarbazepine Acetate (Stedesa) 17.
BRIVARACETAM (Rikelta)

Similar mechanism to Levetiracetam (Keppra TM ) but much stronger in animal models

Also has sodium channel blocking activity

Keppra causes irritability/depression in some patients-unknown if Rikelta will have improved tolerability profile

FDA trials underway. First study very positive, second study unclear, third trial underway

First approval will be for add-on therapy for partial seizures. Other uses (eg for generalized seizures) will be explored later

Efficacy of Brivaracetam (5, 20 and 50 mg/day) Add-on Treatment in Refractory Partial-Onset Epilepsy

SEIZURE-FREEDOM RATES

RESPONDER RATES ITT population: n=208; 110M, 98F; age range 16–65 y PBO (n=54) BRV5 (n=50) BRV20 (n=52) BRV50 (n=52) 0 10 20 30 40 50 60 16.7% p = 0.047 32.0% p = 0.002 44.2% p = 0.001 55.8% % Respondents PBO (n=54) BRV5 (n=50) BRV20 (n=52) BRV50 (n=52) 0 10 % Patients 1.9% 1/54 8.0% 4/50 7.7% 4/52 7.7% 4/52 19.
Brivaracetam Adverse Events PBO BRV5 BRV20 BRV50 Patients (N) 54 50 52 52 Permanent study drug discontinuation 2 (3.7) 3 (6.0) 1 (1.9) 0 Patients with ≥1 AE, n (%) 29 (53.7) 26 (52.0) 29 (55.8) 28 (53.8) Total AEs 59 50 72 56 AEs reported in ≥ 5% patients Headache Somnolence Influenza Dizziness Neutropenia Fatigue 4 (7.4) 4 (7.4) 4 (7.4) 3 (5.6) 1 (1.9) 2 (3.7) 4 (8.0) 1 (2.0) 4 (8.0) 1 (2.0) 4 (8.0) 0 2 (3.8) 3 (5.8) 0 0 2 (3.8) 2 (3.8) 1 (1.9) 3 (5.8) 1 (1.9) 4 (7.7) 0 3 (5.8) 20.
Problems with Carbamazepine

Effective drug but…

Speeds metabolism through the liver, causing:

Need for dose adjustment of other drugs that are taken simultaneously

Changes (reduction) in levels of vitamins, hormones

Increase in cholesterol levels, lipid levels

Reduction in sodium (salt) levels in the blood that can lead to problems

Change in Cholesterol after removal of Tegretol or Dilantin (First to second blood draw) Mintzer S. et al Effects of antiepileptic drugs on lipids, homocysteine, and C-reactive protein. Ann Neurol. 2009 Apr;65(4):448-56. Tegretol Dilantin CONTROL 22.
Eslicarbazepine

A “third generation” Carbamazepine (Tegretol TM )

Improves on second generation (Trileptal TM )

Less effect on sodium

Smoother release may produce less side effects

Does not have the same impact on the liver

Hopefully will work equally as well

Already approved in Europe as “ Zebenix ” . Will be submitted to FDA for approval as add-on therapy of partial seizures

Results from 3 Eslicarbazepine Pivotal Trials: 50% Responder Rates Study BIA-2093-301 Study BIA-2093-302 Study BIA-2093-303 Response Rate (%) 50 45 40 35 30 25 20 15 10 5 0 McCormack PL, et al. CNS Drugs . 2009. 23(1):71-9. 800 mg and 1200 mg doses were statistically significant; 400 mg was not. PL ESL 400 mg od ESL 800 mg od ESL 1200 mg od 24.
Integrated Analysis of 3 Phase III Studies : Safety Results

Most common Side effects: dizziness, sleepiness, headache, nausea, vomiting, double vision, abnormal coordination

Low incidence of hyponatremia

Not associated with changes in total cholesterol, low density lipoprotein (LDL) levels, and glucose

No systematic effect on body weight

The Epilepsy Study Consortium

Sponsored by Epilepsy Therapy

Development Project and FACES

Group of Epilepsy Centers who

work together to write protocols, bring better drugs forward,

Maintain the focus of drug development on helping people with epilepsy, NOT comercial concerns of pharmaceutical companies!

The future

Need active pipeline with good compounds moving through

Need better trial designs

Shorten placebo period?

Weed out effective drugs from non-effective

Improve risk-benefit

Acceptance by FDA of 2 new trial designs will speed good therapies

Many Drugs going off Patent

This allows multiple (generic) companies to make the drug, in addition to the brand manufacturer

At same dose, two formulations must be within 80%-125% of amount in brand, with 90% assurance.

Different generic brands could be either high or low

If a physician does not check the “do not substitute” box, insurance companies are at liberty to switch patients to generic

Generics

Drugs off patent (available in generic)

Dilantin (phenytoin)

Tegretol (carbamazepine)

Neurontin (gabapentin)

Lamictal (lamotrigine)

Topamax (topiramate)

Trileptal (oxcarbazepine)

Keppra (levetiracetam)

Zonisamide (Zonegran)

Source: WKH PHAST TRX and Sales data factored by Verispan PDDA Note: Celexa included as a reference of typical generic erosion Prescription Generic Erosion Brand TRx as Percent of Total Molecule 30.

Generics may be very good and close to the brand; The problem is that EACH TIME a new prescription is filled, it can be filled with a different company ’s generic, which could be high or low.

Different generics can also look different than the brand, causing confusion Tegretol Carbamazepine (Generic) 32.
Cost

Most insurance companies charge some additional cost for branded drugs

Some companies will only pay for generics if they are available

The cost differential for some patients may be hundreds of dollars a month, making brand name simply unaffordable

Generic Carbamazepine Products May Show Large Variations

Five generic carbamazepine formulation-FDA-approval packets were assessed, data obtained using the Freedom of Information Act

Looked at two properties: Overall exposure (AUC) and maximum blood concentration (Cmax)

The AUC & Cmax of three generics were accurate copies of Tegretol®

For two generics, the mean AUC & C max values were near the acceptance range of Tegretol ®

Model of switches between two generic CBZ formulations produced AUC variations up to 21% & Cmax variations up to 40%

Chuang et al., 34.

No well performed studies to assess risk from switching between generics

Excipients and colorants may be different, leading to potential for allergic reactions

Dissolution properties may vary

Drug Must Be in Solution to be Absorbed Drug in Blood Dissolution of Drug Drug in Solution Result Desired pharmacological effect achieved (seizure reduction) Solid Dosage Form 36.
Active Drug Substances (continued)

Seven Possible Components of a Tablet

Active Drug Substance (ADS)

Binders

Fillers

Disintegrants

Lubricants

Colors

Flavors

NOTE: The possible tablet components are rarely The same for the Brand and its Generic counterpart. 37.
Bioavailability

Physical characteristics of drug and composition of the tablet can effect the . . .

Disintegration

Dissolution

This can effect the way the drug acts in the body

Understanding Components Active Drug Substances

Properties/Attributes of Active Drug Substances (ADS)

Polymorphic Crystal Form

The Salt Form

The Particle Size

Hydrated vs. Anhydrous Form

Wettability

Solubility

Impurity Profile

Sources may be different resulting in differences that

May or may not be important.

What Data Suggest Problems with Switching?

Physician surveys

Switchback data (Canada)

More patients with epilepsy switch back to brand after using generic

Increase usage of Emergency services and overall health care after switch from brand to generic

Generic savings partially offset by increased dose and increased use of other AED and non-AED after switch

Are these sources reliable?

All these sources are subject to bias

Patients are anxious after switch and may be more aware of problems

Remember emergent side effects on placebo)

Position Statement Epilepsy Foundation of America Foundation Opposes Mandatory Substitution for Antiepileptic Drugs The Epilepsy Foundation has had a historical position opposing mandatory substitution of generic drugs for brand name since generics first became available because of concerns about reported breakthrough seizures in some people with epilepsy when they are switched from one version of a medication to another. Other medical organizations focused on the treatment of epilepsy have had similar positions. 42.
Position Statement American Academy of Neurology (AAN) The AAN, representing over 19,000 neurologists and neuroscience professionals, has taken an active interest in the clinical, ethical and policy considerations concerning the coverage of anticonvulsant drugs for people with epilepsy. The AAN opposes generic substitution of anticonvulsant drugs for the treatment of epilepsy without the attending physician ’ s approval. The FDA has allowed for significant differences between name-brand and generic drugs. This variation can be highly problematic for patients with epilepsy. Even minor differences in the composition of generic and name-brand anticonvulsant drugs for the treatment of epilepsy can result in breakthrough seizures. 43.
Bottom Line

Generic Substitution has not been shown definitively to cause a problem

More studies needed

Switching probably safe for most people

May be a financial necessity for many

Who Should Be More Concerned?

People whose seizures were controlled only after careful adjustment of one or more AEDs

The elderly

Patients taking multiple AEDs, who are at risk for drug interactions

Changing to Generic (or to Brand): Best practices

Physician should get baseline drug levels

Check level again when stable on new preparation

Ideally limit changes between different generic manufacturers

Report suspected problems (preferably with documentation) to FDA MedWatch (http://www.fda.gov/medwatch/)!

Melissa Kotkin

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