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The Budos Band II by The Budos Band (Vinyl, Oct-2007, Daptone) | eBay
The Budos Band II by The Budos Band (Vinyl, Oct-2007, Daptone)
With his tail arched high in readiness, he maneuvers patiently under the scorching desert sun and chooses his prey. He strikes without warning and without remorse. While their debut album was itself heralded as a groundbreaking exploration of funk, Afro-beat and Soul music, few could predict that their second effort would not only match but surpass the realm of mind-expansion embodied on their first sessions.
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item 1 The Budos Band - Budos Band II [New Vinyl] -The Budos Band - Budos Band II [New Vinyl]
item 2 Budos Band, The-The Budos Band Ii (US IMPORT) VINYL LP NEW -Budos Band, The-The Budos Band Ii (US IMPORT) VINYL LP NEW
item 3 Budos Band, The-The Budos Band Ii VINYL LP NEW -Budos Band, The-The Budos Band Ii VINYL LP NEW
item 4 The Budos Band - II Vinyl LP Daptone Re NEW -The Budos Band - II Vinyl LP Daptone Re NEW
item 5 New Budos Band Ii - Budos Band - Vinyl -New Budos Band Ii - Budos Band - Vinyl
item 6 New Budos Band Ii - Budos Band - Rock & Pop Music Vinyl -New Budos Band Ii - Budos Band - Rock & Pop Music Vinyl
item 7 BUDOS BAND - BUDOS BAND II NEW VINYL -BUDOS BAND - BUDOS BAND II NEW VINYL
James Brown's Funky People, Pt. 2 by James Brown (R&B) (Vinyl, Jan-2017, Get On Down)
Superfunk by Funk, Inc. (Vinyl, BGP (Beat Goes Public))
Afreaka! by Demon Fuzz (Vinyl, Sep-2017, Music on Vinyl)
Hits, Rarities & Remixes by A Tribe Called Quest (Vinyl, Jun-2003, 2 Discs, Jive (USA))
Greek Theater, Berkeley 1984 by Augustus Pablo (Vinyl, Jun-2014, Cleopatra)
By All Means Necessary by Boogie Down Productions (Vinyl, Aug-2015)
Ghetto Music: The Blueprint of Hip Hop by Boogie Down Productions (Vinyl, May-2017, Get On Down)
Rejuvenation [Bonus Tracks] by The Meters (Vinyl, Dec-2013, Music on Vinyl)
The Band LP Vinyl Records 2007
The Band Music CDs in English 2007


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BBC News - Petrol bombs thrown at Willowfield PSNI station in Belfast
Petrol bombs thrown at Willowfield PSNI station in Belfast
Two petrol bombs hit the police station on Sunday night
Two petrol bombs have been thrown at Willowfield police station in east Belfast.
The devices were thrown at the station from the direction of Willowfield Drive at about 23:40 BST on Sunday night.
No damage was caused. Police have appealed for witnesses to the attack to contact them.
DUP assembly member Robin Newton said there was no justification for the attack, which he described as "mindless".
"Anyone who is prepared to put life at risk by throwing petrol bombs is a danger to the whole community and needs to be taken before the courts," he said. East Belfast MP Naomi Long also condemned the attack.
"Those responsible are just interested in mindless violence and do not have any regards for the consequences of their actions," she said. Share this page

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Cheap flights from London to San Sebastian de la Gomera - TripAdvisor - [LON - GMZ]
Cheap flights from London (LON) to San Sebastian de la Gomera (GMZ) Review
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Patent US4901708 - Viewing laryngoscope - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign inAdvanced Patent SearchPatentsA laryngoscope curved blade includes a pair of fiber optic bundles, one fiber optic bundle adapted to transmit light to the distal end of the blade and the other fiber optic bundle adapted to provide a viewing channel for telescopic viewing of the area adjacent to the distal end of the blade. A lens...http://www.google.com/patents/US4901708?utm_source=gb-gplus-sharePatent US4901708 - Viewing laryngoscopeAdvanced Patent SearchPublication numberUS4901708 APublication typeGrantApplication numberUS 07/222,939Publication dateFeb 20, 1990Filing dateJul 22, 1988Priority dateJul 22, 1988Fee statusLapsedAlso published asCA2004139A1, CA2004139CPublication number07222939, 222939, US 4901708 A, US 4901708A, US-A-4901708, US4901708 A, US4901708AInventorsTzium-Shou LeeOriginal AssigneeLee Tzium ShouExport CitationBiBTeX, EndNote, RefManPatent Citations (7), Referenced by (30), Classifications (9), Legal Events (5) External Links: USPTO, USPTO Assignment, EspacenetViewing laryngoscope
US 4901708 AAbstract
A laryngoscope curved blade includes a pair of fiber optic bundles, one fiber optic bundle adapted to transmit light to the distal end of the blade and the other fiber optic bundle adapted to provide a viewing channel for telescopic viewing of the area adjacent to the distal end of the blade. A lens attached to the proximal end of the blade gathers and focuses the light transmitted by the viewing channel fiber optic bundle. Additionally, a lamp located on the proximal end of the blade provides illumination down the throat of a patient for line of sight viewing of the person performing the largyngoscope and the light transmitted by the first fiber optic bundle for illumination of the area adjacent to the distal end of the blade.
1. A laryngoscope which comprises a handle member adapted to receive batteries therein, a blade member having distal and proximal ends, means for attaching the proximal end of the blade member to the handle member, said blade member having a spatula portion curved longitudinally along its length and transversely across its width to provide an open bottom U-shaped tubulation and viewing channel along its length when inserted in the mouth of the user, a lamp member energized by batteries in the handle suspended from the proximal end of the blade member, below and facing said tubulation and viewing channel to illuminate for viewing and tubulation channel in the area between the distal and proximal ends of the spatula portion of said blade member, a first fiber optic bundle extending lengthwise on one leg of the tubulation an viewing channel from adjacent said lamp member and transmitting short of the distal end of the spatula to receive light from the lamp member and illuminate the area adjacent the distal end of the blade member, a lens on the proximal end of the blade member, a second fiber optic bundle extending lengthwise on the opposite leg of the channel terminating adjacent the distal end of the blade member beyond said first bundle to transmit the lighted view from adjacent said distal end to said lens, and said tubulation and viewing channel portion between the fiber optic bundles being unimpeded for tubulation and providing a clear sight path from the proximal end of the blade member along length of the spatula portion.
2. The laryngoscope of claim 1 including a wide dispersion lens on the distal end of the first fiber optic bundle to widely disperse the light emitted therefrom.
3. The laryngoscope of claim 1 including a second lens coupled to the distal end of the second fiber optic bundle to focus the light to the proximal end of the blade.
4. A laryngoscope blade member having proximal and distal ends with means at the proximal end for attachment to a battery carrying handle, a longitudinally elongated spatula portion between said ends, said spatula portion being transversely curved along its length to provide a viewing and tubulation channel which is open along its length, a lamp means suspended from the proximal end of the blade adapted to be energized from batteries in a handle attached to the blade and positioned to illuminate the tubulation channel in the area between the distal and proximal ends of the blade, a fiber optic bundle extending along one side of the channel for transmitting light from the lamp means to the area surrounding the distal end of the blade, and said lamp means and said bundle being positioned out of the viewing and tubulation portion of the channel to provide an unobstructed viewing and tubulation path along the length of the spatula portion.
5. The blade member of claim 4 including an upstanding leg means at the proximal end thereof mounting said lamp means below the viewing channel.
6. The laryngoscope of claim 4 including a second fiber optic bundle transmitting the view from the illuminated distal area of the spatula portion to the proximal end of the blade.
7. A laryngoscope blade having a proximal and distal ends and adapted to be affixed to a battery carrying laryngoscope handle member at its proximal end, said blade having a spatula portion between the proximal and distal ends of the blade, said spatula portion being curved longitudinally about its midpoint to embrace the tongue and throat of a user and also being curved transversely along its length to provide an open bottom viewing and tubulation channel with opposite sides, a lamp means attached to the proximal end of the blade adapted to be energized from batteries in the handle to illuminate the viewing and tubulation channel in the area between the distal and proximal end of the blade, a first fiber optic bundle along the length of the spatula portion at one side of the channel adapted to transmit light from the lamp means toward the distal end of the blade, a second fiber optic bundle attached along the length of the opposite side of the channel adapted to transmit the view from the light illuminated distal end portion of the blade to the proximal end of the blade, a viewing lens at the proximal end of the blade attached to said second optic bundle, and said first and second fiber optic bundles being positioned out of the path of said viewing and tubulation channel.
The present invention relates generally to medical diagnostic and surgical instruments and, in particular, to an improved laryngoscope including a blade incorporating fiber optic bundles thereon.
A human, like most vertebrates, has a plurality of internal passageways, tracts, tubes or pipes communicating between the mouth and the stomach or the lungs. The pharynx is a tract that extends from the nasal cavities to the larynx. The larynx is the upper part of the respiratory tract between the pharynx and the trachea, having cartilaginous walls and containing vocal cords enveloped in folds of mucous membranes attached to the sides. The trachea is a thin-walled tube of cartilaginous and membraneous tissue communicating between the larynx and the lungs to carry air to and from the lungs. The esophagus is a digestive tract communicating between the pharnyx in the area of the larynx and the stomach to carry food to the stomach.
The esophagus and trachea are positioned side-by-side and terminate in the area of the larynx. Thus, both food and air use the common pharynx between the mouth and the nasal cavities and the larynx area.
To prevent food from entering the larynx, a valve member called the epiglottis is provided on the outlet side of the larynx, just above the vocal cords. The epiglottis is a piece of leaf-like tissue composed of cartilage covered by mucous membrane and functions as a lid to cover the entrance to the larynx or voice organ during the act of swallowing. The mucous membrane of the epiglottis is loose and extends to the root (beginning) of the tongue. In doing so, it forms several folds. One that extends to the mid-line of the tongue is called median glosso epiglottic fold. A fold that goes to the side of the tongue is called the lateral glosso epiglottic fold. Between the median fold just described and the lateral fold, there is a natural depression or groove. This natural depression or groove is called the vallecula epiglottica, vallecula being a generic term for a shallow depression or groove. There is one such vallecula on each side of the median glosso epiglottic fold, i.e., a left and right vallecula.
A laryngoscope is a device that enables one to view into the larynx of a patient. Moreover, the laryngoscope assists in the intubulation or insertion of endoscopes down the trachea or esophagus of a patient by stretching the pharynx or throat sufficiently to permit passage of the endoscope while allowing viewing of the endoscope as it is inserted. Endoscopes are tubular instruments combining a light system and a telescopic system used in the visualization of the interior of a member such as an organ, and are adaptable for diagnostic, therapeutic and surgical procedures.
Laryngoscopes are formed of two main members: a handle member and a blade member. The handle member generally is a cylinder adapted to receive therein, batteries for powering a light source such as a lamp. The handle member includes an attaching or lock portion to which the blade member is operatively attached.
The blade member is generally one of two types: straight or curved. The curved type of a blade member is better suited for persons of normal anatomical configuration while the straight type blade member is better suited for persons with certain abnormally configured larynxes.
Either type of blade member includes a spatula portion and, generally, an upstanding leg portion. Each blade member is elongated and extends from a proximal end attached to the handle member to a distal end which is inserted into the patient's throat.
Laryngoscopy is the visual examination of the exterior and interior of the larynx by means of the laryngoscope. During a laryngoscopy, the blade of the laryngoscope is inserted into the throat or pharynx of the patient and the tip of the distal end of the blade is placed into the vallecula epiglottica, i.e., the depression formed at the base of the tongue and the epiglottis. With slight pressure, the blade causes the epiglottis to lift up, thereby exposing the larynx to the view of the medical professional performing the laryngoscopy.
Several features have been incorporated in the blade members to improve the viewing by the medical professional. On some blade members, the spatula includes a concave portion at the mid-portion to provide a tunnel along the length of the blade member through which the line of sight of the medical professional extends. Furthermore, lamps have been incorporated on some blade members to provide illumination into the interior of the patient's pharynx.
In some instances, the anatomical variations of the human throat are such that even when using a standard curved blade, the vocal cords can lie out of the direct vision line of the medical professional inserting the laryngoscope blade member. Thus, the medical professional will not have a clear view of the vocal cords when inserting the blade of a laryngoscope. This can be critical because the blade can be inserted such that the patient's throat is subject to trauma. Thus, it is highly desirable to provide a medical professional with the ability to view the area adjacent the distal end of a curved laryngoscope blade member so that trauma to the throat of a patient can be avoided.
In accordance with principles of the present invention, a laryngoscope is provided that enables a medical professional performing a laryngoscopy to have a clear view of the area adjacent the distal tip of a curved type laryngoscope blade member while inserting the blade member into the throat of a patient. To this end, fiber optic bundles are incorporated along a blade member, one fiber optic bundle transmitting light from a light source located near the proximal end of the blade member to a point along the distal end of the blade member and another fiber optic bundle being coupled to a lens located at the proximal end of the blade member to provide telescopic viewing of the area adjacent the distal end of the blade member.
By utilizing fiber optic bundles, it is possible to cause the transmission of light to occur around the bend of a curved blade. In this manner, irrespective of the physical location of the vocal cords or other anatomical features under examination, the area in proximity to the tip of the blade member is fully viewable.
Further, by appropriate placement of the fiber optic bundles, there is no interference with the normal view area along the spatula portion of the blade member. Additionally, the light source transmitting fiber optic bundle has a wide dispersion optic at its distal end so as to illuminate not only the area proximate to the distal end of the blade member, but to illuminate the throat of a patient along the normal line of sight of the user performing the laryngoscopy.
In one embodiment, the fiber optic bundles are placed at the sides of the blade member so as not to interfere with the normal tube passage channel formed by the concave tunnel down the center of the spatula portion of the blade member. In another embodiment, the fiber optic bundles are placed outside of the normal side reach of the blade member.
It is an object to provide an improved curved blade laryngoscope. It is another object to provide telescopic viewing of the area adjacent the distal end of a blade member of a curved blade laryngoscope.
It is a further object to provide illumination of the area adjacent the distal end of a blade member of a curved blade laryngoscope.
It is yet a further object to provide illumination of the area adjacent the distal end of a blade member of a curved blade laryngoscope that is dispersed widely.
FIG. 1 is a side elevational view of a laryngoscope embodying principles of the invention illustrating the performance of a laryngoscopy on a patient;
FIG. 2 is a side elevational view, partially broken away, of the laryngoscope of FIG. 1;
FIG. 3 is a partial proximal end view of the laryngoscope of FIG. 1 illustrating the proximal end of the blade member;
FIG. 4 is a cross-sectional view of the laryngoscope of FIG. 1 taken along the line IV--IV of FIG. 2; and
FIG. 5 is a fragmentary distal end view of the laryngoscope of FIG. 1 illustrating the distal ends of the fiber optic bundles.
The present invention provides a laryngoscope which allows for viewing around the bend of a curve blade member thus enabling viewing of the area adjacent the distal end of the blade member. To this end, fiber optic bundles are incorporated along a laryngoscope blade member, one bundle providing light transmission from a light source located near the proximal end near the blade member to the distal end of the blade member and another bundle coupled to a lens located at the proximal end of the blade member to provide telescopic viewing of the area adjacent the distal end of the blade member.
In FIG. 1 there is illustrated a cross-sectional view of a head 10 and a neck portion 12 of a human or patient positioned lying on his or her back. The patient is illustrated as being subjected to a laryngoscopy.
In the cross-sectional view, the patient's pharynx 14 (formed of nasal cavities 16 and mouth 18), tongue 20, epiglottis 22, esophagus 24, trachea 26, and larynx 28 are shown. Additionally shown is the patient's vallecula epiglottica 30, formed at the base of the tongue 20 and the epiglottis 22.
A laryngoscope 40, embodying principles of the invention and more fully illustrated in FIG. 2, is utilized in the laryngoscopy illustrated in FIG. 1. The laryngoscope 40 includes two basic members: a handle member 42 and a curved blade member 44.
As illustrated most fully in FIGS. 2 and 3, the handle member 42 includes an attaching or locking portion 48 to which the blade member 44 is operatively attached. Such handle members are readily available from a variety of manufacturers in the art.
The handle member 42 is cylindrically shaped and is adapted to receive batteries therein that provide a portable power source for the laryngoscope. The batteries are inserted into the handle member 42 by removal of a cover 48 located on one end of the handle member 42.
The blade member 44 includes a spatula portion 50 formed as an elongated member curved about a mid-point 52. The blade member 44 further includes an upstanding leg 54 which runs perpendicularly along one edge of the spatula member 50. The right angle formed by the upstanding leg 54 and the spatula member 50 is more clearly illustrated in FIGS. 3 and 4.
In FIGS. 3 and 4, it is illustrated that the spatula member 50 includes a concave channel 56 running along its length. The channel 56 is provided to allow a medical professional to have a greater line of sight view along the blade member 44 when performing a laryngoscopy and to provide a channel that accommodates a tubular portion of an endoscope, not illustrated.
As illustrated in FIGS. 2-5, the blade member 44 includes a pair of fiber optic bundles 60 and 62 affixed thereon. The fiber optic bundle 60 is adapted to transmit light produced by a lamp 64, operatively coupled to the batteries in the handle member 42, to the distal end of the blade member 44. The fiber optic bundle 62 is adapted to provide a telescopic viewing channel from the distal end to the proximal end of the blade member 44.
A lens member 66 and a lens member 68, located at opposite ends of the fiber optic bundle 62, cooperate to provide telescopic viewing. The lens 66 is located on the distal end of the fiber optic bundle 62 and serves to gather the light at that end and to focus it at the distal end of the bundle 62. A lens member 68 located at the proximal end of the blade member 44 gathers the light transmitted from the distal end of the blade member and expands it to provide an enlarged image at the proximal end of the blade member 44 for the person performing the laryngoscopy. Thus, the person performing the laryngoscopy enjoys a telescopic view of the area adjacent the distal end of the blade member 44.
As illustrated most clearly in FIGS. 4 and 5, the fiber optic bundles are positioned along the concave channel 56 of the spatula member 50. The fiber optic bundles 60 and 62 are small enough and spaced sufficiently far from each other so as not to block viewing along the spatula member 50 along the concave channel 56 or to block the space in the channel 56 through which the tubular member of an endoscope can be inserted.
Furthermore, as illustrated in FIG. 5, the fiber optic bundle 60 includes a lens 70 located on the distal end thereof to provide a wide dispersion of light to illuminate the throat of the patient, as well as the area in proximity to the distal end of the blade member 44.
As illustrated in FIG. 2, in the presently preferred embodiment, the fiber optic bundle 60 does not extend the full length of the blade member 44. The reason for this is that it is preferable to provide light at a point of the blade member 44 at which the light will not be fully covered by throat tissue upon insertion of the blade member 44 into the throat of the patient.
In use during the performance of a laryngoscopy, as illustrated in FIG. 1, the blade member 44 of the laryngoscope 40 is inserted into the mouth 18 of the patient. The blade member 44 supports the tongue 20 and opens the pharynx 14 to provide a line of sight down the throat of the patient for the person performing the laryngoscopy. As illustrated, the tip of the blade member 44 is inserted into the vallecula epiglottis 30, compression thereof causing the epiglottis 22 to raise up to expose the larynx 28 of the patient for viewing by the person performing the laryngoscopy. It can be appreciated that while the blade member 44 is being inserted into the vallecula epiglottica 30, the medical professional performing the laryngoscopy can view the area adjacent the tip of the blade member 44 through the eyepiece 66 and thus, ensure proper placement of the blade member 44 in the mouth 18 of the patient. By being able to view the area proximate to the tip of the blade member 44, the medical professional can ensure that the blade member 44 does not cause trauma or damage to the throat of the patient.
As is further illustrated in FIG. 1, the blade member described, provides two sources of light down the throat of the patient. The lamp member 64 provides light from the proximal end of the laryngoscope and, to a degree, illuminates the mouth and the pharynx of the patient. The light transmitted by fiber optic bundle 60 illuminates the area proximate to the distal end of the blade member 44.
Patent CitationsCited PatentFiling datePublication dateApplicantTitleUS2354471 *Aug 18, 1943Jul 25, 1944Foregger Company IncLaryngoscopeUS3091235 *Jun 15, 1960May 28, 1963American Optical CorpDiagnostic instrumentsUS3638644 *Mar 5, 1969Feb 1, 1972Michael ElbertIlluminated surgical speculumUS4086919 *Jul 9, 1976May 2, 1978Bullard James RLaryngoscopeUS4306547 *Nov 20, 1979Dec 22, 1981Lowell James RRigid fiberoptic laryngoscopeUS4583527 *Dec 24, 1984Apr 22, 1986Musicant Belmont SDisposable cushioning device for a laryngoscopeUS4592393 *Nov 27, 1984Jun 3, 1986Sulzer Brothers LimitedWeft thread preparation device* Cited by examinerReferenced byCiting PatentFiling datePublication dateApplicantTitleUS5060633 *Aug 31, 1990Oct 29, 1991Gibson Michael SLaryngoscope bladeUS5263472 *Aug 8, 1990Nov 23, 1993Ough Yon DLaryngoscope bladeUS5279281 *Sep 14, 1990Jan 18, 1994Harvey James CSingle-handed fibre-optic flexible laryngoscopeUS5287848 *May 21, 1993Feb 22, 1994Anthony CubbFor easy/accurate positioning of an endotrachael tube through vocal cordsUS5355870 *Jul 28, 1992Oct 18, 1994William LacyLaryngoscope having removable blade assembly containing lamp and light conductorUS5381787 *Mar 29, 1993Jan 17, 1995Bullard; James R.Extendable and retractable laryngoscopeUS5394863 *Jan 12, 1993Mar 7, 1995Sanford; Theodore H.Vaginal fornix illuminatorUS5800344 *Oct 23, 1996Sep 1, 1998Welch Allyn, Inc.Video laryngoscopeUS5873818 *Jan 23, 1998Feb 23, 1999Rothfels; Nancy LoisLaryngoscope with enhanced viewing capabilityUS5888195 *Mar 26, 1998Mar 30, 1999Schneider; Cary N.Laryngoscope bladeUS6623425Jul 23, 2001Sep 23, 2003Cartledge Medical Products, LlcModified laryngoscope blade to reduce dental injuries during intubationUS6840903Mar 21, 2002Jan 11, 2005Nuvista Technology CorporationLaryngoscope with image sensorUS7044910Aug 12, 2003May 16, 2006Cartledge Medical Products, Inc.Modified laryngoscope blade to reduce dental injuries during intubationUS7336833Jun 30, 2004Feb 26, 2008Given Imaging, Ltd.Device, system, and method for reducing image data captured in-vivoUS7801584May 2, 2004Sep 21, 2010Given Imaging Ltd.Panoramic field of view imaging deviceUS8251898Aug 7, 2008Aug 28, 2012Truphatek International LtdLaryngoscope apparatus with enhanced viewing capabilityUS8512234Apr 4, 2012Aug 20, 2013Truphatek International Ltd.Laryngoscope assembly with enhanced viewing capabilityUS8603105Jun 21, 2011Dec 10, 2013Lsi Solutions, Inc.Ergonomic, lighted uterine manipulator with cauteryUS8800566Oct 19, 2010Aug 12, 2014Ecolab Usa Inc.Airway devices, tube securing devices, and methods of making and using the sameUS8827899 *Sep 17, 2010Sep 9, 2014Vivid Medical, Inc.Disposable endoscopic access device and portable displayUS8858425Apr 13, 2010Oct 14, 2014Vivid Medical, Inc.Disposable endoscope and portable displayUS8878924Apr 30, 2010Nov 4, 2014Vivid Medical, Inc.Disposable microscope and portable displayUS20100121152 *Nov 3, 2009May 13, 2010Board Of Regents Of The University Of NebraskaSuction catheter assembly for a laryngoscopeUS20110028790 *Sep 17, 2010Feb 3, 2011Vivid Medical, Inc.Disposable endoscopic access device and portable displayUSRE37861 *Aug 31, 2000Sep 24, 2002Cary N. SchneiderLaryngoscope bladeCN100434032CNov 18, 2002Nov 19, 2008图发特克国际有限公司Light guide mount for use with a laryngoscopeDE102004028428A1 *Jun 3, 2004Jan 26, 2006Karl Storz Gmbh & Co. KgLaryngoskopEP1647296A1 *Oct 7, 2005Apr 19, 2006Machida Endoscope Co., LtdAirway tube guiding apparatusWO1994003101A1 *Jul 28, 1993Feb 17, 1994William LaceyLaryngoscope having removable blade assembly containing lampWO2003079889A1 *Mar 19, 2003Oct 2, 2003Nuvista Technology CorpLaryngoscope with image sensor* Cited by examinerClassifications U.S. Classification600/188, 600/199, 600/138International ClassificationA61B1/267Cooperative ClassificationA61B1/07, A61B1/267, A61B1/00195European ClassificationA61B1/267, A61B1/06Legal EventsDateCodeEventDescriptionApr 16, 2002FPExpired due to failure to pay maintenance feeEffective date: 20020220Feb 20, 2002LAPSLapse for failure to pay maintenance feesSep 11, 2001REMIMaintenance fee reminder mailedJul 24, 1997FPAYFee paymentYear of fee payment: 8Aug 12, 1993FPAYFee paymentYear of fee payment: 4RotateOriginal ImageGoogle Home - Sitemap - USPTO Bulk Downloads - Privacy Policy - Terms of Service - About Google Patents - Send FeedbackData provided by IFI CLAIMS Patent Services

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Census Bureau News -- Profile America Facts for Features: The Fourth of... -- WASHINGTON, May 14, 2013 /PRNewswire-USNewswire/ --
Census Bureau News -- Profile America Facts for Features: The Fourth of July 2013
WASHINGTON, May 14, 2013 /PRNewswire-USNewswire/ -- On this day in 1776, the Declaration of Independence was approved by the Continental Congress, setting the 13 colonies on the road to freedom as a sovereign nation. As always, this most American of holidays will be marked by parades, fireworks and backyard barbecues across the country.
(Logo: http://photos.prnewswire.com/prnh/20110428/DC91889LOGO) 2.5 million In July 1776, the estimated number of people living in the newly independent nation. Source: Historical Statistics of the United States: Colonial Times to 1970 http://www2.census.gov/prod2/statcomp/documents/HistoricalStatisticsoftheUnitedStates1789-1945.pdf 316.2 million The nation's estimated population on this July Fourth. Source: U.S. and World Population Clock http://www.census.gov/popclock/ The Signers 56 Numbers of signers to the Declaration of Independence. Benjamin Franklin, John Adams, Thomas Jefferson, Roger Sherman and Robert R. Livingston comprised the Committee of Five that drafted the Declaration. Jefferson, regarded as the strongest and most eloquent writer, wrote most of the document. It's also worth noting that:
John Hancock, President of the Second Continental Congress, was the first signer. This merchant by trade did so in an entirely blank space making it the largest and most famous signature – hence the term John Hancock, which is still used today as a synonym for signature. There are 7,354,043 businesses with paid employees in the U.S., according to the 2011 County Business Patterns. Benjamin Franklin (age 70), who represented Pennsylvania, was the oldest of the signers. Franklin County, Pa., had an estimated population of 151,275 as of July 1, 2012. Edward Rutledge (age 26), of South Carolina, was the youngest. Two future presidents signed, John Adams (second President) and Thomas Jefferson (third President). Both died on the 50th anniversary of signing the Declaration (July 4, 1826). There are 12 counties nationwide named Adams and 26 named Jefferson. Robert Livingston, who represented New York, was on the Committee of Five that drafted the Declaration of Independence but was recalled by his state before he could sign it. Livingston County, N.Y., was home to an estimated 64,810 people as of July 1, 2012. Representing Georgia in 1776 were Button Gwinnett, Lyman Hall and George Walton. Gwinnett County, Ga. (842,046), Hall County, Ga. (185,416) and Walton County, Ga. (84,575) were named for these signers. Charles Carroll, who represented Maryland, was the last surviving member of the signers of the Declaration. He died in 1832 at the age of 95. Carroll County, Md., named for him, had an estimated population of 167,217 as of July 1, 2012. Roger Sherman, who worked as a land surveyor and lawyer, represented Connecticut. Today, there are an estimated 30,445 surveyors, cartographers and photogrammetrists employed full time, year-round, and 840,813 lawyers employed full time, year-round nationwide, according to the 2011 American Community Survey. Nelson County, Va. (14,827) and Wythe County, Va. (29,251) were named for two of the six signers who represented the state of Virginia – Thomas Nelson Jr. and George Wythe. Sources: Annual Estimates of the Resident Population for Counties: April 1, 2010 to July 1, 2012 http://www.census.gov/popest/data/counties/totals/2012/CO-EST2012-01.html, 2011 American Community Survey http://factfinder2.census.gov/faces/tableservices/jsf/pages/productview.xhtml?pid=ACS_11_1YR_B24124&prodType=table and 2011 County Business Patterns (NAICS) http://censtats.census.gov/cgi-bin/cbpnaic/cbpsect.pl Fireworks
$218.2 million The value of fireworks imported from China in 2012, representing the bulk of all U.S. fireworks imported ($227.3 million). U.S. exports of fireworks, by comparison, came to just $11.7 million in 2012, with Israel purchasing more than any other country ($2.5 million).
$231.8 million The value of U.S. manufacturers' shipments of fireworks and pyrotechnics (including flares, igniters, etc.) in 2007. Source: 2007 Economic Census, Series EC0731SP1, Products and Services Code 325998J108 http://www.census.gov/econ/census07/ Flags
$3.8 million In 2012, the dollar value of U.S. imports of American flags. The vast majority of this amount ($3.6 million) was for U.S. flags made in China. Source: Foreign Trade Statistics http://www.census.gov/foreign-trade/www/ http://www.usatradeonline.gov
$614,115 Dollar value of U.S. flags exported in 2012. Mexico was the leading customer, purchasing $188,824 worth. Source: Foreign Trade Statistics http://www.census.gov/foreign-trade/www/ http://www.usatradeonline.gov
$302.7 millionDollar value of shipments of fabricated flags, banners and similar emblems by the nation's manufacturers in 2007, according to the latest published economic census statistics. Source: 2007 Economic Census, Series EC0731SP1, Products and Services Code 3149998231 http://www.census.gov/econ/census07/ Patriotic-Sounding Place Names Fifty-nine places contain the word "liberty" in the name. Pennsylvania, with 11, has more of these places than any other state. Of the 59 places nationwide containing "liberty" in the name, four are counties: Liberty County, Ga. (65,471), Liberty County, Fla. (8,276), Liberty County, Mont. (2,392) and Liberty County, Texas (76,571).
One place has "patriot" in its name. Patriot, Ind., has an estimated population of 209.
The most common patriotic-sounding word used within place names is "union" with 136. Pennsylvania, with 33, has more of these places than any other state. Other words most commonly used in place names are Washington (127), Franklin (118), Jackson (96) and Lincoln (95).
Sources: TIGER Shapefiles, the Census Bureau's geographic database (Place/MCD/County combined "used within name" count), Annual Estimates of the Resident Population for Incorporated Places: April 1, 2010 to July 1, 2011 http://www.census.gov/popest/data/cities/totals/2011/SUB-EST2011-3.html The British are Coming!
$109.8 billion Dollar value of trade last year between the United States and the United Kingdom, making the British, our adversary in 1776, our sixth-leading trading partner today. Source: Foreign Trade Statistics http://www.census.gov/foreign-trade/statistics/highlights/top/top1112yr.html#total
65.9 millionNumber of all hogs and pigs on March 1, 2013. Chances are that the pork hot dogs and sausages consumed on the Fourth of July originated in Iowa. The Hawkeye State was home to 20.3 million hogs and pigs. North Carolina (8.9 million) and Minnesota (7.8 million) were also homes to large numbers of pigs. Source: USDA National Agricultural Statistics Service, http://usda01.library.cornell.edu/usda/current/HogsPigs/HogsPigs-03-28-2013.pdf 6.3 billion pounds Total estimated production of cattle and calves in Texas in 2012. Chances are good that the beef hot dogs, steaks and burgers on your backyard grill came from the Lone Star State, which accounted for nearly one-sixth of the nation's total production. And if the beef did not come from Texas, it very well may have come from Nebraska (estimated at5.1 billion pounds) or Kansas (estimated at 3.8 billion pounds).Source: USDA National Agricultural Statistics Service http://usda01.library.cornell.edu/usda/current/MeatAnimPr/MeatAnimPr-04-25-2013.pdf 6 Number of states in which the value of broiler chicken production was estimated at $1 billion or greater between December 2011 and November 2012. There is a good chance that one of these states — Georgia, Arkansas, North Carolina, Alabama, Mississippi or Texas — is the source of your barbecued chicken.Source: USDA National Agricultural Statistics Service http://usda01.library.cornell.edu/usda/current/PoulProdVa/PoulProdVa-04-29-2013.pdf 345 million Acreage planted of potatoes in Idaho in 2012, the most in the nation. Washington followed with 165 million acres. The total 2012 potato crop is forecast to exceed 467 million hundredweight (cwt), the highest level since 2000 when 523 million cwt was produced. Potato salad is a popular food item at Fourth of July barbecues. Source: USDA, National Agriculture Statistics Service, Economic Research Service http://usda01.library.cornell.edu/usda/current/CropProdSu/CropProdSu-01-11-2013.pdf http://www.ers.usda.gov/publications/vgs-vegetables-and-pulses-outlook/vgs353.aspx How Do We Know?
As we celebrate this Independence Day, we reflect on how our Founding Fathers enshrined the importance of statistics in our Constitution as a vital tool for measuring our people, places and economy. Since 1790, the U.S. Census has been much more than a simple head count; it has charted the growth and composition of our nation. The questions have evolved over time to address our changing needs. Today, the 10-year census, the economic census and the American Community Survey give Congress and community leaders the information they need to make informed decisions that shape our democracy. These statistics are how we know how our country is doing.
Visit http://www.census.gov/how to view and to learn more about "How Do We Know?" Follow @uscensusbureau on Facebook, Twitter, Flickr, YouTube and Pinterest (#HowDoWeKnow) for updates.
Earth Day (April 22) (November) Asian/Pacific American Heritage Month (May) Veterans Day (Nov. 11) Older Americans Month (May) Thanksgiving Day Cinco de Mayo (May 5) The Holiday Season (December) Mother's Day Hurricane Season Begins (June 1) Father's Day The Fourth of July (July 4) Anniversary of Americans with Disabilities Act (July 26) Back to School (August) Editor's note: The preceding data were collected from a variety of sources and may be subject to sampling variability and other sources of error. Facts for Features are customarily released about two months before an observance in order to accommodate magazine production timelines. Questions or comments should be directed to the Census Bureau's Public Information Office: telephone: 301-763-3030; fax: 301-763-3762; or e-mail: <PIO@census.gov>.
More by this Source Per Pupil Spending Varies Heavily Across the United States
Census Bureau 2014 Characteristics of New Housing
Jun 01, 2015, 10:59 ET

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Glycine increases glyoxalase-1 function by promoting Nrf2 translocation into the nucleus of kidney cells of streptozotocin-induced diabetic rats. - PubMed - NCBI
1 selected item: 30825261
Wang Z1, Zhao D1, Chen L1, Li J1, Yuan G1, Yang G2, Zhang H1, Guo X1, Zhang J1.
Endocrinology, Peking University First Hospital, 8 Xishiku Street, Xicheng District, Beijing, 100034, China.
Animal Center, Peking University First Hospital, 8 Xishiku Street, Xicheng District, Beijing, 100034, China.
We have previously reported that glycine suppresses the advanced glycation end-products (AGEs) signaling pathway and mitigates subsequent oxidative stress in the kidney of diabetic rats. In the present study, we investigated whether this beneficial effect was associated with up-regulation of glyoxalase-1 (Glo1) and activation of the nuclear factor erythroid 2-related factor 2 (Nrf2).
Both healthy rats and streptozotocin-induced diabetic rats were administrated with glycine (1% added to the drinking water) for 12 weeks. The function of Glo1, mRNA and protein expressions of Nrf2, and markers of oxidative status were measured in the kidney. The mRNA expressions of other downstream signaling molecules of Nrf2 pathway were also determined.
The mRNA and protein expressions as well as the activity of Glo1 were decreased in the kidneys of diabetic rats, accompanied by diminished GSH levels. After glycine treatment, these parameters of Glo1 function were markedly increased. Comparing with the control group, the levels of Nrf2 mRNA and protein in the total kidney lysis were both markedly elevated in the diabetic group and glycine-treated group. However, the nuclear translocation of Nrf2 was significantly increased in the glycine-treated group than in the diabetic group. In addition, the antioxidant capacity and the expressions of other downstream molecules of the Nrf2 signaling pathway were significantly increased after glycine treatment.
Our study demonstrates that glycine might enhance the function of Glo1 and restore antioxidant defense by promoting the nuclear translocation of Nrf2, thus inhibiting AGEs formation and protecting against renal oxidative stress. This article is protected by copyright. All rights reserved.
glycine; glyoxalase-1; nuclear factor erythroid 2-related factor 2
10.1111/jdi.13032

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Jagger Junior and a girl who looks just like Jerry | Daily Mail Online
Jagger Junior and a girl who looks just like Jerry By CLEMMIE MOODIELast updated at 00:05 30 November 2007As an up and coming actor, James Jagger is well versed in the art of imitation. Even, it seems, when it comes to his taste in women. Standing side by side, the 21-year-old and his new girlfriend, Alice Devall, bore a strong similarity to his parents, Sir Mick Jagger and Jerry Hall. While Jagger junior replicated his father's famous stare, his 19-year-old date looked remarkably like her boyfriend's 51-year-old mother. Scroll down for more...
The couple were pictured at the British Independent Film Awards held in London on Wednesday night. An onlooker said: "They seemed really relaxed in each other's company. "James has honed his dad's iconic facial expressions down to a tee. Alice is the absolute spit of Jerry at that age. Scroll down for more...
"Seeing the two of them together is quite surreal as they really do look so much like a young, perhaps slightly edgier, Mick and Jerry." James recently made his stage debut in London and both his 64-year-old father and Miss Hall, who separated from the Rolling Stone singer in 1999, went to see him. Share or comment on this article

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text: Scores for August 7, 2009Auto Update: OffAugust 2, 2009 - August 8, 2009 Sun 2 15 gmsMon 3 9 gmsTue 4 15 gmsWed 5 15 gmsThu 6 11 gmsFri 7 15 gmsSat 8 15 gms More ScoreboardsNFLNBAMLBNHLNCAA FootballNCAAM BasketballTennisAll ScoresScoreboard ToolsDaily LinesESPN AlertsMinimize ScoreCenter Video [-]Watch ScoreCenter Video [+]Cardinals Walk Off In 13thBaseball Tonight Spotlight: Tony Cruz's RBI single in the 13th lifted the Cardinals to a 3-2 win over the Brewers, who seem to be letting their playoff opportunity slip away.Tags: MLB, Milwaukee Brewers, St. Louis Cardinals, Tony Cruz, Matt AdamsCardinals Walk Off In 13thVIDEO PLAYLIST Cardinals Walk Off In 13thCardinals Walk Off In 13thBaseball Tonight Spotlight: Tony Cruz's RBI single in the 13th lifted the Cardinals to a 3-2 win over the Brewers, who seem to be letting their playoff opportunity slip away.Tags: MLB, Milwaukee Brewers, St. Louis Cardinals, Tony Cruz, Matt AdamsDodgers Rally Past CubsDodgers Rally Past CubsThe Dodgers scored five runs in the top of the seventh to complete the 8-4 comeback against the Cubs.Tags: MLB, Los Angeles Dodgers, Chicago Cubs, Jorge Soler, Andre Ethier, Dee Gordon, Yasiel PuigRangers Sweep A'sRangers Sweep A'sThe Rangers beat the A's 7-2 for their sixth straight win.Tags: MLB, Texas Rangers, Oakland Athletics, Tomas TelisAthletics' Woes ContinueAthletics' Woes ContinueThe "Baseball Tonight" crew breaks down what the Athletics need to do to break out of their slump.Tags: MLB, Oakland Athletics

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Someguy46 comments on What are some interesting facts about the human body that are not widely known?jump to contentmy subredditsannouncementsArtAskRedditaskscienceawwblogbookscreepydataisbeautifulDIYDocumentariesEarthPornexplainlikeimfiveFitnessfoodfunnyFuturologygadgetsgamingGetMotivatedgifshistoryIAmAInternetIsBeautifulJokesLifeProTipslistentothismildlyinterestingmoviesMusicnewsnosleepnottheonionOldSchoolCoolpersonalfinancephilosophyphotoshopbattlespicsscienceShowerthoughtsspacesportstelevisiontifutodayilearnedTwoXChromosomesUpliftingNewsvideosworldnewsWritingPromptsedit subscriptionsfront-all-random | AskReddit-funny-pics-todayilearned-videos-news-gifs-worldnews-movies-gaming-aww-Showerthoughts-mildlyinteresting-IAmA-explainlikeimfive-Jokes-Music-nottheonion-tifu-television-science-TwoXChromosomes-DIY-Futurology-LifeProTips-OldSchoolCool-space-Fitness-photoshopbattles-food-askscience-GetMotivated-UpliftingNews-personalfinance-Documentaries-sports-books-dataisbeautiful-WritingPrompts-Art-nosleep-EarthPorn-InternetIsBeautiful-history-creepy-gadgets-listentothis-philosophy-announcements-blogmore » AskRedditcommentsrelatedWant to join? Log in or sign up in seconds.|Englishlimit my search to /r/AskReddituse the following search parameters to narrow your results:subreddit:subredditfind submissions in "subreddit"author:usernamefind submissions by "username"site:example.comfind submissions from "example.com"url:textsearch for "text" in urlselftext:textsearch for "text" in self post contentsself:yes (or self:no)include (or exclude) self postsnsfw:yes (or nsfw:no)include (or exclude) results marked as NSFWe.g. subreddit:aww site:imgur.com dogsee the search faq for details.advanced search: by author, subreddit...this post was submitted on 30 Sep 20132,087 points (90% upvoted)shortlink: remember mereset passwordloginAsk A New QuestionAskRedditunsubscribesubscribe10,414,728 readers25,126 users here now [ SERIOUS ] Rules:
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208620872088What are some interesting facts about the human body that are not widely known? (self.AskReddit)submitted 2 years ago by dzownzer8517 commentsshareloading...sorted by: besttopnewcontroversialoldrandomq&ayou are viewing a single comment's thread.view the rest of the comments →[–]Someguy46 1 point2 points3 points 2 years ago (1 child)You mean the bugs living in your eyelashes?
permalinkembedsaveparentgive gold[–]nagsnyder 0 points1 point2 points 2 years ago (0 children)My eyes... they itch.
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Personal Tech One Number to Ring Them All
Stuart Goldenberg If Google search revolutionized the Web, and Gmail revolutionized free e-mail, then one thing’s for sure: Google Voice, unveiled Thursday, will revolutionize telephones.It unifies your phone numbers, transcribes your voice mail, blocks telemarketers and elevates text messages to first-class communication citizens. And that’s just the warm-up.Google Voice began life in 2005 as something called GrandCentral. It was, in its own way, revolutionary.It was intended to solve the headaches of having more than one phone number (home, work, cellphone and so on): Having to check multiple answering machines. Missing calls when people try to reach you on your cell when you’re at home (or the other way around). Sending around e-mail at work that says, “On Thursday from 5 to 8:30, I’ll be on my cell; for the rest of the weekend, call me at home.” And having to change phone numbers when you switched jobs or cities. Continue reading the main story
No longer did people have to track you down by dialing multiple numbers; no matter where you were, your uni-number found you. And all voice mail messages landed in a single voice mail box, on the Web. (You could also dial in to hear them as usual.)On the Web, you could play back your messages or even download them as audio files to preserve for posterity. You could even ask to be notified of new voice mail by e-mail.But wait, there was more. Each time you answered a call, while the caller was still hearing “one ringy-dingy, two ringy-dingies,” you heard a recording offering four ways to handle the call: “Press 1 to accept, 2 to send to voice mail, 3 to listen in on voice mail, or 4 to accept and record the call.” If you pressed 3, the call went directly to voice mail, but you could listen in. If you felt that the caller deserved your immediate attention, you could press * to pick up and join the call. This subtle feature saved time, conserved cellular minutes and, in certain cases, avoided a great deal of interpersonal conflict.GrandCentral also let you record a different voice mail greeting for each person in your address book: “Hey, dollface, leave me a sweet nothing” for your love interest, “Hi, boss, I’m out making us both some money” for your employer.You could also specify which phones would ring when certain people called. (For the really annoying people in your life, you could even tell GrandCentral to answer with the classic, three-tone “The number you have dialed is no longer in service” message.)Also very cool: Any time during a call, you could press the * key to make all of your phones ring again, so that you could pick up on a different phone in midcall. If you were heading out the door, you could switch a landline call to your cellphone.GrandCentral also offered telemarketing spam filters, off-hour call blocking (“never ring my BlackBerry on weekends”), and a dizzying number of other functions. For people with complicated lives, GrandCentral was a breath of fresh air. It felt like a secret power that nobody else had.Then, in 2007, Google bought GrandCentral. It stopped accepting new members, ceased any visible work on it, and, apparently, forgot about it completely. The early adopters, several hundred thousand of them, were able to keep using GrandCentral’s features. But as time went on, their hearts sank. In January, Salon.com summed it up in an editorial called, “Will the Last One to Leave GrandCentral Please Turn Out the Lights?”
As it turns out, the joke was on them. Google was quietly working on GrandCentral all along. Starting Thursday, existing GrandCentral members can upgrade to Google Voice. In a few weeks, after debugging the system, Google will open the service to all.Google Voice starts with a clean, redesigned Web site that looks like an in-box, à la Gmail. It maintains all of those original GrandCentral features — but more important, introduces four game-changing new ones.
FREE VOICE MAIL TRANSCRIPTIONS From now on, you don’t have to listen to your messages in order; you don’t have to listen to them at all. In seconds, these recordings are converted into typed text. They show up as e-mail messages or text messages on your cellphone.This is huge. It means that you can search, sort, save, forward, copy and paste voice mail messages.No human effort is involved; it’s all done with software. As a result, the transcriptions are rarely perfect. For one thing, Google’s software doesn’t seem to have discovered punctuation yet. (“ohh hi it’s michelle i just wanted to let you know that i really had fun last night and it’s really great to see you okay talk to you later bye bye.”)There are errors, of course; it’s hard enough for people to understand cellphone conversations, let alone computers. Cleverly enough, the Web site displays transcribed words more faintly (light gray) when it is less confident about the transcription. Fortunately, it generally nails numbers — phone numbers, arrival times, addresses. And the rest is accurate enough to convey the gist.Companies like PhoneTag, Callwave and Spinvox already transcribe voice mail, complete with punctuation. They’re great, but they cost money. Google Voice is free.FREE CONFERENCE CALLING Never again will you pay for a conference call, or require a special dial-in number, or mess around with access codes. All you do is tell your friends to call your GrandCentral at the specified time — and boom, you can conference them in as they call you. No charge.DIRT-CHEAP INTERNATIONAL CALLS If you dial your own Google Voice number from one of your phones, you’re offered an option to call overseas at rates even lower than Skype’s (and much lower than your cellphone company’s): 2 cents a minute to France or China, 3 cents to Chile or the Czech Republic. Sweet.TEXT MESSAGE ORGANIZATION Google Voice’s last feature is its most profound. The old GrandCentral wasn’t great with text messages sent to your uni-number. In fact, it ignored them. They just disappeared.
Google Voice, however, does the right thing: it sends text messages to whichever cellphones you want — even multiple phones simultaneously.Even more important, it collects them in your Web in-box just like e-mail. You can file them, search them and, for the first time in cellphone history, keep them. They don’t vanish forever once your cellphone gets full.You can also reply to them with a click, either with a call or another text; your back-and-forths appear online as a conversation.Google Voice eliminates some of the annoyances of its predecessor. You can, if you wish, turn off that “press 1, press 2” option, so when the phone rings, you can just pick it up and start talking. Google has also done some Googlish integration; for example, your Gmail and Google Voice address books are the same.Nitpicks? Sure. The service has vastly beefed up its selection of available uni-numbers, but there are still some area codes you can’t get (212 is especially rare). As a side effect of Google Voice’s ring-all-phones-at-once technology, you sometimes find fragments of Google Voice error recordings on the answering machines of the phones you didn’t answer. (Solution: make your voice mail greeting at least 15 seconds long.) There’s a learning curve to all of this, too.
Still, you can’t imagine how much the game changes when you have a single phone number, voice mail transcriptions and nondeleting text messages on every phone. Suddenly, your communications are not only unified, but they’re unified everywhere at once — the cellphone, the Web and the e-mail program. And all of it free — even ad-free.There may be some fallout as a result; I’d hate to be a company that sells voice mail transcription or conferencing calling services right about now. But that’s life, right? Every now and then, a little revolution is good for us.
A version of this article appears in print on , on Page B1 of the New York edition with the headline: One Number To Ring Them All. Order Reprints| Today's Paper|Subscribe
Google Voice May Threaten Other Phone Services

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Danyan Gao - Semantic Scholar
Jiapei Lv, Danyan Gao, Yong Zhang, Duojiao Wu, Lihua Shen, Xiangdong Wang
Lung cancer is a leading cause of cancer-related deaths with an increasing incidence and poor prognoses. To further understand the regulatory mechanisms of lipidomic profiles in lung cancer subtypes,… (More)
William G. J. Wang, Danyan Gao, Xiangdong Wang
There is a rapid increase of evidence to address the importance of the interaction between single cells, drugs, and the response of single cells to therapies. Single-cell measurements were used to… (More)
Mitochondrial DNA Methylation and Related Disease.
Danyan Gao, Bijun Zhu, Hongzhi Sun, Xiangdong Wang
Most researchers focused on methylation of genomic DNA, while methylation of mitochondrial DNA (mtDNA) is rarely tauched, and there is still controversy about the existence of mtDNA methylation. The… (More)
Genetic variations in COPD and lung cancer may be one of the molecular mechanisms responsible for COPD-lung cancer transformation. The present review highlights main genetic variations co-existed in… (More)
Roles of NIPBL in maintenance of genome stability.
Danyan Gao, Bijun Zhu, Xin Cao, Miaomiao Zhang, Xiangdong Wang
A cohesin-loading factor (NIPBL) is one of important regulatory factors in the maintenance of 3D genome organization and function, by interacting with a large number of factors, e.g. cohesion,… (More)

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gov.uscourts.wied.63043 : Free Download & Streaming : Internet Archive
gov.uscourts.wied.63043 Identifier gov.uscourts.wied.63043Assigned-to Judge Rudolph T RandaCase-name USA v. Decryption of a Seized Data Storage SystemCourt wiedDate-case-filed 2013-04-03Date-case-terminated 2013-09-09Date-last-filing 2013-09-09Docket-num 2:13-mj-00449Mediatype textsPacer-case-num 63043
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gov.uscourts.ohsb.39459 Jun 17, 2010
gov.uscourts.pawd.95449 Jun 11, 2010
gov.uscourts.mdd.27640 Feb 20, 2011
gov.uscourts.mad.94566 Mar 24, 2010

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Grand Palladium Bavaro Resort & Spa (Punta Cana, Dominican Republic) - Resort (All-Inclusive) Reviews - TripAdvisor
Grand Palladium Bavaro Resort & Spa Resort (All-Inclusive), Punta Cana
2,700 traveler photos
Dutch first English first French first German first Italian first Polish first Portuguese first Russian first Spanish first Any dboo1111
More rmcm1
I was at the hotel and never saw anything like it. dirty room upon arrival, door lock broken and have not solved the problem, only after a complaint is resolved. to mention that I had to go the reception 20 times and even told me to go try the door was gone. average quality meals and always equal to the...
Dear Rmcm1,
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About TripAdvisor® TripAdvisor™ provides reviews, articles, recommendations and opinions on Grand Palladium Bavaro Resort & Spa, Punta Cana.


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Five to follow: Cheltenham & Aintree | We Have A Dream among Saturday stars in action
Five-year-olds haven’t the best record in Champion Hurdles, Katchit being the last horse to return victorious over a decade ago - and he was the first horse from that age group to prevail in 23 years ... His final victory at Aintree saw him dispose of Apple’s Shakira, previously thought to be the Henderson first string, by 17 lengths, a powerful turn of foot taking him well clear by the line ... Loves Cheltenham (especially the Old Course!)....
The 39-year-old Finn’s victory for Ferrari in Sunday’s US Grand Prix ended a winless run of 113 races dating back to victory with Lotus in Australia in March 2013 ... While Italian Riccardo Patrese waited six years and seven months and 99 races between his 1983 South African Grand Prix victory and 1990 San Marino win, Raikkonen has set a record for most races between wins ... "I’m proving [to] people certain things ... It’s just a number....
Top stars for Panasonic Open
Kapur topped the inaugural Panasonic Swing ranking with total points of 2922.90 last year, thanks largely to his victory at the Panasonic Open India, which was his first Asian Tour victory on home soil and second win in 2017. The 36-year-old Indian went on to win his fourth Asian Tour title at the Royal Cup in Thailand one ......
BC-SOC--Monza-Brocchi
Eds ... Monza is without a victory since then and hired Brocchi to replace the fired Marco Zaffaroni ... Monza announced on Monday that it had fired Marco Zaffaroni and replaced him with the 42-year-old Brocchi. Having won its first three matches of the season, Monza is without a victory since Berlusconi's takeover — losing three and drawing the other two ... ——— ... .......
Manchester United manager Jose Mourinho has warned his players of the burning desire that Cristiano Ronaldo will have to secure a victory over them at Old Trafford with Juventus ... On that occasion, he found the net and the Portuguese manager believes that the 33-year-old’s desire to do so again will remain enormous ... at Old Trafford earlier this month....
BC-FBN--Buccaneers-Alexander
The fourth-year pro was injured during the first half of a 26-23 overtime victory over the Cleveland Browns. An MRI confirmed the 24-year-old has a torn anterior cruciate ligament in his left knee ... The fourth-year pro was injured during the first half of Sunday's 26-23 overtime victory over the Cleveland Browns....
Have Spurs missed out on huge opportunity to sign �90k-per-week PL star?
The Times reported in August that Martial was desperate to leave the Old Trafford club. The Frenchman started only 18 league matches and missed out on a place in France’s victorious World Cup squad as a result. The 22-year-old joined Manchester United in 2015 for a deal worth around £57.6 million ... From Sportslens.com - Football News . Football Blog ....
The fourth-year pro was injured during the first half of Sunday's 26-23 overtime victory over the Cleveland Browns....
Wolves' Wiggins exits with quad injury
Wiggins did not return to the Timberwolves' 101-91 victory over the Indiana Pacers in Minneapolis. The 23-year-old played eight minutes, scoring two points and handing out one assist ... ....
Monza announced on Monday that it had fired Marco Zaffaroni and replaced him with the 42-year-old ......
Jose Mourinho says Manchester United's clash against Juventus is no 'nightmare'
United drew 2-2 with Chelsea in the Premier League on Saturday, and are now preparing to welcome Juve to Old Trafford on Tuesday night. Victory for United would see them overtake Juventus at the top of Group F, and Mourinho is in confident mood as he takes on the Italians for the first time in a European competition ... Ronaldo's first return to Old Trafford....
Ozil scored the Gunners' equaliser at Emirates Stadium before playing key roles in two sublime team moves that ended with Pierre-Emerick Aubameyang finding the net to secure a 3-1 victory. The 30-year-old, who was captain for the match, became the top-scoring German in Premier League history with his 30th goal in the competition to help his side battle back from Bellerin's first-half own goal ... Wunderbar ... ....
Formula One teams usually bring upgrades to races but Ferrari opted for a ‘downgrade’ at the U.S. Grand Prix and it turned out to be a winner ... “It took too long,” the German said about the car’s recovered performance. “You can see it as good news but you can also see it as bad news ... Raikkonen’s win was the 39-year-old Finn’s first since 2013, a record gap of 113 races between victories ... ....

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Summer Women V Neck Floral Short Sleeve Dress Party Beach Side Split Sundress | eBay
AU Summer Women V Neck Short Sleeve Long Dress Party Beach Split Sundress S-2XL
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Brand: Unbranded Occasion 1: Cocktail / Formal / Casual / Party / Outdoor / Holiday
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Summer/Beach Short Sleeve Floral Tops for Women,
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value: This website is an American multinational e-commerce corporation based in San Jose, California, that facilitates consumer-to-consumer and business-to-consumer sales through its website.


text:
(Redirected from The Man Who Came to Dinner (1942 film))
Finally fed up with Whiteside's shenanigans, insults, and unbearable personality, and realizing that he has been "faking" his injuries for quite some time, Mr. Stanley orders him to leave. Before he does, Whiteside blackmails him into allowing his children to do as they please by threatening to reveal Stanley's sister Harriet's past

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3 bedroom detached house for sale in Bix, Henley-on-Thames, Oxfordshire, RG9, RG9
www.rightmove.co.uk/property/62599851
Henley-on-Thames (2.0 mi)
Shiplake (3.7 mi)
Wargrave (4.6 mi)
Disclaimer - Property reference HEN140076. The information displayed about this property comprises a property advertisement. Rightmove.co.uk makes no warranty as to the accuracy or completeness of the advertisement or any linked or associated information, and Rightmove has no control over the content. This property advertisement does not constitute property particulars. The information is provided and maintained by Ballards Estate Agents , Henley On Thames. Please contact the selling agent or developer directly to obtain any information which may be available under the terms of The Energy Performance of Buildings (Certificates and Inspections) (England and Wales) Regulations 2007 or the Home Report if in relation to a residential property in Scotland.
31 Oct 2003 Lambridge Wood Barn Bix, RG9 £750,000
15 Jul 1999 Lambridge Wood House Bix, RG9 £850,000

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Bracelet woven miyuki 15/0 very fine Royal Blue and silver on
Bracelet woven miyuki 15/0 very fine Royal Blue and silver on magnetic clasp
Bracelet woven on loom with size 15/0 blue and silver Miyuki seed beads.
Weaving measures 1.9 cm in width and 15 cm in length. It is finished with silver ferrules and a magnetic clasp.
It fits wrists ranging from 15 to 17 cm in diameter.

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Strength and Conditioning, Part IVBuck Sanders07/19/2001The top five in the power clean on the UNC football team. Results just in.The top five in the power clean testing are:
1) James Faison, So. -- 374 (a new overall UNC record)
2) Will Chapman, So. - 364 (record for UNC defensive tackles, breaking record of Ric Terry)
3) Madison Hedgecock, Rfr. - 364 (bested previous mark for UNC fullbacks)
4) Joey Evans, Sr. -- 358 (bests previous mark of Ebenezar Ekuban)
5) Julius Peppers, Jr.-- 358 (ties with Evans for best defensive end mark all-time)
Coach Connors says that the power clean, the vertical leap, and the forty speed are the most significant areas of testing in strength and conditioning. Share on Facebook Share on TwitterTrending on ScoutThis Week with Mike FoxICTV: Berry's Takeaways from UVaPhotos: Heels Drop Physical Affair2019 Target: Garrett ShraderFirst Report: UNC Coughs Up LossInside Carolina Top StoriesPerspective in LossUNC won 10 straight after a late-season loss at Virginia last season.by Greg BarnesInside Carolina7:50 PMUNC-UVa: Roy Williams PostgameUNC's head coach spoke to reporters following his team's 53-43 loss at Virginia on Monday.by Evan ChronisInside Carolina6:51 PMBreaking NewsFirst Report: UNC Coughs Up LossUNC fell to 25-6 (13-4 ACC).by Greg BarnesInside Carolina5:17 PMThis Week with Mike FoxInside Carolina caught up with Tar Heels skipper Mike Fox after UNC swept Radford. The Tar Heels are 7-0 heading into two mid-week games (Winthrop, St. John's) before hosting Long…by Matt ClementsInside Carolina1:33 PMNew Faces at Skill PositionsThe wide receiver and running back depth chart are two of the biggest unknowns entering spring practice.by Buck SandersInside Carolina8:39 AMEstablishing Defensive IdentityNew Tar Heel coordinator has worked with a number of heralded defensive minds.by Buck SandersInside Carolina8:12 AMICTV: Berry's Takeaways from UVaJoel Berry talks to media following loss to Virginia Monday night.by Lindsey SparrowInside Carolina7:02 PMICTV: Jackson Talks ExecutionJustin Jackson tied his season low Monday night with 7 points.by Lindsey SparrowInside Carolina6:40 PMPhotos: Heels Drop Physical AffairCHARLOTTESVILLE, Va. -- North Carolina struggled with its quick ACC road trip turnaround and was out-slugged by the Wahoos.by Jim HawkinsInside Carolina5:51 PM2019 Target: Garrett ShraderAlthough not originally from NC, the in-state passer has several connections to UNC.by Don CallahanInside Carolina8:57 AMPodcast: Spring Football PreviewBuck Sanders and Greg Barnes join host Tommy Ashley to preview Carolina Football's spring practice season. The Tar Heels start practice on Tuesday and end with the Spring Game on…by Tommy AshleyInside Carolina5:58 AMUNC Impresses Simmons, His ParentsThe Philly receiver made his third visit to UNC.by Don CallahanInside Carolina4:10 AMLoad More

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ZAO RSKHB - Strakhovaniye Insurance Company: Private Company Information - Bloomberg
February 25, 2018 10:03 AM ET
ZAO RSKHB - Strakhovaniye Insurance Company offers insurance services. The company was formerly known as ZAO GazGarant Insurance Company. The company was founded in 2011 and is based in Moscow, Russia. As of March 3, 2015, ZAO RSKHB - Strakhovaniye Insurance Company operates as a subsidiary of Open Joint Stock Company Russian Agricultural Bank.
pereulok Gagarinskijj, 3
7 495 213 0857
Ms. Irina Zhachkina
To contact ZAO RSKHB - Strakhovaniye Insurance Company, please visit www.rshbins.ru. Company data is provided by S&P Global Market Intelligence. Please use this form to report any data issues.

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Watauga County, North Carolina	From FamilySearch Wiki	(Difference between revisions)	Jump to:	navigation	, search	Revision as of 19:17, 6 October 2008 (view source)Standingve (Talk | contribs)← Older edit
*USGenWeb project. May have maps, name indexes, history or other information for this county. Select the state, then the county. *USGenWeb project. May have maps, name indexes, history or other information for this county. Select the state, then the county. −*[http://www.familysearch.org/eng/library/fhlcatalog/supermainframeset.asp?display=localitydetails&subject=191418&subject_disp=North+Carolina%2C+Watauga&columns=*,0,0 Family History Library Catalog]. +*[http://www.familysearch.org/eng/library/fhlcatalog/supermainframeset.asp?display=localitydetails&subject=191418&subject_disp=North+Carolina%2C+Watauga&columns=*,0,0 Family History Library Catalog]
[[Category:Watauga_County,_North_Carolina]] [[Category:Watauga_County,_North_Carolina]]

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