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Patent US7150967 - Uisng fluorescent label; mercurimethyl dihydropsoralen - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign inAdvanced Patent SearchPatentsMethods and kits for labeling and detecting thiol containing species and nucleic acids using mercurimethyl-dihydropsoralen compounds and derivatives thereof which intercalate nucleic acids and are highly reactive with thiol containing species are provided. Fluorescent reactions products of the mercurimethyl-dihydropsoralen...http://www.google.com/patents/US7150967?utm_source=gb-gplus-sharePatent US7150967 - Uisng fluorescent label; mercurimethyl dihydropsoralenAdvanced Patent SearchPublication numberUS7150967 B2Publication typeGrantApplication numberUS 10/408,170Publication dateDec 19, 2006Filing dateApr 4, 2003Priority dateApr 8, 2002Fee statusPaidAlso published asUS20040018517Publication number10408170, 408170, US 7150967 B2, US 7150967B2, US-B2-7150967, US7150967 B2, US7150967B2InventorsJeffrey D. Laskin, Christine Martey, Ned Heindel, Marilyn Whittemore, Diane HeckOriginal AssigneeUniversity Of Medicine & Dentistry Of New Jersey, Rutgers, The State University, Lehigh University, Buckman Laboratories International, Inc.Export CitationBiBTeX, EndNote, RefManPatent Citations (21), Non-Patent Citations (4), Classifications (17), Legal Events (5) External Links: USPTO, USPTO Assignment, EspacenetUisng fluorescent label; mercurimethyl dihydropsoralen
US 7150967 B2Abstract
Methods and kits for labeling and detecting thiol containing species and nucleic acids using mercurimethyl-dihydropsoralen compounds and derivatives thereof which intercalate nucleic acids and are highly reactive with thiol containing species are provided. Fluorescent reactions products of the mercurimethyl-dihydropsoralen compounds or derivatives thereof attached to a thiol containing species and nucleic acids fluorescently labeled with these reaction products are also provided.
This invention was supported in part by funds from the U.S. government (NIH Grant Nos. ES03647, ES06897 and ES05022) and the U.S. government may therefore have certain rights in the invention.
The present invention relates to compounds useful for fluorescent labeling and detection. In particular, nucleic acid intercalating mercurimethyl-dihydropsoralen compounds and derivatives thereof such as mercurimethyl-angelicin compounds are provided which are highly reactive with thiol containing species. The product of the reaction of the mercurimethyl-dihydropsoralen compounds or derivatives thereof with a thiol containing species is highly fluorescent.
Fluorescent dyes or tags are used in various applications as highly sensitive detection reagents. Fluorescent dyes or tags that preferentially label a selected component of a sample can be used to determine the presence, quantity or location of that selected component. For example, thiol reactive probes such as BODIPY, fluorescein, Oregon Green, tetramethylrhodamine and Texas Red are use routinely to fluorescently label proteins and polypeptides as these probes react readily with the thiol groups, also called mercaptans or sulfhydryls, present in cysteine residues. Additional examples of thiol reactive probes are set forth in Chapter 2 of the commercial catalog for Molecular Probes, Inc. (Richard Haugland, Handbook of Fluorescent Probes and Research Chemicals, 6th Edition 1996 Molecular Probes, Eugene, Oreg., pp. 47�62).
An object of the present invention is to provide mercurimethyl-dihydropsoralen compounds and derivatives thereof which are highly reactive with thiol containing species and produce an intensely fluorescent product upon reaction.
Fluorescent compounds are used widely to detect a variety of proteins and nucleic acids. For example, fluorescent compounds are used routinely in diagnostic assays, DNA sequencing and profiling technologies, genomic analysis, protein identification, antibody binding and metabolite analysis.
Patent CitationsCited PatentFiling datePublication dateApplicantTitleUS4279992Oct 23, 1979Jul 21, 1981Miles Laboratories, Inc.Specific binding assay employing an enzyme-cleavable substrate as labelUS4956480Dec 2, 1986Sep 11, 1990Biocarb Ab7-amino-4-methyl-coumarin-3-carboxyalkyl derivates and fluorescent conjugates thereofUS5188934Nov 14, 1989Feb 23, 1993Applied Biosystems, Inc.Long wavelength, narrow emission bandwidth fluorescent dyes; automatic DNA sequencingUS5248782Dec 18, 1990Sep 28, 1993Molecular Probes, Inc.Long wavelength heteroaryl-substituted dipyrrometheneboron difluoride dyesUS5268486May 15, 1992Dec 7, 1993Carnegie-Mellon UnversityMethod for labeling and detecting materials employing arylsulfonate cyanine dyesUS5274113Nov 1, 1991Dec 28, 1993Molecular Probes, Inc.Long wavelength chemically reactive dipyrrometheneboron difluoride dyes and conjugatesUS5371241Jul 19, 1991Dec 6, 1994Pharmacia P-L Biochemicals Inc.Fluorescein labelled phosphoramiditesUS5433896May 20, 1994Jul 18, 1995Molecular Probes, Inc.Dibenzopyrrometheneboron difluoride dyesUS5437980May 17, 1993Aug 1, 1995Molecular Probes, Inc.Combining phenanthridium dye staining solution with a sample containg living cell, illumination with light source, detecting fluorescent signalUS5442045Mar 8, 1993Aug 15, 1995Molecular Probes, Inc.Biological conjugates of fluorescent rhodol dyesUS5451663Apr 8, 1993Sep 19, 1995Molecular Probes, Inc.Long wavelength chemically reactive dipyrrometheneboron difluoride dyes and conjugatesUS5583236Dec 2, 1994Dec 10, 1996Pharmacia Biotech Inc.Primers for dna sequencingUS5627027 *Sep 22, 1992May 6, 1997Carnegie Mellon UniversityCyanine dyes as labeling reagents for detection of biological and other materials by luminescence methodsUS5654442Mar 8, 1995Aug 5, 1997The Perkin-Elmer Corporation4,7-dichlorofluorescein dyes as molecular probesUS5658735Nov 9, 1995Aug 19, 1997Biometric Imaging, Inc.Cyclized fluorescent nucleic acid intercalating cyanine dyes and nucleic acid detection methodsUS5696157Nov 15, 1996Dec 9, 1997Molecular Probes, Inc.Sulfonated derivatives of 7-aminocoumarinUS5700921 *Nov 27, 1995Dec 23, 1997Vector LaboratoriesReacting nucleic acid with protected pro-thiol aryl azide, deprotecting, reacting with label conjugated to thiol-reactive groupUS6255324Nov 25, 1998Jul 3, 2001Ned D. HeindelAmino-and mercurio-substituted 4′,5'-dihydropsoralens and therapeutical uses thereofUS6291203Dec 3, 1998Sep 18, 2001Molecular Probes, Inc.Unsymmetrical fluorescent dyes for organellesUS6299055Apr 23, 1998Oct 9, 2001Lear Automotive Dearborn, Inc.Manufacturing processes of service boxes and their partsUS6335446Oct 5, 1999Jan 1, 2002Oxford Glycosciences (Uk) Ltd.Quinolinium- and pyridinium-based fluorescent dye compounds* Cited by examinerNon-Patent CitationsReference1Chapter 2 of the commerical catalog for Molecular Probes, Inc. Richard Haugland, Handbook of Fluorescent Probes and Research Chemicals, 6th Edition 1996.2 *Naveenan et al. "Reactive Thiol Grooups in Rat Liver Acid Phosphatase" Enzyme 33, pp. 197-204 1985.3 *Saffran et al. "Site-directed psoralen crosslinking of DNA" Proc. Natl. Acad. Sci. USA, vol. 79, pp. 4594-4598, 1982.4Song et al., "Labeling of Nucleic Acids with Psoralens", Annals New York Acad. Sci. 1980 346:355-367.* Cited by examinerClassifications U.S. Classification435/6.12, 530/350, 435/7.1, 530/300, 435/7.2, 536/26.6, 536/24.3, 536/23.1, 506/4, 435/6.13International ClassificationG01N33/533, C07K17/00, C07H21/00, C12Q1/68, G01N33/53Cooperative ClassificationG01N33/533European ClassificationG01N33/533Legal EventsDateCodeEventDescriptionAug 13, 2014ASAssignmentEffective date: 20130628Free format text: NUNC PRO TUNC ASSIGNMENT;ASSIGNOR:THE UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY;REEL/FRAME:033525/0369Owner name: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, NEW JAug 1, 2014REMIMaintenance fee reminder mailedMay 19, 2010FPAYFee paymentYear of fee payment: 4Apr 28, 2008ASAssignmentOwner name: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OFFree format text: CONFIRMATORY LICENSE;ASSIGNOR:UNIVERSITY OF MED/DENT NJ NEWARK;REEL/FRAME:020867/0414Effective date: 20030701Oct 29, 2003ASAssignmentOwner name: BUCKMAN LABORATORIES INTERNATIONAL, INC., TENNESSEFree format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:WHITTEMORE, MARILYN;REEL/FRAME:014630/0721Effective date: 20030730Owner name: LEHIGH UNIVERSITY, PENNSYLVANIAFree format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:HEINDEL, NED;MARTEY, CHRISTINE;REEL/FRAME:014630/0757Effective date: 20030728Owner name: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, NEW JFree format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:HECK, DIANE;REEL/FRAME:014630/0743Effective date: 20031020Owner name: UNIVERSITY OF MEDICINE AND DENISTRY OF NEW JERSEY,Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:LASKIN, JEFFREY D.;REEL/FRAME:014630/0696Effective date: 20031020RotateOriginal ImageGoogle Home - Sitemap - USPTO Bulk Downloads - Privacy Policy - Terms of Service - About Google Patents - Send FeedbackData provided by IFI CLAIMS Patent Services

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Oval Mozambique Loupe Clean Loose Gemstones | eBay
Oval Mozambique Loupe Clean Loose Gemstones
Gemstone : Natural Ruby Color : Lively Pinkish Red. Weight: 1.25 Carats Hardness: 9(Mohs Scale). Stone ID : A12051 Clarity: VS2, Near Loupe Clean. Pcs: 1 Origin: Niassa Mines (Mozambique). Clarity Scale.
Gemstone : Natural Ruby Color : Lively Pigeon Blood Red. Weight: 2.51 Carats Hardness: 9 (Mohs Scale). Stone ID : R12381 Clarity: VVS2, Loupe-Clean. Clarity Scale. VVS: Very, Very Slight Inclusions. Pcs: 1 Origin: Niassa Mines (Mozambique).
Gemstone : Natural Ruby Color : Fiery Rich Pigeon Blood Red. Shape: Oval Remarks: Free GRS & IGI Certificate (See Below). Weight: 2.03 Carats Hardness: 9(Mohs Scale). Stone ID : R11479 Clarity: VVS2, Loupe-Clean.
Gemstone : Natural Ruby Color : Rich Intense Pigeon Blood Red. Pcs: 1 Origin: Niassa Mines (Mozambique). Shape: Oval Remarks: Free GRS Certificate(See Below). Stone ID : R11938 Clarity: IF, Flawless. IF: Internally Flawless.
Gemstone : Natural Ruby Color : Fiery Vivid Purplish Red. Weight: 2.01 Carats Hardness: 9(Mohs Scale). Stone ID : R11477 Clarity: VVS2, Loupe-Clean. Shape: Oval Remarks : Free GRS Certificate (See Below).
Approx 7.24 Carats in weight, Deep Orange Colour Natural Citrine Loose Gemstone. Gemstone Measuring Approx 12x9mm wide oval faceted cut. The depth cut on this gemstone are deep Cut Bottom. Clarity:Refers to the amount and size of natural imperfections in the gemstone.
19x13mm Oval Deep Orange Natural Citrine Loose Gemstone 18.87 carats VVS Clarity
Beautiful Deep Orange Colour Large Oval Cut 19x13 mm wide Natural Citrine Loose Gemstone. Clarity:Refers to the amount and size of natural imperfections in the gemstone. This may be internal (inclusions) or external (blemishes).
2.30 Ct 100% NATURAL Bio-COLOR-African-TOURMALINE-Oval-Cut-Loose Gemstone>au 505
Eye Clean Mozambique Oval Loose Gemstones

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The 6 Best Hotels near Marrara Sporting Complex, Darwin, Australia - Booking.com
Hotels & places to stay near Marrara Sporting Complex, Darwin (Australia)
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Jingili, Darwin (0.7 miles from Marrara Sporting Complex)
Darwin (0.6 miles from Marrara Sporting Complex)
Davowil. Philippines
Mercure Darwin Airport Resort 4-star hotel This is a Preferred property. It provides excellent service, great value and has brilliant reviews from Booking.com guests. The property may pay Booking.com a bit more to be in this programme.
Description Free airport transfers, free WiFi and free car parking are provided at Mercure Darwin Airport Resort, just 350 metres from Darwin Airport.
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The Leprechaun Resort 3 stars This is a Preferred property. It provides excellent service, great value and has brilliant reviews from Booking.com guests. The property may pay Booking.com a bit more to be in this programme.
Winnellie, Darwin (2.2 miles from Marrara Sporting Complex)
Description Located 5 km from Darwin CBD and 7 km from Darwin Airport, is The Leprechaun Resort. The refurbished resort offers modern air-conditioned rooms with an LCD TV, fridge and tea/coffee-making facilities....
Winnellie, Darwin (1.9 miles from Marrara Sporting Complex)
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"Your facilities are excellent and I feel very comfortable staying at Coconut Grove. Have stayed here many times."
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Party Wear Indian Look Sari Royal Look Traditional Sari Saree X 419 | eBay Please enable JavaScript Our new search experience requires JavaScript to be enabled. Please enable JavaScript on your browser, then try again.
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— Clerc, 1852, from Woodward 1978:336
The largest group of students during the first seven decades of the school were from Martha’s Vineyard, and they brought MVSL with them.[7]:10 There were also 44 students from around Henniker, New Hampshire, and 27 from the Sandy River valley in Maine, each of which had their own village sign language.[7]:11[nb 3] Other students brought knowledge of their own home signs.[7]:11 Laurent Clerc, the first teacher at ASD, taught using French Sign Language (FSL), which itself had developed in the Parisian school for the deaf established in 1755.[6]:7 From this situation of language contact, a new language emerged, now known as ASL.[6]:7
Throughout West Africa, ASL-based sign languages are spoken by educated deaf adults.[17]:410 These languages, imported by boarding schools, are often considered by associations to be the official sign languages of their countries, and are named accordingly, e.g. Nigerian Sign Language, Ghanaian Sign Language.[17]:410 Such signing systems are found in Benin, Burkina Faso, Côte d'Ivoire, Ghana, Liberia, Mauritania, Mali, Nigeria, and Togo.[17]:406 Due to lack of data, it is still an open question how similar these sign languages are to the variety of ASL used in America.[17]:411

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Pink Floyd Back Catalogue Licensed Poster 90cm X 60cm Brand NEW | eBay Skip to main contenteBayShop bycategoryEnter your search keywordAll Categories AdvancedeBay DealsG'day, (Sign in to bid or buy)My eBayExpand My eBaySellExpand SellCommunityExpand CommunityCustomer Support
Details about PINK FLOYD-Back Catalogue-Licensed POSTER-90cm x 60cm-Brand New
PINK FLOYD-Back Catalogue-Licensed POSTER-90cm x 60cm-Brand New
eBay item number:330970668900
13 Dec, 2013 04:12:15 AEDST View all revisions


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Words containing crimesmit | Words that contain crimesmit
Words containing crimesmit | Words that contain crimesmit http://www.thefreedictionary.com/words-containing-crimesmitPrinter Friendly
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Mosiso MacBook Pro 13 Case, Ultra Slim Soft-Touch Plastic See Through Hard Shell Snap On Cover for MacBook Pro 13.3" (A1278 with or without Thunderbolt) Aluminum Unibody with CD-ROM Drive, Gray-1 - Walmart.com
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Electrode, Comp-351927373, DC-prod-dfw6, ENV-prod-a, PROF-PROD, VER-18.4.5-rc-1, SHA-1d465de19fada6e2cc82b85d39c4dfa2e170a853, CID-c8a65aa0-c3f-16a459ecb763da, Generated: Mon, 22 Apr 2019 15:16:35 GMT
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Mosiso MacBook Pro 13 Case, Ultra Slim Soft-Touch Plastic See Through Hard Shell Snap On Cover for MacBook Pro 13.3" (A1278 with or without Thunderbolt) Aluminum Unibody with CD-ROM Drive, Gray-1
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— Macbook Air 11" (A1465 / A1370)
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1. Start with the top cover of the case. Clip the 2 clips at the back of the MacBook first.
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*** Apple MacBook are registered trademarks of Apple, Inc. Products are Apple compatible and not endorsed by Apple, Inc.
13MBR_NR-Gray
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© 2019 Walmart. All Rights Reserved. To ensure we are able to help you as best we can, please include your reference number: RMAUVO5LIM
Electrode, Comp-357073473, DC-prod-dfw5, ENV-prod-a, PROF-PROD, VER-18.4.5-rc-1, SHA-1d465de19fada6e2cc82b85d39c4dfa2e170a853, CID-2f6b97d2-59a-16a459ecb78997, Generated: Mon, 22 Apr 2019 15:16:35 GMT
Electrode, Comp-283796775, DC-prod-dfw5, ENV-prod-a, PROF-PROD, VER-29.0.7-rc-3, SHA-2eb4f85031ba5beca5b3f8f5e6902a74698fd7a6, CID-1b2d9eef-0c9-16a459ecb4ca9d, Generated: Mon, 22 Apr 2019 15:16:35 GMT

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Ethiopian troops patroll at the entrance of an abandoned building in Baidoa, on March 2, 2012. Ethiopian troops who entered Somalia in November 2011 to help fight Al-Qaeda linked Shebab insurgents have begun their withdrawal from the key central city of Baidoa, the foreign ministry said Thursday. (AFP/File)
"Ethiopia's troops are pulling out of Baidoa and AMISOM will be taking over," foreign affairs ministry spokesman Dina Mufti told AFP, referring to the African Union force in Somalia.
Ethiopia has for several months said it plans to hand over control of the city to AMISOM, whose 17,700-strong force is backing Mogadishu's weak central government.
The surprise and unexplained withdrawal from Hudur sparked fears that Ethiopia's pullout would lead to a security void and a possible return of the Shebab.
A contingent of Kenyan troops which entered Somalia in October 2011 has since been integrated into AMISOM, but Ethiopia's forces -- estimated between 3,000 and 8,000 troops -- remained independent, with Addis Ababa footing the bill.

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The importance by Nadezhda Kobzarenko 220 views
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1. The way to success… O. Тiurina, J. Mironova, T. Oglezneva, D. Jurina, A. Patrusheva, M. Ivanova, N. Akulova.
2. Organization: What is the IB mission and legal status? Mission Core values to develop inquiring, Motivated by a mission knowledgeable and Partnerships caring young people Quality who help to create a better and more Participation peaceful world through International mindedness intercultural understanding and respect. Legal status The IB is a non-profit making Swiss Foundation registered in 1968. The activities of the organization are determined by an Act of Foundation approved by the Swiss authorities.Page 2
3. Programmes : What is the Learner Profile? IB learners strive to be: Inquirers Knowledgeable Thinkers Communicators Principled Open-minded Caring Risk-takers Balanced ReflectivePage 3
4. Diploma Ages 16 - 19 Student Professional School Curriculum assessment development evaluationPage 4
5. Students study concurrently:  three subjects at higher level (240 hours each).  three subjects at standard level (150 hours each).  all three parts of the core. The IB Learner Profile and the core are central to the philosophy of the Diploma Programme.Page 5
6. Based on student and teacher interest, course offerings include: GROUP 1 GROUP 2 GROUP 3 HL English A1 SL/HL Language B HL History of Americas (Spanish, French) SL Psychology SL Environmental Systems GROUP 4 GROUP 5 GROUP 6 SL Biology SL Mathematics HL Visual ArtsSL Environmental Systems HL Film
7. The extended essay: limit of 4,000 words investigate a topic of individual interest independent research and writing skills  must include “…techniques appropriate to the discipline”  students select topic and work with volunteer instructors in topic area
8. The interdisciplinary TOK course: designed to provide coherence by:  exploring the nature of knowledge across disciplines  encouraging an appreciation of other cultural perspectivesPart I – focus on limitations of humans as knowers – perceptions, emotions,languages, reasonPart II – development of skills to evaluate knowledge claims in the variousdisciplines.
9. Participation in the school’s CAS program: to be involved in artistic pursuits, sports and community service work awareness and appreciation of life  the hours are designed to be on-going; spanning the duration of the Diploma program
10.  The diploma is graded over 45 Includes both final points giving ample scope to examinations and internal differentiate student ability assessment  Marks awarded for each course All 4,000 examiners are ‘quality range from 1 (lowest) to 7 (highest). checked’  Diploma is awarded to students who The IB undertakes random gain at least 24 points. inspections of schools during exams.  The overall diploma pass rate is broadly consistent year on year Results are published on 5 July for May session and 5 January for the  Diploma Programme assessment – November session. principles and practice – available on www.ibo.org Page 10
11. Individual pieces of work produced as part of a course of study. oral exercises in language subjects projects student portfolios class presentations practical laboratory work mathematical investigations artistic performances
12. Some assessment tasks marked externally by examiners. world literature assignments for language A1 written assignments for language A2 essays for theory of knowledge and extended essays.
13.  Externally marked examinations form the greatest share of the assessment for most subjects. The grading system is criterion-based
14. The IB works closely with universities in all regions of the world togain recognition for the IB diploma: Direct online access for university admissions officers and government officials to syllabuses and recent examination papers A database of university admission policies on www.ibo.org Recognition in over 100 countries Recognition by over 2,000 universities Some universities offer scholarships and advanced placement for IB students Page 14
15.  Universities consider the IB Diploma to be one of the most demanding secondary school curricula, offering ideal preparation for post-secondary studies. A students participation in IB courses is, therefore, a very important consideration in admission decisions. It is to a students distinct advantage to have completed IB courses, but especially so if the student is completing the IB Diploma. - CURT (College & University Task Force), July, 2009
16.  Admissions assumptions: What do universities assume about the IB graduate?  Accepts challenges  Strong academic foundation  Consistency  Excellent research & writing skills  Excellent critical thinking skills  Strong oral presentation skills  Community engagement  Mature & responsible
18.  “Through high quality education we create a better world.”  Idealistic, peace promoting  Culturally aware  Quality, standards  University recognition & challenge  “International and Baccalaureate complementing opposites that make the IB.”Page 18
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Frost & Sullivan: Global Smart Cities market to reach US$1.56 trillion by 2020 Contact Us
dansk	Deutsch	español	Français	italiano	Nederlands	norsk	português	suomeksi	svenska	Frost & Sullivan: Global Smart Cities market to reach US$1.56 trillion by 2020
~Connectivity and the Emergence of Smart Cities at GIL 2014 Australia
Nov 26, 2014, 00:08 ET
from Frost & Sullivan SYDNEY, Nov. 26, 2014 /PRNewswire/ -- The global smart city market will be valued at US$1.565 trillion in 2020. Over 26 Global Cities are expected to be Smart Cities in 2025, with more than 50% of these smart cities from Europe and North America.
There are significant opportunities to raise efficiencies in managing cities to make them smart cities. Mr. Fernandez elaborates, "By 2031, Sydney will have around 1.3 million additional people – that is more than the current population of Adelaide. By 2030, Sydney ports will handle more than one quarter of the national volume of container freight. Sydney and regional NSW will only have enough waste landfill capacity for another 20 years. 24% of the city population take public transport to work but only 20% can get to work in less than an hour. The cost of congestion in Sydney is over A$5.2 billion a year."

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Booking.com: Hotels in Reitani. Book your hotel now!
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San Lorenzo Holiday Opens in new window
Reitani Show on map 800 feet from center
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San Lorenzo Noto Villa Girasole is a self-catering accommodations located in Reitani, 328 feet from the beach. Its garden is equipped with barbecue facilities.
Villa Oasi di Vendicari Opens in new window
Reitani Show on map 1.3 miles from center
Villa Oasi di Vendicari is located in Reitani. This self-catered vacation home has a garden, grill facilities, free WiFi and free private parking.
Arabel Villas Opens in new window
Reitani Show on map 1,000 feet from center
Located in Reitani, Arabel Villas has accommodations with air conditioning and access to a garden with a grill.
Tra Cielo e Mare Opens in new window
Reitani Show on map 0.6 miles from center
Tra Cielo e Mare is located in Reitani and offers a garden, a private beach area and barbecue facilities.
Archiammare Sea Opens in new window
Reitani Show on map 0.7 miles from center
Featuring a swimming pool, a garden and barbecue facilities and views of the pool, Archiammare Sea is located in Reitani and has accommodations with free WiFi.
Florí Casa Vacanze Opens in new window
Reitani Show on map 1,500 feet from center
Located in Reitani in the Sicilia region, Florí Casa Vacanze provides accommodations with free WiFi and free private parking.
Boatapartment Opens in new window
Reitani Show on map 2,800 feet from center
Boatapartment is located in Reitani and offers free bikes, a shared lounge and a garden. This vacation home provides air-conditioned accommodations with a terrace.
Appartamenti San Lorenzo Marzamemi Cecilia Opens in new window
Reitani Show on map 150 feet from center
Featuring an outdoor pool and garden views, Appartamenti San Lorenzo Marzamemi Cecilia is located in Reitani.
Villa Rossella Vendicari Opens in new window
Located in Reitani, 23 mi from Siracusa, Villa Rossella Vendicari offers 2 houses, each with its private garden area. The holiday homes have a flat-screen TV, air conditioning and a kitchenette.
Villa Verdemare Opens in new window
Offering a garden and terrace, Villa Verdemare is set in Reitani, 984 feet from San Lorenzo beach and a 20-minute drive from Noto. All units are air conditioned and feature a seating and dining area.
San Lorenzo - Timo Opens in new window
Reitani Show on map 1,150 feet from center
With a seafront location in Reitani, San Lorenzo - Timo offers accommodations with a private pool and private parking. Free WiFi is available throughout the property.
Appartamento a 40 metri dal mare di Sanlorenzo Opens in new window
Reitani Show on map 350 feet from center
Appartamento a 40 metri dal mare di Sanlorenzo is located in Reitani. Located on the beachfront, this property has a restaurant, a garden and barbecue facilities.
Mansardina a San Lorenzo Opens in new window
Featuring air-conditioned accommodations with a terrace, Mansardina a San Lorenzo is located in Reitani. This beachfront property has a balcony and free private parking.
Casa vacanza del mare Opens in new window
Reitani Show on map 1,950 feet from center
Located in Reitani, Casa vacanza del mare offers a shared lounge, a garden and a grill. This vacation home has free private parking and a shared kitchen.
82 properties found in Reitani
959130|2,964120,933650,957290,934870,946580|5,956580,959130|1,929420,929430,944370|1,961300|1,959130,955070,964660|5,957680,883310,944370|5,955550,961090,883310|4,950390,964660|2,758330,956580|1,835220,959920,960040|1,960040,960290,950710,964660|1,957240,964660|4,962070,964660,927930|1,946580|3,960250


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Victory for parents who battled taxman's nightmare child benefit rules | Daily Mail Online
Essex couple put the 'wrong' parent's name down on child benefit forms
Raina and Martin were initially refused the right to transfer valuable state pension qualifying years between them
Couples who try to transfer tell us they have faced frustrating battle with HMRC
Time limit rules mean parents cannot transfer credits for 2010/11 to 2016/17
HMRC apparently relented on time limits in this case
It says it will allow transfers outside the window 'in reasonable circumstances'
It's therefore still unclear if Raina and Martin's victory will benefit other parents
Comes as This is Money launched campaign last week about the fiasco
Published: 05:47 EST, 2 October 2018 | Updated: 09:53 EST, 3 October 2018
A delighted mum and dad have won 10 years' worth of state pension credits after spending months fighting the taxman's baffling red tape.
Raina Thurgood and Martin Ryott were finally allowed to correct an innocent but common error made when applying for child benefit - putting the 'wrong' parent's name down on the form.
The Essex couple will potentially be tens of thousands of pounds better off in retirement, but it's unclear if their victory will benefit other parents.
This is Money launched a campaign last week against the unfairness of parents getting smaller state pensions because they made simple errors on child benefit forms - including full backdating of credits for those who don't realise they need to fill them in.
Child benefit: Parents face smaller state pensions in old age because they made simple error over forms
Raina and Martin, who were originally refused the right to transfer valuable state pension qualifying years from her to him, hailed it as 'fantastic news'.
It follows our call last week for HMRC to fix the current shambles, where the taxman has given them and other couples incorrect information and failed to explain its refusal of appeals to sort things out.
CHILD BENEFIT STATE PENSION CAMPAIGN
TANYA JEFFERIES: An innocent paperwork blunder after giving... Thousands of mums and dads are losing state pension ¿...
It's important a parent who is not working is the one named on the form to get child benefit, as credits are worthless to someone employed and already paying enough National Insurance to get a full state pension.
You can correct this via a transfer of state pension credits between a couple.
But the option to do this is so obscure even former Pensions Minister Steve Webb wasn't aware of it until he tried to help a This is Money reader in June.
Webb, now policy director at Royal London, said: 'It is great news that, with the help of This is Money, Mr Ryott has now been able to significantly improve his pension record by getting the right National Insurance credits.
How much extra state pension could Martin get in retirement?
Raina's transfer of her unneeded state pension credits to Martin could mean a substantial boost to his state pension - especially if he is more than 10 years short of the 35 qualifying years of NI needed for a full state pension, which is currently £164.35 a week.
Each credit (or year of HRP) is worth 1/35 of the value of the state pension – around £244 per year or £4,880 over the course of a typical 20 year retirement.
Ten years of credits gained works out at £48,800, if Martin lives for a couple of decades after reaching state pension age.
'But it cannot be right that the system is so complex that it takes extensive correspondence and chasing and battling with obscure regulations simply to get what should have been rightfully theirs in the first place.
'This whole system needs reviewing to make sure that it works as it was originally intended.'
Treasury committee chair, Nicky Morgan MP, last week called on the Government to do more to inform parents who are missing out on credits about the transfer option.
She wrote to Work and Pensions Secretary Esther McVey, saying: 'I believe the DWP could do more to inform parents with low or no income that they can protect their entitlement to state pension by transferring National Insurance credits from a spouse, partner or civil partner who claims child benefit.
'The information to such parents should make it clear that they can do this online or by post using HMRC form CF411A.
'I would welcome your views on how awareness could be raised.'
This is Money asked HMRC why it has done a U-turn in Raina and Martin's case on time limit rules which mean parents cannot apply to transfer credits for the tax years 2010/11 until 2016/17.
It said: 'Parents should apply for transfers of NI credits before the end of the following tax year.
'Where a customer makes an application outside this window, HMRC can accept it in reasonable circumstances.' Read more about the transfer rules below.
What are the rules on credit transfers?
We asked HMRC whether its decision in Raina and Martin's case will be applied to all parents who try to make transfers.
There is no time limit on transfer applications before 2010, but there is meant to be from 2010/11 to 2016/17.
HMRC said: 'Parents should apply for transfers of NI credits before the end of the following tax year.
'Where a customer makes an application outside this window, HMRC can accept it in reasonable circumstances.'
What else does it say you should know?
· Customers should apply before the end of the following tax year to ensure they can successfully transfer NI credits.
· HMRC cannot transfer credits which are awarded to a customer after a transfer claim has been made without the customer making a further application.
· Transfers of NI credits cannot be accurately processed until the child benefit claimant’s National Insurance record for the previous tax year has been fully updated, usually around October.
· HMRC advise that to avoid having to claim to transfer NI credits each year, the child benefit claim should be transferred to the non-working partner.
· If parents wish to change the child benefit claimant to the non-working partner they should contact HMRC on 0300 200 3100.
Credits can be transferred for the most recent tax year, if you claim before 5 April in the following tax year, by filling in form CF411A.
How did Essex couple win battle?
Couples who try to transfer credits tell us they have faced a long and frustrating battle with HMRC.
Raina and Martin have been trying for months to sort out their records.
When they initially applied for child benefit, both were working and Raina made the claim.
Martin, 50, a production editor who stopped working in 2008 to look after the couple's three children, didn't realise at the time he should start claiming instead or it would affect his state pension.
He therefore lost state pension credits and HRP - the forerunner to credits, known as Home Responsibilities Protection - for 10 years in total.
Martin tried to transfer of two years of HRP from 2008 to 2010 from Raina's name into his one, as he assumed time limits on transfers following 2010 meant he had no chance of getting the later ones.
But HMRC sent him a confusing rejection letter, stating that claimants had to reach state pension age between April 2008 and April 2010 to qualify for transfers.
It later admitted this was incorrect and apologised.
HMRC confirmed the condition is you must reach state pension age on or after 6 April 2008, and that the bungle would be sorted in future decision letters.
But it failed to explain whether earlier rejections would be reversed, and if not why it was standing firm on them.
Raina and Martin were then left in limbo, after HMRC ignored their letter challenging the refusal of their transfer in the early summer.
It also failed to respond to This is Money's repeated interventions on their behalf, right up until last week.
The couple were therefore overjoyed to receive HMRC's letter, saying they could transfer all 10 years of credits and HRP between them.
'If you are entitled to credits you should get them, without having to deal with stupid letters from HMRC about it,' said Raina, 48, a senior customer services manager.
'Hopefully other parents who have missed out will receive similar news.'
Raina added that she hoped 'a clearer and more straightforward process for all parents to transfer NI credits will come about in future'.
The two-tier state system has changed for people retiring since 6 April 2016, when it was replaced by a new 'flat rate' state pension.
This is currently worth £164.35 a week.
Victory for parents who battled taxman's nightmare child benefit rules

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