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See all 403 Hotels in Canton of Bern Hotel Savoy Bern Hotel Savoy Bern Neuengasse 26, Bern 3011 4.0 out of 5.04.6 out of 5 (41 reviews) Situated in Bern, this hotel is within a 5-minute walk of French Church, Bundeshaus, and Bern Art Museum. Clock Tower and … $147Hotel Schweizerhof Bern & THE SPA Hotel Schweizerhof Bern & THE SPA Bahnhofplatz 11, Bern 3001 5.0 out of 5.04.8 out of 5 (219 reviews) Located in the heart of Bern, this luxury hotel is within a 10-minute walk of Bern Art Museum, Bundeshaus, and Clock Tower. … $386Best Western Hotelbern Best Western Hotelbern Zeughausgasse 9, Bern 3011 4.0 out of 5.04 out of 5 (428 reviews) Located in the heart of Bern, this hotel is steps from French Church and Clock Tower. Bundeshaus and Bern Art Museum are also … $149Hotel Allegro Bern Hotel Allegro Bern Kornhausstrasse 3, Bern 3000 4.5 out of 5.04.2 out of 5 (247 reviews) Located in the heart of Bern, this luxury hotel is within a 10-minute walk of Botanical Garden and Clock Tower. Bundeshaus an … $169Hotel Alpenblick Hotel Alpenblick Kasernenstrasse 29, Bern 3013 3.0 out of 5.04.3 out of 5 (443 reviews) Situated in Bern, this hotel is within 1 mi (2 km) of Bern Rose Garden, Bundeshaus, and Stade de Suisse Wankdorf. Clock Tower … $158Gasthaus Steinbock Gasthaus Steinbock Gsteig 6, Wilderswil, Gsteigwiler 3814 2.0 out of 5.04.3 out of 5 (31 reviews) Situated in Gsteigwiler, this hotel is within 1 mi (2 km) of Skydive Interlaken and Tell-Spiele. Seilpark Interlaken and … $119Hotel Waldhorn Hotel Waldhorn Waldhöheweg 2, Bern 3013 3.0 out of 5.04.4 out of 5 (52 reviews) Situated in Bern, this hotel is within 1 mi (2 km) of Botanical Garden, Bundeshaus, and Clock Tower. Bern Art Museum and … $134Hotel Kreuz Bern Hotel Kreuz Bern Zeughausgasse 41, Bern 3011 3.0 out of 5.03.7 out of 5 (376 reviews) Located in the heart of Bern, this hotel is within a 5-minute walk of French Church, Bundeshaus, and Bern Art Museum. Clock … $156Hotel Bellevue Palace Hotel Bellevue Palace Kochergasse 3-5, Bern CH-3000 5.0 out of 5.04.8 out of 5 (227 reviews) This family-friendly Bern hotel is located on a river, just steps from Clock Tower and Bundeshaus. Berner Munster and Bern … Get Rates Hotel Metropole Hotel Metropole Zeughausgasse 26, Bern 3011 3.0 out of 5.03.4 out of 5 (450 reviews) Located in the heart of Bern, this hotel is within a 5-minute walk of French Church, Bundeshaus, and Bern Art Museum. Clock … $143
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Good hotel close to amenities 5 out of 5 Standard room has no windows and lighting is not adequate for purpose. Bad smell from drains. Other than that very expensive but good A verified traveler stayed at Hotel Allegro Bern Posted 3 days ago Reviews for Hotel Allegro Bern Expedia Verified Review 5 out of 5 Great staff! Would recommend I don't know what else to tell you, but this review is making write more so here I am writing more. A verified traveler stayed at Hotel Savoy Bern Posted 4 days ago Reviews for Hotel Savoy Bern
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Monday, December 17 - History Channel's "The Great Ships: The Pirate Ships" : Dailydocumentariesjump to contentmy subredditsannouncementsArtAskRedditaskscienceawwblogbookscreepydataisbeautifulDIYDocumentariesEarthPornexplainlikeimfivefoodfunnyFuturologygadgetsgamingGetMotivatedgifshistoryIAmAInternetIsBeautifulJokesLifeProTipslistentothismildlyinterestingmoviesMusicnewsnosleepnottheonionOldSchoolCoolpersonalfinancephilosophyphotoshopbattlespicsscienceShowerthoughtsspacesportstelevisiontifutodayilearnedTwoXChromosomesUpliftingNewsvideosworldnewsWritingPromptsedit subscriptionsfront-all-random | AskReddit-funny-news-todayilearned-worldnews-pics-gifs-gaming-videos-aww-Showerthoughts-movies-mildlyinteresting-nottheonion-Jokes-science-television-OldSchoolCool-space-creepy-sports-explainlikeimfive-tifu-Futurology-IAmA-LifeProTips-TwoXChromosomes-books-photoshopbattles-EarthPorn-food-WritingPrompts-UpliftingNews-personalfinance-dataisbeautiful-Music-nosleep-Art-DIY-askscience-GetMotivated-Documentaries-history-gadgets-InternetIsBeautiful-listentothis-philosophy-announcements-blogmore »reddit.com DailydocumentariescommentsWant to join? Log in or sign up in seconds.|Englishlimit my search to /r/Dailydocumentariesuse the following search parameters to narrow your results:subreddit:subredditfind submissions in "subreddit"author:usernamefind submissions by "username"site:example.comfind submissions from "example.com"url:textsearch for "text" in urlselftext:textsearch for "text" in self post contentsself:yes (or self:no)include (or exclude) self postsnsfw:yes (or nsfw:no)include (or exclude) results marked as NSFWe.g. subreddit:aww site:imgur.com dogsee the search faq for details.advanced search: by author, subreddit...this post was submitted on 17 Dec 20124 points (75% upvoted)shortlink: remember mereset passwordloginSubmit a new linkSubmit a new text postDailydocumentariessubscribeunsubscribe270 readers~1 user here nowAfter watching a documentary, I always want to discuss it with someone -- see what they found most interesting and how accurate they found it. This subreddit was set up with the intention of watching one documentary/episode of a documentary each week. A discussion thread will be posted with the title of a documentary and a link to the documentary on Netflix. This thread will be for discussion of the day's documentary. People may post in the thread throughout the day as they watch it, posing questions or responding to other's thoughts or questions. You don't have to participate every single day - just whenever you have the time! Also, feel free to comment on past threads with answers or thoughts. Let's all expand our base of knowledge together!
created by Dkap322a community for 3 yearsmessage the moderatorsMODERATORSDkap322about moderation team »discussions in /r/Dailydocumentaries<>X1 points · 1 comment Your Place or Minecraft? (2016) - "Game Scholars Being Interviewed about Their Views on Minecraft and The Issues (Social, Political, Gender, Ethics) They face within a Uniquely Made Server." New Web Documentary !!1 points Synchronicities1 points Kolkata, with Sue Perkins (BBC Documentary, 2015)2 points Out Of The Blue - Documentary On Ufos1 points Forced Perspective - Derek Hess Documentary Trailer 11 points Why not give revitalization a shot? Doc. of the Week - Mitt4 points · 1 comment Any possible attempts to revitalize this subreddit?3 points Doc. of the Week - "The Bombing of Germany: American Experience" [Sorry I'm late]4 points Doc. of the Week - "Modern Marvels: The Manhattan Project"6 points Doc. of the Week: "Diamonds of War: Africa's Blood DiamondsThis is an archived post. You won't be able to vote or comment.
345Monday, December 17 - History Channel's "The Great Ships: The Pirate Ships" (movies.netflix.com)submitted 3 years ago by Dkap322commentshareloading...no comments (yet)sorted by: besttopnewcontroversialoldrandomq&alive (beta)there doesn't seem to be anything herePosts are automatically archived after 6 months.Got Itaboutblogaboutsource codeadvertisejobshelpsite rulesFAQwikireddiquettetransparencycontact usapps & toolsReddit for iPhoneReddit for Androidmobile websitebuttons<3reddit goldredditgiftsUse of this site constitutes acceptance of our User Agreement and Privacy Policy (updated). © 2016 reddit inc. All rights reserved.REDDIT and the ALIEN Logo are registered trademarks of reddit inc.create a new accountusername:password:verify password:email: (optional)remember meget the best of reddit emailed to you once a week. learn moresign uplog inusername:password:remember mereset passwordlog inBy signing up, you agree to our Terms and that you have read our Privacy Policy and Content Policy.English [en]العربية [ar]Беларуская мова [be]български език [bg]Bosanski [bs]català [ca]česky [cs]dansk [da]Deutsch [de]Ελληνικά [el]English (Australia) [en-au]English (Canadian) [en-ca]English (Great Britain) [en-gb]English [en-us]Esperanto [eo]español [es]español [es-ar]eesti keel [et]Euskara [eu]فارسی [fa]suomi [fi]français [fr]Gàidhlig [gd]עברית [he]मानक हिन्दी [hi]hrvatski [hr]Magyar [hu]Հայերեն լեզու [hy]Bahasa Indonesia [id]íslenska [is]italiano (Italy) [it]日本語 [ja]ಕನ್ನಡ [kn_IN]한국어 [ko]Latin [la]1337 [leet]LOL [lol]lietuvių kalba [lt]latviešu valoda [lv]Nederlands [nl]Nynorsk [nn]Norsk [no]Arrrrrrrr! [pir]polski [pl]português [pt] (*)português [pt-pt]português brasileiro [pt_BR]română [ro]русский [ru]slovenčina [sk]slovenščina [sl]српски језик [sr]Srpski [sr-la]Svenska [sv]தமிழ் [ta]ภาษาไทย [th]Türkçe [tr]українська мова [uk]Tiếng Việt [vi]中文 [zh] (*) incomplete volunteer to translateπ Rendered by PID 20530 on app-557 at 2016-09-30 02:42:00.528835+00:00 running 9b22fbe country code: US.

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Patent US5767275 - Preparation of triazolone compounds - Google PatentsSearch Images Maps Play YouTube News Gmail Drive More »Sign inPatentsPreparation of a 1,2,4-triazol-3-one compound substituted in positions 4 and 5 by an alkyl or aryl group and, optionally, in position 2 by an alkyl group, by reacting an ester a of carbamic acid N-substituted by an alkyl or aryl group with a hydrazide of an aliphatic or aromatic carboxylic acid, optionally...http://www.google.com/patents/US5767275?utm_source=gb-gplus-sharePatent US5767275 - Preparation of triazolone compoundsAdvanced Patent SearchTry the new Google Patents, with machine-classified Google Scholar results, and Japanese and South Korean patents.Publication numberUS5767275 APublication typeGrantApplication numberUS 08/424,477PCT numberPCT/EP1993/003119Publication dateJun 16, 1998Filing dateNov 6, 1993Priority dateNov 13, 1992Fee statusPaidAlso published asDE69317122D1, DE69317122T2, EP0668857A1, EP0668857B1, WO1994011357A1Publication number08424477, 424477, PCT/1993/3119, PCT/EP/1993/003119, PCT/EP/1993/03119, PCT/EP/93/003119, PCT/EP/93/03119, PCT/EP1993/003119, PCT/EP1993/03119, PCT/EP1993003119, PCT/EP199303119, PCT/EP93/003119, PCT/EP93/03119, PCT/EP93003119, PCT/EP9303119, US 5767275 A, US 5767275A, US-A-5767275, US5767275 A, US5767275AInventorsAlberto Nigro, Mauro TomaselliOriginal AssigneeAziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A.Export CitationBiBTeX, EndNote, RefManPatent Citations (5), Non-Patent Citations (12), Referenced by (4), Classifications (6), Legal Events (4) External Links: USPTO, USPTO Assignment, EspacenetPreparation of triazolone compounds
US 5767275 AAbstract
Preparation of a 1,2,4-triazol-3-one compound substituted in positions 4 and 5 by an alkyl or aryl group and, optionally, in position 2 by an alkyl group, by reacting an ester a of carbamic acid N-substituted by an alkyl or aryl group with a hydrazide of an aliphatic or aromatic carboxylic acid, optionally N-substituted by an alkyl group, in the presence of a strong base.
1. A process for preparing a 1,2,4-triazol-3-one compound of the formula: ##STR5## where R, R' and R" are defined below, comprising reacting in the presence of a strong base:(a) an ester of an N-substituted carbamic acid of the formula: R'--NH--COOY                                               (X) whereinR' is phenyl, halophenyl or C1 -C10 alkyl optionally substituted by phenyl or phenoxy; and Y is C1 -C5 alkyl; and (b) a hydrazide of an aliphatic or aromatic carboxylic acid of the formula: R"NH--NH--CO--R                                            (XI) whereinR is phenyl or C1 -C10 alkyl optionally substituted by a phenyl group; and R" is hydrogen, C1 -C10 alkyl or 4-(halophenyl)-1-piperazinyl-propyl. 2. The process of claim 1, wherein said strong base is an alkali metal hydroxide, an alkali metal alcoholate, sodium hydride, sodium amide or a mixture thereof.
3. The process of claim 2, wherein said alkali metal is sodium or potassium.
4. The process of claim 1, wherein said reacting step is conducted at a temperature of -40° C. to 200° C. in the further presence of a diluent.
5. The process of claim 1, wherein said reacting step is conducted in the further presence of a diluent;said strong base is sodium hydride, sodium hydroxide, potassium hydroxide, sodium alcoholate, potassium alcoholate or a mixture thereof; and said diluent is immiscible or very poorly miscible with water at the boiling temperature. 6. The process of claim 5, wherein said diluent is methylcyclohexane, toluene, xylene or a mixture thereof.
7. The process of claim 1, wherein said reacting step is conducted in the further presence of a diluent;said strong base is sodium amide; and said diluent is liquid ammonia. 8. The process of claim 1, wherein R' is phenyl, chlorophenyl, methyl, ethyl or phenoxyethyl.
9. The process of claim 1, wherein R" is hydrogen or 4-(halophenyl)-1-piperazinyl-propyl.
10. The process of claim 1, wherein R is phenyl, methyl, ethyl, propyl, isopropyl, hexyl or benzyl.
11. The process of claim 4, wherein said strong base is sodium hydride, sodium hydroxide, potassium hydroxide, sodium alcoholate, potassium alcoholate, or a mixture thereof; andsaid diluent is immiscible or very poorly miscible with water at said temperature. 12. The process of claim 4, wherein said strong base is sodium amide and said diluent is liquid ammonia.
This is 371 of application of PCT/EP93/03119 filed Nov. 6, 1993.
This invention relates to a process for the preparation of triazoles.
More particularly, it relates to a process for the preparation of a 1,2,4-triazol-3-one compound substituted in the positions 4 and 5 by an alkyl or aryl group and optionally substituted in the position 2 by an alkyl group.
1,2,4-triazol-3-ones compounds bi-substituted in positions 4 and 5 or tri-substituted in positions 2, 4 and 5 are useful in themselves or as intermediates. Examples of the said compounds useful for human or animal therapy are described by U.S. Pat. No, 3,857,845 and U.S. Pat. No. 4,338,317.
Typical examples are ethoperidone and nefazodone.
The preparation of these compounds, however, implies a number of drawbacks.
U.S. Pat. No. 4,338,317 teaches to preparare the compounds of the formula: ##STR1## where R is ethyl, R' is hydrogen or phenoxyethyl, and R" is 4-(halophenyl)-1-piperazinyl-propyl, by reacting an N-ethoxy-carboxyethiopropionamide of the formula: ##STR2## where R and R' have the meanings set forth above, with a hydrazine compound of the formula:
H2 N--NH--R"                                          (III)
where R" has the meanings set forth above.
However, this process presents a drawback in that during the reaction of compound (II) with compound (III) a highly toxic gas, i.e. hydrogen sulfide, is produced.
In addition, although the above-mentioned document states that the 1,2,4-triazol-3-one compounds tri-substituted in positions 2, 4 and 5 can be prepared directly from the compounds (II) wherein R' is not hydrogen, it does not disclose any examples of the preparation thereof.
In a subsequent document, G. D. Madding et al. (J. Het. Chem. 22, 1121-26, 1985) state that the said procedure is suitable only for preparing the intermediate compound bi-substituted in positions 2 and 5, from which the desired tri-substituted compound is then prepared by alkylation. Moreover, even though these Authors don't refer specifically to the production of hydrogen sulfide, they recognize the existence of "factors" which prompt to search for other synthesis pathways.
Then, G. D. Madding et al. (loc. cit.) describe two other routes for preparing bi-substituted intermediates from which the desired tri-substituted compound is prepared by alkylation.
The first route involves the cyclization in an alkaline medium of a semicarbazide of the formula:
R'--NH--CO--NH--NH--CO--R                                  (IV)
where R' is phenoxyethyl and R is ethyl.
In turn the semicarbazide compound (IV) is obtained from an isocyanate compound of the formula:
R'--N═CO                                               (V)
where R' has the meanings set forth in connection with formula (IV),
and a hydrazide compound of the formula:
H2 N--NH--CO--R                                       (VI)
where R has the meanings set forth in connection with formula (IV).
Hence, this synthesis has the drawback of using isocyanate compounds which are dangerous and toxic, particularly when they have a low molecular weight and are volatile.
On the other hand, through this pathway H. Gehlen et al. (Ann. 675, 180-188, 1964) had already prepared several compounds of formula I, in which the position 4 is substituted by an alkyl or aryl group and position 5 is substituted by an alkyl group.
However, to prepare the compounds which are tri-substituted in positions 2, 4 and 5, H. Gehlen et al. had to employ another method and the only substituent in position 2 was the phenyl group. Therefore, the tri-substituted compounds prepared by these Authors differ from the compounds which are intended to be prepared according to this invention.
The second route described by G. D. Madding et al. involves the cyclization in a basic medium of an N-carbomethoxyamidrazone compound of the formula: ##STR3## where R' is phenoxyethyl.
In turn, compound (VII) is prepared by reacting a compound of the formula: ##STR4## where R' is phenoxyethyl, with methyl carbazate and the compound of formula (VIII) is obtained by treating an amide of the formula:
R'--NH--CO--C2 H5                                (IX)
where R' is phenoxyethyl, with phosgene.
Therefore, even in this case, a dangerous and toxic gas has to be employed.
Notwithstanding this drawback, the Authors regard this method as the most suitable for large-scale production.
The fact that such a complex process, which does not directly produce the desired tri-substituted compound and involves the use of a dangerous and toxic gas such as phosgene, is considered to be the best one among the methods investigated by the Authors points out the difficulties that the a person skilled in the art must face in the preparation of a compound of formula (I) where R and R' are alkyl or aryl and R" is hydrogen or alkyl.
Therefore, it is still needed a process suitable for directly yielding tri-substituted compounds without involving the use and/or the concurrent production of toxic and dangerous substances.
Surprisingly, it has now be found that this aim may be achieved by condensing a suitable ester of an N-substituted carbamic acid with an optionally N-substituted hydrazide of a carboxylic acid, in the presence of a strong base.
Therefore, it is an object of this invention to provide a process for preparing a 1,2,4-triazol-3-one compound substituted in positions 4 and 5 by an alkyl or aryl group and, optionally, in position 2 by an alkyl group, characterized in that an ester a of carbamic acid N-substituted by an alkyl or aryl group is reacted with a hydrazide of an aliphatic or aromatic carboxylic acid optionally N-substituted by an alkyl group, in the presence of a strong base.
Examples of suitable strong bases are the hydroxides and alcoholates of alkali metals and mixtures thereof, sodium hydride and sodium amide. Preferably, the alkali metal is sodium or potassium.
The reaction is preferably performed under conditions which allow to remove the water and alcohol as they form during the reaction. Examples of suitable conditions are, for example, the use of dehydrating agents and the heating to a temperature at which the volatile substances evaporate.
The reaction temperature is selected so as to prevent significant degradation of the reactants but at the same time complete the reaction quickly to reduce production times to an economic minimum. One of the most widely known and effective techniques to maintain both factors under control lies in the addition of a suitable diluent.
Therefore, the process of this invention is preferably carried out in the presence of a diluent and at a temperature of from -40° C. to 200° C.
When the strong base is sodium hydride, an alkali metal hydroxide, an alkali metal alcoholate or a mixture thereof, the diluent is preferably selected from those which are immiscible or very poorly miscible with water at their boiling temperature so that the water and alcohol which form during the reaction are removed as an azeotrope.
Examples of particularly suitable diluents for this step are aliphatic cyclic hydrocarbons such as methylcyclohexane and aromatic hydrocarbons such as toluene and xylene.
However, when the strong base is sodium amide, the reaction is preferably performed in the presence of liquid ammonia.
The process of this invention is preferably carried out by reacting, under the above-mentioned conditions, 1 mole of a carbamic acid ester of the formula:
R'--NH--COOY                                               (X)
where R' is alkyl or aryl, and
Y is C1 -c5 alkyl,
with from 0.5 to 3 moles of a carboxylic acid hydrazide of the formula:
R"--NH--NH--CO--R                                          (XI)
where R" is hydrogen or alkyl, and
to yield a 1,2,4-triazol-3-one compound (I) where R, R' , R" have the meanings set forth above in connection with the compounds of formula (X) and (XI). As already mentioned, the reaction produces water and an alcohol of the formula YOH, where Y has the meaning set forth above connection with the compound of formula (X).
Preferred meanings of R, R' and R" according to this invention are as follows:
R is phenyl and C1 -C10 alkyl optionally substituted by a phenyl group,
R' is phenyl, halophenyl and C1 -C10 alkyl optionally substituted by phenyl or phenoxy,
R" is hydrogen and C1 -C10 alkyl optionally substituted by an heterocyclic group.
Typical examples of R are phenyl, methyl, ethyl, propyl, isopropyl, hexyl and benzyl.
Typical examples of R' are phenyl, chlorophenyl, methyl, ethyl and phenoxyethyl.
Typical examples of R" are hydrogen and 4-(halophenyl)-1- piperazinyl-propyl.
The following examples are intended to illustrate the present invention without, however, limiting it in any way.
2 3 4-(3-chlorophenyl)-1-piperazinyl!propyl!-5-ethyl-4-(2-phenoxyethyl)-1,2,4-triazol-3-one (nefazodone) hydrochloride.
(Formula I: R=ethyl; R'=phenoxyethyl; R"=3 4(3-chloro-phenyl)-1-piperazinyl!propyl)
N-3 4-(3-chlorophenyl)-1-piperazinyl!-propyl-N'-propionyl-hydrazine (32.5 g; 0.1 moles) (prepared by reacting ethyl propionate with the N-3 4-(3-chlorophenyl)-1-piperazinyl!-propyl-hydrazine (U.S. Pat. No. 4,338,317 ) was dissolved in a solution of potassium hydroxide (6.6 g) in ethyl alcohol (40 ml). The solvent was removed by evaporation under reduced pressure.
To the thus obtained residue ethyl N-(2-phenoxyethyl)-carbamate, prepared as described in U.S. Pat. No. 3,320,302, (20.9 g; 0.1 moles) and xylene (50 ml) were added at 50° C. The reaction mixture was quickly heated under vigorous stirring to 135°-140° C. and maintained at this temperature for 4 hours while removing the distillate.
Water (100 ml) was added and then 37% hydrochloric acid up to pH 4. A heavy oil was formed which was recovered and taken up in isoamyl alcohol (100 ml).
The thus obtained solid product was recrystallised from 95% ethyl alcohol; m.p. 176°-177° C.
2 3 4-(3-chlorophenyl)-1-piperazinyl!propyl!-4,5-diethyl-1,2,4-triazol-3-one (ethoperidone) hydrochloride
(Formula I: R=R'=ethyl; R"=3 4-(3-chlorophenyl)-1- piperazinyl!propyl).
The desired product was prepared following the same method as described in Example 1, except that the ethyl N-(2- phenoxyethyl)-carbamate (20.9 g; 0.1 moles) was substituted for N-ethyl-carbamate (17.6 g; 0.1 moles).
The thus obtained product melts at 201.5° C. (isopropanol).
5-ethyl-4-(2-phenoxyethyl)-1,2,4-triazol-3-one
(Formula I: R'=PhOC2 H4, R=C2 H5, R"=H)
Propionyl hydrazine (53 g; 0.6 moles) was dissolved in a solution of potassium hydroxide (40 g) in ethyl alcohol (120 ml). The solvent was removed by evaporation under reduced pressure.
To the thus obtained residue ethyl N-(2-phenoxyethyl)-carbamate (105 g; 0.5 moles) and xylene (250 ml) were added at 50° C. The reaction mixture was quickly heated under vigorous stirring to 135° C. and maintained at this temperature for 4 hours while removing the distillate.
Xylene was completely removed by evaporation under reduced pressure. The residue obtained was taken up with water (250 ml) and the mixture heated to 80° C. and made acid with 37% hydrochloric acid up to pH 4. A solid was formed, which was recovered by filtration at 20° C., washed and then dried. 95.5 g of the desired product was thus obtained which, after recrystallization, melts at 136° C.
Working in a manner similar to that described in the previous examples the following products were prepared:
4,5-diphenyl-1,2,4-triazol-3-one; m.p. 160° C.
4-phenyl-5-benzyl-1,2,4-triazol-3-one; m.p. 261°-262° C.
4-phenyl-5-isopropyl-1,2,4-triazol-3-one; m.p. 168° C.
4-(4-chlorophenyl)-5-methyl-1,2,4-triazol-3-one; m.p. 172°-174° C.
4,5-diethyl-1,2,4-triazolone; m.p. 127°-129° C.
4-(2-chlorophenyl)-5-phenyl-1,2,4-triazol-3-one; m.p. 209° C.
Patent CitationsCited PatentFiling datePublication dateApplicantTitleUS3514466 *Dec 14, 1966May 26, 1970Helmut StahleTriazolone compoundUS3857845 *Oct 15, 1973Dec 31, 1974Acraf1-{8 3-(4-metrachlorophenyl-1-piperazinyl)-propyl{9 -3,4-diethyl-{66 {11 -1,2,4-triazolin-5-oneUS4338317 *Mar 16, 1981Jul 6, 1982Mead Johnson & CompanyPhenoxyethyl-1,2,4,-triazol-3-one antidepressantsUS4596884 *Jun 3, 1985Jun 24, 1986Bristol-Myers Company4-(2-phenoxyethyl)-1,2,4-triazolone process intermediatesUS5094683 *Apr 29, 1991Mar 10, 1992Bayer AktiengesellschaftSulphonylaminocarbonyltriazolinones* Cited by examinerNon-Patent CitationsReference1Cohen, "Preparation of some 3-hydroxy, etc" CA 89: 43256 (1978).2 *Cohen, Preparation of some 3 hydroxy, etc CA 89: 43256 (1978).3Davidson, "A Preparation of 3-amino-4,5-diaryl, etc" CA 91: 107946u (1979).4 *Davidson, A Preparation of 3 amino 4,5 diaryl, etc CA 91: 107946u (1979).5Gehlen et al, "1,2,4-triazolin-5-ones, etc" CA 61: 10674 a,b. (1964).6 *Gehlen et al, 1,2,4 triazolin 5 ones, etc CA 61: 10674 a,b. (1964).7 *Journal of Heterocyclic Chemistry, vol. 22, No. 4, pp. 1121 1125, G.D. Madding, et al. Synthesis and X Ray Crystal Structure of a 2,4,5 trisubstituted 1,2,4 triazol 3 one (1985).8Journal of Heterocyclic Chemistry, vol. 22, No. 4, pp. 1121-1125, G.D. Madding, et al. "Synthesis and X-Ray Crystal Structure of a 2,4,5-trisubstituted 1,2,4-triazol-3-one" (1985).9Senet et al, "Process for the preparation of etc" CA 111: 7413f (1989).10 *Senet et al, Process for the preparation of etc CA 111: 7413f (1989).11 *VEB Fahlberg List, Herbicidal Compositions, etc C98: 174871 (1983).12VEB Fahlberg-List, "Herbicidal Compositions, etc" C98: 174871 (1983).* Cited by examinerReferenced byCiting PatentFiling datePublication dateApplicantTitleUS5900485 *Oct 15, 1997May 4, 1999Apotex, Inc.Methods for the manufacture of neofazodoneUS6384037Apr 7, 2000May 7, 2002Sepracor Inc.R-hydroxynefazodoneUS6465469Apr 7, 2000Oct 15, 2002Sepracor Inc.S-hydroxynefazodoneUS6465470Nov 19, 2001Oct 15, 2002Sepracor Inc.R-hydroxynefazodone* Cited by examinerClassifications U.S. Classification544/366, 548/264.6, 548/263.2International ClassificationC07D249/12Cooperative ClassificationC07D249/12European ClassificationC07D249/12Legal EventsDateCodeEventDescriptionMay 24, 1995ASAssignmentOwner name: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:NIGRO, ALBERTO;TOMASELLI, MAURO;REEL/FRAME:007498/0274Effective date: 19950404Dec 4, 2001FPAYFee paymentYear of fee payment: 4Dec 2, 2005FPAYFee paymentYear of fee payment: 8Oct 2, 2009FPAYFee paymentYear of fee payment: 12RotateOriginal ImageGoogle Home - Sitemap - USPTO Bulk Downloads - Privacy Policy - Terms of Service - About Google Patents - Send FeedbackData provided by IFI CLAIMS Patent Services

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Tx☆Oma (#47523779)	member for 2 years, 9 months, 8 days
54,741 Virtual Flowers
Virtual CemeteriesBeloved Purr Babies (3)Dear Ones (5)Great-Grandparents (4)Find A Grave FriendsAlice Morton, Allison Ford, Anita Bennich P..., Ann H., Aurora, Beautiful Savio..., Broken~♥~H..., dhb, Diana McDevitt ..., Eileen, EmilyAnn France..., Esther Kinder, Gina, Hans. ♥J&..., In Loving Memor..., J.A. & D.S., JASON Of Englan..., Johnny-Ren�, Joyce, Juliaღ, [View all Find A Grave Friends...]Messages left for Tx☆Oma (366)[Leave Message]
MaryHi, TxOma,Thank you for leaving my beloved cat Chuck a birthday greeting. I sincerely appreciate it!Take Care,MaryAdded by Mary on Mar 05, 2014 2:48 PMRuby RedRE: Hello,Hi, Sue! I know about these messages not going thru like they should. One time, mine went three times!! (Felt silly!!) Have been watching the Texas weather. Yes, ya'll aren't use to that stuff very often. When I lived in Houston, it seemed it always rained. I was only about 15 at the time so can't quit remember the months. I'm basically from East Texas. Angelina county. Was home about 3 years ago. Had planned on going back this June again but our Maya is terminally ill and I just won't leave her. Now, we wait. Sure can't wait 'til Spring!!! It's been a harsh, cold time here. Take care!! Hugs, LindaAdded by Ruby Red on Mar 05, 2014 1:53 AMRuby RedRE: Hello,Hey, how are you? I sure hope it's warmer where you are!!Added by Ruby Red on Mar 03, 2014 12:52 PMDawnMargot Opitz KimmelmannThank you so much for the lovely token left on my mothers page.It is very much appreciated.Added by Dawn on Mar 01, 2014 2:53 AMRoxyThank youThank you so much for remembering & leaving Yannis an angel day token.Your kindness has touched my heart on this very sad day.RoxyAdded by Roxy on Feb 27, 2014 12:35 AMdhbThank You... so much for remembering my grandmother on her Angel Day, and the many tokens you've left my family. So appreciated! Big *hugs* -DianeAdded by dhb on Feb 24, 2014 1:39 AMDiggerRE: Ram-A-LamIf you look, you will also see a token for Kit, and your other cat. I didn't want to show partiality. ;-)Added by Digger on Feb 14, 2014 10:08 PMDiggerRE: Ram-A-LamRam-A-Lam is certainly welcome. You had some very special babies and I know you miss them a lot.Happy Valentines Day to you, as well.HugsElsieAdded by Digger on Feb 14, 2014 1:49 AMkathy barnettTHANKS!Thank you for visiting my Family & Friends' Memorials & for the beautiful flowers.....I appreciate your kindness!Added by kathy barnett on Feb 14, 2014 1:12 AMSaffron♥WingsThank YouDear Sue,Thank you so much for sharing your beautiful tokens. I always knew which ones were yours when I saw them in the upload. You are so kind to share them.Since the site is so slow on my end I did take some time and checked out your pinterest tokens. Beautiful and the ones for Valentines Day are just as darling. I am not a member of pinterest but managed to grab a couple as you can't right click and save but I have tricks in my browser and was able to save them. Thank you so very much and Happy Valentines Day to you and your family. Thanks for your many visits as well,Sincerely,Your friend,VikkiAdded by Saffron♥Wings on Feb 13, 2014 12:59 PM[View all messages...] Privacy Statement and Terms of Service Advertisement

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Motels in New Hope: Find 5 New Hope, PA Motels | Expedia
Motels in New Hope	New Hope
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Staff was great and accommodating. Enjoyed the breakfast in the morning.
4.4 out of 5 (383 reviews) My wife and I liked the Hotel but glass cups would be nicer than the paper cups being used.
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text:
Java / Hibernate - Write operations are not allowed in read-only mode - Stack Overflow
Here's the thing - sometimes, I get the following error when trying to update or create a new object with hibernate:
at org.springframework.orm.hibernate3.HibernateTemplate$12.doInHibernate(HibernateTemplate.java:696)
What is really strange is that, sometimes when updating an object with the method getHibernateTemplate().saveOrUpdate(object); it will work, but sometimes with the same object and by calling the same method it doesn't work, but it seems to depend on how I get the object in the first place.
Example: let's say I have a table with 3 fields: id, type, length. What can happen is that, if I get the object by the id and update the length, then it will work. If I get it by the type and update the length, then it won't work. So what I've been doing so far to avoid the problem is to fetch the object the method that does not cause a problem later, but this is becoming more and more annoying to try and find a way that works.
Also, now I have this exception when trying to create an object (but not all of them, just on one specific table), and can't find a way for a workaround. And I tried to add @Transactional(readOnly = false) in the transaction but it didn't change anything, and displaying the mode was saying that I wasn't in read-only anyway.
Edit 26th of July:
here's some configuration related to hibernate
<prop key="jdbc.fetch_size">20</prop>
<prop key="jdbc.batch_size">25</prop>
<prop key="cglib.use_reflection_optimizer">true</prop>
<prop key="connection.autoReconnect">true</prop>
<prop key="connection.autoReconnectForPools">true</prop>
<prop key="connection.is-connection-validation-required">true</prop>
also, if it can help
<prop key="execute*">PROPAGATION_REQUIRED</prop>
Edit 31st of August:
The relevant code in my Class that extends HibernateDaoSupport, to save the objects is:
public void createObject(Object persisObj) {
getHibernateTemplate().save(persisObj);
java hibernate spring readonly share|improve this question edited Aug 31 '11 at 17:13
asked Jul 24 '11 at 22:22
Are you using @Cache with READ_ONLY mode? Or have a method/class annotated with @Transactional(readOnly = true) somewhere? I have ran into these sort of issues myself and found that these two configurations play a role on this error. Mostly if you load an object, modify it and persist it again. I am particularly not very fond of using HibernateTemplate, that also may be hiding some configuration in the background. If you past some snippets of your configuration I might be able to help.
Thanks T Man for taking the time to reply. So I've search for any of @Cache/@Transactional in my whole project, and there was no such thing (and I never put it in my project). I actually didn't configure hibernate or write the methods, but I'll add my configuration in the post now. Also, this error appears when creating some objects, but not all of them (always the same though), so it is not only related to updating an object
I changed the single session propery from view filter. Problem solved:
still My update is not working!!
I tried getHibernateTemplate().getSessionFactory().getCurrentSession().setFlushMode(FlushMode.AUTO); and my problem solved...
That error message is typically seen when using the Spring OpenSessionInViewFilter and trying to do persistence operations outside of a Spring-managed transaction. The filter sets the session to FlushMode.NEVER/MANUAL (depending on the versions of Spring and Hibernate you're using--they're roughly equivalent). When the Spring transaction mechanism begins a transaction, it changes the flush mode to "COMMIT". After the transaction completes, it sets it back to NEVER/MANUAL, as appropriate. If you're absolutely sure that this isn't happening, then the next most likely culprit is non-thread-safe use of a Session. The Hibernate Session must be used in only one thread. If it crosses over between threads, all kinds of chaos can happen. Note that an entity loaded from Hibernate can hold a reference to the Session in which it was loaded, and handing the entity across threads can thus cause the Session to be accessed from another thread, too.
Thanks for your answer. You seem to know a lot about this, and I'm a bit confused about your answer. So I'm using Eclipse to develop, what do you reckon I should do to either detect/correct the problem? what could I do to try and fix it?
Best way to start is probably to add an exception breakpoint on the InvalidDataAccessApiUsageException, and then debug the app and make it happen. Then check the stack to see how you got to the exception. Especially check to see how and where the session was opened and whether a transaction was started. You can tell some of it from the exception stacktrace, but having it live in a debugger is better.
Well I'm still stuck on this. I tried to debug the thing but really don't see what I can do from it. I don't see any session or whatsoever in there. Anybody else has suggestions?
I just stumbled onto this too. I needed to change the flush mode in Spring's OpenSessionInViewFilter to manual, and suddenly I started getting this exception. I found out that the problems were hapening in methods that were not annotated as @Transactional, so I guess that Spring implicitly treats all data access code outside such methods as read only. Annotating the method solved the problem.
Another way is to call the setCheckWriteOperations method on the HibernateTemplate object.
so I tried to add @Transactional to the method (see my edit post for the code): did not change anything. Then I tried to call setCheckWriteOperations(false); before the save, got the exception: java.sql.SQLException: Connection is read-only. Queries leading to data modification are not allowed. Then I tried to remove the ,readOnly part of the <prop key="get*">PROPAGATION_REQUIRED,readOnly</prop> (see my first edit) and it worked! With this, @Transactional and the check thing don't matter, but I guess this is not a good fix. Any idea why this is happening?
I really don't ave a clue. Your get* properties wouldn't by any chance create some new objects? Say, add an entry into a log database table or something similar?
hibernateTemplate.setCheckWriteOperations(false);
The error should go away as the template is not checking if you are using a transaction.
share|improve this answer edited Apr 19 '13 at 16:55
answered Apr 19 '13 at 16:36
but update is not working!!!
I tried getHibernateTemplate().getSessionFactory().getCurrentSession().setFlushMode(FlushMode.AUTO); and my problem solved.
I had the same problem and after one day of investigation I observed the following declaration
I removed mode="aspectj"
unfortunately I don't have a tx:annotation-driven tag in any of my config files
Maybe you must put it in your config file because in default way it has some wrong attribute values for your transaction manager. This problem is result of wrong configuration and you must find what's wrong
Use below bean for HibernateTemplate in application context.
<property name="sessionFactory" ref="mysessionFactory"></property>
<property name="checkWriteOperations" value="false"></property>
share|improve this answer answered Dec 19 '15 at 12:38
Below piece of code is worked for me.
5,400101631
user3198259
Not the answer you're looking for?	Browse other questions tagged java hibernate spring readonly or ask your own question.	asked
6HIbernate InvalidDataAccessApiUsageException - read-only mode1Write operations are not allowed in read-only mode (FlushMode.MANUAL): with grails hibernate3Read Only Database Connection with Hibernate0org.springframework.dao.InvalidDataAccessApiUsageException: Write operations are not allowed in read-only mode1Write operations are not allowed in read-only mode - Issue while persisting0Spring Write operations are not allowed in read-only mode0Spring/Hibernate Write operations are not allowed in read-only mode0“Write operations are not allowed in read-only mode” error : confused with Spring @Service @transaction @Repository and Hibernate1Write operations are not allowed in read-only mode (FlushMode.MANUAL)0Java / Hibernate - Write operations are not allowed in read-only mode Error

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text:
Commentary: Le Pen's Win May Be Just What France Needs - Bloomberg
Commentary: Le Pen's Win May Be Just What France Needs
The country must confront the largely taboo subject of assuring racial and religious minorities a seat at the national table
Shock. Shame. Or simply, Non! These are the words being tossed across the French political landscape in the wake of the first-round electoral triumph of extreme right-wing leader Jean-Marie Le Pen on Apr. 21. Never before has the French Hard Right drawn such a high percentage of the vote, and never has one of its leaders made it to the runoff in a Presidential election. "Yes, alas," lamented the editor-in-chief of the influential French daily Le Monde in a post-election front-page editorial, "times are changing for the worse for France."
But are they? More than anything else, Le Pen's showing must be interpreted as an urgently overdue wake-up call--a prise de conscience, as they say in Paris--for a country that has long prided itself on being in the vanguard of so many political, economic, and cultural trends in Europe and the world. That's why this all could have a happy ending. In fact, if French leaders summon the courage and determination, they can make this a positive turning point for modern France and for Europe.
That means movement--right now--in the two vital areas that make France an anomaly in Europe. One is the pressing need for younger, fresher faces among the lineup of France's sclerotic political leaders. The other is the urgent necessity to recognize that today's France is a vibrant, multiethnic, multireligious reality.
The two issues are closely related, and much, in fact, is brewing beneath the surface. In both the Center Right and Center Left, a new generation of forward-looking thirty- and fortysomethings has been waiting impatiently in the wings, crowded out by political barons such as President Jacques Chirac, who was appointed to his first government position in 1969. Now, things could start to change. On the Right, a potential new prime minister is 46-year-old Neuilly Mayor Nicolas Sarkozy. On the Left, the decision by vanquished 65-year-old Prime Minister Lionel Jospin to leave political life opens the door to younger leaders.
France also must confront the largely taboo subject of assuring the country's racial and religious minorities, particularly the roughly 10% of the population with a North African Muslim background, a seat at the national table. Misguided social planning led to vast, government-built suburban ghettos ringing French cities. The inward-looking political elite has never reached out to these minorities. "Unlike Britain and Germany, there is simply no representation in the main French political parties of people with African and Arab origins," says Paris banker Omar Benderra, who was born in Algeria. "There is just a total lack of visibility."
This blindness has bred stupidity. France's Center Left government, for example, too scared to stir up the social pot, has looked the other way during recent anti-Semitic violence. Politicians also ignored early signs of social disturbance in the housing projects. The first vandals arrested for torching synagogues, seriously criminal acts in other civilized countries, got off with minor suspended sentences. Instead, Paris should have sent a firm message that such behavior is totally unacceptable.
The political turbulence of the France of 2002 is in some ways reminiscent of the brutal jolt America received in the late 1960s, when race riots devastated inner cities in the U.S. Then, a traumatized America began to come to terms with the destructiveness of racial exclusion. It was something that the white Republican and Democratic establishments of the time had ignored for far too long.
Just as Le Pen is shocking France's conscience today, George C. Wallace and his segregationist American Independent Party shocked the U.S. by picking up some 10 million votes, or 14% of the electorate, in the 1968 Presidential election. In some ways, the U.S. is still working out the repercussions. France may be only just beginning.
Rossant covers European politics.

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text:
BASEBALL; Gooden Sputters Again - The New York Times
Archives|BASEBALL; Gooden Sputters Again
https://nyti.ms/29jT7Zl
BASEBALL; Gooden Sputters Again
By CLAIRE SMITH and SPECIAL TO THE NEW YORK TIMES JUNE 3, 1990
June 3, 1990, Page 008001 The New York Times Archives
Dwight Gooden is struggling and the Mets continue to look for answers, literally from head to toe.
After a 5-4 loss to the Phillies tonight, both the pitcher and his manager, Bud Harrelson, admitted that Gooden's broken middle toe on his left foot has had the pitcher laboring at less than full strength over the course of three successive subpar outings.
The Phillies' hitters mauled Gooden tonight even though Gooden and his catcher, Mackey Sasser, said the pitcher had thrown the ball with good velocity. Gooden's biggest antagonist was Len Dykstra, the former Met, who collected three hits to raise his league-leading batting average to .405. He also scored two runs.
''The foot is not 100 percent,'' said Gooden, who was removed for a pinch-hitter in the seventh inning, ''but that's got nothing to do with what's taking place.''
What has taken place in three consecutive games in which Gooden allowed 12 runs, 10 of them earned?
Need 'a Little Better Command'
''I just need a little better command,'' Gooden said. ''It's not any worry. It's just going to take a little bit harder work between starts.''
Harrelson, after watching his pitcher give up nine hits, four earned runs and three walks to the Phillies in six innings, also wondered about the toe, which was broken May 19 when Sasser accidentally placed his chair on it. Harrelson's not so sure it isn't a cause for problems. Gooden's record is 3-5, with a 4.37 earned run average.
''I don't know, but I'll find out,'' Harrelson said. ''He's not driving the way he should all the time.''
Harrelson also speculated that Gooden's mechanics may be off and said he planned to discuss the situation with the pitching coach, Mel Stottlemyre.
''I'm not a pitching coach,'' Harrelson said, ''but I think it may be a little mechanical stuff. I don't think it's anything major. Maybe it's just my imagination.''
It was not anyone's imagination as they watched the Phillies halt a losing streak at five games. Nor was it anyone's imagination that Dykstra continued to punish major league pitchers. The center fielder, who was 3 for 4, has 68 hits in 41 games. Dykstra doubted he could stay there an entire season in such rarified territory.
''No one is going to hit .400, ever, playing major league baseball,'' Dykstra said. ''There's too many things going on, too many things you have to do and concentrate on.''
Concentrating Quite Well
For now, Dykstra is concentrating quite well at the plate. He opened the bottom of the first with a double down the left-field line, the 25th hit in a 15-game hitting streak, the longest in the National League this season.
Dykstra moved to third on a groundout, then scored on a single by Rickey Jordan. The Phillies' first baseman, who has enjoyed uncanny success against Gooden, collected the run batted in by ricocheting the hit off of Gooden's pitching hand, his fifth hit in nine career times at bat against Gooden.
''That could have been the turning point right there,'' Gooden said. ''I pitched good, then I jammed Jordan and still got hurt.''
Homer for Strawberry
The Phillies then used the first of two stolen bases in the inning to build their second run as Jordan swiped second, then scored on John Kruk's ground single into center.
The Mets tied the score in the third. Daryl Boston, who has solidified his share of the center field job by hitting right-handers well, collected a one-out hit against the Phillies' right-hander, Ken Howell. After Boston stole second with two out, Darryl Strawberry lined a 1-2 pitch into the black tarpaulin hanging behind the fence in right-center. The home run was Strawberry's eighth of the season and fourth in nine games.
The Phillies quickly rebuilt the two-run lead in the bottom of the third, using a Dykstra single, a run-scoring double by Tom Herr and a sacrifice fly by Charlie Hayes. The Mets pulled within one in the seventh when Boston hit a mammoth home run to right-field mezzanine level, then fell back again when Darren Daulton hit a homer off Jeff Musselman in the eighth.
Another former Met, Roger McDowell, recorded his league-leading 13th save but not before making it a bit more interesting by allowing a run in the ninth. With two out, Howard Johnson tripled and then scored on a single by Boston, the centerfielder's third hit.
A version of this article appears in print on June 3, 1990, on Page 8008001 of the National edition with the headline: BASEBALL; Gooden Sputters Again. Order Reprints| Today's Paper|Subscribe

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text:
Amnesty: Muslim exodus in CAR 'ethnic cleansing' | Daily Mail Online
Amnesty: Muslim exodus in CAR 'ethnic cleansing'
Published: 10:58 EST, 12 February 2014 | Updated: 10:59 EST, 12 February 2014
DAKAR, Senegal (AP) — The exodus of tens of thousands of Muslims from Central African Republic amounts to "ethnic cleansing," Amnesty International said Wednesday, warning that the sectarian bloodshed now underway despite the presence of thousands of peacekeepers is a "tragedy of historic proportions."
"No one accepts or will accept a partition" into a Muslim north and Christian south, he said.
Their concerns were echoed Wednesday by Human Rights Watch, which also has been documenting the violence and has helped get Muslims to safety in many circumstances. The group said that the major gold trading center of Yaloke had previously been home to 30,000 Muslims and had eight mosques before fighting erupted. As of early February, just one mosque remained and less than 500 Muslims were still in town — under the protection of French peacekeepers.
Associated Press writers Hippolyte Marboua in Bangui, Central African Republic and Edith M. Lederer at the United Nations contributed to this report.
French Defense Minister Jean-Yves le Drian visits a container full of confiscated weapons at the airport in Bangui, Central African Republic, Wednesday Feb. 12, 2014. It is le Drian's third trip to Bangui since the beginning of Operation Sangaris Dec. 5, 2013. (AP Photo/Jerome Delay)
French Defense Minister Jean-Yves le Drian , right, Central African Republic Interim President Catherine Samba Panza , left, and the commander of French troops in the Central African Republic General Francisco Soriano, center, sit in a helicopter before taking off to Mbaike, some 80 kms (50 miles) south of Bangui Wednesday Feb. 12, 2014. It is le Drian's third trip to Bangui since the beginning of Operation Sangaris on Dec. 5, 2013. (AP Photo/Jerome Delay)
French Defense Minister Jean-Yves le Drian Greets French helicopter crew at the airport in Bangui, Central African Republic, Wednesday Feb. 12, 2014. It is le Drian's third trip to Bangui since the beginning of Operation Sangaris on Dec. 5, 2013. (AP Photo/Jerome Delay)
French Defense Minister Jean-Yves le Drian meets with Central African Republic Interim President Catherine Samba Panza at the presidency in Bangui Wednesday Feb. 12, 2014. It is le Drian's third trip to Bangui since the beginning of Operation Sangaris on Dec. 5, 2013. (AP Photo/Jerome Delay)

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text:
Programmatic Refresh of a File System - CodeProject 11,113,749 members (70,913 online)
Programmatic Refresh of a File System shaman74, 17 Apr 2005
4.40/5 - 27 votes1 removedμ 4.28, σa 1.76 [?]
How to force the file system to refresh.	Introduction
This is a short article, written after many hours spent on the problem of refreshing a CD file system after burning. At the end, the solution I've found is very very simple, so I've decided to explain it here.
I've used a call to the BroadcastSystemMessage function to send a WM_DEVICECHANGE message to Windows (XP in my case). The function is defined as follows (found on MSDN):long BroadcastSystemMessage(
LPDWORD lpdwRecipients,
UINT uiMessage,
To set the correct parameters for the call, I've initialized a DEV_BROADCAST_VOLUME struct, which is defined as:typedef struct _DEV_BROADCAST_VOLUME {
DWORD dbcv_size;
DWORD dbcv_devicetype;
DWORD dbcv_reserved;
DWORD dbcv_unitmask;
WORD dbcv_flags;
} DEV_BROADCAST_VOLUME, *PDEV_BROADCAST_VOLUME;
The code of my function is here:bool RefreshFileSystem(char cdrive)
DEV_BROADCAST_VOLUME hdr;
hdr.dbcv_size       =  sizeof(DEV_BROADCAST_VOLUME);
hdr.dbcv_devicetype =  DBT_DEVTYP_VOLUME;
hdr.dbcv_reserved = 0;
cdrive = (char)_totupper(cdrive));  // thanks to Blake Miller
hdr.dbcv_unitmask = 1 << (cdrive-'A');
hdr.dbcv_flags  = DBTF_MEDIA;
result = BroadcastSystemMessage(BSF_NOHANG|BSF_POSTMESSAGE,
NULL, WM_DEVICECHANGE, DBT_DEVICEARRIVAL,
(LPARAM)&hdr);
return (result>=0);
I've heard of someone who used this kind of a solution but unfortunately the system crashed. I'm trying to find out what has caused the crash.
C# code - Works for me on network drives theit851412-Jun-11 18:00 Had to find a way to refresh the user's my computer windows to show drive mapping updates...
/// Changed for C# and to allow for network drive types.
/// <param name="localDrive"></param>
public static void RefreshDrive(string localDrive)
DEV_BROADCAST_VOLUME hdr = new DEV_BROADCAST_VOLUME();
// collect and clean the passed LocalDrive param
if (localDrive == null || localDrive.Length == 0)
throw new System.Exception("Invalid 'localDrive' passed, 'localDrive' parameter cannot be 'empty'");
char drive = localDrive[0];
hdr.dbcv_size = (uint)Marshal.SizeOf(hdr);
hdr.dbcv_devicetype = (uint)DevType.DBT_DEVTYP_NET;
hdr.dbcv_unitmask = (uint) 1 << (drive - 'A');
hdr.dbcv_flags = (ushort)Dbtf.DBTF_NET;
IntPtr hdrp = Marshal.AllocHGlobal(Marshal.SizeOf(hdr));
Marshal.StructureToPtr(hdr, hdrp, true);
MessageBroadcastRecipients recip = MessageBroadcastRecipients.BSM_ALLCOMPONENTS;
result = BroadcastSystemMessage(MessageBroadcastFlags.BSF_NOHANG | MessageBroadcastFlags.BSF_POSTMESSAGE,
ref recip, WM_DEVICECHANGE, (IntPtr)DBT_DEVICEARRIVAL, hdrp);
Marshal.FreeHGlobal(hdrp);
private static extern int BroadcastSystemMessage(MessageBroadcastFlags flags, ref MessageBroadcastRecipients lpInfo, uint Msg, IntPtr wParam, IntPtr lParam);
const uint WM_DEVICECHANGE = 0x0219;
const uint DBT_DEVICEARRIVAL = 0x8000;
enum DevType : uint
DBT_DEVTYP_OEM = 0,
DBT_DEVTYP_DEVNODE = 1,
DBT_DEVTYP_VOLUME = 2,
DBT_DEVTYP_PORT = 3,
DBT_DEVTYP_NET = 4,
enum Dbtf : uint
DBTF_MEDIA = 0x0001,
DBTF_NET = 0x0002,
enum MessageBroadcastFlags : uint
BSF_QUERY = 0x00000001,
BSF_IGNORECURRENTTASK = 0x00000002,
BSF_FLUSHDISK = 0x00000004,
BSF_NOHANG = 0x00000008,
BSF_POSTMESSAGE = 0x00000010,
BSF_FORCEIFHUNG = 0x00000020,
BSF_NOTIMEOUTIFNOTHUNG = 0x00000040,
BSF_ALLOWSFW = 0x00000080,
BSF_SENDNOTIFYMESSAGE = 0x00000100,
BSF_RETURNHDESK = 0x00000200,
BSF_LUID = 0x00000400
enum MessageBroadcastRecipients : uint
BSM_ALLCOMPONENTS = 0x00000000,
BSM_VXDS = 0x00000001,
BSM_NETDRIVER = 0x00000002,
BSM_INSTALLABLEDRIVERS = 0x00000004,
BSM_APPLICATIONS = 0x00000008,
BSM_ALLDESKTOPS = 0x00000010
public uint dbcv_size;
public uint dbcv_devicetype;
public uint dbcv_reserved;
public uint dbcv_unitmask;
public ushort dbcv_flags;
If you're unmapping a drive and remapping it to a different location, you must call RefreshDrive after the unmap and then after the mapping. If you do just one, the drive map may disappear or still show the old name.
// Unmap the existing drive, if it exists.
UnmapDrive(Drive);
NetworkDrive.RefreshDrive(Drive);
MapDrive(Drive, uncpath);
Possible crash causess Simon Owen25-Jun-06 22:58 Could the crash on some systems be because you're passing a pointer in LPARAM, and it'll only be valid in your own address space? It'll only crash if something is registered for those notifications and tries to use the pointer. There's some extra magic involved when the system sends them, to ensure it's valid for whatever is receiving it.
Another possibility is that you're POSTING the messages, but the pointer you're passing is to a stack variable that will be out of scope before some applications have processed the message. Making the structure variable static would help, but only if the pointer is actually valid to other processes anyway. query achalshah717-Mar-06 2:52 how can we write tcp related application in C/C++?
how can we specify SYN , FIN etc. flags of TCP header by using C/C++ SHChangeNotify Cabbi9-Jun-05 3:53 Hi,
take a look to the 'SHChangeNotify' API with the 'SHCNE_MEDIAINSERTED' flag, it will refresh the window explorer content. Isn't it what you needed? Ciao,
Cabbi can't refresh CDRW content Sergey Apollonov23-May-05 20:34 I'll try to use this method to refresh CDRW file system
after burning (without reloading CD), but unfortunately without any result.
The BroadcastSystemMessage procedure returns 1, but cd contents
does not refresh. I still need to reload CD to see a new content.
Please help me. I am using WINXP. Here is a text of my procedure (Delphi):
var hdr:TDevBroadcastVolume;
procedure refresh_cd(drive:string);
hdr.dbcv_size := sizeof(hdr);
hdr.dbcv_devicetype := DBT_DEVTYP_VOLUME;
hdr.dbcv_reserved := 0;
if length(drive)=0 then exit;
drive:=Uppercase(drive);
c:=drive[1];
hdr.dbcv_unitmask := 1 shl (ord(c)-ord('A'));
hdr.dbcv_flags := DBTF_MEDIA;
r := BroadcastSystemMessage(BSF_POSTMESSAGE or BSF_NOHANG,
WM_DEVICECHANGE, DBT_DEVICEARRIVAL,
longint(@hdr));
form1.memo1.lines.add(format('return=%d',[r]));
Code Correction : Drive Letter Blake Miller12-Apr-05 5:30 Your code assumes that the drive letter is upper case, but this is not enforced:
hdr.dbcv_unitmask = 1 << (cdrive-'A');
Maybe clients would consistently obtain correct results if you ensure the character is upper case before performing the bit shifting:
cdrive = (char)_totupper(cdrive));
hdr.dbcv_unitmask = 1 << (cdrive - 'A');
Re: Code Correction : Drive Letter shaman7412-Apr-05 6:17 very good suggestion!
I've changed the article's code.
visit http://www.genhome.org
Hhhhhhhhhhhhhhh ! Kochise8-Apr-05 0:24 The Windows bug I have for so long, because Windows don't refresh the CD content if you change it while you are in a modal dialog or the infamous SHBrowseForFolder !
My Lord ! So simple and elegant solution, thanks for the info !
Re: Hhhhhhhhhhhhhhh ! shaman748-Apr-05 0:32 Thanks!!!
ehmmm... rate my article, please! ------------------------------
Re: Hhhhhhhhhhhhhhh ! Outlook14-Apr-05 11:41 seems risky broadcasting a message thate embeds a pointer to a local (ie stack ) structure. martin l.
Re: Hhhhhhhhhhhhhhh ! shaman7414-Apr-05 21:52 mmmmh...
how would you make it? suggestions?
Re: Hhhhhhhhhhhhhhh ! MX-Mauro18-Apr-05 2:20 Hi,
Try putting the structure in a shared memory area adding this to your .cpp
#pragma comment(linker, "/SECTION:.SHARDATA,RWS")
#pragma data_seg(".SHARDATA")
And then using the global variable.
Mauro H. Leggieri Re: Hhhhhhhhhhhhhhh ! Andy N18-Apr-05 14:15 I'm pretty sure the O/S takes care of this:
(From MSDN documentation)
The system only does marshalling for system messages (those in the range 0 to WM_USER). To send other messages (those above WM_USER) to another process, you must do custom marshalling. To me that means that for any system message (e.g., WM_DEVICECHANGE) the O/S will take care of copying the data across process boundaries (marshalling). Last Visit: 31-Dec-99 19:00 Last Update: 26-Dec-14 15:16Refresh1
Views 51,702
Last Updated 18 Apr 2005	Article Copyright 2005 by shaman74Everything else

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text:
Patent US5533393 - Determination of dew point or absolute humidity - Google Patents
A microsensor system for determining water vapor content of the ambient atmosphere that uses a thin film suspended ceramic diaphragm structure featuring an embedded, patterned thin film heater, temperature sensor and an external film of an hygroscopic salt stabilized in a water-insoluble, crosslinked...http://www.google.com/patents/US5533393?utm_source=gb-gplus-sharePatent US5533393 - Determination of dew point or absolute humidity
Publication number US5533393 A
Application number US 08/372,577
Publication number 08372577, 372577, US 5533393 A, US 5533393A, US-A-5533393, US5533393 A, US5533393A
Inventors Ulrich Bonne, Nobuaki Honda, David Kubisiak, Thomas R. Ohnstein
Patent Citations (33), Non-Patent Citations (4), Referenced by (36), Classifications (16), Legal Events (4)
Determination of dew point or absolute humidity
US 5533393 A
1. A sensor for determining the absolute amount of water vapor in the ambient atmosphere comprising:
(a) a thin film suspended ceramic structure of silicon nitride;
(b) a substantially planar patterned thin film heater carried within said suspended ceramic structure and having an open central region;
(c) a pair of substantially planar patterned interdigital electrodes forming an electrode area carried by said suspended ceramic structure, said electrodes further being proximate said heater but on the surface of the suspended structure and having a pattern dimension contained within the pattern of said heater;
(d) a film of an hygroscopic salt stabilized in a crosslinked polymer matrix host material substantially insoluble in an humidity-induced solution of said salt and connecting said pair of patterned electrodes; and
(e) a patterned temperature sensing means for sensing the temperature of said salt, said temperature sensing means replacing said open central region of said heater.
2. The device of claim 1 wherein the electrodes are Au/Ag alloy.
9. A sensor for determining the absolute amount of water vapor in the ambient atmosphere comprising:
(b) a substantially planar patterned thin film heater carried within said suspended ceramic structure;
(e) a patterned temperature sensing means for sensing the temperature of said salt superimposed over the central region of said heater.
10. The method of depositing a film of metal alloy on a substrate from a plurality of targets of pure metals sought to be alloyed using a sputtering method which involves sequentially addressing the plurality of targets comprising the steps of:
(a) passing the substrate sequentially proximate to each of the plurality of targets for a plurality of cycles;
(b) depositing metal at each passage of the substrate proximate to a target, during the plurality of cycles to form a composite metal layer; and
(c) optionally annealing the composite metal layer to achieve a uniform concentration of the plurality of metals in the composite metal layer.
11. The method of claim 10 wherein the pure metals are Au and Ag.
24. A device for determining the dew point or absolute atmosphere water vapor content comprising:
(a) an hygroscopic salt exposed to exchange water vapor with the atmosphere but stabilized against washout in a retaining host material selected from the group consisting of porous alumina, magnesia, zirconia, silicon film and polymer matrices selected from those comprising crosslinked hydrophilic polymers substantially insoluble in a humidity induced solution of the hygroscopic salt;
(b) heating means proximate said hygroscopic salt for controlling the temperature of said salt to maintain a selected electrical parameter of said salt at a predetermined value independent variations in conditions of the atmosphere, wherein said parameter is selected from the group consisting of the electrical impedance components, resistance, and capacitance;
(c) means for measuring said selected electrical parameter of said salt;
(d) means for measuring the temperature of said salt and optionally of said atmosphere; and
(e) wherein the host material is a polymer matrix comprising polyvinyl alcohol crosslinked using malonic acid.
25. The device of claim 24 wherein the hygroscopic salt is LiCl.
26. A device for determining the dew point or absolute atmosphere water vapor content comprising:
(b) heating means proximate said hygroscopic salt for controlling the temperature of said salt to maintain a selected electrical parameter of said salt at a predetermined value independent variations in conditions of the atmosphere, wherein said parameter is selected from the group consisting of the electrical impedance components, resistance and capacitance;
(c) means for measuring said selected electrical parader of said salt;
(e) means for applying an AC signal at a plurality of frequencies to said sensor and means for measuring the selected electric parameter at two different frequencies to produce a ratio thereof.
27. The device of claim 26 wherein the electrical parameter is resistance.
29. A device for determining the absolute amount or water vapor in the atmosphere comprising:
(a) a thin film suspended ceramic structure;
(b) an hygroscopic salt exposed to the atmosphere but retained in a polymeric matrix host material substantially insoluble in an humidity-induced solution of said salt carried on said suspended ceramic structure;
(c) thin film heating means carried on said suspended ceramic structure proximate said hygroscopic salt for controlling the temperature thereof to maintain a selected electrical parameter of said salt at a predetermined value independent of variations in conditions of the atmosphere, wherein said parameter is selected from the group of impedance components consisting of electric resistance and capacitance;
(d) means for measuring said selected electrical parameter of said salt;
(e) means for measuring the temperature of said salt and optionally of said atmosphere; and
(f) wherein the polymeric matrix is a malonic acid crosslinked polyvinyl alcohol and the hygroscopic salt is LiCl.
30. A device for determining the absolute amount or water vapor in the atmosphere comprising:
(c) thin film heating means carried on said suspended ceramic structure proximate said hygroscopic salt for controlling the temperature thereof to maintain a selected electrical parameter of said salt at a predetermined value independent of variations in conditions of the atmosphere, wherein said para mer is selected from the group of impedance components consisting of electric resistance and capacitance;
(f) means for applying an AC signal at a plurality of frequencies to said sensor and means for measuring the selected electric parameter at two different frequencies to produce a ratio thereof.
31. The device of claim 30 wherein the impedance component selected is resistance.
37. A device for determining the absolute amount of water vapor in the atmosphere surrounding said device comprising:
(b) an hygroscopic salt exposed to the atmosphere but retained in a hydrophilic polymeric matrix host material as a separately incorporate salt substantially insoluble in an humidity-induced solution of said salt carried on said suspended ceramic structure;
(d) means for measuring said selected electrical parameter of said salt; and
(e) means for measuring the temperature of said salt and optionally of said atmosphere.
US3175400 * Sep 12, 1961 Mar 30, 1965 Honeywell Inc Humidity control apparatus having an energy limiting power source
US3664192 * Sep 8, 1969 May 23, 1972 Univ Utah State Dew point hygrometers
US4167725 * Aug 4, 1977 Sep 11, 1979 Sony Corporation Dew-sensing hygroscopic element
US4373339 * Dec 14, 1979 Feb 15, 1983 Trade Finance International Thermal energy conversion system and method utilizing unencased expandites
US4379406 * Sep 25, 1980 Apr 12, 1983 Bennewitz Paul F Relative humidity detector systems and method of increasing the calibration period of relative humidity detector systems
US4696796 * Sep 4, 1985 Sep 29, 1987 Shimadzu Corporation Moisture sensor
US4760368 * Apr 28, 1986 Jul 26, 1988 Sharp Kabushiki Kaisha Moisture sensor
1 Chapter 37, "Polycarboxylic Acids", Chemistry of Organic Compounds, pp. 791-792.
2 * Chapter 37, Polycarboxylic Acids , Chemistry of Organic Compounds, pp. 791 792.
3 Lambert, David K. et al, "An air flow sensor based on interface thermal wage propagation", J. Appl. Phys., 59(1) Jan. 1986, pp. 59-65.
4 * Lambert, David K. et al, An air flow sensor based on interface thermal wage propagation , J. Appl. Phys., 59(1) Jan. 1986, pp. 59 65.
US6428717 Aug 17, 2000 Aug 6, 2002 Yamatake-Honeywell Co., Ltd. Moisture sensitive element and method of manufacturing the same
US7077004 * Aug 2, 2004 Jul 18, 2006 E+E Elektronik Ges.M.B.H Method and device for measuring humidity
US20050028588 * Aug 2, 2004 Feb 10, 2005 Helmut Mitter Method and device for measuring humidity
DE19911293A1 * Mar 13, 1999 Oct 5, 2000 Peter Schultheis Verfahren und Vorrichtung zur Messung der Taupunkttemperatur
DE19911293C2 * Mar 13, 1999 Oct 18, 2001 Peter Schultheis Verfahren und Vorrichtung zur Messung der Taupunkttemperatur
EP0875752A1 * Apr 30, 1998 Nov 4, 1998 Yamatake-Honeywell Co. Ltd. Moisture sensitive element and method of manufacturing the same
EP1037038A1 * Mar 6, 2000 Sep 20, 2000 Joachim Dipl.-Ing. Beinhorn Method and device for measuring the dew-point temperature
U.S. Classification 73/335.02, 73/29.02, 374/28, 340/602, 73/29.01, 340/580, 324/689, 324/663, 338/34, 73/335.05
International Classification G01N25/66, G01N27/12
Cooperative Classification G01N25/66, G01N27/121
European Classification G01N25/66, G01N27/12B
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:BONNE, ULRICH;HONDA, NOBUAKI;KUBISIAK, DAVID;AND OTHERS;REEL/FRAME:007379/0490;SIGNING DATES FROM 19941101 TO 19941222


text:
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text: SAMPLE PLAY AUDIO SAMPLE http%3A%2F%2Fsamples.audible.com%2Fbk%2Frand%2F000441%2Fbk_rand_000441_sample.mp3+flashcontent1A2ZCMRMQ4W7BJ8242860 Wonderful Town: New York Stories from The New Yorker

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Auditor $70,000 Jobs, Employment in Chicago, IL
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text: SnmpB is an SNMP MIB browser written in QT. It supports SNMPv1, SNMPv2c & SNMPv3. SnmpB can browse/edit/load/add MIB files and can query SNMP agents. It also supports agent discovery, trap events, and graph plotting. 563 weekly downloads

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KOSNIC 11WATT ES/E27/EDISON SCREW CAP 110V ENERGY SAVING SPIRAL BULB | eBay Skip to main contenteBayShop by categoryEnter your search keywordAll CategoriesAdvanced or register':' style="margin-right:3px">Hello -User-.'.replace(/-User-/,escape(a)))+"")}catch(b){document.write("")}})();Hello (Sign in to bid or buy)Daily DealsCollectionsMy eBayExpand My eBaySummaryBids/OffersWatch ListWish ListAll ListsPurchase HistorySellingMy CollectionsFollowed SearchesMessagesCollect & Spend Learn moreSellExpand SellSell an itemSeller centreInternational sellingSeller protectionSeller FeesSell for CharityCommunityExpand CommunityAnswer CentreDiscussion BoardsGroupsNewsHelp & ContactExpand Help & ContactContact Us (Phone / Chat / E-mail)FAQsDelivery & ReturnsAsk the eBay CommunityResolution Centre Back to home page
Details about KOSNIC 11WATT ES/E27/EDISON SCREW CAP 110V ENERGY SAVING SPIRAL BULB
KOSNIC 11WATT ES/E27/EDISON SCREW CAP 110V ENERGY SAVING SPIRAL BULB
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9780692423066: MIRACLES? - DO THEY STILL HAPPEN TODAY?: God Miraculously Saving People’s Lives, Apparitions, Speaking In Tongues, Faith Healing - AbeBooks - Edward D Andrews: 0692423060
Edward D Andrews MIRACLES? - DO THEY STILL HAPPEN TODAY?: God Miraculously Saving People’s Lives, Apparitions, Speaking In Tongues, Faith Healing
ISBN 13: 9780692423066
MIRACLES? - DO THEY STILL HAPPEN TODAY?: God Miraculously Saving People’s Lives, Apparitions, Speaking In Tongues, Faith Healing
ISBN 10: 0692423060 ISBN 13: 9780692423066
Publisher: Christian Publishing House, 2015
Miracles were certainly a part of certain periods in Bible times. What about today? Are miracles still taking place. There are some very important subjects that surround this area of discussion that are often misunderstood. Andrews will answer such questions as does God step in and solve every problem if we are faithful? Does the Bible provide absolutes or guarantees in this age of imperfect humanity? Are miracles still happening today? Is faith healing Scriptural? Is speaking in tongues evidence of true Christianity? Is snake handling biblical? How are we to understand the indwelling of the Holy Spirit? The work of the Holy Spirit. Andrews offers his readers very straightforward, biblically accurate explanations for these difficult questions. If any have discussed such questions, without a doubt, they will be very interested in the Bible’s answers in this easy to read publication.
EDWARD D. ANDREWS (AS in Criminal Justice from Zane State, BS in Religion at Liberty Baptist Theological Seminary, MA in Biblical Studies at Temple-Baptist Seminary, and MDiv in Theology at Liberty Baptist Theological Seminary) is CEO and President of Christian Publishing House. He has authored thirty-one books and coauthored and updated and expanded three books, as well as over 200 articles.
1. Miracles? - Do They Still Happen Today?: God Miraculously Saving People's Lives, Apparitions, Speaking in Tongues, Faith Healing
Published by Christian Publishing House (2015)
Book Description Christian Publishing House, 2015. PAP. Condition: New. New Book. Shipped from US within 10 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. Seller Inventory # IQ-9780692423066
2. Miracles? - Do They Still Happen Today?: God Miraculously Saving People's Lives, Apparitions, Speaking in Tongues, Faith Healing (Paperback or Softback)
Published by Christian Publishing House 4/5/2015 (2015)
Book Description Christian Publishing House 4/5/2015, 2015. Paperback or Softback. Condition: New. Miracles? - Do They Still Happen Today?: God Miraculously Saving People's Lives, Apparitions, Speaking in Tongues, Faith Healing. Book. Seller Inventory # BBS-9780692423066
3. Miracles? - Do They Still Happen Today?: God Miraculously Saving People s Lives, Apparitions, Speaking in Tongues, Faith Healing (Paperback)
Book Description Christian Publishing House, 2015. Paperback. Condition: New. Language: English . Brand New Book ***** Print on Demand *****. Miracles were certainly a part of certain periods in Bible times. What about today? Are miracles still taking place. There are some very important subjects that surround this area of discussion that are often misunderstood. Andrews will answer such questions as does God step in and solve every problem if we are faithful? Does the Bible provide absolutes or guarantees in this age of imperfect humanity? Are miracles still happening today? Is faith healing Scriptural? Is speaking in tongues evidence of true Christianity? Is snake handling biblical? How are we to understand the indwelling of the Holy Spirit? The work of the Holy Spirit. Andrews offers his readers very straightforward, biblically accurate explanations for these difficult questions. If any have discussed such questions, without a doubt, they will be very interested in the Bible s answers in this easy to read publication. Seller Inventory # APC9780692423066
4. Miracles? - Do They Still Happen Today?: God Miraculously Saving People s Lives, Apparitions, Speaking in Tongues, Faith Healing (Paperback)
Book Description Christian Publishing House, 2015. Paperback. Condition: New. Language: English . Brand New Book ***** Print on Demand *****.Miracles were certainly a part of certain periods in Bible times. What about today? Are miracles still taking place. There are some very important subjects that surround this area of discussion that are often misunderstood. Andrews will answer such questions as does God step in and solve every problem if we are faithful? Does the Bible provide absolutes or guarantees in this age of imperfect humanity? Are miracles still happening today? Is faith healing Scriptural? Is speaking in tongues evidence of true Christianity? Is snake handling biblical? How are we to understand the indwelling of the Holy Spirit? The work of the Holy Spirit. Andrews offers his readers very straightforward, biblically accurate explanations for these difficult questions. If any have discussed such questions, without a doubt, they will be very interested in the Bible s answers in this easy to read publication. Seller Inventory # APC9780692423066
5. Miracles? - Do They Still Happen Today?: God Miraculously Saving People's Lives, Apparitions, Speaking In Tongues, Faith Healing
Book Description Condition: New. Seller Inventory # ria9780692423066_ing
6. Miracles? - Do They Still Happen Today?: God Miraculously Saving Peoples Lives, Apparitions, Speaking In Tongues, Faith Healing
Published by Christian Publishing House
Book Description Christian Publishing House. Paperback. Condition: New. 170 pages. Dimensions: 8.0in. x 5.0in. x 0.4in.Miracles were certainly a part of certain periods in Bible times. What about today Are miracles still taking place. There are some very important subjects that surround this area of discussion that are often misunderstood. Andrews will answer such questions as does God step in and solve every problem if we are faithful Does the Bible provide absolutes or guarantees in this age of imperfect humanity Are miracles still happening today Is faith healing Scriptural Is speaking in tongues evidence of true Christianity Is snake handling biblical How are we to understand the indwelling of the Holy Spirit The work of the Holy Spirit. Andrews offers his readers very straightforward, biblically accurate explanations for these difficult questions. If any have discussed such questions, without a doubt, they will be very interested in the Bibles answers in this easy to read publication. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Paperback. Seller Inventory # 9780692423066
7. MIRACLES? - DO THEY STILL HAPPEN TODAY?: God Miraculously Saving People?s Lives, Apparitions, Speaking In Tongues, Faith Healing
Book Description Christian Publishing House. PAPERBACK. Condition: New. 0692423060 Special order direct from the distributor. Seller Inventory # ING9780692423066
8. Miracles? - Do They Still Happen Today?: God Miraculously Saving People's Lives, Apparitions, Speaking in Tongues, Faith Healing
Book Description Christian Publishing House, 2015. PAP. Condition: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. Seller Inventory # IQ-9780692423066
9. MIRACLES? - DO THEY STILL HAPPEN TODAY?: God Miraculously Saving People?s Lives, Apparitions, Speaking In Tongues, Faith Healing
Book Description Christian Publishing House, 2015. Condition: New. book. Seller Inventory # M0692423060

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