After removing days of use with less than 5 puffs (n=259; 4.22% of day-use), the median rose only to 140 puffs/day. Globally, 80% of puffs/day ranged from 16 to 346, and 50% ranged from 55 to 236. Only very few users produced more than 600 puffs/day: in 99% of day-use the number of puffs/day was lower than 567.