Ricci had a small role in Terry Gilliam 's offbeat road movie , '' Fear and Loathing in Las Vegas '' ( 1998 ) , which marked her first collaboration with Johnny Depp . In 1998 , she also had starring roles in three independent features — '' Buffalo ' 66 '' , where she played Vincent Gallo 's unwitting abductee-turned-love interest ; John Waters ' satirical comedy '' Pecker '' , as the hard-nosed girlfriend of Edward Furlong ; and Don Roos ' black comedy-drama '' The Opposite of Sex '' , playing the acid-tongued , manipulative Dede . For the latter , Ricci garnered critical acclaim and was nominated for a Golden Globe for Best Actress . '' Variety '' 's Todd McCarthy described her as " deadly funny " , and felt that she delivered her dialogue with " the skill of a prospective Bette Davis " . Several years later , '' Entertainment Weekly '' singled out her portrayal of Dede as one of the " Worst Oscar Snubs Ever "
Golden Globe
56th Golden Globe Awards
Christina Ricci