During the late 1990s Main Street became the center of Cincinnati 's dot-com boom , mostly due to its cheap rents and proximity to Main Street 's non-tech businesses . Nicknamed " Digital Rhine " , the area had at least 10 Internet startups , and one startup sold to eBay in 1999 for $ 85 million . Digital Rhine slowly disappeared after the dot-com bubble burst in 2001 . One by one most of Main Street 's businesses closed or relocated following the 2001 riots and the economic downturn that followed the September 11 attacks
September 11 attacks
September 11 attacks
History of Over-the-Rhine