Unlike 1940 , Roosevelt openly sought re-election in 1944 , and he faced little opposition for the Democratic nomination . He easily won the presidential nomination of the 1944 Democratic National Convention , making him the first person to serve as a major party nominee in four separate presidential elections . Roosevelt favored Henry Wallace or James Byrnes as his running mate in 1944 , but Wallace was unpopular among conservatives in the party , while Byrnes was opposed by liberals and many Catholics . At the behest of party leaders , Roosevelt accepted Missouri Senator Harry S. Truman , who was acceptable to all factions of the party . Truman was best known for his battle against corruption and inefficiency in wartime spending as the head of the Truman Committee
1944 Democratic National Convention
1944 Democratic National Convention
Presidency of Franklin D. Roosevelt, third and fourth terms