Freeway segments along the Redwood Highway portion of US 101 are not as prevalent as along the Los Angeles-San Francisco route . A notable segment of the old US 101 alignment is SR 254 , also known as the Avenue of the Giants , in Humboldt Redwoods State Park . The freeway bypassing this scenic route , surrounded by towering Coast Redwoods , was completed in 1960 . Several bridges along the segment of highway running along the Eel River were destroyed during the Christmas flood of 1964
Christmas flood of 1964
Christmas flood of 1964
U.S. Route 101 in California