The change in national ownership did not bode well for the earlier Shawnee settlers . In 1825 they were removed permanently when the U.S. government enacted the treaty with the Shawnee in 1825 . This treaty , whose first signatory was William Clark of the Lewis and Clark Expedition fame , required that the Shawnee move to what is now known as Shawnee Mission , Kansas , on land that had previously belonged to the Osage tribes . The Osage tribe was the major Native American influence at the time of early European settlement , but by the 1830s most of the Native Americans had been displaced by white settlers . One of the Cherokee Trail of Tears routes passed through Sedgewickville , while another passed through Glennon and Zalma
Trail of Tears
Trail of Tears
Bollinger County, Missouri