The city remained Ottoman until the empire 's collapse , but was occasionally riven with internal feuds as well as attacks of cholera from 1823 . Around 20 – 25 percent of the population died of plague in 1827 . In 1850 a Muslim mob attacked Christian neighbourhoods , tens of Christians were killed and several churches looted . Though this event has been portrayed as driven by pure sectarian principles , Bruce Masters argues that such analysis of this period of violence is too shallow and neglects the tensions that existed among the population due to the commercial favor afforded to certain Christian minorities by the Tanzimat Reforms during this time which played a large role in creating antagonism between previously cooperative groups of Muslim and Christians in the eastern quarters of the city . Janissary rebels installed their own government when the Ottoman governor fled . The Ottomans took over the city weeks later killing some 5,000 . By 1901 , the city 's population was around 110,000
attacked
Massacre of Aleppo (1850)
Aleppo