Of the United States deaths , 1,892 have died in hostile action . Included in these numbers are 17 CIA operatives that were killed in Afghanistan : 17 by hostile fire , including seven in a suicide bomb attack on a military base , and one in an accident . The independent website iCasualties has put the total number of U.S. deaths at 2,313 . This number is by 9 higher than the Department of Defense 's tally which is 2,304 , when including the intelligence operatives . Since the start of U.S. military operations in Afghanistan , 20,320 U.S. service members have been wounded in hostile action , according to the Defense Department
suicide bomb attack on a military base
Camp Chapman attack
Coalition casualties in Afghanistan