The first recorded anti-Jewish riots took place in Alexandria in the year 38 CE , followed by the more known riot of 66 CE . Other notable events had already taken place in Europe during the Middle Ages . Jewish communities were targeted in the Black Death Jewish persecutions of 1348 – 1350 , in Toulon in 1348 , in Barcelona as well as in other Catalan cities , during the Erfurt massacre ( 1349 ) , the Basel massacre , massacres in Aragon and in Flanders , as well as the " Valentine 's Day " Strasbourg pogrom of 1349 . Some 510 Jewish communities were destroyed during this period , extending further to the Brussels massacre of 1370 . On Holy Saturday of 1389 , a pogrom began in Prague that led to the burning of the Jewish quarter , the killing of many Jews , and the suicide of many Jews trapped in the main synagogue ; the number of dead was estimated at 400 – 500 men , women and children
more known riot of 66 CE
Alexandria riot (66)
Pogrom