In January 2012 , Heigl stated in an interview that she had asked the producers of '' Grey 's Anatomy '' if she could return to the show to wrap up Izzie 's storyline . " I 've told them I want to return , " she said . " I really , really , really want to see where Izzie is . I just want to know what happened to her and where she went and what she 's doing now . My idea is that she actually , like , figures it out , and finds some success and does really well in a different hospital . She was always floundering , you know , and so she was always one step behind the eight ball and I want to see that girl take some power back . " She said she regretted leaving the show . " Oh yeah , sometimes , yeah . You miss it . I miss my friends . It was a great work environment ... and it becomes a family . I spent six years together with these people every day ... you grow up together , in a way ... I always felt that if they wanted me to come back and sort of wrap up that storyline ... I want them to know that I 'm down with it if they want me to , but I completely understand if it does n't necessarily work ... They 've got a lot of storylines going on there . " In 2013 , she appeared alongside Robert De Niro , Diane Keaton and Susan Sarandon in '' The Big Wedding '' , a comedy about an estranged family reuniting for a ceremony . A very poor critical and commercial reception greeted the film upon its release — it holds a 7 % rating on film review aggregator Rotten Tomatoes and only made US$ 7.5 million in its opening weekend — and for her role , Heigl was nominated for Worst Supporting Actress at the 34th Golden Raspberry Awards . In June 2013 , she began appearing in a television commercial for Vicks ' ZzzQuil
34th Golden Raspberry Awards
34th Golden Raspberry Awards
Katherine Heigl