The album 's lead single , " SexyBack " , was performed by Timberlake at the opening of the 2006 MTV Video Music Awards and reached number-one on the '' Billboard '' Hot 100 , where it remained for seven consecutive weeks . " My Love " , the album 's second single , also produced by Timbaland and featuring rapper T.I. , reached number-one on the Hot 100 , as did third single " What Goes Around ... Comes Around " . The song is reported to have been inspired by the break-up of his childhood friend and business partner , Trace Ayala , with actress Elisha Cuthbert . In October 2006 , Timberlake said that he would focus on his music career rather than his film roles , specifying that leaving the music industry would be a " dumb thing to do at this point " . He was the special guest performer at the 2006 Victoria 's Secret Fashion Show where he sang " SexyBack " , " My Love " and " LoveStoned "
2006 MTV Video Music Awards
2006 MTV Video Music Awards
Justin Timberlake