The Treaty of Dewitt 's Corner did not stop all conflict between the American and the Cherokee peoples . In fact , groups of the Chickamauga band of the Cherokee led by Dragging Canoe refused to sign the treaty and continued attacks on the American settlements . A peaceful agreement with the Chickamauga Cherokees did not come until 1785 when the Treaty of Hopewell was signed . Regional conflicts between the American people and all Indigenous peoples in the eastern continental United States continued until the Indian Removal Act in 1830 led to the Trail of Tears
Trail of Tears
Trail of Tears
Cherokee War of 1776