The city of Sis ( modern-day Kozan , Adana , Turkey ) was the center of the Catholicosate of the Great House of Cilicia for more than six centuries , starting in 1293 when the Catholicosate moved from Hromgla to Sis . The monastery of St. Sophia of Sis , home of the Catholicosate , dominates the town in early 20th-century photographs . During the Armenian Genocide , in 1915 , the Armenian population in Cilicia was mostly destroyed . The last Catholicos to reside in Sis was Sahak II ( Catholicos from 1902 to 1939 ) . In 1921 , after renewed massacres of Armenians in Cilicia by Kemalist Turkey , Sahak II , with the surviving Armenian population , fled to find refuge in Syria
Armenian Genocide
Armenian Genocide
Holy See of Cilicia