The 1906 earthquake completely destroyed the area , and many of the quake 's fatalities occurred there . Following the quake , the area was rebuilt with wider than usual streets , as the focus was on the development of light to heavy industry . The construction of the Bay Bridge and U.S. Route 101 during the 1930s saw large swaths of the area demolished , including most of the original Rincon Hill
1906 earthquake
1906 San Francisco earthquake
South of Market, San Francisco