Christians in Syria make up about 10 % of the population . The country 's largest Christian denomination is the Eastern Orthodox Church of Antioch ( known as the Greek Orthodox Patriarchate of Antioch and All the East ) , closely followed by the Melkite Catholic Church , one of the Eastern Catholic Churches , which has a common root with the Eastern Orthodox Church of Antioch , and then by an Oriental Orthodoxy churches like Syriac Orthodox Church and Armenian Apostolic Church . There are also a minority of Protestants and members of the Assyrian Church of the East and Chaldean Catholic Church . The city of Aleppo is believed to have the largest number of Christians in Syria . In the late Ottoman rule , a large percentage of Syrian Christians emigrated from Syria , especially after the bloody chain of events that targeted Christians in particular in 1840 , the 1860 massacre , and the Assyrian genocide . According to historian Philip Hitti , approximately 900,000 Syrians arrived in the United States between 1899 and 1919 ( more than 90 % of them Christians ) . The Syrians referred include historical Syria or the Levant encompassing Syria , Lebanon , Jordan and Palestine
Assyrian genocide
Assyrian genocide
Christianity in Syria