Around 1513 , the first move to divide the lands of the Bairro Alto began , under the approval of Lopo Atouguia . Bartolomeu de Andrade and his wife Francisca Cordovil received permission to section-off plots for the construction of houses . The new urbanization would be designated '' Vila Nova de Andrade '' . After the establishment of a grid network of roads , the first houses began to be built , with the majority popping-up south of the '' Portas de Santa Catarina '' in 1514 . The remainder of the homes also began occupying plots along '' Rua das Flores '' , '' Rua do Cabo '' , '' Rua do Castelo '' , the consecutively named '' Rua Primeira '' , '' Segunda '' and '' Terceira '' , in addition to the '' Rua da Barroca do Mar '' . By 1527 , there were a total of 408 buildings in the area , totalling 1600 inhabitants . During the 1530s , the agglomeration began to spread towards the old '' Estrada de Santos '' ( now the '' Calçada do Combro '' ) , tracing or following to the north of this route , where it encountered '' Rua da Rosa '' , '' Rua da Atalaia '' , '' Rua dos Calafates '' ( now '' Rua Diário de Notícias '' ) , '' Rua das Gáveas '' , '' Rua do Norte '' and '' Rua de São Roque '' . The 1531 earthquake resulted in a need to increase the number of residential homes , speeding the growth of the Bairro . The first Jesuits arrived in Portugal in 1540 . In 1551 , the civil parishes of Mártires and Loreto included 2464 homes and 20132 inhabitants
1531 earthquake
1531 Lisbon earthquake
Bairro Alto