Q:70 y/o F DES placed 2 days ago has new onset dyspnea. Meds:atorvastatin 80mg/d,metop 50mg/d,ticagrelor 90mg BID, &amp; ASA 81mg/d. Team c/f ticag induced dyspnea &amp; would like to switch agents. What is the most appropriate loading dose/time to load from last ticag dose?