The last 7 years, I have lived VERY remote. I can go months without hanging w/anyone other than my husband. My life is lived in the thundering, glorious silence of the wilderness.
I get easily overwhelmed in large groups/cities now. It can take days to decompress from the experience. 
The upside, I am more tuned into the earth than I ever have been in my life. My awareness of the forest and what is in it around me is quite sharp.....