My main impression of Bryan Johnson has been that he is the most superlatively exhausting example of a tech bro who wastes his life trying to maximize every moment. But after watching the Netflix documentary about him, I found him eccentric, but a likable and sympathetic character. I can relate to having an off-beat personality that is not everyone’s cup of tea. If he wants to do this with his life, whatever. But I also think it’s ridiculous to presume that at the present moment, we know much more about how to live healthfully beyond just eating well, exercising, not drinking or smoking, getting proper sleep, living in an area without major pollution, and engaging in meaningful pursuits and not being lonely. Beyond that, all those supplements aren’t going to do much on average.