Glycine Improves sleep 

See Abstract below … here’s a summary of this study’s findings 
•Subject of Study:
•Investigates glycine, a non-essential amino acid with roles in both excitatory and inhibitory neurotransmission.
•Focuses on glycine’s effects on sleep quality, particularly in individuals with insomnia.
•Mechanisms of Action:
•Glycine acts via:
•N-methyl-D-aspartate (NMDA) type glutamate receptors.
•Glycine receptors.
•Human Study Findings:
•Glycine ingestion before bedtime:
•Significantly improved subjective sleep quality in individuals with insomnia.
•Animal Study Findings (Rats):
•Oral administration of glycine led to:
•Increased plasma and cerebrospinal fluid glycine concentrations.
•Significant decrease in core body temperature.
•Decrease in core temperature linked with increased cutaneous (skin) blood flow.
•Proposed Mechanism:
•Lower core body temperature:
•Suggested as a mechanism for glycine’s effect on sleep, as the onset of sleep involves a natural temperature decrease.
•Helps maintain a lower core body temperature during sleep.
•Pharmacological Studies:
•Examined the mechanisms of glycine’s effects on sleep in both rat models and human trials.
•Conclusion:
•Glycine demonstrates potential as a therapeutic amino acid for improving sleep quality through its neurochemical actions and temperature regulation effects.

This abstract highlights glycine’s dual mechanisms of action and its potential clinical applications for managing sleep disturbances.