They decrease the amount of HMG1 in a feedback loop. They increase the amount of HMG1 in a feedback loop. They disrupt the normal circadian rhythms. They disrupt the normal cell cycle.
I gave my students this multiple choice question: Asbestos fibers cause a cancer called mesothelioma in humans. The fibers kill cells that line lung tissue by causing programmed-cell death. When cells die this way, they release a chemical, HMG1, which causes an inflammatory response in other cells. During this inflammatory response, cells release chemicals that promote tumor growth. What conclusion can you draw about the chemicals released in the inflammatory response?

Only one answer is correct among these 4 choices:
- They decrease the amount of HMG1 in a feedback loop.
- They increase the amount of HMG1 in a feedback loop.
- They disrupt the normal circadian rhythms.
- They disrupt the normal cell cycle.

Could you tell me which one is correct?

They disrupt the normal cell cycle.