tokens: The objectives of this study were ( 1 ) to define the kinetics of NF kappa B activation by examining I kappa B alpha degradation and the nuclear translocation of p65 in response to A/R or redox imbalance ( induced by treatment of cells with diamide and buthionine sulfoximine ) and ( 2 ) to determine whether the signal for I kappa B alpha degradation , nuclear translocation of p65 , and E-selectin -mediated neutrophil adhesion is related to the activity of protein tyrosine kinase ( PTK ) , protein tyrosine phosphatase ( PTPase ) and/or protein kinase C ( PKC ) .