Title: FRET-based nanocommunication with luciferase and channelrhodopsin molecules for in-body medical systems,
Abstract: The paper is concerned with an in-body system gathering data for medical
purposes. It is focused on communication between the following two components
of the system: liposomes gathering the data inside human veins and a detector
collecting the data from liposomes. Foerster Resonance Energy Transfer (FRET)
is considered as a mechanism for communication between the system components.
The usage of bioluminescent molecules as an energy source for generating FRET
signals is suggested and the performance evaluation of this approach is given.
FRET transmission may be initiated without an aid of an external laser, which
is crucial in case of communication taking place inside of human body. It is
also shown how to solve the problem of FRET signals recording. The usage of
channelrhodopsin molecules, able to receive FRET signals and convert them into
voltage, is proposed. The communication system is modelled with molecular
structures and spectral characteristics of the proposed molecules and further
validated by using Monte Carlo computer simulations, calculating the data
throughput and the bit error rate.