Title: Kinetic model of selectivity and conductivity of the KcsA filter,
Abstract: We introduce a self-consistent multi-species kinetic theory based on the
structure of the narrow voltage-gated potassium channel. Transition rates
depend on a complete energy spectrum with contributions including the
dehydration amongst species, interaction with the dipolar charge of the filter
and, bulk solution properties. It displays high selectivity between species
coexisting with fast conductivity, and Coulomb blockade phenomena, and it fits
well to data.