Title: Classification of crystallization outcomes using deep convolutional neural networks,
Abstract: The Machine Recognition of Crystallization Outcomes (MARCO) initiative has
assembled roughly half a million annotated images of macromolecular
crystallization experiments from various sources and setups. Here,
state-of-the-art machine learning algorithms are trained and tested on
different parts of this data set. We find that more than 94% of the test images
can be correctly labeled, irrespective of their experimental origin. Because
crystal recognition is key to high-density screening and the systematic
analysis of crystallization experiments, this approach opens the door to both
industrial and fundamental research applications.