Title: TADPOLE Challenge: Prediction of Longitudinal Evolution in Alzheimer's Disease,
Abstract: The Alzheimer's Disease Prediction Of Longitudinal Evolution (TADPOLE)
Challenge compares the performance of algorithms at predicting future evolution
of individuals at risk of Alzheimer's disease. TADPOLE Challenge participants
train their models and algorithms on historical data from the Alzheimer's
Disease Neuroimaging Initiative (ADNI) study or any other datasets to which
they have access. Participants are then required to make monthly forecasts over
a period of 5 years from January 2018, of three key outcomes for ADNI-3
rollover participants: clinical diagnosis, Alzheimer's Disease Assessment Scale
Cognitive Subdomain (ADAS-Cog13), and total volume of the ventricles. These
individual forecasts are later compared with the corresponding future
measurements in ADNI-3 (obtained after the TADPOLE submission deadline). The
first submission phase of TADPOLE was open for prize-eligible submissions
between 15 June and 15 November 2017. The submission system remains open via
the website: this https URL, although since 15 November
2017 submissions are not eligible for the first round of prizes. This paper
describes the design of the TADPOLE Challenge.