Title: X-ray luminescence computed tomography using a focused X-ray beam,
Abstract: Due to the low X-ray photon utilization efficiency and low measurement
sensitivity of the electron multiplying charge coupled device (EMCCD) camera
setup, the collimator based narrow beam X-ray luminescence computed tomography
(XLCT) usually requires a long measurement time. In this paper, we, for the
first time, report a focused X-ray beam based XLCT imaging system with
measurements by a single optical fiber bundle and a photomultiplier tube (PMT).
An X-ray tube with a polycapillary lens was used to generate a focused X-ray
beam whose X-ray photon density is 1200 times larger than a collimated X-ray
beam. An optical fiber bundle was employed to collect and deliver the emitted
photons on the phantom surface to the PMT. The total measurement time was
reduced to 12.5 minutes. For numerical simulations of both single and six fiber
bundle cases, we were able to reconstruct six targets successfully. For the
phantom experiment, two targets with an edge-to-edge distance of 0.4 mm and a
center-to-center distance of 0.8 mm were successfully reconstructed by the
measurement setup with a single fiber bundle and a PMT.