Title: Computer Assisted Localization of a Heart Arrhythmia,
Abstract: We consider the problem of locating a point-source heart arrhythmia using
data from a standard diagnostic procedure, where a reference catheter is placed
in the heart, and arrival times from a second diagnostic catheter are recorded
as the diagnostic catheter moves around within the heart. We model this
situation as a nonconvex feasibility problem, where given a set of arrival
times, we look for a source location that is consistent with the available
data. We develop a new optimization approach and fast algorithm to obtain
online proposals for the next location to suggest to the operator as she
collects data. We validate the procedure using a Monte Carlo simulation based
on patients' electrophysiological data. The proposed procedure robustly and
quickly locates the source of arrhythmias without any prior knowledge of heart
anatomy.