Title: PRE-render Content Using Tiles (PRECUT). 1. Large-Scale Compound-Target Relationship Analyses,
Abstract: Visualizing a complex network is computationally intensive process and
depends heavily on the number of components in the network. One way to solve
this problem is not to render the network in real time. PRE-render Content
Using Tiles (PRECUT) is a process to convert any complex network into a
pre-rendered network. Tiles are generated from pre-rendered images at different
zoom levels, and navigating the network simply becomes delivering relevant
tiles. PRECUT is exemplified by performing large-scale compound-target
relationship analyses. Matched molecular pair (MMP) networks were created using
compounds and the target class description found in the ChEMBL database. To
visualize MMP networks, the MMP network viewer has been implemented in COMBINE
and as a web application, hosted at this http URL.