Detailed, controlled, and documented self-experimentation in dermatology.
Because the skin is easily available, the combination of frequent periods of critical observation, the dermatologist's clinical experience, and carefully controlled documentation of these observations allow for self-experimentation in dermatologic disorders on the part of clinicians. The practical value of such self-experimentation has been shown over many years, especially by the use of skin surface microscopy at moderate magnification to examine various lesions; to document sensitization experiments with nickel, Japanese lacquer, and nitrogen mustard; to examine prolonged use of topical fungicides for the treatment of onychomycoses; and to contribute to extensive and continuing experiments in laser medicine.