Chronic ethanol feeding and diamine oxidase activity in rat brain and liver.
The activity of diamine oxidase, the principal enzyme for diamine catabolism, was evaluated in brain and liver from male rats fed nutritionally complete diets, of which 36% of total calories was given as ethanol or as isocaloric carbohydrates for 4 months. Ethanol caused an increase in diamine oxidase activity in the brain and a decrease in the liver, tissues with a low and high rate of ethanol oxidation, respectively.